|
Name |
Accession |
Description |
Interval |
E-value |
| pheT |
PRK00629 |
phenylalanyl-tRNA synthetase subunit beta; Reviewed |
1-795 |
0e+00 |
|
phenylalanyl-tRNA synthetase subunit beta; Reviewed
Pssm-ID: 234804 [Multi-domain] Cd Length: 791 Bit Score: 1197.29 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446595056 1 MKFSELWLREWVNPAIDSDALANQITMAGLEVDGVEPVAGSFNGVVVGEVVECAQHPNADKLRVTKVNVGGErLLDIVCG 80
Cdd:PRK00629 1 MKFSLSWLKEYVNPDISSEELAEALTMIGLEVEGVEDVAAGLSGVVVGKVLECEKHPNADKLRVCQVDVGEE-PLQIVCG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446595056 81 APNCRQGLKVAVATIGAILPGDFKIKAAKLRGEPSEGMLCSFSELGISDDHSGIIELPADAPLGTDIREYLKLDDNTIEI 160
Cdd:PRK00629 80 APNVRAGDKVPVALPGAVLPGGFKIKKAKLRGVESEGMLCSASELGLSDDHDGIIELPEDAPVGTDAREYLGLDDTVIEI 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446595056 161 SVTPNRADCLGIIGVARDVAVLNKAPLQEPEMAPVTATISDTLPITVEAADACPRYLGRVVKGINVNAPTPLWMKEKLRR 240
Cdd:PRK00629 160 SLTPNRADCLSVRGIARELAALLGLPLKLPEIEPVPATIDDKLPVEIEDPDLCPRYAGRVIKGVKNIAPSPLWLQERLRA 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446595056 241 CGIRSIDAVVDVTNYVLLELGQPMHAFDKDRIDGGIVVRMAKEGETVVLLDGSEATLNADTLVIADHHKALGIAGIFGGE 320
Cdd:PRK00629 240 AGIRPINNVVDITNYVMLELGQPLHAFDLDKIGGGIVVRRAKEGEKLTTLDGKERTLDPEDLVIADDKKPLALAGVMGGE 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446595056 321 HSGVNGETQNVLLECAYFNPLSITGRARRHGLHTDASHRYERGVDPALQYKAIERATRLLLDICGGDAgpIIDVSNEATL 400
Cdd:PRK00629 320 DSEVTENTTNVLLESAYFDPVSIRKTARRLGLRTDASYRFERGVDPALTLLALERATALILELGGGEV--VEGVVDVYPL 397
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446595056 401 PKRATITLRRSKLDRLIGHHIADEQVSDILRRLGCEVT-EGQDEWKAVAPTWRFDMEIEEDLVEEVARVYGYNNIPDEPI 479
Cdd:PRK00629 398 PKEPTITLRLERINRLLGTEISDEEIVDILKRLGFEVTeVDGDGLTVTVPSWRFDIEIEEDLVEEVARIYGYDNIPSTPP 477
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446595056 480 QAGLIMGTHREADLSLKRVKTMLNDKGYQEVITYSFVDPKVQQLIHPGAEALLLPNPISVEMSAMRLSLWSGLLATVVYN 559
Cdd:PRK00629 478 VAALTMGGLTEAQRLLRRLRRALAALGYQEVITYSFVSPEDAKLFGLNPEPLLLLNPISEELSVMRTSLLPGLLEAVAYN 557
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446595056 560 QNRQQNRVRIFETGLRFVPDtqaNLGIRQDLMLAGVICGNRYDEHWNlAKETVDFYDLKGDLEAVLDLTGKLGDIQFKAE 639
Cdd:PRK00629 558 LNRGNKDVALFEIGRVFLPD---GDLPREPEHLAGVLTGNRVEESWG-GKRPVDFFDLKGDVEALLEALGLPEVEFVAEF 633
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446595056 640 MNPALHPGQSAAIYLKDERIGFIGVVHPELERKLDLNGRTLVFELEWNKL--ADRIVPQAREISRFPANRRDIAVVVAEN 717
Cdd:PRK00629 634 EAAALHPGRSAEIYLDGKVIGFIGELHPKVLKKLDLPGRTYVFELDLDALleAARKLPKYKPISKFPAVRRDLALVVDED 713
|
730 740 750 760 770 780 790
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446595056 718 VPAADILSECKKVGVNQVVGVNLFDVYRGKGVAEGYKSLAISLILQDTNRTLEEEEIAATVAKCVEALKERFQASLRD 795
Cdd:PRK00629 714 VPAADILKAIKKAGGKLLESVELFDVYEGKGIGEGKKSLAFRLTFQDPDRTLTDEEINAAMDKIVAALEEKFGAELRG 791
|
|
| PheT |
COG0072 |
Phenylalanyl-tRNA synthetase beta subunit [Translation, ribosomal structure and biogenesis]; ... |
1-795 |
0e+00 |
|
Phenylalanyl-tRNA synthetase beta subunit [Translation, ribosomal structure and biogenesis]; Phenylalanyl-tRNA synthetase beta subunit is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 439842 [Multi-domain] Cd Length: 793 Bit Score: 1151.06 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446595056 1 MKFSELWLREWVNPAIDSDALANQITMAGLEVDGVEPVAGSFNGVVVGEVVECAQHPNADKLRVTKVNVGGERLLDIVCG 80
Cdd:COG0072 1 MKLSLLWLLLLVEEAALLEELLLLLTGEGLEEEEVEGAAAVVVGVVVVVVVVEEPHPDADDLVVVVVDVGGGEVLVVVCG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446595056 81 APNCRQGLKVAVATIGAILPGDFKIKAAKLRGEPSEGMLCSFSELGISDDHSGIIELPADAPLGTDIREYLKLDDNTIEI 160
Cdd:COG0072 81 AANVAVGVVVVAAPGGAVLPGGFKIKKAKIRGVESSGMLCSEEELGLGEDHDGIIVLPPDAPVGGDAREYLGLDDTVLEI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446595056 161 SVTPNRADCLGIIGVARDVAVLNKAPLQEPEMAP-VTATISDTLPITVEAADACPRYLGRVVKGINVnAPTPLWMKEKLR 239
Cdd:COG0072 161 DLTPNRADCLSVRGVARELAALLGAPLKLPAIEPeVPPAIDDPIPVEIEDPEACPRYAGRVIRGVKV-GPSPLWMQERLR 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446595056 240 RCGIRSIDAVVDVTNYVLLELGQPMHAFDKDRIDGGIVVRMAKEGETVVLLDGSEATLNADTLVIADHHKALGIAGIFGG 319
Cdd:COG0072 240 AAGIRPINNVVDITNYVMLELGQPLHAFDLDKLKGGIVVRRAREGEKLTTLDGKERTLDPDDLVIADDEGPLALAGVMGG 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446595056 320 EHSGVNGETQNVLLECAYFNPLSITGRARRHGLHTDASHRYERGVDPALQYKAIERATRLLLDICGGDAGP-IIDVSNEA 398
Cdd:COG0072 320 EDSEVTEETTDVLLESAYFDPVSIRRTARRLGLHSDASYRFERGVDPALTVAALERATQLILEIAGGEVGPgIVDVYPEP 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446595056 399 tlPKRATITLRRSKLDRLIGHHIADEQVSDILRRLGCEVTEGQDEWKAVAPTWRFDMEIEEDLVEEVARVYGYNNIPDEP 478
Cdd:COG0072 400 --PEPKTITLRLARINRLLGVEIPAEEIEEILERLGFEVEEDGDGLTVTVPSWRFDIEIEADLIEEVARIYGYDNIPSTL 477
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446595056 479 IQAGLIMGTHREADLSLKRVKTMLNDKGYQEVITYSFVDPKVQQLIHPGAEALLLPNPISVEMSAMRLSLWSGLLATVVY 558
Cdd:COG0072 478 PRAPLAGGGLTEAQRLRRRVRRALAARGYQEVITYSFVSPEDADLFGLRREAVRLANPISEDLSVMRTSLLPGLLEAAAY 557
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446595056 559 NQNRQQNRVRIFETGLRFVPDTQANLgiRQDLMLAGVICGNRYDEHWNLAKETVDFYDLKGDLEAVLDLTGkLGDIQFKA 638
Cdd:COG0072 558 NLNRGQKDVRLFEIGRVFLPDEGEEP--REPLHLAGVLTGNREPESWGGKARPVDFFDLKGDVEALLAALG-VPKLEFEA 634
