|
Name |
Accession |
Description |
Interval |
E-value |
| T4SS-DNA_transf |
pfam02534 |
Type IV secretory system Conjugative DNA transfer; These proteins contain a P-loop and ... |
120-568 |
2.89e-93 |
|
Type IV secretory system Conjugative DNA transfer; These proteins contain a P-loop and walker-B site for nucleotide binding. TraG is essential for DNA transfer in bacterial conjugation. These proteins are thought to mediate interactions between the DNA-processing (Dtr) and the mating pair formation (Mpf) systems. The C-terminus of this domain interacts with the relaxosome component TraM via the latter's tetramerization domain. TraD is a hexameric ring ATPase that forms the cytoplasmic face of the conjugative pore. The family contains a number of different DNA transfer proteins.
Pssm-ID: 367119 [Multi-domain] Cd Length: 468 Bit Score: 295.08 E-value: 2.89e-93
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446769846 120 SFTLDGD-------EKDGIIVGIKDKKIIRYVGA----------AFSAMGAGTRAGKGAGIVITNLMKYWWSVIILDPKR 182
Cdd:pfam02534 1 RWANDGDlesagllTRENTIIGDVYTKDPDAWYAggllntdgdfSHVLVFAGTGSGKGVGVVIPNLLVWKGSIVVLDPKG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446769846 183 ECFNITSLIRKVIlGHEVYKFDPFSPVTH-RFNPLYYVSMGTSEGFNQLENLSLIIYPYKTDGADAGsyLNKTAGGVFks 261
Cdd:pfam02534 81 ELWELTSGIREKQ-GRKVFVLEPFNPKTSdRYNPLDYIDRGSEQETEDILKVASLIMPGKGGGRDDF--FNNTARQLL-- 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446769846 262 yaVALWFMIKNdKAGLKTLD--IEPVFSMskinqlfeRAEPEHLLSFMNDIR-SELRGKDktLADIGVAgLKAFIEMEDK 338
Cdd:pfam02534 156 --VALIALVLR-SKPTRTIGqtLRFVRNM--------LSEPNLIENKELAVLlNELDGSH--HDRVGDN-LRFYVNKTDE 221
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446769846 339 TKAQLKSNFLNGLSPFANPNVANATDGNDFDLRQVRKKRMTIYFCISGDNARLAEKITNIFFQLAIQVNLEKMPTDDPEI 418
Cdd:pfam02534 222 TRSSVIGTAVSELALYADPEVRNATSGSDFDLRDLRRDKTSVYVILNPKDLTVVSPLLRVFFQMVVELLYLKLPNGDGRP 301
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446769846 419 KHdCLFLLDEFPSIGAVDYIKSKSGLIAGYKLKLLIVYQVGSQLEEIYSYAGSKTLLASAPCKIVYSAS-DVKDARELSE 497
Cdd:pfam02534 302 KE-VLFLLDEFPSLGKLEILEEALATIRGYGIRLTTICQSISQLKETYGGEGAKSILSNHAVVICFAASnDEETAKYISK 380
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446769846 498 AMGTRTVTIGSKSKSRSRGGTSRSESESLIERPLVTTNELLTLKFSEEILAMKGENPIRCEKAFYYLNEYF 568
Cdd:pfam02534 381 LLGKTTVEVESSSKSTDAKGSSRSRSISEVQRPLLTPDEVLRMPDDEQIVITKGQPPIKCKKALYFKDEDF 451
|
|
| VirD4 |
COG3505 |
Type IV secretory pathway, VirD4 component, TraG/TraD family ATPase [Intracellular trafficking, ... |
153-563 |
4.05e-81 |
|
Type IV secretory pathway, VirD4 component, TraG/TraD family ATPase [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 442728 [Multi-domain] Cd Length: 402 Bit Score: 261.46 E-value: 4.05e-81
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446769846 153 AGTRAGKGAGIVITNLMKYW--WSVIILDPKRECFNITSLIRKvILGHEVYKFDPFSPV-THRFNPLYYVsmgtsEGFNQ 229
Cdd:COG3505 6 GPTGSGKTVGLVIPNLTQLArgESVVVTDPKGDLAELTAGFRR-RAGYDVYVFDPFDPErSHRWNPLDEI-----RDPAD 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446769846 230 LENLSLIIYPYKTDGADAGSYLNKTAGGVFksyAVALWFMIKNDKAGLKTLdiepvfsmskinqlferaePEHLLSFMND 309
Cdd:COG3505 80 AQELAEALIPALGGGGGGDPFWREAARALL---AALILALAEEGRRTLADV-------------------YRLLSEPEEE 137
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446769846 310 IRSELRGKDKTLADIGVAGLKAFIEMEDKTKAQLKSNFLNGLSPFANPNVANATDGNDFDLRQVRKKRMTIYFCISGDNA 389
Cdd:COG3505 138 LRELLEALPESPHPPVADTLAAFLNAAEKTRSSVLSTLASALELLSDPEVAALTSGSDFDLRDLIREKGTLYLVLPPDDL 217
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446769846 390 RLAEKITNIFFQLAIQVNLEKMPTDDpEIKHDCLFLLDEFPSIGAVDYIKSKSGLIAGYKLKLLIVYQVGSQLEEIYSYA 469
Cdd:COG3505 218 STLAPLLRLLLSQLIRALLRRAERSG-RLPRPVLLLLDEFANLGRLPSLETLLATGRGYGIRLVLILQSLAQLEAIYGEE 296
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446769846 470 GSKTLLASAPCKIVYSASDVKDARELSEAMGTRTVTigSKSKSRSRGGTSRSESEslIERPLVTTNELLTLKFSEEILAM 549
Cdd:COG3505 297 GAETILGNCGTKIFLGVNDPETAEYLSELLGKRTVE--RRSESRSRGSRSRSRSE--QERPLLTPDELRRLPDGEAIVLV 372
|
410
....*....|....
