|
Name |
Accession |
Description |
Interval |
E-value |
| PRK10614 |
PRK10614 |
multidrug efflux system subunit MdtC; Provisional |
1-1025 |
0e+00 |
|
multidrug efflux system subunit MdtC; Provisional
Pssm-ID: 182589 [Multi-domain] Cd Length: 1025 Bit Score: 2055.84 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 1 MKFFALFIYRPVATILLSVAITLCGILGFRMLPVAPLPQVDFPVIMVSASLPGASPETMASSVATPLERSLGRIAGVSEM 80
Cdd:PRK10614 1 MKFFALFIYRPVATILLSLAITLCGILGFRLLPVAPLPQVDFPVIMVSASLPGASPETMASSVATPLERSLGRIAGVNEM 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 81 TSSSSLGSTRIILQFDFDRDINGAARDVQAAINAAQSLLPSGMPSRPTYRKANPSDAPIMILTLTSDTYSQGELYDFAST 160
Cdd:PRK10614 81 TSSSSLGSTRIILQFDFDRDINGAARDVQAAINAAQSLLPSGMPSRPTYRKANPSDAPIMILTLTSDTYSQGQLYDFAST 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 161 QLAPTISQIDGVGDVDVGGSSLPAVRVGLNPQALFNQGVSLDDVRSAISNANVRKPQGALEDSTHRWQIQTNDELKTAAE 240
Cdd:PRK10614 161 QLAQTISQIDGVGDVDVGGSSLPAVRVGLNPQALFNQGVSLDDVRQAISNANVRRPQGAVEDGTHRWQIQTNDELKTAAE 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 241 YQPLIIHYNNGGAVRLGDVATVTDSVQDVRNAGMTNAKPAILLMIRKLPEANIIQTVDSIRAKLPELQETIPAAIDLQIA 320
Cdd:PRK10614 241 YQPLIIHYNNGAAVRLGDVATVTDSVQDVRNAGMTNAKPAILLMIRKLPEANIIQTVDRIRAKLPELRETIPAAIDLQIA 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 321 QDRSPTIRASLEEVEQTLIISVALVILVVFLFLRSGRATIIPAVAVPVSLIGTFAAMYLCGFSLNNLSLMALTIATGFVV 400
Cdd:PRK10614 321 QDRSPTIRASLEEVEQTLAISVALVILVVFLFLRSGRATLIPAVAVPVSLIGTFAAMYLCGFSLNNLSLMALTIATGFVV 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 401 DDAIVVLENIARHLEAGMKPLQAALQGTREVGFTVLSMSLSLVAVFLPLLLMGGLPGRLLREFAVTLSVAIGISLLVSLT 480
Cdd:PRK10614 401 DDAIVVLENISRHLEAGMKPLQAALQGVREVGFTVLSMSLSLVAVFLPLLLMGGLPGRLFREFAVTLSVAIGISLLVSLT 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 481 LTPMMCGWMLKASKPREQKRLRGFGRMLVALQQGYGKSLKWVLNHTRLVGVVLLGTIALNIWLYISIPKTFFPEQDTGVL 560
Cdd:PRK10614 481 LTPMMCAWLLKSSKPREQKRLRGFGRMLVALQQGYGRSLKWVLNHTRWVGVVLLGTIALNVWLYISIPKTFFPEQDTGRL 560
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 561 MGGIQADQSISFQAMRGKLQDFMKIIRDDPAVDNVTGFTGGSRVNSGMMFITLKPRDERSETAQQIIDRLRVKLAKEPGA 640
Cdd:PRK10614 561 MGFIQADQSISFQAMRGKLQDFMKIIRDDPAVDNVTGFTGGSRVNSGMMFITLKPLSERSETAQQVIDRLRVKLAKEPGA 640
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 641 NLFLMAVQDIRVGGRQSNASYQYTLLSDDLAALREWEPKIRKKLATLPELADVNSDQQDNGAEMNLVYDRDTMARLGIDV 720
Cdd:PRK10614 641 NLFLMAVQDIRVGGRQSNASYQYTLLSDDLAALREWEPKIRKALAALPELADVNSDQQDKGAEMALTYDRDTMARLGIDV 720
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 721 QAANSLLNNAFGQRQISTIYQPMNQYKVVMEVDPRYTQDISALEKMFVINNEGKAIPLSYFAKWQPANAPLSVNHQGLSA 800
Cdd:PRK10614 721 QAANSLLNNAFGQRQISTIYQPLNQYKVVMEVDPRYTQDISALEKMFVINNEGKAIPLSYFAKWQPANAPLSVNHQGLSA 800
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 801 ASTISFNLPTGKSLSDASAAIDRAMTQLGVPSTVRGIFAGTAQVFQETMNSQVILIIAAIATVYIVLGILYESYVHPLTI 880
Cdd:PRK10614 801 ASTISFNLPTGKSLSDASAAIERAMTQLGVPSTVRGSFAGTAQVFQETMNSQLILILAAIATVYIVLGILYESYVHPLTI 880
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 881 LSTLPSAGVGALLALELFNAPFSLIALIGIMLLIGIVKKNAIMMVDFALEAQRHGNLTPQEAIFQACLLRFRPIMMTTLA 960
Cdd:PRK10614 881 LSTLPSAGVGALLALELFNAPFSLIALIGIMLLIGIVKKNAIMMVDFALEAQRNGNLTAQEAIFQACLLRFRPIMMTTLA 960
|
970 980 990 1000 1010 1020
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446590158 961 ALFGALPLVLSGGDGSELRQPLGITIVGGLVMSQLLTLYTTPVVYLFFDRLRLRFSRKPKQAVTE 1025
Cdd:PRK10614 961 ALFGALPLVLSGGDGAELRQPLGITIVGGLVMSQLLTLYTTPVVYLFFDRLRLRFSRKPKQTVTE 1025
|
|
| RND_permease_2 |
NF033617 |
multidrug efflux RND transporter permease subunit; |
4-1010 |
0e+00 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 411236 [Multi-domain] Cd Length: 1009 Bit Score: 1433.27 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 4 FALFIYRPVATILLSVAITLCGILGFRMLPVAPLPQVDFPVIMVSASLPGASPETMASSVATPLERSLGRIAGVSEMTSS 83
Cdd:NF033617 1 SDVFIKRPVATLLLSLLILLLGLLAFRKLPVREYPEVDFPTITVSTSYPGASPELMQSSITQPLEQQLAQIEGIDEMTSQ 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 84 SSLGSTRIILQFDFDRDINGAARDVQAAINAAQSLLPSGMPSRPTYRKANPSDAPIMILTLTSDTYSQGELYDFASTQLA 163
Cdd:NF033617 81 SSLGYSTITLQFRLGTDLDVALSEVQAAINAAQSLLPSEAPDPPVYRKANSADTPIMYIGLTSEEMPRGQLTDYAERVLA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 164 PTISQIDGVGDVDVGGSSLPAVRVGLNPQALFNQGVSLDDVRSAISNANVRKPQGALEDSTHRWQIQTNDELKTAAEYQP 243
Cdd:NF033617 161 PKLSQINGVGSVDVSGGQRPAMRVWLDPEKMAARGLTADDVRSALNSNNVNSPKGAVRGDSVVSTVRANDQLKTAEDYED 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 244 LIIHYN-NGGAVRLGDVATVTDSVQDVRNAGMTNAKPAILLMIRKLPEANIIQTVDSIRAKLPELQETIPAAIDLQIAQD 322
Cdd:NF033617 241 LVIKYAdNGAPVRLGDVATVELGAENVRNRAWANGVPAVVLGINRQPGANPIEVADEIRALLPELQETLPKNIKVNVLYD 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 323 RSPTIRASLEEVEQTLIISVALVILVVFLFLRSGRATIIPAVAVPVSLIGTFAAMYLCGFSLNNLSLMALTIATGFVVDD 402
Cdd:NF033617 321 RTRFIRASIDEVESTLLEAVALVILVVFLFLRNLRATLIPAVTVPLSLIGTFAVMYLFGFSINLLTLMALVLAIGLVVDD 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 403 AIVVLENIARHLEAGMKPLQAALQGTREVGFTVLSMSLSLVAVFLPLLLMGGLPGRLLREFAVTLSVAIGISLLVSLTLT 482
Cdd:NF033617 401 AIVVVENIHRHIEEGESPLEAALKGAREIGFTVIAMTLTLVAVYLPILFMGGLTGRLFREFAVTLAGAVIISGIVALTLT 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 483 PMMCGWMLKASkPREQKRLRGFGRMLVALQQGYGKSLKWVLNHTRLVGVVLLGTIALNIWLYISIPKTFFPEQDTGVLMG 562
Cdd:NF033617 481 PMMCSRLLKAN-EKPGRFARAVDRFFDGLTARYGRGLKWVLKHRPLTLVVALATLALLPLLYVFIPKELAPSEDRGVIFG 559
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 563 GIQADQSISFQAMRGKLQDFMKIIRDDPAVDNVTGFTGGSRVNS---GMMFITLKPRDERSETAQQIIDRLRVKLAKEPG 639
Cdd:NF033617 560 MIQAPQSISLDYMSAKMRDVEKILSSDPEVQSLTSFNGVGGNPGdntGFGIINLKPWDERDVSAQEIIDRLRPKLAKVPG 639
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 640 ANLFLMAVQDIRVGGRQSNASYQYTLLSDDLAALREWEPKIRKKLATLPELADVNSDQQDNGAEMNLVYDRDTMARLGID 719
Cdd:NF033617 640 MDLFLFPLQDLPGGAGSSLPQYQVTLTPSDYDSLFTWAEKLKEKLRKSPQFADVDSDLQDKGPELNVDIDRDKAARLGIS 719
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 720 VQAANSLLNNAFGQRQISTIYQPMNQYKVVMEVDPRYTQDISALEKMFVINNEGKAIPLSYFAKWQPANAPLSVNHQGLS 799
Cdd:NF033617 720 MQDIGSTLEVAFGQRQVNTIYTDGNQYKVVLEVDRRYRLNPEALNQIYVRSNDGKLVPLSTLAKIEERAAPLSLNHFNQF 799
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 800 AASTISFNLPTGKSLSDASAAIDRAMTQLgVPSTVRGIFAGTAQVFQETMNSQVILIIAAIATVYIVLGILYESYVHPLT 879
Cdd:NF033617 800 NSATLSFNLAPGVSLGEAIEALDQAAKEL-LPSGISGSFQGAARAFQEEGSSLLFLFLLALAAIYLVLAIQYESFVDPLT 878
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 880 ILSTLPSAGVGALLALELFNAPFSLIALIGIMLLIGIVKKNAIMMVDFALEAQRHGNLTPQEAIFQACLLRFRPIMMTTL 959
Cdd:NF033617 879 ILSTVPLAGCGALLALALGGQSMNIYAQIGLITLIGLVKKNGILMVEFANELQRHQGLSRREAIYQAAALRLRPILMTTL 958
|
970 980 990 1000 1010
....*....|....*....|....*....|....*....|....*....|.
gi 446590158 960 AALFGALPLVLSGGDGSELRQPLGITIVGGLVMSQLLTLYTTPVVYLFFDR 1010
Cdd:NF033617 959 AMLLGAIPLMLSTGAGAESRFPLGIVIVGGLGVGTLFTLFVLPVVYLLLAR 1009
|
|
| ACR_tran |
pfam00873 |
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are ... |
3-1009 |
0e+00 |
|
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer.
