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Conserved domains on  [gi|446686412|ref|WP_000763758|]
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MULTISPECIES: FMN-binding protein MioC [Escherichia]

Protein Classification

FMN-binding protein MioC( domain architecture ID 10013133)

FMN-binding flavoprotein MioC is involved in cofactor binding and electron transfer in biotin biosynthesis

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK09004 PRK09004
FMN-binding protein MioC; Provisional
 1-146 1.00e-93

FMN-binding protein MioC; Provisional


:

Pssm-ID: 181608 [Multi-domain]  Cd Length: 146  Bit Score: 267.08  E-value: 1.00e-93
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446686412   1 MADITLISGSTLGGAEYVAEHLAEKLEETGLTTETLHGPLLEDLSASGIWLVISSTHGAGDIPDNLSPFYEALQEQKPDL 80
Cdd:PRK09004   1 MADITLISGSTLGGAEYVADHLAEKLEEAGFSTETLHGPLLDDLSASGLWLIVTSTHGAGDLPDNLQPFFEELQEQKPDL 80

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446686412  81 SAVRFGAIGIGSREYDTFCGAIDKIEAELKNSGAKQTGETLKINILDHDIPEDPAEEWLGSWINLL 146
Cdd:PRK09004  81 SQVRFAAIGIGSSEYDTFCGAIDKLEQLLKAKGAKQIGETLKIDVLQHPIPEDPAEEWLKSWINLL 146
 
Name Accession Description Interval E-value
PRK09004 PRK09004
FMN-binding protein MioC; Provisional
 1-146 1.00e-93

FMN-binding protein MioC; Provisional


Pssm-ID: 181608 [Multi-domain]  Cd Length: 146  Bit Score: 267.08  E-value: 1.00e-93
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446686412   1 MADITLISGSTLGGAEYVAEHLAEKLEETGLTTETLHGPLLEDLSASGIWLVISSTHGAGDIPDNLSPFYEALQEQKPDL 80
Cdd:PRK09004   1 MADITLISGSTLGGAEYVADHLAEKLEEAGFSTETLHGPLLDDLSASGLWLIVTSTHGAGDLPDNLQPFFEELQEQKPDL 80

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446686412  81 SAVRFGAIGIGSREYDTFCGAIDKIEAELKNSGAKQTGETLKINILDHDIPEDPAEEWLGSWINLL 146
Cdd:PRK09004  81 SQVRFAAIGIGSSEYDTFCGAIDKLEQLLKAKGAKQIGETLKIDVLQHPIPEDPAEEWLKSWINLL 146
Flavodoxin_1 pfam00258
Flavodoxin;
6-138 9.51e-27

Flavodoxin;


Pssm-ID: 425562 [Multi-domain]  Cd Length: 142  Bit Score: 97.44  E-value: 9.51e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446686412    6 LISGSTLGGAEYVAEHLAEKLEETGLTTETLHGPLLE----DLSASGIWLVISSTHGAGDIPDNLSPFYEALQEQK---- 77
Cdd:pfam00258   1 IFYGSQTGNTEKLAEAIAEGLGEAGFEVDVVDLDDVDetlsEIEEEDLLLVVVSTWGEGEPPDNAKPFVDWLLLFGtled 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446686412   78 PDLSAVRFGAIGIGSREYDTFCGAIDKIEAELKNSGAKQTGETLKINILD-HDIPEDPAEEW 138
Cdd:pfam00258  81 GDLSGLKYAVFGLGDSGYEGFCGAAKKLDEKLSELGASRVGPLGEGDEDPqEDGLEEAFEAW 142
CysJ COG0369
Flavoprotein (flavin reductase) subunit CysJ of sulfite and N-hydroxylaminopurine reductases ...
 4-147 1.38e-23

Flavoprotein (flavin reductase) subunit CysJ of sulfite and N-hydroxylaminopurine reductases [Nucleotide transport and metabolism, Inorganic ion transport and metabolism]; Flavoprotein (flavin reductase) subunit CysJ of sulfite and N-hydroxylaminopurine reductases is part of the Pathway/BioSystem: Cysteine biosynthesis


Pssm-ID: 440138 [Multi-domain]  Cd Length: 561  Bit Score: 95.21  E-value: 1.38e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446686412   4 ITLISGSTLGGAEYVAEHLAEKLEETGLTTETLhgPL----LEDLSASGIWLVISSTHGAGDIPDNLSPFYEALQEQK-P 78
Cdd:COG0369   29 LTILYGSQTGNAEGLAEQLAERAKAAGLAVTLA--SLddykPKDLAKEGLLLIVTSTYGEGEPPDNARAFYEFLHSKKaP 106

