|
Name |
Accession |
Description |
Interval |
E-value |
| PRK10600 |
PRK10600 |
nitrate/nitrite two-component system sensor histidine kinase NarX; |
30-598 |
0e+00 |
|
nitrate/nitrite two-component system sensor histidine kinase NarX;
Pssm-ID: 182581 [Multi-domain] Cd Length: 569 Bit Score: 1100.11 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446840827 30 MAVSGWLVQGVQGSAHAINKAGSLRMQSYRLLAAVPLSEKDKPLIKEMEQTAFSAELTRAAERDGQLAQLQGLQDYWRNE 109
Cdd:PRK10600 1 MAVSGWLVQGVQGSAHAINKAGSLRMQSYRLLAAVPLSEKDKPLLKEMEQTAFSPELQRAAERDGQLAQLQALQDYWRNE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446840827 110 LIPTLMRAQNRETVSADVSQFVAGLDQLVSGFDRTTEMRIETVVLVHRVMAVFMALLLVFTIIWLRARLLQPWRQLLAMA 189
Cdd:PRK10600 81 LKPALQQAQNPEDVAADVAQFVAGLDALVSAFDHTTEMRIETVVLVHRVFAVFMALLLVFTIIWLRRRLLQPWRQLLSMA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446840827 190 SAVSHRDFTQRANISGRNEMAMLGTALNNMSAELAESYAVLEQRVQEKTAGLEHKNQILSFLWQANRRLHSRAPLCERLS 269
Cdd:PRK10600 161 NAVSHRDFTQRANISGRDEMAMLGTALNNMSAELAESYAVLEQRVQEKTAGLEQKNQILSFLWQANRRLHSRAPLCERLS 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446840827 270 PVLNGLQNLTLLRDIELRVYDTDDEENHQEFTCQPDMTCDDKGCQLCPRGVLPVGDRGTTLKWRLADSHTQYGILLATLP 349
Cdd:PRK10600 241 PVLNGLQNLTLLRDIELRVYETDDEENHQEFTCQSDMTCDDKGCQLCPRGVLPVGDRGTTLKWRLSDKHGQYGILLATLP 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446840827 350 QGRHLSHDQQQLVDTLVEQLTATLALDRHQERQQQLIVMEERATIARELHDSIAQSLSCMKMQVSCLQMQGDALPESSRE 429
Cdd:PRK10600 321 QGRHLSHDQQQLVDTLVEQLTATLALERQQERQQQLIVMEERATIARELHDSIAQSLSCMKMQVSCLQMQGDALPESSRE 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446840827 430 LLSQIRNELNASWAQLRELLTTFRLQLTEPGLRPALEASCEEYSAKFGFPVKLDYQLPPRLVPSHQAIHLLQIAREALSN 509
Cdd:PRK10600 401 LLSQIRNELNASWRQLRELLTTFRLQLTEPGLRPALEASCEEFSARFGFPVKLDYQLPPRLVPSHQAIHLLQIAREALSN 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446840827 510 ALKHSQASEVVVTVAQNDNQVKLTVQDNGCGVPENAIRSNHYGMIIMRDRAQSLRGDCRVRRRESGGTEVVVTFIPEKTF 589
Cdd:PRK10600 481 ALKHAQASEVVVTVAQNQNQVKLSVQDNGCGVPENAERSNHYGLIIMRDRAQSLRGDCRVRRRESGGTEVVVTFIPEKTF 560
|
....*....
gi 446840827 590 TDVQGDTHE 598
Cdd:PRK10600 561 TDVQGDTHE 569
|
|
| PRK10935 |
PRK10935 |
nitrate/nitrite two-component system sensor histidine kinase NarQ; |
17-588 |
3.11e-101 |
|
nitrate/nitrite two-component system sensor histidine kinase NarQ;
Pssm-ID: 236800 [Multi-domain] Cd Length: 565 Bit Score: 318.34 E-value: 3.11e-101
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446840827 17 LIVLLS---TAIGLAGMAVSgwlvqgvQGSAHAINKAGSLRMQSYRLL-----AAVPLSEKdkplIKEMEQTAFSAELTR 88
Cdd:PRK10935 17 LIILLSsltTGFALLTLASS-------LRDAEAINIAGSLRMQSYRLAydlqsGSPQLNAH----LREFEQSLHSPALKN 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446840827 89 -------AAERDgqlaQLQGLQDYWrnELIPTLMRAQNRETVSADVSQFVAGLDQLVSGFDRTTEMRIETVVLVHRVMAV 161
Cdd:PRK10935 86 lnrwyvpEDVKD----RYALLIARW--LEMKSYLEQGDSRWYQANIANYVDQIDLFVLALQHFAERKLILLAAISLLGLI 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446840827 162 FMALLLVFTIIWLRARLLQPWRQLLAMASAVSHRDF-TQRANISGRNEMAMLGTALNNMSAELAESYAVLEQRVQEKTAG 240
Cdd:PRK10935 160 LILTLVFFTVRFTRRQVVAPLNQLVTASQQIEKGQFdHIPLDTTLPNELGLLAKAFNQMSSELHKLYRSLEASVEEKTRK 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446840827 241 LEHKNQILSFLWQANRRLHSRAPLCERLSPVLNGLQNLTLLRDIELRVYDtDDEENHQEFTcqpdmTCDDKGCQLCPrgv 320
Cdd:PRK10935 240 LTQANRSLEVLYQCSQALNASQIDVHCFRHILQIVRDHEGLDYLELEVGE-NEHWRISEGQ-----PNPELPWQILP--- 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446840827 321 lpvgdrgttlkwrLADSHTQYGILL--ATLPqgrhlsHDQQQLVDTLVEQLTATLALDRHQERQQQLIVMEERATIAREL 398
Cdd:PRK10935 311 -------------LTMEDTVLGYLHwqASLP------CPDEPLMNNVAQMLGRGLYFNQAQKQQQQLLLMEERATIAREL 371
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446840827 399 HDSIAQSLSCMKMQVSCLQMQGDALPESSRELLSQIRNELNASWAQLRELLTTFRLQLTEPGLRPALEASCEEYSAKFGF 478
Cdd:PRK10935 372 HDSLAQVLSYLKIQLTLLKRSLDEDNAKAQSIIAEFDQALSDAYRQLRELLTTFRLTIQEANLGSALEEMLDQLRNQTDA 451
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446840827 479 PVKLDYQLPPRLVPSHQAIHLLQIAREALSNALKHSQASEVVVTVAQN-DNQVKLTVQDNGCGVPENAIRSNHYGMIIMR 557
Cdd:PRK10935 452 KITLDCRLPSQALDAQQQVHLLQIIREATLNAIKHANASEIAVSCVTNpDGEHTVSIRDDGIGIGELKEPEGHYGLNIMQ 531
|
570 580 590
....*....|....*....|....*....|.
gi 446840827 558 DRAQSLRGDCRVRRRESGGTEVVVTFIPEKT 588
Cdd:PRK10935 532 ERAERLGGTLTISQPPGGGTTVSLTFPSQQE 562
|
|
| NarX_sensor |
cd22900 |
ligand binding sensor domain of NarX, and related chemoreceptors; The periplasmic ligand ... |
38-152 |
7.37e-57 |
|
ligand binding sensor domain of NarX, and related chemoreceptors; The periplasmic ligand binding sensor domain of NarX is a histidine kinase receptor that responds to nitrate and nitrite to effect regulation of anaerobic respiration in various bacteria and similar proteins. It forms a homodimer and binds to ligands such as nitrate via the dimerization interface, a feature that appears to be conserved in this domain superfamily. NarX-NarL sensor-response regulator pair controls Escherichia coli gene expression in response to nitrate and nitrite. NarX has been shown to exhibit a clear kinetic preference for NarL over NarP, the sensor response partner of NarQ.