Pssm-ID: 395701 [Multi-domain] Cd Length: 1021 Bit Score: 1215.98 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 3 FFALFIYRPVATILLSVAITLCGILGFRMLPVAPLPQVDFPVIMVSASLPGASPETMASSVATPLERSLGRIAGVSEMTS 82
Cdd:pfam00873 1 MSKFFIRRPIFTLVLAIAILLAGILSFFSLPVDAFPEIAPPTVQVSTSYPGASPEEVEDTVTQPIEQAMNGLDGLKYMSS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 83 SSSLGSTRIILQFDFDRDINGAARDVQAAINAAQSLLPSGMpSRPTYRKANPSDAPIMILTLTSD--TYSQGELYDFAST 160
Cdd:pfam00873 81 QSSYGLSSITLTFELGTDIDIARQDVQNRLQLATPLLPEGV-QRPGISVIKTSLGPIMVLAVTSPdgSYTQTDLRDYADT 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 161 QLAPTISQIDGVGDVDVGGSSLPAVRVGLNPQALFNQGVSLDDVRSAISNANVRKPQGALEDSTHRWQIQTNDELKTAAE 240
Cdd:pfam00873 160 NIKPQLSRVPGVGDVQLFGGSEYAMRIWLDPQKLARYGLTLTDVVSALKEQNVNIGAGQLEGQGLQALIRAQGQLQSAED 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 241 YQPLIIHYNNGGAVRLGDVATVTDSVQDVRNAGMTNAKPAILLMIRKLPEANIIQTVDSIRAKLPELQETIPAAIDLQIA 320
Cdd:pfam00873 240 FEKIIVKNQDGSPVRLRDVATVELGSELYRGFATFNGKPAVGLGVQKLPGANAIETADAVRAKLAELKPTFPQGVEIVVV 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 321 QDRSPTIRASLEEVEQTLIISVALVILVVFLFLRSGRATIIPAVAVPVSLIGTFAAMYLCGFSLNNLSLMALTIATGFVV 400
Cdd:pfam00873 320 YDTTPFIRASIEEVVKTLLEAIVLVILVMFLFLQNWRATLIPAIAIPLSLLGTFAVMKAFGFSINTLTLGGLVLAIGLVV 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 401 DDAIVVLENIARHLEA-GMKPLQAALQGTREVGFTVLSMSLSLVAVFLPLLLMGGLPGRLLREFAVTLSVAIGISLLVSL 479
Cdd:pfam00873 400 DDAIVVVENIERVLEEnGLKPLEAAYKSMGEIGGALVAIALVLSAVFLPILFLGGLTGRIFRQFAITIVLAILLSVLVAL 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 480 TLTPMMCGWMLKASKPREQKRL-RGFGRMLVALQQGYGKSLKWVLNHTRLVGVVLLGTIALNIWLYISIPKTFFPEQDTG 558
Cdd:pfam00873 480 TLTPALCATLLKPRREPKHGGFfRWFNRMFDRLTRGYAKLLAKVLRHTAVVLLVALLLVVGSVWLFVRIPTEFLPEEDEG 559
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 559 VLMGGIQADQSISFQAMRGKLQDFMKIIRDDPAVDNVTGFTGGS------RVNSGMMFITLKPRDER---SETAQQIIDR 629
Cdd:pfam00873 560 VFVTSAQLPPGVSLDQTQRVMKQVEKILKEKPEVESVFAVTGFAfsgdnnGPNSGDAFISLKPWKERpgpEKSVQALIER 639
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 630 LRVKLAKEPGANLFLMAVQDIRV--GGRQSNASYQYTLLSDDLAALREWEPKIRKKLATLPELADVNSDQQDNGAEMNLV 707
Cdd:pfam00873 640 LRKALKQIPGANVFLFQPIQLRGlgTISGFRSDLQVKIFGDDLDALDEARNQILAALAQLPGLSDVRSDGQEDQPQLQVN 719
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 708 YDRDTMARLGIDVQAANSLLNNAFGQRQISTIYQPMNQYKVVMEVDPRYTQDISALEKMFVINNEGKAIPLSYFAKWQPA 787
Cdd:pfam00873 720 IDREKAARLGVSIQDINDTLSTALGGSYVNDFPEGGRVYDVVVQLPEDFRSSPEDIGQLYVRNPYGKMIPLSAFAKIEWG 799
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 788 NAPLSVNHQGLSAASTISFNLPTGKSLSDASAAIDRAMTQLGVPSTVRGIFAGTAQVFQETMNSQVILIIAAIATVYIVL 867
Cdd:pfam00873 800 YGPPSINRYNGFRSIVISGNVAAGDSLGDAMEAMAQIAKQVKLPPGYGYTWTGQFEQEQLAGNSLPILIALALLVVFLVL 879
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 868 GILYESYVHPLTILSTLPSAGVGALLALELFNAPFSLIALIGIMLLIGIVKKNAIMMVDFALEAQRHGNLTPQEAIFQAC 947
Cdd:pfam00873 880 AALYESWSDPLSIMLTVPLALVGALLALWLRGLPNSVYAQVGLILLIGLAVKNAILMVEFANELREQEGKSLEEAILEAC 959
|
970 980 990 1000 1010 1020
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446590158 948 LLRFRPIMMTTLAALFGALPLVLSGGDGSELRQPLGITIVGGLVMSQLLTLYTTPVVYLFFD 1009
Cdd:pfam00873 960 RLRLRPILMTALAAILGVLPLALSTGAGSELQQPLGIVVFGGLVTSTVLTLLVVPVFYVLFH 1021
|
|
| AcrB |
COG0841 |
Multidrug efflux pump subunit AcrB [Defense mechanisms]; |
1-1015 |
0e+00 |
|
Multidrug efflux pump subunit AcrB [Defense mechanisms];
Pssm-ID: 440603 [Multi-domain] Cd Length: 1015 Bit Score: 1159.86 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 1 MKFFALFIYRPVATILLSVAITLCGILGFRMLPVAPLPQVDFPVIMVSASLPGASPETMASSVATPLERSLGRIAGVSEM 80
Cdd:COG0841 1 MNLSRFFIRRPVAAIVLSLLILLAGLLAYLRLPVEQFPDIDPPTVTVSTTYPGASPEEVESTVTTPIEEALNGVEGIKYI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 81 TSSSSLGSTRIILQFDFDRDINGAARDVQAAINAAQSLLPSGMpSRPTYRKANPSDAPIMILTLTSDTYSQGELYDFAST 160
Cdd:COG0841 81 TSTSSEGSSSITVEFELGTDIDEALVDVQNAVDRARSDLPEDV-EPPGVTKVNPSDFPVMVLALSSDDLDELELSDYAER 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 161 QLAPTISQIDGVGDVDVGGSSLPAVRVGLNPQALFNQGVSLDDVRSAISNANVRKPQGALEDSTHRWQIQTNDELKTAAE 240
Cdd:COG0841 160 NIKDRLERVPGVGQVQIFGGREREIRIWLDPDKLAAYGLTLADVANAIRAQNVDVPAGRIGGGDREYTVRTNGRLKTPEE 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 241 YQPLIIHYNNGGAVRLGDVATVTDSVQDVRNAGMTNAKPAILLMIRKLPEANIIQTVDSIRAKLPELQETIPAAIDLQIA 320
Cdd:COG0841 240 FENIVIRTNDGSVVRLGDVARVEDGAEDYRSIARLNGKPAVGLAIQKQPGANALEVADAVRAKLEELQASLPEGVELTIV 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 321 QDRSPTIRASLEEVEQTLIISVALVILVVFLFLRSGRATIIPAVAVPVSLIGTFAAMYLCGFSLNNLSLMALTIATGFVV 400
Cdd:COG0841 320 YDQSEFIRASIEEVVKTLLEAILLVVLVVFLFLRSWRATLIPAVAIPVSLIGTFAVMYLLGFSLNILTLFALVLAIGIVV 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 401 DDAIVVLENIARHLEAGMKPLQAALQGTREVGFTVLSMSLSLVAVFLPLLLMGGLPGRLLREFAVTLSVAIGISLLVSLT 480
Cdd:COG0841 400 DDAIVVVENIERHMEEGLSPLEAAIKGAREVAGAVIASTLTLVAVFLPLAFMGGITGQLFRQFALTVAIALLISLFVALT 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 481 LTPMMCGWMLKASKPREQKRL-RGFGRMLVALQQGYGKSLKWVLNHTRLVGVVLLGTIALNIWLYISIPKTFFPEQDTGV 559
Cdd:COG0841 480 LTPALCARLLKPHPKGKKGRFfRAFNRGFDRLTRGYGRLLRWALRHRKLTLLVALALLALSVLLFGRLPTEFFPEEDQGQ 559
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 560 LMGGIQADQSISFQAMRGKLQDFMKIIRDDPAVDNVTGFTG----GSRVNSGMMFITLKPRDERSETAQQIIDRLRVKLA 635
Cdd:COG0841 560 IIVSVQLPPGTSLERTEAVVRQVEEILLEVPEVESVFSVVGfsggGSGSNSGTIFVTLKPWDERDRSADEIIARLREKLA 639
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 636 KEPGANLFLMAVQDirvGGRQSNASYQYTLLSDDLAALREWEPKIRKKLATLPELADVNSDQQDNGAEMNLVYDRDTMAR 715
Cdd:COG0841 640 KIPGARVFVFQPPA---GGLGSGAPIEVQLQGDDLEELAAAAEKLLAALRQIPGLVDVRSDLQLGKPELQLDIDREKAAA 716
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 716 LGIDVQAANSLLNNAFGQRQISTIYQPMNQYKVVMEVDPRYTQDISALEKMFVINNEGKAIPLSYFAKWQPANAPLSVNH 795
Cdd:COG0841 717 LGVTVADVASTLRAALGGRYVNDFNRGGREYDVRVQAPEEDRNSPEDLENLYVRTPDGEMVPLSSVATIEEGTGPSSINR 796
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 796 QGLSAASTISFNLPTGKSLSDASAAIDRAMTQLGVPSTVRGIFAGTAQVFQETMNSQVILIIAAIATVYIVLGILYESYV 875
Cdd:COG0841 797 YNGQRSVTVSANLAPGVSLGEALAAIEELAAELKLPPGVSIEFTGQAEEEQESFSSLGLAFLLALLLVYLVLAAQFESFI 876
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 876 HPLTILSTLPSAGVGALLALELFNAPFSLIALIGIMLLIGIVKKNAIMMVDFALEAQRHGnLTPQEAIFQACLLRFRPIM 955
Cdd:COG0841 877 QPLIILLTVPLALIGALLGLLLTGTPLNIYSQIGLIMLIGIVVKNAILLVDFANQLREEG-MSLREAILEAARLRLRPIL 955
|
970 980 990 1000 1010 1020
....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 956 MTTLAALFGALPLVLSGGDGSELRQPLGITIVGGLVMSQLLTLYTTPVVYLFFDRLRLRF 1015
Cdd:COG0841 956 MTSLATILGLLPLALGTGAGAEFRQPLGIAVIGGLLFSTLLTLFVVPVLYVLLDRLRRRL 1015
|
|
| PRK10503 |
PRK10503 |
MdtB/MuxB family multidrug efflux RND transporter permease subunit; |
6-1025 |
0e+00 |
|
MdtB/MuxB family multidrug efflux RND transporter permease subunit;
Pssm-ID: 182501 [Multi-domain] Cd Length: 1040 Bit Score: 1075.52 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 6 LFIYRPVATILLSVAITLCGILGFRMLPVAPLPQVDFPVIMVSASLPGASPETMASSVATPLERSLGRIAGVSEMTSSSS 85
