|
Name |
Accession |
Description |
Interval |
E-value |
| GlnQ |
COG1126 |
ABC-type polar amino acid transport system, ATPase component [Amino acid transport and ... |
1-239 |
9.45e-163 |
|
ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 440743 [Multi-domain] Cd Length: 239 Bit Score: 449.44 E-value: 9.45e-163
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 1 MITLKNVSKWYGHFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVNDKKTDLAKLRSRVG 80
Cdd:COG1126 1 MIEIENLHKSFGDLEVLKGISLDVEKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTITVDGEDLTDSKKDINKLRRKVG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 81 MVFQHFELFPHLSIIENLTLAQVKVLKRNKAPAREKALKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMDPIAMLF 160
Cdd:COG1126 81 MVFQQFNLFPHLTVLENVTLAPIKVKKMSKAEAEERAMELLERVGLADKADAYPAQLSGGQQQRVAIARALAMEPKVMLF 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446554041 161 DEPTSALDPEMINEVLDVMVELANEGMTMMVVTHEMGFARKVANRVIFMDEGKIIEDSPKDAFFDNPKSDRAKDFLAKI 239
Cdd:COG1126 161 DEPTSALDPELVGEVLDVMRDLAKEGMTMVVVTHEMGFAREVADRVVFMDGGRIVEEGPPEEFFENPQHERTRAFLSKV 239
|
|
| ABC_HisP_GlnQ |
cd03262 |
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ... |
2-214 |
1.23e-131 |
|
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ATP-binding components of the bacterial periplasmic histidine and glutamine permeases, respectively. Histidine permease is a multi-subunit complex containing the HisQ and HisM integral membrane subunits and two copies of HisP. HisP has properties intermediate between those of integral and peripheral membrane proteins and is accessible from both sides of the membrane, presumably by its interaction with HisQ and HisM. The two HisP subunits form a homodimer within the complex. The domain structure of the amino acid uptake systems is typical for prokaryotic extracellular solute binding protein-dependent uptake systems. All of the amino acid uptake systems also have at least one, and in a few cases, two extracellular solute binding proteins located in the periplasm of Gram-negative bacteria, or attached to the cell membrane of Gram-positive bacteria. The best-studied member of the PAAT (polar amino acid transport) family is the HisJQMP system of S. typhimurium, where HisJ is the extracellular solute binding proteins and HisP is the ABC protein.
Pssm-ID: 213229 [Multi-domain] Cd Length: 213 Bit Score: 369.94 E-value: 1.23e-131
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 2 ITLKNVSKWYGHFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVNDKKTDLAKLRSRVGM 81
Cdd:cd03262 1 IEIKNLHKSFGDFHVLKGIDLTVKKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTIIIDGLKLTDDKKNINELRQKVGM 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 82 VFQHFELFPHLSIIENLTLAQVKVLKRNKAPAREKALKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMDPIAMLFD 161
Cdd:cd03262 81 VFQQFNLFPHLTVLENITLAPIKVKGMSKAEAEERALELLEKVGLADKADAYPAQLSGGQQQRVAIARALAMNPKVMLFD 160
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 446554041 162 EPTSALDPEMINEVLDVMVELANEGMTMMVVTHEMGFARKVANRVIFMDEGKI 214
Cdd:cd03262 161 EPTSALDPELVGEVLDVMKDLAEEGMTMVVVTHEMGFAREVADRVIFMDDGRI 213
|
|
| glnQ |
PRK09493 |
glutamine ABC transporter ATP-binding protein GlnQ; |
1-236 |
2.34e-110 |
|
glutamine ABC transporter ATP-binding protein GlnQ;
Pssm-ID: 181906 [Multi-domain] Cd Length: 240 Bit Score: 317.03 E-value: 2.34e-110
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 1 MITLKNVSKWYGHFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVNDKKTDLAKLRSRVG 80
Cdd:PRK09493 1 MIEFKNVSKHFGPTQVLHNIDLNIDQGEVVVIIGPSGSGKSTLLRCINKLEEITSGDLIVDGLKVNDPKVDERLIRQEAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 81 MVFQHFELFPHLSIIENLTLAQVKVLKRNKAPAREKALKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMDPIAMLF 160
Cdd:PRK09493 81 MVFQQFYLFPHLTALENVMFGPLRVRGASKEEAEKQARELLAKVGLAERAHHYPSELSGGQQQRVAIARALAVKPKLMLF 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446554041 161 DEPTSALDPEMINEVLDVMVELANEGMTMMVVTHEMGFARKVANRVIFMDEGKIIEDSPKDAFFDNPKSDRAKDFL 236
Cdd:PRK09493 161 DEPTSALDPELRHEVLKVMQDLAEEGMTMVIVTHEIGFAEKVASRLIFIDKGRIAEDGDPQVLIKNPPSQRLQEFL 236
|
|
| HisP |
COG4598 |
ABC-type histidine transport system, ATPase component [Amino acid transport and metabolism]; |
34-241 |
2.09e-107 |
|
ABC-type histidine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443652 [Multi-domain] Cd Length: 259 Bit Score: 310.19 E-value: 2.09e-107
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEPVQQGEITVDG------------IVVNDKKTdLAKLRSRVGMVFQHFELFPHLSIIENLTLA 101
Cdd:COG4598 41 GSSGSGKSTFLRCINLLETPDSGEIRVGGeeirlkpdrdgeLVPADRRQ-LQRIRTRLGMVFQSFNLWSHMTVLENVIEA 119
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 102 QVKVLKRNKAPAREKALKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLDVMVE 181
Cdd:COG4598 120 PVHVLGRPKAEAIERAEALLAKVGLADKRDAYPAHLSGGQQQRAAIARALAMEPEVMLFDEPTSALDPELVGEVLKVMRD 199
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 182 LANEGMTMMVVTHEMGFARKVANRVIFMDEGKIIEDSPKDAFFDNPKSDRAKDFLAKILH 241
Cdd:COG4598 200 LAEEGRTMLVVTHEMGFARDVSSHVVFLHQGRIEEQGPPAEVFGNPKSERLRQFLSSSLK 259
|
|
| artP |
PRK11124 |
arginine transporter ATP-binding subunit; Provisional |
2-237 |
2.72e-89 |
|
arginine transporter ATP-binding subunit; Provisional
Pssm-ID: 182980 [Multi-domain] Cd Length: 242 Bit Score: 263.80 E-value: 2.72e-89
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 2 ITLKNVSKWYGHFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVNDKKT----DLAKLRS 77
Cdd:PRK11124 3 IQLNGINCFYGAHQALFDITLDCPQGETLVLLGPSGAGKSSLLRVLNLLEMPRSGTLNIAGNHFDFSKTpsdkAIRELRR 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 78 RVGMVFQHFELFPHLSIIENLTLAQVKVLKRNKAPAREKALKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMDPIA 157
Cdd:PRK11124 83 NVGMVFQQYNLWPHLTVQQNLIEAPCRVLGLSKDQALARAEKLLERLRLKPYADRFPLHLSGGQQQRVAIARALMMEPQV 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 158 MLFDEPTSALDPEMINEVLDVMVELANEGMTMMVVTHEMGFARKVANRVIFMDEGKIIEDSPKDAfFDNPKSDRAKDFLA 237
Cdd:PRK11124 163 LLFDEPTAALDPEITAQIVSIIRELAETGITQVIVTHEVEVARKTASRVVYMENGHIVEQGDASC-FTQPQTEAFKNYLS 241
|
|
| ArtP |
COG4161 |
ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism]; |
2-237 |
6.33e-88 |
|
ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443326 [Multi-domain] Cd Length: 242 Bit Score: 260.33 E-value: 6.33e-88
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 2 ITLKNVSKWYGHFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVNDKKTDLAK----LRS 77
Cdd:COG4161 3 IQLKNINCFYGSHQALFDINLECPSGETLVLLGPSGAGKSSLLRVLNLLETPDSGQLNIAGHQFDFSQKPSEKairlLRQ 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 78 RVGMVFQHFELFPHLSIIENLTLAQVKVLKRNKAPAREKALKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMDPIA 157
Cdd:COG4161 83 KVGMVFQQYNLWPHLTVMENLIEAPCKVLGLSKEQAREKAMKLLARLRLTDKADRFPLHLSGGQQQRVAIARALMMEPQV 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 158 MLFDEPTSALDPEMINEVLDVMVELANEGMTMMVVTHEMGFARKVANRVIFMDEGKIIEDSPKDAfFDNPKSDRAKDFLA 237
Cdd:COG4161 163 LLFDEPTAALDPEITAQVVEIIRELSQTGITQVIVTHEVEFARKVASQVVYMEKGRIIEQGDASH-FTQPQTEAFAHYLS 241
|
|
| ectoine_ehuA |
TIGR03005 |
ectoine/hydroxyectoine ABC transporter, ATP-binding protein; Members of this family are the ... |
2-240 |
3.42e-85 |
|
ectoine/hydroxyectoine ABC transporter, ATP-binding protein; Members of this family are the ATP-binding protein of a conserved four gene ABC transporter operon found next to ectoine unilization operons and ectoine biosynthesis operons. Ectoine is a compatible solute that protects enzymes from high osmolarity. It is released by some species in response to hypoosmotic shock, and it is taken up by a number of bacteria as a compatible solute or for consumption. This family shows strong sequence similiarity to a number of amino acid ABC transporter ATP-binding proteins.
Pssm-ID: 132050 [Multi-domain] Cd Length: 252 Bit Score: 253.60 E-value: 3.42e-85
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 2 ITLKNVSKWYGHFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQQGEITVDG------------IVVNDKK 69
Cdd:TIGR03005 1 VRFSDVTKRFGILTVLDGLNFSVAAGEKVALIGPSGSGKSTILRILMTLEPIDEGQIQVEGeqlyhmpgrngpLVPADEK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 70 tDLAKLRSRVGMVFQHFELFPHLSIIENLTLAQVKVLKRNKAPAREKALKLLERVGLSAHANKFPAQLSGGQQQRVAIAR 149
Cdd:TIGR03005 81 -HLRQMRNKIGMVFQSFNLFPHKTVLDNVTEAPVLVLGMARAEAEKRAMELLDMVGLADKADHMPAQLSGGQQQRVAIAR 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 150 ALCMDPIAMLFDEPTSALDPEMINEVLDVMVELANE-GMTMMVVTHEMGFARKVANRVIFMDEGKIIEDSPKDAFFDNPK 228
Cdd:TIGR03005 160 ALAMRPKVMLFDEVTSALDPELVGEVLNVIRRLASEhDLTMLLVTHEMGFAREFADRVCFFDKGRIVEQGKPDEIFRQPK 239
|
250
....*....|..
gi 446554041 229 SDRAKDFLAKIL 240
Cdd:TIGR03005 240 EERTREFLSKVI 251
|
|
| PRK11264 |
PRK11264 |
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional |
1-240 |
6.44e-83 |
|
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional
Pssm-ID: 183063 [Multi-domain] Cd Length: 250 Bit Score: 247.74 E-value: 6.44e-83
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 1 MITLKNVSKWYGHFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEP-----VQQGEITVDG-IVVNDKKTDLAK 74
Cdd:PRK11264 3 AIEVKNLVKKFHGQTVLHGIDLEVKPGEVVAIIGPSGSGKTTLLRCINLLEQpeagtIRVGDITIDTaRSLSQQKGLIRQ 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 75 LRSRVGMVFQHFELFPHLSIIENLTLAQVKVLKRNKAPAREKALKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMD 154
Cdd:PRK11264 83 LRQHVGFVFQNFNLFPHRTVLENIIEGPVIVKGEPKEEATARARELLAKVGLAGKETSYPRRLSGGQQQRVAIARALAMR 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 155 PIAMLFDEPTSALDPEMINEVLDVMVELANEGMTMMVVTHEMGFARKVANRVIFMDEGKIIEDSPKDAFFDNPKSDRAKD 234
Cdd:PRK11264 163 PEVILFDEPTSALDPELVGEVLNTIRQLAQEKRTMVIVTHEMSFARDVADRAIFMDQGRIVEQGPAKALFADPQQPRTRQ 242
|
....*.
gi 446554041 235 FLAKIL 240
Cdd:PRK11264 243 FLEKFL 248
|
|
| PRK10619 |
PRK10619 |
histidine ABC transporter ATP-binding protein HisP; |
9-240 |
5.98e-79 |
|
histidine ABC transporter ATP-binding protein HisP;
Pssm-ID: 182592 [Multi-domain] Cd Length: 257 Bit Score: 237.94 E-value: 5.98e-79
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 9 KWYGHFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQQGEITVDG---IVVNDK--------KTDLAKLRS 77
Cdd:PRK10619 13 KRYGEHEVLKGVSLQANAGDVISIIGSSGSGKSTFLRCINFLEKPSEGSIVVNGqtiNLVRDKdgqlkvadKNQLRLLRT 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 78 RVGMVFQHFELFPHLSIIENLTLAQVKVLKRNKAPAREKALKLLERVGLSAHAN-KFPAQLSGGQQQRVAIARALCMDPI 156
Cdd:PRK10619 93 RLTMVFQHFNLWSHMTVLENVMEAPIQVLGLSKQEARERAVKYLAKVGIDERAQgKYPVHLSGGQQQRVSIARALAMEPE 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 157 AMLFDEPTSALDPEMINEVLDVMVELANEGMTMMVVTHEMGFARKVANRVIFMDEGKIIEDSPKDAFFDNPKSDRAKDFL 236
Cdd:PRK10619 173 VLLFDEPTSALDPELVGEVLRIMQQLAEEGKTMVVVTHEMGFARHVSSHVIFLHQGKIEEEGAPEQLFGNPQSPRLQQFL 252
|
....
gi 446554041 237 AKIL 240
Cdd:PRK10619 253 KGSL 256
|
|
| AbcC |
COG1135 |
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism]; |
1-241 |
7.78e-78 |
|
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 440750 [Multi-domain] Cd Length: 339 Bit Score: 237.67 E-value: 7.78e-78
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 1 MITLKNVSKWY----GHFQVLTDCStevkkgevvvvcGPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVND-KKTDLAKL 75
Cdd:COG1135 1 MIELENLSKTFptkgGPVTALDDVSltiekgeifgiiGYSGAGKSTLIRCINLLERPTSGSVLVDGVDLTAlSERELRAA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 76 RSRVGMVFQHFELFPHLSIIENLTLAqVKVLKRNKAPAREKALKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMDP 155
Cdd:COG1135 81 RRKIGMIFQHFNLLSSRTVAENVALP-LEIAGVPKAEIRKRVAELLELVGLSDKADAYPSQLSGGQKQRVGIARALANNP 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 156 IAMLFDEPTSALDPEMINEVLDVMVELaNE--GMTMMVVTHEMGFARKVANRVIFMDEGKIIEDSPKDAFFDNPKSDRAK 233
Cdd:COG1135 160 KVLLCDEATSALDPETTRSILDLLKDI-NRelGLTIVLITHEMDVVRRICDRVAVLENGRIVEQGPVLDVFANPQSELTR 238
|
....*...
gi 446554041 234 DFLAKILH 241
Cdd:COG1135 239 RFLPTVLN 246
|
|
| LolD |
COG1136 |
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis]; |
1-219 |
2.96e-74 |
|
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440751 [Multi-domain] Cd Length: 227 Bit Score: 224.92 E-value: 2.96e-74
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 1 MITLKNVSKWYG----HFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVND-KKTDLAKL 75
Cdd:COG1136 4 LLELRNLTKSYGtgegEVTALRGVSLSIEAGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVLIDGQDISSlSERELARL 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 76 RSR-VGMVFQHFELFPHLSIIENLTLAQVkVLKRNKAPAREKALKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMD 154
Cdd:COG1136 84 RRRhIGFVFQFFNLLPELTALENVALPLL-LAGVSRKERRERARELLERVGLGDRLDHRPSQLSGGQQQRVAIARALVNR 162
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446554041 155 PIAMLFDEPTSALDPEMINEVLDVMVELANE-GMTMMVVTHEMGFARKvANRVIFMDEGKIIEDSP 219
Cdd:COG1136 163 PKLILADEPTGNLDSKTGEEVLELLRELNRElGTTIVMVTHDPELAAR-ADRVIRLRDGRIVSDER 227
|
|
| ABC_MJ0796_LolCDE_FtsE |
cd03255 |
ATP-binding cassette domain of the transporters involved in export of lipoprotein and ... |
2-214 |
1.98e-72 |
|
ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and Cell division ATP-binding protein FtsE; This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.
Pssm-ID: 213222 [Multi-domain] Cd Length: 218 Bit Score: 220.05 E-value: 1.98e-72
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 2 ITLKNVSKWYG----HFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVNDKK-TDLAKLR 76
Cdd:cd03255 1 IELKNLSKTYGgggeKVQALKGVSLSIEKGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVRVDGTDISKLSeKELAAFR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 77 SR-VGMVFQHFELFPHLSIIENLTLAQVkVLKRNKAPAREKALKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMDP 155
Cdd:cd03255 81 RRhIGFVFQSFNLLPDLTALENVELPLL-LAGVPKKERRERAEELLERVGLGDRLNHYPSELSGGQQQRVAIARALANDP 159
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 156 IAMLFDEPTSALDPEMINEVLDVMVELANE-GMTMMVVTHEMGFARKvANRVIFMDEGKI 214
Cdd:cd03255 160 KIILADEPTGNLDSETGKEVMELLRELNKEaGTTIVVVTHDPELAEY-ADRIIELRDGKI 218
|
|
| 3a0107s01c2 |
TIGR00972 |
phosphate ABC transporter, ATP-binding protein; This model represents the ATP-binding protein ... |
2-238 |
7.81e-72 |
|
phosphate ABC transporter, ATP-binding protein; This model represents the ATP-binding protein of a family of ABC transporters for inorganic phosphate. In the model species Escherichia coli, a constitutive transporter for inorganic phosphate, with low affinity, is also present. The high affinity transporter that includes this polypeptide is induced when extracellular phosphate concentrations are low. The proteins most similar to the members of this family but not included appear to be amino acid transporters. [Transport and binding proteins, Anions]
Pssm-ID: 273372 [Multi-domain] Cd Length: 247 Bit Score: 219.47 E-value: 7.81e-72
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 2 ITLKNVSKWYGHFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPV-----QQGEITVDGIVVNDKKTDLAKLR 76
Cdd:TIGR00972 2 IEIENLNLFYGEKEALKNINLDIPKNQVTALIGPSGCGKSTLLRSLNRMNDLvpgvrIEGKVLFDGQDIYDKKIDVVELR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 77 SRVGMVFQHFELFPhLSIIENLTLAqVKVLK-RNKAPAREKALKLLERVGL------SAHANKFpaQLSGGQQQRVAIAR 149
Cdd:TIGR00972 82 RRVGMVFQKPNPFP-MSIYDNIAYG-PRLHGiKDKKELDEIVEESLKKAALwdevkdRLHDSAL--GLSGGQQQRLCIAR 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 150 ALCMDPIAMLFDEPTSALDPEMINEVLDVMVELAnEGMTMMVVTHEMGFARKVANRVIFMDEGKIIEDSPKDAFFDNPKS 229
Cdd:TIGR00972 158 ALAVEPEVLLLDEPTSALDPIATGKIEELIQELK-KKYTIVIVTHNMQQAARISDRTAFFYDGELVEYGPTEQIFTNPKE 236
|
....*....
gi 446554041 230 DRAKDFLAK 238
Cdd:TIGR00972 237 KRTEDYISG 245
|
|
| FtsE |
COG2884 |
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning]; |
1-220 |
7.82e-72 |
|
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442130 [Multi-domain] Cd Length: 223 Bit Score: 218.38 E-value: 7.82e-72
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 1 MITLKNVSKWYGH-FQVLTDCS-----------TevkkgevvvvcGPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVND- 67
Cdd:COG2884 1 MIRFENVSKRYPGgREALSDVSleiekgefvflT-----------GPSGAGKSTLLKLLYGEERPTSGQVLVNGQDLSRl 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 68 KKTDLAKLRSRVGMVFQHFELFPHLSIIENLTLAQvKVLKRNKAPAREKALKLLERVGLSAHANKFPAQLSGGQQQRVAI 147
Cdd:COG2884 70 KRREIPYLRRRIGVVFQDFRLLPDRTVYENVALPL-RVTGKSRKEIRRRVREVLDLVGLSDKAKALPHELSGGEQQRVAI 148
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446554041 148 ARALCMDPIAMLFDEPTSALDPEMINEVLDVMVELANEGMTMMVVTHEMGFARKVANRVIFMDEGKIIEDSPK 220
Cdd:COG2884 149 ARALVNRPELLLADEPTGNLDPETSWEIMELLEEINRRGTTVLIATHDLELVDRMPKRVLELEDGRLVRDEAR 221
|
|
| ABC_MetN_methionine_transporter |
cd03258 |
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ... |
1-228 |
5.96e-71 |
|
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ABC-type transporter encoded by metN of the metNPQ operon in Bacillus subtilis that is involved in methionine transport. Other members of this system include the MetP permease and the MetQ substrate binding protein. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213225 [Multi-domain] Cd Length: 233 Bit Score: 216.68 E-value: 5.96e-71
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 1 MITLKNVSKWYGH----FQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVND-KKTDLAKL 75
Cdd:cd03258 1 MIELKNVSKVFGDtggkVTALKDVSLSVPKGEIFGIIGRSGAGKSTLIRCINGLERPTSGSVLVDGTDLTLlSGKELRKA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 76 RSRVGMVFQHFELFPHLSIIENLTLAqVKVLKRNKAPAREKALKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMDP 155
Cdd:cd03258 81 RRRIGMIFQHFNLLSSRTVFENVALP-LEIAGVPKAEIEERVLELLELVGLEDKADAYPAQLSGGQKQRVGIARALANNP 159
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446554041 156 IAMLFDEPTSALDPEMINEVLDVMVELANE-GMTMMVVTHEMGFARKVANRVIFMDEGKIIEDSPKDAFFDNPK 228
Cdd:cd03258 160 KVLLCDEATSALDPETTQSILALLRDINRElGLTIVLITHEMEVVKRICDRVAVMEKGEVVEEGTVEEVFANPQ 233
|
|
| PhnC |
COG3638 |
ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and ... |
1-239 |
1.90e-69 |
|
ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 442855 [Multi-domain] Cd Length: 249 Bit Score: 213.38 E-value: 1.90e-69
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 1 MITLKNVSKWY-GHFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQQGEITVDGI-VVNDKKTDLAKLRSR 78
Cdd:COG3638 2 MLELRNLSKRYpGGTPALDDVSLEIERGEFVALIGPSGAGKSTLLRCLNGLVEPTSGEILVDGQdVTALRGRALRRLRRR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 79 VGMVFQHFELFPHLSIIEN-LT--LAQVKVLK--RNKAPA--REKALKLLERVGLSAHANKFPAQLSGGQQQRVAIARAL 151
Cdd:COG3638 82 IGMIFQQFNLVPRLSVLTNvLAgrLGRTSTWRslLGLFPPedRERALEALERVGLADKAYQRADQLSGGQQQRVAIARAL 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 152 CMDPIAMLFDEPTSALDPEMINEVLDVMVELANE-GMTMMVVTHEMGFARKVANRVIFMDEGKIIedspkdafFDNPKSD 230
Cdd:COG3638 162 VQEPKLILADEPVASLDPKTARQVMDLLRRIAREdGITVVVNLHQVDLARRYADRIIGLRDGRVV--------FDGPPAE 233
|
....*....
gi 446554041 231 RAKDFLAKI 239
Cdd:COG3638 234 LTDAVLREI 242
|
|
| MlaF |
COG1127 |
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall ... |
1-236 |
1.21e-68 |
|
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440744 [Multi-domain] Cd Length: 241 Bit Score: 210.99 E-value: 1.21e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 1 MITLKNVSKWYGHFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVND-KKTDLAKLRSRV 79
Cdd:COG1127 5 MIEVRNLTKSFGDRVVLDGVSLDVPRGEILAIIGGSGSGKSVLLKLIIGLLRPDSGEILVDGQDITGlSEKELYELRRRI 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 80 GMVFQHFELFPHLSIIENLTLAQVKVLKRNKAPAREKALKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMDPIAML 159
Cdd:COG1127 85 GMLFQGGALFDSLTVFENVAFPLREHTDLSEAEIRELVLEKLELVGLPGAADKMPSELSGGMRKRVALARALALDPEILL 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 160 FDEPTSALDPEMINEVLDVMVELANE-GMTMMVVTHEMGFARKVANRVIFMDEGKIIEDSPKDAFF--DNPksdRAKDFL 236
Cdd:COG1127 165 YDEPTAGLDPITSAVIDELIRELRDElGLTSVVVTHDLDSAFAIADRVAVLADGKIIAEGTPEELLasDDP---WVRQFL 241
|
|
| ABC_Carb_Solutes_like |
cd03259 |
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is ... |
2-216 |
1.86e-68 |
|
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is comprised of proteins involved in the transport of apparently unrelated solutes and proteins specific for di- and oligosaccharides and polyols. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213226 [Multi-domain] Cd Length: 213 Bit Score: 209.68 E-value: 1.86e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 2 ITLKNVSKWYGHFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVndkkTDLAKLRSRVGM 81
Cdd:cd03259 1 LELKGLSKTYGSVRALDDLSLTVEPGEFLALLGPSGCGKTTLLRLIAGLERPDSGEILIDGRDV----TGVPPERRNIGM 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 82 VFQHFELFPHLSIIENLTLAqVKVLKRNKAPAREKALKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMDPIAMLFD 161
Cdd:cd03259 77 VFQDYALFPHLTVAENIAFG-LKLRGVPKAEIRARVRELLELVGLEGLLNRYPHELSGGQQQRVALARALAREPSLLLLD 155
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 446554041 162 EPTSALDPEMINEVLDVMVEL-ANEGMTMMVVTHEMGFARKVANRVIFMDEGKIIE 216
Cdd:cd03259 156 EPLSALDAKLREELREELKELqRELGITTIYVTHDQEEALALADRIAVMNEGRIVQ 211
|
|
| ABC_Class3 |
cd03229 |
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is ... |
2-213 |
3.69e-68 |
|
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is comprised of all BPD (Binding Protein Dependent) systems that are largely represented in archaea and eubacteria and are primarily involved in scavenging solutes from the environment. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213196 [Multi-domain] Cd Length: 178 Bit Score: 207.81 E-value: 3.69e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 2 ITLKNVSKWYGHFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVNDKKTDLAKLRSRVGM 81
Cdd:cd03229 1 LELKNVSKRYGQKTVLNDVSLNIEAGEIVALLGPSGSGKSTLLRCIAGLEEPDSGSILIDGEDLTDLEDELPPLRRRIGM 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 82 VFQHFELFPHLSIIENLTLAqvkvlkrnkaparekalkllervglsahankfpaqLSGGQQQRVAIARALCMDPIAMLFD 161
Cdd:cd03229 81 VFQDFALFPHLTVLENIALG-----------------------------------LSGGQQQRVALARALAMDPDVLLLD 125
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 446554041 162 EPTSALDPEMINEVLDVMVEL-ANEGMTMMVVTHEMGFARKVANRVIFMDEGK 213
Cdd:cd03229 126 EPTSALDPITRREVRALLKSLqAQLGITVVLVTHDLDEAARLADRVVVLRDGK 178
|
|
| GsiA |
COG1123 |
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ... |
34-237 |
5.38e-68 |
|
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440740 [Multi-domain] Cd Length: 514 Bit Score: 217.85 E-value: 5.38e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVND-KKTDLAKLRSRVGMVFQHFE--LFPHLSIIENLTLAQVKVLKRNK 110
Cdd:COG1123 298 GESGSGKSTLARLLLGLLRPTSGSILFDGKDLTKlSRRSLRELRRRVQMVFQDPYssLNPRMTVGDIIAEPLRLHGLLSR 377
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 111 APAREKALKLLERVGLSA-HANKFPAQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLDVMVELANE-GMT 188
Cdd:COG1123 378 AERRERVAELLERVGLPPdLADRYPHELSGGQRQRVAIARALALEPKLLILDEPTSALDVSVQAQILNLLRDLQRElGLT 457
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 446554041 189 MMVVTHEMGFARKVANRVIFMDEGKIIEDSPKDAFFDNPKSDRAKDFLA 237
Cdd:COG1123 458 YLFISHDLAVVRYIADRVAVMYDGRIVEDGPTEEVFANPQHPYTRALLA 506
|
|
| ABC_PhnC_transporter |
cd03256 |
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; ... |
2-223 |
1.22e-66 |
|
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Phosphonates are a class of organophosphorus compounds characterized by a chemically stable carbon-to-phosphorus (C-P) bond. Phosphonates are widespread among naturally occurring compounds in all kingdoms of wildlife, but only prokaryotic microorganisms are able to cleave this bond. Certain bacteria such as E. coli can use alkylphosphonates as a phosphorus source. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213223 [Multi-domain] Cd Length: 241 Bit Score: 205.88 E-value: 1.22e-66
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 2 ITLKNVSKWYGH-FQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVN-DKKTDLAKLRSRV 79
Cdd:cd03256 1 IEVENLSKTYPNgKKALKDVSLSINPGEFVALIGPSGAGKSTLLRCLNGLVEPTSGSVLIDGTDINkLKGKALRQLRRQI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 80 GMVFQHFELFPHLSIIENL------TLAQVKVLKRNKAPA-REKALKLLERVGLSAHANKFPAQLSGGQQQRVAIARALC 152
Cdd:cd03256 81 GMIFQQFNLIERLSVLENVlsgrlgRRSTWRSLFGLFPKEeKQRALAALERVGLLDKAYQRADQLSGGQQQRVAIARALM 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446554041 153 MDPIAMLFDEPTSALDPEMINEVLDVMVELANE-GMTMMVVTHEMGFARKVANRVIFMDEGKIIEDSPKDAF 223
Cdd:cd03256 161 QQPKLILADEPVASLDPASSRQVMDLLKRINREeGITVIVSLHQVDLAREYADRIVGLKDGRIVFDGPPAEL 232
|
|
| CcmA |
COG1131 |
ABC-type multidrug transport system, ATPase component [Defense mechanisms]; |
2-223 |
9.45e-66 |
|
ABC-type multidrug transport system, ATPase component [Defense mechanisms];
Pssm-ID: 440746 [Multi-domain] Cd Length: 236 Bit Score: 203.37 E-value: 9.45e-66
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 2 ITLKNVSKWYGHFQVLTDCStevkkgevvvvcGPSGSGKSTLIKTVNGLEPVQQGEITVDGIvvnDKKTDLAKLRSRVGM 81
Cdd:COG1131 1 IEVRGLTKRYGDKTALDGVSltvepgeifgllGPNGAGKTTTIRMLLGLLRPTSGEVRVLGE---DVARDPAEVRRRIGY 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 82 VFQHFELFPHLSIIENLTLAQvKVLKRNKAPAREKALKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMDPIAMLFD 161
Cdd:COG1131 78 VPQEPALYPDLTVRENLRFFA-RLYGLPRKEARERIDELLELFGLTDAADRKVGTLSGGMKQRLGLALALLHDPELLILD 156
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446554041 162 EPTSALDPEMINEVLDVMVELANEGMTMMVVTHEMGFARKVANRVIFMDEGKIIEDSPKDAF 223
Cdd:COG1131 157 EPTSGLDPEARRELWELLRELAAEGKTVLLSTHYLEEAERLCDRVAIIDKGRIVADGTPDEL 218
|
|
| PotA |
COG3842 |
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport ... |
1-236 |
1.01e-65 |
|
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443052 [Multi-domain] Cd Length: 353 Bit Score: 207.26 E-value: 1.01e-65
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 1 MITLKNVSKWYGHFQVLTDCStevkkgevvvvcGPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVndkkTDLAKLRSRVG 80
Cdd:COG3842 5 ALELENVSKRYGDVTALDDVSlsiepgefvallGPSGCGKTTLLRMIAGFETPDSGRILLDGRDV----TGLPPEKRNVG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 81 MVFQHFELFPHLSIIENLT--LaqvKVLKRNKAPAREKALKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMDPIAM 158
Cdd:COG3842 81 MVFQDYALFPHLTVAENVAfgL---RMRGVPKAEIRARVAELLELVGLEGLADRYPHQLSGGQQQRVALARALAPEPRVL 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 159 LFDEPTSALDP----EMINEVLDVMVELaneGMTMMVVTH--EMGFArkVANRVIFMDEGKIIE-DSPKDAfFDNPKSDR 231
Cdd:COG3842 158 LLDEPLSALDAklreEMREELRRLQREL---GITFIYVTHdqEEALA--LADRIAVMNDGRIEQvGTPEEI-YERPATRF 231
|
....*
gi 446554041 232 AKDFL 236
Cdd:COG3842 232 VADFI 236
|
|
| DppF |
COG1124 |
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ... |
1-240 |
2.36e-65 |
|
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];
Pssm-ID: 440741 [Multi-domain] Cd Length: 248 Bit Score: 203.11 E-value: 2.36e-65
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 1 MITLKNVSKWYG----HFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVndKKTDLAKLR 76
Cdd:COG1124 1 MLEVRNLSVSYGqggrRVPVLKDVSLEVAPGESFGLVGESGSGKSTLLRALAGLERPWSGEVTFDGRPV--TRRRRKAFR 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 77 SRVGMVFQHfelfPHLSIIENLTLAQV-----KVLKRNKAPARekALKLLERVGL-SAHANKFPAQLSGGQQQRVAIARA 150
Cdd:COG1124 79 RRVQMVFQD----PYASLHPRHTVDRIlaeplRIHGLPDREER--IAELLEQVGLpPSFLDRYPHQLSGGQRQRVAIARA 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 151 LCMDPIAMLFDEPTSALDPEMINEVLDVMVELANE-GMTMMVVTHEMGFARKVANRVIFMDEGKIIEDSPKDAFFDNPKS 229
Cdd:COG1124 153 LILEPELLLLDEPTSALDVSVQAEILNLLKDLREErGLTYLFVSHDLAVVAHLCDRVAVMQNGRIVEELTVADLLAGPKH 232
|
250
....*....|.
gi 446554041 230 DRAKDFLAKIL 240
Cdd:COG1124 233 PYTRELLAASL 243
|
|
| TauB |
COG1116 |
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion ... |
1-217 |
3.74e-64 |
|
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440733 [Multi-domain] Cd Length: 260 Bit Score: 200.32 E-value: 3.74e-64
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 1 MITLKNVSKWY----GHFQVLTDCS--------TevkkgevvvvC--GPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVn 66
Cdd:COG1116 7 ALELRGVSKRFptggGGVTALDDVSltvaagefV----------AlvGPSGCGKSTLLRLIAGLEKPTSGEVLVDGKPV- 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 67 dkktdlAKLRSRVGMVFQHFELFPHLSIIENLTLAqVKVLKRNKAPAREKALKLLERVGLSAHANKFPAQLSGGQQQRVA 146
Cdd:COG1116 76 ------TGPGPDRGVVFQEPALLPWLTVLDNVALG-LELRGVPKAERRERARELLELVGLAGFEDAYPHQLSGGMRQRVA 148
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446554041 147 IARALCMDPIAMLFDEPTSALDP----EMINEVLDVmveLANEGMTMMVVTHEMGFARKVANRVIFMDE--GKIIED 217
Cdd:COG1116 149 IARALANDPEVLLMDEPFGALDAltreRLQDELLRL---WQETGKTVLFVTHDVDEAVFLADRVVVLSArpGRIVEE 222
|
|
| metN |
PRK11153 |
DL-methionine transporter ATP-binding subunit; Provisional |
1-241 |
3.87e-64 |
|
DL-methionine transporter ATP-binding subunit; Provisional
Pssm-ID: 236863 [Multi-domain] Cd Length: 343 Bit Score: 203.11 E-value: 3.87e-64
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 1 MITLKNVSKWY----GHFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQQGEITVDGI-VVNDKKTDLAKL 75
Cdd:PRK11153 1 MIELKNISKVFpqggRTIHALNNVSLHIPAGEIFGVIGASGAGKSTLIRCINLLERPTSGRVLVDGQdLTALSEKELRKA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 76 RSRVGMVFQHFELFPHLSIIENLTLAqVKVLKRNKAPAREKALKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMDP 155
Cdd:PRK11153 81 RRQIGMIFQHFNLLSSRTVFDNVALP-LELAGTPKAEIKARVTELLELVGLSDKADRYPAQLSGGQKQRVAIARALASNP 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 156 IAMLFDEPTSALDPEMINEVLDVMVELANE-GMTMMVVTHEMGFARKVANRVIFMDEGKIIEDSPKDAFFDNPKSDRAKD 234
Cdd:PRK11153 160 KVLLCDEATSALDPATTRSILELLKDINRElGLTIVLITHEMDVVKRICDRVAVIDAGRLVEQGTVSEVFSHPKHPLTRE 239
|
....*..
gi 446554041 235 FLAKILH 241
Cdd:PRK11153 240 FIQSTLH 246
|
|
| EcfA2 |
COG1122 |
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and ... |
34-228 |
6.59e-64 |
|
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and metabolism, General function prediction only];
Pssm-ID: 440739 [Multi-domain] Cd Length: 230 Bit Score: 198.71 E-value: 6.59e-64
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVNDKktDLAKLRSRVGMVFQHFE--LFpHLSIIENLTLAqVKVLKRNKA 111
Cdd:COG1122 34 GPNGSGKSTLLRLLNGLLKPTSGEVLVDGKDITKK--NLRELRRKVGLVFQNPDdqLF-APTVEEDVAFG-PENLGLPRE 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 112 PAREKALKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLDVMVELANEGMTMMV 191
Cdd:COG1122 110 EIRERVEEALELVGLEHLADRPPHELSGGQKQRVAIAGVLAMEPEVLVLDEPTAGLDPRGRRELLELLKRLNKEGKTVII 189
|
170 180 190
....*....|....*....|....*....|....*..
gi 446554041 192 VTHEMGFARKVANRVIFMDEGKIIEDSPKDAFFDNPK 228
Cdd:COG1122 190 VTHDLDLVAELADRVIVLDDGRIVADGTPREVFSDYE 226
|
|
| ABC_PstB_phosphate_transporter |
cd03260 |
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of ... |
2-223 |
1.40e-63 |
|
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of fundamental importance in the cell physiology of bacteria because phosphate is required as a nutrient. The Pst system of E. coli comprises four distinct subunits encoded by the pstS, pstA, pstB, and pstC genes. The PstS protein is a phosphate-binding protein located in the periplasmic space. PstA and PstC are hydrophobic and they form the transmembrane portion of the Pst system. PstB is the catalytic subunit, which couples the energy of ATP hydrolysis to the import of phosphate across cellular membranes through the Pst system, often referred as ABC-protein. PstB belongs to one of the largest superfamilies of proteins characterized by a highly conserved adenosine triphosphate (ATP) binding cassette (ABC), which is also a nucleotide binding domain (NBD).
