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Conserved domains on  [gi|446661077|ref|WP_000738423|]
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MULTISPECIES: increased serum survival lipoprotein Iss [Enterobacteriaceae]

Protein Classification

Bor family protein( domain architecture ID 10533615)

Bor family protein such as Escherichia virus Lambda lipoprotein bor and Escherichia coli protein iss that increases serum survival and confers group II surface exclusion

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
Lambda_Bor pfam06291
Bor protein; This family consists of several Bacteriophage lambda Bor and Escherichia coli Iss ...
19-95 1.06e-31

Bor protein; This family consists of several Bacteriophage lambda Bor and Escherichia coli Iss proteins. Expression of bor significantly increases the survival of the Escherichia coli host cell in animal serum. This property is a well known bacterial virulence determinant indeed, bor and its adjacent sequences are highly homologous to the iss serum resistance locus of the plasmid ColV2-K94, which confers virulence in animals. It has been suggested that lysogeny may generally have a role in bacterial survival in animal hosts, and perhaps in pathogenesis.


:

Pssm-ID: 461869  Cd Length: 77  Bit Score: 105.88  E-value: 1.06e-31
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446661077  19 QQTFTVGNKPT-AVTPKETITHHFFVSGIGQEKTVDAAKICGGAEnVVKTETQQTFVNGLLGFITLGIYTPLEARVYC 95
Cdd:pfam06291  1 TQTFVVGPVPKgAQTPTYEKSNHFFIWGLAPEKVVDAAEVCGGAG-VYQVETQTTFVNGLLGVVTLGIYTPTTTKVYC 77
 
Name Accession Description Interval E-value
Lambda_Bor pfam06291
Bor protein; This family consists of several Bacteriophage lambda Bor and Escherichia coli Iss ...
19-95 1.06e-31

Bor protein; This family consists of several Bacteriophage lambda Bor and Escherichia coli Iss proteins. Expression of bor significantly increases the survival of the Escherichia coli host cell in animal serum. This property is a well known bacterial virulence determinant indeed, bor and its adjacent sequences are highly homologous to the iss serum resistance locus of the plasmid ColV2-K94, which confers virulence in animals. It has been suggested that lysogeny may generally have a role in bacterial survival in animal hosts, and perhaps in pathogenesis.


Pssm-ID: 461869  Cd Length: 77  Bit Score: 105.88  E-value: 1.06e-31
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446661077  19 QQTFTVGNKPT-AVTPKETITHHFFVSGIGQEKTVDAAKICGGAEnVVKTETQQTFVNGLLGFITLGIYTPLEARVYC 95
Cdd:pfam06291  1 TQTFVVGPVPKgAQTPTYEKSNHFFIWGLAPEKVVDAAEVCGGAG-VYQVETQTTFVNGLLGVVTLGIYTPTTTKVYC 77
 
Name Accession Description Interval E-value
Lambda_Bor pfam06291
Bor protein; This family consists of several Bacteriophage lambda Bor and Escherichia coli Iss ...
19-95 1.06e-31

Bor protein; This family consists of several Bacteriophage lambda Bor and Escherichia coli Iss proteins. Expression of bor significantly increases the survival of the Escherichia coli host cell in animal serum. This property is a well known bacterial virulence determinant indeed, bor and its adjacent sequences are highly homologous to the iss serum resistance locus of the plasmid ColV2-K94, which confers virulence in animals. It has been suggested that lysogeny may generally have a role in bacterial survival in animal hosts, and perhaps in pathogenesis.


Pssm-ID: 461869  Cd Length: 77  Bit Score: 105.88  E-value: 1.06e-31
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446661077  19 QQTFTVGNKPT-AVTPKETITHHFFVSGIGQEKTVDAAKICGGAEnVVKTETQQTFVNGLLGFITLGIYTPLEARVYC 95
Cdd:pfam06291  1 TQTFVVGPVPKgAQTPTYEKSNHFFIWGLAPEKVVDAAEVCGGAG-VYQVETQTTFVNGLLGVVTLGIYTPTTTKVYC 77
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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