Pssm-ID: 438632 [Multi-domain] Cd Length: 116 Bit Score: 187.00 E-value: 7.37e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446840827 38 QGVQGSAHAINKAGSLRMQSYRLLAAVPLSEKDKPLIKEMEQTAFSAELTRAAERDGQLAQLQGLQDYWRNELIPTLMRA 117
Cdd:cd22900 1 NSIQGNAHAINKAGSLRMQSYRLLAAVPLNPQDQALLDELEQTLSSPELQRAARREGLQSQLQALQQYWQQQLKPALLAA 80
|
90 100 110
....*....|....*....|....*....|....*
gi 446840827 118 QNRETVSADVSQFVAGLDQLVSGFDRTTEMRIETV 152
Cdd:cd22900 81 KNPEDARAEVAAFVAQLDQLVSQIDQKTEQRLSLI 115
|
|
| ComP |
COG4585 |
Signal transduction histidine kinase ComP [Signal transduction mechanisms]; |
361-583 |
4.09e-55 |
|
Signal transduction histidine kinase ComP [Signal transduction mechanisms];
Pssm-ID: 443642 [Multi-domain] Cd Length: 252 Bit Score: 187.13 E-value: 4.09e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446840827 361 LVDTLVEQLTATLALDRHQERQQQLIVMEERATIARELHDSIAQSLSCMKMQVSCLQMQGDALPESSRELLSQIRNELNA 440
Cdd:COG4585 24 LVLLRARRAERAAELERELAARAEEAREEERRRIARELHDGVGQSLSAIKLQLEAARRLLDADPEAAREELEEIRELARE 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446840827 441 SWAQLRELLTTFR-LQLTEPGLRPALEASCEEYSAKFGFPVKLDYQLPPRLVPSHQAIHLLQIAREALSNALKHSQASEV 519
Cdd:COG4585 104 ALAELRRLVRGLRpPALDDLGLAAALEELAERLLRAAGIRVELDVDGDPDRLPPEVELALYRIVQEALTNALKHAGATRV 183
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446840827 520 VVTVAQNDNQVKLTVQDNGCGVPENAIRSNHYGMIIMRDRAQSLRGDCRVRRRESGGTEVVVTF 583
Cdd:COG4585 184 TVTLEVDDGELTLTVRDDGVGFDPEAAPGGGLGLRGMRERAEALGGTLTIGSAPGGGTRVRATL 247
|
|
| HATPase_UhpB-NarQ-NarX-like |
cd16917 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
499-583 |
7.60e-28 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli UhpB, NarQ and NarX, and Bacillus subtilis YdfH, YhcY and YfiJ; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs) such as Escherichia coli UhpB, a HK of the UhpB-UhpA TCS, NarQ and NarX, HKs of the NarQ-NarP and NarX-NarL TCSs, respectively, and Bacillus YdfH, YhcY and YfiJ HKs, of the YdfH-YdfI, YhcY-YhcZ and YfiJ-YfiK TCSs, respectively. In addition, it includes Bacillus YxjM, ComP, LiaS and DesK, HKs of the YxjM-YxjML, ComP-ComA, LiaS-LiaR, DesR-DesK TCSs, respectively. Proteins having this HATPase domain have a histidine kinase dimerization and phosphoacceptor domain; some have accessory domains such as GAF, HAMP, PAS and MASE sensor domains.
Pssm-ID: 340394 [Multi-domain] Cd Length: 87 Bit Score: 106.87 E-value: 7.60e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446840827 499 LLQIAREALSNALKHSQASEVVVTVAQNDNQVKLTVQDNGCG-VPENAIRSNHYGMIIMRDRAQSLRGDCRVRRRESGGT 577
Cdd:cd16917 1 LYRIVQEALTNALKHAGASRVRVTLSYTADELTLTVVDDGVGfDGPAPPGGGGFGLLGMRERAELLGGTLTIGSRPGGGT 80
|
....*.
gi 446840827 578 EVVVTF 583
Cdd:cd16917 81 RVTARL 86
|
|
| NarX_NarQ_sensor |
cd19408 |
ligand binding sensor domain of NarX and NarQ, and related chemoreceptors; The periplasmic ... |
41-151 |
5.03e-27 |
|
ligand binding sensor domain of NarX and NarQ, and related chemoreceptors; The periplasmic ligand binding sensor domain of NarX and NarQ is a histidine kinase receptor that responds to nitrate and nitrite to effect regulation of anaerobic respiration in various bacteria and similar proteins. It forms a homodimer and binds to ligands such as nitrate via the dimerization interface, a feature that appears to be conserved in this domain superfamily. NarX-NarL sensor-response regulator pair, along with NarQ-NarP, control Escherichia coli gene expression in response to nitrate and nitrite. NarX has been shown to exhibit a clear kinetic preference for NarL over NarP, whereas NarQ exhibits a relatively slight kinetic preference for NarL. There is asymmetry in the Nar cross-regulation network with NarQ shown to interact similarly with both response regulators, while NarX interacts preferentially with NarL.
Pssm-ID: 438626 [Multi-domain] Cd Length: 126 Bit Score: 105.79 E-value: 5.03e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446840827 41 QGSAHAINKAGSLRMQSYRLLAAVPLSEKDKP-----LIKEMEQTAFSAELTRAAERDGQ---LAQLQGLQDYWRNELIP 112
Cdd:cd19408 4 EGDAAAINLAGSLRMQSYRLASLLLQAALEPAeqlaqLIDEFEQRLNSPALTRALPRDSDhplRQAYQAVLQHWQQELRP 83
|
90 100 110 120
....*....|....*....|....*....|....*....|...
gi 446840827 113 TLMRA----QNRETVSADVSQFVAGLDQLVSGFDRTTEMRIET 151
Cdd:cd19408 84 ALEAAasgaADREAYLAEVDEFVAQIDQLVKLLQQDTEAKIRL 126
|
|
| UhpB |
COG3851 |
Signal transduction histidine kinase UhpB, glucose-6-phosphate specific [Signal transduction ... |
368-583 |
8.27e-26 |
|
Signal transduction histidine kinase UhpB, glucose-6-phosphate specific [Signal transduction mechanisms];
Pssm-ID: 443060 [Multi-domain] Cd Length: 493 Bit Score: 111.25 E-value: 8.27e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446840827 368 QLTATLALDRHQERQ--QQLIVMEE--RATIARELHDSIAQSLSCMKMQVSCLQMQGDAlpESSRELLSQIRNELNASWA 443
Cdd:COG3851 266 QLNQQLEQELRENRAlaRQLVSAEEseRREIARELHDEIGQNITAIRTQASILKRLAPQ--PEIEQSAQSIESLALRIYD 343
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446840827 444 QLRELLTTFR-LQLTEPGLRPALEASCEEYS-AKFGFPVKLDYQLPPRLVPSHQAIHLLQIAREALSNALKHSQASEVVV 521
Cdd:COG3851 344 TTRRLLDRLRpAVLDELGLEEALRELPRELAfEEPGISCQLDLRGDPSLLDDTLQLTLYRLVQEALTNILKHAEASQIRI 423
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446840827 522 TVAQNDNQVKLTVQDNGCGVPENAiRSNHYGMIIMRDRAQSLRGDCRVRRRESgGTEVVVTF 583
Cdd:COG3851 424 SLSQDKRLLSLEIRDDGIGLPPEL-RAKGFGLRGMRERVRALGGDFRLSSAPK-GTRLSVLL 483
|
|
| PRK11644 |
PRK11644 |
signal transduction histidine-protein kinase/phosphatase UhpB; |
365-582 |
7.18e-19 |
|
signal transduction histidine-protein kinase/phosphatase UhpB;
Pssm-ID: 236945 [Multi-domain] Cd Length: 495 Bit Score: 90.04 E-value: 7.18e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446840827 365 LVEQLTATLAldRHQERQQQLIVMEE--RATIARELHDSIAQSLSCMKMQVSCLQMQGDALPESSR-----ELLSqirne 437
Cdd:PRK11644 276 LNQSLQKELA--RNRHLAERLLETEEsvRRDVARELHDEIGQTITAIRTQAGIIKRLAADNASVKQsaqliEQLS----- 348
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446840827 438 LNAsWAQLRELLTTFR-LQLTEPGLRPALEASCEEYS-AKFGFPVKLDYQLPPRLVPSHQAIHLLQIAREALSNALKHSQ 515
Cdd:PRK11644 349 LGV-YDTVRRLLGRLRpRQLDDLTLEQAIRSLMREMElEDRGIVSHLDWRIDESALSETQRVTLFRVCQEGLNNIVKHAD 427
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446840827 516 ASEVVVTVAQNDNQVKLTVQDNGCGVPENAIrSNHYGMIIMRDRAQSLRGdcRVRRRESGGTEVVVT 582
Cdd:PRK11644 428 ASAVTLQGWQQDERLMLVIEDDGSGLPPGSG-QQGFGLRGMRERVTALGG--TLTISCTHGTRLSVS 491
|
|
| chemoreceptor_sensor |
cd00181 |
4-helix bundle ligand binding sensor domain of chemoreceptors such as Tar or Tsr; The ligand ... |
38-149 |
1.07e-18 |
|
4-helix bundle ligand binding sensor domain of chemoreceptors such as Tar or Tsr; The ligand binding sensor domain of chemoreceptors and related sensor histidine kinases forms homodimers and binds to ligands via the dimerization interface, a feature that appears to be conserved in this domain superfamily. This family includes ligand binding sensor domain of several chemoreceptors, such as Escherichia coli Tar, Tsr, NarQ, NarX, Pseudomonas aeruginosa KinB, Rhodopseudomonas palustris histidine kinase HK9 chemoreceptors, Comamonas testosteroni CNB-2 MCP2201 and Anaeromyxobacter dehalogenans histidine kinase Adeh_2942, among others.
