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Conserved domains on  [gi|446716474|ref|WP_000793792|]
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CRP-S regulon transcriptional coactivator Sxy [Escherichia coli]

Protein Classification

TfoX/Sxy family DNA transformation protein( domain architecture ID 10006898)

TfoX/Sxy family DNA transformation protein similar to the N-terminal domains of Escherichia coli competence activator Sxy and Haemophilus influenzae DNA transformation protein TfoX

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TfoX COG3070
Transcriptional regulator of competence genes, TfoX/Sxy family [Transcription];
1-113 5.24e-37

Transcriptional regulator of competence genes, TfoX/Sxy family [Transcription];


:

Pssm-ID: 442304  Cd Length: 114  Bit Score: 125.01  E-value: 5.24e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446716474   1 MKnLSYKRIYKSQEYLATLGTIEYRSLFGSYSLTVDDTVFAMVSDGELYLRACEQSAQYCVKHPPVWLTYKKCGRSVTLN 80
Cdd:COG3070    1 MA-SSEELVERVRELLAPLGPVTARRMFGGYGLYVDGKMFALVSDDELYLKADEELREAFEAAGCEPFTYEKRGRPVTLG 79

                         90       100       110
                 ....*....|....*....|....*....|...
gi 446716474  81 YYRVDESLWRNQLKLVRLSKYSLDAALKEKSTR 113
Cdd:COG3070   80 YYLVPEELLDDPDELLEWARLALEAALRAKPKK 112
TfoX_C pfam04994
TfoX C-terminal domain; TfoX may play a key role in the development of genetic competence by ...
 118-194 1.57e-32

TfoX C-terminal domain; TfoX may play a key role in the development of genetic competence by regulating the expression of late competence-specific genes. This family corresponds to the C-terminal presumed domain of TfoX. The domain is found associated with pfam00383 in Swiss:Q9JZR1. It is also found as an isolated domain in some proteins suggesting this is an autonomous domain.


:

Pssm-ID: 461512 [Multi-domain]  Cd Length: 77  Bit Score: 112.27  E-value: 1.57e-32
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446716474  118 RLKDLPNMSFHLEAILGEVGIKDVRALRILGAKMCWLRLRQQNSLVTEKILFMLEGAIIGIHEAALPVARRQELAEW 194
Cdd:pfam04994   1 RLKDLPNLGLKLERMLKKAGIKTVADLRELGAVEAYLRLKQSGSSVSLNLLWALEGALQGVHWNVLPEERKEELLAQ 77
 
Name Accession Description Interval E-value
TfoX COG3070
Transcriptional regulator of competence genes, TfoX/Sxy family [Transcription];
1-113 5.24e-37

Transcriptional regulator of competence genes, TfoX/Sxy family [Transcription];


Pssm-ID: 442304  Cd Length: 114  Bit Score: 125.01  E-value: 5.24e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446716474   1 MKnLSYKRIYKSQEYLATLGTIEYRSLFGSYSLTVDDTVFAMVSDGELYLRACEQSAQYCVKHPPVWLTYKKCGRSVTLN 80
Cdd:COG3070    1 MA-SSEELVERVRELLAPLGPVTARRMFGGYGLYVDGKMFALVSDDELYLKADEELREAFEAAGCEPFTYEKRGRPVTLG 79

                         90       100       110
                 ....*....|....*....|....*....|...
gi 446716474  81 YYRVDESLWRNQLKLVRLSKYSLDAALKEKSTR 113
Cdd:COG3070   80 YYLVPEELLDDPDELLEWARLALEAALRAKPKK 112
TfoX_C pfam04994
TfoX C-terminal domain; TfoX may play a key role in the development of genetic competence by ...
 118-194 1.57e-32

TfoX C-terminal domain; TfoX may play a key role in the development of genetic competence by regulating the expression of late competence-specific genes. This family corresponds to the C-terminal presumed domain of TfoX. The domain is found associated with pfam00383 in Swiss:Q9JZR1. It is also found as an isolated domain in some proteins suggesting this is an autonomous domain.