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446595056 639 EMNPALHPGQSAAIYLKDERIGFIGVVHPELERKLDLNGRTLVFELEWNKL--ADRIVPQAREISRFPANRRDIAVVVAE 716
Cdd:COG0072 635 AEHPALHPGRSAEILLGGKVIGFIGELHPKVLKALDLPGPVYVFELDLDALleLARKVPKYKPISKFPAVRRDLALVVDE 714
|
730 740 750 760 770 780 790
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446595056 717 NVPAADILSECKKVGVNQVVGVNLFDVYRGKGVAEGYKSLAISLILQDTNRTLEEEEIAATVAKCVEALKERFQASLRD 795
Cdd:COG0072 715 DVPAADVLDAIRKAAGKLLEDVRLFDVYEGKGVPEGKKSLAFSLTLQDPDRTLTDEEIDAAMDKIVAALEKKFGAELRG 793
|
|
| pheT_bact |
TIGR00472 |
phenylalanyl-tRNA synthetase, beta subunit, non-spirochete bacterial; Every known example of ... |
1-794 |
0e+00 |
|
phenylalanyl-tRNA synthetase, beta subunit, non-spirochete bacterial; Every known example of the phenylalanyl-tRNA synthetase, except the monomeric form of mitochondrial, is an alpha 2 beta 2 heterotetramer. The beta subunits break into two subfamilies that are considerably different in sequence, length, and pattern of gaps. This model represents the subfamily that includes the beta subunit from Bacteria other than spirochetes, as well as a chloroplast-encoded form from Porphyra purpurea. The chloroplast-derived sequence is considerably shorter at the amino end. [Protein synthesis, tRNA aminoacylation]
Pssm-ID: 273097 [Multi-domain] Cd Length: 797 Bit Score: 1019.91 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446595056 1 MKFSELWLREWVNPA-IDSDALANQITMAGLEVDGVEPVAGSFNGVVVGEVVECAQHPNADKLRVTKVNVGGERLLDIVC 79
Cdd:TIGR00472 1 MKISLKWLREYVPLSeIDNEEIAEALTSIGLEVEAVIPFSKPLKGVVVGKVLEVEPHPNADKLKVCKVDIGEKEMLQIVC 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446595056 80 GAPNCRQGLKVAVATIGAILPGDFKIKAAKLRGEPSEGMLCSFSELGISDDHSGIIELPADAPLGTDIREYLKLDDNTIE 159
Cdd:TIGR00472 81 GAPNVEAGKKVAVALPGAKLPNGLKIKKSKLRGVESEGMLCSESELGLDEKSDGIIVLDEDAPLGTDIAEYLGLDDDIIE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446595056 160 ISVTPNRADCLGIIGVARDVAVLNKAPLQEP--EMAPVTATISDTLPITVEAADACPRYLGRVVKGINVNaPTPLWMKEK 237
Cdd:TIGR00472 161 VSITPNRGDCLSILGIARELAALFDLNLETPvpFEPETTETIDEGFKIEIEDPEVCPFYLGRVIKGVKVK-PSPLWLKER 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446595056 238 LRRCGIRSIDAVVDVTNYVLLELGQPMHAFDKDRIDGGIVVRMAKEGETVVLLDGSEATLNADTLVIADHHKALGIAGIF 317
Cdd:TIGR00472 240 LRRSGIRPINNIVDITNYVMLELGQPLHAFDADKIEGNIVVRSAKEGESFTTLDGKERELKKGDLVIADDKKPLAIAGVM 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446595056 318 GGEHSGVNGETQNVLLECAYFNPLSITGRARRHGLHTDASHRYERGVDPALQYKAIERATRLLLDICGGDAGPIIdVSNE 397
Cdd:TIGR00472 320 GGKESGVTDTTTNIFLESAYFNPESIRKTARRLGISTDSSYRFERGVDPELTELALDRALNLILEIFGGEVISVV-SDNY 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446595056 398 ATLPKRATITLRRSKLDRLIGHHIADEQVSDILRRLGCEVTEGQDEWKAVAPTWRFDMEIEEDLVEEVARVYGYNNIPDE 477
Cdd:TIGR00472 399 KEKAKEKKISLRIKKLNKILGIELSDEEVRDILKRLGFKVEKQKDGWEVTVPSYRHDIEIEEDLIEEIARIYGYDNIPAE 478
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446595056 478 PIQAGLIMGTHREADLSLKRVKTMLNDKGYQEVITYSFVDP-KVQQLIHPGAEALL-LPNPISVEMSAMRLSLWSGLLAT 555
Cdd:TIGR00472 479 PLSVSSKLNKNNENYLLLRKLRTLLVGLGLNEVITYSFVDPeKAEKFNFPKLENLVeIKNPLSNERSVLRTSLLPSLLEV 558
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446595056 556 VVYNQNRQQNRVRIFETGLRFVPDtqaNLGIRQDLMLAGVICGNRYDEHWNLAKETVDFYDLKGDLEAVLDLTGKLGDIQ 635
Cdd:TIGR00472 559 LAYNQNRKNKDVKIFEIGKVFAKD---GEAVKEQLRLAILISGEKNPSSWNHKEEKVDFYDLKGDVESLLELLGLSDDVY 635
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446595056 636 FK-AEMNPALHPGQSAAIYLKDERIGFIGVVHPELERKLDLNGRTLVFELEWNKLADRI--VPQAREISRFPANRRDIAV 712
Cdd:TIGR00472 636 FKnTAENEELHPGQSATIYLKGKKIGFIGELHPEIAKKYDLKEPTFVFELDLDRLLESLkkVPKYRPISKFPAVTRDISF 715
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446595056 713 VVAENVPAADILSECKKVGVNQVVGVNLFDVYRGKGVAEGYKSLAISLILQDTNRTLEEEEIAATVAKCVEALKERFQAS 792
Cdd:TIGR00472 716 LVPKDVPANEIIKLIKKSGLELLEEVELFDVYQGKNIGEGKKSLALRLVLRDKERTLTDEEINKIVEKVLNALKEKLGAE 795
|
..
gi 446595056 793 LR 794
Cdd:TIGR00472 796 LR 797
|
|
| B3_4 |
pfam03483 |
B3/4 domain; This domain is found in tRNA synthetase beta subunits as well as in some non tRNA ... |
212-385 |
3.18e-97 |
|
B3/4 domain; This domain is found in tRNA synthetase beta subunits as well as in some non tRNA synthetase proteins.
Pssm-ID: 427327 [Multi-domain] Cd Length: 174 Bit Score: 299.46 E-value: 3.18e-97
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446595056 212 ACPRYLGRVVKGINVNAPTPLWMKEKLRRCGIRSIDAVVDVTNYVLLELGQPMHAFDKDRIDGGIVVRMAKEGETVVLLD 291
Cdd:pfam03483 1 ACPRYFGRVIRGVKKNRPSPEWLQRRLRRAGIRPINNVVDITNYVMLELGQPLHAFDLDKIAGDIVVRLAKGGEKFTTLD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446595056 292 GSEATLNADTLVIADHHKALGIAGIFGGEHSGVNGETQNVLLECAYFNPLSITGRARRHGLHTDASHRYERGVDPALQYK 371
Cdd:pfam03483 81 GKERELDPGDLVIADDDGPVALAGIMGGEESEVTEDTTNIFLESAGFDPVAIRKTARRLGLRTDASYRFERGVDPELVEA 160
|
170
....*....|....
gi 446595056 372 AIERATRLLLDICG 385
Cdd:pfam03483 161 ALDRATALLLELCG 174
|
|
| B3_4 |
smart00873 |
B3/4 domain; This domain is found in tRNA synthetase beta subunits as well as in some non tRNA ... |
213-385 |
2.03e-78 |
|
B3/4 domain; This domain is found in tRNA synthetase beta subunits as well as in some non tRNA synthetase proteins.
