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Conserved domains on  [gi|446735636|ref|WP_000812892|]
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MULTISPECIES: heme lyase NrfEFG subunit NrfG [Enterobacterales]

Protein Classification

PRK10370 family protein( domain architecture ID 11484684)

PRK10370 family protein

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
PRK10370 PRK10370
formate-dependent nitrite reductase complex subunit NrfG; Provisional
 1-198 1.10e-114

formate-dependent nitrite reductase complex subunit NrfG; Provisional


:

Pssm-ID: 182415 [Multi-domain]  Cd Length: 198  Bit Score: 324.55  E-value: 1.10e-114
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446735636   1 MKQPKIPVKMLTTLTILMVFLCVGSYLLSPKWQAVRAEYQRQRDPLHQFASQQTPEAQLQALQDKIRANPQNSEQWALLG 80
Cdd:PRK10370   1 MKLRPIPVKMLTTLTILMVFLCVGSYLLSPKWQAVRAEYQRLADPLHQFASQQTPEAQLQALQDKIRANPQNSEQWALLG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446735636  81 EYYLWQNDYSNSLLAYRQALQLHGENAELYAALATVLYYQASQHMTAQTRAMIDKALALDSNEITALMLLASDAFMQANY 160
Cdd:PRK10370  81 EYYLWRNDYDNALLAYRQALQLRGENAELYAALATVLYYQAGQHMTPQTREMIDKALALDANEVTALMLLASDAFMQADY 160

                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 446735636 161 AQAIELWQKVMDLNSPRINRTQLVESINMAKLLQRRSD 198
Cdd:PRK10370 161 AQAIELWQKVLDLNSPRVNRTQLVESINMAKLLQNRQK 198
 
Name Accession Description Interval E-value
PRK10370 PRK10370
formate-dependent nitrite reductase complex subunit NrfG; Provisional
 1-198 1.10e-114

formate-dependent nitrite reductase complex subunit NrfG; Provisional


Pssm-ID: 182415 [Multi-domain]  Cd Length: 198  Bit Score: 324.55  E-value: 1.10e-114
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446735636   1 MKQPKIPVKMLTTLTILMVFLCVGSYLLSPKWQAVRAEYQRQRDPLHQFASQQTPEAQLQALQDKIRANPQNSEQWALLG 80
Cdd:PRK10370   1 MKLRPIPVKMLTTLTILMVFLCVGSYLLSPKWQAVRAEYQRLADPLHQFASQQTPEAQLQALQDKIRANPQNSEQWALLG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446735636  81 EYYLWQNDYSNSLLAYRQALQLHGENAELYAALATVLYYQASQHMTAQTRAMIDKALALDSNEITALMLLASDAFMQANY 160
Cdd:PRK10370  81 EYYLWRNDYDNALLAYRQALQLRGENAELYAALATVLYYQAGQHMTPQTREMIDKALALDANEVTALMLLASDAFMQADY 160

                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 446735636 161 AQAIELWQKVMDLNSPRINRTQLVESINMAKLLQRRSD 198
Cdd:PRK10370 161 AQAIELWQKVLDLNSPRVNRTQLVESINMAKLLQNRQK 198
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 57-190 6.13e-29

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 104.32  E-value: 6.13e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446735636  57 AQLQALQDKIRANPQNSEQWALLGEYYLWQNDYSNSLLAYRQALQLHGENAELYAALATVLYYQAsqhMTAQTRAMIDKA 136
Cdd:COG4235    1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAG---DTEEAEELLERA 77

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....
gi 446735636 137 LALDSNEITALMLLASDAFMQANYAQAIELWQKVMDLNSPRINRTQLVESINMA 190
Cdd:COG4235   78 LALDPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLALLPADAPARLLEASIAEA 131
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 55-175 3.01e-07

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 49.70  E-value: 3.01e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446735636   55 PEAQLQALQDKIRANPQNSEQWALLGEYYLWQNDYSNSLLAYRQALQLHGENAELYAALATvLYYQASQHmtAQTRAMID 134
Cdd:TIGR02917 549 EEEAVAWLEKAAELNPQEIEPALALAQYYLGKGQLKKALAILNEAADAAPDSPEAWLMLGR-AQLAAGDL--NKAVSSFK 625