Pssm-ID: 438624 [Multi-domain] Cd Length: 119 Bit Score: 82.18 E-value: 1.07e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446840827 38 QGVQGSAHAINKAGSLRMQSYRLLAAVPLS---EKDKPLIKEMEQTAFSAELTRAAERD------GQLAQLQGLQDYWRn 108
Cdd:cd00181 1 QEIRQQASAISSLESLVLQARVTLRAEALTgveELGDALIRALKQTAAVLAQFRALTRDppeaeaEILDKVQDYQKALA- 79
|
90 100 110 120
....*....|....*....|....*....|....*....|.
gi 446840827 109 ELIPTLMRaQNRETVSADVSQFVAGLDQLVSGFDRTTEMRI 149
Cdd:cd00181 80 ALIPALLE-RGAESALFDQSEAQGGLELLLSLLQQLTAAGI 119
|
|
| HATPase_c |
smart00387 |
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases. |
496-583 |
1.81e-16 |
|
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases.
Pssm-ID: 214643 [Multi-domain] Cd Length: 111 Bit Score: 75.38 E-value: 1.81e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446840827 496 AIHLLQIAREALSNALKHSQA-SEVVVTVAQNDNQVKLTVQDNGCGVPEN-----------------AIRSNHYGMIIMR 557
Cdd:smart00387 3 PDRLRQVLSNLLDNAIKYTPEgGRITVTLERDGDHVEITVEDNGPGIPPEdlekifepffrtdkrsrKIGGTGLGLSIVK 82
|
90 100
....*....|....*....|....*.
gi 446840827 558 DRAQSLRGDCRVRRRESGGTEVVVTF 583
Cdd:smart00387 83 KLVELHGGEISVESEPGGGTTFTITL 108
|
|
| HATPase_c |
pfam02518 |
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the ... |
496-583 |
1.88e-15 |
|
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the structurally related ATPase domains of histidine kinase, DNA gyrase B and HSP90.
Pssm-ID: 460579 [Multi-domain] Cd Length: 109 Bit Score: 72.40 E-value: 1.88e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446840827 496 AIHLLQIAREALSNALKHS-QASEVVVTVaQNDNQVKLTVQDNGCGVPENAI---------------RSNHYGMIIMRDR 559
Cdd:pfam02518 3 ELRLRQVLSNLLDNALKHAaKAGEITVTL-SEGGELTLTVEDNGIGIPPEDLprifepfstadkrggGGTGLGLSIVRKL 81
|
90 100
....*....|....*....|....
gi 446840827 560 AQSLRGDCRVRRRESGGTEVVVTF 583
Cdd:pfam02518 82 VELLGGTITVESEPGGGTTVTLTL 105
|
|
| HisKA_3 |
pfam07730 |
Histidine kinase; This is the dimerization and phosphoacceptor domain of a sub-family of ... |
390-453 |
3.21e-15 |
|
Histidine kinase; This is the dimerization and phosphoacceptor domain of a sub-family of histidine kinases. It shares sequence similarity with pfam00512 and pfam07536.
Pssm-ID: 429624 [Multi-domain] Cd Length: 68 Bit Score: 70.34 E-value: 3.21e-15
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446840827 390 ERATIARELHDSIAQSLSCMKMQVSCLQMQGDALPESSRELLSQIRNELNASWAQLRELLTTFR 453
Cdd:pfam07730 1 ERNRIARELHDSVGQSLTAIKLQLELARRLLDRDPEEAREQLDAIRELAREALQELRRLLGDLR 64
|
|
| NtrY |
COG5000 |
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism ... |
151-583 |
8.43e-15 |
|
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism regulation [Signal transduction mechanisms];
Pssm-ID: 444024 [Multi-domain] Cd Length: 422 Bit Score: 76.54 E-value: 8.43e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446840827 151 TVVLVHRVMAVFMALLLVFTIIWLRARLLQPWRQLLAMASAVSHRDFTQRANISGRNEMAMLGTALNNMSAELAESYAVL 230
Cdd:COG5000 6 LFLLLLLLIALLLLLLALWLALLLARRLTRPLRRLAEATRAVAAGDLSVRLPVTGDDEIGELARAFNRMTDQLKEQREEL 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446840827 231 EQRVQEKTAGLEHKNQ-ILSFlwQANRRLHSRAPLCERLSpvlnglqNLTLLRDIELRVYDTDDEENHQEFTCQPDMTCD 309
Cdd:COG5000 86 EERRRYLETILENLPAgVIVL--DADGRITLANPAAERLL-------GIPLEELIGKPLEELLPELDLAELLREALERGW 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446840827 310 DKGCQLCPRGVLPVGDRGTTLKWRladshtqyGILLatlpqgrhlshdqqqlvdtLVEQLTATLaldrhqeRQQQLIVME 389
Cdd:COG5000 157 QEEIELTRDGRRTLLVRASPLRDD--------GYVI-------------------VFDDITELL-------RAERLAAWG 202
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446840827 390 EratIAREL-HD------SIAQSLSCMKMQvscLQMQGDALPESSRELLSQIRNELNAswaqLRELLTTFR-------LQ 455
Cdd:COG5000 203 E---LARRIaHEiknpltPIQLSAERLRRK---LADKLEEDREDLERALDTIIRQVDR----LKRIVDEFLdfarlpePQ 272
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446840827 456 LTEPGLRPALEASCEEYSAKFGFP-VKLDYQLPPRLVPS-------HQAIH-LLQIAREALsnalkhSQASEVVVTVAQN 526
Cdd:COG5000 273 LEPVDLNELLREVLALYEPALKEKdIRLELDLDPDLPEVladrdqlEQVLInLLKNAIEAI------EEGGEIEVSTRRE 346
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446840827 527 DNQVKLTVQDNGCGVPEnAIRSN----HY---------GMIIMRDRAQSLRGDCRVRRRESGGTEVVVTF 583
Cdd:COG5000 347 DGRVRIEVSDNGPGIPE-EVLERifepFFttkpkgtglGLAIVKKIVEEHGGTIELESRPGGGTTFTIRL 415
|
|
| KdpD |
COG2205 |
K+-sensing histidine kinase KdpD [Signal transduction mechanisms]; |
374-583 |
2.43e-13 |
|
K+-sensing histidine kinase KdpD [Signal transduction mechanisms];
Pssm-ID: 441807 [Multi-domain] Cd Length: 239 Bit Score: 69.94 E-value: 2.43e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446840827 374 ALDRHQERQQQLIVMEER--ATIARELHdsiaQSLSCMKMQVSCLQMQGDALPESSRELLSQIRNELNaswaQLRELLTT 451
Cdd:COG2205 1 ELEEALEELEELERLKSEflANVSHELR----TPLTSILGAAELLLDEEDLSPEERRELLEIIRESAE----RLLRLIED 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446840827 452 F-----------RLQLTEPGLRPALEASCEEYSAKF-GFPVKLDYQLPPRLVPSHQAIHLL-QIAREALSNALKHSQA-S 517
Cdd:COG2205 73 LldlsrlesgklSLELEPVDLAELLEEAVEELRPLAeEKGIRLELDLPPELPLVYADPELLeQVLANLLDNAIKYSPPgG 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446840827 518 EVVVTVAQNDNQVKLTVQDNGCGVPENAI-----------RSNHY-----GMIIMRDRAQSLRGDCRVRRRESGGTEVVV 581
Cdd:COG2205 153 TITISARREGDGVRISVSDNGPGIPEEELeriferfyrgdNSRGEggtglGLAIVKRIVEAHGGTIWVESEPGGGTTFTV 232
|
..