Pssm-ID: 214876 [Multi-domain] Cd Length: 174 Bit Score: 249.87 E-value: 2.03e-78
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446595056 213 CPRYLGRVVKGINVNAPTPLWMKEKLRRCGIRSIDAVVDVTNYVLLELGQPMHAFDKDRIDGG-IVVRMAKEGETVVLLD 291
Cdd:smart00873 1 CPRYLGRVIRGVKNTRPSPEWLQERLHRAGIRPINNVVDITNYVSLETGQPLHAFDLDKIKGKdIPLRRAKEGEKFETLD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446595056 292 GSEATLNADTLVIADHHKALGIAGIFGGEHSGVNGETQNVLLECAYFNPLSITGRARRHGLHTDASHRYERGVDPALQYK 371
Cdd:smart00873 81 GKEYELDEGDLVIADDEGPLALAGVMGGEESEVTENTTVIFLEPAIFSPRTIRITARTLNLFTDASGRFERGVDPELVEL 160
|
170
....*....|....
gi 446595056 372 AIERATRLLLDICG 385
Cdd:smart00873 161 ALDRAAALLLEICG 174
|
|
| PheRS_beta_core |
cd00769 |
Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II ... |
495-689 |
5.96e-74 |
|
Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA, PheRS is an exception in that it attaches the amino acid at the 2'-OH group, like class I aaRSs. PheRS is an alpha-2/ beta-2 tetramer. While the alpha chain contains a catalytic core domain, the beta chain has a non-catalytic core domain.
Pssm-ID: 238392 [Multi-domain] Cd Length: 198 Bit Score: 239.08 E-value: 5.96e-74
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446595056 495 LKRVKTMLNDKGYQEVITYSFVDPKVQQLI-HPGAEALLLPNPISVEMSAMRLSLWSGLLATVVYNQNRQQNRVRIFETG 573
Cdd:cd00769 6 ERKLRRLLAGLGFQEVITYSLTSPEEAELFdGGLDEAVELSNPLSEEYSVLRTSLLPGLLDALARNLNRKNKPLRLFEIG 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446595056 574 LRFVPDtqaNLGIRQDLMLAGVICGNRYDEHWNLAKETVDFYDLKGDLEAVLDLTGKLGDIQFKAEMNPALHPGQSAAIY 653
Cdd:cd00769 86 RVFLKD---EDGPEEEEHLAALLSGNREPESWQGKGRPVDFYDAKGILEALLRALGIIVEFELEELDADLFHPGRSAKIY 162
|
170 180 190
....*....|....*....|....*....|....*.
gi 446595056 654 LKDERIGFIGVVHPELERKLDLNGRTLVFELEWNKL 689
Cdd:cd00769 163 VNGEVIGFIGELHPEVLKEFDLKEPVYAFELDLDAL 198
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| pheT |
PRK00629 |
phenylalanyl-tRNA synthetase subunit beta; Reviewed |
1-795 |
0e+00 |
|
phenylalanyl-tRNA synthetase subunit beta; Reviewed
Pssm-ID: 234804 [Multi-domain] Cd Length: 791 Bit Score: 1197.29 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446595056 1 MKFSELWLREWVNPAIDSDALANQITMAGLEVDGVEPVAGSFNGVVVGEVVECAQHPNADKLRVTKVNVGGErLLDIVCG 80
Cdd:PRK00629 1 MKFSLSWLKEYVNPDISSEELAEALTMIGLEVEGVEDVAAGLSGVVVGKVLECEKHPNADKLRVCQVDVGEE-PLQIVCG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446595056 81 APNCRQGLKVAVATIGAILPGDFKIKAAKLRGEPSEGMLCSFSELGISDDHSGIIELPADAPLGTDIREYLKLDDNTIEI 160
Cdd:PRK00629 80 APNVRAGDKVPVALPGAVLPGGFKIKKAKLRGVESEGMLCSASELGLSDDHDGIIELPEDAPVGTDAREYLGLDDTVIEI 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446595056 161 SVTPNRADCLGIIGVARDVAVLNKAPLQEPEMAPVTATISDTLPITVEAADACPRYLGRVVKGINVNAPTPLWMKEKLRR 240
Cdd:PRK00629 160 SLTPNRADCLSVRGIARELAALLGLPLKLPEIEPVPATIDDKLPVEIEDPDLCPRYAGRVIKGVKNIAPSPLWLQERLRA 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446595056 241 CGIRSIDAVVDVTNYVLLELGQPMHAFDKDRIDGGIVVRMAKEGETVVLLDGSEATLNADTLVIADHHKALGIAGIFGGE 320
Cdd:PRK00629 240 AGIRPINNVVDITNYVMLELGQPLHAFDLDKIGGGIVVRRAKEGEKLTTLDGKERTLDPEDLVIADDKKPLALAGVMGGE 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446595056 321 HSGVNGETQNVLLECAYFNPLSITGRARRHGLHTDASHRYERGVDPALQYKAIERATRLLLDICGGDAgpIIDVSNEATL 400
Cdd:PRK00629 320 DSEVTENTTNVLLESAYFDPVSIRKTARRLGLRTDASYRFERGVDPALTLLALERATALILELGGGEV--VEGVVDVYPL 397
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446595056 401 PKRATITLRRSKLDRLIGHHIADEQVSDILRRLGCEVT-EGQDEWKAVAPTWRFDMEIEEDLVEEVARVYGYNNIPDEPI 479
Cdd:PRK00629 398 PKEPTITLRLERINRLLGTEISDEEIVDILKRLGFEVTeVDGDGLTVTVPSWRFDIEIEEDLVEEVARIYGYDNIPSTPP 477
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446595056 480 QAGLIMGTHREADLSLKRVKTMLNDKGYQEVITYSFVDPKVQQLIHPGAEALLLPNPISVEMSAMRLSLWSGLLATVVYN 559
Cdd:PRK00629 478 VAALTMGGLTEAQRLLRRLRRALAALGYQEVITYSFVSPEDAKLFGLNPEPLLLLNPISEELSVMRTSLLPGLLEAVAYN 557
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446595056 560 QNRQQNRVRIFETGLRFVPDtqaNLGIRQDLMLAGVICGNRYDEHWNlAKETVDFYDLKGDLEAVLDLTGKLGDIQFKAE 639
Cdd:PRK00629 558 LNRGNKDVALFEIGRVFLPD---GDLPREPEHLAGVLTGNRVEESWG-GKRPVDFFDLKGDVEALLEALGLPEVEFVAEF 633
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446595056 640 MNPALHPGQSAAIYLKDERIGFIGVVHPELERKLDLNGRTLVFELEWNKL--ADRIVPQAREISRFPANRRDIAVVVAEN 717
Cdd:PRK00629 634 EAAALHPGRSAEIYLDGKVIGFIGELHPKVLKKLDLPGRTYVFELDLDALleAARKLPKYKPISKFPAVRRDLALVVDED 713
|
730 740 750 760 770 780 790
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446595056 718 VPAADILSECKKVGVNQVVGVNLFDVYRGKGVAEGYKSLAISLILQDTNRTLEEEEIAATVAKCVEALKERFQASLRD 795
Cdd:PRK00629 714 VPAADILKAIKKAGGKLLESVELFDVYEGKGIGEGKKSLAFRLTFQDPDRTLTDEEINAAMDKIVAALEEKFGAELRG 791
|
|
| PheT |
COG0072 |
Phenylalanyl-tRNA synthetase beta subunit [Translation, ribosomal structure and biogenesis]; ... |
1-795 |
0e+00 |
|
Phenylalanyl-tRNA synthetase beta subunit [Translation, ribosomal structure and biogenesis]; Phenylalanyl-tRNA synthetase beta subunit is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 439842 [Multi-domain] Cd Length: 793 Bit Score: 1151.06 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446595056 1 MKFSELWLREWVNPAIDSDALANQITMAGLEVDGVEPVAGSFNGVVVGEVVECAQHPNADKLRVTKVNVGGERLLDIVCG 80
Cdd:COG0072 1 MKLSLLWLLLLVEEAALLEELLLLLTGEGLEEEEVEGAAAVVVGVVVVVVVVEEPHPDADDLVVVVVDVGGGEVLVVVCG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446595056 81 APNCRQGLKVAVATIGAILPGDFKIKAAKLRGEPSEGMLCSFSELGISDDHSGIIELPADAPLGTDIREYLKLDDNTIEI 160
