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Concise Results
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outer membrane autotransporter HyxB [Escherichia coli]
Protein Classification
List of domain hits
Name
Accession
Description
Interval
E-value
autotrans_barl super family
cl36898 outer membrane autotransporter barrel domain; A number of Gram-negative bacterial proteins, ...
365-765
5.15e-52
outer membrane autotransporter barrel domain; A number of Gram-negative bacterial proteins, mostly found in pathogens and associated with virulence, contain a conserved C-terminal domain that integrates into the outer membrane and enables the N-terminal region to be delivered across the membrane. This C-terminal autotransporter domain is about 400 amino acids in length and includes the aromatic amino acid-rich OMP signal, typically ending with a Phe or Trp residue, at the extreme C-terminus. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis]
TIGR01414 :Pssm-ID: 273608 [Multi-domain]
Cd Length: 431
Bit Score: 187.21
E-value: 5.15e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 365 S T VNITKATVNT G T F as QNG T LIVDAS S E - NT L DIS G K ASG DLR V Y --- SA G SLDLINEQTAFISTGKD S ---- TL k A T G 436
Cdd:TIGR01414 6 N T LTVNGLYTGN G G F -- VMN T DLGGDN S Q t DR L VVN G N ASG TTG V V vnn IG G EGAQTGDGITLVTVNGG S daaf TL - A N G 82
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 437 TTEG G L Y Q Y D L TQG --- ADG N F Y ------------- FVKN T HK A SNA S SVIQ A M AA AP anva NLQA DTL SA R QDAV R LSE 500
Cdd:TIGR01414 83 KVDA G A Y T Y T L YKN gte DNN N W Y ltsslpdltppgq QLSP T YR A EAG S YAAN A N AA LF ---- LAEL DTL RQ R MGDL R SAA 158
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 501 N D K G - GVW IQY FGG KQKHTT - AG N A S YD LDVN GV M LGGD TRF - MTE DG SWLA G VAMSS AK G D MT T ---- MQS KG DTE GY S 573
Cdd:TIGR01414 159 R D A G n GVW ARI FGG DNHLDG d AG A A G YD QNTT GV Q LGGD ILL a GNA DG DLHV G LMAGY AK A D IK T rsyk YGG KG KVD GY G 238
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 574 FHA Y LSRQYNN G IFI D TAA Q FGHYS N TADVR lm NGG G TIKADF N T NGF G A MVKG GY TWK - D GNG LFIQ P Y A K LS ALTLE G 652
Cdd:TIGR01414 239 LGL Y GTWLQDS G AYV D GVL Q YSRFR N DVSST -- GSN G KVSGKY N S NGF T A SLEA GY RYN l G GNG WYVE P Q A Q LS YFGVS G 316
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 653 V DY QL - NG VD V HSDSYN S VL G EA G T RVGY D F AV G N - AT VKPYL NLAA L N EF SD G NK VR LGDESVNASID G AAFRV G A GV Q 730
Cdd:TIGR01414 317 D DY KE s NG TR V LGGGGD S LQ G RL G L RVGY Q F DL G T g RA VKPYL KANV L H EF KG G TG VR VNGVTIRNDFS G TRAEY G V GV N 396
410 420 430
....*....|....*....|....*....|....*
gi 446720757 731 A D I TK N MGA YA SL DY T KG DDIENPL QG VV G INVTW 765
Cdd:TIGR01414 397 A K I KD N LSL YA DV DY Q KG GKKYTDN QG NL G VRYSF 431
PL_Passenger_AT super family
cl00185 Pertactin-like passenger domains (virulence factors) of autotransporter proteins of the type V ...
251-461
1.69e-07
Pertactin-like passenger domains (virulence factors) of autotransporter proteins of the type V secretion system. Autotransporters are proteins used by Gram-negative bacteria to transport proteins across their outer membranes. The C-terminal (beta) domain of autotransporters forms a pore in the outer membrane through which the N-terminal passenger domain is transported. Following transport, the passenger domain is generally cleaved by an outer membrane protease with the passenger domain either remaining in contact with the surface via a noncovalent interaction with the beta domain or cleaved to release a soluble protein. These proteins are highly diverse and perform a variety of functions that promote virulence, including catalyzing proteolysis, serving as an adhesin, mediating actin-promoted motility, or serving as a cytotoxin. Proteins in this family share similarity in the C-terminal region of the passenger domain as seen in the pertactin structure P.69, a Bordetella pertussis agglutinogen responsible for human pertussis. The P.69 protein consists of a 16-stranded parallel beta-helix with a V-shaped cross-section, and is one of the largest beta-helix known to date.
cd01343 :Pssm-ID: 469645 [Multi-domain]
Cd Length: 233
Bit Score: 52.74
E-value: 1.69e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 251 SA S AQ G AGS A TQ N LN L SVADSTI Y SDVLA L SE se NSASTTT N V N MNV A R SY WEGNAYTFNSGDKA G SDLDIN ------ L S 324
Cdd:cd01343 3 LV S DG G NIT A GD N AQ L TLGGGAL Y GSSVT L TN -- GAVLDAG N A N LSA A A SY ATLSGSNIRGTVVL G AGQPLQ alaell L G 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 325 DSSV W K G KVS G A g D A S VSL QNG SVW NV TG S S T V DA L AVKDS TV --- NITKATV NT G T FASQN G T ---- LIV D ASSENT -- 395
Cdd:cd01343 81 GNAA W T G AIQ G L - N A T VSL NLN SVW TL TG D S N V NN L TLNGG TV dfn GPSAGKF NT L T VNTLS G N gtfv MRT D LAGGQG dk 159
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446720757 396 L DIS G K A S GD -- L R V YSA G SLDLINEQTAFI ST G K DSTL --- K A T GT TEG G L Y Q Y D L TQGAD GN FYFVKNT 461
Cdd:cd01343 160 L VVT G S A T GD fn L L V VNT G KEPTSGLNLTLV ST P K GGDA eft L A N GT VDL G A Y R Y T L VKDGN GN WTLTGPK 230
FhaB super family
cl27105 Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, ...
9-416
4.41e-04
Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, secretion, and vesicular transport];
COG3210 :Pssm-ID: 442443 [Multi-domain]
Cd Length: 1698
Bit Score: 43.99
E-value: 4.41e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 9 RSALATAIVM A LSAPAFATDSTVSTDPV T L N TEKTTLDQDVVI N GDNKI T AVTIETSDSDKDLNV T FG G HDIT A ASTVNQ 88
Cdd:COG3210 308 GTGVLGGGTA A GITTTNTVGGNGDGNNT T A N SGAGLVSGGTGG N NGTTG T GAGSGLTGTGNGGGL T TA G AGTV A STVGTA 387
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 89 DFVE G VKV S GNKNVVINATDSTITAQGE G TYVRTAMVIDS T GDV V VNGGNFVAKNEKGSATGISLEA T T G NN L TL N GTTI 168
Cdd:COG3210 388 TAST G NAS S TTVLGSGSLATGNTGTTIA G NGGSANAGGFT T TGG V LGITGNGTVTGGTIGGLTGSGT T N G AG L SG N TDVS 467
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 169 NAQGNKSYSNG - ST A IFAQK G NLLQGFDGDATD N ITLA D S N I I NG G IET I VTA G NKT G IH T VNLNIK DG SVIGAANNKQ T 247
Cdd:COG3210 468 GTGTVTNSAGN t TS A TTLAG G GIGTVTTNATIS N NAGG D A N G I AT G LTG I TAG G GGG G NA T SGGTGG DG TTLSGSGLTT T 547
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 248 IYAS AS AQG A G S ATQNL N LSVADSTIYSDVL A LS e SE NS A S T T TNVNM N VARSYWEGNAYTFNSGDKAGSDLDINLSDSS 327
Cdd:COG3210 548 VSGG AS GTT A A S GSNTA N TLGVLAATGGTSN A TT - AG NS T S A T GGTGT N SGGTVLSIGTGSAGATGTITLGAGTSGAGAN 626
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 328 VWK G KVSGA G D A SVSLQN G SVWNV TG SSTVDALAVKDSTVNITKATVN TGT FA S QNGTLIVDASSENTLDISGKAS G DLR 407
Cdd:COG3210 627 ATG G GAGLT G S A VGAALS G TGSGT TG TASANGSNTTGVNTAGGTGGGT TGT VT S GATGGTTGTTLNAATGGTLNNA G NTL 706
....*....
gi 446720757 408 VY S A GS LDL 416
Cdd:COG3210 707 TI S T GS ITV 715
Name
Accession
Description
Interval
E-value
autotrans_barl
TIGR01414 outer membrane autotransporter barrel domain; A number of Gram-negative bacterial proteins, ...