gi 446840827 582 TF 583
Cdd:COG2205 233 TL 234
|
|
| COG3920 |
COG3920 |
Two-component sensor histidine kinase, HisKA and HATPase domains [Signal transduction ... |
84-583 |
4.34e-13 |
|
Two-component sensor histidine kinase, HisKA and HATPase domains [Signal transduction mechanisms];
Pssm-ID: 443125 [Multi-domain] Cd Length: 495 Bit Score: 71.86 E-value: 4.34e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446840827 84 AELTRAAERDGQLAQLQGLQDYWRNELIPTLMRAQNRETVSADVSQFVAGLDQLVSGFDRTTEMRIETVVLVHRVMAVFM 163
Cdd:COG3920 1 LLLALLLLLLLALAALLLLAALLLLAAALLLALLALLLLALLLLALLLASALLALLALSAAALAAALAVALAAAVGAAAA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446840827 164 ALLLVFTIIWLRARLLQPWRQLLAMASAVSHRDFTQRANISGRNEMAMLGTALNNMSAELAESYAVLEQRVQEKTAGLEH 243
Cdd:COG3920 81 LLALLVLLLLLLLAAAALALALLLAALAGLLLLAALLLLRLVALLAALALLALLLLLLLLLAILALAELAVALAELAAAL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446840827 244 KNQILSFLWQANRRLHSRAPLCERLSPVLNGLQNLTLLRDIELRVYDTDDEENHQEFTcqpdmtcddkgcqLCPRGVLPV 323
Cdd:COG3920 161 LLLAEELAALRLAAAALLLLLAALLDLGLALAALAAAALLALLLALELLLALLLLLLL-------------LLALLLVLL 227
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446840827 324 GDRGTTLKWRLADSHTQYGILLATLPQGRHLSHDQQQLVDTLVEQLTATLALDRHQERQQQLIVMEERATIARELHD--- 400
Cdd:COG3920 228 AALLRLRAAVLEELERRRRARGLGRLLLLLLLLLLLLRALLLLAAGIRLVITERKRAEEELEASLEEKELLLRELHHrvk 307
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446840827 401 ---SIAQSLscmkmqvscLQMQGDALP-ESSRELLSQIRNELNASwAQLRELLTTfRLQLTEPGLRPALEASCEEYSAKF 476
Cdd:COG3920 308 nnlQVVSSL---------LRLQARRADdPEAREALEESQNRIQAL-ALVHELLYQ-SEDWEGVDLRDYLRELLEPLRDSY 376
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446840827 477 G-FPVKLDYQLPPRLVPSHQAIHLLQIAREALSNALKHSQAS----EVVVTVAQNDNQVKLTVQDNGCGVPENAI--RSN 549
Cdd:COG3920 377 GgRGIRIELDGPDVELPADAAVPLGLILNELVTNALKHAFLSgeggRIRVSWRREDGRLRLTVSDNGVGLPEDVDppARK 456
|
490 500 510
....*....|....*....|....*....|....
gi 446840827 550 HYGMIIMRDRAQSLRGdcRVRRRESGGTEVVVTF 583
Cdd:COG3920 457 GLGLRLIRALVRQLGG--TLELDRPEGTRVRITF 488
|
|
| NarQ |
COG3850 |
Signal transduction histidine kinase NarQ, nitrate/nitrite-specific [Signal transduction ... |
41-400 |
1.08e-11 |
|
Signal transduction histidine kinase NarQ, nitrate/nitrite-specific [Signal transduction mechanisms];
Pssm-ID: 443059 [Multi-domain] Cd Length: 448 Bit Score: 67.22 E-value: 1.08e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446840827 41 QGSAHAINKAGSLRMQSYRLLAAVPLSEKDKPLIKEMEQTAFSAELTRAAERDGQLAQLQGLQDYWRNELIPTLMRAQNR 120
Cdd:COG3850 5 LLLALALLRLLLALLALLLLALLLLSLLALLLLLERTLLRLLSLLASAGLLAALLAALLLLLSLGLLALLLALLLLLLLL 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446840827 121 ETVSADVSQFVAGLDQLVSGFDRTTEMRIETVVLVHRVMAVFMALLLVFTIIWLRARLLQPWRQLLAMASAVSHRDFTQR 200
Cdd:COG3850 85 LLAALLSLLLLLLLLLLLLLLLLLLLLAAAINRKLALLRLLLALLLALLLAYLLRRRIVRPLRRLTQAAERIARGDFDAR 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446840827 201 ANISGRNEMAMLGTALNNMSAELAESYAVLEQRVQEKTAGLEHKNQILSFLWQANRRLHSRAPLCERLSPVLNGLQNLTL 280
Cdd:COG3850 165 VPVSGRDELGTLARAFNRMADELQELYAELEEEEELEAELELLALLDELLLLAALLLLLALLLALLLAALLAALLLLLLL 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446840827 281 LRDIELRVYDTDDEENHQEFTCQPDMTCDDKGCQLCPRGVLPVGDRGTTLKWRLADSHTQYGILLATLPQGRHLSHDQQQ 360
Cdd:COG3850 245 QDALAESELLALNILAGLLELLLALLLLLLASALLLLELELLALLLELVELLALAAAEEALLLLVELAALLLLLLLQAIA 324
|
330 340 350 360
....*....|....*....|....*....|....*....|
gi 446840827 361 LVDTLVEQLTATLALDRHQERQQQLIVMEERATIARELHD 400
Cdd:COG3850 325 NASLLLIALASVVAALLELASILALQAALEAAAAGAALAA 364
|
|
| BaeS |
COG0642 |
Signal transduction histidine kinase [Signal transduction mechanisms]; |
329-583 |
2.61e-09 |
|
Signal transduction histidine kinase [Signal transduction mechanisms];
Pssm-ID: 440407 [Multi-domain] Cd Length: 328 Bit Score: 59.15 E-value: 2.61e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446840827 329 TLKWRLADSHTQYGILLATLPQGRHLSHDQQQLVDTLVEQLTATLALDRHQERQQQLIvmeerATIArelHDsIAQSLSC 408
Cdd:COG0642 57 ALLALLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLALLLLLEEANEAKSRFL-----ANVS---HE-LRTPLTA 127
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446840827 409 MKMQvscLQMQGDALPESSRELLSQIRNELNASWAQLRELLTTFRLQLTEPGLRPA-------LEASCEEYSAKFGFP-V 480
Cdd:COG0642 128 IRGY---LELLLEELDEEQREYLETILRSADRLLRLINDLLDLSRLEAGKLELEPEpvdlaelLEEVVELFRPLAEEKgI 204
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446840827 481 KLDYQLPPRLVPSH-QAIHLLQIAREALSNALKHSQA-SEVVVTVAQNDNQVKLTVQDNGCGVPE--------------N 544
Cdd:COG0642 205 ELELDLPDDLPTVRgDPDRLRQVLLNLLSNAIKYTPEgGTVTVSVRREGDRVRISVEDTGPGIPPedlerifepffrtdP 284
|
250 260 270 280
....*....|....*....|....*....|....*....|.
gi 446840827 545 AIRSNHYGM--IIMRDRAQSLRGDCRVRRRESGGTEVVVTF 583
Cdd:COG0642 285 SRRGGGTGLglAIVKRIVELHGGTIEVESEPGKGTTFTVTL 325
|
|
| NarQ_sensor |
cd22899 |
ligand binding sensor domain of NarQ, and related chemoreceptors; The periplasmic ligand ... |
44-138 |
7.40e-09 |
|
ligand binding sensor domain of NarQ, and related chemoreceptors; The periplasmic ligand binding sensor domain of NarQ is a histidine kinase receptor that responds to nitrate and nitrite to effect regulation of anaerobic respiration in various bacteria and similar proteins. It forms a homodimer and binds to ligands such as nitrate via the dimerization interface, a feature that appears to be conserved in this domain superfamily. NarQ-NarP sensor-response regulator pair controls Escherichia coli gene expression in response to nitrate and nitrite. NarQ has been shown to interact equally with NarP and NarL response regulators; NarL is the sensor response partner of NarX.