Cdd:COG0072 81 AANVAVGVVVVAAPGGAVLPGGFKIKKAKIRGVESSGMLCSEEELGLGEDHDGIIVLPPDAPVGGDAREYLGLDDTVLEI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446595056 161 SVTPNRADCLGIIGVARDVAVLNKAPLQEPEMAP-VTATISDTLPITVEAADACPRYLGRVVKGINVnAPTPLWMKEKLR 239
Cdd:COG0072 161 DLTPNRADCLSVRGVARELAALLGAPLKLPAIEPeVPPAIDDPIPVEIEDPEACPRYAGRVIRGVKV-GPSPLWMQERLR 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446595056 240 RCGIRSIDAVVDVTNYVLLELGQPMHAFDKDRIDGGIVVRMAKEGETVVLLDGSEATLNADTLVIADHHKALGIAGIFGG 319
Cdd:COG0072 240 AAGIRPINNVVDITNYVMLELGQPLHAFDLDKLKGGIVVRRAREGEKLTTLDGKERTLDPDDLVIADDEGPLALAGVMGG 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446595056 320 EHSGVNGETQNVLLECAYFNPLSITGRARRHGLHTDASHRYERGVDPALQYKAIERATRLLLDICGGDAGP-IIDVSNEA 398
Cdd:COG0072 320 EDSEVTEETTDVLLESAYFDPVSIRRTARRLGLHSDASYRFERGVDPALTVAALERATQLILEIAGGEVGPgIVDVYPEP 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446595056 399 tlPKRATITLRRSKLDRLIGHHIADEQVSDILRRLGCEVTEGQDEWKAVAPTWRFDMEIEEDLVEEVARVYGYNNIPDEP 478
Cdd:COG0072 400 --PEPKTITLRLARINRLLGVEIPAEEIEEILERLGFEVEEDGDGLTVTVPSWRFDIEIEADLIEEVARIYGYDNIPSTL 477
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446595056 479 IQAGLIMGTHREADLSLKRVKTMLNDKGYQEVITYSFVDPKVQQLIHPGAEALLLPNPISVEMSAMRLSLWSGLLATVVY 558
Cdd:COG0072 478 PRAPLAGGGLTEAQRLRRRVRRALAARGYQEVITYSFVSPEDADLFGLRREAVRLANPISEDLSVMRTSLLPGLLEAAAY 557
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446595056 559 NQNRQQNRVRIFETGLRFVPDTQANLgiRQDLMLAGVICGNRYDEHWNLAKETVDFYDLKGDLEAVLDLTGkLGDIQFKA 638
Cdd:COG0072 558 NLNRGQKDVRLFEIGRVFLPDEGEEP--REPLHLAGVLTGNREPESWGGKARPVDFFDLKGDVEALLAALG-VPKLEFEA 634
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446595056 639 EMNPALHPGQSAAIYLKDERIGFIGVVHPELERKLDLNGRTLVFELEWNKL--ADRIVPQAREISRFPANRRDIAVVVAE 716
Cdd:COG0072 635 AEHPALHPGRSAEILLGGKVIGFIGELHPKVLKALDLPGPVYVFELDLDALleLARKVPKYKPISKFPAVRRDLALVVDE 714
|
730 740 750 760 770 780 790
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446595056 717 NVPAADILSECKKVGVNQVVGVNLFDVYRGKGVAEGYKSLAISLILQDTNRTLEEEEIAATVAKCVEALKERFQASLRD 795
Cdd:COG0072 715 DVPAADVLDAIRKAAGKLLEDVRLFDVYEGKGVPEGKKSLAFSLTLQDPDRTLTDEEIDAAMDKIVAALEKKFGAELRG 793
|
|
| pheT_bact |
TIGR00472 |
phenylalanyl-tRNA synthetase, beta subunit, non-spirochete bacterial; Every known example of ... |
1-794 |
0e+00 |
|
phenylalanyl-tRNA synthetase, beta subunit, non-spirochete bacterial; Every known example of the phenylalanyl-tRNA synthetase, except the monomeric form of mitochondrial, is an alpha 2 beta 2 heterotetramer. The beta subunits break into two subfamilies that are considerably different in sequence, length, and pattern of gaps. This model represents the subfamily that includes the beta subunit from Bacteria other than spirochetes, as well as a chloroplast-encoded form from Porphyra purpurea. The chloroplast-derived sequence is considerably shorter at the amino end. [Protein synthesis, tRNA aminoacylation]
Pssm-ID: 273097 [Multi-domain] Cd Length: 797 Bit Score: 1019.91 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446595056 1 MKFSELWLREWVNPA-IDSDALANQITMAGLEVDGVEPVAGSFNGVVVGEVVECAQHPNADKLRVTKVNVGGERLLDIVC 79
Cdd:TIGR00472 1 MKISLKWLREYVPLSeIDNEEIAEALTSIGLEVEAVIPFSKPLKGVVVGKVLEVEPHPNADKLKVCKVDIGEKEMLQIVC 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446595056 80 GAPNCRQGLKVAVATIGAILPGDFKIKAAKLRGEPSEGMLCSFSELGISDDHSGIIELPADAPLGTDIREYLKLDDNTIE 159
Cdd:TIGR00472 81 GAPNVEAGKKVAVALPGAKLPNGLKIKKSKLRGVESEGMLCSESELGLDEKSDGIIVLDEDAPLGTDIAEYLGLDDDIIE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446595056 160 ISVTPNRADCLGIIGVARDVAVLNKAPLQEP--EMAPVTATISDTLPITVEAADACPRYLGRVVKGINVNaPTPLWMKEK 237
Cdd:TIGR00472 161 VSITPNRGDCLSILGIARELAALFDLNLETPvpFEPETTETIDEGFKIEIEDPEVCPFYLGRVIKGVKVK-PSPLWLKER 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446595056 238 LRRCGIRSIDAVVDVTNYVLLELGQPMHAFDKDRIDGGIVVRMAKEGETVVLLDGSEATLNADTLVIADHHKALGIAGIF 317
Cdd:TIGR00472 240 LRRSGIRPINNIVDITNYVMLELGQPLHAFDADKIEGNIVVRSAKEGESFTTLDGKERELKKGDLVIADDKKPLAIAGVM 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446595056 318 GGEHSGVNGETQNVLLECAYFNPLSITGRARRHGLHTDASHRYERGVDPALQYKAIERATRLLLDICGGDAGPIIdVSNE 397
Cdd:TIGR00472 320 GGKESGVTDTTTNIFLESAYFNPESIRKTARRLGISTDSSYRFERGVDPELTELALDRALNLILEIFGGEVISVV-SDNY 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446595056 398 ATLPKRATITLRRSKLDRLIGHHIADEQVSDILRRLGCEVTEGQDEWKAVAPTWRFDMEIEEDLVEEVARVYGYNNIPDE 477
Cdd:TIGR00472 399 KEKAKEKKISLRIKKLNKILGIELSDEEVRDILKRLGFKVEKQKDGWEVTVPSYRHDIEIEEDLIEEIARIYGYDNIPAE 478
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446595056 478 PIQAGLIMGTHREADLSLKRVKTMLNDKGYQEVITYSFVDP-KVQQLIHPGAEALL-LPNPISVEMSAMRLSLWSGLLAT 555
Cdd:TIGR00472 479 PLSVSSKLNKNNENYLLLRKLRTLLVGLGLNEVITYSFVDPeKAEKFNFPKLENLVeIKNPLSNERSVLRTSLLPSLLEV 558
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446595056 556 VVYNQNRQQNRVRIFETGLRFVPDtqaNLGIRQDLMLAGVICGNRYDEHWNLAKETVDFYDLKGDLEAVLDLTGKLGDIQ 635
Cdd:TIGR00472 559 LAYNQNRKNKDVKIFEIGKVFAKD---GEAVKEQLRLAILISGEKNPSSWNHKEEKVDFYDLKGDVESLLELLGLSDDVY 635
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446595056 636 FK-AEMNPALHPGQSAAIYLKDERIGFIGVVHPELERKLDLNGRTLVFELEWNKLADRI--VPQAREISRFPANRRDIAV 712
Cdd:TIGR00472 636 FKnTAENEELHPGQSATIYLKGKKIGFIGELHPEIAKKYDLKEPTFVFELDLDRLLESLkkVPKYRPISKFPAVTRDISF 715
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446595056 713 VVAENVPAADILSECKKVGVNQVVGVNLFDVYRGKGVAEGYKSLAISLILQDTNRTLEEEEIAATVAKCVEALKERFQAS 792
Cdd:TIGR00472 716 LVPKDVPANEIIKLIKKSGLELLEEVELFDVYQGKNIGEGKKSLALRLVLRDKERTLTDEEINKIVEKVLNALKEKLGAE 795
|
..
