|
Name |
Accession |
Description |
Interval |
E-value |
| PRK01622 |
PRK01622 |
membrane protein insertase YidC; |
1-255 |
2.82e-127 |
|
membrane protein insertase YidC;
Pssm-ID: 179310 Cd Length: 256 Bit Score: 361.38 E-value: 2.82e-127
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446843294 1 MLKSYRTALVSLSLLLVFVLSGCSNAAPIDAHSTGIWDHYFVYPISFMIQFVAHHIpGASFGIAIIIMTLVIRSAMIPLA 80
Cdd:PRK01622 1 MLKSYRAVLVSLSLLLVLVLSGCSNAAPIDAHSDGFFDHYFVYPFSFLIQFVAHHI-GGSYGIAIIIVTLIIRSLMIPLA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446843294 81 VSQYRS----QAKMKKMQPELQKLKKKYgDVSKDLEKQKQYQKEMSELMKSGGWNPLA-GCWPIFIQMPIFSALYYAISR 155
Cdd:PRK01622 80 VSQYKSqrgmQEKMAVMKPELDKIQAKL-KVTKDLEKQKEYQKEMMELYKSGNINPLAmGCLPLLIQMPILSAFYYAIRR 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446843294 156 TEEIRTSSFLWVNLGHADpyHILPIIAALTTFIQMKVFQSNITAGEQVQMLKMQQIMMPAMILFMGFAAPSGLVLYWITG 235
Cdd:PRK01622 159 TEEIASHSFLWFNLGHAD--HILPIIAGLTYFIQMKVSQSNGTSPEQVQMLKIQGIMMPAMILFMSFAAPSALVLYWITG 236
|
250 260
....*....|....*....|
gi 446843294 236 NLFTMTQTIVLRRIMEREEL 255
Cdd:PRK01622 237 GLFLMGQTIVLRKVMEREEK 256
|
|
| YidC |
COG0706 |
Membrane protein insertase Oxa1/YidC/SpoIIIJ [Cell wall/membrane/envelope biogenesis]; |
37-254 |
1.20e-77 |
|
Membrane protein insertase Oxa1/YidC/SpoIIIJ [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440470 [Multi-domain] Cd Length: 212 Bit Score: 233.86 E-value: 1.20e-77
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446843294 37 WDHYFVYPISFMIQFVAHHIPgaSFGIAIIIMTLVIRSAMIPLAVSQYRSQAKMKKMQPELQKLKKKYGDvskdlEKQKQ 116
Cdd:COG0706 5 WFGFIAKPLFWLLNFLHSLVG--NWGLAIILLTLIVRLLLFPLTVKQYKSMAKMQELQPELKEIQEKYKD-----DPQKL 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446843294 117 yQKEMSELMKSGGWNPLAGCWPIFIQMPIFSALYYAISRTEEIRTSSFLWVN-LGHADPYHI-LPIIAALTTFIQMKVfq 194
Cdd:COG0706 78 -QQEMMKLYKEEGVNPLGGCLPMLIQMPIFIALYRVLRNSIELRHAPFLGIPdLSAPDPYYIfLPILMGVTMFLQQKL-- 154
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 446843294 195 snITAGEQVQMLKMQQIMMPAMILFMGFAAPSGLVLYWITGNLFTMTQTIVLRRIMEREE 254
Cdd:COG0706 155 --NPAPAQDPQQKKMMYIMPLMFLFFFLSFPAGLVLYWVVSNLLTIGQQLIINRRLDKKK 212
|
|
| yidC_oxa1_cterm |
TIGR03592 |
membrane protein insertase, YidC/Oxa1 family, C-terminal domain; This model describes ... |
60-246 |
2.08e-74 |
|
membrane protein insertase, YidC/Oxa1 family, C-terminal domain; This model describes full-length from some species, and the C-terminal region only from other species, of the YidC/Oxa1 family of proteins. This domain appears to be univeral among bacteria (although absent from Archaea). The well-characterized YidC protein from Escherichia coli and its close homologs contain a large N-terminal periplasmic domain in addition to the region modeled here. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 274665 [Multi-domain] Cd Length: 179 Bit Score: 224.28 E-value: 2.08e-74
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446843294 60 SFGIAIIIMTLVIRSAMIPLAVSQYRSQAKMKKMQPELQKLKKKYGDvskdlEKQKQyQKEMSELMKSGGWNPLAGCWPI 139
Cdd:TIGR03592 1 NWGLAIILLTIIVRLILLPLTLKQYKSMRKMQELQPKLKEIQEKYKE-----DPQKL-QQEMMKLYKEEGVNPLGGCLPL 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446843294 140 FIQMPIFSALYYAISRTEEIRTSSFLWV-NLGHADPYHILPIIAALTTFIQMKVfqsNITAGEQVQMLKMQQIMMPAMIL 218
Cdd:TIGR03592 75 LIQMPIFIALYQVLLRSIELRHAPFLWIiDLSSPDPYYILPILMGVTMFLQQKL---SPKGPPDPAQQKMMMYFMPLMFL 151
|
170 180
....*....|....*....|....*...
