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Conserved domains on  [gi|446701131|ref|WP_000778477|]
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MULTISPECIES: superantigen-like protein SSL10 [Staphylococcus]

Protein Classification

PRK13038 family protein( domain architecture ID 11486426)

PRK13038 family protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK13038 PRK13038
superantigen-like protein SSL10; Reviewed;
1-227 4.65e-153

superantigen-like protein SSL10; Reviewed;


:

Pssm-ID: 171853  Cd Length: 227  Bit Score: 424.04  E-value: 4.65e-153
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446701131   1 MKLTAIAKAALALGILTTGTLTTEVHSGHAKQNQKSVNKHDKEALYRYYTGKTMEMKNISALKHGKNNLRFKFRGIKIQV 80
Cdd:PRK13038   1 MKFTALAKATLALGILTTGTLTTEVHSGHAKQNQKSVNKHDKEALYRYYTGKTMEMKNISALKHGKNNLRFKFRGIKIQV 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446701131  81 LLPGNDKSKFQQRSYEGLDVFFVQEKRDKHDIFYTVGGVIQNNKTSGVVSAPILNISKEKGEDAFVKGYPYYIKKEKITL 160
Cdd:PRK13038  81 LLPGNDKSKFQQRSYEGLDVFFVQEKRDKHDIFYTVGGVIQNNKTSGVVSAPILNISKEKGEDAFVKGYPYYIKKEKITL 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446701131 161 KELDYKLRKHLIEKYGLYKTISKDGRVKISLKDGSFYNLDLRSKLKFKYMGEVIESKQIKDIEVNLK 227
Cdd:PRK13038 161 KELDYKLRKHLIEKYGLYKTISKDGRVKISLKDGSFYNLDLRSKLKFKYMGEVIESKQIKDIEVNLK 227
 
Name Accession Description Interval E-value
PRK13038 PRK13038
superantigen-like protein SSL10; Reviewed;
1-227 4.65e-153

superantigen-like protein SSL10; Reviewed;


Pssm-ID: 171853  Cd Length: 227  Bit Score: 424.04  E-value: 4.65e-153
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446701131   1 MKLTAIAKAALALGILTTGTLTTEVHSGHAKQNQKSVNKHDKEALYRYYTGKTMEMKNISALKHGKNNLRFKFRGIKIQV 80
Cdd:PRK13038   1 MKFTALAKATLALGILTTGTLTTEVHSGHAKQNQKSVNKHDKEALYRYYTGKTMEMKNISALKHGKNNLRFKFRGIKIQV 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446701131  81 LLPGNDKSKFQQRSYEGLDVFFVQEKRDKHDIFYTVGGVIQNNKTSGVVSAPILNISKEKGEDAFVKGYPYYIKKEKITL 160
Cdd:PRK13038  81 LLPGNDKSKFQQRSYEGLDVFFVQEKRDKHDIFYTVGGVIQNNKTSGVVSAPILNISKEKGEDAFVKGYPYYIKKEKITL 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446701131 161 KELDYKLRKHLIEKYGLYKTISKDGRVKISLKDGSFYNLDLRSKLKFKYMGEVIESKQIKDIEVNLK 227
Cdd:PRK13038 161 KELDYKLRKHLIEKYGLYKTISKDGRVKISLKDGSFYNLDLRSKLKFKYMGEVIESKQIKDIEVNLK 227
SSL_OB pfam09199
Staphylococcal superantigen-like OB-fold domain; This OB-fold domain folds into a ...
 43-123 2.90e-26

Staphylococcal superantigen-like OB-fold domain; This OB-fold domain folds into a five-stranded beta-barrel. Members of this family are found in various staphylococcal toxins described as staphylococcal superantigen-like (SSL) proteins that are related to the staphylococcal enterotoxins (SEs) or superantigens. These SSL proteins of which 11 have so far been characterized have a typical SE tertiary structure consisting of a distinct oligonucleotide/oligosaccharide binding (OB-fold), this domain, linked to a beta-grasp domain, family Stap_Strp_tox_C, pfam02876. SSLs do not bind to T-cell receptors or major histocompatibility complex class II molecules and do not stimulate T cells. SSLs target components of innate immunity, such as complement, Fc receptors, and myeloid cells 2,3,4,5,6,7,8]. SSL protein 7 (SSL7) is the best characterized of the SSLs and binds complement factor C5 and IgA with high affinity and inhibits the end stage of complement activation and IgA binding to FcalphaR.