Pssm-ID: 461512 [Multi-domain]  Cd Length: 77  Bit Score: 112.27  E-value: 1.57e-32
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446716474  118 RLKDLPNMSFHLEAILGEVGIKDVRALRILGAKMCWLRLRQQNSLVTEKILFMLEGAIIGIHEAALPVARRQELAEW 194
Cdd:pfam04994   1 RLKDLPNLGLKLERMLKKAGIKTVADLRELGAVEAYLRLKQSGSSVSLNLLWALEGALQGVHWNVLPEERKEELLAQ 77
TfoX_N pfam04993
TfoX N-terminal domain; TfoX may play a key role in the development of genetic competence by ...
 14-106 4.85e-31

TfoX N-terminal domain; TfoX may play a key role in the development of genetic competence by regulating the expression of late competence-specific genes. This family corresponds to the N-terminal presumed domain of TfoX. The domain is found as an isolated domain in some proteins suggesting this is an autonomous domain.


Pssm-ID: 428245  Cd Length: 91  Bit Score: 108.82  E-value: 4.85e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446716474   14 EYLATLGTIEYRSLFGSYSLTVDDTVFAMVSDGELYLRACEQSAQYCVKHPPVWLTYKKcgRSVTLNYYRVDESLWRNQL 93
Cdd:pfam04993   1 ELLAPLGPVTSRRMFGGYGLYVDGLMFALVSDGELYLRADEETREEFEAAGCEPFVYAK--RGVTLSYYRVPADALEDPE 78

                          90
                  ....*....|...
gi 446716474   94 KLVRLSKYSLDAA 106
Cdd:pfam04993  79 QLARWARLALEAA 91
 
Name Accession Description Interval E-value
TfoX COG3070
Transcriptional regulator of competence genes, TfoX/Sxy family [Transcription];
1-113 5.24e-37

Transcriptional regulator of competence genes, TfoX/Sxy family [Transcription];


Pssm-ID: 442304  Cd Length: 114  Bit Score: 125.01  E-value: 5.24e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446716474   1 MKnLSYKRIYKSQEYLATLGTIEYRSLFGSYSLTVDDTVFAMVSDGELYLRACEQSAQYCVKHPPVWLTYKKCGRSVTLN 80
Cdd:COG3070    1 MA-SSEELVERVRELLAPLGPVTARRMFGGYGLYVDGKMFALVSDDELYLKADEELREAFEAAGCEPFTYEKRGRPVTLG 79

                         90       100       110
                 ....*....|....*....|....*....|...
gi 446716474  81 YYRVDESLWRNQLKLVRLSKYSLDAALKEKSTR 113
Cdd:COG3070   80 YYLVPEELLDDPDELLEWARLALEAALRAKPKK 112
TfoX_C pfam04994
TfoX C-terminal domain; TfoX may play a key role in the development of genetic competence by ...
 118-194 1.57e-32

TfoX C-terminal domain; TfoX may play a key role in the development of genetic competence by regulating the expression of late competence-specific genes. This family corresponds to the C-terminal presumed domain of TfoX. The domain is found associated with pfam00383 in Swiss:Q9JZR1. It is also found as an isolated domain in some proteins suggesting this is an autonomous domain.


Pssm-ID: 461512 [Multi-domain]  Cd Length: 77  Bit Score: 112.27  E-value: 1.57e-32
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446716474  118 RLKDLPNMSFHLEAILGEVGIKDVRALRILGAKMCWLRLRQQNSLVTEKILFMLEGAIIGIHEAALPVARRQELAEW 194
Cdd:pfam04994   1 RLKDLPNLGLKLERMLKKAGIKTVADLRELGAVEAYLRLKQSGSSVSLNLLWALEGALQGVHWNVLPEERKEELLAQ 77
TfoX_N pfam04993
TfoX N-terminal domain; TfoX may play a key role in the development of genetic competence by ...
 14-106 4.85e-31

TfoX N-terminal domain; TfoX may play a key role in the development of genetic competence by regulating the expression of late competence-specific genes. This family corresponds to the N-terminal presumed domain of TfoX. The domain is found as an isolated domain in some proteins suggesting this is an autonomous domain.


Pssm-ID: 428245  Cd Length: 91  Bit Score: 108.82  E-value: 4.85e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446716474   14 EYLATLGTIEYRSLFGSYSLTVDDTVFAMVSDGELYLRACEQSAQYCVKHPPVWLTYKKcgRSVTLNYYRVDESLWRNQL 93
Cdd:pfam04993   1 ELLAPLGPVTSRRMFGGYGLYVDGLMFALVSDGELYLRADEETREEFEAAGCEPFVYAK--RGVTLSYYRVPADALEDPE 78

                          90
                  ....*....|...
gi 446716474   94 KLVRLSKYSLDAA 106
Cdd:pfam04993  79 QLARWARLALEAA 91
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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