Pssm-ID: 438631 [Multi-domain] Cd Length: 116 Bit Score: 53.68 E-value: 7.40e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446840827 44 AHAINKAGSLRMQSYRLLAAVplsEKDKPL----IKEMEQTAFSAELTRAaerDGQL------AQLQGLQDYWRnELIPT 113
Cdd:cd22899 7 AEAINVAGSLRMQSYRLAYDL---ESESPLleqhIAQYEQSLHSPALQSL---DRWYvpdevkQRYQQLLARWQ-EMKQY 79
|
90 100
....*....|....*....|....*
gi 446840827 114 LmRAQNRETVSADVSQFVAGLDQLV 138
Cdd:cd22899 80 L-LQGDPASYLQQVASYVDQIDQFV 103
|
|
| WalK |
COG5002 |
Sensor histidine kinase WalK [Signal transduction mechanisms]; |
406-577 |
7.43e-09 |
|
Sensor histidine kinase WalK [Signal transduction mechanisms];
Pssm-ID: 444026 [Multi-domain] Cd Length: 390 Bit Score: 58.03 E-value: 7.43e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446840827 406 LSCMKMQVSCLQMQGDALPESSRELLSQIRNELNASWAQLRELLTTFRLQLTEPGLRPA-------LEASCEEYSAKFG- 477
Cdd:COG5002 180 LTSIRGYLELLLDGAADDPEERREYLEIILEEAERLSRLVNDLLDLSRLESGELKLEKEpvdlaelLEEVVEELRPLAEe 259
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446840827 478 FPVKLDYQLPPRLVPSH-QAIHLLQIAREALSNALKHSQA-SEVVVTVAQNDNQVKLTVQDNGCGVPENAIrsNH----- 550
Cdd:COG5002 260 KGIELELDLPEDPLLVLgDPDRLEQVLTNLLDNAIKYTPEgGTITVSLREEDDQVRISVRDTGIGIPEEDL--PRiferf 337
|
170 180
....*....|....*....|....*..
gi 446840827 551 YgmiimrdraqslRGDcRVRRRESGGT 577
Cdd:COG5002 338 Y------------RVD-KSRSRETGGT 351
|
|
| HAMP |
smart00304 |
HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain; |
177-228 |
3.32e-08 |
|
HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain;
Pssm-ID: 197640 [Multi-domain] Cd Length: 53 Bit Score: 49.94 E-value: 3.32e-08
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 446840827 177 RLLQPWRQLLAMASAVSHRDFTQRANISGRNEMAMLGTALNNMSAELAESYA 228
Cdd:smart00304 2 RLLRPLRRLAEAAQRIADGDLTVRLPVDGRDEIGELARAFNEMADRLEETIA 53
|
|
| HAMP |
pfam00672 |
HAMP domain; |
173-225 |
6.62e-08 |
|
HAMP domain;
Pssm-ID: 459898 [Multi-domain] Cd Length: 53 Bit Score: 49.16 E-value: 6.62e-08
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 446840827 173 WLRARLLQPWRQLLAMASAVSHRDFTQRANISGRNEMAMLGTALNNMSAELAE 225
Cdd:pfam00672 1 LLARRILRPLRRLAEAARRIASGDLDVRLPVSGRDEIGELARAFNQMAERLRE 53
|
|
| HAMP |
cd06225 |
Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain; ... |
179-223 |
1.45e-07 |
|
Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain; HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices connected by an extended linker. The structure of the Af1503 HAMP dimer from Archaeoglobus fulgidus has been solved using nuclear magnetic resonance, revealing a parallel four-helix bundle; this structure has been confirmed by cross-linking analysis of HAMP domains from the Escherichia coli aerotaxis receptor Aer. It has been suggested that the four-helix arrangement can rotate between the unusually packed conformation observed in the NMR structure and a canonical coiled-coil arrangement. Such rotation may coincide with signal transduction, but a common mechanism by which HAMP domains relay a variety of input signals has yet to be established.
Pssm-ID: 381743 [Multi-domain] Cd Length: 45 Bit Score: 47.82 E-value: 1.45e-07
10 20 30 40
....*....|....*....|....*....|....*....|....*
gi 446840827 179 LQPWRQLLAMASAVSHRDFTQRANISGRNEMAMLGTALNNMSAEL 223
Cdd:cd06225 1 TRPLRRLTEAARRIAEGDLDVRVPVRSKDEIGELARAFNQMAERL 45
|
|
| HATPase_EL346-LOV-HK-like |
cd16951 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
491-583 |
2.16e-07 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Erythrobacter litoralis blue light-activated histidine kinase 2; This domain family includes the histidine kinase-like ATPase (HATPase) domain of blue light-activated histidine kinase 2 of Erythrobacter litoralis (EL346). Signaling commonly occurs within HK dimers, however EL346 functions as a monomer. Also included in this family are the HATPase domains of ethanolamine utilization sensory transduction histidine kinase (EutW), whereby regulation of ethanolamine, a carbon and nitrogen source for gut bacteria, results in autophosphorylation and subsequent phosphoryl transfer to a response regulator (EutV) containing an RNA-binding domain. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some have an accessory PAS sensor domain, while some have an N-terminal histidine kinase domain.
Pssm-ID: 340427 [Multi-domain] Cd Length: 131 Bit Score: 50.11 E-value: 2.16e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446840827 491 VPSHQAIHLLQIAREALSNALKH--SQASEVVVTV-AQNDN-QVKLTVQDNGCGVPE--NAIRSNHYGMIIMRDRAQSLR 564
Cdd:cd16951 32 VSSEVATAIGLVVNELLQNALKHafSDREGGTITIrSVVDGdYLRITVIDDGVGLPQdeDWPNKGSLGLQIVRSLVEGEL 111
|
90
....*....|....*....
gi 446840827 565 GDCRVRRRESGGTEVVVTF 583
Cdd:cd16951 112 KAFLEVQSAENGTRVNIDI 130
|
|
| Tar |
COG0840 |
Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms]; |
9-225 |
3.78e-07 |
|
Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms];
Pssm-ID: 440602 [Multi-domain] Cd Length: 533 Bit Score: 53.10 E-value: 3.78e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446840827 9 LTLVNQVALIVLLSTAIGLAGMAVSGWLVQGVQGSAHAINKAGSLRMQSYRLLAAVPLSEKDKPLIKEMEQTAFSAELTR 88
Cdd:COG0840 34 ALLLAALTALALLLLLSLLALLLLLLLLALALLLVLLALLLLLALVVLLALLLALLLLLLALLALALAALALLAALAALL 113
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446840827 89 AAERDGQLAQLQGLQDYWRNELIPTLMRAQNRETVSADVSQFVAGLDQLVSGFDRTTEMRIETVVLVHRVMAVFMALLLV 168
Cdd:COG0840 114 ALLELLLAALLAALAIALLALAALLALAALALALLALALLAAAAAAAAALAALLEAAALALAAAALALALLAAALLALVA 193
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 446840827 169 FTII---WLRARLLQPWRQLLAMASAVSHRDFTQRANISGRNEMAMLGTALNNMSAELAE 225
Cdd:COG0840 194 LAIIlalLLSRSITRPLRELLEVLERIAEGDLTVRIDVDSKDEIGQLADAFNRMIENLRE 253
|
|
| RsbW |
COG2172 |
Anti-sigma regulatory factor (Ser/Thr protein kinase) [Signal transduction mechanisms]; |
491-583 |
1.23e-06 |
|
Anti-sigma regulatory factor (Ser/Thr protein kinase) [Signal transduction mechanisms];
Pssm-ID: 441775 [Multi-domain] Cd Length: 127 Bit Score: 47.99 E-value: 1.23e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446840827 491 VPSHQAIHLLQIAREALSNALKHSQAS----EVVVTVAQNDNQVKLTVQDNGCGVPENAI-------RSNHYGMIIMRdr 559
Cdd:COG2172 27 LDEDDADDLVLAVSEAVTNAVRHAYGGdpdgPVEVELELDPDGLEIEVRDEGPGFDPEDLpdpystlAEGGRGLFLIR-- 104
|
90 100
....*....|....*....|....