Pssm-ID: 213227 [Multi-domain] Cd Length: 227 Bit Score: 197.79 E-value: 1.40e-63
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 2 ITLKNVSKWYGHFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQQ-----GEITVDGIVVNDKKTDLAKLR 76
Cdd:cd03260 1 IELRDLNVYYGDKHALKDISLDIPKGEITALIGPSGCGKSTLLRLLNRLNDLIPgapdeGEVLLDGKDIYDLDVDVLELR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 77 SRVGMVFQHFELFPhLSIIENLTLAQVKVLKRNKAPAREKALKLLERVGL--SAHANKFPAQLSGGQQQRVAIARALCMD 154
Cdd:cd03260 81 RRVGMVFQKPNPFP-GSIYDNVAYGLRLHGIKLKEELDERVEEALRKAALwdEVKDRLHALGLSGGQQQRLCLARALANE 159
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446554041 155 PIAMLFDEPTSALDPEMINEVLDVMVELANEgMTMMVVTHEMGFARKVANRVIFMDEGKIIEDSPKDAF 223
Cdd:cd03260 160 PEVLLLDEPTSALDPISTAKIEELIAELKKE-YTIVIVTHNMQQAARVADRTAFLLNGRLVEFGPTEQI 227
|
|
| ABC_Org_Solvent_Resistant |
cd03261 |
ATP-binding cassette transport system involved in resistance to organic solvents; ABC ... |
2-227 |
2.36e-63 |
|
ATP-binding cassette transport system involved in resistance to organic solvents; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213228 [Multi-domain] Cd Length: 235 Bit Score: 197.34 E-value: 2.36e-63
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 2 ITLKNVSKWYGHFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQQGEITVDGI-VVNDKKTDLAKLRSRVG 80
Cdd:cd03261 1 IELRGLTKSFGGRTVLKGVDLDVRRGEILAIIGPSGSGKSTLLRLIVGLLRPDSGEVLIDGEdISGLSEAELYRLRRRMG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 81 MVFQHFELFPHLSIIENLTLAQVKVLKRNKAPAREKALKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMDPIAMLF 160
Cdd:cd03261 81 MLFQSGALFDSLTVFENVAFPLREHTRLSEEEIREIVLEKLEAVGLRGAEDLYPAELSGGMKKRVALARALALDPELLLY 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 161 DEPTSALDPEMINEVLDVMVELANE-GMTMMVVTHEMGFARKVANRVIFMDEGKIIEDSPKDAFF--DNP 227
Cdd:cd03261 161 DEPTAGLDPIASGVIDDLIRSLKKElGLTSIMVTHDLDTAFAIADRIAVLYDGKIVAEGTPEELRasDDP 230
|
|
| CysA |
COG1118 |
ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and ... |
2-236 |
1.77e-62 |
|
ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440735 [Multi-domain] Cd Length: 348 Bit Score: 198.83 E-value: 1.77e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 2 ITLKNVSKWYGHFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVNdkkTDLAKLRSRVGM 81
Cdd:COG1118 3 IEVRNISKRFGSFTLLDDVSLEIASGELVALLGPSGSGKTTLLRIIAGLETPDSGRIVLNGRDLF---TNLPPRERRVGF 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 82 VFQHFELFPHLSIIENLTLAqVKVLKRNKAPAREKALKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMDPIAMLFD 161
Cdd:COG1118 80 VFQHYALFPHMTVAENIAFG-LRVRPPSKAEIRARVEELLELVQLEGLADRYPSQLSGGQRQRVALARALAVEPEVLLLD 158
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446554041 162 EPTSALD----PEMINEVLDVmveLANEGMTMMVVTHEMGFARKVANRVIFMDEGKIIEDSPKDAFFDNPKSDRAKDFL 236
Cdd:COG1118 159 EPFGALDakvrKELRRWLRRL---HDELGGTTVFVTHDQEEALELADRVVVMNQGRIEQVGTPDEVYDRPATPFVARFL 234
|
|
| ThiQ |
COG3840 |
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism]; |
1-236 |
6.87e-61 |
|
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];
Pssm-ID: 443051 [Multi-domain] Cd Length: 232 Bit Score: 191.12 E-value: 6.87e-61
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 1 MITLKNVSKWYGHFQVLTDCSTEVKKGEVVVvcGPSGSGKSTLIKTVNGLEPVQQGEITVDGivvndkkTDLAKLRS--R 78
Cdd:COG3840 1 MLRLDDLTYRYGDFPLRFDLTIAAGERVAIL--GPSGAGKSTLLNLIAGFLPPDSGRILWNG-------QDLTALPPaeR 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 79 -VGMVFQHFELFPHLSIIENLTLAQVKVLKRNkAPAREKALKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMD-PI 156
Cdd:COG3840 72 pVSMLFQENNLFPHLTVAQNIGLGLRPGLKLT-AEQRAQVEQALERVGLAGLLDRLPGQLSGGQRQRVALARCLVRKrPI 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 157 aMLFDEPTSALDPEMINEVLDVMVELANE-GMTMMVVTHEMGFARKVANRVIFMDEGKIIEDSPKDAFFDNPKSDRAKDF 235
Cdd:COG3840 151 -LLLDEPFSALDPALRQEMLDLVDELCRErGLTVLMVTHDPEDAARIADRVLLVADGRIAADGPTAALLDGEPPPALAAY 229
|
.
gi 446554041 236 L 236
Cdd:COG3840 230 L 230
|
|
| ABC_NikE_OppD_transporters |
cd03257 |
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter ... |
1-217 |
7.57e-61 |
|
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter subfamily specific for the transport of dipeptides, oligopeptides (OppD), and nickel (NikDE). The NikABCDE system of E. coli belongs to this family and is composed of the periplasmic binding protein NikA, two integral membrane components (NikB and NikC), and two ATPase (NikD and NikE). The NikABCDE transporter is synthesized under anaerobic conditions to meet the increased demand for nickel resulting from hydrogenase synthesis. The molecular mechanism of nickel uptake in many bacteria and most archaea is not known. Many other members of this ABC family are also involved in the uptake of dipeptides and oligopeptides. The oligopeptide transport system (Opp) is a five-component ABC transport composed of a membrane-anchored substrate binding proteins (SRP), OppA, two transmembrane proteins, OppB and OppC, and two ATP-binding domains, OppD and OppF.
Pssm-ID: 213224 [Multi-domain] Cd Length: 228 Bit Score: 190.79 E-value: 7.57e-61
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 1 MITLKNVSKWY----GHFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVNDKKTDLAKLR 76
Cdd:cd03257 1 LLEVKNLSVSFptggGSVKALDDVSFSIKKGETLGLVGESGSGKSTLARAILGLLKPTSGSIIFDGKDLLKLSRRLRKIR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 77 -SRVGMVFQH--FELFPHLSIIENLT-LAQVKVLKRNKAPAREKALKLLERVGLSA-HANKFPAQLSGGQQQRVAIARAL 151
Cdd:cd03257 81 rKEIQMVFQDpmSSLNPRMTIGEQIAePLRIHGKLSKKEARKEAVLLLLVGVGLPEeVLNRYPHELSGGQRQRVAIARAL 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446554041 152 CMDPIAMLFDEPTSALDPEMINEVLDVMVELANE-GMTMMVVTHEMGFARKVANRVIFMDEGKIIED 217
Cdd:cd03257 161 ALNPKLLIADEPTSALDVSVQAQILDLLKKLQEElGLTLLFITHDLGVVAKIADRVAVMYAGKIVEE 227
|
|
| PstB |
COG1117 |
ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism]; ... |
2-236 |
3.25e-60 |
|
ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440734 [Multi-domain] Cd Length: 258 Bit Score: 190.25 E-value: 3.25e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 2 ITLKNVSKWYGHFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNG---LEPVQ--QGEITVDGIVVNDKKTDLAKLR 76
Cdd:COG1117 12 IEVRNLNVYYGDKQALKDINLDIPENKVTALIGPSGCGKSTLLRCLNRmndLIPGArvEGEILLDGEDIYDPDVDVVELR 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 77 SRVGMVFQHFELFPHlSIIENLTLAqVKVL-KRNKAPAREKALKLLERVGL----------SAHAnkfpaqLSGGQQQRV 145
Cdd:COG1117 92 RRVGMVFQKPNPFPK-SIYDNVAYG-LRLHgIKSKSELDEIVEESLRKAALwdevkdrlkkSALG------LSGGQQQRL 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 146 AIARALCMDPIAMLFDEPTSALDPemIN----EvlDVMVELANEgMTMMVVTHEMGFARKVANRVIFMDEGKIIEDSPKD 221
Cdd:COG1117 164 CIARALAVEPEVLLMDEPTSALDP--IStakiE--ELILELKKD-YTIVIVTHNMQQAARVSDYTAFFYLGELVEFGPTE 238
|
250
....*....|....*
gi 446554041 222 AFFDNPKSDRAKDFL 236
Cdd:COG1117 239 QIFTNPKDKRTEDYI 253
|
|
| ABC_phnC |
TIGR02315 |
phosphonate ABC transporter, ATP-binding protein; Phosphonates are a class of ... |
1-225 |
1.76e-59 |
|
phosphonate ABC transporter, ATP-binding protein; Phosphonates are a class of phosphorus-containing organic compound with a stable direct C-P bond rather than a C-O-P linkage. A number of bacterial species have operons, typically about 14 genes in size, with genes for ATP-dependent transport of phosphonates, degradation, and regulation of the expression of the system. Members of this protein family are the ATP-binding cassette component of tripartite ABC transporters of phosphonates. [Transport and binding proteins, Anions]
Pssm-ID: 131368 [Multi-domain] Cd Length: 243 Bit Score: 187.89 E-value: 1.76e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 1 MITLKNVSKWYGH-FQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQQGEITVDGI-VVNDKKTDLAKLRSR 78
Cdd:TIGR02315 1 MLEVENLSKVYPNgKQALKNINLNINPGEFVAIIGPSGAGKSTLLRCINRLVEPSSGSILLEGTdITKLRGKKLRKLRRR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 79 VGMVFQHFELFPHLSIIENLTLAQV-------KVLKRNKAPAREKALKLLERVGLSAHANKFPAQLSGGQQQRVAIARAL 151
Cdd:TIGR02315 81 IGMIFQHYNLIERLTVLENVLHGRLgykptwrSLLGRFSEEDKERALSALERVGLADKAYQRADQLSGGQQQRVAIARAL 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446554041 152 CMDPIAMLFDEPTSALDPEMINEVLDVMVELANE-GMTMMVVTHEMGFARKVANRVIFMDEGKIIEDSPKDAFFD 225
Cdd:TIGR02315 161 AQQPDLILADEPIASLDPKTSKQVMDYLKRINKEdGITVIINLHQVDLAKKYADRIVGLKAGEIVFDGAPSELDD 235
|
|
| ABC_cobalt_CbiO_domain1 |
cd03225 |
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ... |
4-213 |
2.59e-59 |
|
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.
Pssm-ID: 213192 [Multi-domain] Cd Length: 211 Bit Score: 186.13 E-value: 2.59e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 4 LKNVSKWYGHF--QVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVndKKTDLAKLRSRVGM 81
Cdd:cd03225 2 LKNLSFSYPDGarPALDDISLTIKKGEFVLIVGPNGSGKSTLLRLLNGLLGPTSGEVLVDGKDL--TKLSLKELRRKVGL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 82 VFQHFEL-FPHLSIIENLTLAqVKVLKRNKAPAREKALKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMDPIAMLF 160
Cdd:cd03225 80 VFQNPDDqFFGPTVEEEVAFG-LENLGLPEEEIEERVEEALELVGLEGLRDRSPFTLSGGQKQRVAIAGVLAMDPDILLL 158
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 446554041 161 DEPTSALDPEMINEVLDVMVELANEGMTMMVVTHEMGFARKVANRVIFMDEGK 213
Cdd:cd03225 159 DEPTAGLDPAGRRELLELLKKLKAEGKTIIIVTHDLDLLLELADRVIVLEDGK 211
|
|
| ABC_PotA_N |
cd03300 |
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and ... |
2-236 |
1.01e-58 |
|
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and the ATPase component of the spermidine/putrescine-preferential uptake system consisting of PotA, -B, -C, and -D. PotA has two domains with the N-terminal domain containing the ATPase activity and the residues required for homodimerization with PotA and heterdimerization with PotB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213267 [Multi-domain] Cd Length: 232 Bit Score: 185.52 E-value: 1.01e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 2 ITLKNVSKWYGHFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVndkkTDLAKLRSRVGM 81
Cdd:cd03300 1 IELENVSKFYGGFVALDGVSLDIKEGEFFTLLGPSGCGKTTLLRLIAGFETPTSGEILLDGKDI----TNLPPHKRPVNT 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 82 VFQHFELFPHLSIIENLTLAqVKVLKRNKAPAREKALKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMDPIAMLFD 161
Cdd:cd03300 77 VFQNYALFPHLTVFENIAFG-LRLKKLPKAEIKERVAEALDLVQLEGYANRKPSQLSGGQQQRVAIARALVNEPKVLLLD 155
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446554041 162 EPTSALDPEMINEVLDVMVELANE-GMTMMVVTHEMGFARKVANRVIFMDEGKIIE-DSPKDaFFDNPKSDRAKDFL 236
Cdd:cd03300 156 EPLGALDLKLRKDMQLELKRLQKElGITFVFVTHDQEEALTMSDRIAVMNKGKIQQiGTPEE-IYEEPANRFVADFI 231
|
|
| ABC_NrtD_SsuB_transporters |
cd03293 |
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ... |
2-217 |
3.49e-58 |
|
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ATP-binding subunits of the bacterial ABC-type nitrate and sulfonate transport systems, respectively. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213260 [Multi-domain] Cd Length: 220 Bit Score: 183.83 E-value: 3.49e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 2 ITLKNVSKWYGH----FQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVNDkktdlakLRS 77
Cdd:cd03293 1 LEVRNVSKTYGGgggaVTALEDISLSVEEGEFVALVGPSGCGKSTLLRIIAGLERPTSGEVLVDGEPVTG-------PGP 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 78 RVGMVFQHFELFPHLSIIENLTLAqVKVLKRNKAPAREKALKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMDPIA 157
Cdd:cd03293 74 DRGYVFQQDALLPWLTVLDNVALG-LELQGVPKAEARERAEELLELVGLSGFENAYPHQLSGGMRQRVALARALAVDPDV 152
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446554041 158 MLFDEPTSALDP----EMINEVLDVmveLANEGMTMMVVTHEMGFARKVANRVIFMDE--GKIIED 217
Cdd:cd03293 153 LLLDEPFSALDAltreQLQEELLDI---WRETGKTVLLVTHDIDEAVFLADRVVVLSArpGRIVAE 215
|
|
| ABC_OpuCA_Osmoprotection |
cd03295 |
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding ... |
2-238 |
4.88e-58 |
|
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing in a hyperosmolar environment. ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition, to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213262 [Multi-domain] Cd Length: 242 Bit Score: 184.04 E-value: 4.88e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 2 ITLKNVSKWYGH-FQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGL-EPvQQGEITVDGIVVNDkkTDLAKLRSRV 79
Cdd:cd03295 1 IEFENVTKRYGGgKKAVNNLNLEIAKGEFLVLIGPSGSGKTTTMKMINRLiEP-TSGEIFIDGEDIRE--QDPVELRRKI 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 80 GMVFQHFELFPHLSIIENLTLAQvKVLKRNKAPAREKALKLLERVGL--SAHANKFPAQLSGGQQQRVAIARALCMDPIA 157
Cdd:cd03295 78 GYVIQQIGLFPHMTVEENIALVP-KLLKWPKEKIRERADELLALVGLdpAEFADRYPHELSGGQQQRVGVARALAADPPL 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 158 MLFDEPTSALDPEMINEVLDVMVELANE-GMTMMVVTHEMGFARKVANRVIFMDEGKIIEDSPKDAFFDNPKSDRAKDFL 236
Cdd:cd03295 157 LLMDEPFGALDPITRDQLQEEFKRLQQElGKTIVFVTHDIDEAFRLADRIAIMKNGEIVQVGTPDEILRSPANDFVAEFV 236
|
..
gi 446554041 237 AK 238
Cdd:cd03295 237 GA 238
|
|
| ProV |
COG4175 |
ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and ... |
34-239 |
2.06e-57 |
|
ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443334 [Multi-domain] Cd Length: 389 Bit Score: 186.85 E-value: 2.06e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEPVQQGEITVDGI-VVNDKKTDLAKLR-SRVGMVFQHFELFPHLSIIEN----LTLAQVkvlk 107
Cdd:COG4175 60 GLSGSGKSTLVRCLNRLIEPTAGEVLIDGEdITKLSKKELRELRrKKMSMVFQHFALLPHRTVLENvafgLEIQGV---- 135
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 108 rNKAPAREKALKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDP----EMINEVLDVMVELa 183
Cdd:COG4175 136 -PKAERRERAREALELVGLAGWEDSYPDELSGGMQQRVGLARALATDPDILLMDEAFSALDPlirrEMQDELLELQAKL- 213
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 446554041 184 neGMTMMVVTHEMGFARKVANRVIFMDEGKII-EDSPKDaFFDNPKSDRAKDFLAKI 239
Cdd:COG4175 214 --KKTIVFITHDLDEALRLGDRIAIMKDGRIVqIGTPEE-ILTNPANDYVADFVEDV 267
|
|
| OpuBA |
COG1125 |
ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and ... |
1-236 |
3.86e-57 |
|
ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 440742 [Multi-domain] Cd Length: 306 Bit Score: 183.75 E-value: 3.86e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 1 MITLKNVSKWYGHFQV-LTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQQGEITVDGivVNDKKTDLAKLRSRV 79
Cdd:COG1125 1 MIEFENVTKRYPDGTVaVDDLSLTIPAGEFTVLVGPSGCGKTTTLRMINRLIEPTSGRILIDG--EDIRDLDPVELRRRI 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 80 GMVFQHFELFPHLSIIENLtlAQV-KVLKRNKAPAREKALKLLERVGL--SAHANKFPAQLSGGQQQRVAIARALCMDPI 156
Cdd:COG1125 79 GYVIQQIGLFPHMTVAENI--ATVpRLLGWDKERIRARVDELLELVGLdpEEYRDRYPHELSGGQQQRVGVARALAADPP 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 157 AMLFDEPTSALDP----EMINEVLDVMVELaneGMTMMVVTHEMGFARKVANRVIFMDEGKIIE-DSPkDAFFDNPKSDR 231
Cdd:COG1125 157 ILLMDEPFGALDPitreQLQDELLRLQREL---GKTIVFVTHDIDEALKLGDRIAVMREGRIVQyDTP-EEILANPANDF 232
|
....*
gi 446554041 232 AKDFL 236
Cdd:COG1125 233 VADFV 237
|
|
| MalK |
COG3839 |
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism]; ... |
1-229 |
8.49e-56 |
|
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism];
Pssm-ID: 443050 [Multi-domain] Cd Length: 352 Bit Score: 181.81 E-value: 8.49e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 1 MITLKNVSKWYGHFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVNDKKtdlAKLRsRVG 80
Cdd:COG3839 3 SLELENVSKSYGGVEALKDIDLDIEDGEFLVLLGPSGCGKSTLLRMIAGLEDPTSGEILIGGRDVTDLP---PKDR-NIA 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 81 MVFQHFELFPHLSIIENLTLAqVKVLKRNKAPAREKALKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMDPIAMLF 160
Cdd:COG3839 79 MVFQSYALYPHMTVYENIAFP-LKLRKVPKAEIDRRVREAAELLGLEDLLDRKPKQLSGGQRQRVALGRALVREPKVFLL 157
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446554041 161 DEPTSALDP----EMINEVLDVMVELaneGMTMMVVTHE----MGFarkvANRVIFMDEGKIIE-DSPKDaFFDNPKS 229
Cdd:COG3839 158 DEPLSNLDAklrvEMRAEIKRLHRRL---GTTTIYVTHDqveaMTL----ADRIAVMNDGRIQQvGTPEE-LYDRPAN 227
|
|
| ABC_CysA_sulfate_importer |
cd03296 |
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex ... |
2-236 |
1.53e-55 |
|
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex cysAWTP involved in sulfate import. Responsible for energy coupling to the transport system. The complex is composed of two ATP-binding proteins (cysA), two transmembrane proteins (cysT and cysW), and a solute-binding protein (cysP). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213263 [Multi-domain] Cd Length: 239 Bit Score: 177.53 E-value: 1.53e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 2 ITLKNVSKWYGHFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVNDKKtdlakLRSR-VG 80
Cdd:cd03296 3 IEVRNVSKRFGDFVALDDVSLDIPSGELVALLGPSGSGKTTLLRLIAGLERPDSGTILFGGEDATDVP-----VQERnVG 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 81 MVFQHFELFPHLSIIENLTLAqVKVLKR----NKAPAREKALKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMDPI 156
Cdd:cd03296 78 FVFQHYALFRHMTVFDNVAFG-LRVKPRserpPEAEIRAKVHELLKLVQLDWLADRYPAQLSGGQRQRVALARALAVEPK 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 157 AMLFDEPTSALDPEMINEVLDVMVELANE-GMTMMVVTHEMGFARKVANRVIFMDEGKIIEDSPKDAFFDNPKSDRAKDF 235
Cdd:cd03296 157 VLLLDEPFGALDAKVRKELRRWLRRLHDElHVTTVFVTHDQEEALEVADRVVVMNKGRIEQVGTPDEVYDHPASPFVYSF 236
|
.
gi 446554041 236 L 236
Cdd:cd03296 237 L 237
|
|
| ABC_Pro_Gly_Betaine |
cd03294 |
ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This ... |
34-235 |
1.97e-55 |
|
ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This family comprises the glycine betaine/L-proline ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporters is the obligatory coupling of ATP hydrolysis to substrate translocation. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213261 [Multi-domain] Cd Length: 269 Bit Score: 178.22 E-value: 1.97e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEPVQQGEITVDG---IVVNDKktDLAKLRS-RVGMVFQHFELFPHLSIIENLTLAqVKVLKRN 109
Cdd:cd03294 57 GLSGSGKSTLLRCINRLIEPTSGKVLIDGqdiAAMSRK--ELRELRRkKISMVFQSFALLPHRTVLENVAFG-LEVQGVP 133
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 110 KAPAREKALKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDP----EMINEVLDVMvelANE 185
Cdd:cd03294 134 RAEREERAAEALELVGLEGWEHKYPDELSGGMQQRVGLARALAVDPDILLMDEAFSALDPlirrEMQDELLRLQ---AEL 210
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 446554041 186 GMTMMVVTHEMGFARKVANRVIFMDEGKIIEDSPKDAFFDNPKSDRAKDF 235
Cdd:cd03294 211 QKTIVFITHDLDEALRLGDRIAIMKDGRLVQVGTPEEILTNPANDYVREF 260
|
|
| GsiA |
COG1123 |
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ... |
1-232 |
9.67e-55 |
|
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440740 [Multi-domain] Cd Length: 514 Bit Score: 183.18 E-value: 9.67e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 1 MITLKNVSKWY--GHFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEP---VQQGEITVDGivVNDKKTDLAKL 75
Cdd:COG1123 4 LLEVRDLSVRYpgGDVPAVDGVSLTIAPGETVALVGESGSGKSTLALALMGLLPhggRISGEVLLDG--RDLLELSEALR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 76 RSRVGMVFQHFE--LFPhLSIIENLTLAqVKVLKRNKAPAREKALKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCM 153
Cdd:COG1123 82 GRRIGMVFQDPMtqLNP-VTVGDQIAEA-LENLGLSRAEARARVLELLEAVGLERRLDRYPHQLSGGQRQRVAIAMALAL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 154 DPIAMLFDEPTSALDPEMINEVLDVMVELANE-GMTMMVVTHEMGFARKVANRVIFMDEGKIIEDSPKDAFFDNPKSDRA 232
Cdd:COG1123 160 DPDLLIADEPTTALDVTTQAEILDLLRELQRErGTTVLLITHDLGVVAEIADRVVVMDDGRIVEDGPPEEILAAPQALAA 239
|
|
| ZnuC |
COG1121 |
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism]; ... |
1-223 |
1.14e-54 |
|
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440738 [Multi-domain] Cd Length: 245 Bit Score: 175.66 E-value: 1.14e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 1 MITLKNVSKWYGHFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQQGEITVDGivvndkkTDLAKLRSRVG 80
Cdd:COG1121 6 AIELENLTVSYGGRPVLEDVSLTIPPGEFVAIVGPNGAGKSTLLKAILGLLPPTSGTVRLFG-------KPPRRARRRIG 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 81 MVFQHFEL---FPhLSIIENLTL---AQVKVLKRNKAPAREKALKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMD 154
Cdd:COG1121 79 YVPQRAEVdwdFP-ITVRDVVLMgryGRRGLFRRPSRADREAVDEALERVGLEDLADRPIGELSGGQQQRVLLARALAQD 157
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446554041 155 PIAMLFDEPTSALDPEMINEVLDVMVELANEGMTMMVVTHEMGFARKVANRVIFMDEGKIIEDSPKDAF 223
Cdd:COG1121 158 PDLLLLDEPFAGVDAATEEALYELLRELRREGKTILVVTHDLGAVREYFDRVLLLNRGLVAHGPPEEVL 226
|
|
| FtsE |
TIGR02673 |
cell division ATP-binding protein FtsE; This model describes FtsE, a member of the ABC ... |
1-213 |
3.07e-54 |
|
cell division ATP-binding protein FtsE; This model describes FtsE, a member of the ABC transporter ATP-binding protein family. This protein, and its permease partner FtsX, localize to the division site. In a number of species, the ftsEX gene pair is located next to FtsY, the signal recognition particle-docking protein. [Cellular processes, Cell division]
Pssm-ID: 131721 [Multi-domain] Cd Length: 214 Bit Score: 173.59 E-value: 3.07e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 1 MITLKNVSKWY-GHFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVND-KKTDLAKLRSR 78
Cdd:TIGR02673 1 MIEFHNVSKAYpGGVAALHDVSLHIRKGEFLFLTGPSGAGKTTLLKLLYGALTPSRGQVRIAGEDVNRlRGRQLPLLRRR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 79 VGMVFQHFELFPHLSIIENLTLA-QVKVLKRNKAPAREKALklLERVGLSAHANKFPAQLSGGQQQRVAIARALCMDPIA 157
Cdd:TIGR02673 81 IGVVFQDFRLLPDRTVYENVALPlEVRGKKEREIQRRVGAA--LRQVGLEHKADAFPEQLSGGEQQRVAIARAIVNSPPL 158
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 446554041 158 MLFDEPTSALDPEMINEVLDVMVELANEGMTMMVVTHEMGFARKVANRVIFMDEGK 213
Cdd:TIGR02673 159 LLADEPTGNLDPDLSERILDLLKRLNKRGTTVIVATHDLSLVDRVAHRVIILDDGR 214
|
|
| FetA |
COG4619 |
ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism]; |
33-214 |
4.54e-54 |
|
ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443661 [Multi-domain] Cd Length: 209 Bit Score: 172.69 E-value: 4.54e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 33 CGPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVNDkkTDLAKLRSRVGMVFQHFELFPHlSIIENLTLAqvkVLKRNKAP 112
Cdd:COG4619 32 TGPSGSGKSTLLRALADLDPPTSGEIYLDGKPLSA--MPPPEWRRQVAYVPQEPALWGG-TVRDNLPFP---FQLRERKF 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 113 AREKALKLLERVGLSAHANKFPA-QLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLDVMVEL-ANEGMTMM 190
Cdd:COG4619 106 DRERALELLERLGLPPDILDKPVeRLSGGERQRLALIRALLLQPDVLLLDEPTSALDPENTRRVEELLREYlAEEGRAVL 185
|
170 180
....*....|....*....|....
gi 446554041 191 VVTHEMGFARKVANRVIFMDEGKI 214
Cdd:COG4619 186 WVSHDPEQIERVADRVLTLEAGRL 209
|
|
| PRK10851 |
PRK10851 |
sulfate/thiosulfate ABC transporter ATP-binding protein CysA; |
2-241 |
2.94e-53 |
|
sulfate/thiosulfate ABC transporter ATP-binding protein CysA;
Pssm-ID: 182778 [Multi-domain] Cd Length: 353 Bit Score: 175.27 E-value: 2.94e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 2 ITLKNVSKWYGHFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQQGEITVDGivvndkkTDLAKLRSR--- 78
Cdd:PRK10851 3 IEIANIKKSFGRTQVLNDISLDIPSGQMVALLGPSGSGKTTLLRIIAGLEHQTSGHIRFHG-------TDVSRLHARdrk 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 79 VGMVFQHFELFPHLSIIENLTLAqVKVLKRNKAPA----REKALKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMD 154
Cdd:PRK10851 76 VGFVFQHYALFRHMTVFDNIAFG-LTVLPRRERPNaaaiKAKVTQLLEMVQLAHLADRYPAQLSGGQKQRVALARALAVE 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 155 PIAMLFDEPTSALDPEMINEVLDVMVELANE-GMTMMVVTHEMGFARKVANRVIFMDEGKIIE-DSPKDAFFDnPKSDRA 232
Cdd:PRK10851 155 PQILLLDEPFGALDAQVRKELRRWLRQLHEElKFTSVFVTHDQEEAMEVADRVVVMSQGNIEQaGTPDQVWRE-PATRFV 233
|
....*....
gi 446554041 233 KDFLAKILH 241
Cdd:PRK10851 234 LEFMGEVNR 242
|
|
| DppD |
COG0444 |
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ... |
34-228 |
3.28e-52 |
|
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];
Pssm-ID: 440213 [Multi-domain] Cd Length: 320 Bit Score: 171.39 E-value: 3.28e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEP---VQQGEITVDGI-VVNDKKTDLAKLR-SRVGMVFQhfE----LFPHLSIIENLTLAQVK 104
Cdd:COG0444 38 GESGSGKSTLARAILGLLPppgITSGEILFDGEdLLKLSEKELRKIRgREIQMIFQ--DpmtsLNPVMTVGDQIAEPLRI 115
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 105 VLKRNKAPAREKALKLLERVGLS---AHANKFPAQLSGGQQQRVAIARALCMDP---IAmlfDEPTSALDPEMINEVLDV 178
Cdd:COG0444 116 HGGLSKAEARERAIELLERVGLPdpeRRLDRYPHELSGGMRQRVMIARALALEPkllIA---DEPTTALDVTIQAQILNL 192
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 446554041 179 MVELANE-GMTMMVVTHEMGFARKVANRVIFMDEGKIIEDSPKDAFFDNPK 228
Cdd:COG0444 193 LKDLQRElGLAILFITHDLGVVAEIADRVAVMYAGRIVEEGPVEELFENPR 243
|
|
| YbbA |
COG4181 |
Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase ... |
1-222 |
7.99e-52 |
|
Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 443338 [Multi-domain] Cd Length: 233 Bit Score: 168.00 E-value: 7.99e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 1 MITLKNVSKWY----GHFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQQGEITVDGivvndkkTDL---- 72
Cdd:COG4181 8 IIELRGLTKTVgtgaGELTILKGISLEVEAGESVAIVGASGSGKSTLLGLLAGLDRPTSGTVRLAG-------QDLfald 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 73 ----AKLRSR-VGMVFQHFELFPHLSIIEN----LTLAQVKvlkrnkaPAREKALKLLERVGLSAHANKFPAQLSGGQQQ 143
Cdd:COG4181 81 edarARLRARhVGFVFQSFQLLPTLTALENvmlpLELAGRR-------DARARARALLERVGLGHRLDHYPAQLSGGEQQ 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 144 RVAIARALCMDPiAMLF-DEPTSALDPEMINEVLDVMVELANE-GMTMMVVTHEMGFARKvANRVIFMDEGKIIEDSPKD 221
Cdd:COG4181 154 RVALARAFATEP-AILFaDEPTGNLDAATGEQIIDLLFELNRErGTTLVLVTHDPALAAR-CDRVLRLRAGRLVEDTAAT 231
|
.
gi 446554041 222 A 222
Cdd:COG4181 232 A 232
|
|
| L_ocin_972_ABC |
TIGR03608 |
putative bacteriocin export ABC transporter, lactococcin 972 group; A gene pair with a fairly ... |
4-209 |
1.35e-50 |
|
putative bacteriocin export ABC transporter, lactococcin 972 group; A gene pair with a fairly wide distribution consists of a polypeptide related to the lactococcin 972 (see TIGR01653) and multiple-membrane-spanning putative immunity protein (see TIGR01654). This model represents a small clade within the ABC transporters that regularly are found adjacent to these bacteriocin system gene pairs and are likely serve as export proteins. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Unknown substrate]
Pssm-ID: 188353 [Multi-domain] Cd Length: 206 Bit Score: 163.94 E-value: 1.35e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 4 LKNVSKWYGHFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQQGEITVDG---IVVNDKKTDLAKlRSRVG 80
Cdd:TIGR03608 1 LKNISKKFGDKVILDDLNLTIEKGKMYAIIGESGSGKSTLLNIIGLLEKFDSGQVYLNGqetPPLNSKKASKFR-REKLG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 81 MVFQHFELFPHLSIIENLTLAqVKVLKRNKAPAREKALKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMDPIAMLF 160
Cdd:TIGR03608 80 YLFQNFALIENETVEENLDLG-LKYKKLSKKEKREKKKEALEKVGLNLKLKQKIYELSGGEQQRVALARAILKPPPLILA 158
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 446554041 161 DEPTSALDPEMINEVLDVMVELANEGMTMMVVTHEMGFArKVANRVIFM 209
Cdd:TIGR03608 159 DEPTGSLDPKNRDEVLDLLLELNDEGKTIIIVTHDPEVA-KQADRVIEL 206
|
|
| ModC |
COG4148 |
ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and ... |
34-215 |
1.98e-50 |
|
ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and metabolism]; ABC-type molybdate transport system, ATPase component ModC is part of the Pathway/BioSystem: Molybdopterin biosynthesis
Pssm-ID: 443319 [Multi-domain] Cd Length: 358 Bit Score: 167.97 E-value: 1.98e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVND--KKTDLAKLRSRVGMVFQHFELFPHLSIIENLTLAQvkvlKRNKA 111
Cdd:COG4148 32 GPSGSGKTTLLRAIAGLERPDSGRIRLGGEVLQDsaRGIFLPPHRRRIGYVFQEARLFPHLSVRGNLLYGR----KRAPR 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 112 PAREKAL-KLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLDVMVELANE-GMTM 189
Cdd:COG4148 108 AERRISFdEVVELLGIGHLLDRRPATLSGGERQRVAIGRALLSSPRLLLMDEPLAALDLARKAEILPYLERLRDElDIPI 187
|
170 180
....*....|....*....|....*.
gi 446554041 190 MVVTHEMGFARKVANRVIFMDEGKII 215
Cdd:COG4148 188 LYVSHSLDEVARLADHVVLLEQGRVV 213
|
|
| ABC_Mj1267_LivG_branched |
cd03219 |
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ... |
34-228 |
6.88e-50 |
|
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ABC transporter subfamily is involved in the transport of the hydrophobic amino acids leucine, isoleucine and valine. MJ1267 is a branched-chain amino acid transporter with 29% similarity to both the LivF and LivG components of the E. coli branched-chain amino acid transporter. MJ1267 contains an insertion from residues 114 to 123 characteristic of LivG (Leucine-Isoleucine-Valine) homologs. The branched-chain amino acid transporter from E. coli comprises a heterodimer of ABCs (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ).