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446686412  79 DLSAVRFGAIGIGSREYDTFCGAIDKIEAELKNSGAKQtgetlkinIL-----DHDIpEDPAEEWLGSWINLLK 147
Cdd:COG0369  107 KLDGLRYAVLGLGDSSYETFCQTGKDFDARLEELGATR--------LLprvdcDVDY-EEAAEAWLAAVLAALA 171
 
Name Accession Description Interval E-value
PRK09004 PRK09004
FMN-binding protein MioC; Provisional
 1-146 1.00e-93

FMN-binding protein MioC; Provisional


Pssm-ID: 181608 [Multi-domain]  Cd Length: 146  Bit Score: 267.08  E-value: 1.00e-93
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446686412   1 MADITLISGSTLGGAEYVAEHLAEKLEETGLTTETLHGPLLEDLSASGIWLVISSTHGAGDIPDNLSPFYEALQEQKPDL 80
Cdd:PRK09004   1 MADITLISGSTLGGAEYVADHLAEKLEEAGFSTETLHGPLLDDLSASGLWLIVTSTHGAGDLPDNLQPFFEELQEQKPDL 80

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446686412  81 SAVRFGAIGIGSREYDTFCGAIDKIEAELKNSGAKQTGETLKINILDHDIPEDPAEEWLGSWINLL 146
Cdd:PRK09004  81 SQVRFAAIGIGSSEYDTFCGAIDKLEQLLKAKGAKQIGETLKIDVLQHPIPEDPAEEWLKSWINLL 146
PRK08105 PRK08105
flavodoxin; Provisional
 1-147 8.44e-35

flavodoxin; Provisional


Pssm-ID: 181230 [Multi-domain]  Cd Length: 149  Bit Score: 118.07  E-value: 8.44e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446686412   1 MADITLISGSTLGGAEYVAEHLAEKLEETGLTTETLHGPLLEDL--SASGIWLVISSTHGAGDIPDNLSPFYEALQEQKP 78
Cdd:PRK08105   1 MAKVGIFVGTVYGNALLVAEEAEAILTAQGHEVTLFEDPELSDWqpYQDELVLVVTSTTGQGDLPDSIVPLFQALKDTAG 80

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446686412  79 DLSAVRFGAIGIGSREYDTFCGAIDKIEAELKNSGAKQTGETLKINILDHDIPEDPAEEWLGSWINLLK 147
Cdd:PRK08105  81 YQPNLRYGVIALGDSSYDNFCGAGKQFDALLQEQGAKRVGERLEIDACETPEPEVEANPWVEQWGTLLS 149
Flavodoxin_1 pfam00258
Flavodoxin;
6-138 9.51e-27

Flavodoxin;


Pssm-ID: 425562 [Multi-domain]  Cd Length: 142  Bit Score: 97.44  E-value: 9.51e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446686412    6 LISGSTLGGAEYVAEHLAEKLEETGLTTETLHGPLLE----DLSASGIWLVISSTHGAGDIPDNLSPFYEALQEQK---- 77
Cdd:pfam00258   1 IFYGSQTGNTEKLAEAIAEGLGEAGFEVDVVDLDDVDetlsEIEEEDLLLVVVSTWGEGEPPDNAKPFVDWLLLFGtled 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446686412   78 PDLSAVRFGAIGIGSREYDTFCGAIDKIEAELKNSGAKQTGETLKINILD-HDIPEDPAEEW 138
Cdd:pfam00258  81 GDLSGLKYAVFGLGDSGYEGFCGAAKKLDEKLSELGASRVGPLGEGDEDPqEDGLEEAFEAW 142
CysJ COG0369
Flavoprotein (flavin reductase) subunit CysJ of sulfite and N-hydroxylaminopurine reductases ...
 4-147 1.38e-23

Flavoprotein (flavin reductase) subunit CysJ of sulfite and N-hydroxylaminopurine reductases [Nucleotide transport and metabolism, Inorganic ion transport and metabolism]; Flavoprotein (flavin reductase) subunit CysJ of sulfite and N-hydroxylaminopurine reductases is part of the Pathway/BioSystem: Cysteine biosynthesis