365-765
5.15e-52
outer membrane autotransporter barrel domain; A number of Gram-negative bacterial proteins, mostly found in pathogens and associated with virulence, contain a conserved C-terminal domain that integrates into the outer membrane and enables the N-terminal region to be delivered across the membrane. This C-terminal autotransporter domain is about 400 amino acids in length and includes the aromatic amino acid-rich OMP signal, typically ending with a Phe or Trp residue, at the extreme C-terminus. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis]
Pssm-ID: 273608 [Multi-domain]
Cd Length: 431
Bit Score: 187.21
E-value: 5.15e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 365 S T VNITKATVNT G T F as QNG T LIVDAS S E - NT L DIS G K ASG DLR V Y --- SA G SLDLINEQTAFISTGKD S ---- TL k A T G 436
Cdd:TIGR01414 6 N T LTVNGLYTGN G G F -- VMN T DLGGDN S Q t DR L VVN G N ASG TTG V V vnn IG G EGAQTGDGITLVTVNGG S daaf TL - A N G 82
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 437 TTEG G L Y Q Y D L TQG --- ADG N F Y ------------- FVKN T HK A SNA S SVIQ A M AA AP anva NLQA DTL SA R QDAV R LSE 500
Cdd:TIGR01414 83 KVDA G A Y T Y T L YKN gte DNN N W Y ltsslpdltppgq QLSP T YR A EAG S YAAN A N AA LF ---- LAEL DTL RQ R MGDL R SAA 158
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 501 N D K G - GVW IQY FGG KQKHTT - AG N A S YD LDVN GV M LGGD TRF - MTE DG SWLA G VAMSS AK G D MT T ---- MQS KG DTE GY S 573
Cdd:TIGR01414 159 R D A G n GVW ARI FGG DNHLDG d AG A A G YD QNTT GV Q LGGD ILL a GNA DG DLHV G LMAGY AK A D IK T rsyk YGG KG KVD GY G 238
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 574 FHA Y LSRQYNN G IFI D TAA Q FGHYS N TADVR lm NGG G TIKADF N T NGF G A MVKG GY TWK - D GNG LFIQ P Y A K LS ALTLE G 652
Cdd:TIGR01414 239 LGL Y GTWLQDS G AYV D GVL Q YSRFR N DVSST -- GSN G KVSGKY N S NGF T A SLEA GY RYN l G GNG WYVE P Q A Q LS YFGVS G 316
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 653 V DY QL - NG VD V HSDSYN S VL G EA G T RVGY D F AV G N - AT VKPYL NLAA L N EF SD G NK VR LGDESVNASID G AAFRV G A GV Q 730
Cdd:TIGR01414 317 D DY KE s NG TR V LGGGGD S LQ G RL G L RVGY Q F DL G T g RA VKPYL KANV L H EF KG G TG VR VNGVTIRNDFS G TRAEY G V GV N 396
410 420 430
....*....|....*....|....*....|....*
gi 446720757 731 A D I TK N MGA YA SL DY T KG DDIENPL QG VV G INVTW 765
Cdd:TIGR01414 397 A K I KD N LSL YA DV DY Q KG GKKYTDN QG NL G VRYSF 431
AidA
COG3468 Autotransporter adhesin AidA [Cell wall/membrane/envelope biogenesis, Intracellular ...
11-765
2.70e-41
Autotransporter adhesin AidA [Cell wall/membrane/envelope biogenesis, Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 442691 [Multi-domain]
Cd Length: 846
Bit Score: 162.42
E-value: 2.70e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 11 ALATAIVM A L S APAF A TDSTVS T DPVTLNTEKTTLDQDVVIN G DNKITAVTIETSDSDKDLNV T F GG HDITAA S TVNQDF 90
Cdd:COG3468 62 GAGGGGGG A G S GGGL A GAGSGG T GGNSTGGGGGNSGTGGTGG G GGGGGSGNGGGGGGGGGGGG T G GG GGGGTG S AGGGGG 141
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 91 VE G VKVSGNKNVVIN A TDS T ITAQ G EGTYVRT A MVIDST G DVVVN G GNFVAKNEK G SAT G ISLEATTGNNLTLN G TTIN A 170
Cdd:COG3468 142 GG G GGTGVGGTGAAA A GGG T GSGG G GSGGGGG A GGGGGG G AGGSG G AGSTGSGAG G GGG G SGGGGGAAGTGGGG G GGGG A 221
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 171 Q G NKSYSNGSTAIFA q KGNLLQ G FD G DATDNITLADSNIIN GG IETIVTA G NKT G IHTVNLNIKD G SVI GA ANNKQTIY A 250
Cdd:COG3468 222 G G ATGGAGSGGNTGG - GVGGGG G SA G GTGGGGLTGGGAAGT GG GGGGTGT G SGG G GGGGANGGGS G GGG GA SGTGGGGT A 300
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 251 S ASAQ G A G SATQNLNLSVADSTIYSDVLALSESENSASTT T NV N MNVARSYWE G N A YTFNS G DKA G SDLDINLSDSSVWK 330
Cdd:COG3468 301 S TGGG G G G GGGNGGGGGGGSNAGGGSGGGGGGGGGGGGGG T TL N GAGSAGGGT G A A LAGTG G SGS G GGGGGGSGGGGGAG 380
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 331 G KVSGA G DAS V SLQNGSVWNVTGSSTVDALAVKDSTVNITKATVNT G TFASQ NGTL IV ------ D A S SENT L DIS G KA SG 404
Cdd:COG3468 381 G GGANT G SDG V GTGLTTGGTGNNGGGGVGGGGGGGLTLTGGTLTVN G NYTGN NGTL VL ntvlgd D N S PTDR L VVN G NT SG 460
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 405 DLR V Y --- SA G SLDLINEQTAFISTGKD S -- TLKAT G TTEG G L Y Q Y D L T QG ---- A DGN F Y FVKNTHKASNASS V IQAMA 475
Cdd:COG3468 461 TTG V R vnn AG G LGAQTVNGIEVVEVNGA S dg AFTLG G RVVA G A Y E Y T L Y QG gsgg D DGN W Y LRSTLTPPDPPTP V YRPEV 540
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 476 AA ----- P A NVANLQAD TL SA R QDAV R L --- S E N D KG G V W IQYF GG KQKHTTA - G NAS YD LDVN G VM LGGD TRFM - TED G 545
Cdd:COG3468 541 PS ylanp A A ANGLFELG TL HD R LGER R Y tdt G E S D NS G A W LRVE GG HNRSRDS s G QLD YD SNRY G LQ LGGD LLQW e DGG G 620
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 546 SWLA GV AMSSAK GD MTT ----- MQS KGD TE GYS FHA Y LSRQY NNG IFI D TAA Q FGHYS N TADVRLMN G ggt IKADFNT NG 620
Cdd:COG3468 621 RLHV GV MAGYGN GD SDV rsrat GTG KGD VD GYS LGL Y GTWYG NNG FYV D GVL Q YSWFD N DVSSDDLG G --- VTGSYDG NG 697
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 621 FG A MVKG GY TW K D G N G LFIQ P Y A K L SALTLEGV D YQL - NG VD V HS D SYN S VL G EA G T R V GY D F AVGNA - TVK PYL NLAA L 698
Cdd:COG3468 698 YS A SLEA GY PF K L G E G WSLE P Q A Q L IYQGVDFD D FTD s NG TR V SG D DGD S LQ G RL G L R L GY E F HWDDG r ALQ PYL EANW L 777
730 740 750 760 770 780
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446720757 699 N EF SDG N K V RLGDE S VNASID G AAFRV G A GV QADIT KN MGA Y ASLD Y TK G D D -- IENPLQ G VV G INVTW 765
Cdd:COG3468 778 H EF LGD N S V TVNGV S FSQDGS G TWGEL G L GV TGQLN KN LSL Y GDVG Y QT G L D gy DSSDTS G NL G VRYSF 846
Autotransporter
pfam03797 Autotransporter beta-domain; Secretion of protein products occurs by a number of different ...
506-744
4.34e-37
Autotransporter beta-domain; Secretion of protein products occurs by a number of different pathways in bacteria. One of these pathways known as the type V pathway was first described for the IgA1 protease. The protein component that mediates secretion through the outer membrane is contained within the secreted protein itself, hence the proteins secreted in this way are called autotransporters. This family corresponds to the presumed integral membrane beta-barrel domain that transports the protein. This domain is found at the C terminus of the proteins it occurs in. The N terminus contains the variable passenger domain that is translocated across the membrane. Once the passenger domain is exported it is cleaved auto-catalytically in some proteins, in others a different protease is used and in some cases no cleavage occurs.
Pssm-ID: 461054 [Multi-domain]
Cd Length: 255
Bit Score: 139.83
E-value: 4.34e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 506 VW IQY FGG KQ K H - TTA G N A S YD L D VN G VML G G D T R F mte DGSWLA GVA M -- S SAKG D MTTMQSK GD TEG YS FHA Y LSRQY 582
Cdd:pfam03797 1 VW ARG FGG RG K Q d GDG G A A G YD A D TG G LQV G A D Y R L --- GDNLRL GVA F gy S RSDA D VDGRGGS GD SDS YS LGL Y GTYYG 77
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 583 NN G IFI D TAAQF G HYS N TADVRLMN GG -- G T I K A D FNT NGFGA MVKG GY TWKD G N G LFIQ P Y A K L SALT L EGVDYQLN G - 659
Cdd:pfam03797 78 DG G WYL D GGLGY G WHD N DTRRSVDL GG fs E T A K G D YDG NGFGA SLEA GY RFAL G G G WTLE P F A G L AYVR L RLDGFTES G g 157
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 660 --- VD V H S D SY N S VL G EA G T R VG Y D F AV G NA T VK PY LN L AALN EF S D GNK V RLGD ---------- ESVN A SIDGAAFRV G 726
Cdd:pfam03797 158 aaa LS V D S Q SY D S LT G RL G L R LS Y T F DL G GG T LT PY AR L GWRH EF G D DDP V TTAA faglsgagsf TVAG A DLARDSLEL G 237
250
....*....|....*...
gi 446720757 727 AG VQ A DITK N MGA YA SL D 744
Cdd:pfam03797 238 AG LS A QLSD N LSL YA NY D 255
Autotransporter
smart00869 Autotransporter beta-domain; Secretion of protein products occurs by a number of different ...