gi 446843294 219 FMGFAAPSGLVLYWITGNLFTMTQTIVL 246
Cdd:TIGR03592 152 FFFLSFPAGLVLYWVVSNLFTIIQQLII 179
|
|
| 5TM_YidC_Alb3 |
cd20070 |
Five transmembrane core domain of membrane protein insertase YidC, Alb3, and similar proteins; ... |
62-248 |
1.08e-71 |
|
Five transmembrane core domain of membrane protein insertase YidC, Alb3, and similar proteins; This group is composed of the bacterial and chloroplastic members of the YidC/Oxa1/Alb3 protein family of insertases, including bacterial YidC, and chloroplastic ALBINO3 (Alb3) and Alb3-like proteins such as ALBINO3-like protein 1 (also called Alb4). Membrane protein insertase YidC, also called foldase YidC or membrane integrase YidC, facilitates proper folding, insertion, and assembly of inner membrane proteins and complexes. Depending on the nature of the substrate, YidC functions in a Sec-independent (YidC only) or a Sec-dependent manner as part of a complex containing YidC, the SecYEG channel, and SecDFYajC. YidC from Gram-negative bacteria contains an extra transmembrane segment (TM1) at the N-terminus and a large periplasmic domain, located between TM1 and TM2, that adopts a beta-super sandwich fold that is found in sugar-binding proteins such as galactose mutarotase. Alb3 and Alb3-like proteins are required for the post-translational insertion of the light-harvesting chlorophyll-binding proteins (LHCPs) into the chloroplast thylakoid membrane. Alb3 acts independently and may also function cooperatively with the thylakoid cpSecYE translocase to insert proteins co-translationally into the thylakoid membrane, similar to bacterial YidC that can function with the SecYEG translocase. YidC/Oxa1/Alb3 family insertases contain a core domain of five transmembrane (5TM) segments that is essential to insertase function.
Pssm-ID: 410994 [Multi-domain] Cd Length: 181 Bit Score: 217.63 E-value: 1.08e-71
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446843294 62 GIAIIIMTLVIRSAMIPLAVSQYRSQAKMKKMQPELQKLKKKYGDvskdlEKQKQyQKEMSELMKSGGWNPLAGCWPIFI 141
Cdd:cd20070 1 GLAIILLTILIRLLLLPLTLKQYKSMKKMQELQPKIKEIQEKYKD-----DKQKL-QQEMMKLYKEHGVNPLGGCLPLLI 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446843294 142 QMPIFSALYYAISRTEEIRTSSFLWV--NLGHADPYHILPIIAALTTFIQMKVfqSNITAGEQVQMLKMQQIMMPAMILF 219
Cdd:cd20070 75 QMPIFIALYQVLRNSIELRGAPFLWWilDLSAPDPYYILPILMGVTMFLQQKL--TPTPTDDQAPQQKMMMYFMPVMFTF 152
|
170 180
....*....|....*....|....*....
gi 446843294 220 MGFAAPSGLVLYWITGNLFTMTQTIVLRR 248
Cdd:cd20070 153 IFLSFPSGLVLYWLVSNLFSIIQQLIINK 181
|
|
| 60KD_IMP |
pfam02096 |
60Kd inner membrane protein; |
61-248 |
2.53e-68 |
|
60Kd inner membrane protein;
Pssm-ID: 460443 [Multi-domain] Cd Length: 187 Bit Score: 209.25 E-value: 2.53e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446843294 61 FGIAIIIMTLVIRSAMIPLAVSQYRSQAKMKKMQPELQKLKKKYGDvskdlEKQKQyQKEMSELMKSGGWNPLAGCWPIF 140
Cdd:pfam02096 1 YGLAIILLTILIKLILFPLTYKQYKSMAKMQELQPEMKEIQEKYKD-----DRQKL-QQEMMKLYKKEGVNPLGGCLPML 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446843294 141 IQMPIFSALYYAISRTEEIR-TSSFLWV-NLGHADP-----YHILPIIAALTTFIQMKvfQSNITAGEQVQMLKMQQIMM 213
Cdd:pfam02096 75 IQMPIFIALYRVLRNSIELRhAPFFLWIaDLSAPDPisilhYYILPILMGVTMFLQQK--LTPAPQDQPPQMKMMMLYFM 152
|
170 180 190
....*....|....*....|....*....|....*
gi 446843294 214 PAMILFMGFAAPSGLVLYWITGNLFTMTQTIVLRR 248
Cdd:pfam02096 153 PLMFLFFFLNFPAGLVLYWVVSNLLSIGQQLIINR 187