Pssm-ID: 213186 [Multi-domain] Cd Length: 236 Bit Score: 162.99 E-value: 6.88e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVNDKKTDLaklRSRVGMV--FQHFELFPHLSIIENLTLAQVKVLK---- 107
Cdd:cd03219 33 GPNGAGKTTLFNLISGFLRPTSGSVLFDGEDITGLPPHE---IARLGIGrtFQIPRLFPELTVLENVMVAAQARTGsgll 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 108 -----RNKAPAREKALKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLDVMVEL 182
Cdd:cd03219 110 lararREEREARERAEELLERVGLADLADRPAGELSYGQQRRLEIARALATDPKLLLLDEPAAGLNPEETEELAELIREL 189
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 446554041 183 ANEGMTMMVVTHEMGFARKVANRVIFMDEGKIIEDSPKDAFFDNPK 228
Cdd:cd03219 190 RERGITVLLVEHDMDVVMSLADRVTVLDQGRVIAEGTPDEVRNNPR 235
|
|
| ECF_ATPase_1 |
TIGR04520 |
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette ... |
34-223 |
1.56e-49 |
|
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the upstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 275313 [Multi-domain] Cd Length: 268 Bit Score: 162.98 E-value: 1.56e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVNDKKTdLAKLRSRVGMVFQH---------------FELfphlsiiENL 98
Cdd:TIGR04520 35 GHNGSGKSTLAKLLNGLLLPTSGKVTVDGLDTLDEEN-LWEIRKKVGMVFQNpdnqfvgatveddvaFGL-------ENL 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 99 TLAQVKVLKR-NKAparekalklLERVGLSAHANKFPAQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLD 177
Cdd:TIGR04520 107 GVPREEMRKRvDEA---------LKLVGMEDFRDREPHLLSGGQKQRVAIAGVLAMRPDIIILDEATSMLDPKGRKEVLE 177
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 446554041 178 VMVELANE-GMTMMVVTHEMGFARKvANRVIFMDEGKII-EDSPKDAF 223
Cdd:TIGR04520 178 TIRKLNKEeGITVISITHDMEEAVL-ADRVIVMNKGKIVaEGTPREIF 224
|
|
| LivG |
COG0411 |
ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid ... |
1-228 |
2.69e-49 |
|
ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid transport and metabolism];
Pssm-ID: 440180 [Multi-domain] Cd Length: 257 Bit Score: 162.13 E-value: 2.69e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 1 MITLKNVSKWYGHFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVNDKKTDLaklRSRVG 80
Cdd:COG0411 4 LLEVRGLTKRFGGLVAVDDVSLEVERGEIVGLIGPNGAGKTTLFNLITGFYRPTSGRILFDGRDITGLPPHR---IARLG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 81 MV--FQHFELFPHLSIIENLTLAQ--------------VKVLKRNKAPAREKALKLLERVGLSAHANKFPAQLSGGQQQR 144
Cdd:COG0411 81 IArtFQNPRLFPELTVLENVLVAAharlgrgllaallrLPRARREEREARERAEELLERVGLADRADEPAGNLSYGQQRR 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 145 VAIARALCMDPIAMLFDEPTSALDPEMINEVLDVMVELANE-GMTMMVVTHEMGFARKVANRVIFMDEGKII-EDSPkDA 222
Cdd:COG0411 161 LEIARALATEPKLLLLDEPAAGLNPEETEELAELIRRLRDErGITILLIEHDMDLVMGLADRIVVLDFGRVIaEGTP-AE 239
|
....*.
gi 446554041 223 FFDNPK 228
Cdd:COG0411 240 VRADPR 245
|
|
| PhnT2 |
TIGR03265 |
putative 2-aminoethylphosphonate ABC transporter, ATP-binding protein; This ABC transporter ... |
2-239 |
3.60e-49 |
|
putative 2-aminoethylphosphonate ABC transporter, ATP-binding protein; This ABC transporter ATP-binding protein is found in a number of genomes in operon-like contexts strongly suggesting a substrate specificity for 2-aminoethylphosphonate (2-AEP). The characterized PhnSTUV system is absent in the genomes in which this system is found. These genomes encode systems for the catabolism of 2-AEP, making the need for a 2-AEP-specific transporter likely. [Transport and binding proteins, Amino acids, peptides and amines]
Pssm-ID: 274496 [Multi-domain] Cd Length: 353 Bit Score: 164.82 E-value: 3.60e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 2 ITLKNVSKWYGHFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQQGEITVDGivvNDKkTDLAKLRSRVGM 81
Cdd:TIGR03265 5 LSIDNIRKRFGAFTALKDISLSVKKGEFVCLLGPSGCGKTTLLRIIAGLERQTAGTIYQGG---RDI-TRLPPQKRDYGI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 82 VFQHFELFPHLSIIENLTLAqVKVLKRNKAPAREKALKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMDPIAMLFD 161
Cdd:TIGR03265 81 VFQSYALFPNLTVADNIAYG-LKNRGMGRAEVAERVAELLDLVGLPGSERKYPGQLSGGQQQRVALARALATSPGLLLLD 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 162 EPTSALDPEminevldVMVELANE--------GMTMMVVTHEMGFARKVANRVIFMDEGKIIEDSPKDAFFDNPKSDRAK 233
Cdd:TIGR03265 160 EPLSALDAR-------VREHLRTEirqlqrrlGVTTIMVTHDQEEALSMADRIVVMNHGVIEQVGTPQEIYRHPATPFVA 232
|
....*.
gi 446554041 234 DFLAKI 239
Cdd:TIGR03265 233 DFVGEV 238
|
|
| NatA |
COG4555 |
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, ... |
1-240 |
7.51e-49 |
|
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, Inorganic ion transport and metabolism];
Pssm-ID: 443618 [Multi-domain] Cd Length: 243 Bit Score: 160.79 E-value: 7.51e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 1 MITLKNVSKWYGHFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQQGEITVDGIvvnDKKTDLAKLRSRVG 80
Cdd:COG4555 1 MIEVENLSKKYGKVPALKDVSFTAKDGEITGLLGPNGAGKTTLLRMLAGLLKPDSGSILIDGE---DVRKEPREARRQIG 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 81 MVFQHFELFPHLSIIENLTLAqVKVLKRNKAPAREKALKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMDPIAMLF 160
Cdd:COG4555 78 VLPDERGLYDRLTVRENIRYF-AELYGLFDEELKKRIEELIELLGLEEFLDRRVGELSTGMKKKVALARALVHDPKVLLL 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 161 DEPTSALDPEMINEVLDVMVELANEGMTMMVVTHEMGFARKVANRVIFMDEGKIIEDSPKDAFFDNPKSDRAKDFLAKIL 240
Cdd:COG4555 157 DEPTNGLDVMARRLLREILRALKKEGKTVLFSSHIMQEVEALCDRVVILHKGKVVAQGSLDELREEIGEENLEDAFVALI 236
|
|
| ECF_ATPase_2 |
TIGR04521 |
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette ... |
2-239 |
9.40e-49 |
|
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the downstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 275314 [Multi-domain] Cd Length: 277 Bit Score: 161.47 E-value: 9.40e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 2 ITLKNVSKWYG-----HFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVN-DKKTDLAKL 75
Cdd:TIGR04521 1 IKLKNVSYIYQpgtpfEKKALDDVSLTIEDGEFVAIIGHTGSGKSTLIQHLNGLLKPTSGTVTIDGRDITaKKKKKLKDL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 76 RSRVGMVFQhfelFPHLSIIENLTLAQV----KVLKRNKAPAREKALKLLERVGLSAH-ANKFPAQLSGGQQQRVAIARA 150
Cdd:TIGR04521 81 RKKVGLVFQ----FPEHQLFEETVYKDIafgpKNLGLSEEEAEERVKEALELVGLDEEyLERSPFELSGGQMRRVAIAGV 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 151 LCMDPIAMLFDEPTSALDPEMINEVLDVMVELANE-GMTMMVVTHEMGFARKVANRVIFMDEGKIIED-SPKDAFFDnpk 228
Cdd:TIGR04521 157 LAMEPEVLILDEPTAGLDPKGRKEILDLFKRLHKEkGLTVILVTHSMEDVAEYADRVIVMHKGKIVLDgTPREVFSD--- 233
|
250
....*....|.
gi 446554041 229 sdraKDFLAKI 239
Cdd:TIGR04521 234 ----VDELEKI 240
|
|
| ABC_DR_subfamily_A |
cd03230 |
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily ... |
2-214 |
1.51e-48 |
|
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; This family of ATP-binding proteins belongs to a multi-subunit transporter involved in drug resistance (BcrA and DrrA), nodulation, lipid transport, and lantibiotic immunity. In bacteria and archaea, these transporters usually include an ATP-binding protein and one or two integral membrane proteins. Eukaryotic systems of the ABCA subfamily display ABC domains that are quite similar to this family. The ATP-binding domain shows the highest similarity between all members of the ABC transporter family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213197 [Multi-domain] Cd Length: 173 Bit Score: 157.56 E-value: 1.51e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 2 ITLKNVSKWYGHFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQQGEITVDGIvvnDKKTDLAKLRSRVGM 81
Cdd:cd03230 1 IEVRNLSKRYGKKTALDDISLTVEKGEIYGLLGPNGAGKTTLIKIILGLLKPDSGEIKVLGK---DIKKEPEEVKRRIGY 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 82 VFQHFELFPHLSIIENLtlaqvkvlkrnkaparekalkllervglsahankfpaQLSGGQQQRVAIARALCMDPIAMLFD 161
Cdd:cd03230 78 LPEEPSLYENLTVRENL-------------------------------------KLSGGMKQRLALAQALLHDPELLILD 120
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 446554041 162 EPTSALDPEMINEVLDVMVELANEGMTMMVVTHEMGFARKVANRVIFMDEGKI 214
Cdd:cd03230 121 EPTSGLDPESRREFWELLRELKKEGKTILLSSHILEEAERLCDRVAILNNGRI 173
|
|
| proV |
TIGR01186 |
glycine betaine/L-proline transport ATP binding subunit; This model describes the glycine ... |
34-239 |
3.35e-48 |
|
glycine betaine/L-proline transport ATP binding subunit; This model describes the glycine betaine/L-proline ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. Functionally, this transport system is involved in osmoregulation. Under conditions of stress, the organism recruits these transport system to accumulate glycine betaine and other solutes which offer osmo-protection. It has been demonstrated that glycine betaine uptake is accompanied by symport with sodium ions. The locus has been named variously as proU or opuA. A gene library from L.lactis functionally complements an E.coli proU mutant. The comlementing locus is similar to a opuA locus in B.sutlis. This clarifies the differences in nomenclature. [Transport and binding proteins, Amino acids, peptides and amines]
Pssm-ID: 130254 [Multi-domain] Cd Length: 363 Bit Score: 162.33 E-value: 3.35e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEPVQQGEITVDGI-VVNDKKTDLAKLRSR-VGMVFQHFELFPHLSIIENLTLAqVKVLKRNKA 111
Cdd:TIGR01186 26 GLSGSGKSTTVRMLNRLIEPTAGQIFIDGEnIMKQSPVELREVRRKkIGMVFQQFALFPHMTILQNTSLG-PELLGWPEQ 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 112 PAREKALKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLDVMVEL-ANEGMTMM 190
Cdd:TIGR01186 105 ERKEKALELLKLVGLEEYEHRYPDELSGGMQQRVGLARALAAEPDILLMDEAFSALDPLIRDSMQDELKKLqATLQKTIV 184
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 446554041 191 VVTHEMGFARKVANRVIFMDEGKIIEDSPKDAFFDNPKSDRAKDFLAKI 239
Cdd:TIGR01186 185 FITHDLDEAIRIGDRIVIMKAGEIVQVGTPDEILRNPANEYVEEFIGKV 233
|
|
| FepC |
COG1120 |
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion ... |
1-221 |
8.65e-48 |
|
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion transport and metabolism, Coenzyme transport and metabolism];
Pssm-ID: 440737 [Multi-domain] Cd Length: 254 Bit Score: 158.28 E-value: 8.65e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 1 MITLKNVSKWYGHFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQQGEITVDGivvndkkTDLAKLRSR-- 78
Cdd:COG1120 1 MLEAENLSVGYGGRPVLDDVSLSLPPGEVTALLGPNGSGKSTLLRALAGLLKPSSGEVLLDG-------RDLASLSRRel 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 79 ---VGMVFQHFELFPHLSIIENLTL---AQVKVLKRNKAPAREKALKLLERVGLSAHANKFPAQLSGGQQQRVAIARALC 152
Cdd:COG1120 74 arrIAYVPQEPPAPFGLTVRELVALgryPHLGLFGRPSAEDREAVEEALERTGLEHLADRPVDELSGGERQRVLIARALA 153
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446554041 153 MDPIAMLFDEPTSALDPEMINEVLDVMVELANE-GMTMMVVTHEMGFARKVANRVIFMDEGKII-EDSPKD 221
Cdd:COG1120 154 QEPPLLLLDEPTSHLDLAHQLEVLELLRRLARErGRTVVMVLHDLNLAARYADRLVLLKDGRIVaQGPPEE 224
|
|
| ABC_Metallic_Cations |
cd03235 |
ATP-binding cassette domain of the metal-type transporters; This family includes transporters ... |
4-214 |
2.26e-47 |
|
ATP-binding cassette domain of the metal-type transporters; This family includes transporters involved in the uptake of various metallic cations such as iron, manganese, and zinc. The ATPases of this group of transporters are very similar to members of iron-siderophore uptake family suggesting that they share a common ancestor. The best characterized metal-type ABC transporters are the YfeABCD system of Y. pestis, the SitABCD system of Salmonella enterica serovar Typhimurium, and the SitABCD transporter of Shigella flexneri. Moreover other uncharacterized homologs of these metal-type transporters are mainly found in pathogens like Haemophilus or enteroinvasive E. coli isolates.
Pssm-ID: 213202 [Multi-domain] Cd Length: 213 Bit Score: 155.77 E-value: 2.26e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 4 LKNVSKWYGHFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQQGEITVDGIvvndkktDLAKLRSRVGMVF 83
Cdd:cd03235 2 VEDLTVSYGGHPVLEDVSFEVKPGEFLAIVGPNGAGKSTLLKAILGLLKPTSGSIRVFGK-------PLEKERKRIGYVP 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 84 QHFEL---FPhLSIIENLTL---AQVKVLKRNKAPAREKALKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMDPIA 157
Cdd:cd03235 75 QRRSIdrdFP-ISVRDVVLMglyGHKGLFRRLSKADKAKVDEALERVGLSELADRQIGELSGGQQQRVLLARALVQDPDL 153
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 446554041 158 MLFDEPTSALDPEMINEVLDVMVELANEGMTMMVVTHEMGFARKVANRVIFMDEGKI 214
Cdd:cd03235 154 LLLDEPFAGVDPKTQEDIYELLRELRREGMTILVVTHDLGLVLEYFDRVLLLNRTVV 210
|
|
| ABC_FtsE |
cd03292 |
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where ... |
2-214 |
4.24e-47 |
|
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages
Pssm-ID: 213259 [Multi-domain] Cd Length: 214 Bit Score: 155.26 E-value: 4.24e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 2 ITLKNVSKWYGH-FQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVND-KKTDLAKLRSRV 79
Cdd:cd03292 1 IEFINVTKTYPNgTAALDGINISISAGEFVFLVGPSGAGKSTLLKLIYKEELPTSGTIRVNGQDVSDlRGRAIPYLRRKI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 80 GMVFQHFELFPHLSIIENLTLAQVKVLKRNKApAREKALKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMDPIAML 159
Cdd:cd03292 81 GVVFQDFRLLPDRNVYENVAFALEVTGVPPRE-IRKRVPAALELVGLSHKHRALPAELSGGEQQRVAIARAIVNSPTILI 159
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 446554041 160 FDEPTSALDPEMINEVLDVMVELANEGMTMMVVTHEMGFARKVANRVIFMDEGKI 214
Cdd:cd03292 160 ADEPTGNLDPDTTWEIMNLLKKINKAGTTVVVATHAKELVDTTRHRVIALERGKL 214
|
|
| ABC_TM1139_LivF_branched |
cd03224 |
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of ... |
2-226 |
6.09e-47 |
|
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of the LIV-I bacterial ABC-type two-component transport system that imports neutral, branched-chain amino acids. The E. coli branched-chain amino acid transporter comprises a heterodimer of ABC transporters (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules.
Pssm-ID: 213191 [Multi-domain] Cd Length: 222 Bit Score: 154.90 E-value: 6.09e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 2 ITLKNVSKWYGHFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQQGEITVDGivvndkkTDLAKLRSR--- 78
Cdd:cd03224 1 LEVENLNAGYGKSQILFGVSLTVPEGEIVALLGRNGAGKTTLLKTIMGLLPPRSGSIRFDG-------RDITGLPPHera 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 79 ---VGMVFQHFELFPHLSIIENLTLAQVKVLKRNKAPAREKAL----KLLERvgLSAHAnkfpAQLSGGQQQRVAIARAL 151
Cdd:cd03224 74 ragIGYVPEGRRIFPELTVEENLLLGAYARRRAKRKARLERVYelfpRLKER--RKQLA----GTLSGGEQQMLAIARAL 147
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446554041 152 CMDPIAMLFDEPTSALDPEMINEVLDVMVELANEGMTMMVVTHEMGFARKVANRVIFMDEGKIIEDSPKDAFFDN 226
Cdd:cd03224 148 MSRPKLLLLDEPSEGLAPKIVEEIFEAIRELRDEGVTILLVEQNARFALEIADRAYVLERGRVVLEGTAAELLAD 222
|
|
| SunT |
COG2274 |
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase ... |
34-222 |
8.46e-47 |
|
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms];
Pssm-ID: 441875 [Multi-domain] Cd Length: 711 Bit Score: 164.62 E-value: 8.46e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEPVQQGEITVDGIvvNDKKTDLAKLRSRVGMVFQHFELFpHLSIIENLTLAqvkvlkrNKAPA 113
Cdd:COG2274 508 GRSGSGKSTLLKLLLGLYEPTSGRILIDGI--DLRQIDPASLRRQIGVVLQDVFLF-SGTIRENITLG-------DPDAT 577
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 114 REKALKLLERVGLSAHANKFP-----------AQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLDVMVEL 182
Cdd:COG2274 578 DEEIIEAARLAGLHDFIEALPmgydtvvgeggSNLSGGQRQRLAIARALLRNPRILILDEATSALDAETEAIILENLRRL 657
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 446554041 183 ANeGMTMMVVTHEMGFARKvANRVIFMDEGKIIEDSPKDA 222
Cdd:COG2274 658 LK-GRTVIIIAHRLSTIRL-ADRIIVLDKGRIVEDGTHEE 695
|
|
| ABC_ThiQ_thiamine_transporter |
cd03298 |
ATP-binding cassette domain of the thiamine transport system; Part of the ... |
2-217 |
1.30e-46 |
|
ATP-binding cassette domain of the thiamine transport system; Part of the binding-protein-dependent transport system tbpA-thiPQ for thiamine and TPP. Probably responsible for the translocation of thiamine across the membrane. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213265 [Multi-domain] Cd Length: 211 Bit Score: 153.80 E-value: 1.30e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 2 ITLKNVSKWYGHFQVLTDCSTEVKKGEVVVvcGPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVndkkTDLAKLRSRVGM 81
Cdd:cd03298 1 VRLDKIRFSYGEQPMHFDLTFAQGEITAIV--GPSGSGKSTLLNLIAGFETPQSGRVLINGVDV----TAAPPADRPVSM 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 82 VFQHFELFPHLSIIENLTLAQVKVLKRNkAPAREKALKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMDPIAMLFD 161
Cdd:cd03298 75 LFQENNLFAHLTVEQNVGLGLSPGLKLT-AEDRQAIEVALARVGLAGLEKRLPGELSGGERQRVALARVLVRDKPVLLLD 153
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 446554041 162 EPTSALDPEMINEVLDVMVELANE-GMTMMVVTHEMGFARKVANRVIFMDEGKIIED 217
Cdd:cd03298 154 EPFAALDPALRAEMLDLVLDLHAEtKMTVLMVTHQPEDAKRLAQRVVFLDNGRIAAQ 210
|
|
| AppF |
COG4608 |
ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism]; ... |
34-228 |
2.49e-46 |
|
ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443658 [Multi-domain] Cd Length: 329 Bit Score: 156.82 E-value: 2.49e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVND-KKTDLAKLRSRVGMVFQHfelfPHLS---------II-ENLTLAQ 102
Cdd:COG4608 51 GESGCGKSTLGRLLLRLEEPTSGEILFDGQDITGlSGRELRPLRRRMQMVFQD----PYASlnprmtvgdIIaEPLRIHG 126
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 103 VKvlkrNKAPAREKALKLLERVGLSA-HANKFPAQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLDVMVE 181
Cdd:COG4608 127 LA----SKAERRERVAELLELVGLRPeHADRYPHEFSGGQRQRIGIARALALNPKLIVCDEPVSALDVSIQAQVLNLLED 202
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 446554041 182 LANE-GMTMMVVTHEMGFARKVANRVIFMDEGKIIEDSPKDAFFDNPK 228
Cdd:COG4608 203 LQDElGLTYLFISHDLSVVRHISDRVAVMYLGKIVEIAPRDELYARPL 250
|
|
| ABC_ModC_molybdenum_transporter |
cd03297 |
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type ... |
34-218 |
4.11e-46 |
|
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213264 [Multi-domain] Cd Length: 214 Bit Score: 152.83 E-value: 4.11e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVND--KKTDLAKLRSRVGMVFQHFELFPHLSIIENLTLAqvkvLKRNK- 110
Cdd:cd03297 30 GASGAGKSTLLRCIAGLEKPDGGTIVLNGTVLFDsrKKINLPPQQRKIGLVFQQYALFPHLNVRENLAFG----LKRKRn 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 111 APAREKALKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLDVMVEL-ANEGMTM 189
Cdd:cd03297 106 REDRISVDELLDLLGLDHLLNRYPAQLSGGEKQRVALARALAAQPELLLLDEPFSALDRALRLQLLPELKQIkKNLNIPV 185
|
170 180
....*....|....*....|....*....
gi 446554041 190 MVVTHEMGFARKVANRVIFMDEGKIIEDS 218
Cdd:cd03297 186 IFVTHDLSEAEYLADRIVVMEDGRLQYIG 214
|
|
| ABC_MalK_N |
cd03301 |
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) ... |
2-214 |
8.03e-46 |
|
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) proteins function from bacteria to human, mediating the translocation of substances into and out of cells or organelles. ABC transporters contain two transmembrane-spanning domains (TMDs) or subunits and two nucleotide binding domains (NBDs) or subunits that couple transport to the hydrolysis of ATP. In the maltose transport system, the periplasmic maltose binding protein (MBP) stimulates the ATPase activity of the membrane-associated transporter, which consists of two transmembrane subunits, MalF and MalG, and two copies of the ATP binding subunit, MalK, and becomes tightly bound to the transporter in the catalytic transition state, ensuring that maltose is passed to the transporter as ATP is hydrolyzed.
Pssm-ID: 213268 [Multi-domain] Cd Length: 213 Bit Score: 152.02 E-value: 8.03e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 2 ITLKNVSKWYGHFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVND---KKTDLAklrsr 78
Cdd:cd03301 1 VELENVTKRFGNVTALDDLNLDIADGEFVVLLGPSGCGKTTTLRMIAGLEEPTSGRIYIGGRDVTDlppKDRDIA----- 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 79 vgMVFQHFELFPHLSIIENLTLAqVKVLKRNKAPAREKALKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMDPIAM 158
Cdd:cd03301 76 --MVFQNYALYPHMTVYDNIAFG-LKLRKVPKDEIDERVREVAELLQIEHLLDRKPKQLSGGQRQRVALGRAIVREPKVF 152
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 159 LFDEPTSALDP----EMINEVLDVMVELaneGMTMMVVTHEMGFARKVANRVIFMDEGKI 214
Cdd:cd03301 153 LMDEPLSNLDAklrvQMRAELKRLQQRL---GTTTIYVTHDQVEAMTMADRIAVMNDGQI 209
|
|
| fbpC |
PRK11432 |
ferric ABC transporter ATP-binding protein; |
4-229 |
1.04e-45 |
|
ferric ABC transporter ATP-binding protein;
Pssm-ID: 183133 [Multi-domain] Cd Length: 351 Bit Score: 155.65 E-value: 1.04e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 4 LKNVSKWYGHFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVndkkTDLAKLRSRVGMVF 83
Cdd:PRK11432 9 LKNITKRFGSNTVIDNLNLTIKQGTMVTLLGPSGCGKTTVLRLVAGLEKPTEGQIFIDGEDV----THRSIQQRDICMVF 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 84 QHFELFPHLSIIENLTLAqVKVLKRNKAPAREKALKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMDPIAMLFDEP 163
Cdd:PRK11432 85 QSYALFPHMSLGENVGYG-LKMLGVPKEERKQRVKEALELVDLAGFEDRYVDQISGGQQQRVALARALILKPKVLLFDEP 163
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446554041 164 TSALDPEMINEVLDVMVELANE-GMTMMVVTHEMGFARKVANRVIFMDEGKIIEDSPKDAFFDNPKS 229
Cdd:PRK11432 164 LSNLDANLRRSMREKIRELQQQfNITSLYVTHDQSEAFAVSDTVIVMNKGKIMQIGSPQELYRQPAS 230
|
|
| ABC_ATPase |
cd00267 |
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large ... |
3-213 |
2.72e-44 |
|
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213179 [Multi-domain] Cd Length: 157 Bit Score: 146.24 E-value: 2.72e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 3 TLKNVSKWYGHFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVNDKktDLAKLRSRVGMV 82
Cdd:cd00267 1 EIENLSFRYGGRTALDNVSLTLKAGEIVALVGPNGSGKSTLLRAIAGLLKPTSGEILIDGKDIAKL--PLEELRRRIGYV 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 83 FQhfelfphlsiienltlaqvkvlkrnkaparekalkllervglsahankfpaqLSGGQQQRVAIARALCMDPIAMLFDE 162
Cdd:cd00267 79 PQ----------------------------------------------------LSGGQRQRVALARALLLNPDLLLLDE 106
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 446554041 163 PTSALDPEMINEVLDVMVELANEGMTMMVVTHEMGFARKVANRVIFMDEGK 213
Cdd:cd00267 107 PTSGLDPASRERLLELLRELAEEGRTVIIVTHDPELAELAADRVIVLKDGK 157
|
|
| LivF |
COG0410 |
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid ... |
1-228 |
4.63e-44 |
|
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid transport and metabolism];
Pssm-ID: 440179 [Multi-domain] Cd Length: 236 Bit Score: 148.21 E-value: 4.63e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 1 MITLKNVSKWYGHFQVLTDCS--------TevkkgevvvvC--GPSGSGKSTLIKTVNGLEPVQQGEITVDGivvndkkT 70
Cdd:COG0410 3 MLEVENLHAGYGGIHVLHGVSleveegeiV----------AllGRNGAGKTTLLKAISGLLPPRSGSIRFDG-------E 65
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 71 DLAKL----RSRVGMVF--QHFELFPHLSIIENLTLAQVKVLKRNKAPAR-EKAL----KLLERVGLSAhankfpAQLSG 139
Cdd:COG0410 66 DITGLpphrIARLGIGYvpEGRRIFPSLTVEENLLLGAYARRDRAEVRADlERVYelfpRLKERRRQRA------GTLSG 139
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 140 GQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLDVMVELANEGMTMMVVTHEMGFARKVANRVIFMDEGKIIEDSP 219
Cdd:COG0410 140 GEQQMLAIGRALMSRPKLLLLDEPSLGLAPLIVEEIFEIIRRLNREGVTILLVEQNARFALEIADRAYVLERGRIVLEGT 219
|
....*....
gi 446554041 220 KDAFFDNPK 228
Cdd:COG0410 220 AAELLADPE 228
|
|
| ABCC_MRP_Like |
cd03228 |
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP ... |
2-213 |
5.93e-44 |
|
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP (Multidrug Resistance Protein)-like transporters are involved in drug, peptide, and lipid export. They belong to the subfamily C of the ATP-binding cassette (ABC) superfamily of transport proteins. The ABCC subfamily contains transporters with a diverse functional spectrum that includes ion transport, cell surface receptor, and toxin secretion activities. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains, each composed of six transmembrane (TM) helices, and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213195 [Multi-domain] Cd Length: 171 Bit Score: 145.60 E-value: 5.93e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 2 ITLKNVSKWYGHF--QVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQQGEITVDGIvvNDKKTDLAKLRSRV 79
Cdd:cd03228 1 IEFKNVSFSYPGRpkPVLKDVSLTIKPGEKVAIVGPSGSGKSTLLKLLLRLYDPTSGEILIDGV--DLRDLDLESLRKNI 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 80 GMVFQHFELFpHLSIIENLtlaqvkvlkrnkaparekalkllervglsahankfpaqLSGGQQQRVAIARALCMDPIAML 159
Cdd:cd03228 79 AYVPQDPFLF-SGTIRENI--------------------------------------LSGGQRQRIAIARALLRDPPILI 119
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 446554041 160 FDEPTSALDPEMINEVLDVMVELAnEGMTMMVVTHEMGFARKvANRVIFMDEGK 213
Cdd:cd03228 120 LDEATSALDPETEALILEALRALA-KGKTVIVIAHRLSTIRD-ADRIIVLDDGR 171
|
|
| ABC_ModC_like |
cd03299 |
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely ... |
34-236 |
1.09e-43 |
|
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely related to ModC. ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213266 [Multi-domain] Cd Length: 235 Bit Score: 147.10 E-value: 1.09e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVndkkTDLAKLRSRVGMVFQHFELFPHLSIIENLTLAqVKVLKRNKAPA 113
Cdd:cd03299 32 GPTGSGKSVLLETIAGFIKPDSGKILLNGKDI----TNLPPEKRDISYVPQNYALFPHMTVYKNIAYG-LKKRKVDKKEI 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 114 REKALKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEmINEVLDVMVELA--NEGMTMMV 191
Cdd:cd03299 107 ERKVLEIAEMLGIDHLLNRKPETLSGGEQQRVAIARALVVNPKILLLDEPFSALDVR-TKEKLREELKKIrkEFGVTVLH 185
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 446554041 192 VTHEMGFARKVANRVIFMDEGKIIEDSPKDAFFDNPKSDRAKDFL 236
Cdd:cd03299 186 VTHDFEEAWALADKVAIMLNGKLIQVGKPEEVFKKPKNEFVAEFL 230
|
|
| PRK14247 |
PRK14247 |
phosphate ABC transporter ATP-binding protein; Provisional |
2-230 |
1.28e-43 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172735 [Multi-domain] Cd Length: 250 Bit Score: 147.37 E-value: 1.28e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 2 ITLKNVSKWYGHFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGL-----EPVQQGEITVDGIVVNdkKTDLAKLR 76
Cdd:PRK14247 4 IEIRDLKVSFGQVEVLDGVNLEIPDNTITALMGPSGSGKSTLLRVFNRLielypEARVSGEVYLDGQDIF--KMDVIELR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 77 SRVGMVFQHFELFPHLSIIENLTLA-QVKVLKRNKAPAREKALKLLERVGL----SAHANKFPAQLSGGQQQRVAIARAL 151
Cdd:PRK14247 82 RRVQMVFQIPNPIPNLSIFENVALGlKLNRLVKSKKELQERVRWALEKAQLwdevKDRLDAPAGKLSGGQQQRLCIARAL 161
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446554041 152 CMDPIAMLFDEPTSALDPEMINEVLDVMVELANEgMTMMVVTHEMGFARKVANRVIFMDEGKIIEDSPKDAFFDNPKSD 230
Cdd:PRK14247 162 AFQPEVLLADEPTANLDPENTAKIESLFLELKKD-MTIVLVTHFPQQAARISDYVAFLYKGQIVEWGPTREVFTNPRHE 239
|
|
| potA |
PRK09452 |
spermidine/putrescine ABC transporter ATP-binding protein PotA; |
2-221 |
1.30e-43 |
|
spermidine/putrescine ABC transporter ATP-binding protein PotA;
Pssm-ID: 236523 [Multi-domain] Cd Length: 375 Bit Score: 150.87 E-value: 1.30e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 2 ITLKNVSKWYGHFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVndkkTDLAKLRSRVGM 81
Cdd:PRK09452 15 VELRGISKSFDGKEVISNLDLTINNGEFLTLLGPSGCGKTTVLRLIAGFETPDSGRIMLDGQDI----THVPAENRHVNT 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 82 VFQHFELFPHLSIIENLTLAqvkvLKRNKAPARE------KALKLlerVGLSAHANKFPAQLSGGQQQRVAIARALCMDP 155
Cdd:PRK09452 91 VFQSYALFPHMTVFENVAFG----LRMQKTPAAEitprvmEALRM---VQLEEFAQRKPHQLSGGQQQRVAIARAVVNKP 163
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446554041 156 IAMLFDEPTSALD----PEMINEVLDVMVELaneGMTMMVVTHEMGFARKVANRVIFMDEGKIIED-SPKD 221
Cdd:PRK09452 164 KVLLLDESLSALDyklrKQMQNELKALQRKL---GITFVFVTHDQEEALTMSDRIVVMRDGRIEQDgTPRE 231
|
|
| potA |
TIGR01187 |
spermidine/putrescine ABC transporter ATP-binding subunit; This model describes spermidine ... |
34-239 |
3.06e-42 |
|
spermidine/putrescine ABC transporter ATP-binding subunit; This model describes spermidine/putrescine ABC transporter, ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. Polyamines like spermidine and putrescine play vital role in cell proliferation, differentiation, and ion homeostasis. The concentration of polyamines within the cell are regulated by biosynthesis, degradation and transport (uptake and efflux included). [Transport and binding proteins, Amino acids, peptides and amines]
Pssm-ID: 162242 [Multi-domain] Cd Length: 325 Bit Score: 146.10 E-value: 3.06e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVndkkTDLAKLRSRVGMVFQHFELFPHLSIIENLTLAqVKVLKRNKAPA 113
Cdd:TIGR01187 3 GPSGCGKTTLLRLLAGFEQPDSGSIMLDGEDV----TNVPPHLRHINMVFQSYALFPHMTVEENVAFG-LKMRKVPRAEI 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 114 REKALKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMDPIAMLFDEPTSALD----PEMINEVLDVMVELaneGMTM 189
Cdd:TIGR01187 78 KPRVLEALRLVQLEEFADRKPHQLSGGQQQRVALARALVFKPKILLLDEPLSALDkklrDQMQLELKTIQEQL---GITF 154
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 446554041 190 MVVTHEMGFARKVANRVIFMDEGKIIEDSPKDAFFDNPKSDRAKDFLAKI 239
Cdd:TIGR01187 155 VFVTHDQEEAMTMSDRIAIMRKGKIAQIGTPEEIYEEPANLFVARFIGEI 204
|
|
| thiQ |
PRK10771 |
thiamine ABC transporter ATP-binding protein ThiQ; |
1-222 |
4.80e-42 |
|
thiamine ABC transporter ATP-binding protein ThiQ;
Pssm-ID: 182716 [Multi-domain] Cd Length: 232 Bit Score: 142.80 E-value: 4.80e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 1 MITLKNVSKWYGHFQVLTDCSTEVKKGEVVVvcGPSGSGKSTLIKTVNGLEPVQQGEITVDGIvvNDKKTDLAKlrsR-V 79
Cdd:PRK10771 1 MLKLTDITWLYHHLPMRFDLTVERGERVAIL--GPSGAGKSTLLNLIAGFLTPASGSLTLNGQ--DHTTTPPSR---RpV 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 80 GMVFQHFELFPHLSIIENLTLAQVKVLKRNKApAREKALKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMD-PIaM 158
Cdd:PRK10771 74 SMLFQENNLFSHLTVAQNIGLGLNPGLKLNAA-QREKLHAIARQMGIEDLLARLPGQLSGGQRQRVALARCLVREqPI-L 151
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446554041 159 LFDEPTSALDPEMINEVLDVMVELANE-GMTMMVVTHEMGFARKVANRVIFMDEGKIIEDSPKDA 222
Cdd:PRK10771 152 LLDEPFSALDPALRQEMLTLVSQVCQErQLTLLMVSHSLEDAARIAPRSLVVADGRIAWDGPTDE 216
|
|
| CydC |
COG4987 |
ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease ... |
34-216 |
5.83e-42 |
|
ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444011 [Multi-domain] Cd Length: 569 Bit Score: 149.92 E-value: 5.83e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVNDkkTDLAKLRSRVGMVFQHFELFpHLSIIENLTLAqvkvlkrNKAPA 113
Cdd:COG4987 368 GPSGSGKSTLLALLLRFLDPQSGSITLGGVDLRD--LDEDDLRRRIAVVPQRPHLF-DTTLRENLRLA-------RPDAT 437
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 114 REKALKLLERVGLSAHANKFP-----------AQLSGGQQQRVAIARALCMD-PIaMLFDEPTSALDPEMINEVLDVMVE 181
Cdd:COG4987 438 DEELWAALERVGLGDWLAALPdgldtwlgeggRRLSGGERRRLALARALLRDaPI-LLLDEPTEGLDAATEQALLADLLE 516
|
170 180 190
....*....|....*....|....*....|....*.
gi 446554041 182 LAnEGMTMMVVTHEM-GFARkvANRVIFMDEGKIIE 216
Cdd:COG4987 517 AL-AGRTVLLITHRLaGLER--MDRILVLEDGRIVE 549
|
|
| ABC_Iron-Siderophores_B12_Hemin |
cd03214 |
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related ... |
3-215 |
7.02e-42 |
|
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; ABC transporters, involved in the uptake of siderophores, heme, and vitamin B12, are widely conserved in bacteria and archaea. Only very few species lack representatives of the siderophore family transporters. The E. coli BtuCD protein is an ABC transporter mediating vitamin B12 uptake. The two ATP-binding cassettes (BtuD) are in close contact with each other, as are the two membrane-spanning subunits (BtuC); this arrangement is distinct from that observed for the E. coli lipid flippase MsbA. The BtuC subunits provide 20 transmembrane helices grouped around a translocation pathway that is closed to the cytoplasm by a gate region, whereas the dimer arrangement of the BtuD subunits resembles the ATP-bound form of the Rad50 DNA repair enzyme. A prominent cytoplasmic loop of BtuC forms the contact region with the ATP-binding cassette and represent a conserved motif among the ABC transporters.
Pssm-ID: 213181 [Multi-domain] Cd Length: 180 Bit Score: 140.65 E-value: 7.02e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 3 TLKNVSKWYGHFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQQGEITVDGivvndkkTDLAKLRSRvgmv 82
Cdd:cd03214 1 EVENLSVGYGGRTVLDDLSLSIEAGEIVGILGPNGAGKSTLLKTLAGLLKPSSGEILLDG-------KDLASLSPK---- 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 83 fqhfELFPHLSIienltLAQVkvlkrnkaparekalklLERVGLSAHANKFPAQLSGGQQQRVAIARALCMDPIAMLFDE 162
Cdd:cd03214 70 ----ELARKIAY-----VPQA-----------------LELLGLAHLADRPFNELSGGERQRVLLARALAQEPPILLLDE 123
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 446554041 163 PTSALDPEMINEVLDVMVELANE-GMTMMVVTHEMGFARKVANRVIFMDEGKII 215
Cdd:cd03214 124 PTSHLDIAHQIELLELLRRLARErGKTVVMVLHDLNLAARYADRVILLKDGRIV 177
|
|
| ABC_tran |
pfam00005 |
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ... |
34-165 |
7.30e-42 |
|
ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.
Pssm-ID: 394964 [Multi-domain] Cd Length: 150 Bit Score: 139.71 E-value: 7.30e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVNDKktDLAKLRSRVGMVFQHFELFPHLSIIENLTLAqVKVLKRNKAPA 113
Cdd:pfam00005 18 GPNGAGKSTLLKLIAGLLSPTEGTILLDGQDLTDD--ERKSLRKEIGYVFQDPQLFPRLTVRENLRLG-LLLKGLSKREK 94
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*.
gi 446554041 114 REKALKLLERVGLSA----HANKFPAQLSGGQQQRVAIARALCMDPIAMLFDEPTS 165
Cdd:pfam00005 95 DARAEEALEKLGLGDladrPVGERPGTLSGGQRQRVAIARALLTKPKLLLLDEPTA 150
|
|
| PRK14267 |
PRK14267 |
phosphate ABC transporter ATP-binding protein; Provisional |
2-240 |
8.54e-42 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 184596 [Multi-domain] Cd Length: 253 Bit Score: 142.67 E-value: 8.54e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 2 ITLKNVSKWYGHFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGL-----EPVQQGEITVDGIVVNDKKTDLAKLR 76
Cdd:PRK14267 5 IETVNLRVYYGSNHVIKGVDLKIPQNGVFALMGPSGCGKSTLLRTFNRLlelneEARVEGEVRLFGRNIYSPDVDPIEVR 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 77 SRVGMVFQHFELFPHLSIIENLTLAqvkvLKRNKAPAREKALKLLERVGLSAHA---------NKFPAQLSGGQQQRVAI 147
Cdd:PRK14267 85 REVGMVFQYPNPFPHLTIYDNVAIG----VKLNGLVKSKKELDERVEWALKKAAlwdevkdrlNDYPSNLSGGQRQRLVI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 148 ARALCMDPIAMLFDEPTSALDPEMINEVLDVMVELANEgMTMMVVTHEMGFARKVANRVIFMDEGKIIEDSPKDAFFDNP 227
Cdd:PRK14267 161 ARALAMKPKILLMDEPTANIDPVGTAKIEELLFELKKE-YTIVLVTHSPAQAARVSDYVAFLYLGKLIEVGPTRKVFENP 239
|
250
....*....|...
gi 446554041 228 KSDRAKDFLAKIL 240
Cdd:PRK14267 240 EHELTEKYVTGAL 252
|
|
| MdlB |
COG1132 |
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms]; |
34-216 |
1.99e-41 |
|
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];
Pssm-ID: 440747 [Multi-domain] Cd Length: 579 Bit Score: 148.77 E-value: 1.99e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVNDkkTDLAKLRSRVGMVFQHFELFpHLSIIENLTLAqvkvlkRNKAPa 113
Cdd:COG1132 373 GPSGSGKSTLVNLLLRFYDPTSGRILIDGVDIRD--LTLESLRRQIGVVPQDTFLF-SGTIRENIRYG------RPDAT- 442
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 114 REKALKLLERVGLSAHANKFP-----------AQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEmiNE--VLDVMV 180
Cdd:COG1132 443 DEEVEEAAKAAQAHEFIEALPdgydtvvgergVNLSGGQRQRIAIARALLKDPPILILDEATSALDTE--TEalIQEALE 520
|
170 180 190
....*....|....*....|....*....|....*.
gi 446554041 181 ELAnEGMTMMVVTHEMGFARKvANRVIFMDEGKIIE 216
Cdd:COG1132 521 RLM-KGRTTIVIAHRLSTIRN-ADRILVLDDGRIVE 554
|
|
| PRK14239 |
PRK14239 |
phosphate transporter ATP-binding protein; Provisional |
1-236 |
2.31e-41 |
|
phosphate transporter ATP-binding protein; Provisional
Pssm-ID: 184585 [Multi-domain] Cd Length: 252 Bit Score: 141.84 E-value: 2.31e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 1 MITLKNVSKWYGHFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGL-----EPVQQGEITVDGIVVNDKKTDLAKL 75
Cdd:PRK14239 5 ILQVSDLSVYYNKKKALNSVSLDFYPNEITALIGPSGSGKSTLLRSINRMndlnpEVTITGSIVYNGHNIYSPRTDTVDL 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 76 RSRVGMVFQHFELFPhLSIIEN----LTLAQVKVlKRNKAPAREKALK---LLERVGLSAHANKFpaQLSGGQQQRVAIA 148
Cdd:PRK14239 85 RKEIGMVFQQPNPFP-MSIYENvvygLRLKGIKD-KQVLDEAVEKSLKgasIWDEVKDRLHDSAL--GLSGGQQQRVCIA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 149 RALCMDPIAMLFDEPTSALDPEMINEVLDVMVELANEgMTMMVVTHEMGFARKVANRVIFMDEGKIIEDSPKDAFFDNPK 228
Cdd:PRK14239 161 RVLATSPKIILLDEPTSALDPISAGKIEETLLGLKDD-YTMLLVTRSMQQASRISDRTGFFLDGDLIEYNDTKQMFMNPK 239
|
....*...
gi 446554041 229 SDRAKDFL 236
Cdd:PRK14239 240 HKETEDYI 247
|
|
| ABC_BcrA_bacitracin_resist |
cd03268 |
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily ... |
2-217 |
2.35e-41 |
|
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily represents ABC transporters involved in peptide antibiotic resistance. Bacitracin is a dodecapeptide antibiotic produced by B. licheniformis and B. subtilis. The synthesis of bacitracin is non-ribosomally catalyzed by a multi-enzyme complex BcrABC. Bacitracin has potent antibiotic activity against gram-positive bacteria. The inhibition of peptidoglycan biosynthesis is the best characterized bacterial effect of bacitracin. The bacitracin resistance of B. licheniformis is mediated by the ABC transporter Bcr which is composed of two identical BcrA ATP-binding subunits and one each of the integral membrane proteins, BcrB and BcrC. B. subtilis cells carrying bcr genes on high-copy number plasmids develop collateral detergent sensitivity, a similar phenomenon in human cells with overexpressed multi-drug resistance P-glycoprotein.