508-753
7.53e-30
Autotransporter beta-domain; Secretion of protein products occurs by a number of different pathways in bacteria. One of these pathways known as the type IV pathway was first described for the IgA1 protease. The protein component that mediates secretion through the outer membrane is contained within the secreted protein itself, hence the proteins secreted in this way are called autotransporters. This family corresponds to the presumed integral membrane beta-barrel domain that transports the protein. This domain is found at the C-terminus of the proteins it occurs in. The N-terminus contains the variable passenger domain that is translocated across the membrane. Once the passenger domain is exported it is cleaved auto-catalytically in some proteins, in others a different peptidase is used and in some cases no cleavage occurs.
Pssm-ID: 214872 [Multi-domain]
Cd Length: 268
Bit Score: 119.21
E-value: 7.53e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 508 IQYF GG KQKH --- TTA G N A SY D L D VN G VM LG G D T R F m TED G SWLA G V A MSSAKGDMTT ---- MQS KGD TEG Y SFHA Y LSR 580
Cdd:smart00869 1 GRGL GG FLRQ dss GSG G S A GF D Y D SY G LQ LG A D Y R L - SDN G NLSL G F A AGYGNSKVDF sgnk GSG KGD VDS Y GLGL Y AGY 79
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 581 QYN NG IFI D TAAQF G HYS N TADVRLMN GG - G TI K ADFNTN G F GA MVKG GY TWKD G N GL FIQ P Y A K L SALTLEGVDYQLN G 659
Cdd:smart00869 80 SLG NG LYL D AQLGY G RSD N DTKRKVTL GG a G RA K GSYDGT G Y GA SLEA GY RFYL G G GL TLT P F A G L AYSRVRQDGFTES G 159
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 660 VD ----- V H S D S YN S VLGEA G T R VG Y DF A V G NAT - VK PYL N LA ALNE F S D G N K V RLG -------- DESVNASI D GA A FRV 725
Cdd:smart00869 160 GG afgls V D S Q S LD S LSLPL G L R LE Y RL A L G DGA t LT PYL R LA YVHD F Y D D N P V VTA sllgsgas FTTSGTDL D RN A AEL 239
250 260
....*....|....*....|....*...
gi 446720757 726 G A G VQ A DITKNMGAYASL D YTK G DDIEN 753
Cdd:smart00869 240 G L G LS A KLSNGLSLSLNY D GEF G GSSRS 267
PL1_Passenger_AT
cd01343 Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 1, of ...
251-461
1.69e-07
Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 1, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of Neisseria and Haemophilus IgA1 proteases, SPATEs (serine protease autotransporters secreted by Enterobacteriaceae), Bordetella pertacins, and nonprotease autotransporters, TibA and similar AIDA-like proteins.
Pssm-ID: 238653 [Multi-domain]
Cd Length: 233
Bit Score: 52.74
E-value: 1.69e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 251 SA S AQ G AGS A TQ N LN L SVADSTI Y SDVLA L SE se NSASTTT N V N MNV A R SY WEGNAYTFNSGDKA G SDLDIN ------ L S 324
Cdd:cd01343 3 LV S DG G NIT A GD N AQ L TLGGGAL Y GSSVT L TN -- GAVLDAG N A N LSA A A SY ATLSGSNIRGTVVL G AGQPLQ alaell L G 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 325 DSSV W K G KVS G A g D A S VSL QNG SVW NV TG S S T V DA L AVKDS TV --- NITKATV NT G T FASQN G T ---- LIV D ASSENT -- 395
Cdd:cd01343 81 GNAA W T G AIQ G L - N A T VSL NLN SVW TL TG D S N V NN L TLNGG TV dfn GPSAGKF NT L T VNTLS G N gtfv MRT D LAGGQG dk 159
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446720757 396 L DIS G K A S GD -- L R V YSA G SLDLINEQTAFI ST G K DSTL --- K A T GT TEG G L Y Q Y D L TQGAD GN FYFVKNT 461
Cdd:cd01343 160 L VVT G S A T GD fn L L V VNT G KEPTSGLNLTLV ST P K GGDA eft L A N GT VDL G A Y R Y T L VKDGN GN WTLTGPK 230
PRK14849
PRK14849 autotransporter barrel domain-containing lipoprotein;
82-765
5.03e-05
autotransporter barrel domain-containing lipoprotein;
Pssm-ID: 184851 [Multi-domain]
Cd Length: 1806
Bit Score: 47.04
E-value: 5.03e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 82 A A S TVN QDFVEGVKVS G NK N vv I N A T DS T ITAQ G EGTYVRTAMV I DSTGD V VVNGGNFVAKNEKGSATGIS L EAT TG --- 158
Cdd:PRK14849 1099 G A L TVN KGGISQGELT G GG N -- L N V T GG T LAIE G LNARYNALTS I SPNAE V SLDNTQGLGRGNIANDGLLT L KNV TG elr 1176
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 159 N NLTLN G TTINAQGNKSYSN G STAI F AQKG N LLQ G FDGDATDNIT L A D SNI IN G G IE TI V T AGNKTGI H TVN lnikdgsv 238
Cdd:PRK14849 1177 N SISGK G IVSATARTDVELD G DNSR F VGQF N IDT G SALSVNEQKN L G D ASV IN N G LL TI S T ERSWAMT H SIS -------- 1248
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 239 igaannkqtiy A S ASAQGA G SATQN LN lsv A DS TI Y SDVLALSES E NSASTTTNV NM nvarsywegnaytfnsgdkag SD 318
Cdd:PRK14849 1249 ----------- G S GDVTKL G TGILT LN --- N DS AA Y QGTTDIVGG E IAFGSDSAI NM --------------------- AS 1293
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 319 LD IN LSD S S V WK G K V SG AGD AS V --------------- S L Q NG SV -- W N VT G SSTVDA L A V KDST vnitka T V N T G t FAS 381
Cdd:PRK14849 1294 QH IN IHN S G V MS G N V TT AGD VN V mpggtlrvakttigg N L E NG GT vq M N SE G GKPGNV L T V NGNY ------ T G N N G - LMT 1366
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 382 Q N G TL IV D A S SENTLDIS G KAS G DL RV y SAGSLDLINE QT A ---- F I ST G KD S TLK --- A TGT T E G G L Y Q Y D L TQ G A --- 451
Cdd:PRK14849 1367 F N A TL GG D N S PTDKMNVK G DTQ G NT RV - RVDNIGGVGA QT V ngie L I EV G GN S AGN fal T TGT V E A G A Y V Y T L AK G K gnd 1445
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 452 DG N F Y FVKNTHKAS ------------------------ N A S S V I QAM AAA PANVANLQA D T L SAR Q DAVR L - S ENDKGGV 506
Cdd:PRK14849 1446 EK N W Y LTSKWDGVT ppdtpdpinnppvvdpegpsvyrp E A G S Y I SNI AAA NSLFSHRLH D R L GEP Q YIDS L h S QGSASSM 1525
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 507 W IQYF GG KQK h TT AG NASYDLDV N G -- VM LGGD TRFMTEDGS -- W LA GV AM ------ S SAKGDMTTMQ S K G DTE GYS FHA 576
Cdd:PRK14849 1526 W MRHV GG HER - SR AG DGQLNTQA N R yv LQ LGGD LAQWSSNAQ dr W HL GV MA gyanqh S NTQSNRVGYK S D G RIS GYS AGL 1604
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 577 Y LSRQY N N ---- G IFI D TA A QFGHYS N T advrl MNGGGTIKA D FNTN G FG A M V K GGYT WKD G --------- N GLFI QP Y A 643
Cdd:PRK14849 1605 Y ATWYQ N D ankt G AYV D SW A LYNWFD N S ----- VSSDNRSAD D YDSR G VT A S V E GGYT FEA G tfsgsegtl N TWYV QP Q A 1679
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 644 KLSALTLEGV D Y - QLN G VDVHSDSYNS V LGEA G TRVGYDFAV ----- GNATVK PY LNLAAL N E f S DGNK V RLGDES V NAS 717
Cdd:PRK14849 1680 QITWMGVKDS D H t RKD G TRIETEGDGN V QTRL G VKTYLNSHH qrddg KQREFQ PY IEANWI N N - S KVYA V KMNGQT V GRE 1758
730 740 750 760
....*....|....*....|....*....|....*....|....*...
gi 446720757 718 IDGAAFR V GA GV Q A DITK N MGAYASLDYTK GD DIENPL QG VV G INVT W 765
Cdd:PRK14849 1759 GARNLGE V RT GV E A KVNN N LSLWGNVGVQL GD KGYSDT QG ML G VKYS W 1806
FhaB
COG3210 Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, ...