Pssm-ID: 401224 [Multi-domain]  Cd Length: 84  Bit Score: 96.99  E-value: 2.90e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446701131   43 EALYRYYTGKTMEMKNISALK---HGKNNLRFKFRGIKIQVLLPGNDKSKFQQRSYEGLDVFFVQEKRDKHDIFYTVGGV 119
Cdd:pfam09199   1 KDLKAYYSKPSFELKNVSGYKekkTGKNFLNFTPNNQKYQVALLGKDKEKYKEGEHDNLDVFVVRELEDRNGRKYSVGGV 80


                  ....
gi 446701131  120 IQNN 123
Cdd:pfam09199  81 TKKN 84
 
Name Accession Description Interval E-value
PRK13038 PRK13038
superantigen-like protein SSL10; Reviewed;
1-227 4.65e-153

superantigen-like protein SSL10; Reviewed;


Pssm-ID: 171853  Cd Length: 227  Bit Score: 424.04  E-value: 4.65e-153
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446701131   1 MKLTAIAKAALALGILTTGTLTTEVHSGHAKQNQKSVNKHDKEALYRYYTGKTMEMKNISALKHGKNNLRFKFRGIKIQV 80
Cdd:PRK13038   1 MKFTALAKATLALGILTTGTLTTEVHSGHAKQNQKSVNKHDKEALYRYYTGKTMEMKNISALKHGKNNLRFKFRGIKIQV 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446701131  81 LLPGNDKSKFQQRSYEGLDVFFVQEKRDKHDIFYTVGGVIQNNKTSGVVSAPILNISKEKGEDAFVKGYPYYIKKEKITL 160
Cdd:PRK13038  81 LLPGNDKSKFQQRSYEGLDVFFVQEKRDKHDIFYTVGGVIQNNKTSGVVSAPILNISKEKGEDAFVKGYPYYIKKEKITL 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446701131 161 KELDYKLRKHLIEKYGLYKTISKDGRVKISLKDGSFYNLDLRSKLKFKYMGEVIESKQIKDIEVNLK 227
Cdd:PRK13038 161 KELDYKLRKHLIEKYGLYKTISKDGRVKISLKDGSFYNLDLRSKLKFKYMGEVIESKQIKDIEVNLK 227
PRK13346 PRK13346
superantigen-like protein SSL7; Reviewed;
1-227 4.11e-45

superantigen-like protein SSL7; Reviewed;


Pssm-ID: 106304 [Multi-domain]  Cd Length: 231  Bit Score: 150.16  E-value: 4.11e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446701131   1 MKLTAIAKAALALGILTTGTLTTEVHSGHAKQNQKSVNK-HDKEALYRYYTGKTMEMKNISAL---KHGKNNLRFKFRGI 76
Cdd:PRK13346   1 MKLKTLAKATLALGLLTTGVITSEGQAVQAKEKQERVQHlYDIKDLHRYYSSESFEFSNISGKvenYNGSNVVRFNQENQ 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446701131  77 KIQVLLPGNDKSKFQQrSYEGLDVFFVQEKRDKHDIFYTVGGVIQNNKTSGVVSAPILnISKEKGEDAFVKGYPYYIKKE 156
Cdd:PRK13346  81 NHQLFLLGKDKDKYKE-GLEGQNVFVVKELIDPNGRLSTVGGVTKKNNKSSETNTHLF-VNKVYGGNLDASIDSFLINKE 158

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446701131 157 KITLKELDYKLRKHLIEKYGLYKTISKDGRVKISLKDGSFYNLDLRSKLKFKYMGEVIESKQIKDIEVNLK 227
Cdd:PRK13346 159 EVSLKELDFKIRQQLVENYGLYKGTTKYGKITINLKDEKKEEIDLGDKLQFERMGDVLNSKDIQNIAVTIN 229
PRK13036 PRK13036
superantigen-like protein SSL11; Reviewed;
1-226 5.39e-42

superantigen-like protein SSL11; Reviewed;


Pssm-ID: 171852  Cd Length: 227  Bit Score: 142.01  E-value: 5.39e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446701131   1 MKLTAIAKAALALGILTTGTLTTEVHSghAKQNQKSVNKHDKEALYRYYTGKTMEMKNISALKHGkNNLRFKFRGIKIQV 80
Cdd:PRK13036   1 MKLKNIAKASLALGILTTGMITTTAQP--VKASTLEVRSQATQDLSEYYKGRGFELTNVSGYKEG-NKVTFIDNSQLIDV 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446701131  81 LLPGNDKSKFQQ-RSYEGLDVFFVQEKRDKHDIFYTVGGVIQNNKTS--GVVSAPILNISKEKGED-AFVKGYPYYIKKE 156
Cdd:PRK13036  78 TLTGNEKLTFKDdEDVSNVDVFVVREGSDKSAITTSIGGITKTNGTQykDTVQNVNLSISKSTGQHtTSVTSEYYSINKE 157