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 446735636  135 KALALDSNEITALMLLASDAFMQANYAQAIELWQKVMDLNS 175
Cdd:TIGR02917 626 KLLALQPDSALALLLLADAYAVMKNYAKAITSLKRALELKP 666
 
Name Accession Description Interval E-value
PRK10370 PRK10370
formate-dependent nitrite reductase complex subunit NrfG; Provisional
 1-198 1.10e-114

formate-dependent nitrite reductase complex subunit NrfG; Provisional


Pssm-ID: 182415 [Multi-domain]  Cd Length: 198  Bit Score: 324.55  E-value: 1.10e-114
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446735636   1 MKQPKIPVKMLTTLTILMVFLCVGSYLLSPKWQAVRAEYQRQRDPLHQFASQQTPEAQLQALQDKIRANPQNSEQWALLG 80
Cdd:PRK10370   1 MKLRPIPVKMLTTLTILMVFLCVGSYLLSPKWQAVRAEYQRLADPLHQFASQQTPEAQLQALQDKIRANPQNSEQWALLG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446735636  81 EYYLWQNDYSNSLLAYRQALQLHGENAELYAALATVLYYQASQHMTAQTRAMIDKALALDSNEITALMLLASDAFMQANY 160
Cdd:PRK10370  81 EYYLWRNDYDNALLAYRQALQLRGENAELYAALATVLYYQAGQHMTPQTREMIDKALALDANEVTALMLLASDAFMQADY 160

                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 446735636 161 AQAIELWQKVMDLNSPRINRTQLVESINMAKLLQRRSD 198
Cdd:PRK10370 161 AQAIELWQKVLDLNSPRVNRTQLVESINMAKLLQNRQK 198
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 57-190 6.13e-29

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 104.32  E-value: 6.13e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446735636  57 AQLQALQDKIRANPQNSEQWALLGEYYLWQNDYSNSLLAYRQALQLHGENAELYAALATVLYYQAsqhMTAQTRAMIDKA 136
Cdd:COG4235    1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAG---DTEEAEELLERA 77

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....
gi 446735636 137 LALDSNEITALMLLASDAFMQANYAQAIELWQKVMDLNSPRINRTQLVESINMA 190
Cdd:COG4235   78 LALDPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLALLPADAPARLLEASIAEA 131
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 27-174 1.99e-13

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 67.71  E-value: 1.99e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446735636  27 LLSPKWQAVRAEYQRQRDPLHQFASQQTPEAQLQALQDKIRANPQNSEQWALLGEYYLWQNDYSNSLLAYRQALQLHGEN 106
Cdd:COG3914   66 EAAAAAAALLLLAALLELAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDF 145

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446735636 107 AELYAALATVLYyqaSQHMTAQTRAMIDKALALDSNEITALMLLASDAFMQANYAQAIELWQKVMDLN 174
Cdd:COG3914  146 AEAYLNLGEALR---RLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELD 210
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 32-174 3.83e-10

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 58.47  E-value: 3.83e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446735636  32 WQAVRAEYQRQRDPLHQFASQQtPEAQLQALQDKIRANPQNSEQWALLGEYYLWQNDYSNSLLAYRQALQLHGENAELYA 111
Cdd:COG3914   38 AAALGLALLLLAALAEAAAAAL-LALAAGEAAAAAAALLLLAALLELAALLLQALGRYEEALALYRRALALNPDNAEALF 116

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446735636 112 ALATVLYYQasqHMTAQTRAMIDKALALDSNEITALMLLASDAFMQANYAQAIELWQKVMDLN 174
Cdd:COG3914  117 NLGNLLLAL---GRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELD 176
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 59-174 6.74e-10

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 54.81  E-value: 6.74e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446735636  59 LQALQDKIRANPQNSEQWALLGEYYLWQNDYSNSLLAYRQALQLHGENAELYAALATVLYyqaSQHMTAQTRAMIDKALA 138
Cdd:COG4783   24 EALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALL---KAGDYDEALALLEKALK 100