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK01622 |
PRK01622 |
membrane protein insertase YidC; |
1-255 |
2.82e-127 |
|
membrane protein insertase YidC;
Pssm-ID: 179310 Cd Length: 256 Bit Score: 361.38 E-value: 2.82e-127
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446843294 1 MLKSYRTALVSLSLLLVFVLSGCSNAAPIDAHSTGIWDHYFVYPISFMIQFVAHHIpGASFGIAIIIMTLVIRSAMIPLA 80
Cdd:PRK01622 1 MLKSYRAVLVSLSLLLVLVLSGCSNAAPIDAHSDGFFDHYFVYPFSFLIQFVAHHI-GGSYGIAIIIVTLIIRSLMIPLA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446843294 81 VSQYRS----QAKMKKMQPELQKLKKKYgDVSKDLEKQKQYQKEMSELMKSGGWNPLA-GCWPIFIQMPIFSALYYAISR 155
Cdd:PRK01622 80 VSQYKSqrgmQEKMAVMKPELDKIQAKL-KVTKDLEKQKEYQKEMMELYKSGNINPLAmGCLPLLIQMPILSAFYYAIRR 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446843294 156 TEEIRTSSFLWVNLGHADpyHILPIIAALTTFIQMKVFQSNITAGEQVQMLKMQQIMMPAMILFMGFAAPSGLVLYWITG 235
Cdd:PRK01622 159 TEEIASHSFLWFNLGHAD--HILPIIAGLTYFIQMKVSQSNGTSPEQVQMLKIQGIMMPAMILFMSFAAPSALVLYWITG 236
|
250 260
....*....|....*....|
gi 446843294 236 NLFTMTQTIVLRRIMEREEL 255
Cdd:PRK01622 237 GLFLMGQTIVLRKVMEREEK 256
|
|
| YidC |
COG0706 |
Membrane protein insertase Oxa1/YidC/SpoIIIJ [Cell wall/membrane/envelope biogenesis]; |
37-254 |
1.20e-77 |
|
Membrane protein insertase Oxa1/YidC/SpoIIIJ [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440470 [Multi-domain] Cd Length: 212 Bit Score: 233.86 E-value: 1.20e-77
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446843294 37 WDHYFVYPISFMIQFVAHHIPgaSFGIAIIIMTLVIRSAMIPLAVSQYRSQAKMKKMQPELQKLKKKYGDvskdlEKQKQ 116
Cdd:COG0706 5 WFGFIAKPLFWLLNFLHSLVG--NWGLAIILLTLIVRLLLFPLTVKQYKSMAKMQELQPELKEIQEKYKD-----DPQKL 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446843294 117 yQKEMSELMKSGGWNPLAGCWPIFIQMPIFSALYYAISRTEEIRTSSFLWVN-LGHADPYHI-LPIIAALTTFIQMKVfq 194
Cdd:COG0706 78 -QQEMMKLYKEEGVNPLGGCLPMLIQMPIFIALYRVLRNSIELRHAPFLGIPdLSAPDPYYIfLPILMGVTMFLQQKL-- 154
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 446843294 195 snITAGEQVQMLKMQQIMMPAMILFMGFAAPSGLVLYWITGNLFTMTQTIVLRRIMEREE 254
Cdd:COG0706 155 --NPAPAQDPQQKKMMYIMPLMFLFFFLSFPAGLVLYWVVSNLLTIGQQLIINRRLDKKK 212
|
|
| yidC_oxa1_cterm |
TIGR03592 |
membrane protein insertase, YidC/Oxa1 family, C-terminal domain; This model describes ... |
60-246 |
2.08e-74 |
|
membrane protein insertase, YidC/Oxa1 family, C-terminal domain; This model describes full-length from some species, and the C-terminal region only from other species, of the YidC/Oxa1 family of proteins. This domain appears to be univeral among bacteria (although absent from Archaea). The well-characterized YidC protein from Escherichia coli and its close homologs contain a large N-terminal periplasmic domain in addition to the region modeled here. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 274665 [Multi-domain] Cd Length: 179 Bit Score: 224.28 E-value: 2.08e-74
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446843294 60 SFGIAIIIMTLVIRSAMIPLAVSQYRSQAKMKKMQPELQKLKKKYGDvskdlEKQKQyQKEMSELMKSGGWNPLAGCWPI 139
Cdd:TIGR03592 1 NWGLAIILLTIIVRLILLPLTLKQYKSMRKMQELQPKLKEIQEKYKE-----DPQKL-QQEMMKLYKEEGVNPLGGCLPL 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446843294 140 FIQMPIFSALYYAISRTEEIRTSSFLWV-NLGHADPYHILPIIAALTTFIQMKVfqsNITAGEQVQMLKMQQIMMPAMIL 218
Cdd:TIGR03592 75 LIQMPIFIALYQVLLRSIELRHAPFLWIiDLSSPDPYYILPILMGVTMFLQQKL---SPKGPPDPAQQKMMMYFMPLMFL 151
|
170 180
....*....|....*....|....*...
