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Conserved domains on  [gi|446685206|ref|WP_000762552|]
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MULTISPECIES: DUF2800 domain-containing protein [Staphylococcus]

Protein Classification

DUF2800 domain-containing protein( domain architecture ID 10566908)

DUF2800 domain-containing protein may function as a nuclease

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
DUF2800 pfam10926
Protein of unknown function (DUF2800); This is a family of uncharacterized proteins found in ...
10-375 0e+00

Protein of unknown function (DUF2800); This is a family of uncharacterized proteins found in bacteria and viruses. Some members of this family are annotated as being Phi APSE P51-like proteins.


:

Pssm-ID: 431537  Cd Length: 366  Bit Score: 551.83  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446685206   10 HAKLSASGAKQWLNCPPSIKASEGIADKSTVFAEEGTFAHELSELYFSLKYEGLTQFEFNKAFQnyKRNQYYSEELREYV 89
Cdd:pfam10926   1 HALLSASSAHRWLNCPPSARLEEGFPDKTSEYAEEGTLAHELAELKLRKALGAISKRPFNSELK--KRNEYYSEEMDEYT 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446685206   90 EEYVANVEEKYNEALSRDNDVIALFETKLDLGKYVPESFGTGDVIIFSGGVLEIIDLKYGKGIEVSAIDNPQLRLYGLGA 169
Cdd:pfam10926  79 DDYVDFVIEQIEEAKETCSDPFVLVEQRLDFSPYVPEGFGTGDCVIIADDTLHIIDLKYGKGVKVSAEGNPQMMLYALGA 158
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446685206  170 YELLSLMYDIHTIRMTIIQPRIDNFSTEELPISRLLQWGADFVKPLARLAYNGGGEFKAGSHCRFCKINHSCRTRAEYMQ 249
Cdd:pfam10926 159 LEEFDILYDIKTVRMTIVQPRLDNISTWEISVEELLEWAEEVLKPKAELAFEGEGEFKPGEHCRFCKAKATCRARAEENL 238
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446685206  250 NVPQ---KPPHLLSDEEIAELLYKLPDIKKWADEVEQYALNQAkENDKNYPGWKLVEGRSRRMITDTKAMLEKLVEAGYK 326
Cdd:pfam10926 239 KLAKydfKDPPLLTDEEIAEILSKADELVSWAKDVEEYALAAA-LNGKEWPGFKLVEGRSNRKYTDEDAVADALKAAGYD 317
                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*....
gi 446685206  327 PEDITETKLLSITNLEKLIGKKAFSKITEGFIEKPQGKLTLATESDKRP 375
Cdd:pfam10926 318 EEQIYEKKLLGITAMEKLLGKKKFKELLGDLIIKPPGKPTLVPESDKRP 366
 
Name Accession Description Interval E-value
DUF2800 pfam10926
Protein of unknown function (DUF2800); This is a family of uncharacterized proteins found in ...
10-375 0e+00

Protein of unknown function (DUF2800); This is a family of uncharacterized proteins found in bacteria and viruses. Some members of this family are annotated as being Phi APSE P51-like proteins.


Pssm-ID: 431537  Cd Length: 366  Bit Score: 551.83  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446685206   10 HAKLSASGAKQWLNCPPSIKASEGIADKSTVFAEEGTFAHELSELYFSLKYEGLTQFEFNKAFQnyKRNQYYSEELREYV 89
Cdd:pfam10926   1 HALLSASSAHRWLNCPPSARLEEGFPDKTSEYAEEGTLAHELAELKLRKALGAISKRPFNSELK--KRNEYYSEEMDEYT 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446685206   90 EEYVANVEEKYNEALSRDNDVIALFETKLDLGKYVPESFGTGDVIIFSGGVLEIIDLKYGKGIEVSAIDNPQLRLYGLGA 169
Cdd:pfam10926  79 DDYVDFVIEQIEEAKETCSDPFVLVEQRLDFSPYVPEGFGTGDCVIIADDTLHIIDLKYGKGVKVSAEGNPQMMLYALGA 158
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446685206  170 YELLSLMYDIHTIRMTIIQPRIDNFSTEELPISRLLQWGADFVKPLARLAYNGGGEFKAGSHCRFCKINHSCRTRAEYMQ 249
Cdd:pfam10926 159 LEEFDILYDIKTVRMTIVQPRLDNISTWEISVEELLEWAEEVLKPKAELAFEGEGEFKPGEHCRFCKAKATCRARAEENL 238
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446685206  250 NVPQ---KPPHLLSDEEIAELLYKLPDIKKWADEVEQYALNQAkENDKNYPGWKLVEGRSRRMITDTKAMLEKLVEAGYK 326
Cdd:pfam10926 239 KLAKydfKDPPLLTDEEIAEILSKADELVSWAKDVEEYALAAA-LNGKEWPGFKLVEGRSNRKYTDEDAVADALKAAGYD 317
                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*....
gi 446685206  327 PEDITETKLLSITNLEKLIGKKAFSKITEGFIEKPQGKLTLATESDKRP 375
Cdd:pfam10926 318 EEQIYEKKLLGITAMEKLLGKKKFKELLGDLIIKPPGKPTLVPESDKRP 366
Slr0479 COG2887
RecB family exonuclease [Replication, recombination and repair];
12-242 2.91e-08

