NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|446562359|ref|WP_000639705|]
View 

MULTISPECIES: Na+/H+ antiporter subunit E [Vibrio]

Protein Classification

Na+/H+ antiporter subunit E( domain architecture ID 10014032)

Na+/H+ antiporter subunit E is part of a Na+/H+ prokaryotic antiporter complex consists of seven subunits (MrpABCDEFG), which are involved in Na+ excretion

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
PRK12651 PRK12651
Na+/H+ antiporter subunit E;
1-157 7.52e-52

Na+/H+ antiporter subunit E;


:

Pssm-ID: 237159  Cd Length: 158  Bit Score: 162.32  E-value: 7.52e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446562359   1 MIYLFLNLFLATAWMLLNGDYSSLQFLLGFVVGFWALRLSQPFGLKTTYFRRFRAITTLILYFIYEMIVSVARVAWDVVT 80
Cdd:PRK12651   2 AFQLLLNIILAVLWLFLTGSFSLGNFIIGFILGLFVLFLFRRLLPARFYLRRIYKLIKLVPIFLKELIKANIDVAKIVLK 81

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446562359  81 PKHLSDPDIVYVPLDARSDLEITLLANMVSLTPGTLSLDVSEDRQYLIVHAMFAPEHQAVINDIKNGLEKRILEVTR 157
Cdd:PRK12651  82 PKLNIEPGIVAVPTDLKTDWEITLLANLITLTPGTLTLDVSDDRKKLYIHAIDVKDKEEEIREIKDSFEKILLEVFE 158
 
Name Accession Description Interval E-value
PRK12651 PRK12651
Na+/H+ antiporter subunit E;
1-157 7.52e-52

Na+/H+ antiporter subunit E;


Pssm-ID: 237159  Cd Length: 158  Bit Score: 162.32  E-value: 7.52e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446562359   1 MIYLFLNLFLATAWMLLNGDYSSLQFLLGFVVGFWALRLSQPFGLKTTYFRRFRAITTLILYFIYEMIVSVARVAWDVVT 80
Cdd:PRK12651   2 AFQLLLNIILAVLWLFLTGSFSLGNFIIGFILGLFVLFLFRRLLPARFYLRRIYKLIKLVPIFLKELIKANIDVAKIVLK 81

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446562359  81 PKHLSDPDIVYVPLDARSDLEITLLANMVSLTPGTLSLDVSEDRQYLIVHAMFAPEHQAVINDIKNGLEKRILEVTR 157
Cdd:PRK12651  82 PKLNIEPGIVAVPTDLKTDWEITLLANLITLTPGTLTLDVSDDRKKLYIHAIDVKDKEEEIREIKDSFEKILLEVFE 158
MnhE COG1863
Multisubunit Na+/H+ antiporter, MnhE subunit [Inorganic ion transport and metabolism];
3-157 1.46e-51

Multisubunit Na+/H+ antiporter, MnhE subunit [Inorganic ion transport and metabolism];


Pssm-ID: 441468  Cd Length: 162  Bit Score: 161.49  E-value: 1.46e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446562359   3 YLFLNLFLATAWMLLNGDYSSLQFLLGFVVGFWALRLSQPF-GLKTTYFRRFRAITTLILYFIYEMIVSVARVAWDVVTP 81
Cdd:COG1863    7 HLLLSLLLALVWLLLSGSFSPGNLLLGLLLALLVLLLFRRLpPPRLPYLRRPLRLLRLLLYFLWDIVVANIDVARRVLRP 86

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446562359  82 KHLSDPDIVYVPLDARSDLEITLLANMVSLTPGTLSLDVSEDRQYLIVHAMFAPEHQAVINDIKNGLEKRILEVTR 157
Cdd:COG1863   87 RLPIRPGIVAVPLRLRSDLGITLLANSITLTPGTLTVDVDDDRRTLYVHALDVDDPEALIEEIKGRYERRLLEIFE 162
MNHE pfam01899
Na+/H+ ion antiporter subunit; Subunit of a Na+/H+ Prokaryotic antiporter complex.
 7-155 2.67e-51

Na+/H+ ion antiporter subunit; Subunit of a Na+/H+ Prokaryotic antiporter complex.


Pssm-ID: 460378  Cd Length: 150  Bit Score: 160.70  E-value: 2.67e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446562359    7 NLFLATAWMLLNGDYSSLQFLLGFVVGFWALRLSQPFGLKTTYFRRF-RAITTLILYFIYEMIVSVARVAWDVVTPKHLS 85
Cdd:pfam01899   1 NLLLAVVWLLLTGSFSPGNLLLGLLLGLLVLLLLRRLLPPRPPPRRPpLGLLRLLLYFLWEIVKANIQVARLVLRPKPPI 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446562359   86 DPDIVYVPLDARSDLEITLLANMVSLTPGTLSLDVSEDRQYLIVHAMFAPEHQAVINDIKNGLEKRILEV 155
Cdd:pfam01899  81 RPGIVAVPLRLRSDLALTLLANSITLTPGTLVVDVDRDRRVLYVHVLDVDDEEAARREIKGRLERRLLEI 150
 
