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MULTISPECIES: aldehyde oxidoreductase molybdenum-binding subunit PaoC [Enterobacteriaceae]
Protein Classification
xanthine dehydrogenase family protein molybdopterin-binding subunit ( domain architecture ID 11445946 )
xanthine dehydrogenase family protein molybdopterin-binding subunit is part of an oxidase/dehydrogenase complex acting on one or more of a variety of substrates
List of domain hits
Name
Accession
Description
Interval
E-value
peri_hyde_PaoC
NF041671 aldehyde oxidoreductase molybdenum-binding subunit PaoC; PaoC is the ...
1-732
0e+00
aldehyde oxidoreductase molybdenum-binding subunit PaoC; PaoC is the molybdopterin-cytosine-dinucleotide cofactor-binding subunit of the periplasmic aldehyde oxidoreductase PaoABC. The enzyme is known formally as carboxylate reductase (EC 1.2.99.6).
Pssm-ID: 469553 [Multi-domain]
Cd Length: 735
Bit Score: 1514.01
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 1 MKFD K PAG E NPIDQLKVVG R P H DRIDGPLKTTGTA R YAYE W H EE APNAAYGYIVG S AIAKGR L T AL D TD AA QK APGVLAV 80
Cdd:NF041671 1 MKFD T PAG T NPIDQLKVVG K P T DRIDGPLKTTGTA P YAYE R H DV APNAAYGYIVG A AIAKGR I T SI D LA AA RA APGVLAV 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 81 I TA S NAG A LGKG DK NTA R LLGGP T IEHYHQA I A L VVAETFEQARAAA S LV QAH Y R R NK GA YS LA DE K QAVNQ PP E --- G T 157
Cdd:NF041671 81 V TA L NAG K LGKG KF NTA K LLGGP E IEHYHQA V A V VVAETFEQARAAA A LV RVD Y A R EP GA FD LA AA K DSAPL PP G dpg G P 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 158 PD KN VGDF D GAF SS A A VK I DATYTTPDQSH MA MEPHAS M A V W D G N KLTLWTSNQMI D W C R T DLAKTL KV P V ENVR I ISPY 237
Cdd:NF041671 161 PD TR VGDF E GAF AA A P VK L DATYTTPDQSH AM MEPHAS I A A W E G D KLTLWTSNQMI N W G R G DLAKTL GI P K ENVR L ISPY 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 238 IGGGFGGKLFLR S DA L LAAL A ARA VK RPVKV M LPRP T I P NNTTHRPAT L Q HL RIGA DQS GKITAI S HESWSGNLPGG T PE 317
Cdd:NF041671 241 IGGGFGGKLFLR A DA V LAAL G ARA AG RPVKV A LPRP L I F NNTTHRPAT I Q RI RIGA TRD GKITAI A HESWSGNLPGG R PE 320
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 318 TAVQQ SE LLYAGANR H T GL RLA T LDLPEGNAMRAPGEAPGLMALEIA I DE L AEK A G I DPVEFRILNDTQVDP AD P T R R FS 397
Cdd:NF041671 321 TAVQQ TR LLYAGANR M T AM RLA V LDLPEGNAMRAPGEAPGLMALEIA M DE M AEK L G M DPVEFRILNDTQVDP EK P E R P FS 400
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 398 R RQL I ECLRTGA DK FGW KQ RNA T PGQVR D G E WL V G H GVAA G FRNNLL E KSGARV H L EPN G T VTVETDMTDIGTGSYTI L A 477
Cdd:NF041671 401 Q RQL V ECLRTGA ER FGW SR RNA K PGQVR E G R WL I G M GVAA A FRNNLL M KSGARV R L DRD G R VTVETDMTDIGTGSYTI I A 480
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 478 QTAAEM L GVPL EQ V A V H LGDSSFPVSAGSGGQWGAN T ST S GVYAACVKLRE MI A SAV GF DPEQSQ FADG KITN G T RS AM L 557
Cdd:NF041671 481 QTAAEM M GVPL DR V V V R LGDSSFPVSAGSGGQWGAN S ST A GVYAACVKLRE AV A QRL GF NSADAE FADG QVRA G N RS VP L 560
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 558 HE A T AGG R L I AE ES IEFG T L S K E YQQSTF AG HFVEVGV HS ATGE V RVRRMLAVCAAGRILNPKTARSQVIGAMTMG M GAA 637
Cdd:NF041671 561 AD A A AGG E L V AE DT IEFG D L A K K YQQSTF GA HFVEVGV DA ATGE T RVRRMLAVCAAGRILNPKTARSQVIGAMTMG V GAA 640
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 638 LMEELAVD D R L G Y FVNHD M AGYEVPVHADIP K QEVIFLD D TDP I SSPMKAKGVGELGLCGV S AAIANAVYNATG I RVRDY 717
Cdd:NF041671 641 LMEELAVD K R R G F FVNHD L AGYEVPVHADIP H QEVIFLD E TDP V SSPMKAKGVGELGLCGV A AAIANAVYNATG V RVRDY 720
730
....*....|....*
gi 446589685 718 PITLDKLLD K LP D V V 732
Cdd:NF041671 721 PITLDKLLD R LP E V A 735
Name
Accession
Description
Interval
E-value
peri_hyde_PaoC
NF041671 aldehyde oxidoreductase molybdenum-binding subunit PaoC; PaoC is the ...
1-732
0e+00
aldehyde oxidoreductase molybdenum-binding subunit PaoC; PaoC is the molybdopterin-cytosine-dinucleotide cofactor-binding subunit of the periplasmic aldehyde oxidoreductase PaoABC. The enzyme is known formally as carboxylate reductase (EC 1.2.99.6).
Pssm-ID: 469553 [Multi-domain]
Cd Length: 735
Bit Score: 1514.01
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 1 MKFD K PAG E NPIDQLKVVG R P H DRIDGPLKTTGTA R YAYE W H EE APNAAYGYIVG S AIAKGR L T AL D TD AA QK APGVLAV 80
Cdd:NF041671 1 MKFD T PAG T NPIDQLKVVG K P T DRIDGPLKTTGTA P YAYE R H DV APNAAYGYIVG A AIAKGR I T SI D LA AA RA APGVLAV 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 81 I TA S NAG A LGKG DK NTA R LLGGP T IEHYHQA I A L VVAETFEQARAAA S LV QAH Y R R NK GA YS LA DE K QAVNQ PP E --- G T 157
Cdd:NF041671 81 V TA L NAG K LGKG KF NTA K LLGGP E IEHYHQA V A V VVAETFEQARAAA A LV RVD Y A R EP GA FD LA AA K DSAPL PP G dpg G P 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 158 PD KN VGDF D GAF SS A A VK I DATYTTPDQSH MA MEPHAS M A V W D G N KLTLWTSNQMI D W C R T DLAKTL KV P V ENVR I ISPY 237
Cdd:NF041671 161 PD TR VGDF E GAF AA A P VK L DATYTTPDQSH AM MEPHAS I A A W E G D KLTLWTSNQMI N W G R G DLAKTL GI P K ENVR L ISPY 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 238 IGGGFGGKLFLR S DA L LAAL A ARA VK RPVKV M LPRP T I P NNTTHRPAT L Q HL RIGA DQS GKITAI S HESWSGNLPGG T PE 317
Cdd:NF041671 241 IGGGFGGKLFLR A DA V LAAL G ARA AG RPVKV A LPRP L I F NNTTHRPAT I Q RI RIGA TRD GKITAI A HESWSGNLPGG R PE 320
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 318 TAVQQ SE LLYAGANR H T GL RLA T LDLPEGNAMRAPGEAPGLMALEIA I DE L AEK A G I DPVEFRILNDTQVDP AD P T R R FS 397
Cdd:NF041671 321 TAVQQ TR LLYAGANR M T AM RLA V LDLPEGNAMRAPGEAPGLMALEIA M DE M AEK L G M DPVEFRILNDTQVDP EK P E R P FS 400
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 398 R RQL I ECLRTGA DK FGW KQ RNA T PGQVR D G E WL V G H GVAA G FRNNLL E KSGARV H L EPN G T VTVETDMTDIGTGSYTI L A 477
Cdd:NF041671 401 Q RQL V ECLRTGA ER FGW SR RNA K PGQVR E G R WL I G M GVAA A FRNNLL M KSGARV R L DRD G R VTVETDMTDIGTGSYTI I A 480
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 478 QTAAEM L GVPL EQ V A V H LGDSSFPVSAGSGGQWGAN T ST S GVYAACVKLRE MI A SAV GF DPEQSQ FADG KITN G T RS AM L 557
Cdd:NF041671 481 QTAAEM M GVPL DR V V V R LGDSSFPVSAGSGGQWGAN S ST A GVYAACVKLRE AV A QRL GF NSADAE FADG QVRA G N RS VP L 560
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 558 HE A T AGG R L I AE ES IEFG T L S K E YQQSTF AG HFVEVGV HS ATGE V RVRRMLAVCAAGRILNPKTARSQVIGAMTMG M GAA 637
Cdd:NF041671 561 AD A A AGG E L V AE DT IEFG D L A K K YQQSTF GA HFVEVGV DA ATGE T RVRRMLAVCAAGRILNPKTARSQVIGAMTMG V GAA 640
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 638 LMEELAVD D R L G Y FVNHD M AGYEVPVHADIP K QEVIFLD D TDP I SSPMKAKGVGELGLCGV S AAIANAVYNATG I RVRDY 717
Cdd:NF041671 641 LMEELAVD K R R G F FVNHD L AGYEVPVHADIP H QEVIFLD E TDP V SSPMKAKGVGELGLCGV A AAIANAVYNATG V RVRDY 720
730
....*....|....*
gi 446589685 718 PITLDKLLD K LP D V V 732
Cdd:NF041671 721 PITLDKLLD R LP E V A 735
CoxL
COG1529 Aldehyde, CO or xanthine dehydrogenase, Mo-binding subunit [Energy production and conversion]; ...