9-416
4.41e-04
Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 442443 [Multi-domain]
Cd Length: 1698
Bit Score: 43.99
E-value: 4.41e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 9 RSALATAIVM A LSAPAFATDSTVSTDPV T L N TEKTTLDQDVVI N GDNKI T AVTIETSDSDKDLNV T FG G HDIT A ASTVNQ 88
Cdd:COG3210 308 GTGVLGGGTA A GITTTNTVGGNGDGNNT T A N SGAGLVSGGTGG N NGTTG T GAGSGLTGTGNGGGL T TA G AGTV A STVGTA 387
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 89 DFVE G VKV S GNKNVVINATDSTITAQGE G TYVRTAMVIDS T GDV V VNGGNFVAKNEKGSATGISLEA T T G NN L TL N GTTI 168
Cdd:COG3210 388 TAST G NAS S TTVLGSGSLATGNTGTTIA G NGGSANAGGFT T TGG V LGITGNGTVTGGTIGGLTGSGT T N G AG L SG N TDVS 467
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 169 NAQGNKSYSNG - ST A IFAQK G NLLQGFDGDATD N ITLA D S N I I NG G IET I VTA G NKT G IH T VNLNIK DG SVIGAANNKQ T 247
Cdd:COG3210 468 GTGTVTNSAGN t TS A TTLAG G GIGTVTTNATIS N NAGG D A N G I AT G LTG I TAG G GGG G NA T SGGTGG DG TTLSGSGLTT T 547
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 248 IYAS AS AQG A G S ATQNL N LSVADSTIYSDVL A LS e SE NS A S T T TNVNM N VARSYWEGNAYTFNSGDKAGSDLDINLSDSS 327
Cdd:COG3210 548 VSGG AS GTT A A S GSNTA N TLGVLAATGGTSN A TT - AG NS T S A T GGTGT N SGGTVLSIGTGSAGATGTITLGAGTSGAGAN 626
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 328 VWK G KVSGA G D A SVSLQN G SVWNV TG SSTVDALAVKDSTVNITKATVN TGT FA S QNGTLIVDASSENTLDISGKAS G DLR 407
Cdd:COG3210 627 ATG G GAGLT G S A VGAALS G TGSGT TG TASANGSNTTGVNTAGGTGGGT TGT VT S GATGGTTGTTLNAATGGTLNNA G NTL 706
....*....
gi 446720757 408 VY S A GS LDL 416
Cdd:COG3210 707 TI S T GS ITV 715
34
PHA02584 long tail fiber, proximal subunit; Provisional
46-277
7.60e-04
long tail fiber, proximal subunit; Provisional
Pssm-ID: 222890 [Multi-domain]
Cd Length: 1229
Bit Score: 43.21
E-value: 7.60e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 46 D Q D VVI NG DNKI T AV T IETSDSDKDLNV TFGG HDITAASTVN Q DFVE G VK V SGNKNV ---- VI N A T DST I TAQGE GT YVR 121
Cdd:PHA02584 902 D I D QTV NG SLTF T KN T NLSAPLVSSSTA TFGG SVTANSTLTT Q NTSN G TV V VVDETS iafy SQ N N T TGN I VFNID GT VDP 981
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 122 TAMV id ST G D ----- V VV NG GNFV A KNEKGSA T GISLE A T TG NNLTL N GTTINAQGNKSYSNGSTAIFAQ K GNLLQ gfdg 196
Cdd:PHA02584 982 INVN -- AN G T lnatg V AT NG RAVY A EGGGIAR T NNAAR A I TG GFTIR N DGSTTVFLLTAAGDQTGGFNGL K SLIIN ---- 1055
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 197 D A TDNI T LA D SN IIN G G IETI vtagnk T G IH TVN LN I K dgsvigaann K Q TIY AS ASAQGAGSATQNLNLSVA DS TI Y SD 276
Cdd:PHA02584 1056 N A NGQV T IN D NY IIN A G GTIM ------ S G GL TVN SR I R ---------- S Q GTK AS YTRAPTADTVGFWSVDIN DS AT Y NQ 1119
.
gi 446720757 277 V 277
Cdd:PHA02584 1120 F 1120
Name
Accession
Description
Interval
E-value
autotrans_barl
TIGR01414 outer membrane autotransporter barrel domain; A number of Gram-negative bacterial proteins, ...
365-765
5.15e-52
outer membrane autotransporter barrel domain; A number of Gram-negative bacterial proteins, mostly found in pathogens and associated with virulence, contain a conserved C-terminal domain that integrates into the outer membrane and enables the N-terminal region to be delivered across the membrane. This C-terminal autotransporter domain is about 400 amino acids in length and includes the aromatic amino acid-rich OMP signal, typically ending with a Phe or Trp residue, at the extreme C-terminus. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis]
Pssm-ID: 273608 [Multi-domain]
Cd Length: 431
Bit Score: 187.21
E-value: 5.15e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 365 S T VNITKATVNT G T F as QNG T LIVDAS S E - NT L DIS G K ASG DLR V Y --- SA G SLDLINEQTAFISTGKD S ---- TL k A T G 436
Cdd:TIGR01414 6 N T LTVNGLYTGN G G F -- VMN T DLGGDN S Q t DR L VVN G N ASG TTG V V vnn IG G EGAQTGDGITLVTVNGG S daaf TL - A N G 82
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 437 TTEG G L Y Q Y D L TQG --- ADG N F Y ------------- FVKN T HK A SNA S SVIQ A M AA AP anva NLQA DTL SA R QDAV R LSE 500
Cdd:TIGR01414 83 KVDA G A Y T Y T L YKN gte DNN N W Y ltsslpdltppgq QLSP T YR A EAG S YAAN A N AA LF ---- LAEL DTL RQ R MGDL R SAA 158
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 501 N D K G - GVW IQY FGG KQKHTT - AG N A S YD LDVN GV M LGGD TRF - MTE DG SWLA G VAMSS AK G D MT T ---- MQS KG DTE GY S 573
Cdd:TIGR01414 159 R D A G n GVW ARI FGG DNHLDG d AG A A G YD QNTT GV Q LGGD ILL a GNA DG DLHV G LMAGY AK A D IK T rsyk YGG KG KVD GY G 238
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 574 FHA Y LSRQYNN G IFI D TAA Q FGHYS N TADVR lm NGG G TIKADF N T NGF G A MVKG GY TWK - D GNG LFIQ P Y A K LS ALTLE G 652
Cdd:TIGR01414 239 LGL Y GTWLQDS G AYV D GVL Q YSRFR N DVSST -- GSN G KVSGKY N S NGF T A SLEA GY RYN l G GNG WYVE P Q A Q LS YFGVS G 316
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 653 V DY QL - NG VD V HSDSYN S VL G EA G T RVGY D F AV G N - AT VKPYL NLAA L N EF SD G NK VR LGDESVNASID G AAFRV G A GV Q 730
Cdd:TIGR01414 317 D DY KE s NG TR V LGGGGD S LQ G RL G L RVGY Q F DL G T g RA VKPYL KANV L H EF KG G TG VR VNGVTIRNDFS G TRAEY G V GV N 396
410 420 430
....*....|....*....|....*....|....*
gi 446720757 731 A D I TK N MGA YA SL DY T KG DDIENPL QG VV G INVTW 765
Cdd:TIGR01414 397 A K I KD N LSL YA DV DY Q KG GKKYTDN QG NL G VRYSF 431
AidA
COG3468 Autotransporter adhesin AidA [Cell wall/membrane/envelope biogenesis, Intracellular ...
11-765
2.70e-41
Autotransporter adhesin AidA [Cell wall/membrane/envelope biogenesis, Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 442691 [Multi-domain]
Cd Length: 846
Bit Score: 162.42
E-value: 2.70e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 11 ALATAIVM A L S APAF A TDSTVS T DPVTLNTEKTTLDQDVVIN G DNKITAVTIETSDSDKDLNV T F GG HDITAA S TVNQDF 90
Cdd:COG3468 62 GAGGGGGG A G S GGGL A GAGSGG T GGNSTGGGGGNSGTGGTGG G GGGGGSGNGGGGGGGGGGGG T G GG GGGGTG S AGGGGG 141
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 91 VE G VKVSGNKNVVIN A TDS T ITAQ G EGTYVRT A MVIDST G DVVVN G GNFVAKNEK G SAT G ISLEATTGNNLTLN G TTIN A 170
Cdd:COG3468 142 GG G GGTGVGGTGAAA A GGG T GSGG G GSGGGGG A GGGGGG G AGGSG G AGSTGSGAG G GGG G SGGGGGAAGTGGGG G GGGG A 221
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 171 Q G NKSYSNGSTAIFA q KGNLLQ G FD G DATDNITLADSNIIN GG IETIVTA G NKT G IHTVNLNIKD G SVI GA ANNKQTIY A 250
Cdd:COG3468 222 G G ATGGAGSGGNTGG - GVGGGG G SA G GTGGGGLTGGGAAGT GG GGGGTGT G SGG G GGGGANGGGS G GGG GA SGTGGGGT A 300
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 251 S ASAQ G A G SATQNLNLSVADSTIYSDVLALSESENSASTT T NV N MNVARSYWE G N A YTFNS G DKA G SDLDINLSDSSVWK 330
Cdd:COG3468 301 S TGGG G G G GGGNGGGGGGGSNAGGGSGGGGGGGGGGGGGG T TL N GAGSAGGGT G A A LAGTG G SGS G GGGGGGSGGGGGAG 380
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 331 G KVSGA G DAS V SLQNGSVWNVTGSSTVDALAVKDSTVNITKATVNT G TFASQ NGTL IV ------ D A S SENT L DIS G KA SG 404
Cdd:COG3468 381 G GGANT G SDG V GTGLTTGGTGNNGGGGVGGGGGGGLTLTGGTLTVN G NYTGN NGTL VL ntvlgd D N S PTDR L VVN G NT SG 460
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 405 DLR V Y --- SA G SLDLINEQTAFISTGKD S -- TLKAT G TTEG G L Y Q Y D L T QG ---- A DGN F Y FVKNTHKASNASS V IQAMA 475
Cdd:COG3468 461 TTG V R vnn AG G LGAQTVNGIEVVEVNGA S dg AFTLG G RVVA G A Y E Y T L Y QG gsgg D DGN W Y LRSTLTPPDPPTP V YRPEV 540
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 476 AA ----- P A NVANLQAD TL SA R QDAV R L --- S E N D KG G V W IQYF GG KQKHTTA - G NAS YD LDVN G VM LGGD TRFM - TED G 545
Cdd:COG3468 541 PS ylanp A A ANGLFELG TL HD R LGER R Y tdt G E S D NS G A W LRVE GG HNRSRDS s G QLD YD SNRY G LQ LGGD LLQW e DGG G 620
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 546 SWLA GV AMSSAK GD MTT ----- MQS KGD TE GYS FHA Y LSRQY NNG IFI D TAA Q FGHYS N TADVRLMN G ggt IKADFNT NG 620
Cdd:COG3468 621 RLHV GV MAGYGN GD SDV rsrat GTG KGD VD GYS LGL Y GTWYG NNG FYV D GVL Q YSWFD N DVSSDDLG G --- VTGSYDG NG 697
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 621 FG A MVKG GY TW K D G N G LFIQ P Y A K L SALTLEGV D YQL - NG VD V HS D SYN S VL G EA G T R V GY D F AVGNA - TVK PYL NLAA L 698
Cdd:COG3468 698 YS A SLEA GY PF K L G E G WSLE P Q A Q L IYQGVDFD D FTD s NG TR V SG D DGD S LQ G RL G L R L GY E F HWDDG r ALQ PYL EANW L 777
730 740 750 760 770 780
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446720757 699 N EF SDG N K V RLGDE S VNASID G AAFRV G A GV QADIT KN MGA Y ASLD Y TK G D D -- IENPLQ G VV G INVTW 765
Cdd:COG3468 778 H EF LGD N S V TVNGV S FSQDGS G TWGEL G L GV TGQLN KN LSL Y GDVG Y QT G L D gy DSSDTS G NL G VRYSF 846
Autotransporter
pfam03797 Autotransporter beta-domain; Secretion of protein products occurs by a number of different ...