Name Accession Description Interval E-value
PRK12651 PRK12651
Na+/H+ antiporter subunit E;
1-157 7.52e-52

Na+/H+ antiporter subunit E;


Pssm-ID: 237159  Cd Length: 158  Bit Score: 162.32  E-value: 7.52e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446562359   1 MIYLFLNLFLATAWMLLNGDYSSLQFLLGFVVGFWALRLSQPFGLKTTYFRRFRAITTLILYFIYEMIVSVARVAWDVVT 80
Cdd:PRK12651   2 AFQLLLNIILAVLWLFLTGSFSLGNFIIGFILGLFVLFLFRRLLPARFYLRRIYKLIKLVPIFLKELIKANIDVAKIVLK 81

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446562359  81 PKHLSDPDIVYVPLDARSDLEITLLANMVSLTPGTLSLDVSEDRQYLIVHAMFAPEHQAVINDIKNGLEKRILEVTR 157
Cdd:PRK12651  82 PKLNIEPGIVAVPTDLKTDWEITLLANLITLTPGTLTLDVSDDRKKLYIHAIDVKDKEEEIREIKDSFEKILLEVFE 158
MnhE COG1863
Multisubunit Na+/H+ antiporter, MnhE subunit [Inorganic ion transport and metabolism];
3-157 1.46e-51

Multisubunit Na+/H+ antiporter, MnhE subunit [Inorganic ion transport and metabolism];


Pssm-ID: 441468  Cd Length: 162  Bit Score: 161.49  E-value: 1.46e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446562359   3 YLFLNLFLATAWMLLNGDYSSLQFLLGFVVGFWALRLSQPF-GLKTTYFRRFRAITTLILYFIYEMIVSVARVAWDVVTP 81
Cdd:COG1863    7 HLLLSLLLALVWLLLSGSFSPGNLLLGLLLALLVLLLFRRLpPPRLPYLRRPLRLLRLLLYFLWDIVVANIDVARRVLRP 86

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446562359  82 KHLSDPDIVYVPLDARSDLEITLLANMVSLTPGTLSLDVSEDRQYLIVHAMFAPEHQAVINDIKNGLEKRILEVTR 157
Cdd:COG1863   87 RLPIRPGIVAVPLRLRSDLGITLLANSITLTPGTLTVDVDDDRRTLYVHALDVDDPEALIEEIKGRYERRLLEIFE 162
MNHE pfam01899
Na+/H+ ion antiporter subunit; Subunit of a Na+/H+ Prokaryotic antiporter complex.
 7-155 2.67e-51

Na+/H+ ion antiporter subunit; Subunit of a Na+/H+ Prokaryotic antiporter complex.


Pssm-ID: 460378  Cd Length: 150  Bit Score: 160.70  E-value: 2.67e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446562359    7 NLFLATAWMLLNGDYSSLQFLLGFVVGFWALRLSQPFGLKTTYFRRF-RAITTLILYFIYEMIVSVARVAWDVVTPKHLS 85
Cdd:pfam01899   1 NLLLAVVWLLLTGSFSPGNLLLGLLLGLLVLLLLRRLLPPRPPPRRPpLGLLRLLLYFLWEIVKANIQVARLVLRPKPPI 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446562359   86 DPDIVYVPLDARSDLEITLLANMVSLTPGTLSLDVSEDRQYLIVHAMFAPEHQAVINDIKNGLEKRILEV 155
Cdd:pfam01899  81 RPGIVAVPLRLRSDLALTLLANSITLTPGTLVVDVDRDRRVLYVHVLDVDDEEAARREIKGRLERRLLEI 150
PRK08965 PRK08965
putative monovalent cation/H+ antiporter subunit E; Reviewed
 1-157 3.74e-43

putative monovalent cation/H+ antiporter subunit E; Reviewed


Pssm-ID: 181598  Cd Length: 162  Bit Score: 140.30  E-value: 3.74e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446562359   1 MIYLFLNLFLATAWMLLNGDYSSLQFLLGFVVGFWALRLSQPFGLKTTYFRRFRAITTLILYFIYEMIVSVARVAWDVVT 80
Cdd:PRK08965   6 LPQPLLSLWLALVWLLLNGSFSLGNLLLGLLLGLLIPLLLALLVPLEGRLRRPLALLRLLLVVLYDLVVSNIQVAWLILR 85

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446562359  81 PKHLSDPDIVYVPLDARSDLEITLLANMVSLTPGTLSLDVSEDRQYLIVHAMFAPEHQAVINDIKNGLEKRILEVTR 157
Cdd:PRK08965  86 PGPRPRPGFVAVPLRLRSDLALTLLANIITLTPGTVVVEISRDRRTLYVHVLDLDDPEALIREIKQRYERLLMEIFE 162
PRK12596 PRK12596
putative monovalent cation/H+ antiporter subunit E; Reviewed
 4-155 4.47e-14

putative monovalent cation/H+ antiporter subunit E; Reviewed


Pssm-ID: 105779  Cd Length: 171  Bit Score: 65.76  E-value: 4.47e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446562359   4 LFLNLFLAtaWMLLNGdYSSLQFLLGFVVGFWALRLSQPFGLKTTYFRRFRAITTLILYFIYEMIVSVARVAWDVVTPKH 83
Cdd:PRK12596  10 LFVSLVLF--WLLLNS-FTRAQFILGLVIAFGACRVMMALEPQKNHIRSPRMMIWLLYAASIDVLRSNIAVVRLILSPGR 86