                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 446735636 139 LDSNEITALMLLASDAFMQANYAQAIELWQKVMDLN 174
Cdd:COG4783  101 LDPEHPEAYLRLARAYRALGRPDEAIAALEKALELD 136
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
66-174 1.48e-08

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 53.09  E-value: 1.48e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446735636  66 IRANPQNSEQWALLGEYYLWQNDYSNSLLAYRQALQLHGENAELYAALATVLYyqaSQHMTAQTRAMIDKALALDSNEIT 145
Cdd:COG0457    1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYL---RLGRYEEALADYEQALELDPDDAE 77

                         90       100
                 ....*....|....*....|....*....
gi 446735636 146 ALMLLASDAFMQANYAQAIELWQKVMDLN 174
Cdd:COG0457   78 ALNNLGLALQALGRYEEALEDYDKALELD 106
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
59-174 1.95e-07

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 49.62  E-value: 1.95e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446735636  59 LQALQDKIRANPQNSEQWALLGEYYLWQNDYSNSLLAYRQALQLHGENAELYAALATVLYyqaSQHMTAQTRAMIDKALA 138
Cdd:COG0457   28 IEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQ---ALGRYEEALEDYDKALE 104

                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 446735636 139 LDSNEITALMLLASDAFMQANYAQAIELWQKVMDLN 174
Cdd:COG0457  105 LDPDDAEALYNLGLALLELGRYDEAIEAYERALELD 140
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
59-169 2.30e-07

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 49.62  E-value: 2.30e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446735636  59 LQALQDKIRANPQNSEQWALLGEYYLWQNDYSNSLLAYRQALQLHGENAELYAALATVLYyqaSQHMTAQTRAMIDKALA 138
Cdd:COG0457   62 LADYEQALELDPDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALL---ELGRYDEAIEAYERALE 138

                         90       100       110
                 ....*....|....*....|....*....|.
gi 446735636 139 LDSNEITALMLLASDAFMQANYAQAIELWQK 169
Cdd:COG0457  139 LDPDDADALYNLGIALEKLGRYEEALELLEK 169
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 55-175 3.01e-07

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 49.70  E-value: 3.01e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446735636   55 PEAQLQALQDKIRANPQNSEQWALLGEYYLWQNDYSNSLLAYRQALQLHGENAELYAALATvLYYQASQHmtAQTRAMID 134
Cdd:TIGR02917 549 EEEAVAWLEKAAELNPQEIEPALALAQYYLGKGQLKKALAILNEAADAAPDSPEAWLMLGR-AQLAAGDL--NKAVSSFK 625

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 446735636  135 KALALDSNEITALMLLASDAFMQANYAQAIELWQKVMDLNS 175
Cdd:TIGR02917 626 KLLALQPDSALALLLLADAYAVMKNYAKAITSLKRALELKP 666
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 59-174 4.09e-07

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 48.96  E-value: 4.09e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446735636  59 LQALQDKIRANPQNSEQWALLGEYYLWQNDYSNSLLAYRQALQLHGENAELYAALATVLyyqASQHMTAQTRAMIDKALA 138
Cdd:COG2956   62 IRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIY---EQEGDWEKAIEVLERLLK 138

                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 446735636 139 LDSNEITALMLLASDAFMQANYAQAIELWQKVMDLN 174
Cdd:COG2956  139 LGPENAHAYCELAELYLEQGDYDEAIEALEKALKLD 174
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 76-174 4.21e-07

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 48.96  E-value: 4.21e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446735636  76 WALLGEYYLWQNDYSNSLLAYRQALQLHGENAELYAALATvLYYQASQHMTAqtRAMIDKALALDSNEITALMLLASDAF 155
Cdd:COG2956   11 WYFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGN-LYRRRGEYDRA--IRIHQKLLERDPDRAEALLELAQDYL 87

                         90
                 ....*....|....*....
gi 446735636 156 MQANYAQAIELWQKVMDLN 174
Cdd:COG2956   88 KAGLLDRAEELLEKLLELD 106
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 56-198 1.50e-06