gi 446843294 219 FMGFAAPSGLVLYWITGNLFTMTQTIVL 246
Cdd:TIGR03592 152 FFFLSFPAGLVLYWVVSNLFTIIQQLII 179
|
|
| 5TM_YidC_Alb3 |
cd20070 |
Five transmembrane core domain of membrane protein insertase YidC, Alb3, and similar proteins; ... |
62-248 |
1.08e-71 |
|
Five transmembrane core domain of membrane protein insertase YidC, Alb3, and similar proteins; This group is composed of the bacterial and chloroplastic members of the YidC/Oxa1/Alb3 protein family of insertases, including bacterial YidC, and chloroplastic ALBINO3 (Alb3) and Alb3-like proteins such as ALBINO3-like protein 1 (also called Alb4). Membrane protein insertase YidC, also called foldase YidC or membrane integrase YidC, facilitates proper folding, insertion, and assembly of inner membrane proteins and complexes. Depending on the nature of the substrate, YidC functions in a Sec-independent (YidC only) or a Sec-dependent manner as part of a complex containing YidC, the SecYEG channel, and SecDFYajC. YidC from Gram-negative bacteria contains an extra transmembrane segment (TM1) at the N-terminus and a large periplasmic domain, located between TM1 and TM2, that adopts a beta-super sandwich fold that is found in sugar-binding proteins such as galactose mutarotase. Alb3 and Alb3-like proteins are required for the post-translational insertion of the light-harvesting chlorophyll-binding proteins (LHCPs) into the chloroplast thylakoid membrane. Alb3 acts independently and may also function cooperatively with the thylakoid cpSecYE translocase to insert proteins co-translationally into the thylakoid membrane, similar to bacterial YidC that can function with the SecYEG translocase. YidC/Oxa1/Alb3 family insertases contain a core domain of five transmembrane (5TM) segments that is essential to insertase function.
Pssm-ID: 410994 [Multi-domain] Cd Length: 181 Bit Score: 217.63 E-value: 1.08e-71
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446843294 62 GIAIIIMTLVIRSAMIPLAVSQYRSQAKMKKMQPELQKLKKKYGDvskdlEKQKQyQKEMSELMKSGGWNPLAGCWPIFI 141
Cdd:cd20070 1 GLAIILLTILIRLLLLPLTLKQYKSMKKMQELQPKIKEIQEKYKD-----DKQKL-QQEMMKLYKEHGVNPLGGCLPLLI 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446843294 142 QMPIFSALYYAISRTEEIRTSSFLWV--NLGHADPYHILPIIAALTTFIQMKVfqSNITAGEQVQMLKMQQIMMPAMILF 219
Cdd:cd20070 75 QMPIFIALYQVLRNSIELRGAPFLWWilDLSAPDPYYILPILMGVTMFLQQKL--TPTPTDDQAPQQKMMMYFMPVMFTF 152
|
170 180
....*....|....*....|....*....
gi 446843294 220 MGFAAPSGLVLYWITGNLFTMTQTIVLRR 248
Cdd:cd20070 153 IFLSFPSGLVLYWLVSNLFSIIQQLIINK 181
|
|
| PRK02944 |
PRK02944 |
YidC family membrane integrase SpoIIIJ; |
22-247 |
1.56e-70 |
|
YidC family membrane integrase SpoIIIJ;
Pssm-ID: 179508 Cd Length: 255 Bit Score: 217.33 E-value: 1.56e-70
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446843294 22 GCSNA-APIDAHSTGIWDHYFVYPISFMIQFVAHhIPGASFGIAIIIMTLVIRSAMIPLAVSQYRSQAKMKKMQPELQKL 100
Cdd:PRK02944 20 GCSEVnQPITPKSTGFWNEYFVYPLSQLITYFAN-LFGSNYGLAIIVVTLLIRLLILPLMIKQTKSTKAMQALQPEMQKL 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446843294 101 KKKYGdvSKDLEKQKQYQKEMSELMKSGGWNPLAGCWPIFIQMPIFSALYYAISRTEEIRTSSFLWVNLGHADPYHILPI 180
Cdd:PRK02944 99 KEKYS--SKDQATQQKLQQEMMQLFQKNGVNPLAGCLPIFIQMPILIAFYHAIMRTSEISKHSFLWFDLGQADPYYILPI 176
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446843294 181 IAALTTFIQMKVFQSNiTAGEQVQMlKMQQIMMPAMILFMGFAAPSGLVLYWITGNLFTMTQTIVLR 247
Cdd:PRK02944 177 VAGITTFIQQKLMMAG-TAGQNPQM-AMMLWLMPIMILIFAINFPAALSLYWVVGNIFMIAQTYLIK 241
|
|
| 60KD_IMP |
pfam02096 |
60Kd inner membrane protein; |
61-248 |
2.53e-68 |
|
60Kd inner membrane protein;
Pssm-ID: 460443 [Multi-domain] Cd Length: 187 Bit Score: 209.25 E-value: 2.53e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446843294 61 FGIAIIIMTLVIRSAMIPLAVSQYRSQAKMKKMQPELQKLKKKYGDvskdlEKQKQyQKEMSELMKSGGWNPLAGCWPIF 140