Pssm-ID: 213235 [Multi-domain] Cd Length: 208 Bit Score: 140.43 E-value: 2.35e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 2 ITLKNVSKWYGHFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQQGEITVDGivvnDKKTDLAKLRSRVGM 81
Cdd:cd03268 1 LKTNDLTKTYGKKRVLDDISLHVKKGEIYGFLGPNGAGKTTTMKIILGLIKPDSGEITFDG----KSYQKNIEALRRIGA 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 82 VFQHFELFPHLSIIENLTLAQVKVLKRNKapareKALKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMDPIAMLFD 161
Cdd:cd03268 77 LIEAPGFYPNLTARENLRLLARLLGIRKK-----RIDEVLDVVGLKDSAKKKVKGFSLGMKQRLGIALALLGNPDLLILD 151
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 446554041 162 EPTSALDPEMINEVLDVMVELANEGMTMMVVTHEMGFARKVANRVIFMDEGKIIED 217
Cdd:cd03268 152 EPTNGLDPDGIKELRELILSLRDQGITVLISSHLLSEIQKVADRIGIINKGKLIEE 207
|
|
| YejF |
COG4172 |
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ... |
34-230 |
2.74e-41 |
|
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 443332 [Multi-domain] Cd Length: 533 Bit Score: 147.52 E-value: 2.74e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEPvQQGEITVDGIVVND-KKTDLAKLRSRVGMVFQH-F-ELFPHLS----IIENLTLAQVKVl 106
Cdd:COG4172 319 GESGSGKSTLGLALLRLIP-SEGEIRFDGQDLDGlSRRALRPLRRRMQVVFQDpFgSLSPRMTvgqiIAEGLRVHGPGL- 396
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 107 krNKAPAREKALKLLERVGLS-AHANKFPAQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLDVMVELANE 185
Cdd:COG4172 397 --SAAERRARVAEALEEVGLDpAARHRYPHEFSGGQRQRIAIARALILEPKLLVLDEPTSALDVSVQAQILDLLRDLQRE 474
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 446554041 186 -GMTMMVVTHEMGFARKVANRVIFMDEGKIIEDSPKDAFFDNPKSD 230
Cdd:COG4172 475 hGLAYLFISHDLAVVRALAHRVMVMKDGKVVEQGPTEQVFDAPQHP 520
|
|
| CcmA |
COG4133 |
ABC-type transport system involved in cytochrome c biogenesis, ATPase component ... |
1-195 |
8.92e-41 |
|
ABC-type transport system involved in cytochrome c biogenesis, ATPase component [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 443308 [Multi-domain] Cd Length: 206 Bit Score: 138.77 E-value: 8.92e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 1 MITLKNVSKWYGHFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQQGEITVDGIvvnDKKTDLAKLRSRVG 80
Cdd:COG4133 2 MLEAENLSCRRGERLLFSGLSFTLAAGEALALTGPNGSGKTTLLRILAGLLPPSAGEVLWNGE---PIRDAREDYRRRLA 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 81 MVFQHFELFPHLSIIENLTLAQvKVlkRNKAPAREKALKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMDPIAMLF 160
Cdd:COG4133 79 YLGHADGLKPELTVRENLRFWA-AL--YGLRADREAIDEALEAVGLAGLADLPVRQLSAGQKRRVALARLLLSPAPLWLL 155
|
170 180 190
....*....|....*....|....*....|....*
gi 446554041 161 DEPTSALDPEMINEVLDVMVELANEGMTMMVVTHE 195
Cdd:COG4133 156 DEPFTALDAAGVALLAELIAAHLARGGAVLLTTHQ 190
|
|
| ABC_cobalt_CbiO_domain2 |
cd03226 |
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of ... |
34-215 |
1.94e-40 |
|
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. The CbiMNQO family ABC transport system is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.
Pssm-ID: 213193 [Multi-domain] Cd Length: 205 Bit Score: 137.77 E-value: 1.94e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEPVQQGEITVDGivvndKKTDLAKLRSRVGMVFQH--FELFPHlSIIENLTLAqvkvlKRNKA 111
Cdd:cd03226 33 GKNGAGKTTLAKILAGLIKESSGSILLNG-----KPIKAKERRKSIGYVMQDvdYQLFTD-SVREELLLG-----LKELD 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 112 PAREKALKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLDVMVELANEGMTMMV 191
Cdd:cd03226 102 AGNEQAETVLKDLDLYALKERHPLSLSGGQKQRLAIAAALLSGKDLLIFDEPTSGLDYKNMERVGELIRELAAQGKAVIV 181
|
170 180
....*....|....*....|....
gi 446554041 192 VTHEMGFARKVANRVIFMDEGKII 215
Cdd:cd03226 182 ITHDYEFLAKVCDRVLLLANGAIV 205
|
|
| modC_ABC |
TIGR02142 |
molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding ... |
6-222 |
2.01e-40 |
|
molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding cassette (ABC) protein of the three subunit molybdate ABC transporter. The three proteins of this complex are homologous to proteins of the sulfate ABC transporter. Molybdenum may be used in nitrogenases of nitrogen-fixing bacteria and in molybdopterin cofactors. In some cases, molybdate may be transported by a sulfate transporter rather than by a specific molybdate transporter. [Transport and binding proteins, Anions]
Pssm-ID: 131197 [Multi-domain] Cd Length: 354 Bit Score: 141.79 E-value: 2.01e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 6 NVSKWYGHFQVltDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVND--KKTDLAKLRSRVGMVF 83
Cdd:TIGR02142 4 RFSKRLGDFSL--DADFTLPGQGVTAIFGRSGSGKTTLIRLIAGLTRPDEGEIVLNGRTLFDsrKGIFLPPEKRRIGYVF 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 84 QHFELFPHLSIIENLT--LAQVKVLKRNKAPARekalkLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMDPIAMLFD 161
Cdd:TIGR02142 82 QEARLFPHLSVRGNLRygMKRARPSERRISFER-----VIELLGIGHLLGRLPGRLSGGEKQRVAIGRALLSSPRLLLMD 156
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446554041 162 EPTSALDPEMINEVLDVMVELANE-GMTMMVVTHEMGFARKVANRVIFMDEGKIIEDSPKDA 222
Cdd:TIGR02142 157 EPLAALDDPRKYEILPYLERLHAEfGIPILYVSHSLQEVLRLADRVVVLEDGRVAAAGPIAE 218
|
|
| ssuB |
PRK11247 |
aliphatic sulfonates transport ATP-binding subunit; Provisional |
2-221 |
2.49e-40 |
|
aliphatic sulfonates transport ATP-binding subunit; Provisional
Pssm-ID: 183055 [Multi-domain] Cd Length: 257 Bit Score: 139.04 E-value: 2.49e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 2 ITLKNVSKWYGHFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQQGEITVDgivvndkKTDLAKLRSRVGM 81
Cdd:PRK11247 13 LLLNAVSKRYGERTVLNQLDLHIPAGQFVAVVGRSGCGKSTLLRLLAGLETPSAGELLAG-------TAPLAEAREDTRL 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 82 VFQHFELFPHLSIIENLTLAqvkvLKRNkapAREKALKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMDPIAMLFD 161
Cdd:PRK11247 86 MFQDARLLPWKKVIDNVGLG----LKGQ---WRDAALQALAAVGLADRANEWPAALSGGQKQRVALARALIHRPGLLLLD 158
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446554041 162 EPTSALDPEMINEVLDVMVELANE-GMTMMVVTHEMGFARKVANRVIFMDEGKIIEDSPKD 221
Cdd:PRK11247 159 EPLGALDALTRIEMQDLIESLWQQhGFTVLLVTHDVSEAVAMADRVLLIEEGKIGLDLTVD 219
|
|
| cbiO |
PRK13641 |
energy-coupling factor transporter ATPase; |
34-225 |
2.53e-40 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237456 [Multi-domain] Cd Length: 287 Bit Score: 139.96 E-value: 2.53e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEPVQQGEITVDG--IVVNDKKTDLAKLRSRVGMVFQhfelFPHLSIIENLTLAQVKVLKRN-- 109
Cdd:PRK13641 40 GHTGSGKSTLMQHFNALLKPSSGTITIAGyhITPETGNKNLKKLRKKVSLVFQ----FPEAQLFENTVLKDVEFGPKNfg 115
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 110 --KAPAREKALKLLERVGLSAH-ANKFPAQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLDVMVELANEG 186
Cdd:PRK13641 116 fsEDEAKEKALKWLKKVGLSEDlISKSPFELSGGQMRRVAIAGVMAYEPEILCLDEPAAGLDPEGRKEMMQLFKDYQKAG 195
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 446554041 187 MTMMVVTHEMGFARKVANRVIFMDEGKIIE-DSPKDAFFD 225
Cdd:PRK13641 196 HTVILVTHNMDDVAEYADDVLVLEHGKLIKhASPKEIFSD 235
|
|
| CydD |
COG4988 |
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease ... |
34-216 |
4.27e-40 |
|
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444012 [Multi-domain] Cd Length: 563 Bit Score: 144.90 E-value: 4.27e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVNDkkTDLAKLRSRVGMVFQHFELFpHLSIIENLTLAqvkvlkrNKAPA 113
Cdd:COG4988 370 GPSGAGKSTLLNLLLGFLPPYSGSILINGVDLSD--LDPASWRRQIAWVPQNPYLF-AGTIRENLRLG-------RPDAS 439
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 114 REKALKLLERVGLSAHANKFP-----------AQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLDVMVEL 182
Cdd:COG4988 440 DEELEAALEAAGLDEFVAALPdgldtplgeggRGLSGGQAQRLALARALLRDAPLLLLDEPTAHLDAETEAEILQALRRL 519
|
170 180 190
....*....|....*....|....*....|....
gi 446554041 183 AnEGMTMMVVTHEMGFARKvANRVIFMDEGKIIE 216
Cdd:COG4988 520 A-KGRTVILITHRLALLAQ-ADRILVLDDGRIVE 551
|
|
| thiQ |
TIGR01277 |
thiamine ABC transporter, ATP-binding protein; This model describes the energy-transducing ... |
34-214 |
5.72e-40 |
|
thiamine ABC transporter, ATP-binding protein; This model describes the energy-transducing ATPase subunit ThiQ of the ThiBPQ thiamine (and thiamine pyrophosphate) ABC transporter in several Proteobacteria. This protein is found so far only in Proteobacteria, and is found in complete genomes only if the ThiB and ThiP subunits are also found. [Transport and binding proteins, Other]
Pssm-ID: 130344 [Multi-domain] Cd Length: 213 Bit Score: 136.91 E-value: 5.72e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVndkkTDLAKLRSRVGMVFQHFELFPHLSIIENLTLAQVKVLKRNkAPA 113
Cdd:TIGR01277 31 GPSGAGKSTLLNLIAGFIEPASGSIKVNDQSH----TGLAPYQRPVSMLFQENNLFAHLTVRQNIGLGLHPGLKLN-AEQ 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 114 REKALKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLDVMVELANE-GMTMMVV 192
Cdd:TIGR01277 106 QEKVVDAAQQVGIADYLDRLPEQLSGGQRQRVALARCLVRPNPILLLDEPFSALDPLLREEMLALVKQLCSErQRTLLMV 185
|
170 180
....*....|....*....|..
gi 446554041 193 THEMGFARKVANRVIFMDEGKI 214
Cdd:TIGR01277 186 THHLSDARAIASQIAVVSQGKI 207
|
|
| ABC_ATP_DarD |
NF038007 |
darobactin export ABC transporter ATP-binding protein; |
1-214 |
6.58e-40 |
|
darobactin export ABC transporter ATP-binding protein;
Pssm-ID: 411600 [Multi-domain] Cd Length: 218 Bit Score: 136.77 E-value: 6.58e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 1 MITLKNVSKWYG----HFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQQGEITVDGI-VVNDKKTDLAKL 75
Cdd:NF038007 1 MLNMQNAEKCYItktiKTKVLNHLNFSVEKGDFVSIMGPSGSGKSTLLNIIGMFDSLDSGSLTLAGKeVTNLSYSQKIIL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 76 RSR-VGMVFQHFELFPHLSIIENLTLAqVKVLKRNKAPAREKALKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMD 154
Cdd:NF038007 81 RRElIGYIFQSFNLIPHLSIFDNVALP-LKYRGVAKKERIERVNQVLNLFGIDNRRNHKPMQLSGGQQQRVAIARAMVSN 159
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 155 PIAMLFDEPTSALDPEMINEVLDVMVELANEGMTMMVVTHEMGfARKVANRVIFMDEGKI 214
Cdd:NF038007 160 PALLLADEPTGNLDSKNARAVLQQLKYINQKGTTIIMVTHSDE-ASTYGNRIINMKDGKL 218
|
|
| cbiO |
PRK13637 |
energy-coupling factor transporter ATPase; |
34-226 |
1.51e-39 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237455 [Multi-domain] Cd Length: 287 Bit Score: 137.87 E-value: 1.51e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVNDKKTDLAKLRSRVGMVFQH--FELFPhlSIIE--------NLTLAQV 103
Cdd:PRK13637 40 GHTGSGKSTLIQHLNGLLKPTSGKIIIDGVDITDKKVKLSDIRKKVGLVFQYpeYQLFE--ETIEkdiafgpiNLGLSEE 117
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 104 KVLKRNKapareKALKLlerVGLS--AHANKFPAQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLDVMVE 181
Cdd:PRK13637 118 EIENRVK-----RAMNI---VGLDyeDYKDKSPFELSGGQKRRVAIAGVVAMEPKILILDEPTAGLDPKGRDEILNKIKE 189
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 446554041 182 LANE-GMTMMVVTHEMGFARKVANRVIFMDEGKIIEDSPKDAFFDN 226
Cdd:PRK13637 190 LHKEyNMTIILVSHSMEDVAKLADRIIVMNKGKCELQGTPREVFKE 235
|
|
| YejF |
COG4172 |
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ... |
34-230 |
2.01e-39 |
|
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 443332 [Multi-domain] Cd Length: 533 Bit Score: 142.52 E-value: 2.01e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEP----VQQGEITVDGI-VVNDKKTDLAKLR-SRVGMVFQhfE----LFPHLSI----IENLT 99
Cdd:COG4172 43 GESGSGKSVTALSILRLLPdpaaHPSGSILFDGQdLLGLSERELRRIRgNRIAMIFQ--EpmtsLNPLHTIgkqiAEVLR 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 100 LAQvkvlKRNKAPAREKALKLLERVGL---SAHANKFPAQLSGGQQQRVAIARALCMDP---IAmlfDEPTSALDPEMIN 173
Cdd:COG4172 121 LHR----GLSGAAARARALELLERVGIpdpERRLDAYPHQLSGGQRQRVMIAMALANEPdllIA---DEPTTALDVTVQA 193
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 446554041 174 EVLDVMVELANE-GMTMMVVTHEMGFARKVANRVIFMDEGKIIEDSPKDAFFDNPKSD 230
Cdd:COG4172 194 QILDLLKDLQRElGMALLLITHDLGVVRRFADRVAVMRQGEIVEQGPTAELFAAPQHP 251
|
|
| cbiO |
PRK13631 |
cobalt transporter ATP-binding subunit; Provisional |
34-225 |
2.77e-39 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237451 [Multi-domain] Cd Length: 320 Bit Score: 138.06 E-value: 2.77e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVNDKKT--------------DLAKLRSRVGMVFQ--HFELFPHlSIIEN 97
Cdd:PRK13631 59 GNSGSGKSTLVTHFNGLIKSKYGTIQVGDIYIGDKKNnhelitnpyskkikNFKELRRRVSMVFQfpEYQLFKD-TIEKD 137
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 98 LTLAQVKvLKRNKAPAREKALKLLERVGL-SAHANKFPAQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVL 176
Cdd:PRK13631 138 IMFGPVA-LGVKKSEAKKLAKFYLNKMGLdDSYLERSPFGLSGGQKRRVAIAGILAIQPEILIFDEPTAGLDPKGEHEMM 216
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 446554041 177 DVMVELANEGMTMMVVTHEMGFARKVANRVIFMDEGKIIED-SPKDAFFD 225
Cdd:PRK13631 217 QLILDAKANNKTVFVITHTMEHVLEVADEVIVMDKGKILKTgTPYEIFTD 266
|
|
| ABC_drug_resistance_like |
cd03264 |
ABC-type multidrug transport system, ATPase component; The biological function of this family ... |
2-217 |
4.19e-39 |
|
ABC-type multidrug transport system, ATPase component; The biological function of this family is not well characterized, but display ABC domains similar to members of ABCA subfamily. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213231 [Multi-domain] Cd Length: 211 Bit Score: 134.63 E-value: 4.19e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 2 ITLKNVSKWYGHFQVLTDCStEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQQGEITVDGIvvnDKKTDLAKLRSRVGM 81
Cdd:cd03264 1 LQLENLTKRYGKKRALDGVS-LTLGPGMYGLLGPNGAGKTTLMRILATLTPPSSGTIRIDGQ---DVLKQPQKLRRRIGY 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 82 VFQHFELFPHLSIIEnlTLAQVKVLKR-NKAPAREKALKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMDPIAMLF 160
Cdd:cd03264 77 LPQEFGVYPNFTVRE--FLDYIAWLKGiPSKEVKARVDEVLELVNLGDRAKKKIGSLSGGMRRRVGIAQALVGDPSILIV 154
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 446554041 161 DEPTSALDPEMINEVLDVMVELAnEGMTMMVVTHEMGFARKVANRVIFMDEGKIIED 217
Cdd:cd03264 155 DEPTAGLDPEERIRFRNLLSELG-EDRIVILSTHIVEDVESLCNQVAVLNKGKLVFE 210
|
|
| ABC_subfamily_A |
cd03263 |
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily ... |
34-215 |
1.29e-38 |
|
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily mediates the transport of a variety of lipid compounds. Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency, degenerative retinopathies, and congenital keratinization disorders. The ABCA1 protein is involved in disorders of cholesterol transport and high-density lipoprotein (HDL) biosynthesis. The ABCA4 (ABCR) protein transports vitamin A derivatives in the outer segments of photoreceptor cells, and therefore, performs a crucial step in the visual cycle. The ABCA genes are not present in yeast. However, evolutionary studies of ABCA genes indicate that they arose as transporters that subsequently duplicated and that certain sets of ABCA genes were lost in different eukaryotic lineages.
Pssm-ID: 213230 [Multi-domain] Cd Length: 220 Bit Score: 133.40 E-value: 1.29e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEPVQQGEITVDGivvNDKKTDLAKLRSRVGMVFQHFELFPHLSIIENLTL-AQVKVLkrNKAP 112
Cdd:cd03263 35 GHNGAGKTTTLKMLTGELRPTSGTAYING---YSIRTDRKAARQSLGYCPQFDALFDELTVREHLRFyARLKGL--PKSE 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 113 AREKALKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLDVMVELAnEGMTMMVV 192
Cdd:cd03263 110 IKEEVELLLRVLGLTDKANKRARTLSGGMKRKLSLAIALIGGPSVLLLDEPTSGLDPASRRAIWDLILEVR-KGRSIILT 188
|
170 180
....*....|....*....|...
gi 446554041 193 THEMGFARKVANRVIFMDEGKII 215
Cdd:cd03263 189 THSMDEAEALCDRIAIMSDGKLR 211
|
|
| PRK13651 |
PRK13651 |
cobalt transporter ATP-binding subunit; Provisional |
2-217 |
1.29e-38 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184210 [Multi-domain] Cd Length: 305 Bit Score: 135.98 E-value: 1.29e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 2 ITLKNVSKWYG-----HFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQQGEI------------------ 58
Cdd:PRK13651 3 IKVKNIVKIFNkklptELKALDNVSVEINQGEFIAIIGQTGSGKTTFIEHLNALLLPDTGTIewifkdeknkkktkekek 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 59 TVDGIVVndKKTDLAK------LRSRVGMVFQ--HFELFPhlSIIENLTLAQVKVLKRNKAPAREKALKLLERVGLS-AH 129
Cdd:PRK13651 83 VLEKLVI--QKTRFKKikkikeIRRRVGVVFQfaEYQLFE--QTIEKDIIFGPVSMGVSKEEAKKRAAKYIELVGLDeSY 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 130 ANKFPAQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLDVMVELANEGMTMMVVTHEMGFARKVANRVIFM 209
Cdd:PRK13651 159 LQRSPFELSGGQKRRVALAGILAMEPDFLVFDEPTAGLDPQGVKEILEIFDNLNKQGKTIILVTHDLDNVLEWTKRTIFF 238
|
....*...
gi 446554041 210 DEGKIIED 217
Cdd:PRK13651 239 KDGKIIKD 246
|
|
| YnjD |
COG4136 |
ABC-type uncharacterized transport system YnjBCD, ATPase component [General function ... |
34-211 |
2.25e-38 |
|
ABC-type uncharacterized transport system YnjBCD, ATPase component [General function prediction only];
Pssm-ID: 443311 [Multi-domain] Cd Length: 211 Bit Score: 132.61 E-value: 2.25e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNG-LEPV--QQGEITVDGIVVndkkTDLAKLRSRVGMVFQHFELFPHLSIIENLTLAQVKVLKRNK 110
Cdd:COG4136 34 GPSGSGKSTLLAAIAGtLSPAfsASGEVLLNGRRL----TALPAEQRRIGILFQDDLLFPHLSVGENLAFALPPTIGRAQ 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 111 ApaREKALKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLD-VMVELANEGMTM 189
Cdd:COG4136 110 R--RARVEQALEEAGLAGFADRDPATLSGGQRARVALLRALLAEPRALLLDEPFSKLDAALRAQFREfVFEQIRQRGIPA 187
|
170 180
....*....|....*....|..
gi 446554041 190 MVVTHEMGfARKVANRVIFMDE 211
Cdd:COG4136 188 LLVTHDEE-DAPAAGRVLDLGN 208
|
|
| TauB |
COG4525 |
ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism]; |
1-216 |
5.58e-38 |
|
ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443596 [Multi-domain] Cd Length: 262 Bit Score: 133.06 E-value: 5.58e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 1 MITLKNVSKWYG----HFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVNDKKTDlaklr 76
Cdd:COG4525 3 MLTVRHVSVRYPgggqPQPALQDVSLTIESGEFVVALGASGCGKTTLLNLIAGFLAPSSGEITLDGVPVTGPGAD----- 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 77 sRvGMVFQHFELFPHLSIIENLTLAqVKVLKRNKAPAREKALKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMDPI 156
Cdd:COG4525 78 -R-GVVFQKDALLPWLNVLDNVAFG-LRLRGVPKAERRARAEELLALVGLADFARRRIWQLSGGMRQRVGIARALAADPR 154
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446554041 157 AMLFDEPTSALDP---EMINE-VLDVMvelANEGMTMMVVTHEMGFARKVANRVIFMD--EGKIIE 216
Cdd:COG4525 155 FLLMDEPFGALDAltrEQMQElLLDVW---QRTGKGVFLITHSVEEALFLATRLVVMSpgPGRIVE 217
|
|
| cbiO |
PRK13632 |
cobalt transporter ATP-binding subunit; Provisional |
1-239 |
1.08e-37 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237452 [Multi-domain] Cd Length: 271 Bit Score: 132.81 E-value: 1.08e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 1 MITLKNVSKWYG--HFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVNdkKTDLAKLRSR 78
Cdd:PRK13632 7 MIKVENVSFSYPnsENNALKNVSFEINEGEYVAILGHNGSGKSTISKILTGLLKPQSGEIKIDGITIS--KENLKEIRKK 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 79 VGMVFQH---------------FELfphlsiiENltlaqvKVLKRNKAPAreKALKLLERVGLSAHANKFPAQLSGGQQQ 143
Cdd:PRK13632 85 IGIIFQNpdnqfigatveddiaFGL-------EN------KKVPPKKMKD--IIDDLAKKVGMEDYLDKEPQNLSGGQKQ 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 144 RVAIARALCMDPIAMLFDEPTSALDPEMINEVLDVMVELANEGM-TMMVVTHEMGFARKvANRVIFMDEGKII-EDSPKD 221
Cdd:PRK13632 150 RVAIASVLALNPEIIIFDESTSMLDPKGKREIKKIMVDLRKTRKkTLISITHDMDEAIL-ADKVIVFSEGKLIaQGKPKE 228
|
250
....*....|....*...
gi 446554041 222 AFFDnpksdraKDFLAKI 239
Cdd:PRK13632 229 ILNN-------KEILEKA 239
|
|
| cbiO |
PRK13634 |
cobalt transporter ATP-binding subunit; Provisional |
34-225 |
1.25e-37 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237454 [Multi-domain] Cd Length: 290 Bit Score: 133.22 E-value: 1.25e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEPVQQGEITV-DGIVVNDKK-TDLAKLRSRVGMVFQhfelFPHLSIIENLTLAQVKVLKRN-- 109
Cdd:PRK13634 40 GHTGSGKSTLLQHLNGLLQPTSGTVTIgERVITAGKKnKKLKPLRKKVGIVFQ----FPEHQLFEETVEKDICFGPMNfg 115
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 110 --KAPAREKALKLLERVGLSAHA-NKFPAQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLDVMVELANE- 185
Cdd:PRK13634 116 vsEEDAKQKAREMIELVGLPEELlARSPFELSGGQMRRVAIAGVLAMEPEVLVLDEPTAGLDPKGRKEMMEMFYKLHKEk 195
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 446554041 186 GMTMMVVTHEMGFARKVANRVIFMDEGKIIED-SPKDAFFD 225
Cdd:PRK13634 196 GLTTVLVTHSMEDAARYADQIVVMHKGTVFLQgTPREIFAD 236
|
|
| drrA |
TIGR01188 |
daunorubicin resistance ABC transporter ATP-binding subunit; This model describes daunorubicin ... |
9-220 |
1.78e-37 |
|
daunorubicin resistance ABC transporter ATP-binding subunit; This model describes daunorubicin resistance ABC transporter, ATP binding subunit in bacteria and archaea. This model is restricted in its scope to preferentially recognize the ATP binding subunit associated with effux of the drug, daunorubicin. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. In eukaryotes proteins of similar function include p-gyco proteins, multidrug resistance protein etc. [Transport and binding proteins, Other]
Pssm-ID: 130256 [Multi-domain] Cd Length: 302 Bit Score: 132.90 E-value: 1.78e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 9 KWYGHFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQQGEITVDGIvvnDKKTDLAKLRSRVGMVFQHFEL 88
Cdd:TIGR01188 1 KVYGDFKAVDGVNFKVREGEVFGFLGPNGAGKTTTIRMLTTLLRPTSGTARVAGY---DVVREPRKVRRSIGIVPQYASV 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 89 FPHLSIIENLTL-AQVKVLKrnKAPAREKALKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMDPIAMLFDEPTSAL 167
Cdd:TIGR01188 78 DEDLTGRENLEMmGRLYGLP--KDEAEERAEELLELFELGEAADRPVGTYSGGMRRRLDIAASLIHQPDVLFLDEPTTGL 155
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 446554041 168 DPEMINEVLDVMVELANEGMTMMVVTHEMGFARKVANRVIFMDEGKII-EDSPK 220
Cdd:TIGR01188 156 DPRTRRAIWDYIRALKEEGVTILLTTHYMEEADKLCDRIAIIDHGRIIaEGTPE 209
|
|
| dppF |
PRK11308 |
dipeptide transporter ATP-binding subunit; Provisional |
34-228 |
2.67e-37 |
|
dipeptide transporter ATP-binding subunit; Provisional
Pssm-ID: 236898 [Multi-domain] Cd Length: 327 Bit Score: 133.17 E-value: 2.67e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEPVQQGEITVDGI-VVNDKKTDLAKLRSRVGMVFQHfelfPHLS---------IIE-----NL 98
Cdd:PRK11308 48 GESGCGKSTLARLLTMIETPTGGELYYQGQdLLKADPEAQKLLRQKIQIVFQN----PYGSlnprkkvgqILEeplliNT 123
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 99 TLaqvkvlkrNKAPAREKALKLLERVGLSA-HANKFPAQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLD 177
Cdd:PRK11308 124 SL--------SAAERREKALAMMAKVGLRPeHYDRYPHMFSGGQRQRIAIARALMLDPDVVVADEPVSALDVSVQAQVLN 195
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 446554041 178 VMVELANE-GMTMMVVTHEMGFARKVANRVIFMDEGKIIEDSPKDAFFDNPK 228
Cdd:PRK11308 196 LMMDLQQElGLSYVFISHDLSVVEHIADEVMVMYLGRCVEKGTKEQIFNNPR 247
|
|
| MglA |
COG1129 |
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; |
1-219 |
4.93e-37 |
|
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440745 [Multi-domain] Cd Length: 497 Bit Score: 135.53 E-value: 4.93e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 1 MITLKNVSKWYGHFQVLTDCStevkkgevvvvCGPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVnDKKTDLAKLRSRVG 80
Cdd:COG1129 4 LLEMRGISKSFGGVKALDGVSlelrpgevhalLGENGAGKSTLMKILSGVYQPDSGEILLDGEPV-RFRSPRDAQAAGIA 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 81 MVFQHFELFPHLSIIENLTLAQVK----VLKRNKapAREKALKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMDPI 156
Cdd:COG1129 83 IIHQELNLVPNLSVAENIFLGREPrrggLIDWRA--MRRRARELLARLGLDIDPDTPVGDLSVAQQQLVEIARALSRDAR 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446554041 157 AMLFDEPTSALDPEMINEVLDVMVELANEGMTMMVVTHEMGFARKVANRVIFMDEGKIIEDSP 219
Cdd:COG1129 161 VLILDEPTASLTEREVERLFRIIRRLKAQGVAIIYISHRLDEVFEIADRVTVLRDGRLVGTGP 223
|
|
| cbiO |
PRK13639 |
cobalt transporter ATP-binding subunit; Provisional |
34-241 |
5.56e-37 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184199 [Multi-domain] Cd Length: 275 Bit Score: 130.97 E-value: 5.56e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVNDKKTDLAKLRSRVGMVFQH--FELFPHlSIIE-------NLTLAQVK 104
Cdd:PRK13639 35 GPNGAGKSTLFLHFNGILKPTSGEVLIKGEPIKYDKKSLLEVRKTVGIVFQNpdDQLFAP-TVEEdvafgplNLGLSKEE 113
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 105 VLKRNKaparekalKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLDVMVELAN 184
Cdd:PRK13639 114 VEKRVK--------EALKAVGMEGFENKPPHHLSGGQKKRVAIAGILAMKPEIIVLDEPTSGLDPMGASQIMKLLYDLNK 185
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 446554041 185 EGMTMMVVTHEMGFARKVANRVIFMDEGKII-EDSPKDAFFDNPKSDRAKDFLAKILH 241
Cdd:PRK13639 186 EGITIIISTHDVDLVPVYADKVYVMSDGKIIkEGTPKEVFSDIETIRKANLRLPRVAH 243
|
|
| urea_trans_UrtE |
TIGR03410 |
urea ABC transporter, ATP-binding protein UrtE; Members of this protein family are ABC ... |
3-222 |
1.18e-36 |
|
urea ABC transporter, ATP-binding protein UrtE; Members of this protein family are ABC transporter ATP-binding subunits associated with urea transport and metabolism. This protein is found in a conserved five-gene transport operon typically found adjacent to urease genes. It was shown in Cyanobacteria that disruption leads to the loss of high-affinity urea transport activity. [Transport and binding proteins, Amino acids, peptides and amines]
Pssm-ID: 274567 [Multi-domain] Cd Length: 230 Bit Score: 128.80 E-value: 1.18e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 3 TLKNVSKWYGHFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQQGEITVDGivvndkkTDLAKL----RSR 78
Cdd:TIGR03410 2 EVSNLNVYYGQSHILRGVSLEVPKGEVTCVLGRNGVGKTTLLKTLMGLLPVKSGSIRLDG-------EDITKLppheRAR 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 79 VGM--VFQHFELFPHLSIIENLTLAqVKVLKRNKAPAREKALKLlervglsahankFPA----------QLSGGQQQRVA 146
Cdd:TIGR03410 75 AGIayVPQGREIFPRLTVEENLLTG-LAALPRRSRKIPDEIYEL------------FPVlkemlgrrggDLSGGQQQQLA 141
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446554041 147 IARALCMDPIAMLFDEPTSALDPEMINEVLDVMVELANE-GMTMMVVTHEMGFARKVANRVIFMDEGKIIEDSPKDA 222
Cdd:TIGR03410 142 IARALVTRPKLLLLDEPTEGIQPSIIKDIGRVIRRLRAEgGMAILLVEQYLDFARELADRYYVMERGRVVASGAGDE 218
|
|
| PRK10070 |
PRK10070 |
proline/glycine betaine ABC transporter ATP-binding protein ProV; |
34-236 |
1.46e-36 |
|
proline/glycine betaine ABC transporter ATP-binding protein ProV;
Pssm-ID: 182221 [Multi-domain] Cd Length: 400 Bit Score: 132.85 E-value: 1.46e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEPVQQGEITVDGIvvndkktDLAKL---------RSRVGMVFQHFELFPHLSIIEN----LTL 100
Cdd:PRK10070 61 GLSGSGKSTMVRLLNRLIEPTRGQVLIDGV-------DIAKIsdaelrevrRKKIAMVFQSFALMPHMTVLDNtafgMEL 133
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 101 AQVKVLKRnkapaREKALKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLDVMV 180
Cdd:PRK10070 134 AGINAEER-----REKALDALRQVGLENYAHSYPDELSGGMRQRVGLARALAINPDILLMDEAFSALDPLIRTEMQDELV 208
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 446554041 181 EL-ANEGMTMMVVTHEMGFARKVANRVIFMDEGKIIEDSPKDAFFDNPKSDRAKDFL 236
Cdd:PRK10070 209 KLqAKHQRTIVFISHDLDEAMRIGDRIAIMQNGEVVQVGTPDEILNNPANDYVRTFF 265
|
|
| ABC_DrrA |
cd03265 |
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein ... |
2-219 |
2.81e-36 |
|
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein component of a bacterial exporter complex that confers resistance to the antibiotics daunorubicin and doxorubicin. In addition to DrrA, the complex includes an integral membrane protein called DrrB. DrrA belongs to the ABC family of transporters and shares sequence and functional similarities with a protein found in cancer cells called P-glycoprotein. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213232 [Multi-domain] Cd Length: 220 Bit Score: 127.49 E-value: 2.81e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 2 ITLKNVSKWYGHFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQQGEITVDGIvvnDKKTDLAKLRSRVGM 81
Cdd:cd03265 1 IEVENLVKKYGDFEAVRGVSFRVRRGEIFGLLGPNGAGKTTTIKMLTTLLKPTSGRATVAGH---DVVREPREVRRRIGI 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 82 VFQHFELFPHLSIIENLTL-AQVKVLKRNKapAREKALKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMDPIAMLF 160
Cdd:cd03265 78 VFQDLSVDDELTGWENLYIhARLYGVPGAE--RRERIDELLDFVGLLEAADRLVKTYSGGMRRRLEIARSLVHRPEVLFL 155
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446554041 161 DEPTSALDPEMINEVLDVMVEL-ANEGMTMMVVTHEMGFARKVANRVIFMDEGKII-EDSP 219
Cdd:cd03265 156 DEPTIGLDPQTRAHVWEYIEKLkEEFGMTILLTTHYMEEAEQLCDRVAIIDHGRIIaEGTP 216
|
|
| PRK14246 |
PRK14246 |
phosphate ABC transporter ATP-binding protein; Provisional |
6-236 |
3.13e-36 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172734 [Multi-domain] Cd Length: 257 Bit Score: 128.63 E-value: 3.13e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 6 NVSKWYGHFQ---VLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVNDKK----TDLAKLRSR 78
Cdd:PRK14246 12 NISRLYLYINdkaILKDITIKIPNNSIFGIMGPSGSGKSTLLKVLNRLIEIYDSKIKVDGKVLYFGKdifqIDAIKLRKE 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 79 VGMVFQHFELFPHLSIIENLTLAQVKVLKRNKAPAREKALKLLERVGLSAHA----NKFPAQLSGGQQQRVAIARALCMD 154
Cdd:PRK14246 92 VGMVFQQPNPFPHLSIYDNIAYPLKSHGIKEKREIKKIVEECLRKVGLWKEVydrlNSPASQLSGGQQQRLTIARALALK 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 155 PIAMLFDEPTSALDPEMINEVLDVMVELANEgMTMMVVTHEMGFARKVANRVIFMDEGKIIEDSPKDAFFDNPKSDRAKD 234
Cdd:PRK14246 172 PKVLLMDEPTSMIDIVNSQAIEKLITELKNE-IAIVIVSHNPQQVARVADYVAFLYNGELVEWGSSNEIFTSPKNELTEK 250
|
..