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446701131 157 KITLKELDYKLRKHLIEKYGLYKTISKDGRVKISLKDGSFYNLDLRSKLKFKYMGEVIESKQIKDIEVNL 226
Cdd:PRK13036 158 EISLKELDFKLRKHLIDKHDLYKTEPKDSKIRITMKNGGYYTFELNKKLQPHRMGDTIDSRNIEKIEVNL 227
PRK13345 PRK13345
superantigen-like protein SSL9; Reviewed;
1-226 8.50e-38

superantigen-like protein SSL9; Reviewed;


Pssm-ID: 106303  Cd Length: 232  Bit Score: 131.28  E-value: 8.50e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446701131   1 MKLTAIAKAALALGILTTGTLTTEVHSGHAK-QNQKSVNKHDKEALYRYYTGKTMEMKNISALK---HGKNNLRFKFRGI 76
Cdd:PRK13345   1 MKLTALAKATLALGILTTGVFTAESKAVHAKvELDETQRKYYINMLHQYYSEESFEPTNISVKSedyYGSNVLNFKQRNK 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446701131  77 KIQVLLPGNDKSKFQQRSYeGLDVFFVQEKRDKHDIFYTVGGVIQNNKTS--GVVSAPILNISKEKGEDAFVKGYPYYIK 154
Cdd:PRK13345  81 AFKVFLLGDDKNKYKEKTH-GLDVFAVPELIDIKGGIYSVGGITKKNVRSvfGFVSNPSLQVKKVDAKHGFSINELFFIQ 159

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446701131 155 KEKITLKELDYKLRKHLIEKYGLYKTISKDGRVKISLKDGSFYNLDLRSKLKFKYMGEVIESKQIKDIEVNL 226
Cdd:PRK13345 160 KEEVSLKELDFKIRKMLVEKYRLYKGASDKGRIVINMKDEKKYVIDLSEKLSFDRMFDVMDSKQIKNIEVNL 231
PRK13039 PRK13039
superantigen-like protein SSL8; Reviewed;
1-227 1.40e-36

superantigen-like protein SSL8; Reviewed;


Pssm-ID: 171854  Cd Length: 232  Bit Score: 128.27  E-value: 1.40e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446701131   1 MKLTAIAKAALALGILTTGTLTTEVHSGHAKQNQKSVNK-HDKEALYRYYTGKTMEMKNISALKHG---KNNLRFKFRGI 76
Cdd:PRK13039   1 MKFTAIAKAIFVLGILTTSVMITENQSVNAKGKYEKMNRlYDTNKLHQYYSGPSYELTNVSGQSQGyydSNVLLFNQQNQ 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446701131  77 KIQVLLPGNDKSKFQQRSYeGLDVFFVQEKRDKHDIFYTVGGVIQNNKTSGVVS--APILNISKEKGEDAFVKGYPYYIK 154
Cdd:PRK13039  81 KFQVFLLGKDENKYKEKTH-GLDVFAVPELVDLDGRIFSVSGVTKKNVKSIFESlrTPNLLVKKIDDKDGFSIDEFFFIQ 159

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446701131 155 KEKITLKELDYKLRKHLIEKYGLYKTISKDGRVKISLKDGSFYNLDLRSKLKFKYMGEVIESKQIKDIEVNLK 227
Cdd:PRK13039 160 KEEVSLKELDFKIRKLLIKKYKLYEGSADKGRIVINMKDENKYEIDLSDKLDFERMADVINSEQIKNIEVNLK 232
PRK13037 PRK13037
superantigen-like protein SSL1; Reviewed;
1-227 6.30e-36

superantigen-like protein SSL1; Reviewed;