Cdd:pfam02096 1 YGLAIILLTILIKLILFPLTYKQYKSMAKMQELQPEMKEIQEKYKD-----DRQKL-QQEMMKLYKKEGVNPLGGCLPML 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446843294 141 IQMPIFSALYYAISRTEEIR-TSSFLWV-NLGHADP-----YHILPIIAALTTFIQMKvfQSNITAGEQVQMLKMQQIMM 213
Cdd:pfam02096 75 IQMPIFIALYRVLRNSIELRhAPFFLWIaDLSAPDPisilhYYILPILMGVTMFLQQK--LTPAPQDQPPQMKMMMLYFM 152
|
170 180 190
....*....|....*....|....*....|....*
gi 446843294 214 PAMILFMGFAAPSGLVLYWITGNLFTMTQTIVLRR 248
Cdd:pfam02096 153 PLMFLFFFLNFPAGLVLYWVVSNLLSIGQQLIINR 187
|
|
| PRK01318 |
PRK01318 |
membrane protein insertase; Provisional |
37-255 |
1.67e-61 |
|
membrane protein insertase; Provisional
Pssm-ID: 234942 [Multi-domain] Cd Length: 521 Bit Score: 201.64 E-value: 1.67e-61
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446843294 37 WDHYFVYPISFMIQFVAHHIPgaSFGIAIIIMTLVIRSAMIPLAVSQYRSQAKMKKMQPELQKLKKKYGDvskdlEKQKQ 116
Cdd:PRK01318 301 WLWFITKPLFWLLDFLHSFVG--NWGWAIILLTIIVKLLLFPLTYKSYVSMAKMKVLQPKMQELKEKYKD-----DPQKM 373
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446843294 117 yQKEMSELMKSGGWNPLAGCWPIFIQMPIFSALYYAISRTEEIRTSSF-LWVN-LGHADPYHIL-----PIIAALTTFIQ 189
Cdd:PRK01318 374 -QQEMMELYKKEKVNPLGGCLPILIQIPIFFALYKVLLVSIELRHAPFiGWIHdLSAPDPYFILhigllPILMGITMFLQ 452
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446843294 190 MKVfqsNITAGEQVQMLKMQqiMMPAMILFMGFAAPSGLVLYWITGNLFTMTQTIVLRRIMEREEL 255
Cdd:PRK01318 453 QKL---NPTPTDPMQAKIMK--FMPLIFTFFFLSFPAGLVLYWIVNNLLTIIQQYLINRRLEKKKL 513
|
|
| PRK00145 |
PRK00145 |
putative inner membrane protein translocase component YidC; Provisional |
41-260 |
8.57e-51 |
|
putative inner membrane protein translocase component YidC; Provisional
Pssm-ID: 234665 [Multi-domain] Cd Length: 223 Bit Score: 165.68 E-value: 8.57e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446843294 41 FVYPISFMIQFVAHHI--PGASFGIAIIIMTLVIRSAMIPLAVSQYRSQAKMKKMQPELQKLKKKYgdvSKDLEKQKQyq 118
Cdd:PRK00145 9 FVQFFKFIHGFVSSVIsnPNFSYGIAIILVTLIIRLLILPLNIKQTKSSLRMNEIQPEIKKLQAKY---KNDPQKLQQ-- 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446843294 119 kEMSELMKSGGWNPLAGCWPIFIQMPIFSALYYAISRTEEIRTSSFLWV-NLGHADPYHILPIIAALTTFIQmKVFQSNI 197
Cdd:PRK00145 84 -EMMKLYKEKGVNPLGGCLPLLIQWPILIALYYVFNNLTGINGVSFLWIkDLAKPDITWILPILSGATTYLS-GYLMTKA 161
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446843294 198 TAGEQVQMlKMQQIMMPAMILFMGFAAPSGLVLYWITGNLFTMTQTIVLRRIMEREELQLQKA 260
Cdd:PRK00145 162 DSSQAGQM-KTMNIGMSIFMGVMSWKFKSALVLYWVIGNLIQIIQTYFIKKLELKKKVEAKAA 223
|
|
| 5TM_YidC_Oxa1_Alb3 |
cd19751 |
Five transmembrane core domain of YidC/Oxa1/Alb3 protein family of insertases; The YidC/Oxa1 ... |
62-248 |
1.14e-49 |
|
Five transmembrane core domain of YidC/Oxa1/Alb3 protein family of insertases; The YidC/Oxa1/Alb3 protein family of insertases facilitate the insertion, folding and assembly of proteins of the inner membranes of bacteria and mitochondria, and the thylakoid membrane of plastids. Members include bacterial YidC, mitochondrial Cox18 and Oxa1, and chloroplastic Alb3 and Alb4. Membrane protein insertase YidC, also called foldase YidC or membrane integrase YidC, facilitates proper folding, insertion, and assembly of inner membrane proteins and complexes. Oxa1 and Cox18/Oxa2 mediate the insertion of both mitochondrion-encoded precursors and nuclear-encoded proteins from the matrix into the mitochondrial inner membrane. Alb3 and Alb3-like proteins, including Alb4, are required for the post-translational insertion of the light-harvesting chlorophyll-binding proteins (LHCPs) into the chloroplast thylakoid membrane. YidC/Oxa1/Alb3 family insertases contain a core domain of five transmembrane (5TM) segments that is essential to insertase function.