10-730
0e+00
Aldehyde, CO or xanthine dehydrogenase, Mo-binding subunit [Energy production and conversion]; Aldehyde, CO or xanthine dehydrogenase, Mo-binding subunit is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway
Pssm-ID: 441138 [Multi-domain]
Cd Length: 741
Bit Score: 693.51
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 10 NPIDQLKVV G R P HD R I DGP L K T TG T ARY AYEWH ee A P NAA Y GYI V G S AI A KG R LTAL DT D AA QKA PGV L AV I T ASNAGA L 89
Cdd:COG1529 2 SDPADFRII G K P VP R V DGP A K V TG R ARY TDDIR -- L P GML Y AAV V R S PH A HA R IKSI DT S AA LAL PGV V AV L T GEDLPG L 79
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 90 GK G DKNTA --- RL L GGPTIEHYHQAI A L VVAET F E Q AR A AA S L VQAH Y RRNKGAYSLADE - KQAVNQPP E GT P DK ----- 160
Cdd:COG1529 80 KF G LPGPD pdq PP L ADDKVRYVGEPV A A VVAET R E A AR D AA E L IKVE Y EPLPAVVDPEAA l APGAPLVH E EL P GN vaaew 159
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 161 -- NV GD F D G AF SS A A V KID ATYTTP DQS H MA MEP H A SM A V WDG N - K LT L W T S N Q MIDWC R TD LA KT L KV P V E N VR I I S P Y 237
Cdd:COG1529 160 rg ER GD V D A AF AE A D V VVE ATYTTP RLA H AP MEP R A AV A E WDG D g R LT V W A S T Q GPHLV R RA LA RA L GL P P E K VR V I A P D 239
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 238 I GGGFGGKL FLRSDAL LAALAAR AVK RPVK VM L P R PTIPNNT THR P AT L Q HL R I GAD QS GKITA IS H ESWS ----- GNLP 312
Cdd:COG1529 240 V GGGFGGKL DVYPEEV LAALAAR KLG RPVK LV L T R EEDFLAD THR H AT V Q RV R L GAD KD GKITA LR H DVVA dtgay ASFG 319
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 313 GGTPETAVQQSELL YA GA N RHTGL R LATLDL P EGN A M R A PG EAPGLM ALE I A I DELAE KA G I DPVE F R IL N DTQVDPAD P 392
Cdd:COG1529 320 EAVLPLGATMATGP YA IP N VRVEA R AVYTNT P PTG A Y R G PG RPQAAF ALE S A M DELAE EL G M DPVE L R LR N LIRPGDFP P 399
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 393 T - RRFSRRQ L I ECL RTG A DK FGW KQ R N A T P GQV R D G e W L V G H GVAA GFRNN -- LLEKSG ARV H L E P N G T VTV E T DM TDIG 469
Cdd:COG1529 400 T g QPYDSGR L A ECL EKA A EA FGW GE R R A R P AEA R A G - K L R G I GVAA YIEGS gg GGDPES ARV R L N P D G S VTV Y T GA TDIG 478
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 470 T G SY T I LAQ T AAE M LGVP L E Q V A V H LGD SSF - P VSA G S GG QWGANTST S G V YA A CV KLRE MI ---- A SAV G F DPE QSQ F A 544
Cdd:COG1529 479 Q G HE T V LAQ I AAE E LGVP P E D V R V V LGD TDL t P YGG G T GG SRSTAVGG S A V RK A AE KLRE KL lela A HLL G A DPE DLE F E 558
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 545 DG KITNGT RS AM L H E --- A TAG G R L I A EESIEFG T lske Y QQST F AG H FV EV G V HSA TGEVRV R R ML AV CAA GR IL NP KT 621
Cdd:COG1529 559 DG RVRVPG RS VS L A E laa A AYY G G L E A TGTYDPP T ---- Y PTYS F GA H VA EV E V DPE TGEVRV L R VV AV HDC GR VI NP LL 634
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 622 ARS QV I G AMTM G M G A AL M EEL AV D DR l G YFV N HDM A G Y E VP VH AD I P KQ EVIF LDDT DP i SS P MK AKGVGE L G LC GV SA A 701
Cdd:COG1529 635 VEG QV E G GVVQ G I G Q AL Y EEL VY D ED - G QLL N ANF A D Y L VP RA AD V P EI EVIF VETP DP - TN P LG AKGVGE P G TI GV AP A 712
730 740
....*....|....*....|....*....