gi 446840827 560 aqSLRGDCRVRRREsGGTEVVVTF 583
Cdd:COG2172 105 --RLMDEVEYESDP-GGTTVRLVK 125
|
|
| CitA |
COG3290 |
Sensor histidine kinase DipB regulating citrate/malate metabolism [Signal transduction ... |
480-583 |
6.68e-06 |
|
Sensor histidine kinase DipB regulating citrate/malate metabolism [Signal transduction mechanisms];
Pssm-ID: 442519 [Multi-domain] Cd Length: 389 Bit Score: 48.69 E-value: 6.68e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446840827 480 VKLDYQLPPRLVPSHqaiHLLQIAREALSNALKHSQASE-----VVVTVAQNDNQVKLTVQDNGCGVPENAIRS------ 548
Cdd:COG3290 266 IDIDSDLPDLPLSDT---DLVTILGNLLDNAIEAVEKLPeeerrVELSIRDDGDELVIEVEDSGPGIPEELLEKifergf 342
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 446840827 549 ------NH-YGMIIMRDRAQSLRGDCRVRRRESGGTEVVVTF 583
Cdd:COG3290 343 stklgeGRgLGLALVKQIVEKYGGTIEVESEEGEGTVFTVRL 384
|
|
| COG4191 |
COG4191 |
Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal ... |
374-547 |
7.03e-06 |
|
Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal transduction mechanisms];
Pssm-ID: 443345 [Multi-domain] Cd Length: 361 Bit Score: 48.64 E-value: 7.03e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446840827 374 ALDRHQERQQQLIVMEERATIArEL-----HDsIAQSLSCMKMQVSCLQ--MQGDALPESSRELLSQIRNELNASWAQLR 446
Cdd:COG4191 122 AEEELRELQEQLVQSEKLAALG-ELaagiaHE-INNPLAAILGNAELLRrrLEDEPDPEELREALERILEGAERAAEIVR 199
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446840827 447 ELLTTFRLQLTEPG---LRPALEASCEEYSAKFG-FPVKLDYQLPPRLVPSH-------QAI-HLLQIAREALsnalKHS 514
Cdd:COG4191 200 SLRAFSRRDEEEREpvdLNELIDEALELLRPRLKaRGIEVELDLPPDLPPVLgdpgqleQVLlNLLINAIDAM----EEG 275
|
170 180 190
....*....|....*....|....*....|...
gi 446840827 515 QASEVVVTVAQNDNQVKLTVQDNGCGVPENAIR 547
Cdd:COG4191 276 EGGRITISTRREGDYVVISVRDNGPGIPPEVLE 308
|
|
| HATPase_RsbW-like |
cd16936 |
Histidine kinase-like ATPase domain of RsbW, an anti sigma-B factor and serine-protein kinase ... |
505-583 |
1.44e-05 |
|
Histidine kinase-like ATPase domain of RsbW, an anti sigma-B factor and serine-protein kinase involved in regulating sigma-B during stress in Bacilli, and related domains; This family includes histidine kinase-like ATPase (HATPase) domain of RsbW, an anti sigma-B factor as well as a serine-protein kinase involved in regulating sigma-B during stress in Bacilli. The alternative sigma factor sigma-B is an important regulator of the general stress response of Bacillus cereus and B. subtilis. RsbW is an anti-sigma factor while RsbV is an anti-sigma factor antagonist (anti-anti-sigma factor). RsbW can also act as a kinase on RsbV. In a partner-switching mechanism, RsbW, RsbV, and sigma-B participate as follows: in non-stressed cells, sigma-B is present in an inactive form complexed with RsbW; in this form, sigma-B is unable to bind to RNA polymerase. Under stress, RsbV binds to RsbW, forming an RsbV-RsbW complex, and sigma-B is released to bind to RNA polymerase. RsbW may then act as a kinase on RsbV, phosphorylating a serine residue; RsbW is then released to bind to sigma-B, hence blocking its ability to bind RNA polymerase. A phosphatase then dephosphorylates RsbV so that it can again form a complex with RsbW, leading to the release of sigma-B.
Pssm-ID: 340413 [Multi-domain] Cd Length: 91 Bit Score: 43.80 E-value: 1.44e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446840827 505 EALSNALKHSQAS----EVVVTVAQNDNQVKLTVQDNGCGV-------PENAIRSNHYGMIIMRdraqSLRGDCRVRRRE 573
Cdd:cd16936 7 EAVTNAVRHAYRHdgpgPVRLELDLDPDRLRVEVTDSGPGFdplrpadPDAGLREGGRGLALIR----ALMDEVGYRRTP 82
|
90
....*....|
gi 446840827 574 sGGTEVVVTF 583
Cdd:cd16936 83 -GGKTVWLEL 91
|
|
| PilJ |
pfam13675 |
Type IV pili methyl-accepting chemotaxis transducer N-term; This domain is found on many type ... |
35-110 |
2.10e-05 |
|
Type IV pili methyl-accepting chemotaxis transducer N-term; This domain is found on many type IV pili methyl-accepting chemotaxis transducer proteins where there is also a HAMP signature towards the C-terminus. It is a monomodular four-helix bundle and recognizes nitrate and nitrite (Matilla et al. FEMS Microbiology Reviews, fuab043, 45, 2021, 1. https://doi.org/10.1093/femsre/fuab043).
Pssm-ID: 433397 [Multi-domain] Cd Length: 112 Bit Score: 44.00 E-value: 2.10e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446840827 35 WLVQGVQGSAHAINKAGSLRMQSYRL----LAAVPLSEKDKPLIKEMEQTAFSAELTRAAERDGQL------------AQ 98
Cdd:pfam13675 1 WTLWQSEGDAAAINAAGSLRMQSQRLaksvLLALAGNYDLAEAFADLEESIDQFDRTLAALALGDLarglfvpagairAQ 80
|
90
....*....|..
gi 446840827 99 LQGLQDYWRNEL 110
Cdd:pfam13675 81 LEAVQPLWERLR 92
|
|
| HATPase_PhoQ-like |
cd16954 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
507-583 |
2.54e-05 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli PhoQ and Providencia stuartii AarG; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Escherichia coli PhoQ and Providencia stuartii AarG. PhoQ is the histidine kinase (HK) of the PhoP-PhoQ two-component regulatory system (TCS), which responds to the levels of Mg2+ and Ca2+, controls virulence, mediates the adaptation to Mg2+-limiting environments, and regulates numerous cellular activities. Providencia stuartii AarG is a putative sensor kinase which controls the expression of the 2'-N-acetyltransferase and an intrinsic multiple antibiotic resistance (Mar) response in Providencia stuartii. The AarG product is similar to PhoQ in that it is able to restore wild-type levels of resistance to a Salmonella typhimurium phoQ mutant. However, the expression of the 2'-N-acetyltransferase gene and of aarP (a gene encoding a transcriptional activator of 2'-N-acetyltransferase) are not significantly affected by the levels of Mg2+ or Ca2+. Most proteins in this group contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some have an accessory HAMP sensor domain, and some have an intracellular membrane -interaction PhoQ sensor domain.
Pssm-ID: 340430 [Multi-domain] Cd Length: 135 Bit Score: 44.16 E-value: 2.54e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446840827 507 LSNALKHSQaSEVVVTVAQNDNQVKLTVQDNGCGVPENAI-------------RSNH-YGMIIMRDRAQSLRGDCRVRRR 572
Cdd:cd16954 46 LDNACKWCL-EFVEVTARQTDGGLHLIVDDDGPGVPESQRskifqrgqrldeqRPGQgLGLAIAKEIVEQYGGELSLSDS 124
|
90
....*....|.
gi 446840827 573 ESGGTEVVVTF 583
Cdd:cd16954 125 PLGGARFEVVF 135
|
|
| YesM |
COG2972 |
Sensor histidine kinase YesM [Signal transduction mechanisms]; |
482-583 |
3.93e-05 |
|
Sensor histidine kinase YesM [Signal transduction mechanisms];
Pssm-ID: 442211 [Multi-domain] Cd Length: 445 Bit Score: 46.55 E-value: 3.93e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446840827 482 LDYQLPPRLvpshqaihlLQIAREalsNALKHS-----QASEVVVTVAQNDNQVKLTVQDNGCGVPENAI---------- 546
Cdd:COG2972 332 LDLLIPKLI---------LQPLVE---NAIEHGiepkeGGGTIRISIRKEGDRLVITVEDNGVGMPEEKLeklleelssk 399
|
90 100 110 120
....*....|....*....|....*....|....*....|.
gi 446840827 547 -RSNHYGMIIMRDRAQSLRGD---CRVRRRESGGTEVVVTF 583
Cdd:COG2972 400 gEGRGIGLRNVRERLKLYYGEeygLEIESEPGEGTTVTIRI 440
|
|
| PRK11100 |
PRK11100 |
sensory histidine kinase CreC; Provisional |
418-583 |
4.00e-05 |
|
sensory histidine kinase CreC; Provisional
Pssm-ID: 236846 [Multi-domain] Cd Length: 475 Bit Score: 46.38 E-value: 4.00e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446840827 418 MQGDALPESSRELLSQIRNE-----------LN-ASWAQLRELLTTFRLQLtEPGLRPALEASCEEYSAKfgfPVKLDYQ 485
Cdd:PRK11100 281 LQEDPPPEDRARFTGNILTQsarlqqlidrlLElARLEQRQELEVLEPVAL-AALLEELVEAREAQAAAK---GITLRLR 356
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446840827 486 LPPRLVPS-----HQAIHLLqiareaLSNALKHS-QASEVVVTVAQNDNQVKLTVQDNGCGVPENAI------------- 546
Cdd:PRK11100 357 PDDARVLGdpfllRQALGNL------LDNAIDFSpEGGTITLSAEVDGEQVALSVEDQGPGIPDYALpriferfyslprp 430
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 446840827 547 ----RSNHYGMIIMRDRAQSLRGDCRVRRRESGGTEVVVTF 583
Cdd:PRK11100 431 angrKSTGLGLAFVREVARLHGGEVTLRNRPEGGVLATLTL 471
|
|
| HAMP |
COG2770 |
HAMP domain [Signal transduction mechanisms]; |
9-467 |
5.59e-05 |
|
HAMP domain [Signal transduction mechanisms];
Pssm-ID: 442051 [Multi-domain] Cd Length: 631 Bit Score: 46.26 E-value: 5.59e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446840827 9 LTLVNQVALIVLLSTAIGLAGMAVSGWLVQGVQGSAHAINKAGSLRMQSYRLLAAVPLSEKDKPLIKEMEQTAFSAELTR 88
Cdd:COG2770 72 AAALLLLLLLLSLVALAALLLALLLLLLLALLLLLAALLLLLLLAALALLLLLLLLLAALLALLLALALLALLLGLAAAR 151
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446840827 89 AAERDGQLAQLQGLQDYWRNELIPTLMRAQNRETVSADVSQFVAGLdQLVSGFDRTTEMRIETVVLVhrvmAVFMALLLV 168
Cdd:COG2770 152 LLLAALLALAAALALALGAGELLLLADLAAAIAALLAALLLLLLGG-LLLVVLLEAALAALLLLLLL----ALLALLLAL 226
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446840827 169 FTIIWLRARLLQPWRQLLAMASAVSHRDFTQRANISGRNEMAMLGTALNNMSAELAESYAVLEQRVQEKTAGLEHKNQIL 248
Cdd:COG2770 227 LLALLLARRITRPLRRLAEAARRIAAGDLDVRIPVSRKDEIGELARAFNRMADSLRESIEEAEEEEELAEAELARLLEAL 306
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446840827 249 SFLWQANRRLHSRAPLCERLSPVLNGLQNLTLLRDIELRVYDTDDEENHQEFTCQPDMTCDDKGCQLCPRGVLPVGDRGT 328
Cdd:COG2770 307 LELLLALLLLLLALLLLAAAALLLELLLLLLLALLLLLLLAADLLLALALAALLLLLALELLLEAELLVLLALEALALEA 386
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446840827 329 TLKWRLADSHTQYGILLATLPQGRHLSHDQQQLVDTLVEQLTATLALDRHQERQQQLIVMEERATIARELHDSIAQSLSC 408
Cdd:COG2770 387 ELAAVLALLAALAAALLLLELALEELVLALLALALLALAAAAAAAEAAAAALELAAAAIAAAAAAEAEGGLAELEAEELV 466
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*....
gi 446840827 409 MKMQVSCLQMQGDALPESSRELLSQIRNELNASWAQLRELLTTFRLQLTEPGLRPALEA 467
Cdd:COG2770 467 AAAEALLLLAALLLLAALGALELLLLEEEEEAGAAAEELAEELLLLEGLLLLLLLEAEA 525
|
|
| HATPase_BceS-YxdK-YvcQ-like |
cd16948 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
499-543 |
5.86e-05 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis BceS, YxdK, and Bacillus thuringiensis YvcQ; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Bacillus subtilis BceS and Bacillus thuringiensis YvcQ, the HKs of the two-component regulatory system (TCSs) BceS-BceR and YvcQ-YvcP, repsectively, which are both involved in regulating bacitracin resistance. It also includes the HATPase domain of YxdK, the HK of YxdK-YxdJ TCS involved in sensing antimicrobial compounds.
Pssm-ID: 340424 [Multi-domain] Cd Length: 109 Bit Score: 42.66 E-value: 5.86e-05
10 20 30 40
....*....|....*....|....*....|....*....|....*.
gi 446840827 499 LLQIAREALSNALKHS-QASEVVVTVAQNDNQVKLTVQDNGCGVPE 543
Cdd:cd16948 6 LSFIIGQIVSNALKYSkQGGKIEIYSETNEQGVVLSIKDFGIGIPE 51
|
|
| HATPase_EvgS-ArcB-TorS-like |
cd16922 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases, many are hybrid ... |
499-546 |
4.90e-04 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases, many are hybrid sensor histidine kinases, similar to Escherichia coli EvgS, ArcB, TorS, BarA, RcsC; This family contains the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinases (HKs), including the following Escherichia coli HKs: EvgS, a HK of the EvgS-EvgA two-component system (TCS) that confers acid resistance; ArcB, a HK of the ArcB-ArcA TCS that modulates the expression of numerous genes in response to respiratory growth conditions; TorS, a HK of the TorS-TorR TCS which is involved in the anaerobic utilization of trimethylamine-N-oxide; BarA, a HK of the BarA-UvrY TCS involved in the regulation of carbon metabolism; and RcsC, a HK of the RcsB-RcsC TCS which regulates the expression of the capsule operon and of the cell division gene ftsZ. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), with most having accessory sensor domain(s) such as GAF, PAS and CHASE; many are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340399 [Multi-domain] Cd Length: 110 Bit Score: 39.78 E-value: 4.90e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 446840827 499 LLQIAREALSNALKHSQASEVVVTVA-----QNDNQVKLTVQDNGCGVPENAI 546
Cdd:cd16922 1 LRQILLNLLGNAIKFTEEGEVTLRVSleeeeEDGVQLRFSVEDTGIGIPEEQQ 53
|
|
| KinA |
COG5805 |
Sporulation sensor histidine kinase A (Stage II sporulation protein SpoIIF/SpoIIJ) [Cell cycle ... |
497-546 |
5.75e-04 |
|
Sporulation sensor histidine kinase A (Stage II sporulation protein SpoIIF/SpoIIJ) [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444507 [Multi-domain] Cd Length: 496 Bit Score: 42.80 E-value: 5.75e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 446840827 497 IHLLQIAREALSNAlkhsqaSEVVVTVAQNDNQVKLTVQDNGCGVPENAI 546
Cdd:COG5805 401 INLIKNAIEAMPNG------GTITIHTEEEDNSVIIRVIDEGIGIPEERL 444
|
|
| HATPase_CpxA-like |
cd16949 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
507-577 |
6.40e-04 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli CpxA; This family includes the histidine kinase-like ATPase (HATPase) domains of two-component sensor histidine kinase (HKs) similar to Escherichia coli CpxA, HK of the CpxA-CpxR two-component regulatory system (TCS) which may function in acid stress and in cell wall stability. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also contain a CpxA family periplasmic domain.
Pssm-ID: 340425 [Multi-domain] Cd Length: 104 Bit Score: 39.62 E-value: 6.40e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446840827 507 LSNALKHSQaSEVVVTVAQNDNQVKLTVQDNGCGVPENAIRSnhygmiIMRD--RAQSlrgdcrVRRRESGGT 577
Cdd:cd16949 9 LRNALRYSP-SKILLDISQDGDQWTITITDDGPGVPEDQLEQ------IFLPfyRVDS------ARDRESGGT 68
|
|
| PRK15048 |
PRK15048 |
methyl-accepting chemotaxis protein II; Provisional |
158-228 |
6.84e-04 |
|
methyl-accepting chemotaxis protein II; Provisional
Pssm-ID: 185008 [Multi-domain] Cd Length: 553 Bit Score: 42.69 E-value: 6.84e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446840827 158 VMAVFMALLLVFTIIWLRARLLQPWRQLLAMASAVSHRDFTQRANISGRNEMAMLGTALNNMSAELAESYA 228
Cdd:PRK15048 196 VIALVVVLILLVAWYGIRRMLLTPLAKIIAHIREIAGGNLANTLTIDGRSEMGDLAQSVSHMQRSLTDTVT 266
|
|
| cpxA |
PRK09470 |
envelope stress sensor histidine kinase CpxA; |
509-577 |
1.26e-03 |
|
envelope stress sensor histidine kinase CpxA;
Pssm-ID: 236532 [Multi-domain] Cd Length: 461 Bit Score: 41.46 E-value: 1.26e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446840827 509 NALKHSQaSEVVVTVAQNDNQVKLTVQDNGCGVPEnairsnhygmiimRDRAQSLRGDCRV---RRRESGGT 577
Cdd:PRK09470 364 NALRYSH-TKIEVAFSVDKDGLTITVDDDGPGVPE-------------EEREQIFRPFYRVdeaRDRESGGT 421
|
|
| PRK13560 |
PRK13560 |
hypothetical protein; Provisional |
495-583 |
1.29e-03 |
|
hypothetical protein; Provisional
Pssm-ID: 106506 [Multi-domain] Cd Length: 807 Bit Score: 41.97 E-value: 1.29e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446840827 495 QAIHLLQIAREALSNALKH----SQASEVVVTVA-QNDNQVKLTVQDNGCGVPENA--IRSNHYGMIIMRDRAQSLRGDC 567
Cdd:PRK13560 708 KAIPCGLIISELLSNALKHafpdGAAGNIKVEIReQGDGMVNLCVADDGIGLPAGFdfRAAETLGLQLVCALVKQLDGEI 787
|
90
....*....|....*.
gi 446840827 568 RVRRResGGTEVVVTF 583
Cdd:PRK13560 788 ALDSR--GGARFNIRF 801
|
|
| PRK15347 |
PRK15347 |
two component system sensor kinase; |
160-286 |
1.46e-03 |
|
two component system sensor kinase;
Pssm-ID: 237951 [Multi-domain] Cd Length: 921 Bit Score: 41.55 E-value: 1.46e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446840827 160 AVFMALLLVFTIIW-LRARLLQPWRQLLAMASAVSHRDFTQRANISGRNEMAMLGTALNNMSAELAESYAVLEQRVQEKT 238
Cdd:PRK15347 302 ALLILVLLTSVLFLlLRRYLAKPLWRFVDIINKTGPAALEPRLPENRLDELGSIAKAYNQLLDTLNEQYDTLENKVAERT 381
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 446840827 239 AGLEHKNQILSflwQANRR--LHSRAPLCERLSPvLNG-LQNLTLLRDIEL 286
Cdd:PRK15347 382 QALAEAKQRAE---QANKRksEHLTTISHEIRTP-LNGvLGALELLQNTPL 428
|
|
| NtrB |
COG3852 |
Signal transduction histidine kinase NtrB, nitrogen specific [Signal transduction mechanisms]; |
365-543 |
3.10e-03 |
|
Signal transduction histidine kinase NtrB, nitrogen specific [Signal transduction mechanisms];
Pssm-ID: 443061 [Multi-domain] Cd Length: 361 Bit Score: 40.21 E-value: 3.10e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446840827 365 LVEQLTATLALDRHQERQQQLIVMEEratIAREL-HD------SIAQSLSCMKMQVSclqmqgdalPESSRELLSQIRNE 437
Cdd:COG3852 112 VLRDITERKRLERELRRAEKLAAVGE---LAAGLaHEirnpltGIRGAAQLLERELP---------DDELREYTQLIIEE 179
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446840827 438 LNaswaQLRELLTTFrLQLTEPG--------LRPALEASCEEYSAKFGFPVKLDYQLPPRLVPS-------HQAI-HLLQ 501
Cdd:COG3852 180 AD----RLNNLVDRL-LSFSRPRpperepvnLHEVLERVLELLRAEAPKNIRIVRDYDPSLPEVlgdpdqlIQVLlNLVR 254
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 446840827 502 IAREALSNA----LKHSQASEVVVTVAQNDNQVKLTVQDNGCGVPE 543
Cdd:COG3852 255 NAAEAMPEGgtitIRTRVERQVTLGGLRPRLYVRIEVIDNGPGIPE 300
|
|
| HATPase_TopVIB-like |
cd16933 |
Histidine kinase-like ATPase domain of type IIB topoisomerase, Topo VI, subunit B; This family ... |
499-546 |
6.59e-03 |
|
Histidine kinase-like ATPase domain of type IIB topoisomerase, Topo VI, subunit B; This family includes the histidine kinase-like ATPase (HATPase) domain of the B subunit of topoisomerase VI (Topo VIB). Topo VI is a heterotetrameric complex composed of two TopVIA and two TopVIB subunits and is categorized as a type II B DNA topoisomerase. It is found in archaea and also in plants. Type II enzymes cleave both strands of a DNA duplex and pass a second duplex through the resulting break in an ATP-dependent mechanism. DNA cleavage by Topo VI generates two-nucleotide 5'-protruding ends.
Pssm-ID: 340410 [Multi-domain] Cd Length: 203 Bit Score: 38.10 E-value: 6.59e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 446840827 499 LLQIAREALSNAL----KHSQASEVVVTVAQNDNQ-VKLTVQDNGCGVPENAI 546
Cdd:cd16933 20 LYTTVRELVENSLdateEAGILPDIKVEIEEIGKDhYKVIVEDNGPGIPEEQI 72
|
|
| HATPase_CreC-like |
cd16945 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
504-576 |
7.67e-03 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli CreC; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Escherichia coli CreC of the CreC-CreB two-component regulatory system (TCS) involved in catabolic regulation. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and accessory sensory domain(s) such as HAMP, CACHE or PAS.
Pssm-ID: 340421 [Multi-domain] Cd Length: 106 Bit Score: 36.28 E-value: 7.67e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446840827 504 REALSNALKH-----SQASEVVVTVAQNDNQVKLTVQDNGCGVPENAI-----------------RSNHYGMIIMRDRAQ 561
Cdd:cd16945 6 RQAINNLLDNaidfsPEGGLIALQLEADTEGIELLVFDEGSGIPDYALnrvferfyslprphsgqKSTGLGLAFVQEVAQ 85
|
90
....*....|....*
gi 446840827 562 SLRGDCRVRRRESGG 576
Cdd:cd16945 86 LHGGRITLRNRPDGV 100
|
|
| PRK15347 |
PRK15347 |
two component system sensor kinase; |
496-541 |
7.86e-03 |
|
two component system sensor kinase;
Pssm-ID: 237951 [Multi-domain] Cd Length: 921 Bit Score: 39.24 E-value: 7.86e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*.
gi 446840827 496 AIHLLQIAREALSNALKHSQASEVVVTVAQNDNQVKLTVQDNGCGV 541
Cdd:PRK15347 511 SLRLRQILVNLLGNAVKFTETGGIRLRVKRHEQQLCFTVEDTGCGI 556
|
|
| COG4251 |
COG4251 |
Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal ... |
507-543 |
9.22e-03 |
|
Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal transduction mechanisms];
Pssm-ID: 443393 [Multi-domain] Cd Length: 503 Bit Score: 39.00 E-value: 9.22e-03
10 20 30 40
....*....|....*....|....*....|....*....|
gi 446840827 507 LSNALKHSQASE---VVVTVAQNDNQVKLTVQDNGCGVPE 543
Cdd:COG4251 403 ISNAIKYSRPGEpprIEIGAEREGGEWVFSVRDNGIGIDP 442
|
|
| |