Pssm-ID: 410992 [Multi-domain] Cd Length: 189 Bit Score: 161.57 E-value: 1.14e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446843294 62 GIAIIIMTLVIRSAMIPLAVSQYRSQAKMKKMQPELQKLKKKYGDVSKDLEKQKQYQKEMSELMKSGGWNPLAGCWPIFI 141
Cdd:cd19751 1 GLSIIIVTILIRLALLPLTLKQQKSMRKMQVIRPEMEAIREKYKEKASKDKVQQEMQKEMLGLYKKHGVNPMAGCLPLFI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446843294 142 QMPIFSALYYAISRTEEIRTSSFLWV-NLGHADPYHILPIIAALTTFIQMKVFQSNITAGEQVQMLkMQQIM--MPAMIL 218
Cdd:cd19751 81 QLPIFMAFYFAIMRTEEIRYHTFLWFfDLGQPDYLYILPFVAGITTYFQFKMTMSHQQQMQMMQMQ-MKVMLyvMPVMII 159
|
170 180 190
....*....|....*....|....*....|
gi 446843294 219 FMGFAAPSGLVLYWITGNLFTMTQTIVLRR 248
Cdd:cd19751 160 IAGLSFPSALSLYWIISNLFMIIQTYFIVR 189
|
|
| PRK02463 |
PRK02463 |
OxaA-like protein precursor; Provisional |
32-250 |
1.16e-41 |
|
OxaA-like protein precursor; Provisional
Pssm-ID: 235040 Cd Length: 307 Bit Score: 144.49 E-value: 1.16e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446843294 32 HSTGIWDHYFVYPISFMIQFVAHHIpGASFGIAIIIMTLVIRSAMIPLAVSQYRS----QAKMKKMQPELQKLKKKYGDV 107
Cdd:PRK02463 32 NPTGFIWNFLGAPMSYFIDYFANNL-GLGFGLAIIIVTIIVRLIILPLGLYQSWKatyqSEKMAYLKPVFEPINERLKNA 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446843294 108 SKDLEKQkQYQKEMSELMKSGGWNPLA--GCWPIFIQMPIFSALYYAISRTEEIRTSSFLWVNLGHadPYHILPIIAALT 185
Cdd:PRK02463 111 TTQEEKM-AAQTELMAAQRENGISMLGgiGCLPLLIQMPFFSALYFAAQYTKGVSTSTFLGIDLGS--PSLVLTAIIGVL 187
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446843294 186 TFIQMKVFQSNITAGEQVQMLKMqQIMMPAMILFMGFAAPSGLVLYWITGNLFTMTQTIVLRRIM 250
Cdd:PRK02463 188 YFFQSWLSMMGVPEEQREQMKAM-MYMMPIMMVVFSFSSPAGVGLYWLVGGFFSIIQQLITTYIL 251
|
|
| 5TM_Oxa1-like |
cd20069 |
Five transmembrane core domain of mitochondrial inner membrane protein Oxa1 and similar ... |
64-247 |
1.00e-39 |
|
Five transmembrane core domain of mitochondrial inner membrane protein Oxa1 and similar proteins; This group is composed mostly of the mitochondrial members of the YidC/Oxa1/Alb3 protein family of insertases, including mitochondrial inner membrane proteins Oxa1, Oxa1-like (Oxa1L), cytochrome c oxidase assembly protein 18 (Cox18, also called Oxa2), and Arabidopsis thaliana mitochondrial ALBINO3-like protein 3 (ALB33). It also includes Arabidopsis thaliana chloroplastic ALBINO3-like protein 2 (ALB32). Members of this group mediate the insertion of both mitochondrion-encoded precursors and nuclear-encoded proteins from the matrix into the mitochondrial inner membrane. Oxa1 and Cox18/Oxa2 are essential for the activity and assembly of cytochrome c oxidase, playing central roles in the translocation and export of the N-terminal and C-terminal parts, respectively, of the COX2 protein into the mitochondrial intermembrane space. ALB32 may be involved in the insertion of integral membrane proteins into the chloroplast thylakoid membranes. YidC/Oxa1/Alb3 family insertases contain a core domain of five transmembrane (5TM) segments that is essential to insertase function.