Cdd:PRK10503 15 LFILRPVATTLLMVAILLAGIIGYRALPVSALPEVDYPTIQVVTLYPGASPDVMTSAVTAPLERQFGQMSGLKQMSSQSS 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 86 LGSTRIILQFDFDRDINGAARDVQAAINAAQSLLPSGMPSRPTYRKANPSDAPIMILTLTSDTYSQGELYDFASTQLAPT 165
Cdd:PRK10503 95 GGASVITLQFQLTLPLDVAEQEVQAAINAATNLLPSDLPNPPVYSKVNPADPPIMTLAVTSTAMPMTQVEDMVETRVAQK 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 166 ISQIDGVGDVDVGGSSLPAVRVGLNPQALFNQGVSLDDVRSAISNANVRKPQGALEDSTHRWQIQTNDELKTAAEYQPLI 245
Cdd:PRK10503 175 ISQVSGVGLVTLSGGQRPAVRVKLNAQAIAALGLTSETVRTAITGANVNSAKGSLDGPTRAVTLSANDQMQSAEEYRQLI 254
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 246 IHYNNGGAVRLGDVATVTDSVQDVRNAGMTNAKPAILLMIRKLPEANIIQTVDSIRAKLPELQETIPAAIDLQIAQDRSP 325
Cdd:PRK10503 255 IAYQNGAPIRLGDVATVEQGAENSWLGAWANKQQAIVMNVQRQPGANIIATADSIRQMLPQLTESLPKSVKVTVLSDRTT 334
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 326 TIRASLEEVEQTLIISVALVILVVFLFLRSGRATIIPAVAVPVSLIGTFAAMYLCGFSLNNLSLMALTIATGFVVDDAIV 405
Cdd:PRK10503 335 NIRASVDDTQFELMLAIALVVMIIYLFLRNIPATIIPGVAVPLSLIGTFAVMVFLDFSINNLTLMALTIATGFVVDDAIV 414
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 406 VLENIARHLEAGMKPLQAALQGTREVGFTVLSMSLSLVAVFLPLLLMGGLPGRLLREFAVTLSVAIGISLLVSLTLTPMM 485
Cdd:PRK10503 415 VIENISRYIEKGEKPLAAALKGAGEIGFTIISLTFSLIAVLIPLLFMGDIVGRLFREFAVTLAVAILISAVVSLTLTPMM 494
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 486 CGWMLKASKPREQKRL-RGFGRMLVALQQGYGKSLKWVLNHTRLVGVVLLGTIALNIWLYISIPKTFFPEQDTGVLMGGI 564
Cdd:PRK10503 495 CARMLSQESLRKQNRFsRASERMFDRVIAAYGRGLAKVLNHPWLTLSVALSTLLLTVLLWIFIPKGFFPVQDNGIIQGTL 574
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 565 QADQSISFQAMRGKLQDFMKIIRDDPAVDNVTGFTG----GSRVNSGMMFITLKPRDERSETAQQIIDRLRVKLAKEPGA 640
Cdd:PRK10503 575 QAPQSSSFANMAQRQRQVADVILQDPAVQSLTSFVGvdgtNPSLNSARLQINLKPLDERDDRVQKVIARLQTAVAKVPGV 654
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 641 NLFLMAVQDIRVGGRQSNASYQYTLLSDDLAALREWEPKIRKKLATLPELADVNSDQQDNGAEMNLVYDRDTMARLGIDV 720
Cdd:PRK10503 655 DLYLQPTQDLTIDTQVSRTQYQFTLQATSLDALSTWVPKLMEKLQQLPQLSDVSSDWQDKGLVAYVNVDRDSASRLGISM 734
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 721 QAANSLLNNAFGQRQISTIYQPMNQYKVVMEVDPRYTQDISALEKMFVINNEGKAIPLSYFAKWQPANAPLSVNHQGLSA 800
Cdd:PRK10503 735 ADVDNALYNAFGQRLISTIYTQANQYRVVLEHNTENTPGLAALDTIRLTSSDGGVVPLSSIATIEQRFGPLSINHLDQFP 814
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 801 ASTISFNLPTGKSLSDASAAIDRAMTQLGVPSTVRGIFAGTAQVFQETMNSQVILIIAAIATVYIVLGILYESYVHPLTI 880
Cdd:PRK10503 815 STTISFNVPDGYSLGDAVQAIMDTEKTLNLPADITTQFQGSTLAFQSALGSTVWLIVAAVVAMYIVLGVLYESFIHPITI 894
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 881 LSTLPSAGVGALLALELFNAPFSLIALIGIMLLIGIVKKNAIMMVDFALEAQRHGNLTPQEAIFQACLLRFRPIMMTTLA 960
Cdd:PRK10503 895 LSTLPTAGVGALLALMIAGSELDVIAIIGIILLIGIVKKNAIMMIDFALAAEREQGMSPRDAIYQACLLRFRPILMTTLA 974
|
970 980 990 1000 1010 1020
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446590158 961 ALFGALPLVLSGGDGSELRQPLGITIVGGLVMSQLLTLYTTPVVYLFFDRLRLRFSRKPKQAVTE 1025
Cdd:PRK10503 975 ALLGALPLMLSTGVGAELRRPLGICMVGGLIVSQVLTLFTTPVIYLLFDRLALYTKSRFPRHEEE 1039
|
|
| 2A0602 |
TIGR00915 |
The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins ... |
7-1025 |
4.66e-166 |
|
The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins scoring above the trusted cutoff (1000) form a tight clade within the RND (Resistance-Nodulation-Cell Division) superfamily. Proteins scoring greater than the noise cutoff (100) appear to form a larger clade, cleanly separated from more distant homologs that include cadmium/zinc/cobalt resistance transporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Unknown substrate]
Pssm-ID: 273335 [Multi-domain] Cd Length: 1044 Bit Score: 515.43 E-value: 4.66e-166
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 7 FIYRPVATILLSVAITLCGILGFRMLPVAPLPQVDFPVIMVSASLPGASPETMASSVATPLERSLGRIAGVSEMTSSS-S 85
Cdd:TIGR00915 5 FIDRPIFAWVIAIIIMLAGTLSILSLPVSQYPSIAPPAITVSASYPGASAQTVQDTVTQVIEQNMNGIDGLRYMSSSSdS 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 86 LGSTRIILQFDFDRDINGAARDVQAAINAAQSLLPSGMpSRPTYRKANPSDAPIMILTLTSD--TYSQGELYDFASTQLA 163
Cdd:TIGR00915 85 DGSMTITLTFEQGTDPDIAQVQVQNKLQLATPLLPQEV-QRQGVRVEKASSNFLMVIGLVSDdgSMTKEDLSDYAASNMV 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 164 PTISQIDGVGDVDVGgSSLPAVRVGLNPQALFNQGVSLDDVRSAISNANVRKPQG------ALEDSTHRWQIQTNDELKT 237
Cdd:TIGR00915 164 DPLSRLEGVGDVQLF-GSQYAMRIWLDPAKLNSYQLTPADVISAISAQNAQISAGqlgglpAVPGQQLNATIIAQTRLQT 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 238 AAEYQPLIIHYN-NGGAVRLGDVATVTDSVQDVRNAGMTNAKPAILLMIRKLPEANIIQTVDSIRAKLPELQETIPAAID 316
Cdd:TIGR00915 243 PEQFENILLKVNtDGSQVRLKDVARVELGGENYSISARFNGKPASGLAIKLATGANALDTAKAVKAELAVLEPFFPQGMK 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 317 LQIAQDRSPTIRASLEEVEQTLIISVALVILVVFLFLRSGRATIIPAVAVPVSLIGTFAAMYLCGFSLNNLSLMALTIAT 396
Cdd:TIGR00915 323 YVYPYDTTPFVEASIEEVVHTLIEAIVLVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFAMVLAI 402
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 397 GFVVDDAIVVLENIARHL-EAGMKPLQAALQGTREVGFTVLSMSLSLVAVFLPLLLMGGLPGRLLREFAVTLSVAIGISL 475
Cdd:TIGR00915 403 GLLVDDAIVVVENVERVMaEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMALSV 482
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 476 LVSLTLTPMMCGWMLKASKPREQKRLRG-----FGRMLVALQQGYGKSLKWVLNHTRLVGVVLLGTIALNIWLYISIPKT 550
Cdd:TIGR00915 483 LVALILTPALCATMLKPIEKGEHHEKKGgffgwFNRMFDSSTHGYENGVGKILRRRGRYLLVYVLLVGGMVFLFVRLPTS 562
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 551 FFPEQDTGVLMGGIQADQSISFQAMRGKLQDFMKIIRDDPA-----VDNVTGFT-GGSRVNSGMMFITLKPRDERS---E 621
Cdd:TIGR00915 563 FLPDEDQGVFMTIVQLPAGATAERTQAVLAQVTKYLLAKEKanvesVFTVNGFSfAGRGQNMGMAFIRLKDWEERTgkeN 642
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 622 TAQQIIDRLRVKLAKEPGANLFLMAVQDIRVGGRQSNASYQytlLSD----DLAALREWEPKIRKKLATLPELADVNSDQ 697
Cdd:TIGR00915 643 SVFAIAGRATGHFMQIKDAMVIAFVPPAILELGNATGFDFF---LQDraglGHEALLQARNQLLGLAAQNPALTRVRPNG 719
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 698 QDNGAEMNLVYDRDTMARLGIDVQAANSLLNNAFGQRQISTIYQPMNQYKVVMEVDPRYTQDISALEKMFVINNEGKAIP 777
Cdd:TIGR00915 720 LEDEPQLKIDIDREKAQALGVSIADINTTLSTAWGSSYVNDFIDRGRVKRVYVQAEEDARMSPEDINKWYVRNASGEMVP 799
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 778 LSYFA--KWQpANAPLSVNHQGLSAAStISFNLPTGKSLSDASAAIDRAMTQLGvpstvRGI-FAGTAQVFQETMN-SQV 853
Cdd:TIGR00915 800 FSAFAtvRWE-YGSPQLERYNGLPSME-ILGSAAPGVSTGQAMAAMEAIAQKLP-----PGFgFSWTGMSYEERLSgSQA 872
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 854 ILIIA-AIATVYIVLGILYESYVHPLTILSTLPSAGVGALLALELFNAPFSLIALIGIMLLIGIVKKNAIMMVDFALEAQ 932
Cdd:TIGR00915 873 PALYAlSLLVVFLCLAALYESWSIPVSVMLVVPLGIIGALLATTLRGLSNDVYFQVGLLTTIGLSAKNAILIVEFAKELM 952
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 933 RHGNlTPQEAIFQACLLRFRPIMMTTLAALFGALPLVLSGGDGSELRQPLGITIVGGLVMSQLLTLYTTPVVYLFFDRLR 1012
Cdd:TIGR00915 953 AQGK-SIVEAALEAARLRLRPILMTSLAFILGVVPLAISTGAGSGSQHAIGTGVFGGMVTATVLAIFFVPLFYVVVRRLF 1031
|
1050
....*....|...