Pssm-ID: 106074  Cd Length: 226  Bit Score: 126.63  E-value: 6.30e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446701131   1 MKLTAIAKAALALGILTTGTLTTEVHSGHAKQNQKSVNKHDkeaLYRYYTGKTMEMKNISALKH---GKNNLRFKFRGIK 77
Cdd:PRK13037   1 MKFKAIAKASLALGMLATGVITSNVQSVQAKTEVKQQSESE---LKHYYNKPVLERKNVTGYKYtekGKDYIDVIVDNQY 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446701131  78 IQVLLPGNDKSKFQQRSYEGLDVFFVQEKRDKHDIFYTVGGVIQNNKTSGV--VSAPILNISKEKGEdafVKGYPYYIKK 155
Cdd:PRK13037  78 SQISLVGSDKDKFKDGDNSNIDVFILREGDSRQATNYSIGGVTKTNSQPYIdyIHTPILEIKKGKEE---PQSSLYQIYK 154

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446701131 156 EKITLKELDYKLRKHLIEKYGLYKTISKDGRVKISLKDGSFYNLDLRSKLKFKYMGEVIESKQIKDIEVNLK 227
Cdd:PRK13037 155 EDISLKELDYRLRERAIKQHGLYSNGLKQGQITITMKDGKSHTIDLSQKLEKERMGESIDGRQIQKILVEMK 226
PRK13035 PRK13035
superantigen-like protein SSL5; Reviewed;
1-227 4.05e-33

superantigen-like protein SSL5; Reviewed;


Pssm-ID: 171851  Cd Length: 234  Bit Score: 119.39  E-value: 4.05e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446701131   1 MKLTAIAKAALALGILTTGTLTTEVHSGHAKQNQKSVNKHDKEA--LYRYYTGKTMEMKNISALKH---GKNNLRFKFRG 75
Cdd:PRK13035   1 MKMAAIAKASLALGILATGTITSLHQTVNASEHEAKYENVTKDIfdLRDYYSGASKELKNVTGYRYskgGKHYLIFDKNR 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446701131  76 IKIQVLLPGNDKSKFQQRSYEGLDVFFVQEKRDKHDIFYTVGGVIQNNKTS--GVVSAPILNISKEKGEDAFVKGYPYYI 153
Cdd:PRK13035  81 KFTRVQIFGKDIERFKARKNPGLDIFVVKEAENRNGTVFSYGGVTKKNQDAyyDYINAPRFQIKRDEGDGIATYGRVHYI 160

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446701131 154 KKEKITLKELDYKLRKHLIEKYGLYKTISKDGRVKISLKDGSFYNLDLRSKLKFKYMGEVIESKQIKDIEVNLK 227
Cdd:PRK13035 161 YKEEISLKELDFKLRQYLIQNFDLYKKFPKDSKIKVIMKDGGYYTFELNKKLQTNRMSDVIDGRNIEKIEANIR 234
PRK13042 PRK13042
superantigen-like protein SSL4; Reviewed;
26-227 1.68e-27

superantigen-like protein SSL4; Reviewed;


Pssm-ID: 183854 [Multi-domain]  Cd Length: 291  Bit Score: 106.26  E-value: 1.68e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446701131  26 HSGHAKQNQKSVNKHDKEaLYRYYTGKTMEMKN-ISALKHGKNNLRF-----KFRGIKIQvlLPGNDKSKFQQRSYEGLD 99
Cdd:PRK13042  88 QSPTTKQVPTEINPKFKD-LRAYYTKPSLEFKNeIGIILKKWTTIRFmnvvpDYFIYKIA--LVGKDDKKYGEGVHRNVD 164

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446701131 100 VFFVQEKRDKHDIFYTVGGVIQNNkTSGVVSAPILNISKEKGEDAFVKGYP-YYIKKEKITLKELDYKLRKHLIEKYGLY 178
Cdd:PRK13042 165 VFVVLEENKYNLEKYSVGGITKSN-SKKVDHKAGVRITKEDNKGTISHDVSeFKITKEQISLKELDFKLRKQLIEKHNLY 243

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 446701131 179 KTISKdGRVKISLKDGSFYNLDLRSKLKFKYMGEVIESKQIKDIEVNLK 227
Cdd:PRK13042 244 GNVGS-GKIVIKMKNGGKYTFELHKKLQENRMADVIDGTNIDNIEVNIK 291
SSL_OB pfam09199
Staphylococcal superantigen-like OB-fold domain; This OB-fold domain folds into a ...
 43-123 2.90e-26

Staphylococcal superantigen-like OB-fold domain; This OB-fold domain folds into a five-stranded beta-barrel. Members of this family are found in various staphylococcal toxins described as staphylococcal superantigen-like (SSL) proteins that are related to the staphylococcal enterotoxins (SEs) or superantigens. These SSL proteins of which 11 have so far been characterized have a typical SE tertiary structure consisting of a distinct oligonucleotide/oligosaccharide binding (OB-fold), this domain, linked to a beta-grasp domain, family Stap_Strp_tox_C, pfam02876. SSLs do not bind to T-cell receptors or major histocompatibility complex class II molecules and do not stimulate T cells. SSLs target components of innate immunity, such as complement, Fc receptors, and myeloid cells 2,3,4,5,6,7,8]. SSL protein 7 (SSL7) is the best characterized of the SSLs and binds complement factor C5 and IgA with high affinity and inhibits the end stage of complement activation and IgA binding to FcalphaR.