Pssm-ID: 410993 [Multi-domain] Cd Length: 201 Bit Score: 136.50 E-value: 1.00e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446843294 64 AIIIMTLVIRSAMIPLAVSQYRSQAKMKKMQPELQKLKKKYGD--VSKDLEKQKQYQKEMSELMKSGGWNPLAGCWPIFI 141
Cdd:cd20069 7 TIAATTVALRLLLLPLVIKSQRNAARMANLQPELQKLQEKLKEarASGDQLEAAEARKELKELMKKHNVNPLKSLLLPLV 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446843294 142 QMPIFSALYYAISR-----TEEIRTSSFLWV-NLGHADPYHILPIIAALTTFIQMKVFQSNITAGEQvQMLKMQQIM--M 213
Cdd:cd20069 87 QAPVFISFFFALRKmanlpVPSFKTGGLLWFtDLTVPDPYYILPILTSLTFLATIELGAETGTSGSP-QSKTMKNVFrgL 165
|
170 180 190
....*....|....*....|....*....|....
gi 446843294 214 PAMILFMGFAAPSGLVLYWITGNLFTMTQTIVLR 247
Cdd:cd20069 166 PVLMIPFTANFPSAVFLYWITSNLFSLAQNLLLR 199
|
|
| PRK01315 |
PRK01315 |
putative inner membrane protein translocase component YidC; Provisional |
58-248 |
1.13e-34 |
|
putative inner membrane protein translocase component YidC; Provisional
Pssm-ID: 234941 Cd Length: 329 Bit Score: 126.78 E-value: 1.13e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446843294 58 GASFGIAIIIMTLVIRSAMIPLAVSQYRSQAKMKKMQPELQKLKKKYGDvskDLEKQKQyqkEMSELMKSGGWNPLAGCW 137
Cdd:PRK01315 39 GLTWVLSIVGLVIVIRALLIPLFVKQIKSQRNMQEIQPKMKKIQEKYKG---DRERMSQ---EMMKLYKETGTNPLSSCL 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446843294 138 PIFIQMPIFSALYYAISRTEEIRT-----SSFLWVNLGHAD----PYH-------------------ILPIIAALTTFI- 188
Cdd:PRK01315 113 PLLLQMPIFFALYRVLDSAASRGDgigpiNPPLLESFRHAHifgaPLAatflqalnagntavqvvaaVLIILMSASQFIt 192
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446843294 189 QMKVFQSNIT-AGEQVQMLKMQQIMM---PAMILFMGFAAPSGLVLYWITGNLFTMTQTIVLRR 248
Cdd:PRK01315 193 QLQLMTKNMPpEAKTGPMAQQQKMLLylfPLMFLVSGIAFPVGVLFYWLTSNVWTMGQQFYVIR 256
|
|
| PRK01001 |
PRK01001 |
putative inner membrane protein translocase component YidC; Provisional |
47-258 |
9.84e-28 |
|
putative inner membrane protein translocase component YidC; Provisional
Pssm-ID: 234887 [Multi-domain] Cd Length: 795 Bit Score: 111.43 E-value: 9.84e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446843294 47 FMIQFVAHHIPGaSFGIAIIIMTLVIRSAMIPLAVSQYRSQAKMKKMQPELQKLKKKYgdvSKDlekQKQYQKEMSELMK 126
Cdd:PRK01001 563 FIIMKFFKFLTG-SWGISIILLTVFLKLLLYPLNAWSIRSMRRMQKLSPYIQEIQQKY---KKE---PKRAQMEIMALYK 635
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446843294 127 SGGWNPLAGCWPIFIQMPIFSALYYAISRTEEIRTSSFL--WV-NLGHAD--------------PYHILPIIAALTTFIQ 189
Cdd:PRK01001 636 TNKVNPITGCLPLLIQLPFLIAMFDLLKSSFLLRGASFIpgWIdNLTAPDvlfswetpiwfignEFHLLPILLGVVMFAQ 715
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446843294 190 MKvFQSNITAGEQVQMLKMQQI---MMPAMILFMGFAAPSGLVLYWITGNLFTMTQTIVLRRIMEREELQLQ 258
Cdd:PRK01001 716 QK-ISSLKRKGPVTDQQRQQEAmgtMMALLFTFMFYNFPSGLNIYWLSSMLLGVIQQWVTNKILDSKHLKNE 786
|
|
| PRK03449 |
PRK03449 |
putative inner membrane protein translocase component YidC; Provisional |
43-254 |
1.13e-27 |
|
putative inner membrane protein translocase component YidC; Provisional
Pssm-ID: 179580 Cd Length: 304 Bit Score: 107.84 E-value: 1.13e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446843294 43 YPISFmIQFVAHHI------PGASFGIAIIIMTLV--IRSAMIPLAVSQYRSQAKMKKMQPELQKLKKKYGDvskdlEKQ 114
Cdd:PRK03449 7 YPVSA-ILWFWHKLfsfvlgPDNGFAWALSVMFLVftLRALLYKPFVRQIRTTRKMQELQPQIKALQKKYGN-----DRQ 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446843294 115 KQYQkEMSELMKSGGWNPLAGCWPIFIQMPIFSALYYAI---SRT-----------EEIRTS-----------SFLWVNL 169
