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Conserved domains on  [gi|446860347|ref|WP_000937603|]
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IS91 family transposase [Escherichia coli]

Protein Classification

IS91 family transposase( domain architecture ID 1750273)

IS91 family transposase is the prototype element of a family of bacterial insertion sequences that transpose by a rolling-circle mechanism.

Gene Ontology:  GO:0003677|GO:0004803|GO:0006313
PubMed:  19709290|20215432

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
transpos_IS91 NF033538
IS91 family transposase;
5-376 8.54e-157

IS91 family transposase;


:

Pssm-ID: 468069 [Multi-domain]  Cd Length: 376  Bit Score: 446.40  E-value: 8.54e-157
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446860347   5 FADIFQQGNRWLNWLEKQpEGSVRPVVIESVTKIMACGTTLMGYTQWCCSSpdCSHIKKVCFRCKSRSCPHCGVKAGAQW 84
Cdd:NF033538   1 LKDIFEANQHWDAFLAQH-GGRLRPVQLEAVTKMLACRTSALGGHHYRCDN--CGHVKYVYNSCKSRHCPSCGAKATEQW 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446860347  85 IQYLLSLVPDCPWQHIVFTLPCQYWSLVFHNRR-LLAEMSRIAADVIQEICRQAD--VVPGIFTVIHTWGRDQEWHPHIH 161
Cdd:NF033538  78 IAKQQAELLPCPYRHVVFTLPDELWPLARHNRAwLLGALFRSAADTLLTFAKNRRhlLEIGAFAVLHTWGRRLNWHPHLH 157
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446860347 162 LSTTTGGVTSDHTWKN----LHFYARKVMSMWRYRITRLLSRKYPDLVIPDALAAEGSSKRDWNRFLDSHYRRGWNVNVS 237
Cdd:NF033538 158 LLVTAGGLDEDGRWKKckggILFPAKALSKVWRAKFLTLLRQAYDAGELFPAELAHIKLPSAWNKFLLGLYPRGWVVHAK 237
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446860347 238 RVMDNATHVAVYFGSYLKKPPVPMSRLEHYAGqDEIGLRYNSHRTKREEYLVMSGDEFMERFSWHVADKGFRMVRYYGFL 317
Cdd:NF033538 238 KKTGNGRQVLEYLGRYLKRPAISNSRLRHYDG-GEVTFRYKDHRTKGTKTLTLSPDEFIRRFLQHVPPKGFRRIRYYGFL 316
                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 446860347 318 SPVKRRLLEDVVYV-ITETVRKTAMQIRWRGMYQRLLKVDPLKCILCGGQMRFTGLKRGY 376
Cdd:NF033538 317 ANRSRGRALPTVYAaLPEPPPKKAAPLVFAQMLKRLLKVDPPECPLCGGRMVFIAFIRGP 376
 
Name Accession Description Interval E-value
transpos_IS91 NF033538
IS91 family transposase;
5-376 8.54e-157

IS91 family transposase;