506-744
4.34e-37
Autotransporter beta-domain; Secretion of protein products occurs by a number of different pathways in bacteria. One of these pathways known as the type V pathway was first described for the IgA1 protease. The protein component that mediates secretion through the outer membrane is contained within the secreted protein itself, hence the proteins secreted in this way are called autotransporters. This family corresponds to the presumed integral membrane beta-barrel domain that transports the protein. This domain is found at the C terminus of the proteins it occurs in. The N terminus contains the variable passenger domain that is translocated across the membrane. Once the passenger domain is exported it is cleaved auto-catalytically in some proteins, in others a different protease is used and in some cases no cleavage occurs.
Pssm-ID: 461054 [Multi-domain]
Cd Length: 255
Bit Score: 139.83
E-value: 4.34e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 506 VW IQY FGG KQ K H - TTA G N A S YD L D VN G VML G G D T R F mte DGSWLA GVA M -- S SAKG D MTTMQSK GD TEG YS FHA Y LSRQY 582
Cdd:pfam03797 1 VW ARG FGG RG K Q d GDG G A A G YD A D TG G LQV G A D Y R L --- GDNLRL GVA F gy S RSDA D VDGRGGS GD SDS YS LGL Y GTYYG 77
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 583 NN G IFI D TAAQF G HYS N TADVRLMN GG -- G T I K A D FNT NGFGA MVKG GY TWKD G N G LFIQ P Y A K L SALT L EGVDYQLN G - 659
Cdd:pfam03797 78 DG G WYL D GGLGY G WHD N DTRRSVDL GG fs E T A K G D YDG NGFGA SLEA GY RFAL G G G WTLE P F A G L AYVR L RLDGFTES G g 157
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 660 --- VD V H S D SY N S VL G EA G T R VG Y D F AV G NA T VK PY LN L AALN EF S D GNK V RLGD ---------- ESVN A SIDGAAFRV G 726
Cdd:pfam03797 158 aaa LS V D S Q SY D S LT G RL G L R LS Y T F DL G GG T LT PY AR L GWRH EF G D DDP V TTAA faglsgagsf TVAG A DLARDSLEL G 237
250
....*....|....*...
gi 446720757 727 AG VQ A DITK N MGA YA SL D 744
Cdd:pfam03797 238 AG LS A QLSD N LSL YA NY D 255
Autotransporter
smart00869 Autotransporter beta-domain; Secretion of protein products occurs by a number of different ...
508-753
7.53e-30
Autotransporter beta-domain; Secretion of protein products occurs by a number of different pathways in bacteria. One of these pathways known as the type IV pathway was first described for the IgA1 protease. The protein component that mediates secretion through the outer membrane is contained within the secreted protein itself, hence the proteins secreted in this way are called autotransporters. This family corresponds to the presumed integral membrane beta-barrel domain that transports the protein. This domain is found at the C-terminus of the proteins it occurs in. The N-terminus contains the variable passenger domain that is translocated across the membrane. Once the passenger domain is exported it is cleaved auto-catalytically in some proteins, in others a different peptidase is used and in some cases no cleavage occurs.
Pssm-ID: 214872 [Multi-domain]
Cd Length: 268
Bit Score: 119.21
E-value: 7.53e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 508 IQYF GG KQKH --- TTA G N A SY D L D VN G VM LG G D T R F m TED G SWLA G V A MSSAKGDMTT ---- MQS KGD TEG Y SFHA Y LSR 580
Cdd:smart00869 1 GRGL GG FLRQ dss GSG G S A GF D Y D SY G LQ LG A D Y R L - SDN G NLSL G F A AGYGNSKVDF sgnk GSG KGD VDS Y GLGL Y AGY 79
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 581 QYN NG IFI D TAAQF G HYS N TADVRLMN GG - G TI K ADFNTN G F GA MVKG GY TWKD G N GL FIQ P Y A K L SALTLEGVDYQLN G 659
Cdd:smart00869 80 SLG NG LYL D AQLGY G RSD N DTKRKVTL GG a G RA K GSYDGT G Y GA SLEA GY RFYL G G GL TLT P F A G L AYSRVRQDGFTES G 159
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 660 VD ----- V H S D S YN S VLGEA G T R VG Y DF A V G NAT - VK PYL N LA ALNE F S D G N K V RLG -------- DESVNASI D GA A FRV 725
Cdd:smart00869 160 GG afgls V D S Q S LD S LSLPL G L R LE Y RL A L G DGA t LT PYL R LA YVHD F Y D D N P V VTA sllgsgas FTTSGTDL D RN A AEL 239
250 260
....*....|....*....|....*...
gi 446720757 726 G A G VQ A DITKNMGAYASL D YTK G DDIEN 753
Cdd:smart00869 240 G L G LS A KLSNGLSLSLNY D GEF G GSSRS 267
COG4625
COG4625 Uncharacterized conserved protein, contains a C-terminal beta-barrel porin domain [Function ...