gi 446769846 550 KGENPIRCEKAFYY 563
Cdd:COG3505 373 RGGPPIRAKKIRYY 386
|
|
| PRK13897 |
PRK13897 |
type IV secretion system component VirD4; Provisional |
1-568 |
7.31e-48 |
|
type IV secretion system component VirD4; Provisional
Pssm-ID: 237549 [Multi-domain] Cd Length: 606 Bit Score: 177.30 E-value: 7.31e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446769846 1 MKTFNKSQSVFIFAVM---LVAAWFAGSFIFFVLYFSQIKNLKpLKAVFRSIDAYRMDIF-TDSLTLSVVTTDIRILAF- 75
Cdd:PRK13897 3 HKILNHIRNILGHAIIhfvVLEFCFYISGAFFALFTWGPGALD-FNAINPSIADFPWAYWpTIFNYIINVWGQPKIYDYn 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446769846 76 --VALGAGFVVSLIIPVAALIKLNE---------KKENIFGDARFATINDIRESNSFTldgdeKDGIIVGiKDKKIIrYV 144
Cdd:PRK13897 82 lkLKLLASLLGPAIIVIIFYIKLRErikswrpfkKKEKVHGDARWASESDIRKAGLRS-----KKGMLLG-KDKGGY-FV 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446769846 145 GAAF--SAMGAGTRAGKGAGIVITNLMKYWWSVIILDPKRECFNITSLIRKVIlGHEVYKFDPFSP--VTHRFNPLYYVS 220
Cdd:PRK13897 155 ADGFqhALLFAPTGSGKGVGFVIPNLLFWEDSVVVHDIKLENYELTSGWREKQ-GQKVFVWEPANPdgISHCYNPLDWVS 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446769846 221 MGTSEGFNQLENLSLIIYPYKtdgadagSYLNKTAGGVFksYAVALWFMIKNDKAglKTLDiEPVFSMSKINQLFERA-- 298
Cdd:PRK13897 234 TKPGQMVDDVQKIANLIMPEQ-------DFWNNEARSLF--LGVVLYLLADPEKV--KSFG-EVVRTMRSDDVVYNLAvv 301
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446769846 299 -----EPEHLLSFMNdirselrgkdktladigvagLKAFIEMEDKTKAQLKSNFLNGLSPFANPNVANATDGNDFDLRQV 373
Cdd:PRK13897 302 ldtlgKVIHPVAYMN--------------------IAAFLQKADKERSGVISTMNSSLELWANPLIDTATASSDFNIQEF 361
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446769846 374 RKKRMTIYFCISGDNARLAEKITNIFFQLAIQVNLEKMPTDDPeiKHDCLFLLDEFPSIGAVDYIKSKSGLIAGYKLKLL 453
Cdd:PRK13897 362 KKKKTTVYVGLTPDNLTRLQPLMQVFYQQATEFLCRKLPDKDE--PYGVLFLMDEFPTLGKMEQFKTGIAYFRGYRVRLF 439
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446769846 454 IVYQVGSQLEEIYSYAGSKTLLASAPCKIVYSASDVKDARELSEAMGTRTVTIGSKSKSR--SRGGTSRSESESLIERPL 531
Cdd:PRK13897 440 LIIQDTEQLKGIYEEAGMNSFLSNSTYRITFAANNIETANLISQLVGNKTVEQESLNKPKflDLNPASRSLHISEVQRAL 519
|
570 580 590
....*....|....*....|....*....|....*..
gi 446769846 532 VTTNELLTLKFSEEILAMKGENPIRCEKAFYYLNEYF 568
Cdd:PRK13897 520 LLPQEVIMLPRDEQILLIESTYPIKSKKIKYYEDKFF 556
|
|
| TrwB_TraG_TraD_VirD4 |
cd01127 |
TrwB/TraG/TraD/VirD4 family of bacterial conjugation proteins; The TraG/TraD/VirD4 family are ... |
374-483 |
1.17e-10 |
|
TrwB/TraG/TraD/VirD4 family of bacterial conjugation proteins; The TraG/TraD/VirD4 family are bacterial conjugation proteins involved in type IV secretion (T4S) systems, versatile bacterial secretion systems mediating transport of protein and/or DNA. They are present in gram-negative and gram-positive bacteria, as well as archaea. They form hexameric rings and belong to the RecA-like NTPases superfamily, which also includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases.