Pssm-ID: 468069 [Multi-domain]  Cd Length: 376  Bit Score: 446.40  E-value: 8.54e-157
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446860347   5 FADIFQQGNRWLNWLEKQpEGSVRPVVIESVTKIMACGTTLMGYTQWCCSSpdCSHIKKVCFRCKSRSCPHCGVKAGAQW 84
Cdd:NF033538   1 LKDIFEANQHWDAFLAQH-GGRLRPVQLEAVTKMLACRTSALGGHHYRCDN--CGHVKYVYNSCKSRHCPSCGAKATEQW 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446860347  85 IQYLLSLVPDCPWQHIVFTLPCQYWSLVFHNRR-LLAEMSRIAADVIQEICRQAD--VVPGIFTVIHTWGRDQEWHPHIH 161
Cdd:NF033538  78 IAKQQAELLPCPYRHVVFTLPDELWPLARHNRAwLLGALFRSAADTLLTFAKNRRhlLEIGAFAVLHTWGRRLNWHPHLH 157
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446860347 162 LSTTTGGVTSDHTWKN----LHFYARKVMSMWRYRITRLLSRKYPDLVIPDALAAEGSSKRDWNRFLDSHYRRGWNVNVS 237
Cdd:NF033538 158 LLVTAGGLDEDGRWKKckggILFPAKALSKVWRAKFLTLLRQAYDAGELFPAELAHIKLPSAWNKFLLGLYPRGWVVHAK 237
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446860347 238 RVMDNATHVAVYFGSYLKKPPVPMSRLEHYAGqDEIGLRYNSHRTKREEYLVMSGDEFMERFSWHVADKGFRMVRYYGFL 317
Cdd:NF033538 238 KKTGNGRQVLEYLGRYLKRPAISNSRLRHYDG-GEVTFRYKDHRTKGTKTLTLSPDEFIRRFLQHVPPKGFRRIRYYGFL 316
                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 446860347 318 SPVKRRLLEDVVYV-ITETVRKTAMQIRWRGMYQRLLKVDPLKCILCGGQMRFTGLKRGY 376
Cdd:NF033538 317 ANRSRGRALPTVYAaLPEPPPKKAAPLVFAQMLKRLLKVDPPECPLCGGRMVFIAFIRGP 376
Y2_Tnp pfam04986
Putative transposase; Transposases are needed for efficient transposition of the insertion ...
142-323 5.36e-41

Putative transposase; Transposases are needed for efficient transposition of the insertion sequence or transposon DNA. This family includes transposases IS1294 and IS801. This is a rolling-circle transposase.


Pssm-ID: 428238  Cd Length: 183  Bit Score: 143.19  E-value: 5.36e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446860347  142 GIFTVIHTWGRDQEWHPHIHLSTTTGGVTSDHTWKNLH----FYARKVMSMWRYR-ITRLLSRKYPDLVIPDALAAEgss 216
Cdd:pfam04986   1 GFIAVLHTWGRALNLHPHVHCLVPGGGLDEDGQWWASRggffLPVKALSRLFRGKlLETLRKAILRGKLKLGLLERP--- 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446860347  217 kRDWNRFLDSHYRRGWNVNVSRVMDNATHVAVYFGSYLKKPPVPMSRLEHYAGqDEIGLRYNSHRTKREEYLVMSGDEFM 296
Cdd:pfam04986  78 -SAFAYLLLKAWDKGWVVDAKVPFGGGRAVLEYLGRYIHRPAISNSRLASTDD-GQVTFRYKDYRGGRTKTMTLPPLEFI 155
                         170       180
                  ....*....|....*....|....*..
gi 446860347  297 ERFSWHVADKGFRMVRYYGFLSPVKRR 323
Cdd:pfam04986 156 RRFLQHVPPPGFHRIRYYGFLANSPNS 182
 
Name Accession Description Interval E-value
transpos_IS91 NF033538
IS91 family transposase;
5-376 8.54e-157

IS91 family transposase;