10-753
2.78e-14
Uncharacterized conserved protein, contains a C-terminal beta-barrel porin domain [Function unknown];
Pssm-ID: 443664 [Multi-domain]
Cd Length: 900
Bit Score: 76.74
E-value: 2.78e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 10 S A LATAIVM A LSAPAFATDSTVSTDPVTLNTEKTTLDQDVVIN G DNKITAVTIETSDSDKDLNVTF GG HDITAASTVNQD 89
Cdd:COG4625 128 G A GGGGGGG A GGGGGGGGGGGAGGGGGGGAGGAGGGGGGGGGG G GGGGGGGGGGGGGGGGGGGGGN GG GGGGGGGGGGGG 207
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 90 FVE G VKVS G NKNVVINATDSTITAQ G E G TYVRTAMVIDSTGDVVVN GG NFVAKNEKGSAT G ISLEATT G NNLTLN G TTIN 169
Cdd:COG4625 208 GGG G GGAG G GGGGGGGGGGGGGGGG G G G GGGGGGGGGGGGAGGGGG GG GGNGGGGGAGGG G GGGGGGS G GGGGGG G GGGS 287
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 170 AQ G NKSYSN G STAIFAQK G NLLQ G FD G DATDNITLADSNIIN GG IETIVTA G NKTGIHTVNLNIKD G SVI G AANNKQTIY 249
Cdd:COG4625 288 GG G GGGGGG G GGGGGGGG G GGGG G GG G GGGGGGGGGGGGGGG GG GGAGGGG G SGGAGAGGGGAGGG G AGG G GGGGTGGGG 367
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 250 ASASAQ G A GS ATQNLNLSVADSTIYSDVLALSESENS A ST T TNVNMNVARSYWE G NAYTFNS G DKA G SDLDINLSDSSVW 329
Cdd:COG4625 368 GGGGGG G G GS GGGGAGGGGGSGGGGGGGAGGGGGGGG A GG T GGGGAGGGGGAAG G GGGGTGA G GGG G GGGTGAGGGGATG 447
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 330 K G KVS G A G DASVSLQN G SVWNVTGSSTVDA L AVKDSTVNI T KATVNTGTFA S QNG TL I V DASSE N TLDISGKASGD L --- 406
Cdd:COG4625 448 G G GGG G G G AGGSGGGA G AGGGSGSGAGTLT L TGNNTYTGT T TVNGGGNYTQ S AGS TL A V EVDAA N SDRLVVTGTAT L ngg 527
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 407 R V YSAGSLDLINEQTAFISTGKDSTLK A TGTTEGG LY QYDLTQG A DGNFYFVKNTHKASN AS SVIQAMA A AP A NVAN L QA 486
Cdd:COG4625 528 T V VVLAGGYAPGTTYTILAVAAALDAL A GNGDLSA LY NALAALD A AAARAALDQLSGEIH AS AAAALLQ A SR A LRDA L SN 607
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 487 DTLSA R QDAVRLSENDK G - GVW I Q Y FG GKQKHTTA G N - A S YD LDVN G VML G G D T R F m TEDGSWLAGVAM S SAKG D MTTMQ 564
Cdd:COG4625 608 RLRAL R GAGAAGDAAAE G w GVW A Q G FG SWGDQDGD G G a A G YD SSTG G LLV G A D Y R L - GDNWRLGVALGY S RSDV D VDDRG 686
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 565 S K GD TEG Y SFHA Y LSR Q YNN g IFI D TAAQF G HYSNTA D -- VRLMNGGG T IK AD FNTNGFG A MVKG GY TWKD G N g L FIQ P Y 642
Cdd:COG4625 687 S S GD SDS Y HLGL Y GGY Q FGA - LYL D GGLGY G WNDYDT D rt IAFGGLSR T AT AD YDGDTAS A FLEA GY RFDL G G - L TLT P F 764
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 643 A K L SALT L EGVDYQLN G ---- VD V H S D S YN S VLGEA G T R VGYD F AV - G NA T VK P YLN L AALN EF S D GNKVR ---- L G DES 713
Cdd:COG4625 765 A G L AYVR L RTDGFTET G gaaa LS V D S Q S TD S LRSTL G L R ASRT F SL g G GV T LT P SGR L GWRH EF G D DDPST tasf A G APG 844
730 740 750 760
....*....|....*....|....*....|....*....|....*
gi 446720757 714 VNASID GA ----- A FRV GAG VQ A DITKNMGAYASL D YTK G DDIEN 753
Cdd:COG4625 845 AAFTVA GA plard A LVL GAG LS A RLSDGLSLGLGY D GEF G SGYTD 889
PL1_Passenger_AT
cd01343 Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 1, of ...
251-461
1.69e-07
Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 1, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of Neisseria and Haemophilus IgA1 proteases, SPATEs (serine protease autotransporters secreted by Enterobacteriaceae), Bordetella pertacins, and nonprotease autotransporters, TibA and similar AIDA-like proteins.
Pssm-ID: 238653 [Multi-domain]
Cd Length: 233
Bit Score: 52.74
E-value: 1.69e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 251 SA S AQ G AGS A TQ N LN L SVADSTI Y SDVLA L SE se NSASTTT N V N MNV A R SY WEGNAYTFNSGDKA G SDLDIN ------ L S 324
Cdd:cd01343 3 LV S DG G NIT A GD N AQ L TLGGGAL Y GSSVT L TN -- GAVLDAG N A N LSA A A SY ATLSGSNIRGTVVL G AGQPLQ alaell L G 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 325 DSSV W K G KVS G A g D A S VSL QNG SVW NV TG S S T V DA L AVKDS TV --- NITKATV NT G T FASQN G T ---- LIV D ASSENT -- 395
Cdd:cd01343 81 GNAA W T G AIQ G L - N A T VSL NLN SVW TL TG D S N V NN L TLNGG TV dfn GPSAGKF NT L T VNTLS G N gtfv MRT D LAGGQG dk 159
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446720757 396 L DIS G K A S GD -- L R V YSA G SLDLINEQTAFI ST G K DSTL --- K A T GT TEG G L Y Q Y D L TQGAD GN FYFVKNT 461
Cdd:cd01343 160 L VVT G S A T GD fn L L V VNT G KEPTSGLNLTLV ST P K GGDA eft L A N GT VDL G A Y R Y T L VKDGN GN WTLTGPK 230
FhaB
COG3210 Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, ...
55-764
3.43e-07
Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 442443 [Multi-domain]
Cd Length: 1698
Bit Score: 54.00
E-value: 3.43e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 55 NK ITA VTIE T SDSDKDL NVT FG G HD IT AASTVNQDFVE G VKV SG NKNVVINA T DSTI T AQ G EGTYVRTAMVID S TGDVVV 134
Cdd:COG3210 796 ID ITA DGTI T AAGTTAI NVT GS G GT IT INTATTGLTGT G DTT SG AGGSNTTD T TTGT T SD G ASGGGTAGANSG S LAATAA 875
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 135 NGGNFVAKNEKGSA T GISLEA T TGNNL T LNGTTIN A QGNKSYSN G STAIFAQK GN LLQ G FD G DATDNIT L ADSNIIN G GI 214
Cdd:COG3210 876 SITVGSGGVATSTG T ANAGTL T NLGTT T NAASGNG A VLATVTAT G TGGGGLTG GN AAA G GT G AGNGTTA L SGTQGNA G LS 955
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 215 ETIVTA G NKTGIHTVNLNIKDGSVIGAANNKQTIYAS A SAQGAGSATQNLNLSVAD S TIYSDVLALSESENSASTT T NVN 294
Cdd:COG3210 956 AASASD G AGDTGASSAAGSSAVGTSANSAGSTGGVIA A TGILVAGNSGTTASTTGG S GAIVAGGNGVTGTTGTASA T GTG 1035
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 295 MNVARSYWE G NAYTFNSGDKAGSDLDINLSDSSV wk GKVSG A GDASVSLQNG S VWNV T GSSTVDALAVKDS T VNI T KATV 374
Cdd:COG3210 1036 TAATAGGQN G VGVNASGISGGNAAALTASGTAGT -- TGGTA A SNGGGGTAQA S GAGT T HTLGGITNGGATG T SGG T TTST 1113
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 375 NTG T FASQN GT LI V D A SSEN T LDISGKAS G D L RVYS A G S LDLINEQT A FISTGKDSTLKA T G TT EGGLYQYDLTQGAD G N 454
Cdd:COG3210 1114 GGV T ASKVG GT TT V G A TGTS T ASTEAAGA G T L TGLV A V S AVAGGASS A SAGDTTAVAAAT T T TT GSAINGGADSAATE G T 1193
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 455 FYFVKNTHKASNA S SVIQAMAAAPANVANLQA DT LSARQDAVRLSENDKGG V WIQYFG G KQKH TT AGN A SYDLDVNGVML 534
Cdd:COG3210 1194 AGTDLKGGDSTGG S TTTIGTTNVTTTTTLTAS DT GNTTATGGSSAGQTGSF V AAGSAS G TGDA TT GAT A GAVSNGATSTV 1273
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 535 G G DTRFMTEDGSWLA G VAMSSAK G DMTT mqskgd T E G YSFH A YLSRQYNNGIFIDTAAQFGHYS N TAD V RLMN G GGTIK A 614
Cdd:COG3210 1274 A G NAGATATGSTVDI G STSATSA G GSLD ------ T T G NTAG A NGATVGTGIGGTTATGTAVAAV N SGG V NAGG G TINTT A 1347
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 615 DFNTNGF G AMVKGGYTWKDGN G LFIQPY A KLS A L T LEGVDYQLN G VDVHSDSYNSVLGEA GT R VG YDFA V GNA TV KPYLN 694
Cdd:COG3210 1348 ANTGLNG G NGATDSAAGAGSG G AAGSLA A TAG A G T VLTGAGNNT G AEGTNAGRDGGVTTS GT G VG NNGG V SGT TV AGTTG 1427
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 695 LA A LNEFSDGNKVRLGDESVNASIDGA A FRVGA G VQADITKNMGAYASLDYTKGDDIENPLQGVV G INVT 764