Cdd:PRK03449 81 KMAL-EMQKLQKEHGFNPILGCLPMLAQIPVFLGLFHVLrsfNRTgtgfgqlgmsvEENRNTpnyvfsaedvqSFLDARL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446843294 170 GHA--DPYHILP-----------------------IIAALTTFI--QMKVFQSNITAGEQVQMLKMQQIM---MPAMILF 219
Cdd:PRK03449 160 FGAplSAYITMPrsgldafvdftrtniilvgvplmIIAGVATHFnsRASVARQSAEAAANPQTAMMNKLAlwvFPLGVLV 239
|
250 260 270
....*....|....*....|....*....|....*
gi 446843294 220 MGFAAPSGLVLYWITGNLFTMTQTIVLRRIMEREE 254
Cdd:PRK03449 240 GGPFLPLAILLYWVSNNIWTFGQQHYVFGKIDKEE 274
|
|
| PRK02201 |
PRK02201 |
putative inner membrane protein translocase component YidC; Provisional |
41-244 |
7.77e-26 |
|
putative inner membrane protein translocase component YidC; Provisional
Pssm-ID: 235012 Cd Length: 357 Bit Score: 103.94 E-value: 7.77e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446843294 41 FVYPISFMIQFVAHHIPGASFG-----IAIIIMTLVIRSAMIPLAVSQYRSQAKMKKMQPELQKLKKKYGDVSKDLEKQK 115
Cdd:PRK02201 108 FVYPIAQIILSIMASQSLSELYgwstiLAIIVVVLIIRLISFLITFKSTFNQEKQEELQGKKAKIDAKYKDYKKDKQMKQ 187
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446843294 116 QYQKEMSELMKSGGWNPLAGCWPIFIQMPIFSALYYAISRTEEIRTSSFLWVNLGHAD---------PYHILPIIAALTT 186
Cdd:PRK02201 188 RKQQEIQELYKKHNISPFSPFVQMFVTLPIFIAVYRVVQSLPSIKVTTWLGIDLSATSwqeifagnwIYLPILIIVVPVQ 267
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446843294 187 FIQMKVFQ-------SNITAGEQVQ-----MLKMQQIMmpaMILFMGFAA--PSGLVLYWITGNLFTMTQTI 244
Cdd:PRK02201 268 ALSQLLPQilnkkknKERTLNVKEKealkkQNKTQNII---SIVFIFFGVifAAGVQIYWIIGGIWTILQTL 336
|
|
| PRK02654 |
PRK02654 |
putative inner membrane protein translocase component YidC; Provisional |
60-150 |
1.96e-23 |
|
putative inner membrane protein translocase component YidC; Provisional
Pssm-ID: 235058 Cd Length: 375 Bit Score: 97.36 E-value: 1.96e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446843294 60 SFGIAIIIMTLVIRSAMIPLAVSQYRSQAKMKKMQPELQK----LKKKYGDvskdlEKQKQyQKEMSELMKSGGwNPLAG 135
Cdd:PRK02654 26 SYGLAIVALTLVIRFALYPLSAGSIRNMRRMKIAQPVMQKrqaeIQERYKN-----DPQKQ-QEEMGKLMKEFG-NPLAG 98
|
90
....*....|....*
gi 446843294 136 CWPIFIQMPIFSALY 150
Cdd:PRK02654 99 CLPLLVQMPILFALF 113
|
|
| PRK00247 |
PRK00247 |
putative inner membrane protein translocase component YidC; Validated |
41-252 |
3.56e-20 |
|
putative inner membrane protein translocase component YidC; Validated
Pssm-ID: 178945 [Multi-domain] Cd Length: 429 Bit Score: 88.75 E-value: 3.56e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446843294 41 FVYPISFMIQ---FVAHHIPGASFGIAIII----MTLVIRSAMIPLAVSQYRSQAKMKKMQPELQKLKKKYGDvSKDLEK 113
Cdd:PRK00247 5 FIYPVSGVMKlwhLLLHNVLGLDDSLAWFAslfgLVITVRAIIAPFTWQQYKSGRTAAHIRPKRKALREEYKG-KTDEAS 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446843294 114 QKQYQKEMSELMKSGGWNPLAGCWPIFIQMPIFSALYYAISR--------------------TEEIRtsSFL-------- 165
Cdd:PRK00247 84 IRELQQKQKDLNKEYGYNPLAGCVPALIQIPVFLGLYQVLLRmarpegglenpvhqpigfltSEEVE--SFLqgrvfnvp 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446843294 166 -------------WVNLGHADPYH-ILP--IIAALTTFIQMKV-----FQSNITAGE-QVQMLKM---QQIMMPAMILFM 220
Cdd:PRK00247 162 lpayvsmpaeqlaYLGTTQATVLAfVLPlfIAAAVFTAINMAMstyrsFQTNDHDSGfAVGMLKFlivMAILAPIFPLSL 241
|
250 260 270
....*....|....*....|....*....|....
gi 446843294 221 GFAA--PSGLVLYWITGNLFTMTQTIVLRRIMER 252
Cdd:PRK00247 242 GLTGpfPTAIALYWVANNLWTLIQNIIMYLILER 275
|
|
| |