gi 446554041 235 FL 236
Cdd:PRK14246 251 YV 252
|
|
| cbiO |
PRK13649 |
energy-coupling factor transporter ATPase; |
2-225 |
3.65e-36 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184208 [Multi-domain] Cd Length: 280 Bit Score: 129.09 E-value: 3.65e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 2 ITLKNVSKWYGH---FQ--VLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVN--DKKTDLAK 74
Cdd:PRK13649 3 INLQNVSYTYQAgtpFEgrALFDVNLTIEDGSYTAFIGHTGSGKSTIMQLLNGLHVPTQGSVRVDDTLITstSKNKDIKQ 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 75 LRSRVGMVFQhfelFPHLSIIENLTLAQVKVLKRNKAPAREKALKL----LERVGLSAHA-NKFPAQLSGGQQQRVAIAR 149
Cdd:PRK13649 83 IRKKVGLVFQ----FPESQLFEETVLKDVAFGPQNFGVSQEEAEALarekLALVGISESLfEKNPFELSGGQMRRVAIAG 158
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446554041 150 ALCMDPIAMLFDEPTSALDPEMINEVLDVMVELANEGMTMMVVTHEMGFARKVANRVIFMDEGKIIED-SPKDAFFD 225
Cdd:PRK13649 159 ILAMEPKILVLDEPTAGLDPKGRKELMTLFKKLHQSGMTIVLVTHLMDDVANYADFVYVLEKGKLVLSgKPKDIFQD 235
|
|
| cbiO |
PRK13635 |
energy-coupling factor ABC transporter ATP-binding protein; |
34-223 |
4.07e-36 |
|
energy-coupling factor ABC transporter ATP-binding protein;
Pssm-ID: 184195 [Multi-domain] Cd Length: 279 Bit Score: 128.98 E-value: 4.07e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVNDKktDLAKLRSRVGMVFQH---------------FELfphlsiiENL 98
Cdd:PRK13635 40 GHNGSGKSTLAKLLNGLLLPEAGTITVGGMVLSEE--TVWDVRRQVGMVFQNpdnqfvgatvqddvaFGL-------ENI 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 99 TLAQVKVLKRNKAParekalklLERVGLSAHANKFPAQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLDV 178
Cdd:PRK13635 111 GVPREEMVERVDQA--------LRQVGMEDFLNREPHRLSGGQKQRVAIAGVLALQPDIIILDEATSMLDPRGRREVLET 182
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 446554041 179 MVELANEGM-TMMVVTHEMGFARKvANRVIFMDEGKIIED-SPKDAF 223
Cdd:PRK13635 183 VRQLKEQKGiTVLSITHDLDEAAQ-ADRVIVMNKGEILEEgTPEEIF 228
|
|
| PRK10535 |
PRK10535 |
macrolide ABC transporter ATP-binding protein/permease MacB; |
1-219 |
4.32e-36 |
|
macrolide ABC transporter ATP-binding protein/permease MacB;
Pssm-ID: 182528 [Multi-domain] Cd Length: 648 Bit Score: 134.47 E-value: 4.32e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 1 MITLKNVSKWY----GHFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVNDKKTD-LAKL 75
Cdd:PRK10535 4 LLELKDIRRSYpsgeEQVEVLKGISLDIYAGEMVAIVGASGSGKSTLMNILGCLDKPTSGTYRVAGQDVATLDADaLAQL 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 76 R-SRVGMVFQHFELFPHLSIIENLTLAQVKVLKRNKApAREKALKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMD 154
Cdd:PRK10535 84 RrEHFGFIFQRYHLLSHLTAAQNVEVPAVYAGLERKQ-RLLRAQELLQRLGLEDRVEYQPSQLSGGQQQRVSIARALMNG 162
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446554041 155 PIAMLFDEPTSALDPEMINEVLDVMVELANEGMTMMVVTHEMGFARKvANRVIFMDEGKIIEDSP 219
Cdd:PRK10535 163 GQVILADEPTGALDSHSGEEVMAILHQLRDRGHTVIIVTHDPQVAAQ-AERVIEIRDGEIVRNPP 226
|
|
| type_I_sec_LssB |
TIGR03375 |
type I secretion system ATPase, LssB family; Type I protein secretion is a system in some ... |
34-222 |
4.65e-36 |
|
type I secretion system ATPase, LssB family; Type I protein secretion is a system in some Gram-negative bacteria to export proteins (often proteases) across both inner and outer membranes to the extracellular medium. This is one of three proteins of the type I secretion apparatus. Targeted proteins are not cleaved at the N-terminus, but rather carry signals located toward the extreme C-terminus to direct type I secretion. This model is related to models TIGR01842 and TIGR01846, and to bacteriocin ABC transporters that cleave their substrates during export. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis]
Pssm-ID: 274550 [Multi-domain] Cd Length: 694 Bit Score: 134.61 E-value: 4.65e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEPVQQGEITVDGivVNDKKTDLAKLRSRVGMVFQHFELFpHLSIIENLTLAqvkvlkrnkAPA 113
Cdd:TIGR03375 498 GRIGSGKSTLLKLLLGLYQPTEGSVLLDG--VDIRQIDPADLRRNIGYVPQDPRLF-YGTLRDNIALG---------APY 565
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 114 REKA--LKLLERVGLSAHANKFP-----------AQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLDVMV 180
Cdd:TIGR03375 566 ADDEeiLRAAELAGVTEFVRRHPdgldmqigergRSLSGGQRQAVALARALLRDPPILLLDEPTSAMDNRSEERFKDRLK 645
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 446554041 181 ELAnEGMTMMVVTHEMGFARKVaNRVIFMDEGKIIEDSPKDA 222
Cdd:TIGR03375 646 RWL-AGKTLVLVTHRTSLLDLV-DRIIVMDNGRIVADGPKDQ 685
|
|
| ABC_putative_ATPase |
cd03269 |
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the ... |
2-215 |
5.51e-36 |
|
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the subfamily A transporters involved in drug resistance, nodulation, lipid transport, and bacteriocin and lantibiotic immunity. In eubacteria and archaea, the typical organization consists of one ABC and one or two integral membranes. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213236 [Multi-domain] Cd Length: 210 Bit Score: 126.63 E-value: 5.51e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 2 ITLKNVSKWYGHFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQQGEITVDGivvndKKTDLAKlRSRVGM 81
Cdd:cd03269 1 LEVENVTKRFGRVTALDDISFSVEKGEIFGLLGPNGAGKTTTIRMILGIILPDSGEVLFDG-----KPLDIAA-RNRIGY 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 82 VFQHFELFPHLSIIENLT-LAQVKVLKrnKAPAREKALKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMDPIAMLF 160
Cdd:cd03269 75 LPEERGLYPKMKVIDQLVyLAQLKGLK--KEEARRRIDEWLERLELSEYANKRVEELSKGNQQKVQFIAAVIHDPELLIL 152
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 446554041 161 DEPTSALDPEMINEVLDVMVELANEGMTMMVVTHEMGFARKVANRVIFMDEGKII 215
Cdd:cd03269 153 DEPFSGLDPVNVELLKDVIRELARAGKTVILSTHQMELVEELCDRVLLLNKGRAV 207
|
|
| potG |
PRK11607 |
putrescine ABC transporter ATP-binding subunit PotG; |
1-239 |
7.23e-36 |
|
putrescine ABC transporter ATP-binding subunit PotG;
Pssm-ID: 183226 [Multi-domain] Cd Length: 377 Bit Score: 130.34 E-value: 7.23e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 1 MITLKNVSKWYGHFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQQGEITVDGIvvndkktDLAKL---RS 77
Cdd:PRK11607 19 LLEIRNLTKSFDGQHAVDDVSLTIYKGEIFALLGASGCGKSTLLRMLAGFEQPTAGQIMLDGV-------DLSHVppyQR 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 78 RVGMVFQHFELFPHLSIIENLTLAqvkvLKRNKAPAREKALKLLERVGLsAHANKF----PAQLSGGQQQRVAIARALCM 153
Cdd:PRK11607 92 PINMMFQSYALFPHMTVEQNIAFG----LKQDKLPKAEIASRVNEMLGL-VHMQEFakrkPHQLSGGQRQRVALARSLAK 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 154 DPIAMLFDEPTSALDPE----MINEVLDVmveLANEGMTMMVVTHEMGFARKVANRVIFMDEGKIIEDSPKDAFFDNPKS 229
Cdd:PRK11607 167 RPKLLLLDEPMGALDKKlrdrMQLEVVDI---LERVGVTCVMVTHDQEEAMTMAGRIAIMNRGKFVQIGEPEEIYEHPTT 243
|
250
....*....|
gi 446554041 230 DRAKDFLAKI 239
Cdd:PRK11607 244 RYSAEFIGSV 253
|
|
| NupO |
COG3845 |
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ... |
37-215 |
1.34e-35 |
|
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];
Pssm-ID: 443055 [Multi-domain] Cd Length: 504 Bit Score: 131.69 E-value: 1.34e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 37 GSGKSTLIKTVNGLEPVQQGEITVDGIVVNDKKTDLAkLRSRVGMVFQHFELFPHLSIIENLTLAQ--VKVLKRNKAPAR 114
Cdd:COG3845 41 GAGKSTLMKILYGLYQPDSGEILIDGKPVRIRSPRDA-IALGIGMVHQHFMLVPNLTVAENIVLGLepTKGGRLDRKAAR 119
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 115 EKALKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLDVMVELANEGMTMMVVTH 194
Cdd:COG3845 120 ARIRELSERYGLDVDPDAKVEDLSVGEQQRVEILKALYRGARILILDEPTAVLTPQEADELFEILRRLAAEGKSIIFITH 199
|
170 180
....*....|....*....|.
gi 446554041 195 EMGFARKVANRVIFMDEGKII 215
Cdd:COG3845 200 KLREVMAIADRVTVLRRGKVV 220
|
|
| PRK09984 |
PRK09984 |
phosphonate ABC transporter ATP-binding protein; |
1-230 |
1.81e-35 |
|
phosphonate ABC transporter ATP-binding protein;
Pssm-ID: 182182 [Multi-domain] Cd Length: 262 Bit Score: 126.67 E-value: 1.81e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 1 MITLKNVSKWYGHFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGL---EPVQQGEITVDGIVVNDK---KTDLAK 74
Cdd:PRK09984 4 IIRVEKLAKTFNQHQALHAVDLNIHHGEMVALLGPSGSGKSTLLRHLSGLitgDKSAGSHIELLGRTVQREgrlARDIRK 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 75 LRSRVGMVFQHFELFPHLSIIENLTLAQV------KVLKRNKAPA-REKALKLLERVGLSAHANKFPAQLSGGQQQRVAI 147
Cdd:PRK09984 84 SRANTGYIFQQFNLVNRLSVLENVLIGALgstpfwRTCFSWFTREqKQRALQALTRVGMVHFAHQRVSTLSGGQQQRVAI 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 148 ARALCMDPIAMLFDEPTSALDPEMINEVLDVMVEL-ANEGMTMMVVTHEMGFARKVANRVIFMDEGKIIEDSPKDAfFDN 226
Cdd:PRK09984 164 ARALMQQAKVILADEPIASLDPESARIVMDTLRDInQNDGITVVVTLHQVDYALRYCERIVALRQGHVFYDGSSQQ-FDN 242
|
....
gi 446554041 227 PKSD 230
Cdd:PRK09984 243 ERFD 246
|
|
| PRK13633 |
PRK13633 |
energy-coupling factor transporter ATPase; |
34-223 |
2.52e-35 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237453 [Multi-domain] Cd Length: 280 Bit Score: 126.74 E-value: 2.52e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVNDKKtDLAKLRSRVGMVFQHfelfPHLSII------------ENLTLA 101
Cdd:PRK13633 43 GRNGSGKSTIAKHMNALLIPSEGKVYVDGLDTSDEE-NLWDIRNKAGMVFQN----PDNQIVativeedvafgpENLGIP 117
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 102 QVKVlkrnkapaREKALKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLDVMVE 181
Cdd:PRK13633 118 PEEI--------RERVDESLKKVGMYEYRRHAPHLLSGGQKQRVAIAGILAMRPECIIFDEPTAMLDPSGRREVVNTIKE 189
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 446554041 182 L-ANEGMTMMVVTHEMGFARKvANRVIFMDEGKII-EDSPKDAF 223
Cdd:PRK13633 190 LnKKYGITIILITHYMEEAVE-ADRIIVMDSGKVVmEGTPKEIF 232
|
|
| SapF |
COG4167 |
ABC-type antimicrobial peptide export system, ATPase component SapF [Defense mechanisms]; |
34-230 |
5.32e-35 |
|
ABC-type antimicrobial peptide export system, ATPase component SapF [Defense mechanisms];
Pssm-ID: 443328 [Multi-domain] Cd Length: 265 Bit Score: 125.33 E-value: 5.32e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVNDKKTdlaKLRSR-VGMVFQHFE--LFPHLSIIENLTLAqvkvLKRN- 109
Cdd:COG4167 46 GENGSGKSTLAKMLAGIIEPTSGEILINGHKLEYGDY---KYRCKhIRMIFQDPNtsLNPRLNIGQILEEP----LRLNt 118
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 110 --KAPAREKALKL-LERVGLSA-HANKFPAQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLDVMVEL-AN 184
Cdd:COG4167 119 dlTAEEREERIFAtLRLVGLLPeHANFYPHMLSSGQKQRVALARALILQPKIIIADEALAALDMSVRSQIINLMLELqEK 198
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 446554041 185 EGMTMMVVTHEMGFARKVANRVIFMDEGKIIEDSPKDAFFDNPKSD 230
Cdd:COG4167 199 LGISYIYVSQHLGIVKHISDKVLVMHQGEVVEYGKTAEVFANPQHE 244
|
|
| PRK11000 |
PRK11000 |
maltose/maltodextrin ABC transporter ATP-binding protein MalK; |
2-214 |
8.61e-35 |
|
maltose/maltodextrin ABC transporter ATP-binding protein MalK;
Pssm-ID: 182893 [Multi-domain] Cd Length: 369 Bit Score: 127.45 E-value: 8.61e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 2 ITLKNVSKWYGHFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVNDKKTdlAKlRSrVGM 81
Cdd:PRK11000 4 VTLRNVTKAYGDVVISKDINLDIHEGEFVVFVGPSGCGKSTLLRMIAGLEDITSGDLFIGEKRMNDVPP--AE-RG-VGM 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 82 VFQHFELFPHLSIIENLTLAqVKVLKRNKAPAREKALKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMDPIAMLFD 161
Cdd:PRK11000 80 VFQSYALYPHLSVAENMSFG-LKLAGAKKEEINQRVNQVAEVLQLAHLLDRKPKALSGGQRQRVAIGRTLVAEPSVFLLD 158
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 446554041 162 EPTSALDP----EMINEVLDVMVELaneGMTMMVVTHEMGFARKVANRVIFMDEGKI 214
Cdd:PRK11000 159 EPLSNLDAalrvQMRIEISRLHKRL---GRTMIYVTHDQVEAMTLADKIVVLDAGRV 212
|
|
| ABC_NatA_sodium_exporter |
cd03266 |
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a ... |
1-217 |
1.11e-34 |
|
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of a single ATP-binding protein and a single integral membrane protein.
Pssm-ID: 213233 [Multi-domain] Cd Length: 218 Bit Score: 123.25 E-value: 1.11e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 1 MITLKNVSKWY----GHFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVNdkkTDLAKLR 76
Cdd:cd03266 1 MITADALTKRFrdvkKTVQAVDGVSFTVKPGEVTGLLGPNGAGKTTTLRMLAGLLEPDAGFATVDGFDVV---KEPAEAR 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 77 SRVGMVFQHFELFPHLSIIENLT-LAQVKVLKRNKAPAREKalKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMDP 155
Cdd:cd03266 78 RRLGFVSDSTGLYDRLTARENLEyFAGLYGLKGDELTARLE--ELADRLGMEELLDRRVGGFSTGMRQKVAIARALVHDP 155
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446554041 156 IAMLFDEPTSALDPEMINEVLDVMVELANEGMTMMVVTHEMGFARKVANRVIFMDEGKIIED 217
Cdd:cd03266 156 PVLLLDEPTTGLDVMATRALREFIRQLRALGKCILFSTHIMQEVERLCDRVVVLHRGRVVYE 217
|
|
| cbiO |
PRK13646 |
energy-coupling factor transporter ATPase; |
2-228 |
1.81e-34 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184205 [Multi-domain] Cd Length: 286 Bit Score: 124.89 E-value: 1.81e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 2 ITLKNVSKWYG-----HFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVNDKKTD--LAK 74
Cdd:PRK13646 3 IRFDNVSYTYQkgtpyEHQAIHDVNTEFEQGKYYAIVGQTGSGKSTLIQNINALLKPTTGTVTVDDITITHKTKDkyIRP 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 75 LRSRVGMVFQhfelFPHLSIIENLTLAQV----KVLKRNKAPAREKALKLLERVGLSAHA-NKFPAQLSGGQQQRVAIAR 149
Cdd:PRK13646 83 VRKRIGMVFQ----FPESQLFEDTVEREIifgpKNFKMNLDEVKNYAHRLLMDLGFSRDVmSQSPFQMSGGQMRKIAIVS 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 150 ALCMDPIAMLFDEPTSALDPEMINEVLDVMVELA-NEGMTMMVVTHEMGFARKVANRVIFMDEGKIIED-SPKDAFFDNP 227
Cdd:PRK13646 159 ILAMNPDIIVLDEPTAGLDPQSKRQVMRLLKSLQtDENKTIILVSHDMNEVARYADEVIVMKEGSIVSQtSPKELFKDKK 238
|
.
gi 446554041 228 K 228
Cdd:PRK13646 239 K 239
|
|
| nikE |
PRK10419 |
nickel ABC transporter ATP-binding protein NikE; |
1-219 |
2.66e-34 |
|
nickel ABC transporter ATP-binding protein NikE;
Pssm-ID: 236689 [Multi-domain] Cd Length: 268 Bit Score: 123.64 E-value: 2.66e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 1 MITLKNVSKWYGHF---------QVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQQGEITVDGivvndkkTD 71
Cdd:PRK10419 3 LLNVSGLSHHYAHGglsgkhqhqTVLNNVSLSLKSGETVALLGRSGCGKSTLARLLVGLESPSQGNVSWRG-------EP 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 72 LAKL--------RSRVGMVFQHF--ELFPHLSIIENLTLAQVKVLKRNKAPAREKALKLLERVGLSA-HANKFPAQLSGG 140
Cdd:PRK10419 76 LAKLnraqrkafRRDIQMVFQDSisAVNPRKTVREIIREPLRHLLSLDKAERLARASEMLRAVDLDDsVLDKRPPQLSGG 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 141 QQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLDVMVELANE-GMTMMVVTHEMGFARKVANRVIFMDEGKIIEDSP 219
Cdd:PRK10419 156 QLQRVCLARALAVEPKLLILDEAVSNLDLVLQAGVIRLLKKLQQQfGTACLFITHDLRLVERFCQRVMVMDNGQIVETQP 235
|
|
| ugpC |
PRK11650 |
sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC; |
1-214 |
4.79e-34 |
|
sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;
Pssm-ID: 236947 [Multi-domain] Cd Length: 356 Bit Score: 125.34 E-value: 4.79e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 1 MITLKNVSKWY-GHFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVND---KKTDLAklr 76
Cdd:PRK11650 3 GLKLQAVRKSYdGKTQVIKGIDLDVADGEFIVLVGPSGCGKSTLLRMVAGLERITSGEIWIGGRVVNElepADRDIA--- 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 77 srvgMVFQHFELFPHLSIIENLTLAqvkvLKRNKAP-----AR-EKALKLLErvgLSAHANKFPAQLSGGQQQRVAIARA 150
Cdd:PRK11650 80 ----MVFQNYALYPHMSVRENMAYG----LKIRGMPkaeieERvAEAARILE---LEPLLDRKPRELSGGQRQRVAMGRA 148
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446554041 151 LCMDPIAMLFDEPTSALDP----EMINEVLDVMVELaneGMTMMVVTHEMGFARKVANRVIFMDEGKI 214
Cdd:PRK11650 149 IVREPAVFLFDEPLSNLDAklrvQMRLEIQRLHRRL---KTTSLYVTHDQVEAMTLADRVVVMNGGVA 213
|
|
| PRK14243 |
PRK14243 |
phosphate transporter ATP-binding protein; Provisional |
5-237 |
5.96e-34 |
|
phosphate transporter ATP-binding protein; Provisional
Pssm-ID: 184588 [Multi-domain] Cd Length: 264 Bit Score: 122.97 E-value: 5.96e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 5 KNVSKWYGHFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPV-----QQGEITVDGIVVNDKKTDLAKLRSRV 79
Cdd:PRK14243 14 ENLNVYYGSFLAVKNVWLDIPKNQITAFIGPSGCGKSTILRCFNRLNDLipgfrVEGKVTFHGKNLYAPDVDPVEVRRRI 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 80 GMVFQHFELFPHlSIIENLTL-AQVKVLKRNKAPAREKALKL----------LERVGLSahankfpaqLSGGQQQRVAIA 148
Cdd:PRK14243 94 GMVFQKPNPFPK-SIYDNIAYgARINGYKGDMDELVERSLRQaalwdevkdkLKQSGLS---------LSGGQQQRLCIA 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 149 RALCMDPIAMLFDEPTSALDPEMINEVLDVMVELAnEGMTMMVVTHEMGFARKVANRVIFMD---------EGKIIEDSP 219
Cdd:PRK14243 164 RAIAVQPEVILMDEPCSALDPISTLRIEELMHELK-EQYTIIIVTHNMQQAARVSDMTAFFNveltegggrYGYLVEFDR 242
|
250
....*....|....*...
gi 446554041 220 KDAFFDNPKSDRAKDFLA 237
Cdd:PRK14243 243 TEKIFNSPQQQATRDYVS 260
|
|
| PRK10584 |
PRK10584 |
putative ABC transporter ATP-binding protein YbbA; Provisional |
34-218 |
7.86e-34 |
|
putative ABC transporter ATP-binding protein YbbA; Provisional
Pssm-ID: 182569 [Multi-domain] Cd Length: 228 Bit Score: 121.42 E-value: 7.86e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVND-KKTDLAKLRSR-VGMVFQHFELFPHLSIIENLtlaQVKVLKR--N 109
Cdd:PRK10584 43 GESGSGKSTLLAILAGLDDGSSGEVSLVGQPLHQmDEEARAKLRAKhVGFVFQSFMLIPTLNALENV---ELPALLRgeS 119
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 110 KAPAREKALKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLDVMVELANE-GMT 188
Cdd:PRK10584 120 SRQSRNGAKALLEQLGLGKRLDHLPAQLSGGEQQRVALARAFNGRPDVLFADEPTGNLDRQTGDKIADLLFSLNREhGTT 199
|
170 180 190
....*....|....*....|....*....|
gi 446554041 189 MMVVTHEMGFARKVANRVIFMDeGKIIEDS 218
Cdd:PRK10584 200 LILVTHDLQLAARCDRRLRLVN-GQLQEEA 228
|
|
| ABCC_Hemolysin |
cd03252 |
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a ... |
2-225 |
1.93e-33 |
|
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a central component of the secretion machinery that translocates the toxin, hemolysin A, in a Sec-independent fashion across both membranes of E. coli. The hemolysin A (HlyA) transport machinery is composed of the ATP-binding cassette (ABC) transporter HlyB located in the inner membrane, hemolysin D (HlyD), also anchored in the inner membrane, and TolC, which resides in the outer membrane. HlyD apparently forms a continuous channel that bridges the entire periplasm, interacting with TolC and HlyB. This arrangement prevents the appearance of periplasmic intermediates of HlyA during substrate transport. Little is known about the molecular details of HlyA transport, but it is evident that ATP-hydrolysis by the ABC-transporter HlyB is a necessary source of energy.
Pssm-ID: 213219 [Multi-domain] Cd Length: 237 Bit Score: 120.67 E-value: 1.93e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 2 ITLKNVSKWYG--HFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQQGEITVDGivvNDKKT-DLAKLRSR 78
Cdd:cd03252 1 ITFEHVRFRYKpdGPVILDNISLRIKPGEVVGIVGRSGSGKSTLTKLIQRFYVPENGRVLVDG---HDLALaDPAWLRRQ 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 79 VGMVFQHFELFpHLSIIENLTLAqvkvlkrNKAPAREKALKLLERVGLSAHANKFP-----------AQLSGGQQQRVAI 147
Cdd:cd03252 78 VGVVLQENVLF-NRSIRDNIALA-------DPGMSMERVIEAAKLAGAHDFISELPegydtivgeqgAGLSGGQRQRIAI 149
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446554041 148 ARALCMDPIAMLFDEPTSALDPEMINEVLDVMVELAnEGMTMMVVTHEMGFARKvANRVIFMDEGKIIEDSPKDAFFD 225
Cdd:cd03252 150 ARALIHNPRILIFDEATSALDYESEHAIMRNMHDIC-AGRTVIIIAHRLSTVKN-ADRIIVMEKGRIVEQGSHDELLA 225
|
|
| lolD |
PRK11629 |
lipoprotein-releasing ABC transporter ATP-binding protein LolD; |
6-214 |
2.13e-33 |
|
lipoprotein-releasing ABC transporter ATP-binding protein LolD;
Pssm-ID: 183244 [Multi-domain] Cd Length: 233 Bit Score: 120.69 E-value: 2.13e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 6 NVSKWYGHFQVLTDC----STEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVND-KKTDLAKLRSR-V 79
Cdd:PRK11629 10 NLCKRYQEGSVQTDVlhnvSFSIGEGEMMAIVGSSGSGKSTLLHLLGGLDTPTSGDVIFNGQPMSKlSSAAKAELRNQkL 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 80 GMVFQHFELFPHLSIIENLTLAQVkVLKRNKAPAREKALKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMDPIAML 159
Cdd:PRK11629 90 GFIYQFHHLLPDFTALENVAMPLL-IGKKKPAEINSRALEMLAAVGLEHRANHRPSELSGGERQRVAIARALVNNPRLVL 168
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 446554041 160 FDEPTSALDPEMINEVLDVMVEL-ANEGMTMMVVTHEMGFARKVaNRVIFMDEGKI 214
Cdd:PRK11629 169 ADEPTGNLDARNADSIFQLLGELnRLQGTAFLVVTHDLQLAKRM-SRQLEMRDGRL 223
|
|
| cbiO |
PRK13647 |
cobalt transporter ATP-binding subunit; Provisional |
34-215 |
2.19e-33 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237457 [Multi-domain] Cd Length: 274 Bit Score: 121.38 E-value: 2.19e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVNDKktDLAKLRSRVGMVFQH--FELFPhLSIIE-------NLTLAQVK 104
Cdd:PRK13647 38 GPNGAGKSTLLLHLNGIYLPQRGRVKVMGREVNAE--NEKWVRSKVGLVFQDpdDQVFS-STVWDdvafgpvNMGLDKDE 114
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 105 VLKRNkaparEKALKLlerVGLSAHANKFPAQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLDVMVELAN 184
Cdd:PRK13647 115 VERRV-----EEALKA---VRMWDFRDKPPYHLSYGQKKRVAIAGVLAMDPDVIVLDEPMAYLDPRGQETLMEILDRLHN 186
|
170 180 190
....*....|....*....|....*....|.
gi 446554041 185 EGMTMMVVTHEMGFARKVANRVIFMDEGKII 215
Cdd:PRK13647 187 QGKTVIVATHDVDLAAEWADQVIVLKEGRVL 217
|
|
| tauB |
PRK11248 |
taurine ABC transporter ATP-binding subunit; |
1-216 |
2.43e-33 |
|
taurine ABC transporter ATP-binding subunit;
Pssm-ID: 183056 [Multi-domain] Cd Length: 255 Bit Score: 120.96 E-value: 2.43e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 1 MITLKNVSKWYGHFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVNDKKTDLaklrsrvG 80
Cdd:PRK11248 1 MLQISHLYADYGGKPALEDINLTLESGELLVVLGPSGCGKTTLLNLIAGFVPYQHGSITLDGKPVEGPGAER-------G 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 81 MVFQHFELFPHLSIIEN----LTLAQVKVLKRnkapaREKALKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMDPI 156
Cdd:PRK11248 74 VVFQNEGLLPWRNVQDNvafgLQLAGVEKMQR-----LEIAHQMLKKVGLEGAEKRYIWQLSGGQRQRVGIARALAANPQ 148
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446554041 157 AMLFDEPTSALDPEMINEVLDVMVELANE-GMTMMVVTHEMGFARKVANRVIFM--DEGKIIE 216
Cdd:PRK11248 149 LLLLDEPFGALDAFTREQMQTLLLKLWQEtGKQVLLITHDIEEAVFMATELVLLspGPGRVVE 211
|
|
| modC |
PRK11144 |
molybdenum ABC transporter ATP-binding protein ModC; |
34-215 |
3.15e-33 |
|
molybdenum ABC transporter ATP-binding protein ModC;
Pssm-ID: 182993 [Multi-domain] Cd Length: 352 Bit Score: 123.06 E-value: 3.15e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVND--KKTDLAKLRSRVGMVFQHFELFPHLSIIENLTLAqvkvLKRNKA 111
Cdd:PRK11144 31 GRSGAGKTSLINAISGLTRPQKGRIVLNGRVLFDaeKGICLPPEKRRIGYVFQDARLFPHYKVRGNLRYG----MAKSMV 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 112 PAREKALKLLervGLSAHANKFPAQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLDVMVELANEGMTMMV 191
Cdd:PRK11144 107 AQFDKIVALL---GIEPLLDRYPGSLSGGEKQRVAIGRALLTAPELLLMDEPLASLDLPRKRELLPYLERLAREINIPIL 183
|
170 180
....*....|....*....|....*
gi 446554041 192 -VTHEMGFARKVANRVIFMDEGKII 215
Cdd:PRK11144 184 yVSHSLDEILRLADRVVVLEQGKVK 208
|
|
| ModF |
COG1119 |
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA ... |
34-227 |
5.12e-33 |
|
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA [Inorganic ion transport and metabolism];
Pssm-ID: 440736 [Multi-domain] Cd Length: 250 Bit Score: 119.80 E-value: 5.12e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLE-PVQQGEITVDGivvNDK-KTDLAKLRSRVGMVFQHFelfpHLSIIENLTLAQVkVL----- 106
Cdd:COG1119 36 GPNGAGKSTLLSLITGDLpPTYGNDVRLFG---ERRgGEDVWELRKRIGLVSPAL----QLRFPRDETVLDV-VLsgffd 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 107 -----KRNKAPAREKALKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLDVMVE 181
Cdd:COG1119 108 siglyREPTDEQRERARELLELLGLAHLADRPFGTLSQGEQRRVLIARALVKDPELLILDEPTAGLDLGARELLLALLDK 187
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446554041 182 LANEGMTMMV-VTH---EM--GFarkvaNRVIFMDEGKIIEDSPKD---------AFFDNP 227
Cdd:COG1119 188 LAAEGAPTLVlVTHhveEIppGI-----THVLLLKDGRVVAAGPKEevltsenlsEAFGLP 243
|
|
| YhaQ |
COG4152 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
1-221 |
6.40e-33 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 443322 [Multi-domain] Cd Length: 298 Bit Score: 120.98 E-value: 6.40e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 1 MITLKNVSKWYGHFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVNDKKtdlaklRSRVG 80
Cdd:COG4152 1 MLELKGLTKRFGDKTAVDDVSFTVPKGEIFGLLGPNGAGKTTTIRIILGILAPDSGEVLWDGEPLDPED------RRRIG 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 81 -MVfqhfE---LFPHLSIIENLT-LAQVKVLKRNKapAREKALKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMDP 155
Cdd:COG4152 75 yLP----EergLYPKMKVGEQLVyLARLKGLSKAE--AKRRADEWLERLGLGDRANKKVEELSKGNQQKVQLIAALLHDP 148
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446554041 156 IAMLFDEPTSALDPEMINEVLDVMVELANEGMTMMVVTHEMGFARKVANRVIFMDEGKIIEDSPKD 221
Cdd:COG4152 149 ELLILDEPFSGLDPVNVELLKDVIRELAAKGTTVIFSSHQMELVEELCDRIVIINKGRKVLSGSVD 214
|
|
| ABCC_bacteriocin_exporters |
cd03245 |
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic ... |
34-217 |
9.89e-33 |
|
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic bacteriocins of lactic acid bacteria are produced as precursors which have N-terminal leader peptides that share similarities in amino acid sequence and contain a conserved processing site of two glycine residues in positions -1 and -2. A dedicated ATP-binding cassette (ABC) transporter is responsible for the proteolytic cleavage of the leader peptides and subsequent translocation of the bacteriocins across the cytoplasmic membrane.
Pssm-ID: 213212 [Multi-domain] Cd Length: 220 Bit Score: 118.46 E-value: 9.89e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEPVQQGEITVDGIvvNDKKTDLAKLRSRVGMVFQHFELFpHLSIIENLTLAqvkvlkrnkAPA 113
Cdd:cd03245 37 GRVGSGKSTLLKLLAGLYKPTSGSVLLDGT--DIRQLDPADLRRNIGYVPQDVTLF-YGTLRDNITLG---------APL 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 114 --REKALKLLERVGLSAHANKFP-----------AQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLDVMV 180
Cdd:cd03245 105 adDERILRAAELAGVTDFVNKHPngldlqigergRGLSGGQRQAVALARALLNDPPILLLDEPTSAMDMNSEERLKERLR 184
|
170 180 190
....*....|....*....|....*....|....*..
gi 446554041 181 ELAnEGMTMMVVTHEMGFArKVANRVIFMDEGKIIED 217
Cdd:cd03245 185 QLL-GDKTLIIITHRPSLL-DLVDRIIVMDSGRIVAD 219
|
|
| ABC_Carb_Monos_I |
cd03216 |
First domain of the ATP-binding cassette component of monosaccharide transport system; This ... |
2-215 |
1.38e-32 |
|
First domain of the ATP-binding cassette component of monosaccharide transport system; This family represents the domain I of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. Pentoses include xylose, arabinose, and ribose. Important hexoses include glucose, galactose, and fructose. In members of the Carb_monos family, the single hydrophobic gene product forms a homodimer while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.
Pssm-ID: 213183 [Multi-domain] Cd Length: 163 Bit Score: 116.37 E-value: 1.38e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 2 ITLKNVSKWYGHFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVNdKKTDLAKLRSRVGM 81
Cdd:cd03216 1 LELRGITKRFGGVKALDGVSLSVRRGEVHALLGENGAGKSTLMKILSGLYKPDSGEILVDGKEVS-FASPRDARRAGIAM 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 82 VFQhfelfphlsiienltlaqvkvlkrnkaparekalkllervglsahankfpaqLSGGQQQRVAIARALCMDPIAMLFD 161
Cdd:cd03216 80 VYQ----------------------------------------------------LSVGERQMVEIARALARNARLLILD 107
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 446554041 162 EPTSALDPEMINEVLDVMVELANEGMTMMVVTHEMGFARKVANRVIFMDEGKII 215
Cdd:cd03216 108 EPTAALTPAEVERLFKVIRRLRAQGVAVIFISHRLDEVFEIADRVTVLRDGRVV 161
|
|
| PRK10908 |
PRK10908 |
cell division ATP-binding protein FtsE; |
1-214 |
2.53e-32 |
|
cell division ATP-binding protein FtsE;
Pssm-ID: 182829 [Multi-domain] Cd Length: 222 Bit Score: 117.28 E-value: 2.53e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 1 MITLKNVSKWY-GHFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVND-KKTDLAKLRSR 78
Cdd:PRK10908 1 MIRFEHVSKAYlGGRQALQGVTFHMRPGEMAFLTGHSGAGKSTLLKLICGIERPSAGKIWFSGHDITRlKNREVPFLRRQ 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 79 VGMVFQHFELFPHLSIIENLTLAQVkVLKRNKAPAREKALKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMDPIAM 158
Cdd:PRK10908 81 IGMIFQDHHLLMDRTVYDNVAIPLI-IAGASGDDIRRRVSAALDKVGLLDKAKNFPIQLSGGEQQRVGIARAVVNKPAVL 159
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 446554041 159 LFDEPTSALDPEMINEVLDVMVELANEGMTMMVVTHEMGFARKVANRVIFMDEGKI 214
Cdd:PRK10908 160 LADEPTGNLDDALSEGILRLFEEFNRVGVTVLMATHDIGLISRRSYRMLTLSDGHL 215
|
|
| cbiO |
PRK13643 |
energy-coupling factor transporter ATPase; |
34-223 |
2.71e-32 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184203 [Multi-domain] Cd Length: 288 Bit Score: 119.07 E-value: 2.71e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVND--KKTDLAKLRSRVGMVFQhfelFPHLSIIENLTLAQVKVLKRNKA 111
Cdd:PRK13643 39 GHTGSGKSTLLQHLNGLLQPTEGKVTVGDIVVSStsKQKEIKPVRKKVGVVFQ----FPESQLFEETVLKDVAFGPQNFG 114
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 112 PAREKALKL----LERVGLSAHA-NKFPAQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLDVMVELANEG 186
Cdd:PRK13643 115 IPKEKAEKIaaekLEMVGLADEFwEKSPFELSGGQMRRVAIAGILAMEPEVLVLDEPTAGLDPKARIEMMQLFESIHQSG 194
|
170 180 190
....*....|....*....|....*....|....*...
gi 446554041 187 MTMMVVTHEMGFARKVANRVIFMDEGKIIE-DSPKDAF 223
Cdd:PRK13643 195 QTVVLVTHLMDDVADYADYVYLLEKGHIIScGTPSDVF 232
|
|
| cbiO |
PRK13636 |
cobalt transporter ATP-binding subunit; Provisional |
34-241 |
3.70e-32 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184196 [Multi-domain] Cd Length: 283 Bit Score: 118.41 E-value: 3.70e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVNDKKTDLAKLRSRVGMVFQH--FELFPhLSIIENLTLAQVKvLKRNKA 111
Cdd:PRK13636 39 GGNGAGKSTLFQNLNGILKPSSGRILFDGKPIDYSRKGLMKLRESVGMVFQDpdNQLFS-ASVYQDVSFGAVN-LKLPED 116
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 112 PAREKALKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLDVMVELANE-GMTMM 190
Cdd:PRK13636 117 EVRKRVDNALKRTGIEHLKDKPTHCLSFGQKKRVAIAGVLVMEPKVLVLDEPTAGLDPMGVSEIMKLLVEMQKElGLTII 196
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 446554041 191 VVTHEMGFARKVANRVIFMDEGKII-EDSPKDAFFDNPKSDRAKDFLAKILH 241
Cdd:PRK13636 197 IATHDIDIVPLYCDNVFVMKEGRVIlQGNPKEVFAEKEMLRKVNLRLPRIGH 248
|
|
| cbiO |
PRK13645 |
energy-coupling factor transporter ATPase; |
2-239 |
4.01e-32 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184204 [Multi-domain] Cd Length: 289 Bit Score: 118.57 E-value: 4.01e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 2 ITLKNVSKWYG-----HFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQQGEITVD--GIVVNDKK-TDLA 73
Cdd:PRK13645 7 IILDNVSYTYAkktpfEFKALNNTSLTFKKNKVTCVIGTTGSGKSTMIQLTNGLIISETGQTIVGdyAIPANLKKiKEVK 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 74 KLRSRVGMVFQ--HFELFPHlSIIENLTLAQVKvLKRNKAPAREKALKLLERVGL-SAHANKFPAQLSGGQQQRVAIARA 150
Cdd:PRK13645 87 RLRKEIGLVFQfpEYQLFQE-TIEKDIAFGPVN-LGENKQEAYKKVPELLKLVQLpEDYVKRSPFELSGGQKRRVALAGI 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 151 LCMDPIAMLFDEPTSALDPEMINEVLDVMVEL-ANEGMTMMVVTHEMGFARKVANRVIFMDEGKIIEDSPKDAFFDNpks 229
Cdd:PRK13645 165 IAMDGNTLVLDEPTGGLDPKGEEDFINLFERLnKEYKKRIIMVTHNMDQVLRIADEVIVMHEGKVISIGSPFEIFSN--- 241
|
250
....*....|
gi 446554041 230 draKDFLAKI 239
Cdd:PRK13645 242 ---QELLTKI 248
|
|
| ABCC_Glucan_exporter_like |
cd03254 |
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan ... |
2-216 |
6.79e-32 |
|
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan exporter ATP-binding protein. In A. tumefaciens cyclic beta-1, 2-glucan must be transported into the periplasmic space to exert its action as a virulence factor. This subfamily belongs to the MRP-like family and is involved in drug, peptide, and lipid export. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains each composed of six transmembrane (TM) helices and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213221 [Multi-domain] Cd Length: 229 Bit Score: 116.56 E-value: 6.79e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 2 ITLKNVSKWYGH-FQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQQGEITVDGIvvNDKKTDLAKLRSRVG 80
Cdd:cd03254 3 IEFENVNFSYDEkKPVLKDINFSIKPGETVAIVGPTGAGKTTLINLLMRFYDPQKGQILIDGI--DIRDISRKSLRSMIG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 81 MVFQHFELFPHlSIIENLTL----AQVKVLkrNKAPAREKALKLLERV--GLSAHANKFPAQLSGGQQQRVAIARALCMD 154
Cdd:cd03254 81 VVLQDTFLFSG-TIMENIRLgrpnATDEEV--IEAAKEAGAHDFIMKLpnGYDTVLGENGGNLSQGERQLLAIARAMLRD 157
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446554041 155 PIAMLFDEPTSALDPEMINEVLDVMVELaNEGMTMMVVTHEMGFARKvANRVIFMDEGKIIE 216
Cdd:cd03254 158 PKILILDEATSNIDTETEKLIQEALEKL-MKGRTSIIIAHRLSTIKN-ADKILVLDDGKIIE 217
|
|
| ntrCD |
TIGR01184 |
nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits ... |
34-212 |
9.31e-32 |
|
nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits of nitrate transport in bacteria and archaea. This protein belongs to the ATP-binding cassette (ABC) superfamily. It is thought that the two subunits encoded by ntrC and ntrD form the binding surface for interaction with ATP. This model is restricted in identifying ATP binding subunit associated with the nitrate transport. Nitrate assimilation is aided by other proteins derived from the operon which among others include products of ntrA - a regulatory protein; ntrB - a hydropbobic transmembrane permease and narB - a reductase. [Transport and binding proteins, Anions, Transport and binding proteins, Other]
Pssm-ID: 130252 [Multi-domain] Cd Length: 230 Bit Score: 116.03 E-value: 9.31e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVNDKKTDlaklrsRVgMVFQHFELFPHLSIIENLTLAQVKVLKRNKAPA 113
Cdd:TIGR01184 18 GHSGCGKSTLLNLISGLAQPTSGGVILEGKQITEPGPD------RM-VVFQNYSLLPWLTVRENIALAVDRVLPDLSKSE 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 114 REKALK-LLERVGLSAHANKFPAQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLDVMVELANE-GMTMMV 191
Cdd:TIGR01184 91 RRAIVEeHIALVGLTEAADKRPGQLSGGMKQRVAIARALSIRPKVLLLDEPFGALDALTRGNLQEELMQIWEEhRVTVLM 170
|
170 180
....*....|....*....|.