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 47.42  E-value: 1.50e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446735636  56 EAQLQALQDKIRANPQNSEQWALLGEYYLWQNDYSNSLLAYRQALQLHGENAELYAALATVLyyqASQHMTAQTRAMIDK 135
Cdd:COG2956  127 EKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELY---LEQGDYEEAIAALER 203

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446735636 136 ALALDSNEITALMLLASDAFMQANYAQAIELWQKVMDLNSprinrtQLVESINMAKLLQRRSD 198
Cdd:COG2956  204 ALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDP------SDDLLLALADLLERKEG 260
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 46-174 3.93e-06

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 45.88  E-value: 3.93e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446735636  46 LHQFASQQTPEAqLQALQDKIRANPQNSEQWALLGEYYLWQNDYSNSLLAYRQALQLHGENAELYAALAtVLYYQASQHm 125
Cdd:COG2956   16 LNYLLNGQPDKA-IDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELA-QDYLKAGLL- 92

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*....
gi 446735636 126 tAQTRAMIDKALALDSNEITALMLLASDAFMQANYAQAIELWQKVMDLN 174
Cdd:COG2956   93 -DRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLG 140
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 46-183 4.60e-06

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 46.23  E-value: 4.60e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446735636   46 LHQFASQQTPEAQLQALQDKI-RANPQNSEQWALLGEYYLWQNDYSNSLLAYRQALQLHGENAELYAALATVLYYQasQH 124
Cdd:TIGR02917 165 LAQLALAENRFDEARALIDEVlTADPGNVDALLLKGDLLLSLGNIELALAAYRKAIALRPNNIAVLLALATILIEA--GE 242

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 446735636  125 MtAQTRAMIDKALALDSNEITALMLLASDAFMQANYAQAIELWQKVMDLNSPRINRTQL 183
Cdd:TIGR02917 243 F-EEAEKHADALLKKAPNSPLAHYLKALVDFQKKNYEDARETLQDALKSAPEYLPALLL 300
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 48-171 9.43e-06

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 44.72  E-value: 9.43e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446735636  48 QFASQQTPEAQLQALQDKIRANPQNSEQWALLGEYYLWQNDYSNSLLAYRQALQLHGENAELYAALATvLYYQASQhmTA 127
Cdd:COG2956  153 LYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAE-LYEKLGD--PE 229

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....
gi 446735636 128 QTRAMIDKALALDSNeITALMLLASDAFMQANYAQAIELWQKVM 171
Cdd:COG2956  230 EALELLRKALELDPS-DDLLLALADLLERKEGLEAALALLERQL 272
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 68-174 9.59e-06

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 45.46  E-value: 9.59e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446735636   68 ANPQNSEQWALLGEYYLWQNDYSNSLLAYRQALQLHGENAELYAALAtvlYYQASQHMTAQTRAMIDKALALDSNEITAL 147
Cdd:TIGR02917 120 DDEGAAELLALRGLAYLGLGQLELAQKSYEQALAIDPRSLYAKLGLA---QLALAENRFDEARALIDEVLTADPGNVDAL 196

                          90       100
                  ....*....|....*....|....*..
gi 446735636  148 MLLASDAFMQANYAQAIELWQKVMDLN 174
Cdd:TIGR02917 197 LLKGDLLLSLGNIELALAAYRKAIALR 223
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
82-174 1.35e-05

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 42.08  E-value: 1.35e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446735636  82 YYLWQNDYSNSLLAYRQALQLHGENAELYAALAtVLYYQASQHMTAQTramIDKALALDSNEITALMLLASDAFMQANYA 161
Cdd:COG3063    1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLG-LLLLEQGRYDEAIA---LEKALKLDPNNAEALLNLAELLLELGDYD 76

                         90
                 ....*....|...
gi 446735636 162 QAIELWQKVMDLN 174
Cdd:COG3063   77 EALAYLERALELD 89
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 33-174 1.31e-04

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 41.90  E-value: 1.31e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446735636  33 QAVRAEYQRQRDPLHQFASQQTPEAQLQALQDKIRANPQNSEQWALLGEYYLWqndysnsllAYRQALQLHGENAELYAA 112
Cdd:COG3914   10 AALAAAALLAAAAAAELALAAELEAAALAAALGLALLLLAALAEAAAAALLAL---------AAGEAAAAAAALLLLAAL 80