gi 446595056 793 LR 794
Cdd:TIGR00472 796 LR 797
|
|
| EMAP |
COG0073 |
tRNA-binding EMAP/Myf domain [Translation, ribosomal structure and biogenesis]; |
1-774 |
5.64e-171 |
|
tRNA-binding EMAP/Myf domain [Translation, ribosomal structure and biogenesis];
Pssm-ID: 439843 [Multi-domain] Cd Length: 773 Bit Score: 512.09 E-value: 5.64e-171
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446595056 1 MKFSELWLREWVNPAIDSDALANQITMAGLEVDGVEPVAGsFNGVVVGEVVECAQHPNADKLRVTKVNVGGErLLDIVCG 80
Cdd:COG0073 1 MKVSLSWLKEYVDLDLSPEELAEKLTMAGIEVEDFEKVGG-LDGLRVGKVLEAEPHPNADKLLVLQVDVGEE-TRQIVCG 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446595056 81 APNCRQGLKVAVATIGAILPGDFKIKAAKLRGEPSEGMLCSFSELGISDDHSGIIELPADAPLGTDIREYLKLDDNTIEI 160
Cdd:COG0073 79 APNVYAGDKVPEALVGAQVPGVVNLKPRKIRGVESEGMLCSAEELGLGEDHDGILELPEDAPPGDDAEYLLLLDDVIIEI 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446595056 161 SVTPNRADCLGIIGVARDVAVLNKAPLQEPEMAPVTATISDTLPITVEAADACPRYLGRVVKGINVNAPTPLWMKEKLRR 240
Cdd:COG0073 159 LTTPNRDDLLSVGGAAREAAALGGLLLKPPAPPVVEGTDDAVLVVVVDDDACDRYYGRVVRGVVNVVVPPPPWLRRLLRR 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446595056 241 CGIRSIDAVVDVTNYVLLELGQPMHAFDKDRIDGGIVVRMAKEGETVVLLDGSEATLNADTLVIADHHKALGIAGIFGGE 320
Cdd:COG0073 239 GGRRRIINVVDINNVVLLLLGQPHHAFDDDDLGGGIVVRRRRAEELLLLLLGDTTLLLDDLLLIDDDDDALAAAGGGGGG 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446595056 321 HSGVNGETQNVLLECAYFNPlSITGRARRHGLHTDASHRYERGVDPALQYKAIERATRLLLDICGGDAGPI-IDVSNEAT 399
Cdd:COG0073 319 GGSSGSTTTTTLLLAAAAFF-AAAGRRRRRRRLSSRSSRRRRREDDDDPRVAAAAAAAALLLIILGGGGGVaGGVVDEGL 397
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446595056 400 LPKRATITLRRSKLDRLIGHHIADEQVSDILRRLGCEVTEGQDEWKAVAPTWRFDMEIEEDLVEEVARVYGYNNIPDEPI 479
Cdd:COG0073 398 PPPPPRIIRLRRRRRLLLLGIDIDEEELLLLLLLLGFEVEGEGESVVVPPPRRRDDVIEEDEEEEEARRYYYYDLPPPPP 477
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446595056 480 QAGLIMGTHREADLSLKRVKTMLNDKGYQEVITYSFVDPKVQQLIHPGAEALLLPNPISVEMSAMRLSLWSGLLATVVYN 559
Cdd:COG0073 478 PAPPAVPEPPAARRRLRRRRRLLLLLGLEEAVTYSSFSELLLALLLLFEAALLLLLPPSSLSSSLLLSLLLLLLLLVLLL 557
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446595056 560 QNRQQNRVRIFETGLRFVPDTQANLGIRQDLMLAGVICGNRYDEHWNLAKETVDFYDLKGDLEAVLDLTGKLGDIQFKAE 639
Cdd:COG0073 558 LRRRNRNRRLFEGGEVFFGFEGGGLELLLAELEAGGALLLGGGGGAALGLAADDADDLAGVLLLLALLLGLLALLALAAA 637
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446595056 640 MNPALHPGQSAAIYLKDERIGFIGVVHPELERKLDLNGRTLVFELEWNKLADRIVPQAREISRFPANRRDIAVVVAENVP 719
Cdd:COG0073 638 APAAAAPGAGGAGGLLLGGGGGLGGLLPVLLKLLLLLLLALLFEVLLDELLLPAAVLLALPLVARPLLRAIVVDVAAAVA 717
|
730 740 750 760 770
....*....|....*....|....*....|....*....|....*....|....*
gi 446595056 720 AADILSECKKVGVNQVVGVNLFDVYRGKGVAEGYKSLAISLILQDTNRTLEEEEI 774
Cdd:COG0073 718 AALAAVAAALALVVALLAVVLLVVVVDVGVGKVLKKLLLSLDLEVTLLDLEELEL 772
|
|
| B3_4 |
pfam03483 |
B3/4 domain; This domain is found in tRNA synthetase beta subunits as well as in some non tRNA ... |
212-385 |
3.18e-97 |
|
B3/4 domain; This domain is found in tRNA synthetase beta subunits as well as in some non tRNA synthetase proteins.
Pssm-ID: 427327 [Multi-domain] Cd Length: 174 Bit Score: 299.46 E-value: 3.18e-97
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446595056 212 ACPRYLGRVVKGINVNAPTPLWMKEKLRRCGIRSIDAVVDVTNYVLLELGQPMHAFDKDRIDGGIVVRMAKEGETVVLLD 291
Cdd:pfam03483 1 ACPRYFGRVIRGVKKNRPSPEWLQRRLRRAGIRPINNVVDITNYVMLELGQPLHAFDLDKIAGDIVVRLAKGGEKFTTLD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446595056 292 GSEATLNADTLVIADHHKALGIAGIFGGEHSGVNGETQNVLLECAYFNPLSITGRARRHGLHTDASHRYERGVDPALQYK 371
Cdd:pfam03483 81 GKERELDPGDLVIADDDGPVALAGIMGGEESEVTEDTTNIFLESAGFDPVAIRKTARRLGLRTDASYRFERGVDPELVEA 160
|
170
....*....|....
gi 446595056 372 AIERATRLLLDICG 385
Cdd:pfam03483 161 ALDRATALLLELCG 174
|
|
| B3_4 |
smart00873 |
B3/4 domain; This domain is found in tRNA synthetase beta subunits as well as in some non tRNA ... |
213-385 |
2.03e-78 |
|
B3/4 domain; This domain is found in tRNA synthetase beta subunits as well as in some non tRNA synthetase proteins.