gi 446590158 1013 LRFSRKPKQAVTE 1025
Cdd:TIGR00915 1032 KRKAHEKEMSVEH 1044
|
|
| CusA |
COG3696 |
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism]; |
10-1014 |
4.65e-148 |
|
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism];
Pssm-ID: 442911 [Multi-domain] Cd Length: 1031 Bit Score: 467.58 E-value: 4.65e-148
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 10 RPVATILLSVAITLCGILGFRMLPVAPLP-----QVdfpVIMVSAslPGASPETMASSVATPLERSLGRIAGVSEMTSSS 84
Cdd:COG3696 12 NRLLVLLLTLLLAAAGIYSLRRLPIDAFPditnvQV---QVITEA--PGLSPEEVEQQVTYPIETALNGLPGVKEVRSIS 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 85 SLGSTRIILQFDFDRDINGAARDVQAAINAAQSLLPSGmpsrptyrkANPSDAP-------IMILTLTSD--TYSQGELY 155
Cdd:COG3696 87 RFGLSVVTVIFEDGTDIYWARQLVLERLQQVREQLPAG---------VTPELGPistglgeIYQYTLESDpgKYSLMELR 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 156 DFASTQLAPTISQIdgvgdvdvggsslPAV-------------RVGLNPQALFNQGVSLDDVRSAISNANVRKPQGALED 222
Cdd:COG3696 158 TLQDWVIRPQLRSV-------------PGVaevnsfggfvkqyQVLVDPAKLRAYGLTLDDVIEALERNNANVGGGYIER 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 223 STHRWQIQTNDELKTAAEYQPLIIHYNNGGAVRLGDVATVTDSvQDVRN--AGMTNAKPAILLMIRKLPEANIIQTVDSI 300
Cdd:COG3696 225 GGQEYLVRGIGLIRSLEDIENIVVKTRNGTPVLLRDVAEVRIG-PAPRRgaATLNGEGEVVGGIVLMLKGENALEVIEAV 303
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 301 RAKLPELQETIPAAIDLQIAQDRSPTIRASLEEVEQTLIISVALVILVVFLFLRSGRATIIPAVAVPVSLIGTFAAMYLC 380
Cdd:COG3696 304 KAKLAELKPSLPEGVKIVPFYDRSDLIDRAIHTVTKNLLEGALLVILVLFLFLGNLRAALIVALAIPLSLLFAFIVMRLF 383
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 381 GFSLNNLSLMALTIATGFVVDDAIVVLENIARHLE------AGMKPLQAALQGTREVG----FTVLSMSLSLVAVFLpll 450
Cdd:COG3696 384 GISANLMSLGGLAIDFGIIVDGAVVMVENILRRLEenraagTPRERLEVVLEAAREVRrpifFATLIIILVFLPIFT--- 460
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 451 lmgglpgrllreF-----------AVTLSVAIGISLLVSLTLTPMMCGWMLKASKPREQKRLrgfgrmLVALQQGYGKSL 519
Cdd:COG3696 461 ------------LegvegklfrpmALTVIFALLGALLLSLTLVPVLASLLLRGKVPEKENPL------VRWLKRLYRPLL 522
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 520 KWVLNHTRLVGVVLLGTIALNIWLYISIPKTFFPEQDTGVLMGGIQADQSISFQAMRGKLQDFMKIIRDDPAVDNVTGFT 599
Cdd:COG3696 523 RWALRHPKLVLAVALVLLVLALALFPRLGSEFLPELDEGDLLVMATLPPGISLEESVELGQQVERILKSFPEVESVVSRT 602
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 600 GgsR---------VNSGMMFITLKPRDE--RSETAQQIIDRLRVKLAKEPGANL-FLMAVQDiRV-----GGRQSNAsyq 662
Cdd:COG3696 603 G--RaedatdpmgVNMSETFVILKPRSEwrSGRTKEELIAEMREALEQIPGVNFnFSQPIQM-RVdellsGVRADVA--- 676
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 663 YTLLSDDLAALREWEPKIRKKLATLPELADVNSDQQDNGAEMNLVYDRDTMARLGIDVQAANSLLNNAFGQRQISTIYQP 742
Cdd:COG3696 677 VKIFGDDLDVLRRLAEQIEAVLKTVPGAADVQVERVTGLPQLDIRIDRDAAARYGLNVADVQDVVETAIGGKAVGQVYEG 756
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 743 MNQYKVVMEVDPRYTQDISALEKMFVINNEGKAIPLSYFAKWQPANAPLSVNHQGLSAASTISFNLpTGKSLS----DAS 818
Cdd:COG3696 757 ERRFDIVVRLPEELRDDPEAIRNLPIPTPSGAQVPLSQVADIEVVEGPNQISRENGRRRIVVQANV-RGRDLGsfvaEAQ 835
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 819 AAIDRamtQLGVPSTVRGIFAGTAQVFQETMNSQVILIIAAIATVYIVLGILYESYVHPLTILSTLPSAGVGALLALELF 898
Cdd:COG3696 836 AKVAE---QVKLPPGYYIEWGGQFENLQRATARLAIVVPLALLLIFLLLYLAFGSVRDALLILLNVPFALIGGVLALWLR 912
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 899 NAPFSLIALIGIMLLIGIVKKNAIMMVDFALEAQRHGnLTPQEAIFQACLLRFRPIMMTTLAALFGALPLVLSGGDGSEL 978
Cdd:COG3696 913 GMPLSVSAGVGFIALFGVAVLNGVVLVSYINQLRAEG-LDLREAIIEGALERLRPVLMTALVAALGLLPMALSTGPGSEV 991
|
1050 1060 1070
....*....|....*....|....*....|....*.
gi 446590158 979 RQPLGITIVGGLVMSQLLTLYTTPVVYLFFDRLRLR 1014
Cdd:COG3696 992 QRPLATVVIGGLITSTLLTLLVLPALYLLFGRRRLR 1027
|
|
| PRK09579 |
PRK09579 |
multidrug efflux RND transporter permease subunit; |
1-1005 |
9.52e-136 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 169983 [Multi-domain] Cd Length: 1017 Bit Score: 434.65 E-value: 9.52e-136
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 1 MKFFALFIYRPVATILLSVAITLCGILGFRMLPVAPLPQVDFPVIMVSASLPGASPETMASSVATPLERSLGRIAGVSEM 80
Cdd:PRK09579 1 MAFTDPFIRRPVLASVVSLLIVLLGFQAWSKLQIRQYPQMENALITVTTAYPGANAETIQGYITQPLQQSLASAEGIDYM 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 81 TSSSSLGSTRIILQFDFDRDINGAARDVQAAINAAQSLLPSGMPSrPTYRKANPSDAPIMILTLTSDTYSQGELYDFAST 160
Cdd:PRK09579 81 TSVSRQNFSIISIYARIGADSDRLFTELLAKANEVKNQLPQDAED-PVLSKEAADASALMYISFYSEEMSNPQITDYLSR 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 161 QLAPTISQIDGVGDVDVGGSSLPAVRVGLNPQALFNQGVSLDDVRSAISNANVRKPQGALEDSTHRWQIQTNDELKTAAE 240
Cdd:PRK09579 160 VIQPKLATLPGMAEAEILGNQVFAMRLWLDPVKLAGFGLSAGDVTQAVRRYNFLSAAGEVKGEYVVTSINASTELKSAEA 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 241 YQPLIIHYNNGGAVRLGDVATVTDSVQDVRNAGMTNAKPAILLMIRKLPEANIIQTVDSIRAKLPELQETIPAAIDLQIA 320
Cdd:PRK09579 240 FAAIPVKTSGDSRVLLGDVARVEMGAENYDSISSFDGIPSVYIGIKATPSANPLDVIKEVRAIMPELESQLPPNLKVSIA 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 321 QDRSPTIRASLEEVEQTLIISVALVILVVFLFLRSGRATIIPAVAVPVSLIGTFAAMYLCGFSLNNLSLMALTIATGFVV 400
Cdd:PRK09579 320 YDATLFIQASIDEVVKTLGEAVLIVIVVVFLFLGALRSVLIPVVTIPLSMIGVLFFMQMMGYSINLLTLLAMVLAIGLVV 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 401 DDAIVVLENIARHLEAGMKPLQAALQGTREVGFTVLSMSLSLVAVFLPLLLMGGLPGRLLREFAVTLSVAIGISLLVSLT 480
Cdd:PRK09579 400 DDAIVVVENIHRHIEEGKSPFDAALEGAREIAMPVVSMTITLAAVYAPIGFLTGLTGALFKEFALTLAGAVIISGIVALT 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 481 LTPMMCGWMLKASKPREQKRLRgFGRMLVALQQGYGKSLKWVLNHTRLVGVVLLGTIALNIWLYISIPKTFFPEQDTGVL 560
Cdd:PRK09579 480 LSPMMCALLLRHEENPSGLAHR-LDRLFERLKQRYQRALHGTLNTRPVVLVFAVIVLALIPVLLKFTQSELAPEEDQGII 558
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 561 MGGIQADQSISFQAMRGKLQDFMKIIRDDPAVDNVTGFTGGSRVNSGMMFITLKPRDERSETAQQIIDRLRVKLAKEPGA 640
Cdd:PRK09579 559 FMMSSSPQPANLDYLNAYTDEFTPIFKSFPEYYSSFQINGFNGVQSGIGGFLLKPWNERERTQMELLPLVQAKLEEIPGL 638
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 641 NLFLMAVQDIRVGGRqsNASYQYTL-LSDDLAALREWEPKIRKKLATLPELADVNSDQQDNGAEMNLVYDRDTMARLGID 719
Cdd:PRK09579 639 QIFGFNLPSLPGTGE--GLPFQFVInTANDYESLLQVAQRVKQRAQESGKFAFLDIDLAFDKPEVVVDIDRAKAAQMGVS 716
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 720 VQAANSLLNNAFGQRQISTIYQPMNQYKVVMEVDPRYTQDISALEKMFVINNEGKAIPLSYFAKWQPANAPLSVNH-QGL 798
Cdd:PRK09579 717 MQDLGGTLATLLGEGEINRFTIDGRSYKVIAQVERPYRDNPGWLNNYYVKNEQGQLLPLSTLITLSDRARPRQLNQfQQL 796
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 799 SAAstisfnLPTGKSLSDASAAID--RAMTQLGVPSTVRGIFAGTAQVFQETMNSQVILIIAAIATVYIVLGILYESYVH 876
Cdd:PRK09579 797 NSA------IISGFPIVSMGEAIEtvQQIAREEAPEGFAFDYAGASRQYVQEGSALWVTFGLALAIIFLVLAAQFESFRD 870
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 877 PLTILSTLPSAGVGALLALELFNAPFSLIALIGIMLLIGIVKKNAIMMVDFALEAQRHGNLTPQEAIFQACLLRFRPIMM 956
Cdd:PRK09579 871 PLVILVTVPLSICGALIPLFLGVSSMNIYTQVGLVTLIGLISKHGILIVEFANQLRHEQGLSRREAIEEAAAIRLRPVLM 950
|
970 980 990 1000
....*....|....*....|....*....|....*....|....*....