Pssm-ID: 410871 [Multi-domain] Cd Length: 144 Bit Score: 59.93 E-value: 1.17e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446769846 374 RKKRMTIY------FCISGDNARLAEKITNIFFQLAIQVNLEKMPTDDPEIKHDCLFLLDEFPSIGAVDYIKSKSGLIAG 447
Cdd:cd01127 26 RGGSVIITdpkgelFLVIPDRDDSFAALRALFFNQLFRALTELASLSPGRLPRRVWFILDEFANLGRIPNLPNLLATGRK 105
|
90 100 110
....*....|....*....|....*....|....*.
gi 446769846 448 YKLKLLIVYQVGSQLEEIYSYAGSKTLLASAPCKIV 483
Cdd:cd01127 106 RGISVVLILQSLAQLEAVYGKDGAQTILGNCNTKLY 141
|
|
|
|
Name |
Accession |
Description |
Interval |
E-value |
| T4SS-DNA_transf |
pfam02534 |
Type IV secretory system Conjugative DNA transfer; These proteins contain a P-loop and ... |
120-568 |
2.89e-93 |
|
Type IV secretory system Conjugative DNA transfer; These proteins contain a P-loop and walker-B site for nucleotide binding. TraG is essential for DNA transfer in bacterial conjugation. These proteins are thought to mediate interactions between the DNA-processing (Dtr) and the mating pair formation (Mpf) systems. The C-terminus of this domain interacts with the relaxosome component TraM via the latter's tetramerization domain. TraD is a hexameric ring ATPase that forms the cytoplasmic face of the conjugative pore. The family contains a number of different DNA transfer proteins.
Pssm-ID: 367119 [Multi-domain] Cd Length: 468 Bit Score: 295.08 E-value: 2.89e-93
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446769846 120 SFTLDGD-------EKDGIIVGIKDKKIIRYVGA----------AFSAMGAGTRAGKGAGIVITNLMKYWWSVIILDPKR 182
Cdd:pfam02534 1 RWANDGDlesagllTRENTIIGDVYTKDPDAWYAggllntdgdfSHVLVFAGTGSGKGVGVVIPNLLVWKGSIVVLDPKG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446769846 183 ECFNITSLIRKVIlGHEVYKFDPFSPVTH-RFNPLYYVSMGTSEGFNQLENLSLIIYPYKTDGADAGsyLNKTAGGVFks 261
Cdd:pfam02534 81 ELWELTSGIREKQ-GRKVFVLEPFNPKTSdRYNPLDYIDRGSEQETEDILKVASLIMPGKGGGRDDF--FNNTARQLL-- 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446769846 262 yaVALWFMIKNdKAGLKTLD--IEPVFSMskinqlfeRAEPEHLLSFMNDIR-SELRGKDktLADIGVAgLKAFIEMEDK 338
Cdd:pfam02534 156 --VALIALVLR-SKPTRTIGqtLRFVRNM--------LSEPNLIENKELAVLlNELDGSH--HDRVGDN-LRFYVNKTDE 221
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446769846 339 TKAQLKSNFLNGLSPFANPNVANATDGNDFDLRQVRKKRMTIYFCISGDNARLAEKITNIFFQLAIQVNLEKMPTDDPEI 418
Cdd:pfam02534 222 TRSSVIGTAVSELALYADPEVRNATSGSDFDLRDLRRDKTSVYVILNPKDLTVVSPLLRVFFQMVVELLYLKLPNGDGRP 301
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446769846 419 KHdCLFLLDEFPSIGAVDYIKSKSGLIAGYKLKLLIVYQVGSQLEEIYSYAGSKTLLASAPCKIVYSAS-DVKDARELSE 497
Cdd:pfam02534 302 KE-VLFLLDEFPSLGKLEILEEALATIRGYGIRLTTICQSISQLKETYGGEGAKSILSNHAVVICFAASnDEETAKYISK 380
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446769846 498 AMGTRTVTIGSKSKSRSRGGTSRSESESLIERPLVTTNELLTLKFSEEILAMKGENPIRCEKAFYYLNEYF 568
Cdd:pfam02534 381 LLGKTTVEVESSSKSTDAKGSSRSRSISEVQRPLLTPDEVLRMPDDEQIVITKGQPPIKCKKALYFKDEDF 451
|
|
| VirD4 |
COG3505 |
Type IV secretory pathway, VirD4 component, TraG/TraD family ATPase [Intracellular trafficking, ... |
153-563 |
4.05e-81 |
|
Type IV secretory pathway, VirD4 component, TraG/TraD family ATPase [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 442728 [Multi-domain] Cd Length: 402 Bit Score: 261.46 E-value: 4.05e-81
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446769846 153 AGTRAGKGAGIVITNLMKYW--WSVIILDPKRECFNITSLIRKvILGHEVYKFDPFSPV-THRFNPLYYVsmgtsEGFNQ 229