Pssm-ID: 214876 [Multi-domain] Cd Length: 174 Bit Score: 249.87 E-value: 2.03e-78
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446595056 213 CPRYLGRVVKGINVNAPTPLWMKEKLRRCGIRSIDAVVDVTNYVLLELGQPMHAFDKDRIDGG-IVVRMAKEGETVVLLD 291
Cdd:smart00873 1 CPRYLGRVIRGVKNTRPSPEWLQERLHRAGIRPINNVVDITNYVSLETGQPLHAFDLDKIKGKdIPLRRAKEGEKFETLD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446595056 292 GSEATLNADTLVIADHHKALGIAGIFGGEHSGVNGETQNVLLECAYFNPLSITGRARRHGLHTDASHRYERGVDPALQYK 371
Cdd:smart00873 81 GKEYELDEGDLVIADDEGPLALAGVMGGEESEVTENTTVIFLEPAIFSPRTIRITARTLNLFTDASGRFERGVDPELVEL 160
|
170
....*....|....
gi 446595056 372 AIERATRLLLDICG 385
Cdd:smart00873 161 ALDRAAALLLEICG 174
|
|
| PheRS_beta_core |
cd00769 |
Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II ... |
495-689 |
5.96e-74 |
|
Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA, PheRS is an exception in that it attaches the amino acid at the 2'-OH group, like class I aaRSs. PheRS is an alpha-2/ beta-2 tetramer. While the alpha chain contains a catalytic core domain, the beta chain has a non-catalytic core domain.
Pssm-ID: 238392 [Multi-domain] Cd Length: 198 Bit Score: 239.08 E-value: 5.96e-74
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446595056 495 LKRVKTMLNDKGYQEVITYSFVDPKVQQLI-HPGAEALLLPNPISVEMSAMRLSLWSGLLATVVYNQNRQQNRVRIFETG 573
Cdd:cd00769 6 ERKLRRLLAGLGFQEVITYSLTSPEEAELFdGGLDEAVELSNPLSEEYSVLRTSLLPGLLDALARNLNRKNKPLRLFEIG 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446595056 574 LRFVPDtqaNLGIRQDLMLAGVICGNRYDEHWNLAKETVDFYDLKGDLEAVLDLTGKLGDIQFKAEMNPALHPGQSAAIY 653
Cdd:cd00769 86 RVFLKD---EDGPEEEEHLAALLSGNREPESWQGKGRPVDFYDAKGILEALLRALGIIVEFELEELDADLFHPGRSAKIY 162
|
170 180 190
....*....|....*....|....*....|....*.
gi 446595056 654 LKDERIGFIGVVHPELERKLDLNGRTLVFELEWNKL 689
Cdd:cd00769 163 VNGEVIGFIGELHPEVLKEFDLKEPVYAFELDLDAL 198
|
|
| tRNA_synthFbeta |
pfam17759 |
Phenylalanyl tRNA synthetase beta chain CLM domain; This domain corresponds to the catalytic ... |
474-686 |
1.64e-73 |
|
Phenylalanyl tRNA synthetase beta chain CLM domain; This domain corresponds to the catalytic like domain (CLM) in the beta chain of phe tRNA synthetase.
Pssm-ID: 465487 [Multi-domain] Cd Length: 214 Bit Score: 238.60 E-value: 1.64e-73
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446595056 474 IPDEPIQAGLIMGTHREADLSLKRVKTMLNDKGYQEVITYSFVDPKVQQLI---HPGAEALLLPNPISVEMSAMRLSLWS 550
Cdd:pfam17759 1 IPSTLPKGPTTGGGLTPEQKLRRRVRDLLAAAGFTEVITYSFTSPKDLDKLledDPRRKAVKLANPLSEELSVMRTSLLP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446595056 551 GLLATVVYNQNRQQNRVRIFETGLRFVPDTQANLgIRQDLMLAGVICGNRYDEHWNLAKETVDFYDLKGDLEAVLDLTGk 630
Cdd:pfam17759 81 GLLETLAYNLNRGNPDVRLFEIGRVFLPDELEEL-PREPRRLAGLLTGKRLPESWQGKARPVDFYDLKGIVEALLAALG- 158
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 446595056 631 LGDIQFKAEMNPALHPGQSAAIYLKDERIGFIGVVHPELERKLDLNGRTLVFELEW 686
Cdd:pfam17759 159 IDDYEFEAADHPALHPGRSAEILVGGKVIGFIGELHPEVAKNFDLPQPVYVFELDL 214
|
|
| syfB |
CHL00192 |
phenylalanyl-tRNA synthetase beta chain; Provisional |
154-794 |
1.39e-66 |
|
phenylalanyl-tRNA synthetase beta chain; Provisional
Pssm-ID: 214391 [Multi-domain] Cd Length: 704 Bit Score: 234.60 E-value: 1.39e-66
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446595056 154 DDNTIEISVTPNRADCLGIIGVARDVAVL-NKAPLQEPEMAPvTATISD---TLPITVEAADACPRYLGRVVKGInVNAP 229
Cdd:CHL00192 45 SDIILDISSTANRSDVLSIQGLSREISALfNSDPIKLKYYNP-SISWFDklkNLISNDSSKLNCSMFIAVIIENI-EIKD 122
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446595056 230 TPLWMKEKLRRCGIRSIDAVVDVTNYVLLELGQPMHAFDKDRIDG-------GIVVRMAKEGETVVLLDGSEATLNADTL 302
Cdd:CHL00192 123 SPKWLQNRLSSSGFKSLNNLTDIQNYIMLETGQPIEIYDLDKIYSknttsslALSSKFALQKSSFIASNSKNIELENNIL 202
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446595056 303 VIADHHKALGIAGIFGGEHSGVNGETQNVLLECAYFNPLSITGRARRHGLHTDASHRYERGVDPALQYKAIERATRLLld 382
Cdd:CHL00192 203 VVQANNVIISIAGIISNEEIICDKNTKSILIEASIFDAAVIRKSSRKLGLRTDRSIRYEKSLKNDNLLEAYYRLVSLL-- 280
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446595056 383 icgGDAGPiiDVSNEATLPKRAT------ITLRRSKLDRLIG--------HHIADEQVSDILRRLGCEVTEGQDE--WKA 446
Cdd:CHL00192 281 ---RILNP--KLKCKFHFIYKKIknssrrIKLSYKKIKDILGpikintntRYLSPKEITNALKRLNFKITYDSLKlnWEV 355
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446595056 447 VAPTWR-FDMEIEEDLVEEVARVYGYNN----IPDepIQAGLIMGTHREadlSLKRVKTMLNDKGYQEVITYSFVDpkvQ 521
Cdd:CHL00192 356 LIPSYRkDDIVREIDVIEEIARIYGFNNflskLPN--IKFIGRLDIDYN---TRDKIRSYLRNLGLTELIHYSLVK---Q 427
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446595056 522 QLIHPGAEALLlpNPISVEMSAMRLSLWSGLLATVVYNQNRQQNRVRIFETGLRFVPDTQanlGIRQDLMLAGVICGN-R 600
Cdd:CHL00192 428 ESFSKNEIKLK--NPLIKDYSTLRSSLLPGLIEAVQENLKQGNSTLEGFEIGHVFNLDSS---SIIEETELAGGIFGGiD 502
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446595056 601 YDEHWNLAKETVDFYDLKGDLEAVLDLTGKLGDIQFKAEMNPA--LHPGQSAAIYLKD-ERIGFIGVVHPELERKLDLNG 677
Cdd:CHL00192 503 IRSSWSEKAQSLNWFEAKGIIENFFQKLNLPIYWKKYSDLDEKinFHPYCTSEIFLSNgQKIGIFGQLHPLLANKLNLNT 582
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446595056 678 RTLVFELEWNKLADRIvPQAREI-----SRFPANRRDIAVVVAENVPAADILSECKKVGVNQVVGVNLFDVYRGKGVAEG 752
Cdd:CHL00192 583 EIYLFEINLDILQYSI-QQNNLIsyqpySSYPKIIRDLSFIIKKSISISKIKELIYQNGDNLLESITLFDYYKGKSIPNG 661
|
650 660 670 680
....*....|....*....|....*....|....*....|..