gi 446590158 957 TTLAALFGALPLVLSGGDGSELRQPLGITIVGGLVMSQLLTLYTTPVVY 1005
Cdd:PRK09579 951 TTAAMVFGMVPLILATGAGAVSRFDIGLVIATGMSIGTLFTLFVLPCIY 999
|
|
| PRK09577 |
PRK09577 |
multidrug efflux RND transporter permease subunit; |
7-1019 |
4.34e-128 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 169981 [Multi-domain] Cd Length: 1032 Bit Score: 414.63 E-value: 4.34e-128
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 7 FIYRPVATILLSVAITLCGILGFRMLPVAPLPQVDFPVIMVSASLPGASPETMASSVATPLERSLGRIAGVSEMTSSSSL 86
Cdd:PRK09577 5 FIDRPVFAWVISLFIMLGGIFAIRALPVAQYPDIAPPVVSIYATYPGASAQVVEESVTALIEREMNGAPGLLYTSATSSA 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 87 GSTRIILQFDFDRDINGAARDVQAAINAAQSLLPSGMpSRPTYRKANPSDAPIMILTLTSDT--YSQGELYDFASTQLAP 164
Cdd:PRK09577 85 GQASLSLTFKQGVNADLAAVEVQNRLKTVEARLPEPV-RRDGIQVEKAADNIQLIVSLTSDDgrLTGVELGEYASANVLQ 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 165 TISQIDGVGDVDVGGSSLpAVRVGLNPQALFNQGVSLDDVRSAISNANVRKPQGAL------EDSTHRWQIQTNDELKTA 238
Cdd:PRK09577 164 ALRRVEGVGKVQFWGAEY-AMRIWPDPVKLAALGLTASDIASAVRAHNARVTIGDIgrsavpDSAPIAATVFADAPLKTP 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 239 AEYQPLIIHYN-NGGAVRLGDVATVTDSVQDVRNAGMTNAKPAILLMIRKLPEANIIQTVDSIRAKLPELQETIPAAIDL 317
Cdd:PRK09577 243 EDFGAIALRARaDGSALYLRDVARIEFGGNDYNYPSYVNGKTATGMGIKLAPGSNAVATEKRVRATMDELSRYFPPGVKY 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 318 QIAQDRSPTIRASLEEVEQTLIISVALVILVVFLFLRSGRATIIPAVAVPVSLIGTFAAMYLCGFSLNNLSLMALTIATG 397
Cdd:PRK09577 323 QIPYETSSFVRVSMNKVVTTLIEAGVLVFLVMFLFMQNFRATLIPTLVVPVALLGTFGVMLAAGFSINVLTMFGMVLAIG 402
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 398 FVVDDAIVVLENIARHL-EAGMKPLQAALQGTREVGFTVLSMSLSLVAVFLPLLLMGGLPGRLLREFAVTLSVAIGISLL 476
Cdd:PRK09577 403 ILVDDAIVVVENVERLMvEEGLSPYDATVKAMKQISGAIVGITVVLTSVFVPMAFFGGAVGNIYRQFALSLAVSIGFSAF 482
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 477 VSLTLTPMMCGWMLK-ASKPREQKR--LRGFGRMLVALQQGY--------GKSLKWVLNHTRLVGVVLLgtialniwLYI 545
Cdd:PRK09577 483 LALSLTPALCATLLKpVDGDHHEKRgfFGWFNRFVARSTQRYatrvgailKRPLRWLVVYGALTAAAAL--------LFT 554
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 546 SIPKTFFPEQDTGVLMGGIQADQSISFQAMRGKLQDFMKIIRDDPAVDNVTGFTG----GSRVNSGMMFITLKPRDERSE 621
Cdd:PRK09577 555 RLPTAFLPDEDQGNFMVMVIRPQGTPLAETMQSVREVESYLRRHEPVAYTFALGGfnlyGEGPNGGMIFVTLKDWKERKA 634
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 622 TAQQ---IIDRLRVKLAKEPGANLFLMAVQ-----------DIRVGGRqSNASYQytllsdDLAALREwepKIRKKLATL 687
Cdd:PRK09577 635 ARDHvqaIVARINERFAGTPNTTVFAMNSPalpdlgstsgfDFRLQDR-GGLGYA------AFVAARE---QLLAEGAKD 704
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 688 PELADVNSDQQDNGAEMNLVYDRDTMARLGIDVQAANSLLNNAFGQRQISTIYQPMNQYKVVMEVDPRYTQDISALEKMF 767
Cdd:PRK09577 705 PALTDLMFAGTQDAPQLKLDIDRAKASALGVSMDEINTTLAVMFGSDYIGDFMHGSQVRRVIVQADGRHRLDPDDVKKLR 784
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 768 VINNEGKAIPLSYFAKWQPANAPLSVNHQGLSAASTISFNLPTGKSLSDASAAIDRAMTQLGvpstvRGI-FAGTAQVFQ 846
Cdd:PRK09577 785 VRNAQGEMVPLAAFATLHWTLGPPQLTRYNGYPSFTINGSAAPGHSSGEAMAAIERIAATLP-----AGIgYAWSGQSFE 859
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 847 ETMN-SQVILIIA-AIATVYIVLGILYESYVHPLTILSTLPSAGVGALLALELFNAPFSLIALIGIMLLIGIVKKNAIMM 924
Cdd:PRK09577 860 ERLSgAQAPMLFAlSVLVVFLALAALYESWSIPFAVMLVVPLGVIGAVLGVTLRGMPNDIYFKVGLIATIGLSAKNAILI 939
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 925 VDFA--LEAQRHGNLtpqEAIFQACLLRFRPIMMTTLAALFGALPLVLSGGDGSELRQPLGITIVGGLVMSQLLTLYTTP 1002
Cdd:PRK09577 940 VEVAkdLVAQRMSLA---DAALEAARLRLRPIVMTSLAFGVGVLPLAFASGAASGAQIAIGTGVLGGVITATVLAVFLVP 1016
|
1050
....*....|....*..
gi 446590158 1003 VVYLFFDRLrLRFSRKP 1019
Cdd:PRK09577 1017 LFFVVVGRL-FDVGPRR 1032
|
|
| PRK10555 |
PRK10555 |
multidrug efflux RND transporter permease AcrD; |
7-1020 |
1.66e-119 |
|
multidrug efflux RND transporter permease AcrD;
Pssm-ID: 182544 [Multi-domain] Cd Length: 1037 Bit Score: 391.89 E-value: 1.66e-119
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 7 FIYRPVATILLSVAITLCGILGFRMLPVAPLPQVDFPVIMVSASLPGASPETMASSVATPLERSLGRIAGVSEMTS-SSS 85
Cdd:PRK10555 5 FIDRPIFAWVLAILLCLTGTLAIFSLPVEQYPDLAPPNVRITANYPGASAQTLENTVTQVIEQNMTGLDNLMYMSSqSSG 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 86 LGSTRIILQFDFDRDINGAARDVQAAINAAQSLLPSGMPSRP-TYRKANPSDAPIMILTLTSDTYSQGELYDFASTQLAP 164
Cdd:PRK10555 85 TGQASVTLSFKAGTDPDEAVQQVQNQLQSAMRKLPQAVQNQGvTVRKTGDTNILTIAFVSTDGSMDKQDIADYVASNIQD 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 165 TISQIDGVGDVDVGGSSLpAVRVGLNPQALFNQGVSLDDVRSAISNANVRKPQGAL------EDSTHRWQIQTNDELKTA 238
Cdd:PRK10555 165 PLSRVNGVGDIDAYGSQY-SMRIWLDPAKLNSFQMTTKDVTDAIESQNAQIAVGQLggtpsvDKQALNATINAQSLLQTP 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 239 AEYQPLIIHYN-NGGAVRLGDVATVTDSVQDVRNAGMTNAKPAILLMIRKLPEANIIQTVDSIRAKLPELQETIPAAIDL 317
Cdd:PRK10555 244 EQFRDITLRVNqDGSEVTLGDVATVELGAEKYDYLSRFNGKPASGLGVKLASGANEMATAKLVLNRLDELAQYFPHGLEY 323
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 318 QIAQDRSPTIRASLEEVEQTLIISVALVILVVFLFLRSGRATIIPAVAVPVSLIGTFAAMYLCGFSLNNLSLMALTIATG 397
Cdd:PRK10555 324 KVAYETTSFVKASIEDVVKTLLEAIALVFLVMYLFLQNFRATLIPTIAVPVVLMGTFSVLYAFGYSINTLTMFAMVLAIG 403
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 398 FVVDDAIVVLENIARHL-EAGMKPLQAALQGTREVGFTVLSMSLSLVAVFLPLLLMGGLPGRLLREFAVTLSVAIGISLL 476
Cdd:PRK10555 404 LLVDDAIVVVENVERIMsEEGLTPREATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGTTGAIYRQFSITIVSAMVLSVL 483
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 477 VSLTLTPMMCGWMLKASKPREQKRLRG--------FGRMLVALQQGYGK----SLKWVlnhtrLVGVVLLGTIAlniWLY 544
Cdd:PRK10555 484 VAMILTPALCATLLKPLKKGEHHGQKGffgwfnrmFNRNAERYEKGVAKilhrSLRWI-----LIYVLLLGGMV---FLF 555
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 545 ISIPKTFFPEQDTGVLMGGIQADQSISFQAMRGKLQDFMKIIRDDPAVDNVTGFT------GGSRVNSGMMFITLKPRDE 618
Cdd:PRK10555 556 LRLPTSFLPLEDRGMFTTSVQLPSGSTQQQTLKVVEKVEKYYFTHEKDNVMSVFAtvgsgpGGNGQNVARMFIRLKDWDE 635
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 619 R---SETAQQIIDRLRVKLAKEPGANLFlmAVQDIRVGGRQSNASYQYTLLS------DDLAALREwepKIRKKLATLPE 689
Cdd:PRK10555 636 RdskTGTSFAIIERATKAFNKIKEARVI--ASSPPAISGLGSSAGFDMELQDhagaghDALMAARN---QLLALAAKNPE 710
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 690 LADVNSDQQDNGAEMNLVYDRDTMARLGIDVQAANSLLNNAFGQRQISTIYQPMNQYKVVMEVDPRYTQDISALEKMFVI 769
Cdd:PRK10555 711 LTRVRHNGLDDSPQLQIDIDQRKAQALGVSIDDINDTLQTAWGSSYVNDFMDRGRVKKVYVQAAAPYRMLPDDINLWYVR 790
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 770 NNEGKAIPLSYFA--KWQpANAPLSVNHQGLSAASTISFNLPtGKSLSDASAAIDRAMTQLgvPSTVRgiFAGTAQVFQE 847
Cdd:PRK10555 791 NKDGGMVPFSAFAtsRWE-TGSPRLERYNGYSAVEIVGEAAP-GVSTGTAMDIMESLVKQL--PNGFG--LEWTAMSYQE 864
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 848 TMN-SQVILIIA-AIATVYIVLGILYESYVHPLTILSTLPSAGVGALLALELFNAPFSLIALIGIMLLIGIVKKNAIMMV 925
Cdd:PRK10555 865 RLSgAQAPALYAiSLLVVFLCLAALYESWSVPFSVMLVVPLGVIGALLATWMRGLENDVYFQVGLLTVIGLSAKNAILIV 944
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 926 DFALEAQRHGNlTPQEAIFQACLLRFRPIMMTTLAALFGALPLVLSGGDGSELRQPLGITIVGGLVMSQLLTLYTTPvvy 1005