Cdd:COG3505 6 GPTGSGKTVGLVIPNLTQLArgESVVVTDPKGDLAELTAGFRR-RAGYDVYVFDPFDPErSHRWNPLDEI-----RDPAD 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446769846 230 LENLSLIIYPYKTDGADAGSYLNKTAGGVFksyAVALWFMIKNDKAGLKTLdiepvfsmskinqlferaePEHLLSFMND 309
Cdd:COG3505 80 AQELAEALIPALGGGGGGDPFWREAARALL---AALILALAEEGRRTLADV-------------------YRLLSEPEEE 137
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446769846 310 IRSELRGKDKTLADIGVAGLKAFIEMEDKTKAQLKSNFLNGLSPFANPNVANATDGNDFDLRQVRKKRMTIYFCISGDNA 389
Cdd:COG3505 138 LRELLEALPESPHPPVADTLAAFLNAAEKTRSSVLSTLASALELLSDPEVAALTSGSDFDLRDLIREKGTLYLVLPPDDL 217
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446769846 390 RLAEKITNIFFQLAIQVNLEKMPTDDpEIKHDCLFLLDEFPSIGAVDYIKSKSGLIAGYKLKLLIVYQVGSQLEEIYSYA 469
Cdd:COG3505 218 STLAPLLRLLLSQLIRALLRRAERSG-RLPRPVLLLLDEFANLGRLPSLETLLATGRGYGIRLVLILQSLAQLEAIYGEE 296
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446769846 470 GSKTLLASAPCKIVYSASDVKDARELSEAMGTRTVTigSKSKSRSRGGTSRSESEslIERPLVTTNELLTLKFSEEILAM 549
Cdd:COG3505 297 GAETILGNCGTKIFLGVNDPETAEYLSELLGKRTVE--RRSESRSRGSRSRSRSE--QERPLLTPDELRRLPDGEAIVLV 372
|
410
....*....|....
gi 446769846 550 KGENPIRCEKAFYY 563
Cdd:COG3505 373 RGGPPIRAKKIRYY 386
|
|
| PRK13897 |
PRK13897 |
type IV secretion system component VirD4; Provisional |
1-568 |
7.31e-48 |
|
type IV secretion system component VirD4; Provisional
Pssm-ID: 237549 [Multi-domain] Cd Length: 606 Bit Score: 177.30 E-value: 7.31e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446769846 1 MKTFNKSQSVFIFAVM---LVAAWFAGSFIFFVLYFSQIKNLKpLKAVFRSIDAYRMDIF-TDSLTLSVVTTDIRILAF- 75
Cdd:PRK13897 3 HKILNHIRNILGHAIIhfvVLEFCFYISGAFFALFTWGPGALD-FNAINPSIADFPWAYWpTIFNYIINVWGQPKIYDYn 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446769846 76 --VALGAGFVVSLIIPVAALIKLNE---------KKENIFGDARFATINDIRESNSFTldgdeKDGIIVGiKDKKIIrYV 144
Cdd:PRK13897 82 lkLKLLASLLGPAIIVIIFYIKLRErikswrpfkKKEKVHGDARWASESDIRKAGLRS-----KKGMLLG-KDKGGY-FV 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446769846 145 GAAF--SAMGAGTRAGKGAGIVITNLMKYWWSVIILDPKRECFNITSLIRKVIlGHEVYKFDPFSP--VTHRFNPLYYVS 220
Cdd:PRK13897 155 ADGFqhALLFAPTGSGKGVGFVIPNLLFWEDSVVVHDIKLENYELTSGWREKQ-GQKVFVWEPANPdgISHCYNPLDWVS 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446769846 221 MGTSEGFNQLENLSLIIYPYKtdgadagSYLNKTAGGVFksYAVALWFMIKNDKAglKTLDiEPVFSMSKINQLFERA-- 298
Cdd:PRK13897 234 TKPGQMVDDVQKIANLIMPEQ-------DFWNNEARSLF--LGVVLYLLADPEKV--KSFG-EVVRTMRSDDVVYNLAvv 301
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446769846 299 -----EPEHLLSFMNdirselrgkdktladigvagLKAFIEMEDKTKAQLKSNFLNGLSPFANPNVANATDGNDFDLRQV 373
Cdd:PRK13897 302 ldtlgKVIHPVAYMN--------------------IAAFLQKADKERSGVISTMNSSLELWANPLIDTATASSDFNIQEF 361
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446769846 374 RKKRMTIYFCISGDNARLAEKITNIFFQLAIQVNLEKMPTDDPeiKHDCLFLLDEFPSIGAVDYIKSKSGLIAGYKLKLL 453
Cdd:PRK13897 362 KKKKTTVYVGLTPDNLTRLQPLMQVFYQQATEFLCRKLPDKDE--PYGVLFLMDEFPTLGKMEQFKTGIAYFRGYRVRLF 439
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446769846 454 IVYQVGSQLEEIYSYAGSKTLLASAPCKIVYSASDVKDARELSEAMGTRTVTIGSKSKSR--SRGGTSRSESESLIERPL 531
Cdd:PRK13897 440 LIIQDTEQLKGIYEEAGMNSFLSNSTYRITFAANNIETANLISQLVGNKTVEQESLNKPKflDLNPASRSLHISEVQRAL 519
|
570 580 590
....*....|....*....|....*....|....*..