Pssm-ID: 401224 [Multi-domain]  Cd Length: 84  Bit Score: 96.99  E-value: 2.90e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446701131   43 EALYRYYTGKTMEMKNISALK---HGKNNLRFKFRGIKIQVLLPGNDKSKFQQRSYEGLDVFFVQEKRDKHDIFYTVGGV 119
Cdd:pfam09199   1 KDLKAYYSKPSFELKNVSGYKekkTGKNFLNFTPNNQKYQVALLGKDKEKYKEGEHDNLDVFVVRELEDRNGRKYSVGGV 80


                  ....
gi 446701131  120 IQNN 123
Cdd:pfam09199  81 TKKN 84
PRK13335 PRK13335
superantigen-like protein SSL3; Reviewed;
31-227 8.66e-26

superantigen-like protein SSL3; Reviewed;


Pssm-ID: 139494 [Multi-domain]  Cd Length: 356  Bit Score: 102.90  E-value: 8.66e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446701131  31 KQNQKSVNKhDKEALYRYYTGKTMEMKNISALKHGK-NNLRF----KFRGIkIQVLLPGNDKSKFQQRSYEGLDVFFVQE 105
Cdd:PRK13335 158 KQAQTDMTP-KYEDLRAYYTKPSFEFEKQFGFLLKPwTTVRFmnviPNRFI-YKIALVGKDEKKYKDGPYDNIDVFIVLE 235

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446701131 106 KRDKHDIFYTVGGVIQNNKTSgVVSAPILNISKEKGEDAFVKGYP-YYIKKEKITLKELDYKLRKHLIEKYGLYKTISKd 184
Cdd:PRK13335 236 DNKYQLKKYSVGGITKTNSKK-VDHKAELSITKKDNQGMISRDVSeYMITKEEISLKELDFKLRKQLIEKHNLYGNMGS- 313

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 446701131 185 GRVKISLKDGSFYNLDLRSKLKFKYMGEVIESKQIKDIEVNLK 227
Cdd:PRK13335 314 GTIVIKMKNGGKYTFELHKKLQEHRMADVIDGTNIDKIEVNIK 356
PRK13041 PRK13041
superantigen-like protein SSL2; Reviewed;
1-227 1.18e-20

superantigen-like protein SSL2; Reviewed;


Pssm-ID: 106078  Cd Length: 231  Bit Score: 86.61  E-value: 1.18e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446701131   1 MKLTAIAKAALALGILTTGTLTTEVHSGHAKQNQKSVNKHDKEaLYRYYTGKTMEMKN----ISALKHGKNNLRFKFRGI 76
Cdd:PRK13041   1 MKMKNIAKISLLLGILATGVNTTTEKPVHAEKKPIVISENSKK-LKAYYTQPSIEYKNvtgyISFIQPSIKFMNIIDGNS 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446701131  77 KIQVLLPGNDKSKFQQRSYEGLDVFFVQEKRDKHDIFYTVGGVIQ-NNKTSGVVSAPILNISKEKGEDAFvKGYPYYIKK 155
Cdd:PRK13041  80 VNNLALIGKDKQHYHTGVHRNLNIFYVNEDKRFEGAKYSIGGITSaNDKAVDLIAEARVIKADHIGEYDY-DFFPFKIDK 158

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446701131 156 EKITLKELDYKLRKHLIEKYGLYKTISKdGRVKISLKDGSFYNLDLRSKLKFKYMGEVIESKQIKDIEVNLK 227
Cdd:PRK13041 159 EAMSLKEIDFKLRKYLIDNYGLYGEMST-GKITVKKKYYGKYTFELDKKLQEDRMSDVINVTDIDRIEIKVR 229
PRK13040 PRK13040
superantigen-like protein SSL6; Reviewed;
1-227 1.91e-20

superantigen-like protein SSL6; Reviewed;