RecB family exonuclease [Replication, recombination and repair];


Pssm-ID: 442133 [Multi-domain]  Cd Length: 248  Bit Score: 54.27  E-value: 2.91e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446685206  12 KLSASGAKQWLNCPPSIKAS--EGIADK---STVFAEEGTFAHELSELYFSLKYEGLTQFEFNKAFQNY---------KR 77
Cdd:COG2887    2 RLSPSRIETLLRCPLRYYARyiLGLRDPlepPPDAADRGTLVHAVLERFYKLPADELPAEELLALLEEAwaelgfedpWA 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446685206  78 NQYYSEELREYVEEYVAnveekyNEALSRDNDVIAL---FETKLDLGkyvpesfgtgdvIIFSG----------GVLEII 144
Cdd:COG2887   82 AALWLERAERLLEAFLE------WERAPAGLEPVAVeveFELELPGG------------VRLRGridridrlpdGRLVVV 143
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446685206 145 DLKYGKGIEVSAI--DNPQLRLYGLGAYELLslmYDIHTIRMTIIQPRIDNFSTEELPISRLLQWGADFVKPLARLAYNG 222
Cdd:COG2887  144 DYKTGKAPSTKDEagEDPQLALYALALERGF---EGLVPAGARLVYLGDLGKKKVLDPLEEELEEAEERLEELAAAIADP 220
                        250       260
                 ....*....|....*....|...
gi 446685206 223 GGEFKA---GSHCRFCKINHSCR 242
Cdd:COG2887  221 EGPFPArpnPPLCRYCDYRHLCR 243
 
Name Accession Description Interval E-value
DUF2800 pfam10926
Protein of unknown function (DUF2800); This is a family of uncharacterized proteins found in ...
10-375 0e+00

Protein of unknown function (DUF2800); This is a family of uncharacterized proteins found in bacteria and viruses. Some members of this family are annotated as being Phi APSE P51-like proteins.


Pssm-ID: 431537  Cd Length: 366  Bit Score: 551.83  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446685206   10 HAKLSASGAKQWLNCPPSIKASEGIADKSTVFAEEGTFAHELSELYFSLKYEGLTQFEFNKAFQnyKRNQYYSEELREYV 89
Cdd:pfam10926   1 HALLSASSAHRWLNCPPSARLEEGFPDKTSEYAEEGTLAHELAELKLRKALGAISKRPFNSELK--KRNEYYSEEMDEYT 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446685206   90 EEYVANVEEKYNEALSRDNDVIALFETKLDLGKYVPESFGTGDVIIFSGGVLEIIDLKYGKGIEVSAIDNPQLRLYGLGA 169
Cdd:pfam10926  79 DDYVDFVIEQIEEAKETCSDPFVLVEQRLDFSPYVPEGFGTGDCVIIADDTLHIIDLKYGKGVKVSAEGNPQMMLYALGA 158
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446685206  170 YELLSLMYDIHTIRMTIIQPRIDNFSTEELPISRLLQWGADFVKPLARLAYNGGGEFKAGSHCRFCKINHSCRTRAEYMQ 249
Cdd:pfam10926 159 LEEFDILYDIKTVRMTIVQPRLDNISTWEISVEELLEWAEEVLKPKAELAFEGEGEFKPGEHCRFCKAKATCRARAEENL 238
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446685206  250 NVPQ---KPPHLLSDEEIAELLYKLPDIKKWADEVEQYALNQAkENDKNYPGWKLVEGRSRRMITDTKAMLEKLVEAGYK 326
Cdd:pfam10926 239 KLAKydfKDPPLLTDEEIAEILSKADELVSWAKDVEEYALAAA-LNGKEWPGFKLVEGRSNRKYTDEDAVADALKAAGYD 317
                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*....
gi 446685206  327 PEDITETKLLSITNLEKLIGKKAFSKITEGFIEKPQGKLTLATESDKRP 375
Cdd:pfam10926 318 EEQIYEKKLLGITAMEKLLGKKKFKELLGDLIIKPPGKPTLVPESDKRP 366
Slr0479 COG2887
RecB family exonuclease [Replication, recombination and repair];
12-242 2.91e-08