gi 446769846 532 VTTNELLTLKFSEEILAMKGENPIRCEKAFYYLNEYF 568
Cdd:PRK13897 520 LLPQEVIMLPRDEQILLIESTYPIKSKKIKYYEDKFF 556
|
|
| PRK13850 |
PRK13850 |
type IV secretion system protein VirD4; Provisional |
80-619 |
6.25e-39 |
|
type IV secretion system protein VirD4; Provisional
Pssm-ID: 237531 [Multi-domain] Cd Length: 670 Bit Score: 152.33 E-value: 6.25e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446769846 80 AGFVVSLIIPVAALIKLNEKKENIFGDARFATINDIRESnSFTLDGDEKDGIIVG--IKDKKIIRYVGAA---FSAMGAG 154
Cdd:PRK13850 69 AIVVSTSVVVLLSQLIVSLRNREHHGTARWAEEGEMRHA-GYLQRYSRITGPIFGktCGPRWFGSYLTNGeqpHSLVVAP 147
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446769846 155 TRAGKGAGIVITNLMKYWWSVIILDPKRECFNITSLIRKViLGHEVYKFDPFSPV--THRFNP-LYYVSMGTSEGFNQLE 231
Cdd:PRK13850 148 TRAGKGVGVVIPTLLTFKGSVIALDVKGELFELTSRARKA-SGDAVFKFAPLDPErrTHCYNPvLDIAALPPERRFTETR 226
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446769846 232 NL--SLIIypykTDGADAGSYLNktagGVFKSYAVALWFMIKNDkaglkTLDIEPVFSmskinqLFerAEPEHLLSFMND 309
Cdd:PRK13850 227 RLaaNLIT----AKGKGAEGFID----GARDLFVAGILACIERG-----TPTIGAVYD------LF--AQPGEKYKLFAQ 285
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446769846 310 IRSELRGKDktladigvaGLKAFIEMEDkTKAQLKSNFLN-----GLSPFANPNVANATDGNDFDLRQVRKKRMTIYFCI 384
Cdd:PRK13850 286 LAEETQNKE---------AQRIFDNMAG-NDTKILTSYTSvlgdgGLNLWADPLVKAATSRSDFSVYDLRRKRTCIYLCV 355
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446769846 385 SGDNARLAEKITNIFFQLAIQVNLEKMPTDDPeiKHDCLFLLDEFPSIGAVDYIKSKSGLIAGYKLKLLIVYQVGSQLEE 464
Cdd:PRK13850 356 SPNDLEVVAPLMRLLFQQVVSILQRSLPGKDE--RHEVLFLLDEFKHLGKLEAIETAITTIAGYKGRFMFIIQSLSALTG 433
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446769846 465 IYSYAGSKTLLASAPCKIVYSASDVKDARELSEAMGTRTVTIGSKSKSRSRGGTSRSEsESLIERPLVTTNELLTLKFSE 544
Cdd:PRK13850 434 TYDEAGKQNFLSNTGVQVFMATADDETPTYISKAIGDYTFKARSTSYSQARMFDHNIQ-ISDQGAPLLRPEQVRLLDDDT 512
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446769846 545 EILAMKGENPIRCEKAFYYLNEyffgdfvkvapELANIFPRKKGKLVMPPQKVF-ENEIVAKGYLAVKDVPDLDKA 619
Cdd:PRK13850 513 EIVLIKGQPPLKLRKVRYYSDR-----------ELKRIFEAQTGSLPEPASLMLpDDTNARRKHLPQPAASSTDQA 577
|
|
| TraG-D_C |
pfam12696 |
TraM recognition site of TraD and TraG; This family includes both TraG and TraD as well as ... |
422-542 |
9.46e-27 |
|
TraM recognition site of TraD and TraG; This family includes both TraG and TraD as well as VirD4 proteins. TraG is essential for DNA transfer in bacterial conjugation. These proteins are thought to mediate interactions between the DNA-processing (Dtr) and the mating pair formation (Mpf) systems. This domain interacts with the relaxosome component TraM via the latter's tetramerization domain. TraD is a hexameric ring ATPase that forms the cytoplasmic face of the conjugative pore.