gi 446589685 702 IANAVY N ATG I R V RD Y PIT LD K L L DK L PD 730
Cdd:COG1529 713 IANAVY D ATG V R I RD L PIT PE K V L AA L RE 741
PRK09970
PRK09970 xanthine dehydrogenase subunit XdhA; Provisional
16-728
3.16e-85
xanthine dehydrogenase subunit XdhA; Provisional
Pssm-ID: 236637 [Multi-domain]
Cd Length: 759
Bit Score: 285.44
E-value: 3.16e-85
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 16 KVV G RPHD R I D GPL K T TG T A R Y AYEWHE ea PNAA Y GYI V G S A IA K G RLTAL DT DA A QKA PGV L AV I T ----------- A S 84
Cdd:PRK09970 1 MAI G KSIM R V D AIA K V TG R A K Y TDDYVM -- AGML Y AKY V R S P IA H G KVKSI DT EE A RSL PGV E AV F T wedvpdipfpt A G 78
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 85 NAGA L GKGDKNT A - R L L GGPTIE H YHQ A I A L VVA ETFEQ A RA A AS L VQAH Y RRNK g AYSLADEKQ A VNQ PP EGTPDK N -- 161
Cdd:PRK09970 79 HPWS L DPNHRDI A d R A L LTRHVR H HGD A V A A VVA RDELT A EK A LK L IKVE Y EELP - VITDPEAAL A EGA PP IHNGRG N ll 157
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 162 ------ V G DFDGAFSS A AVKIDAT Y T TP DQS H MA ME PHA S M A VWDGN - KL T LWT S N Q MIDWC R TDLAKT L KV P VEN VR I I 234
Cdd:PRK09970 158 kqstms T G NVQQTIKA A DYQVQGH Y E TP IVQ H CH ME NVT S Y A YMEDD g RI T IVS S T Q IPHIV R RVVGQA L GI P WGK VR V I 237
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 235 S PY I GGGFG G K LFLRSDA L L A A L AARAVK RPVKV M L P R PTIPNN T TH R P A TLQHLRI G ADQS G KITAI S HESW S GN lp G G 314
Cdd:PRK09970 238 K PY V GGGFG N K QDVLEEP L A A F L TSKVGG RPVKV S L S R EECFLA T RT R H A FTIDIKM G VNRD G TLKGY S LDVL S NT -- G A 315
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 315 T pet A VQQSELLY AG A N RHTG L -------- RLA T L -- D LP EGN AMR AP G e AP GLM - A L E IAI D EL A EKA GIDPVEFR IL N 383
Cdd:PRK09970 316 Y --- A SHGHSIAS AG G N KVAY L yprcayky SSK T V yt N LP SAG AMR GY G - AP QVV f A V E SML D DA A TAL GIDPVEFR LR N 391
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 384 DTQVDP A D P T -- R R FSRRQ L I ECL RT G ADK F G W KQ R N A ---- TP G QV R D G ewl VG HGVAAGFRNNL --- LE KS GAR VHLE 454
Cdd:PRK09970 392 AAREGD A N P L sg K R IYSAG L P ECL EK G RKI F E W DK R R A eckn QQ G NL R R G --- VG VACFSYTSGTW pvg LE IA GAR LLMN 468
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 455 PN GTV T V ETDM T D IG T GS Y T ILA Q TA AE ML G V P LEQ V A V hlg D S S ----- F P VSA G SGGQWGANTSTSGVYA A CVK L R E M 529
Cdd:PRK09970 469 QD GTV Q V QSGA T E IG Q GS D T VFS Q MV AE TV G I P VSD V R V --- I S T qdtdv T P FDP G AYASRQSYVAGPAIRK A ALE L K E K 545
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 530 I ASAV ---- GFDPEQSQFA DG K I TNGTRS --------- AM -- LHEATA GG RLI AE E SI EFG T LS keyqq ST F AGH FV E V G 594
Cdd:PRK09970 546 I LAHA avml HQSAMNLDII DG H I VVKRPG eplmsleel AM da YYHPER GG QIT AE S SI KTT T NP ----- PA F GCT FV D V E 620
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 595 V HS A TGE V RVR R M L A V CAA G R ILNP KT A RS QV I G A M T MG M G A AL M EE LAV D DRL G YFV N HDMAG Y EV P VHA D I P KQ E VI F 674
Cdd:PRK09970 621 V DI A LCK V TIN R I L N V HDS G H ILNP LL A EG QV H G G M G MG I G W AL F EE MII D EKT G VVR N PNLLD Y KL P TMM D L P QL E SA F 700
730 740 750 760 770
....*....|....*....|....*....|....*....|....*....|....
gi 446589685 675 LDDTD P i S S PMKA K GV GE LGLCGVSA AI A NAV YN ATG IRVRDY P I T LDK L LDKL 728
Cdd:PRK09970 701 VEIYE P - Q S AYGH K SL GE PPIISPAP AI R NAV LM ATG VAINTL P M T PQR L FEEF 753
MoCoBD_2
pfam20256 Molybdopterin cofactor-binding domain;
407-668
1.82e-68
Molybdopterin cofactor-binding domain;
Pssm-ID: 466407 [Multi-domain]
Cd Length: 282
Bit Score: 226.26
E-value: 1.82e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 407 TGADKFGWKQ R N A TPGQVRD G EWLV G H G V A ----- A G FRNNL L EKS GA R V H L E P N G T VTV E T DM T DI G T G SY T I LAQ T AA 481
Cdd:pfam20256 1 KALELSDYDE R R A EQAEFNR G NRKR G I G I A pyveg S G LGPGA L NQA GA L V R L N P D G S VTV Y T GG T EM G Q G LE T K LAQ I AA 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 482 E M LG V P L E Q V A V HL GD SSF - P VSA G S G GQWGANTSTSG V YA A CV KLRE MI ---- A SAVGFD PE QSQ F A DGK ITNG ----- 551
Cdd:pfam20256 81 E A LG I P P E D V R V VE GD TDT v P NGG G T G ASRSTDVGGNA V LL A AE KLRE RL lkia A HLLEAS PE DLE F E DGK VYVK gdprs 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 552 - T RSAMLHE A T - A G GR L I A EES ---- IEFGTLSKEYQQSTFAG H FV EV G V HSA TGEVRV R R ML AV CAA GR IL NP KTARS Q 625
Cdd:pfam20256 161 v T FAELAAA A Y g E G VG L S A TGF ytpp DDETGQGPPFAYYPYGA H AA EV E V DPE TGEVRV L R YV AV HDC GR VI NP AIVEG Q 240
250 260 270 280
....*....|....*....|....*....|....*....|...
gi 446589685 626 VI G AMTM G M G A ALMEEL AV D DR l G YFVNHDMAG Y EV P VH ADIP 668
Cdd:pfam20256 241 IE G GFVQ G I G L ALMEEL VY D ED - G QLLTASLMD Y KI P TA ADIP 282
mam_aldehyde_ox
TIGR02969 aldehyde oxidase; Members of this family are mammalian aldehyde oxidase (EC 1.2.3.1) isozymes, ...
18-725
5.90e-32
aldehyde oxidase; Members of this family are mammalian aldehyde oxidase (EC 1.2.3.1) isozymes, closely related to xanthine dehydrogenase/oxidase.
Pssm-ID: 132014 [Multi-domain]
Cd Length: 1330
Bit Score: 133.60
E-value: 5.90e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 18 V G R P HDRID G PLKT TG T A R Y A yewh EEA P --- NAAYGYI V G S AI A KGRLTAL D TDA A QKA PGV LAV ITA SN aga L GKGDK 94
Cdd:TIGR02969 576 I G H P IMHLS G VKHA TG E A I Y C ---- DDM P avd QELFLTF V T S SR A HAKIVSI D LSE A LSL PGV VDI ITA EH --- L QDANT 648
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 95 - N T AR LL GGPTIEHYH Q AIAL V V A ETFE QA RA AA SL V QAH YR RNKGAYSLAD E kq A VNQPPEGT P DKNV -- G DF D G AF SS 171
Cdd:TIGR02969 649 f G T EK LL ATDKVHCVG Q LVCA V I A DSEV QA KQ AA KH V KIV YR DLEPLILTIE E -- A IQHKSFFE P ERKL ey G NV D E AF KV 726
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 172 AAVKIDATYTTPD Q S H MA ME PHASMA V WD G -- NKLTLWT S N Q MIDWCRTDL A K TLK V PV EN V RIISPYI GG G FGGK LFLR 249
Cdd:TIGR02969 727 VDQILEGEIHMGG Q E H FY ME TQSMLV V PK G ed QEMDVYV S T Q FPKYIQDIV A A TLK L PV NK V MCHVRRV GG A FGGK VGKT 806
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 250 S DALLAALA A RAVK - R P V KVM L P R PTIPNN T TH R PAT L QHLRI G ADQS G K I T A ISH E SW S G nlp GG TP -------- E TAV 320
Cdd:TIGR02969 807 S IMAAITAF A ANKH g R A V RCT L E R GEDMLI T GG R HPY L GKYKA G FMND G R I V A LDV E HY S N --- GG SS ldeslwvi E MGL 883
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 321 QQSELL Y AGA N - R HT G LRLA T l D LP EGN A M R AP G EAPGLMAL E IA I D E L A E K A G ID P VEF R IL N - DTQV D PADPTRRFSR 398
Cdd:TIGR02969 884 LKMDNA Y KFP N l R CR G WACR T - N LP SNT A F R GF G FPQAGLIT E AC I T E V A A K C G LS P EKV R TI N m YKEI D QTPYKQEINA 962
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 399 RQ L IE C L R TGAD K FGWKQ R NATPGQVRDGEWLVGH G V A ------- A G FRNNLLEKSG A R VH LEPN G T V T V ETDMTDI G T G 471
Cdd:TIGR02969 963 KN L FQ C W R ECMA K SSYSE R KVAVEKFNAENYWKKR G L A viplkfp V G LGSVAMGQAA A L VH IYLD G S V L V THGGIEM G Q G 1042
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 472 SY T ILA Q TAAEM L GV P LEQ va VHL GDS S --- F P VSAG SGG QWG A NTSTSG V YA AC VK L REMIASAVGFD P e Q SQFA D GKI 548
Cdd:TIGR02969 1043 VH T KMI Q VVSRE L KM P MSN -- VHL RGT S tet V P NTNA SGG SVV A DLNGLA V KD AC QT L LKRLEPIISKN P - Q GTWK D WAQ 1119
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 549 T NGTR S AM L hea T A G G RLIAE ES --- I E F G T l SKEYQQSTFAGHFV EV GVHSA TG EVRVR R MLA V CAA G RIL NP KTARS Q 625
Cdd:TIGR02969 1120 T AFDQ S IS L --- S A V G YFRGY ES nin W E K G E - GHPFEYFVYGAACS EV EIDCL TG DHKNI R TDI V MDV G HSI NP ALDIG Q 1195
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 626 V I GA MTM GMG AALM EEL AVDDR l G YFVNHDMAG Y EV P VHA DIP KQ - EVI FL DDTDPISSPMKA KG V GE L G L --- C G V SA A 701
Cdd:TIGR02969 1196 V E GA FIQ GMG LYTI EEL SYSPQ - G ILYSRGPNQ Y KI P AIC DIP TE l HIS FL PPSEHSNTLYSS KG L GE S G V flg C S V FF A 1274
730 740
....*....|....*....|....