gi 446554041 192 VTHEMGFARKVANRVIFMDEG 212
Cdd:TIGR01184 171 VTHDVDEALLLSDRVVMLTNG 191
|
|
| cbiO |
TIGR01166 |
cobalt transport protein ATP-binding subunit; This model describes the ATP binding subunit of ... |
34-199 |
1.20e-31 |
|
cobalt transport protein ATP-binding subunit; This model describes the ATP binding subunit of the multisubunit cobalt transporter in bacteria and its equivalents in archaea. The model is restricted to ATP subunit that is a part of the cobalt transporter, which belongs to the ABC transporter superfamily (ATP Binding Cassette). The model excludes ATP binding subunit that are associated with other transporters belonging to ABC transporter superfamily. This superfamily includes two groups, one which catalyze the uptake of small molecules, including ions from the external milieu and the other group which is engaged in the efflux of small molecular weight compounds and ions from within the cell. Energy derived from the hydrolysis of ATP drive the both the process of uptake and efflux. [Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 130234 [Multi-domain] Cd Length: 190 Bit Score: 114.83 E-value: 1.20e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVNDKKTDLAKLRSRVGMVFQHFE--LFpHLSIIENLTLAQVKvLKRNKA 111
Cdd:TIGR01166 25 GANGAGKSTLLLHLNGLLRPQSGAVLIDGEPLDYSRKGLLERRQRVGLVFQDPDdqLF-AADVDQDVAFGPLN-LGLSEA 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 112 PAREKALKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLDVMVELANEGMTMMV 191
Cdd:TIGR01166 103 EVERRVREALTAVGASGLRERPTHCLSGGEKKRVAIAGAVAMRPDVLLLDEPTAGLDPAGREQMLAILRRLRAEGMTVVI 182
|
....*...
gi 446554041 192 VTHEMGFA 199
Cdd:TIGR01166 183 STHDVDLA 190
|
|
| ABCC_MsbA |
cd03251 |
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; ... |
34-217 |
1.42e-31 |
|
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; MsbA is an essential ABC transporter, closely related to eukaryotic MDR proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213218 [Multi-domain] Cd Length: 234 Bit Score: 115.79 E-value: 1.42e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVNDKKtdLAKLRSRVGMVFQHFELFpHLSIIENLTLAqvkvlKRNKAPA 113
Cdd:cd03251 35 GPSGSGKSTLVNLIPRFYDVDSGRILIDGHDVRDYT--LASLRRQIGLVSQDVFLF-NDTVAENIAYG-----RPGATRE 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 114 R-EKALKLlervglsAHANKF----P-----------AQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLD 177
Cdd:cd03251 107 EvEEAARA-------ANAHEFimelPegydtvigergVKLSGGQRQRIAIARALLKDPPILILDEATSALDTESERLVQA 179
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 446554041 178 VMVELAnEGMTMMVVTHEMGFARKvANRVIFMDEGKIIED 217
Cdd:cd03251 180 ALERLM-KNRTTFVIAHRLSTIEN-ADRIVVLEDGKIVER 217
|
|
| COG4559 |
COG4559 |
ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism]; |
1-223 |
2.58e-31 |
|
ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443620 [Multi-domain] Cd Length: 258 Bit Score: 115.60 E-value: 2.58e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 1 MITLKNVSKWYGHFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNG-LEPvQQGEITVDGIVVND-KKTDLAKLRsr 78
Cdd:COG4559 1 MLEAENLSVRLGGRTLLDDVSLTLRPGELTAIIGPNGAGKSTLLKLLTGeLTP-SSGEVRLNGRPLAAwSPWELARRR-- 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 79 vGMVFQHFEL-FPhlsiienLTLAQVKVLKR-----NKAPAREKALKLLERVGLSAHANKFPAQLSGGQQQRVAIARALC 152
Cdd:COG4559 78 -AVLPQHSSLaFP-------FTVEEVVALGRaphgsSAAQDRQIVREALALVGLAHLAGRSYQTLSGGEQQRVQLARVLA 149
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446554041 153 -------MDPIAMLFDEPTSALDPEMINEVLDVMVELANEGMTMMVVTHEMGFARKVANRVIFMDEGKII-EDSPKDAF 223
Cdd:COG4559 150 qlwepvdGGPRWLFLDEPTSALDLAHQHAVLRLARQLARRGGGVVAVLHDLNLAAQYADRILLLHQGRLVaQGTPEEVL 228
|
|
| hmuV |
PRK13548 |
hemin importer ATP-binding subunit; Provisional |
1-223 |
3.24e-31 |
|
hemin importer ATP-binding subunit; Provisional
Pssm-ID: 237422 [Multi-domain] Cd Length: 258 Bit Score: 115.25 E-value: 3.24e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 1 MITLKNVSKWYGHFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNG-LEPvQQGEITVDGIVVND-KKTDLAKLRsr 78
Cdd:PRK13548 2 MLEARNLSVRLGGRTLLDDVSLTLRPGEVVAILGPNGAGKSTLLRALSGeLSP-DSGEVRLNGRPLADwSPAELARRR-- 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 79 vGMVFQHFEL-FPhlsiienLTLAQVkV------LKRNKAPAREKALKLLERVGLSAHANKFPAQLSGGQQQRVAIARAL 151
Cdd:PRK13548 79 -AVLPQHSSLsFP-------FTVEEV-VamgrapHGLSRAEDDALVAAALAQVDLAHLAGRDYPQLSGGEQQRVQLARVL 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 152 C------MDPIAMLFDEPTSALDPEMINEVLDVMVELANE-GMTMMVVTHEMGFARKVANRVIFMDEGKII-EDSPKDAF 223
Cdd:PRK13548 150 AqlwepdGPPRWLLLDEPTSALDLAHQHHVLRLARQLAHErGLAVIVVLHDLNLAARYADRIVLLHQGRLVaDGTPAEVL 229
|
|
| PRK14271 |
PRK14271 |
phosphate ABC transporter ATP-binding protein; Provisional |
34-237 |
8.11e-31 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172759 [Multi-domain] Cd Length: 276 Bit Score: 114.81 E-value: 8.11e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEPV-----QQGEITVDGIVVNDKKtDLAKLRSRVGMVFQHFELFPhLSIIENLtLAQVKVLK- 107
Cdd:PRK14271 54 GPTGSGKTTFLRTLNRMNDKvsgyrYSGDVLLGGRSIFNYR-DVLEFRRRVGMLFQRPNPFP-MSIMDNV-LAGVRAHKl 130
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 108 ------RNKAPAREKALKLLERVglSAHANKFPAQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLDVMVE 181
Cdd:PRK14271 131 vprkefRGVAQARLTEVGLWDAV--KDRLSDSPFRLSGGQQQLLCLARTLAVNPEVLLLDEPTSALDPTTTEKIEEFIRS 208
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 446554041 182 LANEgMTMMVVTHEMGFARKVANRVIFMDEGKIIEDSPKDAFFDNPKSDRAKDFLA 237
Cdd:PRK14271 209 LADR-LTVIIVTHNLAQAARISDRAALFFDGRLVEEGPTEQLFSSPKHAETARYVA 263
|
|
| cbiO |
PRK13640 |
energy-coupling factor transporter ATPase; |
34-223 |
9.55e-31 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184200 [Multi-domain] Cd Length: 282 Bit Score: 114.90 E-value: 9.55e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGL---EPVQQGEITVDGIVVNDKktDLAKLRSRVGMVFQHfelfPHLSIIENLTLAQVKVLKRNK 110
Cdd:PRK13640 40 GHNGSGKSTISKLINGLllpDDNPNSKITVDGITLTAK--TVWDIREKVGIVFQN----PDNQFVGATVGDDVAFGLENR 113
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 111 APAREKALKL----LERVGLSAHANKFPAQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLDVMVELANE- 185
Cdd:PRK13640 114 AVPRPEMIKIvrdvLADVGMLDYIDSEPANLSGGQKQRVAIAGILAVEPKIIILDESTSMLDPAGKEQILKLIRKLKKKn 193
|
170 180 190
....*....|....*....|....*....|....*....
gi 446554041 186 GMTMMVVTHEMGFArKVANRVIFMDEGKII-EDSPKDAF 223
Cdd:PRK13640 194 NLTVISITHDIDEA-NMADQVLVLDDGKLLaQGSPVEIF 231
|
|
| cbiO |
PRK13644 |
energy-coupling factor transporter ATPase; |
1-225 |
2.36e-30 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 106587 [Multi-domain] Cd Length: 274 Bit Score: 113.54 E-value: 2.36e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 1 MITLKNVSKWYGH-FQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVNDKkTDLAKLRSRV 79
Cdd:PRK13644 1 MIRLENVSYSYPDgTPALENINLVIKKGEYIGIIGKNGSGKSTLALHLNGLLRPQKGKVLVSGIDTGDF-SKLQGIRKLV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 80 GMVFQHfelfPHLSII------------ENLTLAQVKVLKRNKaparekalKLLERVGLSAHANKFPAQLSGGQQQRVAI 147
Cdd:PRK13644 80 GIVFQN----PETQFVgrtveedlafgpENLCLPPIEIRKRVD--------RALAEIGLEKYRHRSPKTLSGGQGQCVAL 147
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446554041 148 ARALCMDPIAMLFDEPTSALDPEMINEVLDVMVELANEGMTMMVVTHEMGfARKVANRVIFMDEGKII-EDSPKDAFFD 225
Cdd:PRK13644 148 AGILTMEPECLIFDEVTSMLDPDSGIAVLERIKKLHEKGKTIVYITHNLE-ELHDADRIIVMDRGKIVlEGEPENVLSD 225
|
|
| livG |
PRK11300 |
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional |
34-232 |
3.19e-30 |
|
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional
Pssm-ID: 183080 [Multi-domain] Cd Length: 255 Bit Score: 112.78 E-value: 3.19e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEPVQQGEITVDGivvndkkTDLAKLRS----RVGMV--FQHFELFPHLSIIENLTLAQVKVLK 107
Cdd:PRK11300 38 GPNGAGKTTVFNCLTGFYKPTGGTILLRG-------QHIEGLPGhqiaRMGVVrtFQHVRLFREMTVIENLLVAQHQQLK 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 108 RN------KAP--------AREKALKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMIN 173
Cdd:PRK11300 111 TGlfsgllKTPafrraeseALDRAATWLERVGLLEHANRQAGNLAYGQQRRLEIARCMVTQPEILMLDEPAAGLNPKETK 190
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 174 EVLDVMVELANE-GMTMMVVTHEMGFARKVANRVIFMDEGKIIEDSPKDAFFDNPKSDRA 232
Cdd:PRK11300 191 ELDELIAELRNEhNVTVLLIEHDMKLVMGISDRIYVVNQGTPLANGTPEEIRNNPDVIKA 250
|
|
| ABCC_ATM1_transporter |
cd03253 |
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC ... |
2-216 |
3.63e-30 |
|
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC transporter that is expressed in the mitochondria. Although the specific function of ATM1 is unknown, its disruption results in the accumulation of excess mitochondrial iron, loss of mitochondrial cytochromes, oxidative damage to mitochondrial DNA, and decreased levels of cytosolic heme proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213220 [Multi-domain] Cd Length: 236 Bit Score: 111.94 E-value: 3.63e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 2 ITLKNVSKWYG-HFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVndKKTDLAKLRSRVG 80
Cdd:cd03253 1 IEFENVTFAYDpGRPVLKDVSFTIPAGKKVAIVGPSGSGKSTILRLLFRFYDVSSGSILIDGQDI--REVTLDSLRRAIG 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 81 MVFQHFELFpHLSIIENLTLAQVKVLKRNKAPAREKAlKLLERVglsahaNKFPAQ-----------LSGGQQQRVAIAR 149
Cdd:cd03253 79 VVPQDTVLF-NDTIGYNIRYGRPDATDEEVIEAAKAA-QIHDKI------MRFPDGydtivgerglkLSGGEKQRVAIAR 150
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446554041 150 ALCMDPIAMLFDEPTSALDPEMINEVLDVMVELANeGMTMMVVTHEMgfaRKVAN--RVIFMDEGKIIE 216
Cdd:cd03253 151 AILKNPPILLLDEATSALDTHTEREIQAALRDVSK-GRTTIVIAHRL---STIVNadKIIVLKDGRIVE 215
|
|
| CydC |
TIGR02868 |
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family ... |
34-194 |
4.27e-30 |
|
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex.
Pssm-ID: 274331 [Multi-domain] Cd Length: 530 Bit Score: 117.08 E-value: 4.27e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVNDKKTDLakLRSRVGMVFQHFELFpHLSIIENLTLAqvkvlkRNKAPA 113
Cdd:TIGR02868 368 GPSGSGKSTLLATLAGLLDPLQGEVTLDGVPVSSLDQDE--VRRRVSVCAQDAHLF-DTTVRENLRLA------RPDATD 438
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 114 rEKALKLLERVGLSAHANKFP-----------AQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLDVMVEl 182
Cdd:TIGR02868 439 -EELWAALERVGLADWLRALPdgldtvlgeggARLSGGERQRLALARALLADAPILLLDEPTEHLDAETADELLEDLLA- 516
|
170
....*....|..
gi 446554041 183 ANEGMTMMVVTH 194
Cdd:TIGR02868 517 ALSGRTVVLITH 528
|
|
| ABC_MTABC3_MDL1_MDL2 |
cd03249 |
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 ... |
33-216 |
4.28e-30 |
|
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 (also known as ABCB6) is a mitochondrial ATP-binding cassette protein involved in iron homeostasis and one of four ABC transporters expressed in the mitochondrial inner membrane, the other three being MDL1(ABC7), MDL2, and ATM1. In fact, the yeast MDL1 (multidrug resistance-like protein 1) and MDL2 (multidrug resistance-like protein 2) transporters are also included in this CD. MDL1 is an ATP-dependent permease that acts as a high-copy suppressor of ATM1 and is thought to have a role in resistance to oxidative stress. Interestingly, subfamily B is more closely related to the carboxyl-terminal component of subfamily C than the two halves of ABCC molecules are with one another.
Pssm-ID: 213216 [Multi-domain] Cd Length: 238 Bit Score: 111.86 E-value: 4.28e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 33 CGPSGSGKSTLIKTVNGLEPVQQGEITVDGivVNDKKTDLAKLRSRVGMVFQHFELFPhLSIIENLTLAqvkvlkRNKAP 112
Cdd:cd03249 35 VGSSGCGKSTVVSLLERFYDPTSGEILLDG--VDIRDLNLRWLRSQIGLVSQEPVLFD-GTIAENIRYG------KPDAT 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 113 A--REKALKLLErvglsAHA--NKFP-----------AQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPE---MINE 174
Cdd:cd03249 106 DeeVEEAAKKAN-----IHDfiMSLPdgydtlvgergSQLSGGQKQRIAIARALLRNPKILLLDEATSALDAEsekLVQE 180
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 446554041 175 VLDvmveLANEGMTMMVVTHEMGFARKvANRVIFMDEGKIIE 216
Cdd:cd03249 181 ALD----RAMKGRTTIVIAHRLSTIRN-ADLIAVLQNGQVVE 217
|
|
| PRK14258 |
PRK14258 |
phosphate ABC transporter ATP-binding protein; Provisional |
2-236 |
4.99e-30 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 184593 [Multi-domain] Cd Length: 261 Bit Score: 112.44 E-value: 4.99e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 2 ITLKNVSKWYGHFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQqGEITVDGIV------VNDKKTDLAKL 75
Cdd:PRK14258 8 IKVNNLSFYYDTQKILEGVSMEIYQSKVTAIIGPSGCGKSTFLKCLNRMNELE-SEVRVEGRVeffnqnIYERRVNLNRL 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 76 RSRVGMVFQHFELFPhLSIIENLTLAqVKVL----KRNKAPAREKALK---LLERVGLSAHanKFPAQLSGGQQQRVAIA 148
Cdd:PRK14258 87 RRQVSMVHPKPNLFP-MSVYDNVAYG-VKIVgwrpKLEIDDIVESALKdadLWDEIKHKIH--KSALDLSGGQQQRLCIA 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 149 RALCMDPIAMLFDEPTSALDP--EMINEVLDVMVELANEgMTMMVVTHEMGFARKVANRVIFMDE-----GKIIEDSPKD 221
Cdd:PRK14258 163 RALAVKPKVLLMDEPCFGLDPiaSMKVESLIQSLRLRSE-LTMVIVSHNLHQVSRLSDFTAFFKGnenriGQLVEFGLTK 241
|
250
....*....|....*
gi 446554041 222 AFFDNPKSDRAKDFL 236
Cdd:PRK14258 242 KIFNSPHDSRTREYV 256
|
|
| ABCC_Protease_Secretion |
cd03246 |
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of ... |
34-214 |
6.41e-30 |
|
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of the protease secretion system PrtD, a 60-kDa integral membrane protein sharing 37% identity with HlyB, the ABC component of the alpha-hemolysin secretion pathway, in the C-terminal domain. They export degradative enzymes by using a type I protein secretion system and lack an N-terminal signal peptide, but contain a C-terminal secretion signal. The Type I secretion apparatus is made up of three components, an ABC transporter, a membrane fusion protein (MFP), and an outer membrane protein (OMP). For the HlyA transporter complex, HlyB (ABC transporter) and HlyD (MFP) reside in the inner membrane of E. coli. The OMP component is TolC, which is thought to interact with the MFP to form a continuous channel across the periplasm from the cytoplasm to the exterior. HlyB belongs to the family of ABC transporters, which are ubiquitous, ATP-dependent transmembrane pumps or channels. The spectrum of transport substrates ranges from inorganic ions, nutrients such as amino acids, sugars, or peptides, hydrophobic drugs, to large polypeptides, such as HlyA.
Pssm-ID: 213213 [Multi-domain] Cd Length: 173 Bit Score: 109.61 E-value: 6.41e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVNdkKTDLAKLRSRVGMVFQHFELFPHlSIIENLtlaqvkvlkrnkapa 113
Cdd:cd03246 35 GPSGSGKSTLARLILGLLRPTSGRVRLDGADIS--QWDPNELGDHVGYLPQDDELFSG-SIAENI--------------- 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 114 rekalkllervglsahankfpaqLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEmiNE--VLDVMVELANEGMTMMV 191
Cdd:cd03246 97 -----------------------LSGGQRQRLGLARALYGNPRILVLDEPNSHLDVE--GEraLNQAIAALKAAGATRIV 151
|
170 180
....*....|....*....|...
gi 446554041 192 VTHEMGFARKvANRVIFMDEGKI 214
Cdd:cd03246 152 IAHRPETLAS-ADRILVLEDGRV 173
|
|
| CydD |
TIGR02857 |
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family ... |
33-209 |
1.02e-29 |
|
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex. Unfortunately, the gene symbol nomenclature adopted based on this operon in B. subtilis assigns cydC to the third gene in the operon where this gene is actually homologous to the E. coli cydD gene. We have chosen to name all homologs in this family in accordance with the precedence of publication of the E. coli name, CydD
Pssm-ID: 274323 [Multi-domain] Cd Length: 529 Bit Score: 115.85 E-value: 1.02e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 33 CGPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVNDkkTDLAKLRSRVGMVFQHFELFPHlSIIENLTLAqvkvlkRNKAP 112
Cdd:TIGR02857 354 VGPSGAGKSTLLNLLLGFVDPTEGSIAVNGVPLAD--ADADSWRDQIAWVPQHPFLFAG-TIAENIRLA------RPDAS 424
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 113 AREKAlKLLERVGLSAHANKFP-----------AQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLDVMVE 181
Cdd:TIGR02857 425 DAEIR-EALERAGLDEFVAALPqgldtpigeggAGLSGGQAQRLALARAFLRDAPLLLLDEPTAHLDAETEAEVLEALRA 503
|
170 180
....*....|....*....|....*...
gi 446554041 182 LAnEGMTMMVVTHEMGFARkVANRVIFM 209
Cdd:TIGR02857 504 LA-QGRTVLLVTHRLALAA-LADRIVVL 529
|
|
| PRK10261 |
PRK10261 |
glutathione transporter ATP-binding protein; Provisional |
34-239 |
2.07e-29 |
|
glutathione transporter ATP-binding protein; Provisional
Pssm-ID: 182342 [Multi-domain] Cd Length: 623 Bit Score: 115.72 E-value: 2.07e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVND-KKTDLAKLRSRVGMVFQ--HFELFPHL----SIIENLtlaQVKVL 106
Cdd:PRK10261 357 GESGSGKSTTGRALLRLVESQGGEIIFNGQRIDTlSPGKLQALRRDIQFIFQdpYASLDPRQtvgdSIMEPL---RVHGL 433
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 107 KRNKApAREKALKLLERVGL-SAHANKFPAQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLDVMVELANE 185
Cdd:PRK10261 434 LPGKA-AAARVAWLLERVGLlPEHAWRYPHEFSGGQRQRICIARALALNPKVIIADEAVSALDVSIRGQIINLLLDLQRD 512
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 446554041 186 -GMTMMVVTHEMGFARKVANRVIFMDEGKIIEDSPKDAFFDNPKSDRAKDFLAKI 239
Cdd:PRK10261 513 fGIAYLFISHDMAVVERISHRVAVMYLGQIVEIGPRRAVFENPQHPYTRKLMAAV 567
|
|
| met_CoM_red_A2 |
TIGR03269 |
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ... |
1-216 |
2.24e-29 |
|
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]
Pssm-ID: 132313 [Multi-domain] Cd Length: 520 Bit Score: 114.90 E-value: 2.24e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 1 MITLKNVSKWY-----GHFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQQGEITVdgiVVNDKKTDLAKL 75
Cdd:TIGR03269 279 IIKVRNVSKRYisvdrGVVKAVDNVSLEVKEGEIFGIVGTSGAGKTTLSKIIAGVLEPTSGEVNV---RVGDEWVDMTKP 355
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 76 ----RSRV----GMVFQHFELFPHLSIIENLTLAqvKVLKRNKAPAREKALKLLERVGLSAHA-----NKFPAQLSGGQQ 142
Cdd:TIGR03269 356 gpdgRGRAkryiGILHQEYDLYPHRTVLDNLTEA--IGLELPDELARMKAVITLKMVGFDEEKaeeilDKYPDELSEGER 433
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446554041 143 QRVAIARALCMDPIAMLFDEPTSALDPEMINEVLDVMVELANE-GMTMMVVTHEMGFARKVANRVIFMDEGKIIE 216
Cdd:TIGR03269 434 HRVALAQVLIKEPRIVILDEPTGTMDPITKVDVTHSILKAREEmEQTFIIVSHDMDFVLDVCDRAALMRDGKIVK 508
|
|
| PRK15134 |
PRK15134 |
microcin C ABC transporter ATP-binding protein YejF; Provisional |
34-227 |
2.91e-29 |
|
microcin C ABC transporter ATP-binding protein YejF; Provisional
Pssm-ID: 237917 [Multi-domain] Cd Length: 529 Bit Score: 114.80 E-value: 2.91e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEPVQ-----QGEITVDG--IVVNDKKTdLAKLR-SRVGMVFQH--FELFPhLSIIENlTLAQV 103
Cdd:PRK15134 42 GESGSGKSVTALSILRLLPSPpvvypSGDIRFHGesLLHASEQT-LRGVRgNKIAMIFQEpmVSLNP-LHTLEK-QLYEV 118
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 104 KVLKR--NKAPAREKALKLLERVGLSAHANK---FPAQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLDV 178
Cdd:PRK15134 119 LSLHRgmRREAARGEILNCLDRVGIRQAAKRltdYPHQLSGGERQRVMIAMALLTRPELLIADEPTTALDVSVQAQILQL 198
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 446554041 179 MVELANE-GMTMMVVTHEMGFARKVANRVIFMDEGKIIEDSPKDAFFDNP 227
Cdd:PRK15134 199 LRELQQElNMGLLFITHNLSIVRKLADRVAVMQNGRCVEQNRAATLFSAP 248
|
|
| PhnK |
COG1101 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
34-217 |
4.09e-29 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 440718 [Multi-domain] Cd Length: 264 Bit Score: 110.18 E-value: 4.09e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEPVQQGEITVDGivvndkkTDLAKL----RSR-VGMVFQHFEL--FPHLSIIENLTLAQVK-- 104
Cdd:COG1101 39 GSNGAGKSTLLNAIAGSLPPDSGSILIDG-------KDVTKLpeykRAKyIGRVFQDPMMgtAPSMTIEENLALAYRRgk 111
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 105 -------VLKRNKAPAREKaLKLLE---------RVGLsahankfpaqLSGGQQQRVAIARALCMDPIAMLFDEPTSALD 168
Cdd:COG1101 112 rrglrrgLTKKRRELFREL-LATLGlglenrldtKVGL----------LSGGQRQALSLLMATLTKPKLLLLDEHTAALD 180
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 446554041 169 PEMINEVLDVMVELANE-GMTMMVVTHEMGFARKVANRVIFMDEGKIIED 217
Cdd:COG1101 181 PKTAALVLELTEKIVEEnNLTTLMVTHNMEQALDYGNRLIMMHEGRIILD 230
|
|
| ABCG_White |
cd03234 |
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ... |
34-215 |
1.25e-28 |
|
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ABC transporters homologous to the Drosophila white gene, which acts as a dimeric importer for eye pigment precursors. The eye pigmentation of Drosophila is developed from the synthesis and deposition in the cells of red pigments, which are synthesized from guanine, and brown pigments, which are synthesized from tryptophan. The pigment precursors are encoded by the white, brown, and scarlet genes, respectively. Evidence from genetic and biochemical studies suggest that the White and Brown proteins function as heterodimers to import guanine, while the White and Scarlet proteins function to import tryptophan. However, a recent study also suggests that White may be involved in the transport of a metabolite, such as 3-hydroxykynurenine, across intracellular membranes. Mammalian ABC transporters belonging to the White subfamily (ABCG1, ABCG5, and ABCG8) have been shown to be involved in the regulation of lipid-trafficking mechanisms in macrophages, hepatocytes, and intestinal mucosa cells. ABCG1 (ABC8), the human homolog of the Drosophila white gene is induced in monocyte-derived macrophages during cholesterol influx mediated by acetylated low-density lipoprotein. It is possible that human ABCG1 forms heterodimers with several heterologous partners.
Pssm-ID: 213201 [Multi-domain] Cd Length: 226 Bit Score: 107.74 E-value: 1.25e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLepVQQGEITVDGIVVNDKKTDLAKLRSRVGMVFQHFELFPHLSIIENLTLAQV---KVLKRNK 110
Cdd:cd03234 40 GSSGSGKTTLLDAISGR--VEGGGTTSGQILFNGQPRKPDQFQKCVAYVRQDDILLPGLTVRETLTYTAIlrlPRKSSDA 117
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 111 APAREKALKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLDVMVELANEGMTMM 190
Cdd:cd03234 118 IRKKRVEDVLLRDLALTRIGGNLVKGISGGERRRVSIAVQLLWDPKVLILDEPTSGLDSFTALNLVSTLSQLARRNRIVI 197
|
170 180
....*....|....*....|....*...
gi 446554041 191 VVTHEMG---FarKVANRVIFMDEGKII 215
Cdd:cd03234 198 LTIHQPRsdlF--RLFDRILLLSSGEIV 223
|
|
| PRK11160 |
PRK11160 |
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed |
2-216 |
1.94e-28 |
|
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
Pssm-ID: 236865 [Multi-domain] Cd Length: 574 Bit Score: 112.61 E-value: 1.94e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 2 ITLKNVSKWY--GHFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVNDkkTDLAKLRSRV 79
Cdd:PRK11160 339 LTLNNVSFTYpdQPQPVLKGLSLQIKAGEKVALLGRTGCGKSTLLQLLTRAWDPQQGEILLNGQPIAD--YSEAALRQAI 416
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 80 GMVFQHFELFPHlSIIENLTLAqvkvlkrnKAPAREKALK-LLERVGLSAHANKFPA----------QLSGGQQQRVAIA 148
Cdd:PRK11160 417 SVVSQRVHLFSA-TLRDNLLLA--------APNASDEALIeVLQQVGLEKLLEDDKGlnawlgeggrQLSGGEQRRLGIA 487
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446554041 149 RALCMD-PIaMLFDEPTSALDPEMINEVLDVMVELAnEGMTMMVVTHemgfaRKVA----NRVIFMDEGKIIE 216
Cdd:PRK11160 488 RALLHDaPL-LLLDEPTEGLDAETERQILELLAEHA-QNKTVLMITH-----RLTGleqfDRICVMDNGQIIE 553
|
|
| AztA |
NF040873 |
zinc ABC transporter ATP-binding protein AztA; |
34-200 |
4.19e-28 |
|
zinc ABC transporter ATP-binding protein AztA;
Pssm-ID: 468810 [Multi-domain] Cd Length: 191 Bit Score: 105.39 E-value: 4.19e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEPVQQGEITVDGivvndkktdlaklRSRVGMVFQHFEL---FPhLSIIENLTL---AQVKVLK 107
Cdd:NF040873 25 GPNGSGKSTLLKVLAGVLRPTSGTVRRAG-------------GARVAYVPQRSEVpdsLP-LTVRDLVAMgrwARRGLWR 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 108 RNKAPAREKALKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLDVMVELANEGM 187
Cdd:NF040873 91 RLTRDDRAAVDDALERVGLADLAGRQLGELSGGQRQRALLAQGLAQEADLLLLDEPTTGLDAESRERIIALLAEEHARGA 170
|
170
....*....|...
gi 446554041 188 TMMVVTHEMGFAR 200
Cdd:NF040873 171 TVVVVTHDLELVR 183
|
|
| PRK13657 |
PRK13657 |
glucan ABC transporter ATP-binding protein/ permease; |
34-216 |
4.50e-28 |
|
glucan ABC transporter ATP-binding protein/ permease;
Pssm-ID: 184214 [Multi-domain] Cd Length: 588 Bit Score: 111.59 E-value: 4.50e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIktvNGLEPV---QQGEITVDGIVVNDkkTDLAKLRSRVGMVFQHFELFpHLSIIENL-------TLAQV 103
Cdd:PRK13657 368 GPTGAGKSTLI---NLLQRVfdpQSGRILIDGTDIRT--VTRASLRRNIAVVFQDAGLF-NRSIEDNIrvgrpdaTDEEM 441
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 104 KvlkrnKAPAREKALKLLER--VGLSAHANKFPAQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEM---INEVLD- 177
Cdd:PRK13657 442 R-----AAAERAQAHDFIERkpDGYDTVVGERGRQLSGGERQRLAIARALLKDPPILILDEATSALDVETeakVKAALDe 516
|
170 180 190
....*....|....*....|....*....|....*....
gi 446554041 178 VMvelanEGMTMMVVTHEMGFARKvANRVIFMDEGKIIE 216
Cdd:PRK13657 517 LM-----KGRTTFIIAHRLSTVRN-ADRILVFDNGRVVE 549
|
|
| PhnL |
COG4778 |
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion ... |
34-212 |
6.47e-28 |
|
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion transport and metabolism];
Pssm-ID: 443809 [Multi-domain] Cd Length: 229 Bit Score: 105.98 E-value: 6.47e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEPVQQGEITVDgivVNDKKTDLAKL---------RSRVGMVFQHFELFPHLS----IIENLTL 100
Cdd:COG4778 44 GPSGAGKSTLLKCIYGNYLPDSGSILVR---HDGGWVDLAQAspreilalrRRTIGYVSQFLRVIPRVSaldvVAEPLLE 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 101 AQVkvlkrNKAPAREKALKLLERVGLSAH-ANKFPAQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLDVM 179
Cdd:COG4778 121 RGV-----DREEARARARELLARLNLPERlWDLPPATFSGGEQQRVNIARGFIADPPLLLLDEPTASLDAANRAVVVELI 195
|
170 180 190
....*....|....*....|....*....|...
gi 446554041 180 VELANEGMTMMVVTHEMGFARKVANRVIFMDEG 212
Cdd:COG4778 196 EEAKARGTAIIGIFHDEEVREAVADRVVDVTPF 228
|
|
| CP_lyasePhnK |
TIGR02323 |
phosphonate C-P lyase system protein PhnK; Members of this family are the PhnK protein of C-P ... |
1-228 |
6.72e-28 |
|
phosphonate C-P lyase system protein PhnK; Members of this family are the PhnK protein of C-P lyase systems for utilization of phosphonates. These systems resemble phosphonatase-based systems in having a three component ABC transporter, where TIGR01097 is the permease, TIGR01098 is the phosphonates binding protein, and TIGR02315 is the ATP-binding cassette (ABC) protein. They differ, however, in having, typically, ten or more additional genes, many of which are believed to form a membrane-associated complex. This protein (PhnK) and the adjacent-encoded PhnL resemble transporter ATP-binding proteins but are suggested, based on mutatgenesis studies, to be part of this complex rather than part of a transporter per se. [Central intermediary metabolism, Phosphorus compounds]
Pssm-ID: 188208 [Multi-domain] Cd Length: 253 Bit Score: 106.84 E-value: 6.72e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 1 MITLKNVSKWYGHFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQQGEITV---DGIVVNDKKTDLAK--- 74
Cdd:TIGR02323 3 LLQVSGLSKSYGGGKGCRDVSFDLYPGEVLGIVGESGSGKSTLLGCLAGRLAPDHGTATYimrSGAELELYQLSEAErrr 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 75 -LRSRVGMVFQHFE--LFPHLSIIENLTLAQVKVLKRNKAPAREKALKLLERVGLS-AHANKFPAQLSGGQQQRVAIARA 150
Cdd:TIGR02323 83 lMRTEWGFVHQNPRdgLRMRVSAGANIGERLMAIGARHYGNIRATAQDWLEEVEIDpTRIDDLPRAFSGGMQQRLQIARN 162
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446554041 151 LCMDPIAMLFDEPTSALDPEMINEVLDVMVELANE-GMTMMVVTHEMGFARKVANRVIFMDEGKIIEDSPKDAFFDNPK 228
Cdd:TIGR02323 163 LVTRPRLVFMDEPTGGLDVSVQARLLDLLRGLVRDlGLAVIIVTHDLGVARLLAQRLLVMQQGRVVESGLTDQVLDDPQ 241
|
|
| PRK13536 |
PRK13536 |
nodulation factor ABC transporter ATP-binding protein NodI; |
2-221 |
7.09e-28 |
|
nodulation factor ABC transporter ATP-binding protein NodI;
Pssm-ID: 237419 [Multi-domain] Cd Length: 340 Bit Score: 108.38 E-value: 7.09e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 2 ITLKNVSKWYGHFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVNDKktdlAKL-RSRVG 80
Cdd:PRK13536 42 IDLAGVSKSYGDKAVVNGLSFTVASGECFGLLGPNGAGKSTIARMILGMTSPDAGKITVLGVPVPAR----ARLaRARIG 117
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 81 MVFQHFELFPHLSIIENLtLAQVKVLKRNKAPAREKALKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMDPIAMLF 160
Cdd:PRK13536 118 VVPQFDNLDLEFTVRENL-LVFGRYFGMSTREIEAVIPSLLEFARLESKADARVSDLSGGMKRRLTLARALINDPQLLIL 196
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446554041 161 DEPTSALDPEMINEVLDVMVELANEGMTMMVVTHEMGFARKVANRVIFMDEG-KIIEDSPKD 221
Cdd:PRK13536 197 DEPTTGLDPHARHLIWERLRSLLARGKTILLTTHFMEEAERLCDRLCVLEAGrKIAEGRPHA 258
|
|
| ABCG_EPDR |
cd03213 |
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette ... |
34-215 |
7.10e-28 |
|
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily; ABCG transporters are involved in eye pigment (EP) precursor transport, regulation of lipid-trafficking mechanisms, and pleiotropic drug resistance (DR). DR is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. Compared to other members of the ABC transporter subfamilies, the ABCG transporter family is composed of proteins that have an ATP-binding cassette domain at the N-terminus and a TM (transmembrane) domain at the C-terminus.