Pssm-ID: 432726 [Multi-domain] Cd Length: 125 Bit Score: 105.42 E-value: 9.46e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446769846 422 CLFLLDEFPSIGAVDYIKSKSGLIAGYKLKLLIVYQVGSQLEEIYSYAGSKTLLASAPCKIVYSASDVKDARELSEAMGT 501
Cdd:pfam12696 2 VLFVLDEFANLGKIPDLEKLISTGRSRGISLMLILQSIAQLEELYGKDGAETILGNCNTKVFLGGGDEETAKYLSKLLGK 81
|
90 100 110 120
....*....|....*....|....*....|....*....|....
gi 446769846 502 RTVTIGSKSKSRSRGGT---SRSESESLIERPLVTTNELLTLKF 542
Cdd:pfam12696 82 YTVVSTTTSSSSSGSGGsgsSSSSSSQLVGRPLLTPDELRRLPR 125
|
|
| PRK13822 |
PRK13822 |
conjugal transfer coupling protein TraG; Provisional |
72-563 |
9.07e-24 |
|
conjugal transfer coupling protein TraG; Provisional
Pssm-ID: 237522 [Multi-domain] Cd Length: 641 Bit Score: 105.82 E-value: 9.07e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446769846 72 ILAFVALGAGFVVSLIIPVA---ALIKLNEKKENIFGDARFATINDIRESnsFTLDGdekdGIIVGIK---DKKIIRYVg 145
Cdd:PRK13822 125 VVGFFAGAFALRVSLVGNAAfarAEPRRIRGKRAIHGDADWMKMKEAAKL--FPPDG----GIVIGERyrvDKDSVAAL- 197
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446769846 146 aAFSAM-----GAGTR------------------AGKGA----GIVITNLMKYWWSVIILDPKRECFNITSLIRKViLGH 198
Cdd:PRK13822 198 -PFRPDdrttwGKGGKaplltfdgdfgsthglvfAGSGGfkttSVVVPTALKWGGPLVVLDPSTEVAPMVSEHRRD-AGR 275
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446769846 199 EVYKFDPFSPVThrfnplyyvsmgtseGFNQLenlsliiypyktDGADAGSYLnKTAGGVfksyAVALWFMIKNDKAGLK 278
Cdd:PRK13822 276 EVIVLDPTNPGT---------------GFNVL------------DWIGRSGGT-KEEDIV----AVASWILSDSKRTESS 323
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446769846 279 TLDiepvfsmskinqlFERAEPEHLLS-FMNDI--RSELRGKDKTLADigvagLKAFI-EMEDKTKAQLKSNFLNGLSPF 354
Cdd:PRK13822 324 RDD-------------FFRNSAHQLLTaLLAHVclSGEYEGKERTLRT-----LRAILsEPEPSLRARLRDIYENSESDF 385
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446769846 355 ANPNV---------------ANATD---------------GNDFDLRQVRKKRMTIYFCISG----DNARLAEKITNIFf 400
Cdd:PRK13822 386 IRENVgvfvnmteqtfsgvyATASKdtqwlsypnyaalvsGNSFSTSDLAAGNTDVFINIPLkileSYPGLARVIIGSL- 464
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446769846 401 qlaiqvnLEKMPTDDPEIKHDCLFLLDEFPSIG-------AVDyiksksgliAG--YKLKLLIVYQVGSQLEEIYSYAGS 471
Cdd:PRK13822 465 -------LNAMYNADGNVKGRALFLLDEVARLGymriletARD---------AGrkYGITLMLIYQSIGQLREHFGGRGA 528
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446769846 472 KTLLASAPCkIVYSA-SDVKDARELSEAMGTRTVTIGSKSKSRSRGGTSRSESESLIERPLVTTNELL-TLKFSEEILAM 549
Cdd:PRK13822 529 TSWFESASW-ISFAAiKDLDTADYISERCGEMTVEVDQTSRSSGWSGSSRSRSKQLQRRPLIMPHEILqSMRADEQIIFV 607
|
570
....*....|....