gi 446595056 753 YKSLAISLILQDTNRTLEEEEIAATVAKCVEALKERFQASLR 794
Cdd:CHL00192 662 HTSLGLRLTFQSENKTLTNEEIDRIQQNLQKVLEKKLNAEIR 703
|
|
| tRNA_bind_bactPheRS |
cd02796 |
tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain. ... |
53-147 |
9.79e-49 |
|
tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain. PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate the 2'OH of the terminal ribose of tRNA they belong functionally to class 1 aaRSs. This domain has general tRNA binding properties and is believed to direct tRNAphe to the active site of the enzyme.
Pssm-ID: 239196 [Multi-domain] Cd Length: 103 Bit Score: 166.91 E-value: 9.79e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446595056 53 CAQHPNADKLRVTKVNVGGERLLDIVCGAPNCRQGLKVAVATIGAILPGDFKIKAAKLRGEPSEGMLCSFSELGISDDHS 132
Cdd:cd02796 9 VEPHPNADKLNVCKVDIGENKPLQIVCGAPNVRAGDKVVVALPGAVLPGGLKIKKRKLRGVESEGMLCSAKELGLGEDSD 88
|
90
....*....|....*
gi 446595056 133 GIIELPADAPLGTDI 147
Cdd:cd02796 89 GIIELPEDAPVGTDI 103
|
|
| FDX-ACB |
smart00896 |
Ferredoxin-fold anticodon binding domain; This is the anticodon binding domain found in some ... |
701-794 |
1.13e-33 |
|
Ferredoxin-fold anticodon binding domain; This is the anticodon binding domain found in some phenylalanyl tRNA synthetases. The domain has a ferredoxin fold, consisting of an alpha+beta sandwich with anti-parallel beta-sheets (beta-alpha-beta x2).
Pssm-ID: 214893 [Multi-domain] Cd Length: 93 Bit Score: 124.07 E-value: 1.13e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446595056 701 SRFPANRRDIAVVVAENVPAADILSECKKVGVNQVVGVNLFDVYRGkGVAEGYKSLAISLILQDTNRTLEEEEIAATVAK 780
Cdd:smart00896 1 SKFPAVRRDLAFVVDEDVPAAELLDAIREAGGDLLEDVRLFDVYEG-GIPEGKKSLAYRLTYQSPDRTLTDEEVNAIHDK 79
|
90
....*....|....
gi 446595056 781 CVEALKERFQASLR 794
Cdd:smart00896 80 IVAALEKKFGAELR 93
|
|
| FDX-ACB |
pfam03147 |
Ferredoxin-fold anticodon binding domain; This is the anticodon binding domain found in some ... |
701-794 |
1.39e-33 |
|
Ferredoxin-fold anticodon binding domain; This is the anticodon binding domain found in some phenylalanyl tRNA synthetases. The domain has a ferredoxin fold.
Pssm-ID: 460826 [Multi-domain] Cd Length: 94 Bit Score: 124.13 E-value: 1.39e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446595056 701 SRFPANRRDIAVVVAENVPAADILSECKKVGVNQVVGVNLFDVYRGKGVAEGYKSLAISLILQDTNRTLEEEEIAATVAK 780
Cdd:pfam03147 1 SKYPAVRRDLAFVVDEDVPAADILKAIREAGGELLESVELFDVYRGEKIPEGKKSLAFRLTFQSPERTLTDEEVNAIIEK 80
|
90
....*....|....
gi 446595056 781 CVEALKERFQASLR 794
Cdd:pfam03147 81 IVEALEKKFGAELR 94
|
|
| tRNA_bindingDomain |
cd02153 |
The tRNA binding domain is also known as the Myf domain in literature. This domain is found in ... |
53-147 |
4.73e-30 |
|
The tRNA binding domain is also known as the Myf domain in literature. This domain is found in a diverse collection of tRNA binding proteins, including prokaryotic phenylalanyl tRNA synthetases (PheRS), methionyl-tRNA synthetases (MetRS), human tyrosyl-tRNA synthetase(hTyrRS), Saccharomyces cerevisiae Arc1p, Thermus thermophilus CsaA, Aquifex aeolicus Trbp111, human p43 and human EMAP-II. PheRS, MetRS and hTyrRS aminoacylate their cognate tRNAs. Arc1p is a transactivator of yeast methionyl-tRNA and glutamyl-tRNA synthetases. The molecular chaperones Trbp111 and CsaA also contain this domain. CsaA has export related activities; Trbp111 is structure-specific recognizing the L-shape of the tRNA fold. This domain has general tRNA binding properties. In a subset of this family this domain has the added capability of a cytokine. For example the p43 component of the Human aminoacyl-tRNA synthetase complex is cleaved to release EMAP-II cytokine. EMAP-II has multiple activities during apoptosis, angiogenesis and inflammation and participates in malignant transformation. An EMAP-II-like cytokine is released from hTyrRS upon cleavage. The active cytokine heptapeptide locates to this domain. For homodimeric members of this group which include CsaA, Trbp111 and Escherichia coli MetRS this domain acts as a dimerization domain.
Pssm-ID: 239066 [Multi-domain] Cd Length: 99 Bit Score: 114.15 E-value: 4.73e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446595056 53 CAQHPNADKLRVTKVNVGGERLLDIVCGAPNC-----RQGLKVAVATIgailpgdfkIKAAKLRGEPSEGMLCSFSELGI 127
Cdd:cd02153 9 AEPHPNADKLYVLKVDIGEEKPRQIVSGAANVyppeeLVGKKVVVAVN---------LKPKKLRGVESEGMLLSAEELGL 79
|
90 100
....*....|....*....|
gi 446595056 128 SDDHSGIIELPADAPLGTDI 147
Cdd:cd02153 80 EEGSVGILELPEDAPVGDRI 99
|
|
| B5 |
smart00874 |
tRNA synthetase B5 domain; This domain is found in phenylalanine-tRNA synthetase beta subunits. |
404-471 |
8.20e-28 |
|
tRNA synthetase B5 domain; This domain is found in phenylalanine-tRNA synthetase beta subunits.
Pssm-ID: 197942 [Multi-domain] Cd Length: 68 Bit Score: 106.43 E-value: 8.20e-28
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446595056 404 ATITLRRSKLDRLIGHHIADEQVSDILRRLGCEVTEGQDEWKAVAPTWRFDMEIEEDLVEEVARVYGY 471
Cdd:smart00874 1 RTITLRLERINRLLGLEILAEEIEEILKRLGFEVEVSGDTLEVTVPSYRFDILIEADLIEEVARIYGY 68
|
|
| tRNA_bind |
pfam01588 |
Putative tRNA binding domain; This domain is found in prokaryotic methionyl-tRNA synthetases, ... |
53-146 |
1.00e-25 |
|
Putative tRNA binding domain; This domain is found in prokaryotic methionyl-tRNA synthetases, prokaryotic phenylalanyl tRNA synthetases the yeast GU4 nucleic-binding protein (G4p1 or p42, ARC1), human tyrosyl-tRNA synthetase, and endothelial-monocyte activating polypeptide II. G4p1 binds specifically to tRNA form a complex with methionyl-tRNA synthetases. In human tyrosyl-tRNA synthetase this domain may direct tRNA to the active site of the enzyme. This domain may perform a common function in tRNA aminoacylation.