Pssm-ID: 213180 [Multi-domain] Cd Length: 194 Bit Score: 104.94 E-value: 7.10e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEPVQQ--GEITVDGIvvndkKTDLAKLRSRVGMVFQHFELFPHLSIIENLtlaqvkvlkrnka 111
Cdd:cd03213 42 GPSGAGKSTLLNALAGRRTGLGvsGEVLINGR-----PLDKRSFRKIIGYVPQDDILHPTLTVRETL------------- 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 112 parekalkllervglsahanKFPAQL---SGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLDVMVELANEGMT 188
Cdd:cd03213 104 --------------------MFAAKLrglSGGERKRVSIALELVSNPSLLFLDEPTSGLDSSSALQVMSLLRRLADTGRT 163
|
170 180 190
....*....|....*....|....*....|.
gi 446554041 189 MMVVTH----EMgFarKVANRVIFMDEGKII 215
Cdd:cd03213 164 IICSIHqpssEI-F--ELFDKLLLLSQGRVI 191
|
|
| CeuD |
COG4604 |
ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and ... |
1-221 |
1.48e-27 |
|
ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443654 [Multi-domain] Cd Length: 252 Bit Score: 105.55 E-value: 1.48e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 1 MITLKNVSKWYGHFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVNDKKT-DLAKlrsRV 79
Cdd:COG4604 1 MIEIKNVSKRYGGKVVLDDVSLTIPKGGITALIGPNGAGKSTLLSMISRLLPPDSGEVLVDGLDVATTPSrELAK---RL 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 80 GMVFQ--HF-------EL-----FPHLSiiENLTLA-QVKVlkrnkaparEKALKLLErvgLSAHANKFPAQLSGGQQQR 144
Cdd:COG4604 78 AILRQenHInsrltvrELvafgrFPYSK--GRLTAEdREII---------DEAIAYLD---LEDLADRYLDELSGGQRQR 143
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446554041 145 VAIARALCMDPIAMLFDEPTSALDPEMINEVLDVMVELANE-GMTMMVVTHEMGFARKVANRVIFMDEGKIIEDSPKD 221
Cdd:COG4604 144 AFIAMVLAQDTDYVLLDEPLNNLDMKHSVQMMKLLRRLADElGKTVVIVLHDINFASCYADHIVAMKDGRVVAQGTPE 221
|
|
| phnK |
PRK11701 |
phosphonate C-P lyase system protein PhnK; Provisional |
5-227 |
4.91e-27 |
|
phosphonate C-P lyase system protein PhnK; Provisional
Pssm-ID: 183280 [Multi-domain] Cd Length: 258 Bit Score: 104.62 E-value: 4.91e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 5 KNVSKWYGHFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQQGEITVDGivvNDKK-TDLAKL-------- 75
Cdd:PRK11701 10 RGLTKLYGPRKGCRDVSFDLYPGEVLGIVGESGSGKTTLLNALSARLAPDAGEVHYRM---RDGQlRDLYALseaerrrl 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 76 -RSRVGMVFQHFE--LFPHLS----IIENLtlaqVKVLKRNKAPAREKALKLLERVGL-SAHANKFPAQLSGGQQQRVAI 147
Cdd:PRK11701 87 lRTEWGFVHQHPRdgLRMQVSaggnIGERL----MAVGARHYGDIRATAGDWLERVEIdAARIDDLPTTFSGGMQQRLQI 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 148 ARALCMDPIAMLFDEPTSALDPEMINEVLDVMVELANE-GMTMMVVTHEMGFARKVANRVIFMDEGKIIEDSPKDAFFDN 226
Cdd:PRK11701 163 ARNLVTHPRLVFMDEPTGGLDVSVQARLLDLLRGLVRElGLAVVIVTHDLAVARLLAHRLLVMKQGRVVESGLTDQVLDD 242
|
.
gi 446554041 227 P 227
Cdd:PRK11701 243 P 243
|
|
| 3a01204 |
TIGR00955 |
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, ... |
34-240 |
6.11e-27 |
|
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273361 [Multi-domain] Cd Length: 617 Bit Score: 108.60 E-value: 6.11e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEP---VQQGEITVDGIVVNDKKtdlakLRSRVGMVFQHFELFPHLSIIENLTL-AQVKvLKRN 109
Cdd:TIGR00955 58 GSSGAGKTTLMNALAFRSPkgvKGSGSVLLNGMPIDAKE-----MRAISAYVQQDDLFIPTLTVREHLMFqAHLR-MPRR 131
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 110 --KAPAREKALKLLERVGLSAHANKF---PAQ---LSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLDVMVE 181
Cdd:TIGR00955 132 vtKKEKRERVDEVLQALGLRKCANTRigvPGRvkgLSGGERKRLAFASELLTDPPLLFCDEPTSGLDSFMAYSVVQVLKG 211
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446554041 182 LANEGMTMMVVTH-------EMgFarkvaNRVIFMDEGKII-EDSPKDA--FFDN-----PKSDRAKDFLAKIL 240
Cdd:TIGR00955 212 LAQKGKTIICTIHqpsselfEL-F-----DKIILMAEGRVAyLGSPDQAvpFFSDlghpcPENYNPADFYVQVL 279
|
|
| type_I_sec_HlyB |
TIGR01846 |
type I secretion system ABC transporter, HlyB family; Type I protein secretion is a system in ... |
34-216 |
8.32e-27 |
|
type I secretion system ABC transporter, HlyB family; Type I protein secretion is a system in some Gram-negative bacteria to export proteins (often proteases) across both inner and outer membranes to the extracellular medium. This is one of three proteins of the type I secretion apparatus. Targeted proteins are not cleaved at the N-terminus, but rather carry signals located toward the extreme C-terminus to direct type I secretion. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 273831 [Multi-domain] Cd Length: 694 Bit Score: 108.29 E-value: 8.32e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEPVQQGEITVDGivVNDKKTDLAKLRSRVGMVFQHFELFPHlSIIENLTLA--QVKVLKRNKA 111
Cdd:TIGR01846 490 GPSGSGKSTLTKLLQRLYTPQHGQVLVDG--VDLAIADPAWLRRQMGVVLQENVLFSR-SIRDNIALCnpGAPFEHVIHA 566
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 112 PAREKALKLLERV--GLSAHANKFPAQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLDVMVELAnEGMTM 189
Cdd:TIGR01846 567 AKLAGAHDFISELpqGYNTEVGEKGANLSGGQRQRIAIARALVGNPRILIFDEATSALDYESEALIMRNMREIC-RGRTV 645
|
170 180
....*....|....*....|....*..
gi 446554041 190 MVVTHEMGFARKvANRVIFMDEGKIIE 216
Cdd:TIGR01846 646 IIIAHRLSTVRA-CDRIIVLEKGQIAE 671
|
|
| ABCC_cytochrome_bd |
cd03247 |
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome ... |
2-217 |
1.03e-26 |
|
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome bd biogenesis. The CydC and CydD proteins are important for the formation of cytochrome bd terminal oxidase of E. coli and it has been proposed that they were necessary for biosynthesis of the cytochrome bd quinol oxidase and for periplasmic c-type cytochromes. CydCD were proposed to determine a heterooligomeric complex important for heme export into the periplasm or to be involved in the maintenance of the proper redox state of the periplasmic space. In Bacillus subtilis, the absence of CydCD does not affect the presence of halo-cytochrome c in the membrane and this observation suggests that CydCD proteins are not involved in the export of heme in this organism.
Pssm-ID: 213214 [Multi-domain] Cd Length: 178 Bit Score: 101.62 E-value: 1.03e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 2 ITLKNVSKWYGH--FQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNG-LEPvQQGEITVDGIVVNDKKtdlAKLRSR 78
Cdd:cd03247 1 LSINNVSFSYPEqeQQVLKNLSLELKQGEKIALLGRSGSGKSTLLQLLTGdLKP-QQGEITLDGVPVSDLE---KALSSL 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 79 VGMVFQHFELFphlsiienltlaqvkvlkrnkaparekALKLLERVGlsahankfpAQLSGGQQQRVAIARALCMDPIAM 158
Cdd:cd03247 77 ISVLNQRPYLF---------------------------DTTLRNNLG---------RRFSGGERQRLALARILLQDAPIV 120
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 159 LFDEPTSALDPEMINEVLDVMVELAnEGMTMMVVTHEM-GFARkvANRVIFMDEGKIIED 217
Cdd:cd03247 121 LLDEPTVGLDPITERQLLSLIFEVL-KDKTLIWITHHLtGIEH--MDKILFLENGKIIMQ 177
|
|
| PRK11831 |
PRK11831 |
phospholipid ABC transporter ATP-binding protein MlaF; |
1-239 |
1.64e-26 |
|
phospholipid ABC transporter ATP-binding protein MlaF;
Pssm-ID: 236997 [Multi-domain] Cd Length: 269 Bit Score: 103.31 E-value: 1.64e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 1 MITLKNVSKWYGHFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVND-KKTDLAKLRSRV 79
Cdd:PRK11831 7 LVDMRGVSFTRGNRCIFDNISLTVPRGKITAIMGPSGIGKTTLLRLIGGQIAPDHGEILFDGENIPAmSRSRLYTVRKRM 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 80 GMVFQHFELFPHLSIIENLTLAQVKVLKRNKAPAREKALKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMDPIAML 159
Cdd:PRK11831 87 SMLFQSGALFTDMNVFDNVAYPLREHTQLPAPLLHSTVMMKLEAVGLRGAAKLMPSELSGGMARRAALARAIALEPDLIM 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 160 FDEPTSALDPeminEVLDVMVELANE-----GMTMMVVTHEMGFARKVANRVIFMDEGKIIEDSPKDAFFDNPKSdRAKD 234
Cdd:PRK11831 167 FDEPFVGQDP----ITMGVLVKLISElnsalGVTCVVVSHDVPEVLSIADHAYIVADKKIVAHGSAQALQANPDP-RVRQ 241
|
....*
gi 446554041 235 FLAKI 239
Cdd:PRK11831 242 FLDGI 246
|
|
| ABC_YhbG |
cd03218 |
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the ... |
2-228 |
1.98e-26 |
|
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the YhbG family are similar to members of the Mj1267_LivG family, which is involved in the transport of branched-chain amino acids. The genes yhbG and yhbN are located in a single operon and may function together in cell envelope during biogenesis. YhbG is the putative ATP-binding cassette component and YhbN is the putative periplasmic-binding protein. Depletion of each gene product leads to growth arrest, irreversible cell damage and loss of viability in E. coli. The YhbG homolog (NtrA) is essential in Rhizobium meliloti, a symbiotic nitrogen-fixing bacterium.
Pssm-ID: 213185 [Multi-domain] Cd Length: 232 Bit Score: 102.24 E-value: 1.98e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 2 ITLKNVSKWYGHFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQQGEITVDGivvndkkTDLAKL----RS 77
Cdd:cd03218 1 LRAENLSKRYGKRKVVNGVSLSVKQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGKILLDG-------QDITKLpmhkRA 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 78 RVGMVF--QHFELFPHLSIIENLtLAQVKVLKRNKAPAREKALKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMDP 155
Cdd:cd03218 74 RLGIGYlpQEASIFRKLTVEENI-LAVLEIRGLSKKEREEKLEELLEEFHITHLRKSKASSLSGGERRRVEIARALATNP 152
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446554041 156 IAMLFDEPTSALDPEMINEVLDVMVELANEGMTMMVVTHEMGFARKVANRVIFMDEGKIIEDSPKDAFFDNPK 228
Cdd:cd03218 153 KFLLLDEPFAGVDPIAVQDIQKIIKILKDRGIGVLITDHNVRETLSITDRAYIIYEGKVLAEGTPEEIAANEL 225
|
|
| livF |
PRK11614 |
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF; |
1-226 |
2.28e-26 |
|
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;
Pssm-ID: 183231 [Multi-domain] Cd Length: 237 Bit Score: 102.26 E-value: 2.28e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 1 MITLKNVSKWYGHFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVNDKKTdlAK-LRSRV 79
Cdd:PRK11614 5 MLSFDKVSAHYGKIQALHEVSLHINQGEIVTLIGANGAGKTTLLGTLCGDPRATSGRIVFDGKDITDWQT--AKiMREAV 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 80 GMVFQHFELFPHLSIIENLTLAQVKVLKRNKAPAREKALKLLERvgLSAHANKFPAQLSGGQQQRVAIARALCMDPIAML 159
Cdd:PRK11614 83 AIVPEGRRVFSRMTVEENLAMGGFFAERDQFQERIKWVYELFPR--LHERRIQRAGTMSGGEQQMLAIGRALMSQPRLLL 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446554041 160 FDEPTSALDPEMINEVLDVMVELANEGMTMMVVTHEMGFARKVANRVIFMDEGKIIEDSPKDAFFDN 226
Cdd:PRK11614 161 LDEPSLGLAPIIIQQIFDTIEQLREQGMTIFLVEQNANQALKLADRGYVLENGHVVLEDTGDALLAN 227
|
|
| cbiO |
PRK13650 |
energy-coupling factor transporter ATPase; |
1-223 |
3.17e-26 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184209 [Multi-domain] Cd Length: 279 Bit Score: 102.89 E-value: 3.17e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 1 MITLKNVSKWYGHFQ---VLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVNDKktDLAKLRS 77
Cdd:PRK13650 4 IIEVKNLTFKYKEDQekyTLNDVSFHVKQGEWLSIIGHNGSGKSTTVRLIDGLLEAESGQIIIDGDLLTEE--NVWDIRH 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 78 RVGMVFQHfelfPHLSIIENLTLAQVKVLKRNKAPA----REKALKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCM 153
Cdd:PRK13650 82 KIGMVFQN----PDNQFVGATVEDDVAFGLENKGIPheemKERVNEALELVGMQDFKEREPARLSGGQKQRVAIAGAVAM 157
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446554041 154 DPIAMLFDEPTSALDPEMINEVLDVMVELANE-GMTMMVVTHEMGfarKVA--NRVIFMDEGKIIEDS-PKDAF 223
Cdd:PRK13650 158 RPKIIILDEATSMLDPEGRLELIKTIKGIRDDyQMTVISITHDLD---EVAlsDRVLVMKNGQVESTStPRELF 228
|
|
| ABC_Carb_Monos_II |
cd03215 |
Second domain of the ATP-binding cassette component of monosaccharide transport system; This ... |
34-214 |
3.91e-26 |
|
Second domain of the ATP-binding cassette component of monosaccharide transport system; This family represents domain II of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. In members of Carb_Monos family the single hydrophobic gene product forms a homodimer, while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.
Pssm-ID: 213182 [Multi-domain] Cd Length: 182 Bit Score: 100.20 E-value: 3.91e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVNDKKTDLAkLRSRVGMV---FQHFELFPHLSIIENLTLaqvkvlkrnk 110
Cdd:cd03215 33 GLVGNGQTELAEALFGLRPPASGEITLDGKPVTRRSPRDA-IRAGIAYVpedRKREGLVLDLSVAENIAL---------- 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 111 aparekalkllervglsahankfPAQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLDVMVELANEGMTMM 190
Cdd:cd03215 102 -----------------------SSLLSGGNQQKVVLARWLARDPRVLILDEPTRGVDVGAKAEIYRLIRELADAGKAVL 158
|
170 180
....*....|....*....|....
gi 446554041 191 VVTHEMGFARKVANRVIFMDEGKI 214
Cdd:cd03215 159 LISSELDELLGLCDRILVMYEGRI 182
|
|
| MsbA_lipidA |
TIGR02203 |
lipid A export permease/ATP-binding protein MsbA; This family consists of a single polypeptide ... |
34-216 |
4.72e-26 |
|
lipid A export permease/ATP-binding protein MsbA; This family consists of a single polypeptide chain transporter in the ATP-binding cassette (ABC) transporter family, MsbA, which exports lipid A. It may also act in multidrug resistance. Lipid A, a part of lipopolysaccharide, is found in the outer leaflet of the outer membrane of most Gram-negative bacteria. Members of this family are restricted to the Proteobacteria (although lipid A is more broadly distributed) and often are clustered with lipid A biosynthesis genes. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides, Transport and binding proteins, Other]
Pssm-ID: 131258 [Multi-domain] Cd Length: 571 Bit Score: 105.57 E-value: 4.72e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVNDKKtdLAKLRSRVGMVFQHFELFphlsiieNLTLAQVKVLKRNKAPA 113
Cdd:TIGR02203 365 GRSGSGKSTLVNLIPRFYEPDSGQILLDGHDLADYT--LASLRRQVALVSQDVVLF-------NDTIANNIAYGRTEQAD 435
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 114 REKALKLLERVGLSAHANKFP-----------AQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLDVMVEL 182
Cdd:TIGR02203 436 RAEIERALAAAYAQDFVDKLPlgldtpigengVLLSGGQRQRLAIARALLKDAPILILDEATSALDNESERLVQAALERL 515
|
170 180 190
....*....|....*....|....*....|....
gi 446554041 183 AnEGMTMMVVTHEMGFARKvANRVIFMDEGKIIE 216
Cdd:TIGR02203 516 M-QGRTTLVIAHRLSTIEK-ADRIVVMDDGRIVE 547
|
|
| MglA |
COG1129 |
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; |
37-215 |
6.06e-26 |
|
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440745 [Multi-domain] Cd Length: 497 Bit Score: 105.10 E-value: 6.06e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 37 GSGKSTLIKTVNGLEPVQQGEITVDGivvndKKTDLAKLRSRV--GMVF-----QHFELFPHLSIIENLTLAQVKVLKR- 108
Cdd:COG1129 288 GAGRTELARALFGADPADSGEIRLDG-----KPVRIRSPRDAIraGIAYvpedrKGEGLVLDLSIRENITLASLDRLSRg 362
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 109 ---NKAPAREKALKLLERVGLSAHANKFPAQ-LSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLDVMVELAN 184
Cdd:COG1129 363 gllDRRRERALAEEYIKRLRIKTPSPEQPVGnLSGGNQQKVVLAKWLATDPKVLILDEPTRGIDVGAKAEIYRLIRELAA 442
|
170 180 190
....*....|....*....|....*....|.
gi 446554041 185 EGMTMMVVTHEMGFARKVANRVIFMDEGKII 215
Cdd:COG1129 443 EGKAVIVISSELPELLGLSDRILVMREGRIV 473
|
|
| PRK13537 |
PRK13537 |
nodulation factor ABC transporter ATP-binding protein NodI; |
2-221 |
8.02e-26 |
|
nodulation factor ABC transporter ATP-binding protein NodI;
Pssm-ID: 237420 [Multi-domain] Cd Length: 306 Bit Score: 102.19 E-value: 8.02e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 2 ITLKNVSKWYGHFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVNDKKTdlaKLRSRVGM 81
Cdd:PRK13537 8 IDFRNVEKRYGDKLVVDGLSFHVQRGECFGLLGPNGAGKTTTLRMLLGLTHPDAGSISLCGEPVPSRAR---HARQRVGV 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 82 VFQHFELFPHLSIIENLtLAQVKVLKRNKAPAREKALKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMDPIAMLFD 161
Cdd:PRK13537 85 VPQFDNLDPDFTVRENL-LVFGRYFGLSAAAARALVPPLLEFAKLENKADAKVGELSGGMKRRLTLARALVNDPDVLVLD 163
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446554041 162 EPTSALDPEMINEVLDVMVELANEGMTMMVVTHEMGFARKVANRVIFMDEG-KIIEDSPKD 221
Cdd:PRK13537 164 EPTTGLDPQARHLMWERLRSLLARGKTILLTTHFMEEAERLCDRLCVIEEGrKIAEGAPHA 224
|
|
| ABCC_TAP |
cd03248 |
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; ... |
13-214 |
3.54e-25 |
|
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; TAP (Transporter Associated with Antigen Processing) is essential for peptide delivery from the cytosol into the lumen of the endoplasmic reticulum (ER), where these peptides are loaded on major histocompatibility complex (MHC) I molecules. Loaded MHC I leave the ER and display their antigenic cargo on the cell surface to cytotoxic T cells. Subsequently, virus-infected or malignantly transformed cells can be eliminated. TAP belongs to the large family of ATP-binding cassette (ABC) transporters, which translocate a vast variety of solutes across membranes.
Pssm-ID: 213215 [Multi-domain] Cd Length: 226 Bit Score: 98.70 E-value: 3.54e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 13 HFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVNDKKTDLakLRSRVGMVFQHFELFPHl 92
Cdd:cd03248 26 DTLVLQDVSFTLHPGEVTALVGPSGSGKSTVVALLENFYQPQGGQVLLDGKPISQYEHKY--LHSKVSLVGQEPVLFAR- 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 93 SIIENLT--LAQVKVLKRNKAPAREKA---LKLLERvGLSAHANKFPAQLSGGQQQRVAIARALCMDPIAMLFDEPTSAL 167
Cdd:cd03248 103 SLQDNIAygLQSCSFECVKEAAQKAHAhsfISELAS-GYDTEVGEKGSQLSGGQKQRVAIARALIRNPQVLILDEATSAL 181
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 446554041 168 DPEMiNEVLDVMVELANEGMTMMVVTHEMGFARKvANRVIFMDEGKI 214
Cdd:cd03248 182 DAES-EQQVQQALYDWPERRTVLVIAHRLSTVER-ADQILVLDGGRI 226
|
|
| PRK15079 |
PRK15079 |
oligopeptide ABC transporter ATP-binding protein OppF; Provisional |
34-228 |
3.57e-25 |
|
oligopeptide ABC transporter ATP-binding protein OppF; Provisional
Pssm-ID: 185037 [Multi-domain] Cd Length: 331 Bit Score: 100.94 E-value: 3.57e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEPVQQGEITVDGI-VVNDKKTDLAKLRSRVGMVFQH--FELFPHLS----IIENLTLAQVKVl 106
Cdd:PRK15079 54 GESGCGKSTFARAIIGLVKATDGEVAWLGKdLLGMKDDEWRAVRSDIQMIFQDplASLNPRMTigeiIAEPLRTYHPKL- 132
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 107 krNKAPAREKALKLLERVGLSAHA-NKFPAQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLDVMVELANE 185
Cdd:PRK15079 133 --SRQEVKDRVKAMMLKVGLLPNLiNRYPHEFSGGQCQRIGIARALILEPKLIICDEPVSALDVSIQAQVVNLLQQLQRE 210
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 446554041 186 -GMTMMVVTHEMGFARKVANRVIFMDEGKIIEDSPKDAFFDNPK 228
Cdd:PRK15079 211 mGLSLIFIAHDLAVVKHISDRVLVMYLGHAVELGTYDEVYHNPL 254
|
|
| fecE |
PRK11231 |
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE; |
1-215 |
3.69e-25 |
|
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;
Pssm-ID: 183044 [Multi-domain] Cd Length: 255 Bit Score: 99.32 E-value: 3.69e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 1 MITLKNVSKWYGHFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQQGEITVDGivvndkkTDLAKLRSRVg 80
Cdd:PRK11231 2 TLRTENLTVGYGTKRILNDLSLSLPTGKITALIGPNGCGKSTLLKCFARLLTPQSGTVFLGD-------KPISMLSSRQ- 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 81 mVFQHFELFP-HLSIIENLTLAQVKVLKRN-------KAPAREKAL--KLLERVGLSAHANKFPAQLSGGQQQRVAIARA 150
Cdd:PRK11231 74 -LARRLALLPqHHLTPEGITVRELVAYGRSpwlslwgRLSAEDNARvnQAMEQTRINHLADRRLTDLSGGQRQRAFLAMV 152
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446554041 151 LCMD-PIAMLfDEPTSALDpemIN---EVLDVMVELANEGMTMMVVTHEMGFARKVANRVIFMDEGKII 215
Cdd:PRK11231 153 LAQDtPVVLL-DEPTTYLD---INhqvELMRLMRELNTQGKTVVTVLHDLNQASRYCDHLVVLANGHVM 217
|
|
| NHLM_micro_ABC2 |
TIGR03797 |
NHLM bacteriocin system ABC transporter, ATP-binding protein; Members of this protein family ... |
2-216 |
4.64e-25 |
|
NHLM bacteriocin system ABC transporter, ATP-binding protein; Members of this protein family are ABC transporter ATP-binding subunits, part of a three-gene putative bacteriocin transport operon. The other subunits include another ATP-binding subunit (TIGR03796), which has an N-terminal leader sequence cleavage domain, and an HlyD homolog (TIGR03794). In a number of genomes, members of protein families related to nitrile hydratase alpha subunit or to nif11 have undergone paralogous family expansions, with members possessing a putative bacteriocin cleavage region ending with a classic Gly-Gly motif. Those sets of putative bacteriocins, members of this protein family and its partners TIGR03794 and TIGR03796, and cyclodehydratase/docking scaffold fusion proteins of thiazole/oxazole biosynthesis frequently show correlated species distribution and co-clustering within many of those genomes. [Transport and binding proteins, Amino acids, peptides and amines, Cellular processes, Biosynthesis of natural products]
Pssm-ID: 274789 [Multi-domain] Cd Length: 686 Bit Score: 103.11 E-value: 4.64e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 2 ITLKNVSKWYGH--FQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVndKKTDLAKLRSRV 79
Cdd:TIGR03797 452 IEVDRVTFRYRPdgPLILDDVSLQIEPGEFVAIVGPSGSGKSTLLRLLLGFETPESGSVFYDGQDL--AGLDVQAVRRQL 529
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 80 GMVFQHFELFPHlSIIENLTLAQVKVLKRNKAPARekalklleRVGLSAHANKFP-----------AQLSGGQQQRVAIA 148
Cdd:TIGR03797 530 GVVLQNGRLMSG-SIFENIAGGAPLTLDEAWEAAR--------MAGLAEDIRAMPmgmhtviseggGTLSGGQRQRLLIA 600
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446554041 149 RALCMDPIAMLFDEPTSALDPEMiNEVldVMVELANEGMTMMVVTHEMGFARKvANRVIFMDEGKIIE 216
Cdd:TIGR03797 601 RALVRKPRILLFDEATSALDNRT-QAI--VSESLERLKVTRIVIAHRLSTIRN-ADRIYVLDAGRVVQ 664
|
|
| PRK15112 |
PRK15112 |
peptide ABC transporter ATP-binding protein SapF; |
34-216 |
6.60e-25 |
|
peptide ABC transporter ATP-binding protein SapF;
Pssm-ID: 185067 [Multi-domain] Cd Length: 267 Bit Score: 99.09 E-value: 6.60e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVNdkKTDLAKLRSRVGMVFQ--HFELFPHLSIIENLTLAqvkvLKRN-- 109
Cdd:PRK15112 46 GENGSGKSTLAKMLAGMIEPTSGELLIDDHPLH--FGDYSYRSQRIRMIFQdpSTSLNPRQRISQILDFP----LRLNtd 119
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 110 -KAPAREKALKL-LERVGLSA-HANKFPAQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLDVMVEL-ANE 185
Cdd:PRK15112 120 lEPEQREKQIIEtLRQVGLLPdHASYYPHMLAPGQKQRLGLARALILRPKVIIADEALASLDMSMRSQLINLMLELqEKQ 199
|
170 180 190
....*....|....*....|....*....|.
gi 446554041 186 GMTMMVVTHEMGFARKVANRVIFMDEGKIIE 216
Cdd:PRK15112 200 GISYIYVTQHLGMMKHISDQVLVMHQGEVVE 230
|
|
| cbiO |
PRK13648 |
cobalt transporter ATP-binding subunit; Provisional |
1-225 |
8.06e-25 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184207 [Multi-domain] Cd Length: 269 Bit Score: 99.06 E-value: 8.06e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 1 MITLKNVSKWYGHFQVLT--DCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVNDKktDLAKLRSR 78
Cdd:PRK13648 7 IIVFKNVSFQYQSDASFTlkDVSFNIPKGQWTSIVGHNGSGKSTIAKLMIGIEKVKSGEIFYNNQAITDD--NFEKLRKH 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 79 VGMVFQHfelfPHLSIIENLTLAQVKV-LKRNKAP---AREKALKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMD 154
Cdd:PRK13648 85 IGIVFQN----PDNQFVGSIVKYDVAFgLENHAVPydeMHRRVSEALKQVDMLERADYEPNALSGGQKQRVAIAGVLALN 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446554041 155 PIAMLFDEPTSALDPEMINEVLDVMVEL-ANEGMTMMVVTHEMGFARKvANRVIFMDEGKIIED-SPKDAFFD 225
Cdd:PRK13648 161 PSVIILDEATSMLDPDARQNLLDLVRKVkSEHNITIISITHDLSEAME-ADHVIVMNKGTVYKEgTPTEIFDH 232
|
|
| met_CoM_red_A2 |
TIGR03269 |
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ... |
2-216 |
1.14e-24 |
|
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]
Pssm-ID: 132313 [Multi-domain] Cd Length: 520 Bit Score: 101.80 E-value: 1.14e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 2 ITLKNVSKWYGHFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLE--PVQQGEI--------------------- 58
Cdd:TIGR03269 1 IEVKNLTKKFDGKEVLKNISFTIEEGEVLGILGRSGAGKSVLMHVLRGMDqyEPTSGRIiyhvalcekcgyverpskvge 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 59 -------TVDGIVV---NDKKTDLAKLRSRVGMVFQH-FELFPHLSIIENLtlaqVKVLKRNKAPARE---KALKLLERV 124
Cdd:TIGR03269 81 pcpvcggTLEPEEVdfwNLSDKLRRRIRKRIAIMLQRtFALYGDDTVLDNV----LEALEEIGYEGKEavgRAVDLIEMV 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 125 GLSAHANKFPAQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLDVMVELA-NEGMTMMVVTHEMGFARKVA 203
Cdd:TIGR03269 157 QLSHRITHIARDLSGGEKQRVVLARQLAKEPFLFLADEPTGTLDPQTAKLVHNALEEAVkASGISMVLTSHWPEVIEDLS 236
|
250
....*....|...
gi 446554041 204 NRVIFMDEGKIIE 216
Cdd:TIGR03269 237 DKAIWLENGEIKE 249
|
|
| cbiO |
PRK13652 |
cobalt transporter ATP-binding subunit; Provisional |
34-227 |
1.19e-24 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 172200 [Multi-domain] Cd Length: 277 Bit Score: 98.72 E-value: 1.19e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVNdkKTDLAKLRSRVGMVFQHFELFPHLSIIE--------NLTLAQVKV 105
Cdd:PRK13652 37 GPNGAGKSTLFRHFNGILKPTSGSVLIRGEPIT--KENIREVRKFVGLVFQNPDDQIFSPTVEqdiafgpiNLGLDEETV 114
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 106 LKRnkapaREKALKLLervGLSAHANKFPAQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLDVMVELANE 185
Cdd:PRK13652 115 AHR-----VSSALHML---GLEELRDRVPHHLSGGEKKRVAIAGVIAMEPQVLVLDEPTAGLDPQGVKELIDFLNDLPET 186
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 446554041 186 -GMTMMVVTHEMGFARKVANRVIFMDEGKIIEDSPKDAFFDNP 227
Cdd:PRK13652 187 yGMTVIFSTHQLDLVPEMADYIYVMDKGRIVAYGTVEEIFLQP 229
|
|
| PRK11176 |
PRK11176 |
lipid A ABC transporter ATP-binding protein/permease MsbA; |
34-216 |
2.28e-24 |
|
lipid A ABC transporter ATP-binding protein/permease MsbA;
Pssm-ID: 183016 [Multi-domain] Cd Length: 582 Bit Score: 100.86 E-value: 2.28e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVNDKKtdLAKLRSRVGMVFQHFELFphlsiieNLTLAQVKVLKRNKAPA 113
Cdd:PRK11176 376 GRSGSGKSTIANLLTRFYDIDEGEILLDGHDLRDYT--LASLRNQVALVSQNVHLF-------NDTIANNIAYARTEQYS 446
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 114 REKalklLERVGLSAHANKF---------------PAQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPE---MINEV 175
Cdd:PRK11176 447 REQ----IEEAARMAYAMDFinkmdngldtvigenGVLLSGGQRQRIAIARALLRDSPILILDEATSALDTEserAIQAA 522
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 446554041 176 LDvmvELANEgMTMMVVTHEMGFARKvANRVIFMDEGKIIE 216
Cdd:PRK11176 523 LD---ELQKN-RTSLVIAHRLSTIEK-ADEILVVEDGEIVE 558
|
|
| PRK09700 |
PRK09700 |
D-allose ABC transporter ATP-binding protein AlsA; |
1-212 |
2.92e-24 |
|
D-allose ABC transporter ATP-binding protein AlsA;
Pssm-ID: 182036 [Multi-domain] Cd Length: 510 Bit Score: 100.24 E-value: 2.92e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 1 MITLKNVSKWYGHFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVNDKKTDLAKlRSRVG 80
Cdd:PRK09700 5 YISMAGIGKSFGPVHALKSVNLTVYPGEIHALLGENGAGKSTLMKVLSGIHEPTKGTITINNINYNKLDHKLAA-QLGIG 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 81 MVFQHFELFPHLSIIENLTLAQVKVLKRNKAPA------REKALKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMD 154
Cdd:PRK09700 84 IIYQELSVIDELTVLENLYIGRHLTKKVCGVNIidwremRVRAAMMLLRVGLKVDLDEKVANLSISHKQMLEIAKTLMLD 163
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 446554041 155 PIAMLFDEPTSALDPEMINEVLDVMVELANEGMTMMVVTHEMGFARKVANRVIFMDEG 212
Cdd:PRK09700 164 AKVIIMDEPTSSLTNKEVDYLFLIMNQLRKEGTAIVYISHKLAEIRRICDRYTVMKDG 221
|
|
| GguA |
NF040905 |
sugar ABC transporter ATP-binding protein; |
33-216 |
3.00e-24 |
|
sugar ABC transporter ATP-binding protein;
Pssm-ID: 468840 [Multi-domain] Cd Length: 500 Bit Score: 100.25 E-value: 3.00e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 33 CGPSGSGKSTLIKTVNGLEP--VQQGEITVDGIVVNDKktdlaKLRS--RVGMVFQHFE--LFPHLSIIENLTL----AQ 102
Cdd:NF040905 33 CGENGAGKSTLMKVLSGVYPhgSYEGEILFDGEVCRFK-----DIRDseALGIVIIHQElaLIPYLSIAENIFLgnerAK 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 103 VKVLKRNKapAREKALKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLDVMVEL 182
Cdd:NF040905 108 RGVIDWNE--TNRRARELLAKVGLDESPDTLVTDIGVGKQQLVEIAKALSKDVKLLILDEPTAALNEEDSAALLDLLLEL 185
|
170 180 190
....*....|....*....|....*....|....
gi 446554041 183 ANEGMTMMVVTHEMGFARKVANRVIFMDEGKIIE 216
Cdd:NF040905 186 KAQGITSIIISHKLNEIRRVADSITVLRDGRTIE 219
|
|
| PRK15134 |
PRK15134 |
microcin C ABC transporter ATP-binding protein YejF; Provisional |
34-237 |
4.64e-24 |
|
microcin C ABC transporter ATP-binding protein YejF; Provisional
Pssm-ID: 237917 [Multi-domain] Cd Length: 529 Bit Score: 99.78 E-value: 4.64e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKST----LIKTVNglepvQQGEITVDGIVVND-KKTDLAKLRSRVGMVFQ--HFELFPHLS----IIENLTLAQ 102
Cdd:PRK15134 319 GESGSGKSTtglaLLRLIN-----SQGEIWFDGQPLHNlNRRQLLPVRHRIQVVFQdpNSSLNPRLNvlqiIEEGLRVHQ 393
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 103 vKVLkrNKAPAREKALKLLERVGLSAHA-NKFPAQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLDVMVE 181
Cdd:PRK15134 394 -PTL--SAAQREQQVIAVMEEVGLDPETrHRYPAEFSGGQRQRIAIARALILKPSLIILDEPTSSLDKTVQAQILALLKS 470
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 446554041 182 LANE-GMTMMVVTHEMGFARKVANRVIFMDEGKIIEDSPKDAFFDNPKSDRAKDFLA 237
Cdd:PRK15134 471 LQQKhQLAYLFISHDLHVVRALCHQVIVLRQGEVVEQGDCERVFAAPQQEYTRQLLA 527
|
|
| btuD |
PRK09536 |
corrinoid ABC transporter ATPase; Reviewed |
1-214 |
2.10e-23 |
|
corrinoid ABC transporter ATPase; Reviewed
Pssm-ID: 236554 [Multi-domain] Cd Length: 402 Bit Score: 97.22 E-value: 2.10e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 1 MITLKNVSKWYGHFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVndKKTDLAKLRSRVG 80
Cdd:PRK09536 3 MIDVSDLSVEFGDTTVLDGVDLSVREGSLVGLVGPNGAGKTTLLRAINGTLTPTAGTVLVAGDDV--EALSARAASRRVA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 81 MVFQH----FEL----------FPHLSIIENLTLAQVKVLKRnkaparekalkLLERVGLSAHANKFPAQLSGGQQQRVA 146
Cdd:PRK09536 81 SVPQDtslsFEFdvrqvvemgrTPHRSRFDTWTETDRAAVER-----------AMERTGVAQFADRPVTSLSGGERQRVL 149
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446554041 147 IARALCMDPIAMLFDEPTSALDPEMINEVLDVMVELANEGMTMMVVTHEMGFARKVANRVIFMDEGKI 214
Cdd:PRK09536 150 LARALAQATPVLLLDEPTASLDINHQVRTLELVRRLVDDGKTAVAAIHDLDLAARYCDELVLLADGRV 217
|
|
| dppD |
PRK11022 |
dipeptide transporter ATP-binding subunit; Provisional |
34-228 |
2.60e-23 |
|
dipeptide transporter ATP-binding subunit; Provisional
Pssm-ID: 182906 [Multi-domain] Cd Length: 326 Bit Score: 95.96 E-value: 2.60e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLepvqqgeITVDGIVVNDK----KTDLAKLRSR---------VGMVFQH--FELFPHLS----I 94
Cdd:PRK11022 40 GESGSGKSVSSLAIMGL-------IDYPGRVMAEKlefnGQDLQRISEKerrnlvgaeVAMIFQDpmTSLNPCYTvgfqI 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 95 IENLTLAQvkvlKRNKAPAREKALKLLERVGLSAHANK---FPAQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEM 171
Cdd:PRK11022 113 MEAIKVHQ----GGNKKTRRQRAIDLLNQVGIPDPASRldvYPHQLSGGMSQRVMIAMAIACRPKLLIADEPTTALDVTI 188
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 446554041 172 INEVLDVMVELAN-EGMTMMVVTHEMGFARKVANRVIFMDEGKIIEDSPKDAFFDNPK 228
Cdd:PRK11022 189 QAQIIELLLELQQkENMALVLITHDLALVAEAAHKIIVMYAGQVVETGKAHDIFRAPR 246
|
|
| ArpD |
COG4618 |
ABC-type protease/lipase transport system, ATPase and permease components [Intracellular ... |
34-221 |
4.33e-23 |
|
ABC-type protease/lipase transport system, ATPase and permease components [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 443660 [Multi-domain] Cd Length: 563 Bit Score: 97.13 E-value: 4.33e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVND-KKTDLAKLrsrVGMVFQHFELFPHlSIIENLTlaqvkvlkRNKAP 112
Cdd:COG4618 365 GPSGSGKSTLARLLVGVWPPTAGSVRLDGADLSQwDREELGRH---IGYLPQDVELFDG-TIAENIA--------RFGDA 432
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 113 AREKALKLLERVGlsAHA--NKFP-----------AQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLDVM 179
Cdd:COG4618 433 DPEKVVAAAKLAG--VHEmiLRLPdgydtrigeggARLSGGQRQRIGLARALYGDPRLVVLDEPNSNLDDEGEAALAAAI 510
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 446554041 180 VELANEGMTMMVVTHEMGFARkVANRVIFMDEGKIIEDSPKD 221
Cdd:COG4618 511 RALKARGATVVVITHRPSLLA-AVDKLLVLRDGRVQAFGPRD 551
|
|
| PRK15056 |
PRK15056 |
manganese/iron ABC transporter ATP-binding protein; |
34-232 |
8.44e-23 |
|
manganese/iron ABC transporter ATP-binding protein;
Pssm-ID: 185016 [Multi-domain] Cd Length: 272 Bit Score: 93.41 E-value: 8.44e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVNDkktdlAKLRSRVGMVFQHFEL---FPHLsiIENLTL----AQVKVL 106
Cdd:PRK15056 40 GVNGSGKSTLFKALMGFVRLASGKISILGQPTRQ-----ALQKNLVAYVPQSEEVdwsFPVL--VEDVVMmgryGHMGWL 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 107 KRNKAPAREKALKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLDVMVELANEG 186
Cdd:PRK15056 113 RRAKKRDRQIVTAALARVDMVEFRHRQIGELSGGQKKRVFLARAIAQQGQVILLDEPFTGVDVKTEARIISLLRELRDEG 192
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 446554041 187 MTMMVVTHEMGFARKVANRVIfMDEGKIIEDSPKDAFFDNPKSDRA 232
Cdd:PRK15056 193 KTMLVSTHNLGSVTEFCDYTV-MVKGTVLASGPTETTFTAENLELA 237
|
|
| Uup |
COG0488 |
ATPase components of ABC transporters with duplicated ATPase domains [General function ... |
1-216 |
9.50e-23 |
|
ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];
Pssm-ID: 440254 [Multi-domain] Cd Length: 520 Bit Score: 95.90 E-value: 9.50e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 1 MITLKNVSKWYGHFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQQGEITVdGIVVndkktdlaklrsRVG 80
Cdd:COG0488 315 VLELEGLSKSYGDKTLLDDLSLRIDRGDRIGLIGPNGAGKSTLLKLLAGELEPDSGTVKL-GETV------------KIG 381
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 81 MVFQHFELF-PHLSIIENLtlaqvkvlkRNKAPA--REKALKLLERVGLS-AHANKFPAQLSGGQQQRVAIARALCMDPI 156
Cdd:COG0488 382 YFDQHQEELdPDKTVLDEL---------RDGAPGgtEQEVRGYLGRFLFSgDDAFKPVGVLSGGEKARLALAKLLLSPPN 452
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446554041 157 AMLFDEPTSALDPEMINEVLDVmveLAN-EGmTMMVVTHEMGFARKVANRVIFMDEGKIIE 216
Cdd:COG0488 453 VLLLDEPTNHLDIETLEALEEA---LDDfPG-TVLLVSHDRYFLDRVATRILEFEDGGVRE 509
|
|
| bacteriocin_ABC |
TIGR01193 |
ABC-type bacteriocin transporter; This model describes ABC-type bacteriocin transporter. The ... |
2-241 |
1.74e-22 |
|
ABC-type bacteriocin transporter; This model describes ABC-type bacteriocin transporter. The amino terminal domain (pfam03412) processes the N-terminal leader peptide from the bacteriocin while C-terminal domains resemble ABC transporter membrane protein and ATP-binding cassette domain. In general, bacteriocins are agents which are responsible for killing or inhibiting the closely related species or even different strains of the same species. Bacteriocins are usually encoded by bacterial plasmids. Bacteriocins are named after the species and hence in literature one encounters various names e.g., leucocin from Leuconostic geldium; pedicocin from Pedicoccus acidilactici; sakacin from Lactobacillus sake etc. [Protein fate, Protein and peptide secretion and trafficking, Protein fate, Protein modification and repair, Transport and binding proteins, Other]
Pssm-ID: 130261 [Multi-domain] Cd Length: 708 Bit Score: 95.58 E-value: 1.74e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 2 ITLKNVSKWYGH-FQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVNDkkTDLAKLRSRVG 80
Cdd:TIGR01193 474 IVINDVSYSYGYgSNILSDISLTIKMNSKTTIVGMSGSGKSTLAKLLVGFFQARSGEILLNGFSLKD--IDRHTLRQFIN 551
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 81 MVFQHFELFPHlSIIENLtlaqvkVLKRNKAPAREKALKLLERVGLSAHANKFP-----------AQLSGGQQQRVAIAR 149
Cdd:TIGR01193 552 YLPQEPYIFSG-SILENL------LLGAKENVSQDEIWAACEIAEIKDDIENMPlgyqtelseegSSISGGQKQRIALAR 624
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 150 ALCMDPIAMLFDEPTSALDPEMINEVLDVMVELANEgmTMMVVTHEMGFARKVaNRVIFMDEGKIIEDSPKDAFFDnpks 229
Cdd:TIGR01193 625 ALLTDSKVLILDESTSNLDTITEKKIVNNLLNLQDK--TIIFVAHRLSVAKQS-DKIIVLDHGKIIEQGSHDELLD---- 697
|
250
....*....|..