Cdd:PRK10555 945 EFANEMNQKGH-DLFEATLHASRQRLRPILMTSLAFIFGVLPMATSTGAGSGSQHAVGTGVMGGMISATILAIFFVP--- 1020
|
1050
....*....|....*
gi 446590158 1006 LFFDRLRLRFSRKPK 1020
Cdd:PRK10555 1021 LFFVLVRRRFPLKPR 1035
|
|
| PRK15127 |
PRK15127 |
multidrug efflux RND transporter permease subunit AcrB; |
6-1018 |
6.41e-115 |
|
multidrug efflux RND transporter permease subunit AcrB;
Pssm-ID: 185081 [Multi-domain] Cd Length: 1049 Bit Score: 379.63 E-value: 6.41e-115
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 6 LFIYRPVATILLSVAITLCGILGFRMLPVAPLPQVDFPVIMVSASLPGASPETMASSVATPLERSLGRIAGVSEMTSSS- 84
Cdd:PRK15127 4 FFIDRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVTISASYPGADAKTVQDTVTQVIEQNMNGIDNLMYMSSNSd 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 85 SLGSTRIILQFDFDRDINGAARDVQAAINAAQSLLPSGMPSRP-TYRKANPSDAPIMILTLTSDTYSQGELYDFASTQLA 163
Cdd:PRK15127 84 STGTVQITLTFESGTDADIAQVQVQNKLQLAMPLLPQEVQQQGvSVEKSSSSFLMVVGVINTDGTMTQEDISDYVAANMK 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 164 PTISQIDGVGDVDVGGSSLpAVRVGLNPQALFNQGVSLDDVRSAISNANVRKPQGALEDSTHRWQIQTN------DELKT 237
Cdd:PRK15127 164 DPISRTSGVGDVQLFGSQY-AMRIWMNPNELNKFQLTPVDVINAIKAQNAQVAAGQLGGTPPVKGQQLNasiiaqTRLTS 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 238 AAEYQPLIIHYN-NGGAVRLGDVATVTDSVQDVRNAGMTNAKPAILLMIRKLPEANIIQTVDSIRAKLPELQETIPAAID 316
Cdd:PRK15127 243 TEEFGKILLKVNqDGSRVRLRDVAKIELGGENYDIIAEFNGQPASGLGIKLATGANALDTAAAIRAELAKMEPFFPSGLK 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 317 LQIAQDRSPTIRASLEEVEQTLIISVALVILVVFLFLRSGRATIIPAVAVPVSLIGTFAAMYLCGFSLNNLSLMALTIAT 396
Cdd:PRK15127 323 IVYPYDTTPFVKISIHEVVKTLVEAIILVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFGMVLAI 402
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 397 GFVVDDAIVVLENIARHL-EAGMKPLQAALQGTREVGFTVLSMSLSLVAVFLPLLLMGGLPGRLLREFAVTLSVAIGISL 475
Cdd:PRK15127 403 GLLVDDAIVVVENVERVMaEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMALSV 482
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 476 LVSLTLTPMMCGWMLKASKPREQKRLRG-----FGRMLVALQQGYGKSLKWVLNHTRLVGVVLLGTIALNIWLYISIPKT 550
Cdd:PRK15127 483 LVALILTPALCATMLKPIAKGDHGEGKKgffgwFNRMFEKSTHHYTDSVGNILRSTGRYLVLYLIIVVGMAYLFVRLPSS 562
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 551 FFPEQDTGVLMGGIQ----ADQSISFQAMRGKLQDFMKIIRDD-PAVDNVTGFT-GGSRVNSGMMFITLKPRDERSETAQ 624
Cdd:PRK15127 563 FLPDEDQGVFLTMVQlpagATQERTQKVLNEVTDYYLTKEKNNvESVFAVNGFGfAGRGQNTGIAFVSLKDWADRPGEEN 642
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 625 Q---IIDRLRVKLAKEPGANLFLMAVQDIRVGGRQSNASYQYT----LLSDDLAALREwepKIRKKLATLPE-LADVNSD 696
Cdd:PRK15127 643 KveaITMRATRAFSQIKDAMVFAFNLPAIVELGTATGFDFELIdqagLGHEKLTQARN---QLLGEAAKHPDmLVGVRPN 719
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 697 QQDNGAEMNLVYDRDTMARLGIDVQAANSLLNNAFGQRQISTIYQPMNQYKVVMEVDPRYTQDISALEKMFVINNEGKAI 776
Cdd:PRK15127 720 GLEDTPQFKIDIDQEKAQALGVSISDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYRMLPDDIGDWYVRAADGQMV 799
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 777 PLSYF--AKWQpANAPLSVNHQGLSAASTISFNLPtGKSLSDASAAIDRAMTQLgvPSTVRgiFAGTAQVFQETM--NSQ 852
Cdd:PRK15127 800 PFSAFssSRWE-YGSPRLERYNGLPSMEILGQAAP-GKSTGEAMELMEELASKL--PTGVG--YDWTGMSYQERLsgNQA 873
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 853 VILIIAAIATVYIVLGILYESYVHPLTILSTLPSAGVGALLALELFNAPFSLIALIGIMLLIGIVKKNAIMMVDFALEAQ 932
Cdd:PRK15127 874 PALYAISLIVVFLCLAALYESWSIPFSVMLVVPLGVIGALLAATFRGLTNDVYFQVGLLTTIGLSAKNAILIVEFAKDLM 953
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 933 RHGNLTPQEAIFQACLLRFRPIMMTTLAALFGALPLVLSGGDGSELRQPLGITIVGGLVMSQLLTLYTTPVvylFFDRLR 1012
Cdd:PRK15127 954 DKEGKGLIEATLEAVRMRLRPILMTSLAFILGVMPLVISSGAGSGAQNAVGTGVMGGMVTATVLAIFFVPV---FFVVVR 1030
|
....*.
gi 446590158 1013 LRFSRK 1018
Cdd:PRK15127 1031 RRFSRK 1036
|
|
| 2A0601 |
TIGR00914 |
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation ... |
15-1022 |
5.32e-81 |
|
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation antiporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Detoxification, Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 129992 [Multi-domain] Cd Length: 1051 Bit Score: 285.50 E-value: 5.32e-81
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 15 ILLSVAITLCGILGFRMLPVAPLPQVDFPVIMVSASLPGASPETMASSVATPLERSLGRIAGVSEMTSSSSLGSTRIILQ 94
Cdd:TIGR00914 17 LLATLVMAILGIWSYNRLPIDAVPDITNVQVQINTSAPGYSPLEVEQRVTYPIETAMAGLPGLETTRSLSRYGLSQVTVI 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 95 FDFDRDINGAARDVQAAINAAQSLLPSGMpsRPTYRKANPSDAPIMILTLTSD---TYSQGELYDFA---STQ---LAPT 165
Cdd:TIGR00914 97 FKDGTDLYFARQLVNERLQQARDNLPEGV--SPEMGPISTGLGEIFLYTVEAEegaRKKDGGAYTLTdlrTIQdwiIRPQ 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 166 ISQIDGVGDVDVGGSSLPAVRVGLNPQALFNQGVSLDDVRSAISNANVRKPQGALEDSTHRWQIQTNDELKTAAEYQPLI 245
Cdd:TIGR00914 175 LRTVPGVAEVNSIGGYVKQFLVAPDPEKLAAYGLSLADVVNALERNNQNVGAGYIERRGEQYLVRAPGQVQSMDDIRNIV 254
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 246 IHYNNGGAVRLGDVATVTDSVQDVRNAGMTNAKPAILLMIRKLPEANIIQTVDSIRAKLPELQETIPAAIDLQIAQDRSP 325
Cdd:TIGR00914 255 IATGEGVPIRIRDVARVQIGKELRTGAATENGKEVVLGTVFMLIGENSRTVAQAVGDKLETINKTLPEGVEIVTTYDRSQ 334
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 326 TIRASLEEVEQTLIISVALVILVVFLFLRSGRATIIPAVAVPVSLIGTFAAMYLCGFSLNNLSLMALtiATGFVVDDAIV 405
Cdd:TIGR00914 335 LVDAAIATVKKNLLEGALLVIVILFLFLGNIRAALIAATVIPLSLLITFIGMVFQGISANLMSLGAL--DFGLIVDGAVV 412
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 406 VLENIARHLEAGM----------KPLQAALQGTREVGFTVLSMSLSLVAVFLPLLLMGGLPGRLLREFAVTLSVAIGISL 475
Cdd:TIGR00914 413 IVENAHRRLAEAQhhhgrqltlkERLHEVFAASREVRRPLIFGQLIITLVFLPIFTLTGVEGKMFHPMAFTVVLALAGAM 492
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 476 LVSLTLTPMMCGWMLKASKPREQKRLrgfgrmLVALQQGYGKSLKWVLNHTRLVGVVLLGTIALNIWLYISIPKTFFPEQ 555
Cdd:TIGR00914 493 ILSLTFVPAAVALFIRGKVAEKENRL------MRVLKRRYEPLLERVLAWPAVVLGAAAVSIVLVVWIASRVGGEFIPSL 566
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 556 DTGVL------MGGIQADQSISFQamrgklQDFMKIIRDDPAVDNVTGFTGGSRVNSGMM-------FITLKPRDERSE- 621
Cdd:TIGR00914 567 NEGDLayqalrIPGTSLAQSVAMQ------QTLEKLIKSFPEVARVFAKTGTAEIATDPMppnasdtYIILKPESQWPEg 640
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 622 --TAQQIIDRLRVKLAKEPG-ANLFLMAVQ---DIRVGGRQSNASYQytLLSDDLAALREWEPKIRKKLATLPELADVNS 695
Cdd:TIGR00914 641 kkTKEDLIEEIQEATVRIPGnNYEFTQPIQmrfNELISGVRSDVAVK--VFGDDLDDLDATAEKISAVLKGVPGAADVKV 718
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 696 DQQDNGAEMNLVYDRDTMARLGIDVQAANSLLNNAFGQRQISTIYQPMNQYKVVMEVDPRYTQDISALEKMFVINNEGKA 775
Cdd:TIGR00914 719 EQTTGLPYLTVEIDREKAARYGLTVGDVQDTVATAVGGRMSGETFEGDRRFDIVIRLPESLRESPQALRQLPIPLPLSED 798
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 776 -----IPLSYFAKWQPANAPLSVNHQGLSAASTISFNL---PTGKSLSDASAAIDRamtQLGVPSTVRGIFAGTAQVFQE 847
Cdd:TIGR00914 799 arkqfIPLSDVADLRVSPGPNQISRENGKRRVVVSANVrgrDLGSFVDDAKKAIAE---QVKLPPGYWITWGGQFEQLQS 875
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 848 TMNSQVILIIAAIATVYIVLGILYESYVHPLTILSTLPSAGVGALLALELFNAPFSLIALIGIMLLIGIVKKNAIMMVDF 927