Pssm-ID: 440138 [Multi-domain]  Cd Length: 561  Bit Score: 95.21  E-value: 1.38e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446686412   4 ITLISGSTLGGAEYVAEHLAEKLEETGLTTETLhgPL----LEDLSASGIWLVISSTHGAGDIPDNLSPFYEALQEQK-P 78
Cdd:COG0369   29 LTILYGSQTGNAEGLAEQLAERAKAAGLAVTLA--SLddykPKDLAKEGLLLIVTSTYGEGEPPDNARAFYEFLHSKKaP 106

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446686412  79 DLSAVRFGAIGIGSREYDTFCGAIDKIEAELKNSGAKQtgetlkinIL-----DHDIpEDPAEEWLGSWINLLK 147
Cdd:COG0369  107 KLDGLRYAVLGLGDSSYETFCQTGKDFDARLEELGATR--------LLprvdcDVDY-EEAAEAWLAAVLAALA 171
FldA COG0716
Flavodoxin [Energy production and conversion]; Flavodoxin is part of the Pathway/BioSystem: ...
 4-142 5.36e-23

Flavodoxin [Energy production and conversion]; Flavodoxin is part of the Pathway/BioSystem: Heme biosynthesis


Pssm-ID: 440480 [Multi-domain]  Cd Length: 135  Bit Score: 87.65  E-value: 5.36e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446686412   4 ITLISGSTLGGAEYVAEHLAEKLEETGLTTETLHGPLLEDLSASGIWLVISSTHgAGDIPDNLSPFYEALQEqkpDLSAV 83
Cdd:COG0716    1 ILIVYGSTTGNTEKVAEAIAEALGAAGVDLFEIEDADLDDLEDYDLLILGTPTW-AGELPDDWEDFLEELKE---DLSGK 76

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446686412  84 RFGAIGIG-SREYDTfcgAIDKIEAELKNSGAKQTGE-TLKINILDH-DIPEDPAEEWLGSW 142
Cdd:COG0716   77 KVALFGTGdSSGYGD---ALGELKELLEEKGAKVVGGyDFEGSKAPDaEDTEERAEEWLKQL 135
PRK05723 PRK05723
flavodoxin; Provisional
 4-147 1.48e-19

flavodoxin; Provisional


Pssm-ID: 168208  Cd Length: 151  Bit Score: 79.07  E-value: 1.48e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446686412   4 ITLISGSTLGGAEYVAEHLAEKLEETGLttETLHGP--LLEDLSASG--IWLVISSTHGAGDIPDNLSPFYEALQEQKPD 79
Cdd:PRK05723   3 VAILSGSVYGTAEEVARHAESLLKAAGF--EAWHNPraSLQDLQAFApeALLAVTSTTGMGELPDNLMPLYSAIRDQLPA 80

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446686412  80 -LSAVRFGAIGIGSREY-DTFCGAIDKIEAELKNSGAKQTGETLKINILDHDIPEDPAEEWLGSWINLLK 147
Cdd:PRK05723  81 aWRGLPGAVIALGDSSYgDTFCGGGEQMRELFAELGVREVQPMLRLDASETVTPETDAEPWLAEFAAALK 150
PRK07308 PRK07308
flavodoxin; Validated
 1-130 9.62e-18

flavodoxin; Validated


Pssm-ID: 180922 [Multi-domain]  Cd Length: 146  Bit Score: 74.44  E-value: 9.62e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446686412   1 MADITLISGSTLGGAEYVAEHLAEKLEETGLTTETLHGPLL--EDLSASGIWLVISSTHGAGDIPDNLSPFYEALQEQkp 78
Cdd:PRK07308   1 MALAKIVYASMTGNTEEIADIVADKLRELGHDVDVDECTTVdaSDFEDADIAIVATYTYGDGELPDEIVDFYEDLADL-- 78

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....
gi 446686412  79 DLSAVRFGAIGIGSREYDTFCGAIDKIEAELKNSGAKQTGETLKINIL--DHDI 130
Cdd:PRK07308  79 DLSGKIYGVVGSGDTFYDYFCKSVDDFEAQFALTGATKGAESVKVDLAaeDEDI 132
PRK06703 PRK06703
flavodoxin; Provisional
 1-133 1.47e-10

flavodoxin; Provisional


Pssm-ID: 235854 [Multi-domain]  Cd Length: 151  Bit Score: 55.92  E-value: 1.47e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446686412   1 MADITLISGSTLGGAEYVAEHLAEKLEETGLTTETLH--GPLLEDLSASGIWLVISSTHGAGDIPDNLSPFYEALQEQkp 78
Cdd:PRK06703   1 MAKILIAYASMSGNTEDIADLIKVSLDAFDHEVVLQEmdGMDAEELLAYDGIILGSYTWGDGDLPYEAEDFHEDLENI-- 78