Pssm-ID: 106077  Cd Length: 231  Bit Score: 85.93  E-value: 1.91e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446701131   1 MKLTAIAKAALALGILTTGTLTTEvhSGHAKQNQKSVNKHDKEALYRYYTGKTMEMKNISAL--KHGKNNLRFKFRGIK- 77
Cdd:PRK13040   1 MKLKTLAKATLVLGLLATGVITTE--SQTVKAAESTQGQHNYKSLKYYYSKPSIELKNLDGLyrQKVTDKGVYVWKDRKd 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446701131  78 IQVLLPGNDKSKFQQRSYEGLDVFFVQEKRDKHDIFYTVGGVIQNNKTSGVVSAPILNISKEKGEDAFVKGYPYYIKKEK 157
Cdd:PRK13040  79 YFVGLLGKDIEKYPQGEHDKQDAFLVIEEETVNGRQYSIGGLSKTNSKEFSKEVDVKVTRKIDESSEKSKDSKFKITKEE 158

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446701131 158 ITLKELDYKLRKHLIEKYGLYKTIS-KDGRVKISLKDGSFYNLDLRSKLKFKYMGEVIESKQIKDIEVNLK 227
Cdd:PRK13040 159 ISLKELDFKLRKKLMEEEKLYGAVNnRKGKIVVKMEDDKFYTFELTKKLQPHRMGDTIDGTKIKEINVELE 229
PRK13349 PRK13349
superantigen-like protein SSL13; Reviewed;
134-227 1.74e-07

superantigen-like protein SSL13; Reviewed;


Pssm-ID: 106307  Cd Length: 241  Bit Score: 50.44  E-value: 1.74e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446701131 134 LNISKEKGEDAFVKGYPYYI-KKEKITLKELDYKLRKHLIEKYGLYKTISKDGRVKISLKDGSfYNLDLRSKLKFKYMGE 212
Cdd:PRK13349 145 LNVTYKDKAETFTGGFPVYEgNKPVLTLKELDFRIRQTLIKSKKLYNNSYNKGQIKITGADNN-YTIDLSKRLPSTDANR 223

                         90
                 ....*....|....*
gi 446701131 213 VIESKQIKDIEVNLK 227
Cdd:PRK13349 224 YVKKPQNAKIEVILE 238
PRK13043 PRK13043
superantigen-like protein SSL14; Reviewed;
142-227 2.04e-05

superantigen-like protein SSL14; Reviewed;


Pssm-ID: 171855  Cd Length: 241  Bit Score: 44.31  E-value: 2.04e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446701131 142 EDAFVKGYPYYI-KKEKITLKELDYKLRKHLIEKYGLYKTISKDGRVKISlKDGSFYNLDLRSKLKFKYMGEVIESKQIK 220
Cdd:PRK13043 153 QQTIIGGHEFYKgNKPVLTLKELDFRIRQTLIKNKKLYNGEFNKGQIKIT-ADGNNYTIDLSKKLKLTDTNRYVKNPKNA 231


                 ....*..
gi 446701131 221 DIEVNLK 227
Cdd:PRK13043 232 QIEVILE 238
PRK13350 PRK13350
superantigen-like protein SSL12; Reviewed;
151-227 2.63e-05

superantigen-like protein SSL12; Reviewed;


Pssm-ID: 171995 [Multi-domain]  Cd Length: 238  Bit Score: 43.80  E-value: 2.63e-05
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446701131 151 YYIKKEKITLKELDYKLRKHLIEKYGLYKTISKDGRVKISLKDGSFyNLDLRSKLKFKYMGEVIESKQIKDIEVNLK 227
Cdd:PRK13350 163 YQGNKPVLTLKEIDFRAREALIKNKILYNENRNKGKLKITGGGNNY-TIDLSKRLHSDLANVYVKNPNKITVDVLFD 238
Stap_Strp_tox_C pfam02876
Staphylococcal/Streptococcal toxin, beta-grasp domain;
153-219 1.47e-04

Staphylococcal/Streptococcal toxin, beta-grasp domain;


Pssm-ID: 427030  Cd Length: 107  Bit Score: 39.99  E-value: 1.47e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446701131  153 IKKEKITLKELDYKLRKHLIEKYGLYKTISKD---GRVKISLKDGS-----FYNL---DLRSKLKFKYMGEVIESKQI 219
Cdd:pfam02876  23 TKKKIVTAQELDIKLRKLLIEKYDIYNEQEGDiskGTVKLDLDDEKdiefdFYNFggeDFNEMLKIYADNERIDSDKF 100
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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