Cdd:COG3210 1428 SS A TTGTGGTGNTTGTSVAGAGGGNAD A SAINT G NASSLGAGGSTAGNAVGGAVIGGTTTGGNGA G VAGA 1497
PRK14849
PRK14849 autotransporter barrel domain-containing lipoprotein;
82-765
5.03e-05
autotransporter barrel domain-containing lipoprotein;
Pssm-ID: 184851 [Multi-domain]
Cd Length: 1806
Bit Score: 47.04
E-value: 5.03e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 82 A A S TVN QDFVEGVKVS G NK N vv I N A T DS T ITAQ G EGTYVRTAMV I DSTGD V VVNGGNFVAKNEKGSATGIS L EAT TG --- 158
Cdd:PRK14849 1099 G A L TVN KGGISQGELT G GG N -- L N V T GG T LAIE G LNARYNALTS I SPNAE V SLDNTQGLGRGNIANDGLLT L KNV TG elr 1176
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 159 N NLTLN G TTINAQGNKSYSN G STAI F AQKG N LLQ G FDGDATDNIT L A D SNI IN G G IE TI V T AGNKTGI H TVN lnikdgsv 238
Cdd:PRK14849 1177 N SISGK G IVSATARTDVELD G DNSR F VGQF N IDT G SALSVNEQKN L G D ASV IN N G LL TI S T ERSWAMT H SIS -------- 1248
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 239 igaannkqtiy A S ASAQGA G SATQN LN lsv A DS TI Y SDVLALSES E NSASTTTNV NM nvarsywegnaytfnsgdkag SD 318
Cdd:PRK14849 1249 ----------- G S GDVTKL G TGILT LN --- N DS AA Y QGTTDIVGG E IAFGSDSAI NM --------------------- AS 1293
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 319 LD IN LSD S S V WK G K V SG AGD AS V --------------- S L Q NG SV -- W N VT G SSTVDA L A V KDST vnitka T V N T G t FAS 381
Cdd:PRK14849 1294 QH IN IHN S G V MS G N V TT AGD VN V mpggtlrvakttigg N L E NG GT vq M N SE G GKPGNV L T V NGNY ------ T G N N G - LMT 1366
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 382 Q N G TL IV D A S SENTLDIS G KAS G DL RV y SAGSLDLINE QT A ---- F I ST G KD S TLK --- A TGT T E G G L Y Q Y D L TQ G A --- 451
Cdd:PRK14849 1367 F N A TL GG D N S PTDKMNVK G DTQ G NT RV - RVDNIGGVGA QT V ngie L I EV G GN S AGN fal T TGT V E A G A Y V Y T L AK G K gnd 1445
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 452 DG N F Y FVKNTHKAS ------------------------ N A S S V I QAM AAA PANVANLQA D T L SAR Q DAVR L - S ENDKGGV 506
Cdd:PRK14849 1446 EK N W Y LTSKWDGVT ppdtpdpinnppvvdpegpsvyrp E A G S Y I SNI AAA NSLFSHRLH D R L GEP Q YIDS L h S QGSASSM 1525
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 507 W IQYF GG KQK h TT AG NASYDLDV N G -- VM LGGD TRFMTEDGS -- W LA GV AM ------ S SAKGDMTTMQ S K G DTE GYS FHA 576
Cdd:PRK14849 1526 W MRHV GG HER - SR AG DGQLNTQA N R yv LQ LGGD LAQWSSNAQ dr W HL GV MA gyanqh S NTQSNRVGYK S D G RIS GYS AGL 1604
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 577 Y LSRQY N N ---- G IFI D TA A QFGHYS N T advrl MNGGGTIKA D FNTN G FG A M V K GGYT WKD G --------- N GLFI QP Y A 643
Cdd:PRK14849 1605 Y ATWYQ N D ankt G AYV D SW A LYNWFD N S ----- VSSDNRSAD D YDSR G VT A S V E GGYT FEA G tfsgsegtl N TWYV QP Q A 1679
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 644 KLSALTLEGV D Y - QLN G VDVHSDSYNS V LGEA G TRVGYDFAV ----- GNATVK PY LNLAAL N E f S DGNK V RLGDES V NAS 717
Cdd:PRK14849 1680 QITWMGVKDS D H t RKD G TRIETEGDGN V QTRL G VKTYLNSHH qrddg KQREFQ PY IEANWI N N - S KVYA V KMNGQT V GRE 1758
730 740 750 760
....*....|....*....|....*....|....*....|....*...
gi 446720757 718 IDGAAFR V GA GV Q A DITK N MGAYASLDYTK GD DIENPL QG VV G INVT W 765
Cdd:PRK14849 1759 GARNLGE V RT GV E A KVNN N LSLWGNVGVQL GD KGYSDT QG ML G VKYS W 1806
COG4625
COG4625 Uncharacterized conserved protein, contains a C-terminal beta-barrel porin domain [Function ...
13-550
1.44e-04
Uncharacterized conserved protein, contains a C-terminal beta-barrel porin domain [Function unknown];
Pssm-ID: 443664 [Multi-domain]
Cd Length: 900
Bit Score: 45.54
E-value: 1.44e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 13 ATAIVMALSAPAFATDSTVSTDPVTLNTEKTTLDQDVVIN G DNKITAVTIETSDSDKDLNVTF GG HDITAASTVNQDFVE 92
Cdd:COG4625 2 GGGGGGGGGGGGGGGTGGGGAGGGGGAGGGAGGGGAGGGG G GGGGGGGAGGGGGGGGTGGGGG GG GGGGGGGAGGGGGGG 81
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 93 G VKVS G NKNVVINATDSTITAQ G E G TYVRTAMVIDSTGDVVVN G GNFVAKNEK G S A T G ISLEATT G NNLTLN G TTINAQ G 172
Cdd:COG4625 82 G GGGG G GGTGGVGGGGGGGGGG G G G GGGGGGGGGGGSAGGGGG G AGGAGGGGG G G A G G GGGGGGG G GAGGGG G GGAGGA G 161
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 173 NKSYSN G STAIFAQK G NLLQ G FD G DATDNITLADSNIIN GG IETIVTA G NKTGIHTVNLNIKD G SVI G AANNKQTIYASA 252
Cdd:COG4625 162 GGGGGG G GGGGGGGG G GGGG G GG G GGGGGGGNGGGGGGG GG GGGGGGG G GGGAGGGGGGGGGG G GGG G GGGGGGGGGGGG 241
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 253 SAQ G A G SATQNLNLSVADSTIYSDVLALSESEN S ASTTTNVNMNVARSYWE G NAYTFNS G DKA G SDLDINLSDSSVWK G K 332
Cdd:COG4625 242 GGG G G G AGGGGGGGGGNGGGGGAGGGGGGGGGG S GGGGGGGGGGGSGGGGG G GGGGGGG G GGG G GGGGGGGGGGGGGG G G 321
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 333 VS G A G DASVSLQN G SVWNVT G SSTVDAL A VKDSTVNITKATVNT G TFASQN G TLIVDASSENTLDI SG KAS G DLRVYSA G 412
Cdd:COG4625 322 GG G G G GGGGGGGA G GGGGSG G AGAGGGG A GGGGAGGGGGGGTGG G GGGGGG G GGGSGGGGAGGGGG SG GGG G GGAGGGG G 401
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 413 SLDLINEQTAFIST G KDSTLKAT G T T EG G LYQYDLTQ GA D G NFYFVKNTHKASN A SSVIQAMA A APANVANLQAD TL SAR 492
Cdd:COG4625 402 GGGAGGTGGGGAGG G GGAAGGGG G G T GA G GGGGGGGT GA G G GGATGGGGGGGGG A GGSGGGAG A GGGSGSGAGTL TL TGN 481
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....*...
gi 446720757 493 QDAVRLSENDK GG VWI Q YF G GKQKHTTAGNA S YD L D V N G VMLGGDTRFMTED G SWLA G 550
Cdd:COG4625 482 NTYTGTTTVNG GG NYT Q SA G STLAVEVDAAN S DR L V V T G TATLNGGTVVVLA G GYAP G 539
FhaB
COG3210 Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, ...
9-416
4.41e-04
Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 442443 [Multi-domain]
Cd Length: 1698
Bit Score: 43.99
E-value: 4.41e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 9 RSALATAIVM A LSAPAFATDSTVSTDPV T L N TEKTTLDQDVVI N GDNKI T AVTIETSDSDKDLNV T FG G HDIT A ASTVNQ 88
Cdd:COG3210 308 GTGVLGGGTA A GITTTNTVGGNGDGNNT T A N SGAGLVSGGTGG N NGTTG T GAGSGLTGTGNGGGL T TA G AGTV A STVGTA 387
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 89 DFVE G VKV S GNKNVVINATDSTITAQGE G TYVRTAMVIDS T GDV V VNGGNFVAKNEKGSATGISLEA T T G NN L TL N GTTI 168
Cdd:COG3210 388 TAST G NAS S TTVLGSGSLATGNTGTTIA G NGGSANAGGFT T TGG V LGITGNGTVTGGTIGGLTGSGT T N G AG L SG N TDVS 467
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 169 NAQGNKSYSNG - ST A IFAQK G NLLQGFDGDATD N ITLA D S N I I NG G IET I VTA G NKT G IH T VNLNIK DG SVIGAANNKQ T 247
Cdd:COG3210 468 GTGTVTNSAGN t TS A TTLAG G GIGTVTTNATIS N NAGG D A N G I AT G LTG I TAG G GGG G NA T SGGTGG DG TTLSGSGLTT T 547
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 248 IYAS AS AQG A G S ATQNL N LSVADSTIYSDVL A LS e SE NS A S T T TNVNM N VARSYWEGNAYTFNSGDKAGSDLDINLSDSS 327
Cdd:COG3210 548 VSGG AS GTT A A S GSNTA N TLGVLAATGGTSN A TT - AG NS T S A T GGTGT N SGGTVLSIGTGSAGATGTITLGAGTSGAGAN 626
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 328 VWK G KVSGA G D A SVSLQN G SVWNV TG SSTVDALAVKDSTVNITKATVN TGT FA S QNGTLIVDASSENTLDISGKAS G DLR 407
Cdd:COG3210 627 ATG G GAGLT G S A VGAALS G TGSGT TG TASANGSNTTGVNTAGGTGGGT TGT VT S GATGGTTGTTLNAATGGTLNNA G NTL 706
....*....