Pssm-ID: 468069 [Multi-domain]  Cd Length: 376  Bit Score: 446.40  E-value: 8.54e-157
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446860347   5 FADIFQQGNRWLNWLEKQpEGSVRPVVIESVTKIMACGTTLMGYTQWCCSSpdCSHIKKVCFRCKSRSCPHCGVKAGAQW 84
Cdd:NF033538   1 LKDIFEANQHWDAFLAQH-GGRLRPVQLEAVTKMLACRTSALGGHHYRCDN--CGHVKYVYNSCKSRHCPSCGAKATEQW 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446860347  85 IQYLLSLVPDCPWQHIVFTLPCQYWSLVFHNRR-LLAEMSRIAADVIQEICRQAD--VVPGIFTVIHTWGRDQEWHPHIH 161
Cdd:NF033538  78 IAKQQAELLPCPYRHVVFTLPDELWPLARHNRAwLLGALFRSAADTLLTFAKNRRhlLEIGAFAVLHTWGRRLNWHPHLH 157
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446860347 162 LSTTTGGVTSDHTWKN----LHFYARKVMSMWRYRITRLLSRKYPDLVIPDALAAEGSSKRDWNRFLDSHYRRGWNVNVS 237
Cdd:NF033538 158 LLVTAGGLDEDGRWKKckggILFPAKALSKVWRAKFLTLLRQAYDAGELFPAELAHIKLPSAWNKFLLGLYPRGWVVHAK 237
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446860347 238 RVMDNATHVAVYFGSYLKKPPVPMSRLEHYAGqDEIGLRYNSHRTKREEYLVMSGDEFMERFSWHVADKGFRMVRYYGFL 317
Cdd:NF033538 238 KKTGNGRQVLEYLGRYLKRPAISNSRLRHYDG-GEVTFRYKDHRTKGTKTLTLSPDEFIRRFLQHVPPKGFRRIRYYGFL 316
                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 446860347 318 SPVKRRLLEDVVYV-ITETVRKTAMQIRWRGMYQRLLKVDPLKCILCGGQMRFTGLKRGY 376
Cdd:NF033538 317 ANRSRGRALPTVYAaLPEPPPKKAAPLVFAQMLKRLLKVDPPECPLCGGRMVFIAFIRGP 376
Y2_Tnp pfam04986
Putative transposase; Transposases are needed for efficient transposition of the insertion ...
142-323 5.36e-41

Putative transposase; Transposases are needed for efficient transposition of the insertion sequence or transposon DNA. This family includes transposases IS1294 and IS801. This is a rolling-circle transposase.


Pssm-ID: 428238  Cd Length: 183  Bit Score: 143.19  E-value: 5.36e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446860347  142 GIFTVIHTWGRDQEWHPHIHLSTTTGGVTSDHTWKNLH----FYARKVMSMWRYR-ITRLLSRKYPDLVIPDALAAEgss 216
Cdd:pfam04986   1 GFIAVLHTWGRALNLHPHVHCLVPGGGLDEDGQWWASRggffLPVKALSRLFRGKlLETLRKAILRGKLKLGLLERP--- 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446860347  217 kRDWNRFLDSHYRRGWNVNVSRVMDNATHVAVYFGSYLKKPPVPMSRLEHYAGqDEIGLRYNSHRTKREEYLVMSGDEFM 296
Cdd:pfam04986  78 -SAFAYLLLKAWDKGWVVDAKVPFGGGRAVLEYLGRYIHRPAISNSRLASTDD-GQVTFRYKDYRGGRTKTMTLPPLEFI 155
                         170       180
                  ....*....|....*....|....*..
gi 446860347  297 ERFSWHVADKGFRMVRYYGFLSPVKRR 323
Cdd:pfam04986 156 RRFLQHVPPPGFHRIRYYGFLANSPNS 182
Zn_Tnp_IS91 pfam14319
Transposase zinc-binding domain; This domain is likely to be a zinc-binding domain. It is ...
8-104 6.79e-25

Transposase zinc-binding domain; This domain is likely to be a zinc-binding domain. It is found at the N-terminus of transposases belonging to the IS91 family.


Pssm-ID: 464134  Cd Length: 90  Bit Score: 97.25  E-value: 6.79e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446860347    8 IFQQGnrWLNWLEKqpeGSVRPVVIESVTKIMACGTTLMGYTQWCCssPDCSHIKKVCFRCKSRSCPHCGVKAGAQWIQY 87
Cdd:pfam14319   1 IFRRH--WDDYLAK---HSLSPHQRKALEAILNCRTAALGGHVYRC--EDCGHERIVYNSCRNRHCPSCQAKATEQWLER 73
                          90
                  ....*....|....*..
gi 446860347   88 LLSLVPDCPWQHIVFTL 104
Cdd:pfam14319  74 QQAELLPVPYFHVVFTL 90
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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