Pssm-ID: 396251 [Multi-domain] Cd Length: 96 Bit Score: 101.55 E-value: 1.00e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446595056 53 CAQHPNADKLRVTKVNVGGERLLDIVCGAPNCRQGLKVaVATIGAILPgdfKIKAAKLRGEPSEGMLCSFSELgiSDDHS 132
Cdd:pfam01588 9 AERHPNADKLLVCKVDVGEEEPRQIVSGAVNVYPPEEL-VGRLVVVVA---NLKPAKLRGVESEGMILSAEEL--DGGSV 82
|
90
....*....|....
gi 446595056 133 GIIELPADAPLGTD 146
Cdd:pfam01588 83 GLLEPPADVPPGTK 96
|
|
| B5 |
pfam03484 |
tRNA synthetase B5 domain; This domain is found in phenylalanine-tRNA synthetase beta subunits. |
406-471 |
2.44e-24 |
|
tRNA synthetase B5 domain; This domain is found in phenylalanine-tRNA synthetase beta subunits.
Pssm-ID: 460942 [Multi-domain] Cd Length: 67 Bit Score: 96.69 E-value: 2.44e-24
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446595056 406 ITLRRSKLDRLIGHHIADEQVSDILRRLGCEVTE-GQDEWKAVAPTWRFDMEIEEDLVEEVARVYGY 471
Cdd:pfam03484 1 ITLRLDRINRLLGIDLSAEEIVEILERLGFEVEEeDGDTLTVTVPSYRPDILHEADLIEEVARIYGY 67
|
|
| PLN02265 |
PLN02265 |
probable phenylalanyl-tRNA synthetase beta chain |
415-685 |
8.30e-18 |
|
probable phenylalanyl-tRNA synthetase beta chain
Pssm-ID: 215149 [Multi-domain] Cd Length: 597 Bit Score: 87.81 E-value: 8.30e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446595056 415 RLIGHHIADEQVSDILRR--LGCEVT-EGQDEWKAVAPTWRFDMEIEEDLVEEVARVYGYNNIPDEPIQAGLIMGTHREA 491
Cdd:PLN02265 321 SSIGVSLDAEEVASLLNKmqLQAEQSsDDGCTIRVSVPPTRSDILHPCDVAEDVAIAYGYNNIPKRKPKSMTVGKQQPLN 400
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446595056 492 DLS-LKRVKTMLNdkGYQEVITYSFV--DPKVQQLIHP--GAEALLLPNPISVEMSAMRLSLWSGLLATVVYNQNRQQNr 566
Cdd:PLN02265 401 QFSdLLRAEVAMA--GFTEVLTWILCshKENFAMLNREddGNSAVIIGNPRSADFEVVRTSLLPGLLKTLGHNKDAPKP- 477
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446595056 567 VRIFETGLRFVPDTQANLGIRQDLMLAGVICGnrydehwnlakETVDFYDLKGDLEAVLDLTG----KLGDI---QFKAE 639
Cdd:PLN02265 478 IKLFEVSDVVLLDESKDVGARNSRRLAALYCG-----------TTSGFEVIHGLVDRIMEVLGipfvEIGDNngyYVEPS 546
|
250 260 270 280
....*....|....*....|....*....|....*....|....*.
gi 446595056 640 MNPALHPGQSAAIYLKDERIGFIGVVHPELERKLDLNGRTLVFELE 685
Cdd:PLN02265 547 NEPEYFPGRQASIIYKGKHVGTFGIVHPEVLNNFDIPDPCSFLELD 592
|
|
| B3/B4 |
COG3382 |
B3/B4 domain (DNA/RNA-binding domain of Phe-tRNA-synthetase) [General function prediction only] ... |
238-399 |
2.87e-10 |
|
B3/B4 domain (DNA/RNA-binding domain of Phe-tRNA-synthetase) [General function prediction only];
Pssm-ID: 442609 [Multi-domain] Cd Length: 233 Bit Score: 61.02 E-value: 2.87e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446595056 238 LRRCGIRSIDAVVDVTNYVLLELGQPMHAFDKDRIDGGIVVRMAKEGETVVLLDGSEATLNADTLVI-ADhhkalgIAGI 316
Cdd:COG3382 90 LKGGGLPRINPLVDLYNAVSLRYLLPIGGYDLDKIEGDLRLRLARGGESFLPIGGDEEEPPEPGEVVyAD------DEGV 163
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446595056 317 FG-------GEHSGVNGETQNVLLeCAYFNPlsitgrarrhglhtdashryerGVDPALQYKAIERATRLLLDICGGDA- 388
Cdd:COG3382 164 FCrrwpwrdSERTKVTEETKNALF-IIEGLP----------------------GVSAEDLEAALDELAELLERYLGGEVv 220
|
170
....*....|..
gi 446595056 389 -GPIIDVSNEAT 399
Cdd:COG3382 221 kTRILDADNPEF 232
|
|
| tRNA_bind_EMAP-II_like |
cd02799 |
tRNA-binding-domain-containing EMAP2-like proteins. This family contains a diverse fraction of ... |
53-147 |
8.27e-09 |
|
tRNA-binding-domain-containing EMAP2-like proteins. This family contains a diverse fraction of tRNA binding proteins, including Caenorhabditis elegans methionyl-tRNA synthetase (CeMetRS), human tyrosyl- tRNA synthetase (hTyrRS), Saccharomyces cerevisiae Arc1p, human p43 and EMAP2. CeMetRS and hTyrRS aminoacylate their cognate tRNAs. Arc1p is a transactivator of yeast methionyl-tRNA and glutamyl-tRNA synthetases. This domain has general tRNA binding properties. In a subset of this family this domain has the added capability of a cytokine. For example the p43 component of the Human aminoacyl-tRNA synthetase complex is cleaved to release EMAP-II cytokine. EMAP-II has multiple activities during apoptosis, angiogenesis and inflammation and participates in malignant transformation. A EMAP-II-like cytokine also is released from hTyrRS upon cleavage. The active cytokine heptapeptide locates to this domain.
Pssm-ID: 239198 [Multi-domain] Cd Length: 105 Bit Score: 53.77 E-value: 8.27e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446595056 53 CAQHPNADKLRVTKVNVGGERLLDIVCG-----APNCRQGLKVAVATigailpgdfKIKAAKLRGEPSEGM-LCsfselG 126
Cdd:cd02799 16 VRKHPDADSLYVEEIDLGEEEPRTIVSGlvkfvPLEQMQNRLVVVLC---------NLKPRKMRGVKSQGMvLC-----A 81
|
90 100
....*....|....*....|...
gi 446595056 127 ISDDHSG--IIELPADAPLGTDI 147
Cdd:cd02799 82 SNADHEKveLLEPPEGAKPGERV 104
|
|
| PRK12267 |
PRK12267 |
methionyl-tRNA synthetase; Reviewed |
53-148 |
2.15e-04 |
|
methionyl-tRNA synthetase; Reviewed
Pssm-ID: 237028 [Multi-domain] Cd Length: 648 Bit Score: 44.79 E-value: 2.15e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446595056 53 CAQHPNADKLRVTKVNVGGERLLDIVCG-----APNCRQGLKVAVATigailpgdfKIKAAKLRGEPSEGMLCSFSElgi 127
Cdd:PRK12267 561 AEKVEKSDKLLKLQVDLGEEEPRQIVSGiakfyPPEELVGKKVVVVA---------NLKPAKLMGEESQGMILAAED--- 628
|
90 100
....*....|....*....|.
gi 446595056 128 sDDHSGIIELPADAPLGTDIR 148
Cdd:PRK12267 629 -DGKLTLLTVDKEVPNGSKVK 648
|
|
| |