gi 446720757 408 VY S A GS LDL 416
Cdd:COG3210 707 TI S T GS ITV 715
PRK09752
PRK09752 AIDA-I family autotransporter YfaL;
508-765
4.59e-04
AIDA-I family autotransporter YfaL;
Pssm-ID: 182059 [Multi-domain]
Cd Length: 1250
Bit Score: 43.89
E-value: 4.59e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 508 IQYF GG KQKH T T AG NASYDL D VNG V M L G GD T --- R FMT e DG S W LA G V ---------- AM S SAK G DMTTM Q SK G DTE G YSF 574
Cdd:PRK09752 989 LRVI GG DYHY T A AG QLAQHE D TST V Q L S GD L fsg R WGD - DG E W ML G I vggysdnqgd SR S NMT G TRADN Q NH G YAV G LTS 1067
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 575 HAYLSRQYNN G IFI D TAA Q FGHYS N ta DV RLMNG G gti KADFNTN G FG A MVKG GY T W KD G N G LF I Q P Y A KLSALTLEGV D 654
Cdd:PRK09752 1068 SWFQHGNQKQ G AWL D SWL Q YAWFN N -- DV SEQED G --- TDHYHSS G II A SLEA GY Q W LP G R G VV I E P Q A QVIYQGVQQD D 1142
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 655 YQ - L N GVD V HSDSYNSVLGEA G TRVGYDF AV G nat V K P Y L N laa LN EFS D GNKVRLGDESVNA S I D GAAF R -- VGA GV QA 731
Cdd:PRK09752 1143 FT a A N HAR V SQSQGDDIQTRL G LHSEWRT AV H --- V I P T L D --- LN YYH D PHSTEIEEDGSTI S D D AVKQ R ge IKV GV TG 1216
250 260 270
....*....|....*....|....*....|....
gi 446720757 732 D I TKNMGAYA S LDYT KG D D IENPLQ G VVGIN V T W 765
Cdd:PRK09752 1217 N I SQRVSLRG S VAWQ KG S D DFAQTA G FLSMT V K W 1250
34
PHA02584 long tail fiber, proximal subunit; Provisional
46-277
7.60e-04
long tail fiber, proximal subunit; Provisional
Pssm-ID: 222890 [Multi-domain]
Cd Length: 1229
Bit Score: 43.21
E-value: 7.60e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 46 D Q D VVI NG DNKI T AV T IETSDSDKDLNV TFGG HDITAASTVN Q DFVE G VK V SGNKNV ---- VI N A T DST I TAQGE GT YVR 121
Cdd:PHA02584 902 D I D QTV NG SLTF T KN T NLSAPLVSSSTA TFGG SVTANSTLTT Q NTSN G TV V VVDETS iafy SQ N N T TGN I VFNID GT VDP 981
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 122 TAMV id ST G D ----- V VV NG GNFV A KNEKGSA T GISLE A T TG NNLTL N GTTINAQGNKSYSNGSTAIFAQ K GNLLQ gfdg 196
Cdd:PHA02584 982 INVN -- AN G T lnatg V AT NG RAVY A EGGGIAR T NNAAR A I TG GFTIR N DGSTTVFLLTAAGDQTGGFNGL K SLIIN ---- 1055
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 197 D A TDNI T LA D SN IIN G G IETI vtagnk T G IH TVN LN I K dgsvigaann K Q TIY AS ASAQGAGSATQNLNLSVA DS TI Y SD 276
Cdd:PHA02584 1056 N A NGQV T IN D NY IIN A G GTIM ------ S G GL TVN SR I R ---------- S Q GTK AS YTRAPTADTVGFWSVDIN DS AT Y NQ 1119
.
gi 446720757 277 V 277
Cdd:PHA02584 1120 F 1120
PRK15319
PRK15319 fibronectin-binding autotransporter adhesin ShdA;
93-402
1.12e-03
fibronectin-binding autotransporter adhesin ShdA;
Pssm-ID: 185219 [Multi-domain]
Cd Length: 2039
Bit Score: 42.76
E-value: 1.12e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 93 GVKV S GNKNVVINA TD ST IT AQ G --- E G TYVRTAMVIDS T GDVVVNG GNF ---- VAKNEKGSAT G ISL EA TTGNNLTLN - 164
Cdd:PRK15319 135 SNAI S LDHYAILEL TD AK IT TT G iyt Q G ISAADGSTLTL T DSTLTID GNF gvmt LYTGSEATLD G TIV EA ANSSSAQVQ q 214
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 165 G T T I N AQGNKSYSNGSTA I FAQK GN LLQ gfdg D ATDNIT L A DS NIING G IETIVTAG NK TGIHTV N LN I KDGSVI GAA -- 242
Cdd:PRK15319 215 G S T L N VLDGSTITLAQGQ I NVVA GN TAT ---- D EGSTLN L S DS SVSSA G TMSTIQGT NK AALNLT N AT I THTNAS GAA vq 290
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 243 - NN KQ T -------------- I Y AS AS AQGAGS AT Q N LN -------------------- L S V A D STIY SD VL AL ---- S ES 283
Cdd:PRK15319 291 a NN AT T ldisggnitsagtg V Y IL AS DARIDG AT I N AD gdgifitskrkltgyedlna L T V S D ANVT SD TV AL hvdg S TT 370
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 284 E N SASTT T NVNMNVARSYWE G NAY T FNS ------ G DKAGS D LD --- IN LS DS S VWK G K V SGA g DASV SL QNG S V WN V T GS 354
Cdd:PRK15319 371 I N DPIEL T DSTFTAPTAIKL G SKA T IQA enttlt G NIVQT D AS sss LS LS QG S TLT G S V DAM - FTTL SL DDT S Q WN M T DP 449
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|
gi 446720757 355 STV DA L A v K D STVNITK A TVN TGT FASQNG TL IVDAS S E -- N TLD ISGKA 402
Cdd:PRK15319 450 STV GN L T - N D GDITLGN A SGS TGT LLTVDN TL TLQDG S Q in A TLD TANSS 498
Hia
COG5295 Autotransporter adhesin [Intracellular trafficking, secretion, and vesicular transport, ...
10-454
2.55e-03
Autotransporter adhesin [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];
Pssm-ID: 444098 [Multi-domain]
Cd Length: 785
Bit Score: 41.29
E-value: 2.55e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 10 S A LATAIVM A LSAPAFATDSTVSTDPV T LNTEK T TLDQDVVIN G DNKIT A VTIE T SD S DKDLNVTFGGHDIT A AS T VNQD 89
Cdd:COG5295 142 A A STGGSSA A GGSNTATATGSSTANAA T AAAGA T STSASGSSS G ASGAA A ASAA T GA S AGGTASAAASASSS A TG T SASV 221
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 90 F V EGVKVS G NKNVVINATDSTITAQGEG T YVRTAMVIDSTGDVVVNGGNFVAKNEKGS A T G ISLE A TT G NNLTLNGTTIN 169
Cdd:COG5295 222 G V NAGAAT G SAASAGGSASAGAASGNAT T ASASSVSGSAVAAGTASTATTASTTAASG A A G TATA A AG G DAAAAGSASST 301
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 170 AQG N KSYSN G STAIFAQKGNL L QGFD G DATDNITLAD S NIINGGIE T IVT AG NKTGIHT ---- VNLNIKDGSVIGAANNK 245
Cdd:COG5295 302 GAA N ATAGG G NAGSGGGGAAA L GSAG G SSGVGTASGA S AAAATNDG T ANG AG TSAAADA tsgg GAGGGGAAATSSSGGSA 381
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 246 QTIYAS A S A Q GAGSA TQNLNLSV A DSTIYSDVLALSESENS A ST T TNVNMN V AR S YWEGNAYTFN S GDK A GSDLDINLSD 325
Cdd:COG5295 382 TAAGNA A G A A GAGSA GSGGSSTG A SAGGGASAAGGAAAGSA A AG T SSNTSA V GA S NGASGTSSSA S SAG A AGGGTAGAGG 461
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 326 SSVWKGKVSG A GD A SVSLQNG S VWNVT G SSTVD A L A VKDSTVNITKATVNTGTFASQNGTLIVDASSENTLDIS G K A SGD 405
Cdd:COG5295 462 AANVGAATTA A SA A ATAAAAT S SAAIA G ATATG A G A AAGGAGAGAAGGAGSAAAGGAANAAAASGATATAGSAG G G A AAA 541
410 420 430 440
....*....|....*....|....*....|....*....|....*....
gi 446720757 406 LRVY S AGSLDLI N EQTAFIS T GKDSTLK A T G TTEGGLYQYDLTQ GA D G N 454
Cdd:COG5295 542 AGGG S TTAATGT N SVAVGNN T ATGANSV A L G AGSVASGANSVSV GA A G A 590
PL2_Passenger_AT
cd01344 Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 2, of ...
304-408
5.82e-03
Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 2, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of the nonprotease autotransporters, Ag43, AIDA-1 and IcsA, as well as, the less characterized ShdA, MisL, and BapA autotransporters.
Pssm-ID: 238654 [Multi-domain]
Cd Length: 188
Bit Score: 38.82
E-value: 5.82e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446720757 304 GN AYTFNS GD KAGSDLDIN L SD S SVWK G KVSGA G DASVS L QNG S V WN V TG S ST VDALAVKDSTVNI ------- TKATVN T 376
Cdd:cd01344 5 GN GGWKLG GD LTLGGGALT L TT S LTLT G TLLTG G AGTLT L DST S T WN I TG T ST LNVGNLTNAGTID lgngspa GGTLTI T 84
90 100 110
....*....|....*....|....*....|....*...
gi 446720757 377 G TFASQN GTL IV ------ D A S SENT L D I S G K ASG DL RV 408
Cdd:cd01344 85 G NYTGNG GTL RL ntvlgd D D S PTDR L V I D G D ASG TT RV 122
Blast search parameters
Data Source:
Precalculated data, version = cdd.v.3.21
Preset Options: Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