RecB family exonuclease [Replication, recombination and repair];


Pssm-ID: 442133 [Multi-domain]  Cd Length: 248  Bit Score: 54.27  E-value: 2.91e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446685206  12 KLSASGAKQWLNCPPSIKAS--EGIADK---STVFAEEGTFAHELSELYFSLKYEGLTQFEFNKAFQNY---------KR 77
Cdd:COG2887    2 RLSPSRIETLLRCPLRYYARyiLGLRDPlepPPDAADRGTLVHAVLERFYKLPADELPAEELLALLEEAwaelgfedpWA 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446685206  78 NQYYSEELREYVEEYVAnveekyNEALSRDNDVIAL---FETKLDLGkyvpesfgtgdvIIFSG----------GVLEII 144
Cdd:COG2887   82 AALWLERAERLLEAFLE------WERAPAGLEPVAVeveFELELPGG------------VRLRGridridrlpdGRLVVV 143
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446685206 145 DLKYGKGIEVSAI--DNPQLRLYGLGAYELLslmYDIHTIRMTIIQPRIDNFSTEELPISRLLQWGADFVKPLARLAYNG 222
Cdd:COG2887  144 DYKTGKAPSTKDEagEDPQLALYALALERGF---EGLVPAGARLVYLGDLGKKKVLDPLEEELEEAEERLEELAAAIADP 220
                        250       260
                 ....*....|....*....|...
gi 446685206 223 GGEFKA---GSHCRFCKINHSCR 242
Cdd:COG2887  221 EGPFPArpnPPLCRYCDYRHLCR 243
PDDEXK_1 pfam12705
PD-(D/E)XK nuclease superfamily; Members of this family belong to the PD-(D/E)XK nuclease ...
13-242 3.68e-06

PD-(D/E)XK nuclease superfamily; Members of this family belong to the PD-(D/E)XK nuclease superfamily


Pssm-ID: 432731 [Multi-domain]  Cd Length: 250  Bit Score: 47.91  E-value: 3.68e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446685206   13 LSASGAKQWLNCPPSIKAS--EGI-ADKSTVFAEEGTFAHELSELYFSLKYEGLTQFE------FNKAFQN-------YK 76
Cdd:pfam12705   2 LSPSRLETYLTCPLRFFLRylLGLrEDEELDAPDLGTLVHAALERFYRWGRLPEEDLEellqalLEELWPElglqseiLP 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446685206   77 RNQYYSEELREYVEEYVANVEEKynEALSRDNDVIAlFETKLDL------GKYvpesfgtgDVIIFS-GGVLEIIDLKYG 149
Cdd:pfam12705  82 RLPWLAGRLRRRLERMLRRLAEW--LRARRGFRPVA-VELGFGGttvrlvGRI--------DRVDLDgEGYLRIIDYKTG 150
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446685206  150 KGIEVS----AIDNPQLRLYGLGAYELLSlmYDIHTIRMTIIQPRIDNFSTEE------LPISRLLQWgADFVKPLARLA 219
Cdd:pfam12705 151 SAPPQSedldLYEGLQLLLYLLALAAGEK--ALGGPAGALYLRLDDPLKKDEEvvepmvLTEDEFDAL-LQELRELAEEI 227
                         250       260
                  ....*....|....*....|...
gi 446685206  220 YNGGGEFKAGSHCRFCKINHSCR 242
Cdd:pfam12705 228 LAGEFPARPGKKCRYCPYRSICP 250
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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