cysteine protease staphopain A [Staphylococcus aureus]
Protein Classification
cysteine protease staphopain( domain architecture ID 10631631)
cysteine protease staphopain is a C47 family peptidase such as staphopain A that plays an important role in the inhibition of host innate immune response, cleaving host elastins found in connective tissues, pulmonary surfactant protein A in the lungs, and the chemokine receptor CXCR2 on leukocytes
List of domain hits
| Name | Accession | Description | Interval | E-value | ||||
| Peptidase_C47 | pfam05543 | Staphopain peptidase C47; Staphopains are one of four major families of proteinases secreted ... |
215-388 | 1.39e-118 | ||||
Staphopain peptidase C47; Staphopains are one of four major families of proteinases secreted by the Gram-positive Staphylococcus aureus. These staphylococcal cysteine proteases are secreted as preproenzymes that are proteolytically cleaved to generate the mature enzyme. : Pssm-ID: 398922 Cd Length: 174 Bit Score: 341.55 E-value: 1.39e-118
|
||||||||
| Staphopain_pro | pfam14731 | Staphopain proregion; This domain is the proregion of the cysteine protease staphopain. Like ... |
37-203 | 1.59e-85 | ||||
Staphopain proregion; This domain is the proregion of the cysteine protease staphopain. Like many papain type peptidases, staphopain is synthesized as an inactive precursor and cleavage of the proregion is required for activation. This proregion has a half-barrel or barrel-sandwich hybrid fold. The proregion blocks the active site cleft of the mature enzyme on one side of the nucleophilic cysteine : Pssm-ID: 291401 Cd Length: 169 Bit Score: 257.21 E-value: 1.59e-85
|
||||||||
| Name | Accession | Description | Interval | E-value | ||||
| Peptidase_C47 | pfam05543 | Staphopain peptidase C47; Staphopains are one of four major families of proteinases secreted ... |
215-388 | 1.39e-118 | ||||
Staphopain peptidase C47; Staphopains are one of four major families of proteinases secreted by the Gram-positive Staphylococcus aureus. These staphylococcal cysteine proteases are secreted as preproenzymes that are proteolytically cleaved to generate the mature enzyme. Pssm-ID: 398922 Cd Length: 174 Bit Score: 341.55 E-value: 1.39e-118
|
||||||||
| Staphopain_pro | pfam14731 | Staphopain proregion; This domain is the proregion of the cysteine protease staphopain. Like ... |
37-203 | 1.59e-85 | ||||
Staphopain proregion; This domain is the proregion of the cysteine protease staphopain. Like many papain type peptidases, staphopain is synthesized as an inactive precursor and cleavage of the proregion is required for activation. This proregion has a half-barrel or barrel-sandwich hybrid fold. The proregion blocks the active site cleft of the mature enzyme on one side of the nucleophilic cysteine Pssm-ID: 291401 Cd Length: 169 Bit Score: 257.21 E-value: 1.59e-85
|
||||||||
| Name | Accession | Description | Interval | E-value | ||||
| Peptidase_C47 | pfam05543 | Staphopain peptidase C47; Staphopains are one of four major families of proteinases secreted ... |
215-388 | 1.39e-118 | ||||
Staphopain peptidase C47; Staphopains are one of four major families of proteinases secreted by the Gram-positive Staphylococcus aureus. These staphylococcal cysteine proteases are secreted as preproenzymes that are proteolytically cleaved to generate the mature enzyme. Pssm-ID: 398922 Cd Length: 174 Bit Score: 341.55 E-value: 1.39e-118
|
||||||||
| Staphopain_pro | pfam14731 | Staphopain proregion; This domain is the proregion of the cysteine protease staphopain. Like ... |
37-203 | 1.59e-85 | ||||
Staphopain proregion; This domain is the proregion of the cysteine protease staphopain. Like many papain type peptidases, staphopain is synthesized as an inactive precursor and cleavage of the proregion is required for activation. This proregion has a half-barrel or barrel-sandwich hybrid fold. The proregion blocks the active site cleft of the mature enzyme on one side of the nucleophilic cysteine Pssm-ID: 291401 Cd Length: 169 Bit Score: 257.21 E-value: 1.59e-85
|
||||||||
| Blast search parameters | ||||
|