gi 446589685 702 I AN AV YN A TGI R VRDY P IT L DKL L 725
Cdd:TIGR02969 1275 I HD AV RA A RQE R GLSG P WK L TSP L 1298
Ald_Xan_dh_C
smart01008 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Aldehyde oxidase catalyses ...
32-134
2.67e-24
Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Aldehyde oxidase catalyses the conversion of an aldehyde in the presence of oxygen and water to an acid and hydrogen peroxide. The enzyme is a homodimer, and requires FAD, molybdenum and two 2FE-2S clusters as cofactors. Xanthine dehydrogenase catalyses the hydrogenation of xanthine to urate, and also requires FAD, molybdenum and two 2FE-2S clusters as cofactors. This activity is often found in a bifunctional enzyme with xanthine oxidase activity too. The enzyme can be converted from the dehydrogenase form to the oxidase form irreversibly by proteolysis or reversibly through oxidation of sulphydryl groups.
Pssm-ID: 214971 [Multi-domain]
Cd Length: 107
Bit Score: 97.97
E-value: 2.67e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 32 TG T ARY AYEWH ee A P NAAYGYI V G S AI A KG R LTAL DT D AA QKA PGV L AV I TA SNAGA L GKGD -- KNTARL L GGPTIEHYH 109
Cdd:smart01008 1 TG E ARY GDDIR -- L P GMLHAAV V R S PV A HA R IKSI DT S AA RAM PGV V AV L TA KDVPG L NDFG pl GPDEPV L ADDKVRYVG 78
90 100
....*....|....*....|....*
gi 446589685 110 Q AI A L VVAET F E Q AR A AA SL V QAH Y 134
Cdd:smart01008 79 Q PV A A VVAET E E A AR D AA EA V KVE Y 103
Name
Accession
Description
Interval
E-value
peri_hyde_PaoC
NF041671 aldehyde oxidoreductase molybdenum-binding subunit PaoC; PaoC is the ...
1-732
0e+00
aldehyde oxidoreductase molybdenum-binding subunit PaoC; PaoC is the molybdopterin-cytosine-dinucleotide cofactor-binding subunit of the periplasmic aldehyde oxidoreductase PaoABC. The enzyme is known formally as carboxylate reductase (EC 1.2.99.6).
Pssm-ID: 469553 [Multi-domain]
Cd Length: 735
Bit Score: 1514.01
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 1 MKFD K PAG E NPIDQLKVVG R P H DRIDGPLKTTGTA R YAYE W H EE APNAAYGYIVG S AIAKGR L T AL D TD AA QK APGVLAV 80
Cdd:NF041671 1 MKFD T PAG T NPIDQLKVVG K P T DRIDGPLKTTGTA P YAYE R H DV APNAAYGYIVG A AIAKGR I T SI D LA AA RA APGVLAV 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 81 I TA S NAG A LGKG DK NTA R LLGGP T IEHYHQA I A L VVAETFEQARAAA S LV QAH Y R R NK GA YS LA DE K QAVNQ PP E --- G T 157
Cdd:NF041671 81 V TA L NAG K LGKG KF NTA K LLGGP E IEHYHQA V A V VVAETFEQARAAA A LV RVD Y A R EP GA FD LA AA K DSAPL PP G dpg G P 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 158 PD KN VGDF D GAF SS A A VK I DATYTTPDQSH MA MEPHAS M A V W D G N KLTLWTSNQMI D W C R T DLAKTL KV P V ENVR I ISPY 237
Cdd:NF041671 161 PD TR VGDF E GAF AA A P VK L DATYTTPDQSH AM MEPHAS I A A W E G D KLTLWTSNQMI N W G R G DLAKTL GI P K ENVR L ISPY 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 238 IGGGFGGKLFLR S DA L LAAL A ARA VK RPVKV M LPRP T I P NNTTHRPAT L Q HL RIGA DQS GKITAI S HESWSGNLPGG T PE 317
Cdd:NF041671 241 IGGGFGGKLFLR A DA V LAAL G ARA AG RPVKV A LPRP L I F NNTTHRPAT I Q RI RIGA TRD GKITAI A HESWSGNLPGG R PE 320
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 318 TAVQQ SE LLYAGANR H T GL RLA T LDLPEGNAMRAPGEAPGLMALEIA I DE L AEK A G I DPVEFRILNDTQVDP AD P T R R FS 397
Cdd:NF041671 321 TAVQQ TR LLYAGANR M T AM RLA V LDLPEGNAMRAPGEAPGLMALEIA M DE M AEK L G M DPVEFRILNDTQVDP EK P E R P FS 400
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 398 R RQL I ECLRTGA DK FGW KQ RNA T PGQVR D G E WL V G H GVAA G FRNNLL E KSGARV H L EPN G T VTVETDMTDIGTGSYTI L A 477
Cdd:NF041671 401 Q RQL V ECLRTGA ER FGW SR RNA K PGQVR E G R WL I G M GVAA A FRNNLL M KSGARV R L DRD G R VTVETDMTDIGTGSYTI I A 480
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 478 QTAAEM L GVPL EQ V A V H LGDSSFPVSAGSGGQWGAN T ST S GVYAACVKLRE MI A SAV GF DPEQSQ FADG KITN G T RS AM L 557
Cdd:NF041671 481 QTAAEM M GVPL DR V V V R LGDSSFPVSAGSGGQWGAN S ST A GVYAACVKLRE AV A QRL GF NSADAE FADG QVRA G N RS VP L 560
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 558 HE A T AGG R L I AE ES IEFG T L S K E YQQSTF AG HFVEVGV HS ATGE V RVRRMLAVCAAGRILNPKTARSQVIGAMTMG M GAA 637
Cdd:NF041671 561 AD A A AGG E L V AE DT IEFG D L A K K YQQSTF GA HFVEVGV DA ATGE T RVRRMLAVCAAGRILNPKTARSQVIGAMTMG V GAA 640
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 638 LMEELAVD D R L G Y FVNHD M AGYEVPVHADIP K QEVIFLD D TDP I SSPMKAKGVGELGLCGV S AAIANAVYNATG I RVRDY 717
Cdd:NF041671 641 LMEELAVD K R R G F FVNHD L AGYEVPVHADIP H QEVIFLD E TDP V SSPMKAKGVGELGLCGV A AAIANAVYNATG V RVRDY 720
730
....*....|....*
gi 446589685 718 PITLDKLLD K LP D V V 732
Cdd:NF041671 721 PITLDKLLD R LP E V A 735
CoxL
COG1529 Aldehyde, CO or xanthine dehydrogenase, Mo-binding subunit [Energy production and conversion]; ...