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446562359  84 LSDPDIVYVPLDARSDLEITLLANMVSLTPGTLSLDVSEDRQYLIVHAMFAPEHQAVINDIKNGLEKRILEV 155
Cdd:PRK12596  87 QRHPGFVVIPLELQNRTALAVLACMITASPGTAWVDYNAARGILTIHVLDLEDAETWRHLIKERYERPLIEI 158
PRK08383 PRK08383
putative monovalent cation/H+ antiporter subunit E; Reviewed
 44-136 2.63e-11

putative monovalent cation/H+ antiporter subunit E; Reviewed


Pssm-ID: 181407  Cd Length: 168  Bit Score: 58.28  E-value: 2.63e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446562359  44 GLKTTYFRRFRAITTLILY----FIYEMIVSVARVAWDVVTPKhlSDPDIVYVPLDARSDLEITLLANMVSLTPGTLSLD 119
Cdd:PRK08383  50 GEKATRFLNPIRWLLFIAYafgpLFWGMVKANLDVAYRVITGK--IRPGIVKVPVDLENDAQYTILSNSITLTPGTLTIE 127

                         90
                 ....*....|....*..
gi 446562359 120 VSEDRQYLIVHAMFAPE 136
Cdd:PRK08383 128 ACPEEKALYVHWINVPE 144
PRK12654 PRK12654
monovalent cation/H+ antiporter subunit E;
60-152 1.80e-10

monovalent cation/H+ antiporter subunit E;


Pssm-ID: 237161  Cd Length: 151  Bit Score: 55.69  E-value: 1.80e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446562359  60 ILYFIYEMIVSVARVAWDVVTPKHLSDPDIVYVPLDARSDLEITLLANMVSLTPGTLSLDVSEDR-----QYLIVHAMFA 134
Cdd:PRK12654   8 APWLIGQIFVAGFSLIKDAFKGDKNFNPVVVRYPLRVTKDWQITALAASITATPGTLSLGLREPRkpgdpRILLVQAVFG 87

                         90
                 ....*....|....*...
gi 446562359 135 PEHQAVINDIKNgLEKRI 152
Cdd:PRK12654  88 SDPVSVLADIAD-MEERL 104
PRK08382 PRK08382
putative monovalent cation/H+ antiporter subunit E; Reviewed
 8-130 5.40e-08

putative monovalent cation/H+ antiporter subunit E; Reviewed


Pssm-ID: 169415  Cd Length: 201  Bit Score: 49.79  E-value: 5.40e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446562359   8 LFLATAWMLLNGDYSSLQFLLGFVVGfwALRLSQPFGLKTTYFRRFRAITTLILYFI------YEMIVSVARVAWDVVTP 81
Cdd:PRK08382  40 LILLAFWVIISGDLSPRGLILGALTT--LIIASYMRDFLTEDIRRSGHLLWKILYFAliylpqYLIIMAFRLLESNLKVA 117

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 446562359  82 KHLS----DPDIVYVPLDARSDLEITLLANMVSLTPGTLSLDVSE--DRQYLIVH 130
Cdd:PRK08382 118 KHVIfmdiNPGIVKIKTDLHSDTGITILANSITLTPGTLTLDVVKklGETYLYVH 172
PRK12652 PRK12652
monovalent cation/H+ antiporter subunit E;
60-132 5.25e-07

monovalent cation/H+ antiporter subunit E;


Pssm-ID: 237160 [Multi-domain]  Cd Length: 357  Bit Score: 47.82  E-value: 5.25e-07
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446562359  60 ILYFIYEMIVSVARVAWDVVTPKHLSDPDIVYVPLDARSDLEITLLANMVSLTPGTLSLDVseDRQYLIVHAM 132
Cdd:PRK12652 231 VPYLLWEIVKANVAIAYVILHPSLPIDPTMVRVRAAVRSGLPLTTLANSITLTPGTLTVDV--DDRHLLVHSL 301
PRK06279 PRK06279
putative monovalent cation/H+ antiporter subunit E; Reviewed
 60-132 2.21e-04

putative monovalent cation/H+ antiporter subunit E; Reviewed


Pssm-ID: 180506 [Multi-domain]  Cd Length: 100  Bit Score: 38.49  E-value: 2.21e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446562359  60 ILYFIYEMIVSVARVAWDVVTPKhlSDPDIVYVPLDARSDLEITLLANMVSLTPGTLSLDVSEDRQYLIVHAM 132
Cdd:PRK06279  10 LIVLIKAIIEAWIDVVKRSLNGK--IDPEVIEIETEINRPVGQVLLANSITLTPGTLTIDLDSEERILKVASI 80
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH