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Conserved domains on  [gi|446797934|ref|WP_000875190|]
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MULTISPECIES: MotA/TolQ/ExbB proton channel family protein [Salmonella]

Protein Classification

MotA/TolQ/ExbB proton channel family protein( domain architecture ID 669)

MotA/TolQ/ExbB proton channel family protein similar to flagellar motor protein MotA and biopolymer transporter ExbB/TolQ

Gene Ontology:  GO:0016020|GO:0015252
TCDB:  1.A.30

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
MotA_ExbB super family cl46600
MotA/TolQ/ExbB proton channel family; This family groups together integral membrane proteins ...
 117-202 1.76e-04

MotA/TolQ/ExbB proton channel family; This family groups together integral membrane proteins that appear to be involved translocation of proteins across a membrane. These proteins are probably proton channels. MotA is an essential component of the flageller motor that uses a proton gradient to generate rotational motion in the flageller. ExbB is part of the TonB-dependent transduction complex. The TonB complex uses the proton gradient across the inner bacterial membrane to transport large molecules across the outer bacterial membrane.


The actual alignment was detected with superfamily member pfam01618:

Pssm-ID: 460268  Cd Length: 120  Bit Score: 40.92  E-value: 1.76e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446797934  117 QRLSFIMSCSNVSTLVGLLGTFAGLSITIGSIGNLLSSPSDVGGdnasntlnmivtmvaslseplkGMNTAFVSSIYGVV 196
Cdd:pfam01618  43 RGLSILATIGSLAPLLGLLGTVLGLIHAFQNLGDAGPGLSALAP----------------------GIAEALIATAYGLF 100


                  ....*.
gi 446797934  197 CAILLT 202
Cdd:pfam01618 101 VAIPAL 106
 
Name Accession Description Interval E-value
MotA_ExbB pfam01618
MotA/TolQ/ExbB proton channel family; This family groups together integral membrane proteins ...
 117-202 1.76e-04

MotA/TolQ/ExbB proton channel family; This family groups together integral membrane proteins that appear to be involved translocation of proteins across a membrane. These proteins are probably proton channels. MotA is an essential component of the flageller motor that uses a proton gradient to generate rotational motion in the flageller. ExbB is part of the TonB-dependent transduction complex. The TonB complex uses the proton gradient across the inner bacterial membrane to transport large molecules across the outer bacterial membrane.


Pssm-ID: 460268  Cd Length: 120  Bit Score: 40.92  E-value: 1.76e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446797934  117 QRLSFIMSCSNVSTLVGLLGTFAGLSITIGSIGNLLSSPSDVGGdnasntlnmivtmvaslseplkGMNTAFVSSIYGVV 196
Cdd:pfam01618  43 RGLSILATIGSLAPLLGLLGTVLGLIHAFQNLGDAGPGLSALAP----------------------GIAEALIATAYGLF 100


                  ....*.
gi 446797934  197 CAILLT 202
Cdd:pfam01618 101 VAIPAL 106
 
Name Accession Description Interval E-value
MotA_ExbB pfam01618
MotA/TolQ/ExbB proton channel family; This family groups together integral membrane proteins ...
 117-202 1.76e-04

MotA/TolQ/ExbB proton channel family; This family groups together integral membrane proteins that appear to be involved translocation of proteins across a membrane. These proteins are probably proton channels. MotA is an essential component of the flageller motor that uses a proton gradient to generate rotational motion in the flageller. ExbB is part of the TonB-dependent transduction complex. The TonB complex uses the proton gradient across the inner bacterial membrane to transport large molecules across the outer bacterial membrane.


Pssm-ID: 460268  Cd Length: 120  Bit Score: 40.92  E-value: 1.76e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446797934  117 QRLSFIMSCSNVSTLVGLLGTFAGLSITIGSIGNLLSSPSDVGGdnasntlnmivtmvaslseplkGMNTAFVSSIYGVV 196
Cdd:pfam01618  43 RGLSILATIGSLAPLLGLLGTVLGLIHAFQNLGDAGPGLSALAP----------------------GIAEALIATAYGLF 100


                  ....*.
gi 446797934  197 CAILLT 202
Cdd:pfam01618 101 VAIPAL 106
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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