10-730
0e+00
Aldehyde, CO or xanthine dehydrogenase, Mo-binding subunit [Energy production and conversion]; Aldehyde, CO or xanthine dehydrogenase, Mo-binding subunit is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway
Pssm-ID: 441138 [Multi-domain]
Cd Length: 741
Bit Score: 693.51
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 10 NPIDQLKVV G R P HD R I DGP L K T TG T ARY AYEWH ee A P NAA Y GYI V G S AI A KG R LTAL DT D AA QKA PGV L AV I T ASNAGA L 89
Cdd:COG1529 2 SDPADFRII G K P VP R V DGP A K V TG R ARY TDDIR -- L P GML Y AAV V R S PH A HA R IKSI DT S AA LAL PGV V AV L T GEDLPG L 79
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 90 GK G DKNTA --- RL L GGPTIEHYHQAI A L VVAET F E Q AR A AA S L VQAH Y RRNKGAYSLADE - KQAVNQPP E GT P DK ----- 160
Cdd:COG1529 80 KF G LPGPD pdq PP L ADDKVRYVGEPV A A VVAET R E A AR D AA E L IKVE Y EPLPAVVDPEAA l APGAPLVH E EL P GN vaaew 159
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 161 -- NV GD F D G AF SS A A V KID ATYTTP DQS H MA MEP H A SM A V WDG N - K LT L W T S N Q MIDWC R TD LA KT L KV P V E N VR I I S P Y 237
Cdd:COG1529 160 rg ER GD V D A AF AE A D V VVE ATYTTP RLA H AP MEP R A AV A E WDG D g R LT V W A S T Q GPHLV R RA LA RA L GL P P E K VR V I A P D 239
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 238 I GGGFGGKL FLRSDAL LAALAAR AVK RPVK VM L P R PTIPNNT THR P AT L Q HL R I GAD QS GKITA IS H ESWS ----- GNLP 312
Cdd:COG1529 240 V GGGFGGKL DVYPEEV LAALAAR KLG RPVK LV L T R EEDFLAD THR H AT V Q RV R L GAD KD GKITA LR H DVVA dtgay ASFG 319
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 313 GGTPETAVQQSELL YA GA N RHTGL R LATLDL P EGN A M R A PG EAPGLM ALE I A I DELAE KA G I DPVE F R IL N DTQVDPAD P 392
Cdd:COG1529 320 EAVLPLGATMATGP YA IP N VRVEA R AVYTNT P PTG A Y R G PG RPQAAF ALE S A M DELAE EL G M DPVE L R LR N LIRPGDFP P 399
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 393 T - RRFSRRQ L I ECL RTG A DK FGW KQ R N A T P GQV R D G e W L V G H GVAA GFRNN -- LLEKSG ARV H L E P N G T VTV E T DM TDIG 469
Cdd:COG1529 400 T g QPYDSGR L A ECL EKA A EA FGW GE R R A R P AEA R A G - K L R G I GVAA YIEGS gg GGDPES ARV R L N P D G S VTV Y T GA TDIG 478
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 470 T G SY T I LAQ T AAE M LGVP L E Q V A V H LGD SSF - P VSA G S GG QWGANTST S G V YA A CV KLRE MI ---- A SAV G F DPE QSQ F A 544
Cdd:COG1529 479 Q G HE T V LAQ I AAE E LGVP P E D V R V V LGD TDL t P YGG G T GG SRSTAVGG S A V RK A AE KLRE KL lela A HLL G A DPE DLE F E 558
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 545 DG KITNGT RS AM L H E --- A TAG G R L I A EESIEFG T lske Y QQST F AG H FV EV G V HSA TGEVRV R R ML AV CAA GR IL NP KT 621
Cdd:COG1529 559 DG RVRVPG RS VS L A E laa A AYY G G L E A TGTYDPP T ---- Y PTYS F GA H VA EV E V DPE TGEVRV L R VV AV HDC GR VI NP LL 634
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 622 ARS QV I G AMTM G M G A AL M EEL AV D DR l G YFV N HDM A G Y E VP VH AD I P KQ EVIF LDDT DP i SS P MK AKGVGE L G LC GV SA A 701
Cdd:COG1529 635 VEG QV E G GVVQ G I G Q AL Y EEL VY D ED - G QLL N ANF A D Y L VP RA AD V P EI EVIF VETP DP - TN P LG AKGVGE P G TI GV AP A 712
730 740
....*....|....*....|....*....
gi 446589685 702 IANAVY N ATG I R V RD Y PIT LD K L L DK L PD 730
Cdd:COG1529 713 IANAVY D ATG V R I RD L PIT PE K V L AA L RE 741
PRK09970
PRK09970 xanthine dehydrogenase subunit XdhA; Provisional
16-728
3.16e-85
xanthine dehydrogenase subunit XdhA; Provisional
Pssm-ID: 236637 [Multi-domain]
Cd Length: 759
Bit Score: 285.44
E-value: 3.16e-85
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 16 KVV G RPHD R I D GPL K T TG T A R Y AYEWHE ea PNAA Y GYI V G S A IA K G RLTAL DT DA A QKA PGV L AV I T ----------- A S 84
Cdd:PRK09970 1 MAI G KSIM R V D AIA K V TG R A K Y TDDYVM -- AGML Y AKY V R S P IA H G KVKSI DT EE A RSL PGV E AV F T wedvpdipfpt A G 78
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 85 NAGA L GKGDKNT A - R L L GGPTIE H YHQ A I A L VVA ETFEQ A RA A AS L VQAH Y RRNK g AYSLADEKQ A VNQ PP EGTPDK N -- 161
Cdd:PRK09970 79 HPWS L DPNHRDI A d R A L LTRHVR H HGD A V A A VVA RDELT A EK A LK L IKVE Y EELP - VITDPEAAL A EGA PP IHNGRG N ll 157
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 162 ------ V G DFDGAFSS A AVKIDAT Y T TP DQS H MA ME PHA S M A VWDGN - KL T LWT S N Q MIDWC R TDLAKT L KV P VEN VR I I 234
Cdd:PRK09970 158 kqstms T G NVQQTIKA A DYQVQGH Y E TP IVQ H CH ME NVT S Y A YMEDD g RI T IVS S T Q IPHIV R RVVGQA L GI P WGK VR V I 237
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 235 S PY I GGGFG G K LFLRSDA L L A A L AARAVK RPVKV M L P R PTIPNN T TH R P A TLQHLRI G ADQS G KITAI S HESW S GN lp G G 314
Cdd:PRK09970 238 K PY V GGGFG N K QDVLEEP L A A F L TSKVGG RPVKV S L S R EECFLA T RT R H A FTIDIKM G VNRD G TLKGY S LDVL S NT -- G A 315
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 315 T pet A VQQSELLY AG A N RHTG L -------- RLA T L -- D LP EGN AMR AP G e AP GLM - A L E IAI D EL A EKA GIDPVEFR IL N 383
Cdd:PRK09970 316 Y --- A SHGHSIAS AG G N KVAY L yprcayky SSK T V yt N LP SAG AMR GY G - AP QVV f A V E SML D DA A TAL GIDPVEFR LR N 391
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 384 DTQVDP A D P T -- R R FSRRQ L I ECL RT G ADK F G W KQ R N A ---- TP G QV R D G ewl VG HGVAAGFRNNL --- LE KS GAR VHLE 454
Cdd:PRK09970 392 AAREGD A N P L sg K R IYSAG L P ECL EK G RKI F E W DK R R A eckn QQ G NL R R G --- VG VACFSYTSGTW pvg LE IA GAR LLMN 468
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 455 PN GTV T V ETDM T D IG T GS Y T ILA Q TA AE ML G V P LEQ V A V hlg D S S ----- F P VSA G SGGQWGANTSTSGVYA A CVK L R E M 529
Cdd:PRK09970 469 QD GTV Q V QSGA T E IG Q GS D T VFS Q MV AE TV G I P VSD V R V --- I S T qdtdv T P FDP G AYASRQSYVAGPAIRK A ALE L K E K 545
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 530 I ASAV ---- GFDPEQSQFA DG K I TNGTRS --------- AM -- LHEATA GG RLI AE E SI EFG T LS keyqq ST F AGH FV E V G 594
Cdd:PRK09970 546 I LAHA avml HQSAMNLDII DG H I VVKRPG eplmsleel AM da YYHPER GG QIT AE S SI KTT T NP ----- PA F GCT FV D V E 620
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 595 V HS A TGE V RVR R M L A V CAA G R ILNP KT A RS QV I G A M T MG M G A AL M EE LAV D DRL G YFV N HDMAG Y EV P VHA D I P KQ E VI F 674
Cdd:PRK09970 621 V DI A LCK V TIN R I L N V HDS G H ILNP LL A EG QV H G G M G MG I G W AL F EE MII D EKT G VVR N PNLLD Y KL P TMM D L P QL E SA F 700
730 740 750 760 770
....*....|....*....|....*....|....*....|....*....|....