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446735636 113 LATVLYYQASQHMTAQTRAMIDKALALDSNEITALMLLASDAFMQANYAQAIELWQKVMDLN 174
Cdd:COG3914   81 LELAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALN 142
PRK11447 PRK11447
cellulose synthase subunit BcsC; Provisional
 34-175 1.56e-04

cellulose synthase subunit BcsC; Provisional


Pssm-ID: 183140 [Multi-domain]  Cd Length: 1157  Bit Score: 41.61  E-value: 1.56e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446735636   34 AVRAEYQRQR----DPLHQFASQ--------QTPEAQLQaLQDKIRANPQNSEQWALLGEYYLWQNDYSNSLLAYRQALQ 101
Cdd:PRK11447  253 AARSQLAEQQkqlaDPAFRARAQglaavdsgQGGKAIPE-LQQAVRANPKDSEALGALGQAYSQQGDRARAVAQFEKALA 331

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446735636  102 L--HGENAELYAALATVLYYQA---------SQHMTAQTRAMIDKALALDSNEITALMLLASDAFMQANYAQAIELWQKV 170
Cdd:PRK11447  332 LdpHSSNRDKWESLLKVNRYWLliqqgdaalKANNLAQAERLYQQARQVDNTDSYAVLGLGDVAMARKDYAAAERYYQQA 411


                  ....*
gi 446735636  171 MDLNS 175
Cdd:PRK11447  412 LRMDP 416
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 52-180 1.57e-04

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 41.52  E-value: 1.57e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446735636  52 QQTPEAqLQALQDKIRANPQNSEQWALLGEYYLWQNDYSNSLLAYRQALQLHGENAELYAALAtVLYYQASQHMTAQTRA 131
Cdd:COG3914  160 GRLEEA-IAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADAHSNLL-FALRQACDWEVYDRFE 237

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|
gi 446735636 132 MIDKALALDSNEITALMLLA-SDAFMQANYAQAIELWQKVMDLNSPRINR 180
Cdd:COG3914  238 ELLAALARGPSELSPFALLYlPDDDPAELLALARAWAQLVAAAAAPELPP 287
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
60-174 2.12e-04

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 40.67  E-value: 2.12e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446735636  60 QALQDKIRANPQNSEQWALLGEYYLWQNDYSNSLLAYRQALQLHGENAELYAALAtVLYYQASQHmtAQTRAMIDKALAL 139
Cdd:COG4785   60 AERIDRALALPDLAQLYYERGVAYDSLGDYDLAIADFDQALELDPDLAEAYNNRG-LAYLLLGDY--DAALEDFDRALEL 136

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 446735636 140 DSNEITALMLLASDAFMQANYAQAIELWQKVMDLN 174
Cdd:COG4785  137 DPDYAYAYLNRGIALYYLGRYELAIADLEKALELD 171
type_IV_pilW TIGR02521
type IV pilus biogenesis/stability protein PilW; Members of this family are designated PilF ...
 52-173 2.24e-04

type IV pilus biogenesis/stability protein PilW; Members of this family are designated PilF and PilW. This outer membrane protein is required both for pilus stability and for pilus function such as adherence to human cells. Members of this family contain copies of the TPR (tetratricopeptide repeat) domain.


Pssm-ID: 131573 [Multi-domain]  Cd Length: 234  Bit Score: 40.78  E-value: 2.24e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446735636   52 QQTPEAQLQALQDKIRANPQNSEQWALLGEYYLWQNDYSNSLLAYRQALQLHGENAELY--------------------- 110
Cdd:TIGR02521  44 QGDLEVAKENLDKALEHDPDDYLAYLALALYYQQLGELEKAEDSFRRALTLNPNNGDVLnnygtflcqqgkyeqamqqfe 123