Cdd:TIGR00914 876 ATKRLQIVVPVTLLLIFVLLYAAFGNVKDALLVFTGIPFALTGGVFALWLRGIPLSISAAVGFIALSGVAVLNGLVMISF 955
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 928 ---ALEAQRhgnlTPQEAIFQACLLRFRPIMMTTLAALFGALPLVLSGGDGSELRQPLGITIVGGLVMSQLLTLYTTPVV 1004
Cdd:TIGR00914 956 irkLLEEGP----SLDEAVYEGALTRVRPVLMTALVASLGFVPMAIATGTGAEVQRPLATVVIGGIITATLLTLFVLPAL 1031
|
1050 1060
....*....|....*....|
gi 446590158 1005 YLFF--DRLRLRFSRKPKQA 1022
Cdd:TIGR00914 1032 YRLVhrRRHKGRKEHEPLEG 1051
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
327-1014 |
4.27e-23 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 105.71 E-value: 4.27e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 327 IRASLEEVEQTLIISVALVILVVFLFLRSGRATIIPAVAVPVSLIGTFAAMYLCGFSLNNLSLMALTIATGFVVDDAIVV 406
Cdd:COG1033 213 AEAIQSDLAIFFPLALLLILLLLFLFFRSLRGVLLPLLVVLLAVIWTLGLMGLLGIPLSPLTILVPPLLLAIGIDYGIHL 292
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 407 LENIARHLEAGMKPLQAALQGTREVGFTVLSMSLSLVAVFlplLLMGGLPGRLLREFAVTLSVAIGISLLVSLTLTPMMC 486
Cdd:COG1033 293 LNRYREERRKGLDKREALREALRKLGPPVLLTSLTTAIGF---LSLLFSDIPPIRDFGIVAAIGVLLAFLTSLTLLPALL 369
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 487 GWM-LKASKPREQKRLRGFGRMLVALqqgygksLKWVLNHTRLVGVVLLGTIALNIWLYISIPKTFFPEQDtgvlmggiq 565
Cdd:COG1033 370 SLLpRPKPKTRRLKKPPELGRLLAKL-------ARFVLRRPKVILVVALVLAVVSLYGISRLKVEYDFEDY--------- 433
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 566 adqsisfqamrgkLQDFMKIIRDDPAVDNVTGftggsrvnsGMMFITLkprdersetaqqIIDrlrvklAKEPGANLflm 645
Cdd:COG1033 434 -------------LPEDSPIRQDLDFIEENFG---------GSDPLEV------------VVD------TGEPDGLK--- 470
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 646 avqdirvggrqsnasyqytllsdDLAALREWEpKIRKKLATLPELADVNSdqqdngaemnLVydrDTMARLgidvqaaNS 725
Cdd:COG1033 471 -----------------------DPEVLKEID-RLQDYLESLPEVGKVLS----------LA---DLVKEL-------NQ 506
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 726 LLNNafGQRQISTIyqPMNQYKVVMEVDPRYTQDISALEKMfvINNEGKAIPLSYFAKWQPANAplsvnhqglsaastis 805
Cdd:COG1033 507 ALNE--GDPKYYAL--PESRELLAQLLLLLSSPPGDDLSRF--VDEDYSAARVTVRLKDLDSEE---------------- 564
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 806 fnlptgksLSDASAAIDRAMTQLGVPSTVRGIFAGTAQVFQETMN----SQVILIIAAIATVYIVLGILYESYVHPLTIL 881
Cdd:COG1033 565 --------IKALVEEVRAFLAENFPPDGVEVTLTGSAVLFAAINEsvieSQIRSLLLALLLIFLLLLLAFRSLRLGLISL 636
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 882 --STLPSAGVGALLAleLFNAPFSLIALIGIMLLIGIVKKNAIMMVDFALEAQRHGnLTPQEAIFQACLLRFRPIMMTTL 959
Cdd:COG1033 637 ipNLLPILLTFGLMG--LLGIPLNIATAVVASIALGIGVDYTIHFLSRYREERRKG-GDLEEAIRRALRTTGKAILFTSL 713
|
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|....*
gi 446590158 960 AALFGALPLVLSGGDGseLRQpLGITIVGGLVMSQLLTLYTTPVVYLFFDRLRLR 1014
Cdd:COG1033 714 TLAAGFGVLLFSSFPP--LAD-FGLLLALGLLVALLAALLLLPALLLLLDPRIAK 765
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
281-500 |
9.01e-16 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 82.22 E-value: 9.01e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 281 ILLMIRKLPEANIIQTVDSIRAKLPELQEtiPAAIDLQIAqDRSPTIRASLEEVEQTLIISVALVILVVFLFL----RSG 356
Cdd:COG1033 553 VTVRLKDLDSEEIKALVEEVRAFLAENFP--PDGVEVTLT-GSAVLFAAINESVIESQIRSLLLALLLIFLLLllafRSL 629
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 357 RATIIPAVAVPVSLIGTFAAMYLCGFSLNNLSLMALTIATGFVVDDAIVVLENIARHLEAGMKPLQAALQGTREVGFTVL 436
Cdd:COG1033 630 RLGLISLIPNLLPILLTFGLMGLLGIPLNIATAVVASIALGIGVDYTIHFLSRYREERRKGGDLEEAIRRALRTTGKAIL 709
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446590158 437 SMSLSLVAVFlplLLMGGLPGRLLREFAVTLSVAIGISLLVSLTLTPMMCGWMlkasKPREQKR 500
Cdd:COG1033 710 FTSLTLAAGF---GVLLFSSFPPLADFGLLLALGLLVALLAALLLLPALLLLL----DPRIAKK 766
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
793-1020 |
6.64e-09 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 59.87 E-value: 6.64e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 793 VNHQGLSAASTISFNLPTGKSLSDASAAIDRAMTQL------GVPSTVRGIFAGTAQVFQETMNSQVILIIAAIATVYIV 866
Cdd:COG1033 155 VSPDGKATLIVVTLDPDPLSSDLDRKEVVAEIRAIIakyedpGVEVYLTGFPVLRGDIAEAIQSDLAIFFPLALLLILLL 234
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 867 LGILYESyvhPLTILSTLPSAGVGALLAL---ELFNAPFSLIALIGIMLLIGIVKKNAIMMVDFALEAQRHGnLTPQEAI 943
Cdd:COG1033 235 LFLFFRS---LRGVLLPLLVVLLAVIWTLglmGLLGIPLSPLTILVPPLLLAIGIDYGIHLLNRYREERRKG-LDKREAL 310
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446590158 944 FQACLLRFRPIMMTTLAALFGALPLVLSGgdgSELRQPLGITIVGGLVMSQLLTLYTTPVVYLFFDRLRLRFSRKPK 1020
Cdd:COG1033 311 REALRKLGPPVLLTSLTTAIGFLSLLFSD---IPPIRDFGIVAAIGVLLAFLTSLTLLPALLSLLPRPKPKTRRLKK 384
|
|
| YdfJ |
COG2409 |
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function ... |
295-631 |
1.04e-08 |
|
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function prediction only];
Pssm-ID: 441964 [Multi-domain] Cd Length: 697 Bit Score: 59.39 E-value: 1.04e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 295 QTVDSIRAKLPELQE-------TIPAAIDLQIAQdrsptirASLEEVEQTLIISVALVILVVFLFLRSGRATIIPAVAVP 367
Cdd:COG2409 132 EAVDALRDAVAAAPApgltvyvTGPAALAADLNE-------AFEEDLGRAELITLPVALVVLLLVFRSLVAALLPLLTAG 204
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 368 VSLIGTFAAMYLCGFSLNnLSLMALTIATGFV----VDDAIVVlenIARH---LEAGMKPLQA---ALQGTREV----GF 433
Cdd:COG2409 205 LAVGVALGLLALLAAFTD-VSSFAPNLLTMLGlgvgIDYALFL---VSRYreeLRAGEDREEAvarAVATAGRAvlfsGL 280
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 434 TV----LSMSLSLVAVFlplllmgglpgrllREFAVTLSVAIGISLLVSLTLTPMMCG----WMLKASKPREQKRLRGFG 505
Cdd:COG2409 281 TVaialLGLLLAGLPFL--------------RSMGPAAAIGVAVAVLAALTLLPALLAllgrRVFWPRRPRRRRAAAPES 346
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 506 RMlvalqqgYGKSLKWVLNHTRLVGVV------LLGTIALNIWLYISIPKTF----------------FPEQDTGVLMGG 563
Cdd:COG2409 347 GF-------WRRLARAVVRRPVPVLVAavavllALALPALGLRLGLPDADSLpadspsrqgydalaehFPPGSNGPLTVV 419
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446590158 564 IQADQSISfQAMRGKLQDFMKIIRDDPAVDNVTGFTGGSRVNSGMMFITLKPRDE-RSETAQQIIDRLR 631
Cdd:COG2409 420 VESDDDLD-PADLAALDALAAALAAVPGVASVQPPTRPEGTDGDAARLQVVPDGDpDSPEAIDLVDRLR 487
|
|
| 2A067 |
TIGR00921 |
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized ... |
816-1012 |
2.54e-07 |
|
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. They fall into seven phylogenetic families, this family (2.A.6.7) consists of uncharacterised putative transporters, largely in the Archaea. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 273340 [Multi-domain] Cd Length: 719 Bit Score: 54.84 E-value: 2.54e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 816 DASAAIDRAMTQLGVPSTVRGIFAGTAQVFQETMNSQVILIIAAIATVYIVLGILYESYVHPLTILSTLPSAGVGALLAL 895
Cdd:TIGR00921 159 DVERSLERTNPPSGKFLDVTGSPAINYDIEREFGKDMGTTMAISGILVVLVLLLDFKRWWRPLLPLVIILFGVAWVLGIM 238
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 896 ELFNAPFSLIALIGIMLLIGIVKKNAIMMVDfALEAQRHGNLTPQEAIFQACLLRFRPIMMTTLAALFGALPLVLSggdG 975
Cdd:TIGR00921 239 GWLGIPLYATTLLAVPMLIGVGIDYGIQTLN-RYEEERDIGRAKGEAIVTAVRRTGRAVLIALLTTSAGFAALALS---E 314
|
170 180 190
....*....|....*....|....*....|....*..