gi 446589685 675 LDDTD P i S S PMKA K GV GE LGLCGVSA AI A NAV YN ATG IRVRDY P I T LDK L LDKL 728
Cdd:PRK09970 701 VEIYE P - Q S AYGH K SL GE PPIISPAP AI R NAV LM ATG VAINTL P M T PQR L FEEF 753
MoCoBD_2
pfam20256 Molybdopterin cofactor-binding domain;
407-668
1.82e-68
Molybdopterin cofactor-binding domain;
Pssm-ID: 466407 [Multi-domain]
Cd Length: 282
Bit Score: 226.26
E-value: 1.82e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 407 TGADKFGWKQ R N A TPGQVRD G EWLV G H G V A ----- A G FRNNL L EKS GA R V H L E P N G T VTV E T DM T DI G T G SY T I LAQ T AA 481
Cdd:pfam20256 1 KALELSDYDE R R A EQAEFNR G NRKR G I G I A pyveg S G LGPGA L NQA GA L V R L N P D G S VTV Y T GG T EM G Q G LE T K LAQ I AA 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 482 E M LG V P L E Q V A V HL GD SSF - P VSA G S G GQWGANTSTSG V YA A CV KLRE MI ---- A SAVGFD PE QSQ F A DGK ITNG ----- 551
Cdd:pfam20256 81 E A LG I P P E D V R V VE GD TDT v P NGG G T G ASRSTDVGGNA V LL A AE KLRE RL lkia A HLLEAS PE DLE F E DGK VYVK gdprs 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 552 - T RSAMLHE A T - A G GR L I A EES ---- IEFGTLSKEYQQSTFAG H FV EV G V HSA TGEVRV R R ML AV CAA GR IL NP KTARS Q 625
Cdd:pfam20256 161 v T FAELAAA A Y g E G VG L S A TGF ytpp DDETGQGPPFAYYPYGA H AA EV E V DPE TGEVRV L R YV AV HDC GR VI NP AIVEG Q 240
250 260 270 280
....*....|....*....|....*....|....*....|...
gi 446589685 626 VI G AMTM G M G A ALMEEL AV D DR l G YFVNHDMAG Y EV P VH ADIP 668
Cdd:pfam20256 241 IE G GFVQ G I G L ALMEEL VY D ED - G QLLTASLMD Y KI P TA ADIP 282
PRK09800
PRK09800 putative hypoxanthine oxidase; Provisional
13-728
1.21e-56
putative hypoxanthine oxidase; Provisional
Pssm-ID: 182084 [Multi-domain]
Cd Length: 956
Bit Score: 208.53
E-value: 1.21e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 13 D Q L K V V G RPHDRI D GPLKTT gt A RYA Y EWHEEAPN A AYGYIVG S AI A KGRL T A LD TDA A QKA PGV LA VIT AS N ------- 85
Cdd:PRK09800 167 D D L E V I G KHYPKT D AAKMVQ -- A KPC Y VEDRVTAD A CVIKMLR S PH A HALI T H LD VSK A EAL PGV VH VIT HL N cpdiyyt 244
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 86 - A G ALGKGDKNTA R LLG G PTIE H YHQAI A L VVAE TF E Q A RA A AS L VQAH Y R ----------------------------- 135
Cdd:PRK09800 245 p G G QSAPEPSPLD R RMF G KKMR H VGDRV A A VVAE SE E I A LE A LK L IDVE Y E vlkpvmsideamaedapvvhdepvvyvag 324
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 136 ------- R N KG A y SLAD E KQAV N Q P PEGT P D KN -------- V GD F D GA F SS A A V K I DA TY TTPDQSHMAM E P H ASMAVW D 200
Cdd:PRK09800 325 apdtled D N SH A - AQRG E HMII N F P IGSR P R KN iaasihgh I GD M D KG F AD A D V I I ER TY NSTQAQQCPT E T H ICFTRM D 403
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 201 G NK L TLWT S N Q MIDWC R TDL A KTLKVPVEN V RI I SPYI GGGFG G K -- LF L RS dal LA A L A ARAVK RPV KVMLP R PT - IPN 277
Cdd:PRK09800 404 G DR L VIHA S T Q VPWHL R RQV A RLVGMKQHK V HV I KERV GGGFG S K qd IL L EE --- VC A W A TCVTG RPV LFRYT R EE e FIA 480
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 278 NT THRP A TLQ h LRI GA DQS G KI TA ISHESWSGNL P G G T ----- P ETAVQQ S EL LY AGA N RHTGLRLATLDLPEGN A MRAP 352
Cdd:PRK09800 481 NT SRHV A KVT - VKL GA KKD G RL TA VKMDFRANTG P Y G N hsltv P CNGPAL S LP LY PCD N VDFQVTTYYSNICPNG A YQGY 559
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 353 G EAP G LM A LEI A ID ELAE KAG ID PV E F ---- R ILNDTQVD ---------- P ADPTRRF S R r Q L I E C LR T G ADKFG W KQ rn 418
Cdd:PRK09800 560 G APK G NF A ITM A LA ELAE QLQ ID QL E I iern R VHEGQELK ilgaigegka P TSVPSAA S C - A L E E I LR Q G REMIQ W SS -- 636
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 419 atp GQVRD G E W LV G H GVA A gfrnn LLE KSG -------- ARVH LE PN GT VT V ETDMT DIGTG SY T ILAQT AAE M L GV P LEQ 490
Cdd:PRK09800 637 --- PKPQN G D W HI G R GVA I ----- IMQ KSG ipdidqan CMIK LE SD GT FI V HSGGA DIGTG LD T VVTKL AAE V L HC P PQD 708
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 491 V A V HL GD SSF - PVSA G SGGQW G ANT S TSGVYA A CVK LRE M I ---- A SAV G FDPEQS Q F A DGKITN G TRSAMLHEAT A GG r 565
Cdd:PRK09800 709 V H V IS GD TDH a LFDK G AYASS G TCF S GNAARL A AEN LRE K I lfhg A QML G EPVADV Q L A TPGVVR G KKGEVSFGDI A HK - 787
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 566 li A E ESIE FG T L -- SKE Y QQST FA ---- GH F V EV G V HSA TGE V R VRRML A VCAA G RIL NP KT A RS Q VI GA MTMGM G AALM 639
Cdd:PRK09800 788 -- G E TGTG FG S L vg TGS Y ITPD FA fpyg AN F A EV A V NTR TGE I R LDKFY A LLDC G TPV NP EL A LG Q IY GA TLRAI G HSMS 865
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 640 EE LAV D DR l G YFVNH D MAG Y EV P VHA DIP KQEVIF L DDT D PISS P MK AK GVG E L G LC G VSA AIA N A VYN A T GI RV R DYPI 719
Cdd:PRK09800 866 EE IIY D AE - G HPLTR D LRS Y GA P KIG DIP RDFRAV L VPS D DKVG P FG AK SIS E I G VN G AAP AIA T A IHD A C GI WL R EWHF 944
....*....
gi 446589685 720 T LD K L L DK L 728
Cdd:PRK09800 945 T PE K I L TA L 953
MoCoBD_1
pfam02738 Molybdopterin cofactor-binding domain;
155-383
1.79e-55
Molybdopterin cofactor-binding domain;
Pssm-ID: 460671 [Multi-domain]
Cd Length: 244
Bit Score: 189.97
E-value: 1.79e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 155 E GT P DKNV ----- GD FDG AF SS A AVKIDAT Y T T PD Q S H MA ME PH A SM AV W D -- GNK LT LWT S N Q MIDWC R TDL A KT L KV P 227
Cdd:pfam02738 3 E EP P NNVA fhrek GD VEA AF AE A DHVVEGE Y R T GR Q E H FY ME TR A AL AV P D de DGR LT VYS S T Q GPHLV R RLV A RV L GI P 82
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 228 VEN VR I I S P YI GGGFGGK LFLRSDAL LAALAAR AVK RPVK VM L P R PTIPNN T T HR PAT L QHLRI GAD QS GKI T A ISHES - 306
Cdd:pfam02738 83 ENK VR V I V P RV GGGFGGK TQSYPEEA LAALAAR KTG RPVK WV L D R EEDMLA T G HR HPF L IKYKV GAD KD GKI L A LDVDL y 162
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 307 ---- WSGN L PGGT PE T A VQQSELL Y AGA N RHTGL R LATLDL P EGN A M R AP G EAP G LM ALE IAI DELAE KA G I DP V E F R IL 382
Cdd:pfam02738 163 adgg AYAD L SPAV PE R A LSHLDGP Y KIP N VRVDG R AVYTNT P PNG A F R GF G RPQ G MF ALE RLM DELAE EL G M DP L E L R RR 242
.