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446735636  111 AALATVLYYQ------------ASQHMTAQTRAMIDKALALDSNEITALMLLASDAFMQANYAQAIELWQKVMDL 173
Cdd:TIGR02521 124 QAIEDPLYPQparslenaglcaLKAGDFDKAEKYLTRALQIDPQRPESLLELAELYYLRGQYKDARAYLERYQQT 198
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 55-173 1.00e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 39.30  E-value: 1.00e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446735636   55 PEAQLQALQDKIRANPQNSEQWALLGEYYLWQNDYSNSLLAYRQALQLHGeNAELYAALATVLyyQASQHmTAQTRAMID 134
Cdd:TIGR02917 685 TESAKKIAKSLQKQHPKAALGFELEGDLYLRQKDYPAAIQAYRKALKRAP-SSQNAIKLHRAL--LASGN-TAEAVKTLE 760

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 446735636  135 KALALDSNEITALMLLASDAFMQANYAQAIELWQKVMDL 173
Cdd:TIGR02917 761 AWLKTHPNDAVLRTALAELYLAQKDYDKAIKHYQTVVKK 799
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 26-174 1.39e-03

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 37.63  E-value: 1.39e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446735636  26 YLLSPKWQAVRAEYQRQRDPLHQFASQQTPEAQLQALQDKIRANPQNSEQWALLGEYYLWQNDYSNSLLAYRQALQLHGE 105
Cdd:COG5010    7 FDRLPLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPN 86

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446735636 106 NAELYAALAtVLYYQASQHMTAqtRAMIDKALALDSNEITALMLLASDAFMQANYAQAIELWQKVMDLN 174
Cdd:COG5010   87 NPELYYNLA-LLYSRSGDKDEA--KEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTS 152
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
59-140 1.63e-03

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 36.30  E-value: 1.63e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446735636  59 LQALQDKIRANPQNSEQWALLGEYYLWQNDYSNSlLAYRQALQLHGENAELYAALATVLYyqaSQHMTAQTRAMIDKALA 138
Cdd:COG3063   12 EEYYEKALELDPDNADALNNLGLLLLEQGRYDEA-IALEKALKLDPNNAEALLNLAELLL---ELGDYDEALAYLERALE 87


                 ..
gi 446735636 139 LD 140
Cdd:COG3063   88 LD 89
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 50-175 5.04e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 37.37  E-value: 5.04e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446735636   50 ASQQTPEAQLQALQDKIRANPQNSEQWALLGEYYLWQNDYSNSLLAYRQALQLHGENAELYAALATvlyYQASQHMTAQT 129
Cdd:TIGR02917 510 IQEGNPDDAIQRFEKVLTIDPKNLRAILALAGLYLRTGNEEEAVAWLEKAAELNPQEIEPALALAQ---YYLGKGQLKKA 586

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 446735636  130 RAMIDKALALDSNEITALMLLASDAFMQANYAQAIELWQKVMDLNS 175
Cdd:TIGR02917 587 LAILNEAADAAPDSPEAWLMLGRAQLAAGDLNKAVSSFKKLLALQP 632
PRK11788 PRK11788
tetratricopeptide repeat protein; Provisional
 118-170 6.32e-03

tetratricopeptide repeat protein; Provisional


Pssm-ID: 236983 [Multi-domain]  Cd Length: 389  Bit Score: 36.71  E-value: 6.32e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 446735636 118 YY--QASQHM----TAQTRAMIDKALALDSNEITALMLLASDAFMQANYAQAIELWQKV 170
Cdd:PRK11788 182 FYceLAQQALargdLDAARALLKKALAADPQCVRASILLGDLALAQGDYAAAIEALERV 240
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 61-179 7.68e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 36.60  E-value: 7.68e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446735636   61 ALQDKIRAN-PQNSEQWALLGEYYLWQNDYSNSLLAYRQALQLHGENaelYAALATVLYYQASQHMTAQTRAMIDKALAL 139
Cdd:TIGR02917 452 AAAKKLEKKqPDNASLHNLLGAIYLGKGDLAKAREAFEKALSIEPDF---FPAAANLARIDIQEGNPDDAIQRFEKVLTI 528

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 446735636  140 DSNEITALMLLASDAFMQANYAQAIELWQKVMDLNSPRIN 179
Cdd:TIGR02917 529 DPKNLRAILALAGLYLRTGNEEEAVAWLEKAAELNPQEIE 568
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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