gi 446769846 550 KGENPIRCEKAFYY 563
Cdd:PRK13822 608 QGNPPLRCGRAIYF 621
|
|
| PRK13880 |
PRK13880 |
conjugal transfer coupling protein TraG; Provisional |
76-540 |
3.45e-23 |
|
conjugal transfer coupling protein TraG; Provisional
Pssm-ID: 237540 Cd Length: 636 Bit Score: 104.05 E-value: 3.45e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446769846 76 VALGAGFVvSLIIPVAALIKLNEKKENIFGDARFATINDIRES-----------NSFTLDGDEKDGIIVG-IKDKK---- 139
Cdd:PRK13880 90 VVSTVGLL-GVAVAKVVTSNSSKANEYLHGSARWAEKKDIQAAgllprernvleIVTGKAAPTATGVYVGgWQDKDgnfh 168
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446769846 140 IIRYVGAAFSAMGAGTRAGKGAGIVITNLMKYWWSVIILDPKRECFNITSLIRKVILGHEVYKFDPFSPV-THRFNPLYY 218
Cdd:PRK13880 169 YLRHNGPEHVLTYAPTRSGKGVGLVVPTLLSWGHSSVITDLKGELWALTAGWRQKHAKNKVLRFEPASLSgSVCWNPLDE 248
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446769846 219 VSMGTSEGFNQLENLS-LIIYPyktDGADAGSYLNKTAggvfksYAVALWFMIkndKAGLKTLDIEPVFSMSKINQLFer 297
Cdd:PRK13880 249 IRLGTEYEVGDVQNLAtLIVDP---DGKGLESHWQKTA------FALLVGVIL---HALYKAKNEGGTATLPSVDAML-- 314
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446769846 298 AEPEHLLsfmNDIRSELRGKD----KTLADIGVAGlKAFIEMEDKTKAQLKSNFLNGLSPFANPNVANATDGNDFDLRQV 373
Cdd:PRK13880 315 ADPNRDI---GELWMEMTTYGhvdgQNHPAIGSAA-RDMMDRPEEEAGSVLSTAKSYLALYRDPVVARNVSRSDFRIKDL 390
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446769846 374 --RKKRMTIYFCIS-GDNARLaEKITNIFFQLAIQVNLEKMPTDD----PEIKHDCLFLLDEFPSIGAVDYIKSKSGLIA 446
Cdd:PRK13880 391 mhHDDPVSLYIVTQpNDKARL-RPLVRVMVNMIVRLLADKMDFENgrpvAHYKHRLLMMLDEFPSLGKLEILQESLAFVA 469
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446769846 447 GYKLKLLIVYQVGSQLEEIYS-YAGSKTLLASAPCKIVYSASDVKDARELSEAMGTRTV-----TIGSKSKSRSRGGTSR 520
Cdd:PRK13880 470 GYGIKCYLICQDINQLKSRETgYGHDESITSNCHVQNAYPPNRVETAEHLSKLTGQTTVvkeqiTTSGRRTSAMLGQVSR 549
|
490 500
....*....|....*....|
gi 446769846 521 SESEslIERPLVTTNELLTL 540
Cdd:PRK13880 550 TYQE--VQRPLLTPDECLRM 567
|
|
| PRK13876 |
PRK13876 |
conjugal transfer coupling protein TraG; Provisional |
50-563 |
1.06e-15 |
|
conjugal transfer coupling protein TraG; Provisional
Pssm-ID: 237538 Cd Length: 663 Bit Score: 80.74 E-value: 1.06e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446769846 50 DAYRMDIFTDSltlsvvttdirilAFVAlGAGFVVSLIIPVA-ALIKLNE-KKENIFGDARFATINDIRESNsftLDGDe 127
Cdd:PRK13876 65 DAYAPHVFDEG-------------GAIA-ASGGFVAIAVAIAmSVWRAREaKRVTTYGSARWAERREIRAAG---LLGP- 126
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446769846 128 kDGIIVGIKDKKIIRYVGA----AFsamgAGTRAGKGAGIVITNLMKYWWSVIILDPKRECFNITSLIRKViLGHeVYKF 203
Cdd:PRK13876 127 -DGVVLGRHDRDYLRHDGPehvlCF----APTRSGKGVGLVVPTLLTWPGSAIVHDIKGENWQLTAGFRAR-FGR-VLLF 199
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446769846 204 DPFSPVTHRFNPLYYVSMGTSEgFNQLENLSLIIY-PyktDGA-DAGSYLNKTaggvfkSYAVALwfmikndKAGLKTLd 281
Cdd:PRK13876 200 DPTNAKSAAYNPLLEVRRGEWE-VRDVQNIADILVdP---EGSlERRNHWEKT------SHALLV-------GAILHVL- 261
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446769846 282 iepvfsmskinqlfeRAEPEHLLS----FMND----IRSELRGKDKTlADIGVAGLKAFI-----EMEDKTKAQLKS--- 345
Cdd:PRK13876 262 ---------------YAEEDKTLAgvanFLSDpkrpIEATLRAMMTT-PHLGEAGPHPVVasaarELLNKSDNERSGvls 325
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446769846 346 ---NFLnGLspFANPNVANATDGNDF---DLrqVRKKR-MTIYFCIS-GDNARLAEKITNIFFQLAIQVNlEKMPTDDPe 417
Cdd:PRK13876 326 tamSFL-GL--YRDPVVAEVTSRCDWriaDL--VAGERpVSLYLVVPpSDISRTKPLIRLILNQIGRRLT-EDLDGKAR- 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446769846 418 iKHDCLFLLDEFPSIGAVDYIKSKSGLIAGYKLKLLIVYQVGSQLEEIYSYAGSktLLASAPCKIVYSASDVKDARELSE 497
Cdd:PRK13876 399 -RHRLLLMLDEFPALGRLDFFESALAFMAGYGIKSFLIAQSLNQIEKAYGQNNS--ILDNCHVRVSFATNDERTAKRVSD 475
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446769846 498 AMGTRTVTIGSKSKSRSRGG-------TSRSESesliERPLVTTNELLTLKFSEEILAMKGENPIRCEKAFYY 563
Cdd:PRK13876 476 ALGTATELRAMKNYAGHRLSpwlghlmVSRQET----ARPLLTPGEVMQLPPDDEIVMVSGVPPIRAKKARYY 544
|
|
| TrwB_AAD_bind |
pfam10412 |
Type IV secretion-system coupling protein DNA-binding domain; The plasmid conjugative coupling ... |
362-540 |
6.64e-13 |
|
Type IV secretion-system coupling protein DNA-binding domain; The plasmid conjugative coupling protein TrwB forms hexamers from six structurally very similar protomers. This hexamer contains a central channel running from the cytosolic pole (made up by the AADs) to the membrane pole ending at the transmembrane pore shaped by 12 transmembrane helices, rendering an overall mushroom-like structure. The TrwB_AAD (all-alpha domain) domain appears to be the DNA-binding domain of the structure. TrwB, a basic integral inner-membrane nucleoside-triphosphate-binding protein, is the structural prototype for the type IV secretion system coupling proteins, a family of proteins essential for macromolecular transport between cells and export.