gi 446589685 383 N 383
Cdd:pfam02738 243 N 243
PLN02906
PLN02906 xanthine dehydrogenase
12-709
2.11e-35
xanthine dehydrogenase
Pssm-ID: 215491 [Multi-domain]
Cd Length: 1319
Bit Score: 144.46
E-value: 2.11e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 12 ID Q LKV VG R P HDRIDGP L KT TG T A R YA YE w HEEA PN AAYGYI V G S AIAKG R LTAL D TDA A QKA PG VLAVIT A SNAG algk 91
Cdd:PLN02906 559 VK Q GTA VG Q P EVHLSAE L QV TG E A E YA DD - IPMP PN TLHAAL V L S TKPHA R ILSI D DSE A KSS PG FAGIFL A KDVP ---- 633
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 92 GD KNTA ------ R L LGGPTIEHYH Q A I AL VVA E T F E Q A R AAA SL V QAH Y RRNKGAY S LADEKQ A VNQP P EGTPDKNV GD F 165
Cdd:PLN02906 634 GD NMIG pvvhde E L FATDVVTCVG Q V I GV VVA D T Q E N A K AAA RK V KVE Y EELPAIL S IEEAIE A GSFH P NTERRLEK GD V 713
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 166 DGA F S S AAV -- K I DATYTTPD Q S H MAM EP HA S M a VW --- D GN KLTLWT S N Q MIDWCRTDL A KT L KV P VEN V ----- RI -- 233
Cdd:PLN02906 714 ELC F A S GQC dr I I EGEVQMGG Q E H FYL EP NS S L - VW tsd S GN EVHMIS S T Q APQKHQKYV A HV L GL P MSK V vcktk RI gg 792
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 234 ------- I S PY I GGGFGGKLF L rsdallaalaara VK RPVK VM L P R PTIPNN T TH R P A T L QHLRI G ADQS GKI T A ISH E S 306
Cdd:PLN02906 793 gfggket R S AF I AAAAAVPAY L ------------- LN RPVK LT L D R DVDMMI T GQ R H A F L GKYKV G FTNE GKI L A LDL E I 859
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 307 WS -- GN --- L P G GTP E T A VQQ S ELL Y AGA N RHTGLRLATLDL P EGN A M R AP G EAP G LMAL E IA I DEL A EKAGID P V E F R I 381
Cdd:PLN02906 860 YN ng GN sld L S G AVL E R A MFH S DNV Y EIP N VRIVGNVCFTNF P SNT A F R GF G GPQ G MLIT E NW I QRI A VELNKS P E E I R E 939
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 382 L N ----------------------- D TQVDPA D PTR R fsrrqliecl R TGA D K F G ---- WK Q R N -- AT P gqvrdgewl VG 432
Cdd:PLN02906 940 M N fqgegsvthygqvlqhctlpqlw D ELKVSC D FLK R ---------- R EEV D E F N aknr WK K R G va MV P --------- TK 1000
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 433 H G VA ag F RNNLLEKS GA R VH LEPN GTV T V ETDMTDI G T G SY T IL AQ T AA EMLGV PL EQ V AV hl GDS S --- F P VSAGSGGQ 509
Cdd:PLN02906 1001 F G IS -- F TTKFMNQA GA L VH VYTD GTV L V THGGVEM G Q G LH T KV AQ V AA SAFNI PL SS V FI -- SET S tdk V P NASPTAAS 1076
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 510 WGANTSTSG V YA AC VKLREMIA savgfd P EQ S QFADGKITNGTRSAMLH -- EAT A G G RL I AEE s I E F --- GTLSKEYQQS 584
Cdd:PLN02906 1077 ASSDMYGAA V LD AC EQIKARME ------ P VA S KLNFSSFAELVTACYFQ ri DLS A H G FY I TPD - I G F dwk TGKGNPFNYF 1149
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 585 T FAGH F V EV GVHSA TG EVRV RR MLA V CAA G RIL NP KTARS Q VI GA MTM G M G AALM EEL AVD D ------ R L G YFVNHDMAG 658
Cdd:PLN02906 1150 T YGAA F A EV EIDTL TG DFHT RR VDI V MDL G YSI NP AIDIG Q IE GA FVQ G L G WVAL EEL KWG D aahkwi R P G SLFTCGPGT 1229
730 740 750 760 770
....*....|....*....|....*....|....*....|....*....|....*.
gi 446589685 659 Y EV P VHA DIP - K QE V IF L DDTDPISSPMKA K G VGE ---- L G l CG V SA AI AN A VYN A 709
Cdd:PLN02906 1230 Y KI P SVN DIP f K FN V SL L KGAPNPKAIHSS K A VGE ppff L A - AS V FF AI KD A IKA A 1284
mam_aldehyde_ox
TIGR02969 aldehyde oxidase; Members of this family are mammalian aldehyde oxidase (EC 1.2.3.1) isozymes, ...
18-725
5.90e-32
aldehyde oxidase; Members of this family are mammalian aldehyde oxidase (EC 1.2.3.1) isozymes, closely related to xanthine dehydrogenase/oxidase.
Pssm-ID: 132014 [Multi-domain]
Cd Length: 1330
Bit Score: 133.60
E-value: 5.90e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 18 V G R P HDRID G PLKT TG T A R Y A yewh EEA P --- NAAYGYI V G S AI A KGRLTAL D TDA A QKA PGV LAV ITA SN aga L GKGDK 94
Cdd:TIGR02969 576 I G H P IMHLS G VKHA TG E A I Y C ---- DDM P avd QELFLTF V T S SR A HAKIVSI D LSE A LSL PGV VDI ITA EH --- L QDANT 648
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 95 - N T AR LL GGPTIEHYH Q AIAL V V A ETFE QA RA AA SL V QAH YR RNKGAYSLAD E kq A VNQPPEGT P DKNV -- G DF D G AF SS 171
Cdd:TIGR02969 649 f G T EK LL ATDKVHCVG Q LVCA V I A DSEV QA KQ AA KH V KIV YR DLEPLILTIE E -- A IQHKSFFE P ERKL ey G NV D E AF KV 726
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 172 AAVKIDATYTTPD Q S H MA ME PHASMA V WD G -- NKLTLWT S N Q MIDWCRTDL A K TLK V PV EN V RIISPYI GG G FGGK LFLR 249
Cdd:TIGR02969 727 VDQILEGEIHMGG Q E H FY ME TQSMLV V PK G ed QEMDVYV S T Q FPKYIQDIV A A TLK L PV NK V MCHVRRV GG A FGGK VGKT 806
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 250 S DALLAALA A RAVK - R P V KVM L P R PTIPNN T TH R PAT L QHLRI G ADQS G K I T A ISH E SW S G nlp GG TP -------- E TAV 320
Cdd:TIGR02969 807 S IMAAITAF A ANKH g R A V RCT L E R GEDMLI T GG R HPY L GKYKA G FMND G R I V A LDV E HY S N --- GG SS ldeslwvi E MGL 883
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 321 QQSELL Y AGA N - R HT G LRLA T l D LP EGN A M R AP G EAPGLMAL E IA I D E L A E K A G ID P VEF R IL N - DTQV D PADPTRRFSR 398
Cdd:TIGR02969 884 LKMDNA Y KFP N l R CR G WACR T - N LP SNT A F R GF G FPQAGLIT E AC I T E V A A K C G LS P EKV R TI N m YKEI D QTPYKQEINA 962
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 399 RQ L IE C L R TGAD K FGWKQ R NATPGQVRDGEWLVGH G V A ------- A G FRNNLLEKSG A R VH LEPN G T V T V ETDMTDI G T G 471
Cdd:TIGR02969 963 KN L FQ C W R ECMA K SSYSE R KVAVEKFNAENYWKKR G L A viplkfp V G LGSVAMGQAA A L VH IYLD G S V L V THGGIEM G Q G 1042
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 472 SY T ILA Q TAAEM L GV P LEQ va VHL GDS S --- F P VSAG SGG QWG A NTSTSG V YA AC VK L REMIASAVGFD P e Q SQFA D GKI 548
Cdd:TIGR02969 1043 VH T KMI Q VVSRE L KM P MSN -- VHL RGT S tet V P NTNA SGG SVV A DLNGLA V KD AC QT L LKRLEPIISKN P - Q GTWK D WAQ 1119
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 549 T NGTR S AM L hea T A G G RLIAE ES --- I E F G T l SKEYQQSTFAGHFV EV GVHSA TG EVRVR R MLA V CAA G RIL NP KTARS Q 625
Cdd:TIGR02969 1120 T AFDQ S IS L --- S A V G YFRGY ES nin W E K G E - GHPFEYFVYGAACS EV EIDCL TG DHKNI R TDI V MDV G HSI NP ALDIG Q 1195
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 626 V I GA MTM GMG AALM EEL AVDDR l G YFVNHDMAG Y EV P VHA DIP KQ - EVI FL DDTDPISSPMKA KG V GE L G L --- C G V SA A 701
Cdd:TIGR02969 1196 V E GA FIQ GMG LYTI EEL SYSPQ - G ILYSRGPNQ Y KI P AIC DIP TE l HIS FL PPSEHSNTLYSS KG L GE S G V flg C S V FF A 1274
730 740
....*....|....*....|....
gi 446589685 702 I AN AV YN A TGI R VRDY P IT L DKL L 725
Cdd:TIGR02969 1275 I HD AV RA A RQE R GLSG P WK L TSP L 1298
Ald_Xan_dh_C
pfam01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain;
34-138
7.20e-32
Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain;
Pssm-ID: 426197 [Multi-domain]
Cd Length: 107
Bit Score: 119.64
E-value: 7.20e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 34 T ARYA Y EWHEE AP NAA YG YI V G S A IA KGRLTAL DT D AA QKA PGV L AVITA SNAGALGKGDKNTA -- R L LGGPTIE H YH Q A 111
Cdd:pfam01315 1 T GEAV Y VDDIP AP GNL YG AF V R S T IA HAKIVSI DT S AA LAL PGV V AVITA KDLPGGNYNIGPIP ld P L FATDKVR H VG Q P 80
90 100
....*....|....*....|....*..
gi 446589685 112 IA L VVA ETF E Q AR A AA S LV QAH Y RRNK 138
Cdd:pfam01315 81 IA A VVA DDE E T AR R AA K LV KVE Y EELP 107
Ald_Xan_dh_C
smart01008 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Aldehyde oxidase catalyses ...
32-134
2.67e-24
Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Aldehyde oxidase catalyses the conversion of an aldehyde in the presence of oxygen and water to an acid and hydrogen peroxide. The enzyme is a homodimer, and requires FAD, molybdenum and two 2FE-2S clusters as cofactors. Xanthine dehydrogenase catalyses the hydrogenation of xanthine to urate, and also requires FAD, molybdenum and two 2FE-2S clusters as cofactors. This activity is often found in a bifunctional enzyme with xanthine oxidase activity too. The enzyme can be converted from the dehydrogenase form to the oxidase form irreversibly by proteolysis or reversibly through oxidation of sulphydryl groups.
Pssm-ID: 214971 [Multi-domain]
Cd Length: 107
Bit Score: 97.97
E-value: 2.67e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 32 TG T ARY AYEWH ee A P NAAYGYI V G S AI A KG R LTAL DT D AA QKA PGV L AV I TA SNAGA L GKGD -- KNTARL L GGPTIEHYH 109
Cdd:smart01008 1 TG E ARY GDDIR -- L P GMLHAAV V R S PV A HA R IKSI DT S AA RAM PGV V AV L TA KDVPG L NDFG pl GPDEPV L ADDKVRYVG 78
90 100
....*....|....*....|....*
gi 446589685 110 Q AI A L VVAET F E Q AR A AA SL V QAH Y 134
Cdd:smart01008 79 Q PV A A VVAET E E A AR D AA EA V KVE Y 103
PLN00192
PLN00192 aldehyde oxidase
13-670
2.04e-19
aldehyde oxidase
Pssm-ID: 215096 [Multi-domain]
Cd Length: 1344
Bit Score: 93.63
E-value: 2.04e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 13 DQLKV VG R P HDRIDGP L KTT G T A R Y A yewh EEA P --- N AA YG YIVG S AIAKG R LTALDTDAAQKAP GVLAVIT ASN aga L 89
Cdd:PLN00192 574 NEYHP VG E P IKKVGAA L QAS G E A V Y V ---- DDI P spk N CL YG AFIY S TKPLA R VKGIKFKSNLVPQ GVLAVIT FKD --- I 646
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 90 G KG DK N -------- TAR L LGGPTIEHYH Q A IALVVA E T FEQ A RA AA S L VQAH Y R - R N KGAYS L AD E k Q AV NQ ------ PP 154
Cdd:PLN00192 647 P KG GQ N igsktifg PEP L FADEVTRCAG Q R IALVVA D T QKH A DM AA N L AVVE Y D t E N LEPPI L TV E - D AV KR sslfev PP 725
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 155 EGT P d K N VGD FDGAFSS A AV KI - D A TYTTPD Q SHMA ME PHASM A VW D - G N KLTLWT S N Q MIDWCRTDL A KT L KV P VE NVR 232
Cdd:PLN00192 726 FLY P - K P VGD ISKGMAE A DH KI l S A EIKLGS Q YYFY ME TQTAL A LP D e D N CIVVYS S T Q CPEYVHSVI A RC L GI P EH NVR 804
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 233 I I SPYI GGGFGGK L f LR S DALLA A L A AR A V K -- RPV KVM L P R P T -- I PNNTT H r P ATLQH l RI G ADQS GKITA I ------ 302
Cdd:PLN00192 805 V I TRRV GGGFGGK A - VK S MPVAT A C A LA A F K lq RPV RMY L N R K T dm I MAGGR H - P MKITY - SV G FKSD GKITA L hldili 881
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 303 --- SHESW S GNL P ggtpe TAVQQSELL Y AGANRHTGLRLATLD L PEGN AMRAPGE AP G LMAL E IA I DEL A EKAGI D PVEF 379
Cdd:PLN00192 882 nag ISPDI S PIM P ----- RNIIGALKK Y DWGALSFDIKVCKTN L SSRS AMRAPGE VQ G SYIA E AI I EHV A STLSM D VDSV 956
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 380 R IL N dtq VDPADPTRR F SRRQLI E C ---- L RTGA DK F ---- GW KQR NATPGQV - R DGE W L -------- VG H G V aagfrnn 442
Cdd:PLN00192 957 R KI N --- LHTYESLKL F YGDSAG E P seyt L PSIW DK L asss EF KQR TEMVKEF n R SNK W K krgisrvp IV H E V ------- 1026
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 443 L L EKSGAR V HLEPN G TVT VE TDMTD IG T G SY T ILA Q T AA EM LG -------- VP L EQVA V HLG D SSFPVSA G - SG G QWGAN 513
Cdd:PLN00192 1027 M L RPTPGK V SILSD G SIA VE VGGIE IG Q G LW T KVK Q M AA FG LG mikcdgge DL L DKIR V IQS D TLSMIQG G f TA G STTSE 1106
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446589685 514 T S TSG V YAA CV K L R E MIASA vgfd P E QS Q FAD G KI tng T RSAMLHE A TAGG - R L I A EESIEFGTL S K EY QQSTF A GHF VE 592
Cdd:PLN00192 1107 S S CEA V RLC CV I L V E RLKPI ---- K E RL Q EQM G SV --- T WDMLISQ A YMQS v N L S A SSYYTPDPS S M EY LNYGA A VSE VE 1179
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446589685 593 V GV hs A TGE VRVR R MLAVCAA G RI LNP KTARS Q VI GA MTM G M G AALM EE LAVDDR l G YF V NHDMAG Y EV P VHAD IPKQ 670
Cdd:PLN00192 1180 V DL -- L TGE TTIL R SDIIYDC G QS LNP AVDLG Q IE GA FVQ G I G FFML EE YTTNSD - G LV V TDGTWT Y KI P TVDT IPKQ 1254
Blast search parameters
Data Source:
Precalculated data, version = cdd.v.3.21
Preset Options: Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