gi 446590158 976 SELRQPLGITIVGGLVMSQLLTLYTTPVVYLFFDRLR 1012
Cdd:TIGR00921 315 FPMVSEFGLGLVAGLITAYLLTLLVLPALLQSIDIGR 351
|
|
| 2A067 |
TIGR00921 |
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized ... |
324-483 |
3.04e-07 |
|
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. They fall into seven phylogenetic families, this family (2.A.6.7) consists of uncharacterised putative transporters, largely in the Archaea. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 273340 [Multi-domain] Cd Length: 719 Bit Score: 54.46 E-value: 3.04e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 324 SPTIRASLEEVEQ-----TLIISVALVILVVFLFLRSGRATIIPAVAVPVSLIGTFAAMYLCGFSLNNLSLMALTIATGF 398
Cdd:TIGR00921 180 SPAINYDIEREFGkdmgtTMAISGILVVLVLLLDFKRWWRPLLPLVIILFGVAWVLGIMGWLGIPLYATTLLAVPMLIGV 259
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 399 VVDDAIVVLENIARHLEAGMKPLQAALQGTREVGFTVLSMSLSLVAVFlplLLMGGLPGRLLREFAVTLSVAIGISLLVS 478
Cdd:TIGR00921 260 GIDYGIQTLNRYEEERDIGRAKGEAIVTAVRRTGRAVLIALLTTSAGF---AALALSEFPMVSEFGLGLVAGLITAYLLT 336
|
....*
gi 446590158 479 LTLTP 483
Cdd:TIGR00921 337 LLVLP 341
|
|
| PRK13023 |
PRK13023 |
protein translocase subunit SecDF; |
292-502 |
1.82e-06 |
|
protein translocase subunit SecDF;
Pssm-ID: 171842 [Multi-domain] Cd Length: 758 Bit Score: 51.93 E-value: 1.82e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 292 NIIQTVDSIRAKLPELQETIPAAIDLQIAQDRSPTIRASL------------------EEVEQTLIISVALVILVV--FL 351
Cdd:PRK13023 216 NQVVSAPTVSGPLDTSELQIEGAFDLQAANNMAVVLRSGAlpqavtvleertiasalgEDYASAAVLAALLAALVVglFM 295
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 352 FLRSGRATIIPAVAVPVSLIGTFAAMYLCGFSLNNLSLMALTIATGFVVDDAIVVLENIARHLEAGMKPLQAALQGTREV 431
Cdd:PRK13023 296 VLSYGILGVIALVALVVNIIILTAVLSLIGASISLASIAGLVLTIGLAVDAHILIYERVREDRRKGYSVVQAMESGFYRA 375
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446590158 432 GFTVLSMSLSlvaVFLPLLLMGGLPGRLLREFAVTLSVAIGISLLVSLTLTPMMCGWMLKASKPREQKRLR 502
Cdd:PRK13023 376 LSTIVDANLT---TLIAALVLFLLGSGTVHGFALTVAIGIGTTLFTTLTFTRLLIAQWVRTAKPKEVPKRR 443
|
|
| SecD |
COG0342 |
Preprotein translocase subunit SecD [Intracellular trafficking, secretion, and vesicular ... |
314-497 |
8.24e-05 |
|
Preprotein translocase subunit SecD [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 440111 [Multi-domain] Cd Length: 434 Bit Score: 46.26 E-value: 8.24e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 314 AIDLQIAQDR--SPT-----IRASLeeveQTLIISVALVILVVFLFLRsgratiIPAVAVPVSLIG----TFAAMYLCGF 382
Cdd:COG0342 250 PAPLEIVEERtvGPTlgadsIEKGL----IAGLIGLLLVALFMLLYYR------LPGLVANIALALnvvlLLGVLSLLGA 319
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 383 slnNLSL-----MALTIATGfvVDDAIVVLENIARHLEAGmKPLQAALqgtrEVGF-------------TVLSMS----L 440
Cdd:COG0342 320 ---TLTLpgiagIILTIGMA--VDANVLIFERIREELRAG-RSLRAAI----EAGFkrafstildanvtTLIAAVvlfvL 389
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 446590158 441 SLVAVflplllmgglpgrllREFAVTLSVAIGISLLVSLTLTPMMCGWMLKASKPRE 497
Cdd:COG0342 390 GTGPV---------------KGFAVTLILGILISMFTAVPVTRPLLNLLLGRRRLKK 431
|
|
| MMPL |
pfam03176 |
MMPL family; Members of this family are putative integral membrane proteins from bacteria. ... |
312-501 |
1.03e-03 |
|
MMPL family; Members of this family are putative integral membrane proteins from bacteria. Several of the members are mycobacterial proteins. Many of the proteins contain two copies of this aligned region. The function of these proteins is not known, although it has been suggested that they may be involved in lipid transport.
Pssm-ID: 308676 [Multi-domain] Cd Length: 332 Bit Score: 42.66 E-value: 1.03e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 312 PAAI--DLQIAQDRSPTIrasleeveqTLIISVALVILVVFLFLRSGRATIIPAVAVPVSLIGTFAAM----YLCGFSLN 385
Cdd:pfam03176 129 PAATvaDLRDAGDRDLGL---------IEAVTLVVIFIILLIVYRSVVAALLPLLTVGLSLGAAQGLVailaHILGIGLS 199
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 386 NLS---LMALTIATGfvVDDAIVVLENIARHLEAGMKPLQAALQGTREVG-----------FTVLSMSLSLVAVFlplll 451
Cdd:pfam03176 200 TFAlnlLVVLLIAVG--TDYALFLVSRYREELRAGEDREEAVIRAVRGTGkvvtaagltvaIAMLALSFARLPVF----- 272
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 446590158 452 mgglpgrllREFAVTLSVAIGISLLVSLTLTPMMCG----WMLKASKPREQKRL 501
Cdd:pfam03176 273 ---------AQVGPTIAIGVLVDVLAALTLLPALLAllgrWGLWPPKRDRTARW 317
|
|
| PRK13024 |
PRK13024 |
bifunctional preprotein translocase subunit SecD/SecF; Reviewed |
329-641 |
1.29e-03 |
|
bifunctional preprotein translocase subunit SecD/SecF; Reviewed
Pssm-ID: 237276 [Multi-domain] Cd Length: 755 Bit Score: 42.91 E-value: 1.29e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 329 ASLEEVEQTL-------------IIS--VALVILVVFLFLRSGRATIIPAVAVPVSLIGTFAAMYLCGFSLNNLSLMALT 393
Cdd:PRK13024 246 APLKIIESRSvgptlgqdaidagIIAgiIGFALIFLFMLVYYGLPGLIANIALLLYIFLTLGALSSLGAVLTLPGIAGLV 325
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 394 IATGFVVDDAIVVLENIARHLEAGMKPLQAALQGTREVGFTVL--SMSLSLVAV--FLPLLLMGglpgrllREFAVTLSV 469
Cdd:PRK13024 326 LGIGMAVDANVLIFERIKEELRKGKSLKKAFKKGFKNAFSTILdsNITTLIAAAilFFFGTGPV-------KGFATTLII 398
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 470 AIGISLLVSLTLTPMMCGWMLKaskpREQKRLRGFGR---MLVALQQGYGKSLKWVLNHTRLVGVVLLGTIALniwlyIS 546
Cdd:PRK13024 399 GILASLFTAVFLTRLLLELLVK----RGDKKPFLFGVkkkKIHNINEGVTIFDRIDFVKKRKWFLIFSIVLVI-----AG 469
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 547 IPKTFFPEQDTGV-LMGG----IQADQSISFQAMRGKLqdfmkiirDDPAVDNVTGFTGGSRVNSGMmfITLKPRDERSE 621
Cdd:PRK13024 470 IIIFFIFGLNLGIdFTGGtryeIRTDQPVDLEQVRADL--------KELGLGEVNIVTFGSDNNQVL--VRTYGILSDDE 539
|
330 340
....*....|....*....|.
gi 446590158 622 TAQQ-IIDRLRVKLAKEPGAN 641
Cdd:PRK13024 540 EADTeIVAKLKNALKNDKGGT 560
|
|
| COG4258 |
COG4258 |
Predicted exporter [General function prediction only]; |
338-404 |
3.40e-03 |
|
Predicted exporter [General function prediction only];
Pssm-ID: 443400 [Multi-domain] Cd Length: 783 Bit Score: 41.38 E-value: 3.40e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446590158 338 LIISVALVILVVFLFLRSGRATIIpAVAVPV-SLIGTFAAMYLCGFSLNNLSLMALTIATGFVVDDAI 404
Cdd:COG4258 645 LLLALLLILLLLLLRLRSLRRALR-VLLPPLlAVLLTLAILGLLGIPLNLFHLIALLLVLGIGIDYAL 711
|
|
| MMPL |
pfam03176 |
MMPL family; Members of this family are putative integral membrane proteins from bacteria. ... |
786-1019 |
6.56e-03 |
|
MMPL family; Members of this family are putative integral membrane proteins from bacteria. Several of the members are mycobacterial proteins. Many of the proteins contain two copies of this aligned region. The function of these proteins is not known, although it has been suggested that they may be involved in lipid transport.
Pssm-ID: 308676 [Multi-domain] Cd Length: 332 Bit Score: 39.97 E-value: 6.56e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 786 PANAPLSVNHQGLSAASTISFNLPTGKSLSDAS-AAIDRAMTQLGVPSTVRGIFAGTAQVFQETMNSQ----VILIIAAI 860
Cdd:pfam03176 73 PDTAALFVSPDGKAAYVVVTLEGDPGTTEADESvAAVRDAVEQAPPPEGLKAYLTGPAATVADLRDAGdrdlGLIEAVTL 152
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 861 ATVYIVLGILYESYVHPLTILSTLpSAGVGALLALELFNAPFSLIAL------IGIMLLIGIVKKNAIMMVDFALEAQRH 934
Cdd:pfam03176 153 VVIFIILLIVYRSVVAALLPLLTV-GLSLGAAQGLVAILAHILGIGLstfalnLLVVLLIAVGTDYALFLVSRYREELRA 231
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 935 GnLTPQEAIFQAcllrfrpiMMTTLAALFGA--------LPLVLsggdgSELR--QPLGITIVGGLVMSQLLTLYTTPVV 1004
Cdd:pfam03176 232 G-EDREEAVIRA--------VRGTGKVVTAAgltvaiamLALSF-----ARLPvfAQVGPTIAIGVLVDVLAALTLLPAL 297
|
250
....*....|....*
gi 446590158 1005 YLFFDRLRLRFSRKP 1019
Cdd:pfam03176 298 LALLGRWGLWPPKRD 312
|
|
| 2A0604s01 |
TIGR00916 |
protein-export membrane protein, SecD/SecF family; The SecA,SecB,SecD,SecE,SecF,SecG and SecY ... |
325-479 |
8.99e-03 |
|
protein-export membrane protein, SecD/SecF family; The SecA,SecB,SecD,SecE,SecF,SecG and SecY proteins form the protein translocation appartus in prokaryotes. This family is specific for the SecD and SecF proteins. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 273336 [Multi-domain] Cd Length: 192 Bit Score: 38.39 E-value: 8.99e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 325 PTIRASL--EEVEQTLIISV-ALVILVVFLFLRSGRATIIPAVAVPVS-LIGTFAAMYLCGFSLNNLSLMALTIATGFVV 400
Cdd:TIGR00916 35 GTVGPTLggELIKAGIIALLiGLVLVLLYMLLRYEWRGAIAAIAALVHdVILILGVLSLFGATLTLPGIAGLLTIIGYSV 114
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446590158 401 DDAIVVLENI--ARHLEAGMKPLQAALQGTREVGFTVLSMSL-SLVAVFlpllLMGGLPGRLLREFAVTLSVAIGISLLV 477
Cdd:TIGR00916 115 DDTVVIFDRIreELRKYKGRTFREAINLGINQTLSRIIDTNVtTLLAVL----ALYVFGGGAIKGFALTLGIGVIAGTYS 190
|
..
gi 446590158 478 SL 479
Cdd:TIGR00916 191 SI 192
|
|
| |