Pssm-ID: 431268 [Multi-domain] Cd Length: 386 Bit Score: 70.79 E-value: 6.64e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446769846 362 ATDGNDFDLRQ-VRKKRMTIYFCISGDNARLAekITNIFFQ----LAIQVNLEKMPTDDPEIkhdcLFLLDEFPSIGAVD 436
Cdd:pfam10412 186 APDGERFSIREwITEEDPGGWLFITYRADQRA--ALRPLLScwldLAIRALLSLPPSRDRRL----WFFLDELPALGRLP 259
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446769846 437 YIKSKSGLIAGYKLKLLIVYQVGSQLEEIYSYAGSKTLLASAPCKIVYSASDVKDARELSEAMGTR-----TVTIgSKSK 511
Cdd:pfam10412 260 SLKDLLAEGRKFGGAVVLGLQSIAQLREIYGEDGAQTILSNCGTKLILRVSDGETAELCSDLLGDRevermDESL-SYGA 338
|
170 180
....*....|....*....|....*....
gi 446769846 512 SRSRGGTSRSESESliERPLVTTNELLTL 540
Cdd:pfam10412 339 NNSRDGVTLGRQRR--VRPLVLPSEIMNL 365
|
|
| TrwB_TraG_TraD_VirD4 |
cd01127 |
TrwB/TraG/TraD/VirD4 family of bacterial conjugation proteins; The TraG/TraD/VirD4 family are ... |
374-483 |
1.17e-10 |
|
TrwB/TraG/TraD/VirD4 family of bacterial conjugation proteins; The TraG/TraD/VirD4 family are bacterial conjugation proteins involved in type IV secretion (T4S) systems, versatile bacterial secretion systems mediating transport of protein and/or DNA. They are present in gram-negative and gram-positive bacteria, as well as archaea. They form hexameric rings and belong to the RecA-like NTPases superfamily, which also includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases.
Pssm-ID: 410871 [Multi-domain] Cd Length: 144 Bit Score: 59.93 E-value: 1.17e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446769846 374 RKKRMTIY------FCISGDNARLAEKITNIFFQLAIQVNLEKMPTDDPEIKHDCLFLLDEFPSIGAVDYIKSKSGLIAG 447
Cdd:cd01127 26 RGGSVIITdpkgelFLVIPDRDDSFAALRALFFNQLFRALTELASLSPGRLPRRVWFILDEFANLGRIPNLPNLLATGRK 105
|
90 100 110
....*....|....*....|....*....|....*.
gi 446769846 448 YKLKLLIVYQVGSQLEEIYSYAGSKTLLASAPCKIV 483
Cdd:cd01127 106 RGISVVLILQSLAQLEAVYGKDGAQTILGNCNTKLY 141
|
|
| TrwB_TraG_TraD_VirD4 |
cd01127 |
TrwB/TraG/TraD/VirD4 family of bacterial conjugation proteins; The TraG/TraD/VirD4 family are ... |
153-185 |
1.22e-03 |
|
TrwB/TraG/TraD/VirD4 family of bacterial conjugation proteins; The TraG/TraD/VirD4 family are bacterial conjugation proteins involved in type IV secretion (T4S) systems, versatile bacterial secretion systems mediating transport of protein and/or DNA. They are present in gram-negative and gram-positive bacteria, as well as archaea. They form hexameric rings and belong to the RecA-like NTPases superfamily, which also includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases.
Pssm-ID: 410871 [Multi-domain] Cd Length: 144 Bit Score: 39.51 E-value: 1.22e-03
10 20 30
....*....|....*....|....*....|....*
gi 446769846 153 AGTRAGKGAGIVITNLMKYW--WSVIILDPKRECF 185
Cdd:cd01127 6 GTTGSGKTTSIVIPLLDQAArgGSVIITDPKGELF 40
|
|
|