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 446686412  79 DLSAVRFGAIGIGSREYDTFCGAIDKIEAELKNSGAKQTGETLKINiLDHDIPED 133
Cdd:PRK06703  79 DLSGKKVAVFGSGDTAYPLFCEAVTIFEERLVERGAELVQEGLKIE-LAPETDED 132
cysJ PRK10953
NADPH-dependent assimilatory sulfite reductase flavoprotein subunit;
1-147 1.37e-07

NADPH-dependent assimilatory sulfite reductase flavoprotein subunit;


Pssm-ID: 182862 [Multi-domain]  Cd Length: 600  Bit Score: 49.33  E-value: 1.37e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446686412   1 MADITLISGSTLGGAEYVAEHLAEKLEETGLTTETLHGP--LLEDLSASGIWLVISSTHGAGDIPDNLSPFYEALQEQK- 77
Cdd:PRK10953  61 MPGITLISASQTGNARRVAEQLRDDLLAAKLNVNLVNAGdyKFKQIAQEKLLIVVTSTQGEGEPPEEAVALHKFLFSKKa 140

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446686412  78 PDLSAVRFGAIGIGSREYDTFCGAIDKIEAELKNSGAKQTGETlkiniLDHDIP-EDPAEEWLGSWINLLK 147
Cdd:PRK10953 141 PKLENTAFAVFGLGDTSYEFFCQAGKDFDSKLAELGAERLLDR-----VDADVEyQAAASEWRARVVDALK 206
PRK06756 PRK06756
flavodoxin; Provisional
 1-125 2.25e-07

flavodoxin; Provisional


Pssm-ID: 168663 [Multi-domain]  Cd Length: 148  Bit Score: 47.18  E-value: 2.25e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446686412   1 MADITLISGSTLGGAEYVAEHLAEKLEETGL---TTETLHGPLLEDLSASGIWLVISSTHGAGDIPDNLSPFYEALqeQK 77
Cdd:PRK06756   1 MSKLVMIFASMSGNTEEMADHIAGVIRETENeieVIDIMDSPEASILEQYDGIILGAYTWGDGDLPDDFLDFYDAM--DS 78

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*...
gi 446686412  78 PDLSAVRFGAIGIGSREYDTFCGAIDKIEAELKNSGAKQTGETLKINI 125
Cdd:PRK06756  79 IDLTGKKAAVFGSCDSAYPKYGVAVDILIEKLQERGAAVVLEGLKVEL 126
PRK09267 PRK09267
flavodoxin FldA; Validated
 1-120 1.41e-06

flavodoxin FldA; Validated


Pssm-ID: 236439 [Multi-domain]  Cd Length: 169  Bit Score: 45.21  E-value: 1.41e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446686412   1 MADITLISGSTLGGAEYVAEHLAEKLEETGLTTETLHGPLLEDLSASGIWLVISSTHGAGDIPDNLSPFYEALQEqkPDL 80
Cdd:PRK09267   1 MAKIGIFFGSDTGNTEDIAKMIQKKLGKDVADVVDIAKASKEDFEAYDLLILGIPTWGYGELQCDWDDFLPELEE--IDF 78

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|..
gi 446686412  81 SAVRFGAIGIGSRE-Y-DTFCGAIDKIEAELKNSGAKQTGET 120
Cdd:PRK09267  79 SGKKVALFGLGDQEdYaEYFCDAMGTLYDIVEPRGATIVGHW 120
NorV COG0426
Flavorubredoxin [Energy production and conversion];
4-124 7.59e-05

Flavorubredoxin [Energy production and conversion];


Pssm-ID: 440195 [Multi-domain]  Cd Length: 390  Bit Score: 41.36  E-value: 7.59e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446686412   4 ITLISGSTLGGAEYVAEHLAEKLEETGLTTE------TLHGPLLEDLSASGIWLVISSTHGAGDIPdnlsPFYEALQEQK 77
Cdd:COG0426  249 VVIVYASMYGNTEKMAEAIAEGLTEEGVKVKlydlekTDPSEIITEIFDAKGIVIGSPTYNGGAFP----PIADLLGYLK 324

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*..
gi 446686412  78 PDLSAVRFGAIgIGSreYDTFCGAIDKIEAELKNSGAKQTGETLKIN 124
Cdd:COG0426  325 GLAPKNKLAGA-FGS--YGWSGEAVKLLEEKLEDAGFEVVFEPLRVK 368
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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