gi 446554041 230 drAKDFLAKILH 241
Cdd:TIGR01193 698 --RNGFYASLIH 707
|
|
| PRK11174 |
PRK11174 |
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed |
34-216 |
2.01e-22 |
|
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
Pssm-ID: 236870 [Multi-domain] Cd Length: 588 Bit Score: 95.30 E-value: 2.01e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEPVQqGEITVDGIVVNDkkTDLAKLRSRVGMVFQHFELFpHLSIIENLTLAQVKvlkrnkapA 113
Cdd:PRK11174 383 GPSGAGKTSLLNALLGFLPYQ-GSLKINGIELRE--LDPESWRKHLSWVGQNPQLP-HGTLRDNVLLGNPD--------A 450
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 114 REKALK-LLERvglsAHANKFPAQ---------------LSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLD 177
Cdd:PRK11174 451 SDEQLQqALEN----AWVSEFLPLlpqgldtpigdqaagLSVGQAQRLALARALLQPCQLLLLDEPTASLDAHSEQLVMQ 526
|
170 180 190
....*....|....*....|....*....|....*....
gi 446554041 178 VMVELANEGMTMMvVTHEMGFARKVaNRVIFMDEGKIIE 216
Cdd:PRK11174 527 ALNAASRRQTTLM-VTHQLEDLAQW-DQIWVMQDGQIVQ 563
|
|
| rim_protein |
TIGR01257 |
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ... |
34-214 |
2.04e-22 |
|
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]
Pssm-ID: 130324 [Multi-domain] Cd Length: 2272 Bit Score: 95.85 E-value: 2.04e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEPVQQGEITVDGivvNDKKTDLAKLRSRVGMVFQHFELFPHLSIIEN-LTLAQVKvlKRNKAP 112
Cdd:TIGR01257 963 GHNGAGKTTTLSILTGLLPPTSGTVLVGG---KDIETNLDAVRQSLGMCPQHNILFHHLTVAEHiLFYAQLK--GRSWEE 1037
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 113 AREKALKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLDVMVELaNEGMTMMVV 192
Cdd:TIGR01257 1038 AQLEMEAMLEDTGLHHKRNEEAQDLSGGMQRKLSVAIAFVGDAKVVVLDEPTSGVDPYSRRSIWDLLLKY-RSGRTIIMS 1116
|
170 180
....*....|....*....|..
gi 446554041 193 THEMGFARKVANRVIFMDEGKI 214
Cdd:TIGR01257 1117 THHMDEADLLGDRIAIISQGRL 1138
|
|
| galliderm_ABC |
TIGR03740 |
gallidermin-class lantibiotic protection ABC transporter, ATP-binding subunit; Model TIGR03731 ... |
5-215 |
2.85e-22 |
|
gallidermin-class lantibiotic protection ABC transporter, ATP-binding subunit; Model TIGR03731 represents the family of all lantibiotics related to gallidermin, including epidermin, mutatin, and nisin. This protein family describes the ATP-binding subunit of a gallidermin/epidermin class lantibiotic protection transporter. It is largely restricted to gallidermin-family lantibiotic biosynthesis and export cassettes, but also occurs in orphan transporter cassettes in species that lack candidate lantibiotic precursor and synthetase genes.
Pssm-ID: 163452 [Multi-domain] Cd Length: 223 Bit Score: 90.92 E-value: 2.85e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 5 KNVSKWYGHFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVNDKktDLAKlrsrVGMVFQ 84
Cdd:TIGR03740 4 KNLSKRFGKQTAVNNISLTVPKNSVYGLLGPNGAGKSTLLKMITGILRPTSGEIIFDGHPWTRK--DLHK----IGSLIE 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 85 HFELFPHLSIIENLtlaqvKVLKRNKAPAREKALKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMDPIAMLFDEPT 164
Cdd:TIGR03740 78 SPPLYENLTARENL-----KVHTTLLGLPDSRIDEVLNIVDLTNTGKKKAKQFSLGMKQRLGIAIALLNHPKLLILDEPT 152
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 446554041 165 SALDPEMINEVLDVMVELANEGMTMMVVTHEMGFARKVANRVIFMDEGKII 215
Cdd:TIGR03740 153 NGLDPIGIQELRELIRSFPEQGITVILSSHILSEVQQLADHIGIISEGVLG 203
|
|
| PRK10895 |
PRK10895 |
lipopolysaccharide ABC transporter ATP-binding protein; Provisional |
1-225 |
3.10e-22 |
|
lipopolysaccharide ABC transporter ATP-binding protein; Provisional
Pssm-ID: 182817 [Multi-domain] Cd Length: 241 Bit Score: 91.49 E-value: 3.10e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 1 MITL--KNVSKWYGHFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQQGEITVDgivvnDKKTDLAKLRSR 78
Cdd:PRK10895 1 MATLtaKNLAKAYKGRRVVEDVSLTVNSGEIVGLLGPNGAGKTTTFYMVVGIVPRDAGNIIID-----DEDISLLPLHAR 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 79 ----VGMVFQHFELFPHLSIIENLtLAQVKVLKRNKAPARE-KALKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCM 153
Cdd:PRK10895 76 arrgIGYLPQEASIFRRLSVYDNL-MAVLQIRDDLSAEQREdRANELMEEFHIEHLRDSMGQSLSGGERRRVEIARALAA 154
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446554041 154 DPIAMLFDEPTSALDPEMINEVLDVMVELANEGMTMMVVTHEMGFARKVANRVIFMDEGKII-EDSPKDAFFD 225
Cdd:PRK10895 155 NPKFILLDEPFAGVDPISVIDIKRIIEHLRDSGLGVLITDHNVRETLAVCERAYIVSQGHLIaHGTPTEILQD 227
|
|
| LptB |
COG1137 |
ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope ... |
1-228 |
4.39e-22 |
|
ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440752 [Multi-domain] Cd Length: 240 Bit Score: 90.86 E-value: 4.39e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 1 MITLKNVSKWYGHFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVndkkTDLA-KLRSRV 79
Cdd:COG1137 3 TLEAENLVKSYGKRTVVKDVSLEVNQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGRIFLDGEDI----THLPmHKRARL 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 80 GMVF--QHFELFPHLSIIENLtLAQVKVLKRNKAPAREKALKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMDPIA 157
Cdd:COG1137 79 GIGYlpQEASIFRKLTVEDNI-LAVLELRKLSKKEREERLEELLEEFGITHLRKSKAYSLSGGERRRVEIARALATNPKF 157
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446554041 158 MLFDEPTSALDPEMINEVLDVMVELANEGMTMMVVTHEmgfAR---KVANRVIFMDEGKIIEDSPKDAFFDNPK 228
Cdd:COG1137 158 ILLDEPFAGVDPIAVADIQKIIRHLKERGIGVLITDHN---VRetlGICDRAYIISEGKVLAEGTPEEILNNPL 228
|
|
| nikD |
PRK10418 |
nickel transporter ATP-binding protein NikD; Provisional |
34-237 |
1.20e-21 |
|
nickel transporter ATP-binding protein NikD; Provisional
Pssm-ID: 236688 [Multi-domain] Cd Length: 254 Bit Score: 90.14 E-value: 1.20e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEP----VQQGEITVDGIVVNdkktdLAKLRSR-VGMVFQHfelfPHLSIIENLTL---AQVKV 105
Cdd:PRK10418 36 GGSGSGKSLTCAAALGILPagvrQTAGRVLLDGKPVA-----PCALRGRkIATIMQN----PRSAFNPLHTMhthARETC 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 106 LKRNKAPAREKALKLLERVGLSAHA---NKFPAQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLDVMVEL 182
Cdd:PRK10418 107 LALGKPADDATLTAALEAVGLENAArvlKLYPFEMSGGMLQRMMIALALLCEAPFIIADEPTTDLDVVAQARILDLLESI 186
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 446554041 183 ANE-GMTMMVVTHEMGFARKVANRVIFMDEGKIIEDSPKDAFFDNPKSDRAKDFLA 237
Cdd:PRK10418 187 VQKrALGMLLVTHDMGVVARLADDVAVMSHGRIVEQGDVETLFNAPKHAVTRSLVS 242
|
|
| cbiO |
PRK13642 |
energy-coupling factor transporter ATPase; |
34-224 |
3.30e-21 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184202 [Multi-domain] Cd Length: 277 Bit Score: 89.38 E-value: 3.30e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVNDKktDLAKLRSRVGMVFQHfelfPHLSIIENLTLAQVKVLKRNKAPA 113
Cdd:PRK13642 40 GQNGSGKSTTARLIDGLFEEFEGKVKIDGELLTAE--NVWNLRRKIGMVFQN----PDNQFVGATVEDDVAFGMENQGIP 113
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 114 REKALKLLERVGLSAHANKF----PAQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLDVMVELANE-GMT 188
Cdd:PRK13642 114 REEMIKRVDEALLAVNMLDFktrePARLSGGQKQRVAVAGIIALRPEIIILDESTSMLDPTGRQEIMRVIHEIKEKyQLT 193
|
170 180 190
....*....|....*....|....*....|....*.
gi 446554041 189 MMVVTHEMGFARKvANRVIFMDEGKIIEDSPKDAFF 224
Cdd:PRK13642 194 VLSITHDLDEAAS-SDRILVMKAGEIIKEAAPSELF 228
|
|
| ABC_NatA_like |
cd03267 |
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; ... |
34-218 |
3.40e-21 |
|
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled to proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of the single ATP-binding protein and the single integral membrane protein.
Pssm-ID: 213234 [Multi-domain] Cd Length: 236 Bit Score: 88.54 E-value: 3.40e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVNDKKTdlaKLRSRVGMVF-QHFELFPHLSIIENLTLAQvKVLKRNKAP 112
Cdd:cd03267 54 GPNGAGKTTTLKILSGLLQPTSGEVRVAGLVPWKRRK---KFLRRIGVVFgQKTQLWWDLPVIDSFYLLA-AIYDLPPAR 129
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 113 AREKALKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLDVMVELANE-GMTMMV 191
Cdd:cd03267 130 FKKRLDELSELLDLEELLDTPVRQLSLGQRMRAEIAAALLHEPEILFLDEPTIGLDVVAQENIRNFLKEYNRErGTTVLL 209
|
170 180
....*....|....*....|....*..
gi 446554041 192 VTHEMGFARKVANRVIFMDEGKIIEDS 218
Cdd:cd03267 210 TSHYMKDIEALARRVLVIDKGRLLYDG 236
|
|
| ccmA |
TIGR01189 |
heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein ... |
34-197 |
3.64e-21 |
|
heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein encoded by ccmA in bacteria. An exception is, an arabidopsis protein. Quite likely this is encoded by an organelle. Bacterial c-type cytocromes are located on the periplasmic side of the cytoplasmic membrane. Several gene products encoded in a locus designated as 'ccm' are implicated in the transport and assembly of the functional cytochrome C. This cluster includes genes: ccmA;B;C;D;E;F;G and H. The posttranslational pathway includes the transport of heme moiety, the secretion of the apoprotein and the covalent attachment of the heme with the apoprotein. The proteins ccmA and B represent an ABC transporter; ccmC and D participate in heme transfer to ccmE, which function as a periplasmic heme chaperone. The presence of ccmF, G and H is suggested to be obligatory for the final functional assembly of cytochrome c. [Protein fate, Protein and peptide secretion and trafficking, Transport and binding proteins, Other]
Pssm-ID: 273491 [Multi-domain] Cd Length: 198 Bit Score: 87.41 E-value: 3.64e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVNDkktdLAKLRSRVGMVFQHFE-LFPHLSIIENLTLaqvkvLKRNKAP 112
Cdd:TIGR01189 33 GPNGIGKTTLLRILAGLLRPDSGEVRWNGTPLAE----QRDEPHENILYLGHLPgLKPELSALENLHF-----WAAIHGG 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 113 AREKALKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDP---EMINEVLDvmVELANEGMTM 189
Cdd:TIGR01189 104 AQRTIEDALAAVGLTGFEDLPAAQLSAGQQRRLALARLWLSRRPLWILDEPTTALDKagvALLAGLLR--AHLARGGIVL 181
|
....*...
gi 446554041 190 MVVTHEMG 197
Cdd:TIGR01189 182 LTTHQDLG 189
|
|
| ATM1 |
COG5265 |
ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components ... |
34-216 |
6.13e-21 |
|
ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444078 [Multi-domain] Cd Length: 605 Bit Score: 91.03 E-value: 6.13e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVNDkkTDLAKLRSRVGMVFQHFELFphlsiieNLTLAQvkvlkrNKAPA 113
Cdd:COG5265 391 GPSGAGKSTLARLLFRFYDVTSGRILIDGQDIRD--VTQASLRAAIGIVPQDTVLF-------NDTIAY------NIAYG 455
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 114 R--------EKALKLlervglsAHANKFPAQ---------------LSGGQQQRVAIARALCMDPIAMLFDEPTSALDPE 170
Cdd:COG5265 456 RpdaseeevEAAARA-------AQIHDFIESlpdgydtrvgerglkLSGGEKQRVAIARTLLKNPPILIFDEATSALDSR 528
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 446554041 171 MINEVLDVMVELAnEGMTMMVVTHemgfaR--KV--ANRVIFMDEGKIIE 216
Cdd:COG5265 529 TERAIQAALREVA-RGRTTLVIAH-----RlsTIvdADEILVLEAGRIVE 572
|
|
| araG |
PRK11288 |
L-arabinose ABC transporter ATP-binding protein AraG; |
34-196 |
6.39e-21 |
|
L-arabinose ABC transporter ATP-binding protein AraG;
Pssm-ID: 183077 [Multi-domain] Cd Length: 501 Bit Score: 90.74 E-value: 6.39e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVNDKKTdLAKLRSRVGMVFQHFELFPHLSIIENLTLAQVK----VLkrN 109
Cdd:PRK11288 37 GENGAGKSTLLKILSGNYQPDAGSILIDGQEMRFAST-TAALAAGVAIIYQELHLVPEMTVAENLYLGQLPhkggIV--N 113
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 110 KAPAREKALKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLDVMVELANEGMTM 189
Cdd:PRK11288 114 RRLLNYEAREQLEHLGVDIDPDTPLKYLSIGQRQMVEIAKALARNARVIAFDEPTSSLSAREIEQLFRVIRELRAEGRVI 193
|
....*..
gi 446554041 190 MVVTHEM 196
Cdd:PRK11288 194 LYVSHRM 200
|
|
| Uup |
COG0488 |
ATPase components of ABC transporters with duplicated ATPase domains [General function ... |
34-215 |
8.90e-21 |
|
ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];
Pssm-ID: 440254 [Multi-domain] Cd Length: 520 Bit Score: 90.51 E-value: 8.90e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEPVQQGEITVDGivvndkktdlaklRSRVGMVFQHFELFPHLSIIENLT--LAQVKVLKRNKA 111
Cdd:COG0488 31 GRNGAGKSTLLKILAGELEPDSGEVSIPK-------------GLRIGYLPQEPPLDDDLTVLDTVLdgDAELRALEAELE 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 112 PAREK-----------------------------ALKLLERVGLS-AHANKFPAQLSGGQQQRVAIARALCMDPIAMLFD 161
Cdd:COG0488 98 ELEAKlaepdedlerlaelqeefealggweaearAEEILSGLGFPeEDLDRPVSELSGGWRRRVALARALLSEPDLLLLD 177
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 446554041 162 EPTSALDPEMInEVLdvmvE--LANEGMTMMVVTHEMGFARKVANRVIFMDEGKII 215
Cdd:COG0488 178 EPTNHLDLESI-EWL----EefLKNYPGTVLVVSHDRYFLDRVATRILELDRGKLT 228
|
|
| ABCC_MRP_domain2 |
cd03244 |
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C ... |
33-219 |
1.84e-20 |
|
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resistance lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213211 [Multi-domain] Cd Length: 221 Bit Score: 86.01 E-value: 1.84e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 33 CGPSGSGKSTLIKTVNGLEPVQQGEITVDGIvvNDKKTDLAKLRSRVGMVFQHFELFPHlSIIENLtlaqvkvlkrnkAP 112
Cdd:cd03244 36 VGRTGSGKSSLLLALFRLVELSSGSILIDGV--DISKIGLHDLRSRISIIPQDPVLFSG-TIRSNL------------DP 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 113 ----AREKALKLLERVGLSAHANKFP-----------AQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPE---MINE 174
Cdd:cd03244 101 fgeySDEELWQALERVGLKEFVESLPggldtvveeggENLSVGQRQLLCLARALLRKSKILVLDEATASVDPEtdaLIQK 180
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 446554041 175 VLdvMVELANegMTMMVVTHE----MGFarkvaNRVIFMDEGKIIE-DSP 219
Cdd:cd03244 181 TI--REAFKD--CTVLTIAHRldtiIDS-----DRILVLDKGRVVEfDSP 221
|
|
| ABC2_perm_RbbA |
NF033858 |
ribosome-associated ATPase/putative transporter RbbA; |
34-219 |
4.00e-20 |
|
ribosome-associated ATPase/putative transporter RbbA;
Pssm-ID: 468210 [Multi-domain] Cd Length: 907 Bit Score: 88.64 E-value: 4.00e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVNDKktDLAkLRSRVGMVFQHFELFPHLSIIENLTL-AQVKVLKRNKAP 112
Cdd:NF033858 299 GSNGCGKSTTMKMLTGLLPASEGEAWLFGQPVDAG--DIA-TRRRVGYMSQAFSLYGELTVRQNLELhARLFHLPAAEIA 375
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 113 AREKALklLERVGLSAHANKFPAQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLDVMVELA-NEGMTMMV 191
Cdd:NF033858 376 ARVAEM--LERFDLADVADALPDSLPLGIRQRLSLAVAVIHKPELLILDEPTSGVDPVARDMFWRLLIELSrEDGVTIFI 453
|
170 180
....*....|....*....|....*....
gi 446554041 192 VTHEMGFARKvANRVIFMDEGKIIE-DSP 219
Cdd:NF033858 454 STHFMNEAER-CDRISLMHAGRVLAsDTP 481
|
|
| 3a01208 |
TIGR00958 |
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other] |
34-227 |
4.21e-20 |
|
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273363 [Multi-domain] Cd Length: 711 Bit Score: 88.63 E-value: 4.21e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVndKKTDLAKLRSRVGMVFQHFELFPHlSIIENLTLAQvkvlkrNKAPA 113
Cdd:TIGR00958 514 GPSGSGKSTVAALLQNLYQPTGGQVLLDGVPL--VQYDHHYLHRQVALVGQEPVLFSG-SVRENIAYGL------TDTPD 584
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 114 REkalklLERVGLSAHANKF---------------PAQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEmINEVLDV 178
Cdd:TIGR00958 585 EE-----IMAAAKAANAHDFimefpngydtevgekGSQLSGGQKQRIAIARALVRKPRVLILDEATSALDAE-CEQLLQE 658
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 446554041 179 MVELAneGMTMMVVTHEMGFARKvANRVIFMDEGKIIEDSPKDAFFDNP 227
Cdd:TIGR00958 659 SRSRA--SRTVLLIAHRLSTVER-ADQILVLKKGSVVEMGTHKQLMEDQ 704
|
|
| type_I_sec_PrtD |
TIGR01842 |
type I secretion system ABC transporter, PrtD family; Type I protein secretion is a system in ... |
34-214 |
5.71e-20 |
|
type I secretion system ABC transporter, PrtD family; Type I protein secretion is a system in some Gram-negative bacteria to export proteins (often proteases) across both inner and outer membranes to the extracellular medium. This is one of three proteins of the type I secretion apparatus. Targeted proteins are not cleaved at the N-terminus, but rather carry signals located toward the extreme C-terminus to direct type I secretion. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 200134 [Multi-domain] Cd Length: 544 Bit Score: 88.17 E-value: 5.71e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVNdkKTDLAKLRSRVGMVFQHFELFPHlsiienlTLAQvkvlkrNKAPA 113
Cdd:TIGR01842 351 GPSGSGKSTLARLIVGIWPPTSGSVRLDGADLK--QWDRETFGKHIGYLPQDVELFPG-------TVAE------NIARF 415
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 114 REKA--LKLLERVGLS-AHA--NKFP-----------AQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLD 177
Cdd:TIGR01842 416 GENAdpEKIIEAAKLAgVHEliLRLPdgydtvigpggATLSGGQRQRIALARALYGDPKLVVLDEPNSNLDEEGEQALAN 495
|
170 180 190
....*....|....*....|....*....|....*..
gi 446554041 178 VMVELANEGMTMMVVTHEMGfARKVANRVIFMDEGKI 214
Cdd:TIGR01842 496 AIKALKARGITVVVITHRPS-LLGCVDKILVLQDGRI 531
|
|
| cbiO |
PRK13638 |
energy-coupling factor ABC transporter ATP-binding protein; |
34-232 |
8.10e-20 |
|
energy-coupling factor ABC transporter ATP-binding protein;
Pssm-ID: 184198 [Multi-domain] Cd Length: 271 Bit Score: 85.44 E-value: 8.10e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVNDKKTDLAKLRSRVGMVFQHfelfPHLSI------------IENLTLA 101
Cdd:PRK13638 34 GANGCGKSTLFMNLSGLLRPQKGAVLWQGKPLDYSKRGLLALRQQVATVFQD----PEQQIfytdidsdiafsLRNLGVP 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 102 QVKVLKRnkapaREKALKLLErvglSAHANKFPAQ-LSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLDVMV 180
Cdd:PRK13638 110 EAEITRR-----VDEALTLVD----AQHFRHQPIQcLSHGQKKRVAIAGALVLQARYLLLDEPTAGLDPAGRTQMIAIIR 180
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 446554041 181 ELANEGMTMMVVTHEMGFARKVANRVIFMDEGKII-EDSPKDAFFDNPKSDRA 232
Cdd:PRK13638 181 RIVAQGNHVIISSHDIDLIYEISDAVYVLRQGQILtHGAPGEVFACTEAMEQA 233
|
|
| COG4586 |
COG4586 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
34-226 |
1.44e-19 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 443643 [Multi-domain] Cd Length: 323 Bit Score: 85.52 E-value: 1.44e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNG-LEPvQQGEITVDGIVVNDKKTDLAKlrsRVGMVF-QHFELFPHLSIIENLTLaqvkvlkrNKA 111
Cdd:COG4586 55 GPNGAGKSTTIKMLTGiLVP-TSGEVRVLGYVPFKRRKEFAR---RIGVVFgQRSQLWWDLPAIDSFRL--------LKA 122
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 112 ----PARE--KALKLL-ERVGLSAHANKFPAQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLDVMVEL-A 183
Cdd:COG4586 123 iyriPDAEykKRLDELvELLDLGELLDTPVRQLSLGQRMRCELAAALLHRPKILFLDEPTIGLDVVSKEAIREFLKEYnR 202
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 446554041 184 NEGMTMMVVTHEMGFARKVANRVIFMDEGKIIEDSPKDAFFDN 226
Cdd:COG4586 203 ERGTTILLTSHDMDDIEALCDRVIVIDHGRIIYDGSLEELKER 245
|
|
| PLN03211 |
PLN03211 |
ABC transporter G-25; Provisional |
34-195 |
2.76e-19 |
|
ABC transporter G-25; Provisional
Pssm-ID: 215634 [Multi-domain] Cd Length: 659 Bit Score: 86.47 E-value: 2.76e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLepvQQGEITVDGIVVNDKKTDLAKLRsRVGMVFQHFELFPHLSIIEnlTLAQVKVLKRNKAPA 113
Cdd:PLN03211 101 GPSGSGKSTLLNALAGR---IQGNNFTGTILANNRKPTKQILK-RTGFVTQDDILYPHLTVRE--TLVFCSLLRLPKSLT 174
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 114 REKALKLLERV----GLSAH-----ANKFPAQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLDVMVELAN 184
Cdd:PLN03211 175 KQEKILVAESViselGLTKCentiiGNSFIRGISGGERKRVSIAHEMLINPSLLILDEPTSGLDATAAYRLVLTLGSLAQ 254
|
170
....*....|.
gi 446554041 185 EGMTMMVVTHE 195
Cdd:PLN03211 255 KGKTIVTSMHQ 265
|
|
| oppD |
PRK09473 |
oligopeptide transporter ATP-binding component; Provisional |
34-224 |
3.35e-19 |
|
oligopeptide transporter ATP-binding component; Provisional
Pssm-ID: 181888 [Multi-domain] Cd Length: 330 Bit Score: 84.78 E-value: 3.35e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGL---EPVQQGEITVDGI-VVNDKKTDLAKLRS-RVGMVFQH--FELFPHLSIIENLTlaQVKVL 106
Cdd:PRK09473 49 GESGSGKSQTAFALMGLlaaNGRIGGSATFNGReILNLPEKELNKLRAeQISMIFQDpmTSLNPYMRVGEQLM--EVLML 126
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 107 KR--NKAPAREKALKLLERVGLSaHANK----FPAQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLDVMV 180
Cdd:PRK09473 127 HKgmSKAEAFEESVRMLDAVKMP-EARKrmkmYPHEFSGGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLN 205
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 446554041 181 ELANE-GMTMMVVTHEMGFARKVANRVIFMDEGKIIE-DSPKDAFF 224
Cdd:PRK09473 206 ELKREfNTAIIMITHDLGVVAGICDKVLVMYAGRTMEyGNARDVFY 251
|
|
| PRK10247 |
PRK10247 |
putative ABC transporter ATP-binding protein YbbL; Provisional |
34-195 |
4.31e-19 |
|
putative ABC transporter ATP-binding protein YbbL; Provisional
Pssm-ID: 182331 [Multi-domain] Cd Length: 225 Bit Score: 82.45 E-value: 4.31e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEPVQQGEITVDGivvndkkTDLAKL-----RSRVGMVFQHFELFPHlSIIENLTLA-QVkvlk 107
Cdd:PRK10247 40 GPSGCGKSTLLKIVASLISPTSGTLLFEG-------EDISTLkpeiyRQQVSYCAQTPTLFGD-TVYDNLIFPwQI---- 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 108 RNKAPAREKALKLLERVGLSAHA-NKFPAQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLDVMVELANE- 185
Cdd:PRK10247 108 RNQQPDPAIFLDDLERFALPDTIlTKNIAELSGGEKQRISLIRNLQFMPKVLLLDEITSALDESNKHNVNEIIHRYVREq 187
|
170
....*....|
gi 446554041 186 GMTMMVVTHE 195
Cdd:PRK10247 188 NIAVLWVTHD 197
|
|
| YddA |
COG4178 |
ABC-type uncharacterized transport system, permease and ATPase components [General function ... |
34-194 |
5.52e-19 |
|
ABC-type uncharacterized transport system, permease and ATPase components [General function prediction only];
Pssm-ID: 443337 [Multi-domain] Cd Length: 571 Bit Score: 85.24 E-value: 5.52e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEPVQQGEITvdgivvndkktdlakLRSRVGMVF--QHfelfPHLSIIenlTLAQVkVL--KRN 109
Cdd:COG4178 396 GPSGSGKSTLLRAIAGLWPYGSGRIA---------------RPAGARVLFlpQR----PYLPLG---TLREA-LLypATA 452
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 110 KAPAREKALKLLERVGLSAHANKF------PAQLSGGQQQRVAIARALCMDPiAMLF-DEPTSALDPEMINEVLDVMVEl 182
Cdd:COG4178 453 EAFSDAELREALEAVGLGHLAERLdeeadwDQVLSLGEQQRLAFARLLLHKP-DWLFlDEATSALDEENEAALYQLLRE- 530
|
170
....*....|..
gi 446554041 183 ANEGMTMMVVTH 194
Cdd:COG4178 531 ELPGTTVISVGH 542
|
|
| PRK10253 |
PRK10253 |
iron-enterobactin ABC transporter ATP-binding protein; |
11-221 |
7.45e-19 |
|
iron-enterobactin ABC transporter ATP-binding protein;
Pssm-ID: 182336 [Multi-domain] Cd Length: 265 Bit Score: 82.73 E-value: 7.45e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 11 YGHFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVNDKKTDlaKLRSRVGMVFQHFELFP 90
Cdd:PRK10253 17 YGKYTVAENLTVEIPDGHFTAIIGPNGCGKSTLLRTLSRLMTPAHGHVWLDGEHIQHYASK--EVARRIGLLAQNATTPG 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 91 HLSIIENLTLAQVK---VLKRNKAPAREKALKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMDPIAMLFDEPTSAL 167
Cdd:PRK10253 95 DITVQELVARGRYPhqpLFTRWRKEDEEAVTKAMQATGITHLADQSVDTLSGGQRQRAWIAMVLAQETAIMLLDEPTTWL 174
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 446554041 168 DPEMINEVLDVMVELANE-GMTMMVVTHEMGFARKVANRVIFMDEGKII-EDSPKD 221
Cdd:PRK10253 175 DISHQIDLLELLSELNREkGYTLAAVLHDLNQACRYASHLIALREGKIVaQGAPKE 230
|
|
| ABC_FeS_Assembly |
cd03217 |
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of ... |
34-221 |
8.58e-19 |
|
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of iron-sulfur clusters (Fe-S) depends on multi-protein systems. The SUF system of E. coli and Erwinia chrysanthemi is important for Fe-S biogenesis under stressful conditions. The SUF system is made of six proteins: SufC is an atypical cytoplasmic ABC-ATPase, which forms a complex with SufB and SufD; SufA plays the role of a scaffold protein for assembly of iron-sulfur clusters and delivery to target proteins; SufS is a cysteine desulfurase which mobilizes the sulfur atom from cysteine and provides it to the cluster; SufE has no associated function yet.
Pssm-ID: 213184 [Multi-domain] Cd Length: 200 Bit Score: 81.03 E-value: 8.58e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLE--PVQQGEITVDGIVVNDKKTDlakLRSRVG--MVFQHFELFPHLSIIEnltlaqvkvlkrn 109
Cdd:cd03217 33 GPNGSGKSTLAKTIMGHPkyEVTEGEILFKGEDITDLPPE---ERARLGifLAFQYPPEIPGVKNAD------------- 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 110 kaparekalkLLERVGLSahankfpaqLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLDVMVELANEGMTM 189
Cdd:cd03217 97 ----------FLRYVNEG---------FSGGEKKRNEILQLLLLEPDLAILDEPDSGLDIDALRLVAEVINKLREEGKSV 157
|
170 180 190
....*....|....*....|....*....|...
gi 446554041 190 MVVTH-EMGFARKVANRVIFMDEGKIIEDSPKD 221
Cdd:cd03217 158 LIITHyQRLLDYIKPDRVHVLYDGRIVKSGDKE 190
|
|
| PRK10261 |
PRK10261 |
glutathione transporter ATP-binding protein; Provisional |
34-239 |
1.37e-18 |
|
glutathione transporter ATP-binding protein; Provisional
Pssm-ID: 182342 [Multi-domain] Cd Length: 623 Bit Score: 84.14 E-value: 1.37e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVNDKKTDLAKLRSR------------VGMVFQH--FELFPHLSIIENLT 99
Cdd:PRK10261 49 GESGSGKSVTALALMRLLEQAGGLVQCDKMLLRRRSRQVIELSEQsaaqmrhvrgadMAMIFQEpmTSLNPVFTVGEQIA 128
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 100 laqvKVLKRNKAPAREKAL----KLLERVGL-SAHA--NKFPAQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMI 172
Cdd:PRK10261 129 ----ESIRLHQGASREEAMveakRMLDQVRIpEAQTilSRYPHQLSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQ 204
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446554041 173 NEVLDVMVELANE-GMTMMVVTHEMGFARKVANRVIFMDEGKIIEDSPKDAFFDNPKSDRAKDFLAKI 239
Cdd:PRK10261 205 AQILQLIKVLQKEmSMGVIFITHDMGVVAEIADRVLVMYQGEAVETGSVEQIFHAPQHPYTRALLAAV 272
|
|
| PRK13539 |
PRK13539 |
cytochrome c biogenesis protein CcmA; Provisional |
34-194 |
1.37e-18 |
|
cytochrome c biogenesis protein CcmA; Provisional
Pssm-ID: 237421 [Multi-domain] Cd Length: 207 Bit Score: 80.69 E-value: 1.37e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEPVQQGEITVDGivvndKKTDLAKLRSRVGMVFQHFELFPHLSIIENLTLAQvkvlkRNKAPA 113
Cdd:PRK13539 35 GPNGSGKTTLLRLIAGLLPPAAGTIKLDG-----GDIDDPDVAEACHYLGHRNAMKPALTVAENLEFWA-----AFLGGE 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 114 REKALKLLERVGLSAHANkFPAQ-LSGGQQQRVAIARALCMD-PIAMLfDEPTSALDPEMINEVLDVMVELANEGMTMMV 191
Cdd:PRK13539 105 ELDIAAALEAVGLAPLAH-LPFGyLSAGQKRRVALARLLVSNrPIWIL-DEPTAALDAAAVALFAELIRAHLAQGGIVIA 182
|
...
gi 446554041 192 VTH 194
Cdd:PRK13539 183 ATH 185
|
|
| xylG |
TIGR02633 |
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ... |
1-219 |
3.10e-18 |
|
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]
Pssm-ID: 131681 [Multi-domain] Cd Length: 500 Bit Score: 82.95 E-value: 3.10e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 1 MITLKNVSKWYGHFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEP--VQQGEITVDG---IVVNDKKTDlakl 75
Cdd:TIGR02633 1 LLEMKGIVKTFGGVKALDGIDLEVRPGECVGLCGENGAGKSTLMKILSGVYPhgTWDGEIYWSGsplKASNIRDTE---- 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 76 RSRVGMVFQHFELFPHLSIIENLTLAQVKVLK---RNKAPAREKALKLLERVGLSAHANKFP-AQLSGGQQQRVAIARAL 151
Cdd:TIGR02633 77 RAGIVIIHQELTLVPELSVAENIFLGNEITLPggrMAYNAMYLRAKNLLRELQLDADNVTRPvGDYGGGQQQLVEIAKAL 156
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446554041 152 CMDPIAMLFDEPTSALDPEMINEVLDVMVELANEGMTMMVVTHEMGFARKVANRVIFMDEGKIIEDSP 219
Cdd:TIGR02633 157 NKQARLLILDEPSSSLTEKETEILLDIIRDLKAHGVACVYISHKLNEVKAVCDTICVIRDGQHVATKD 224
|
|
| PRK13549 |
PRK13549 |
xylose transporter ATP-binding subunit; Provisional |
33-223 |
5.73e-18 |
|
xylose transporter ATP-binding subunit; Provisional
Pssm-ID: 184134 [Multi-domain] Cd Length: 506 Bit Score: 82.28 E-value: 5.73e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 33 CGPSGSGKSTLIKTVNGLEPV--QQGEITVDGIVV---NDKKTDlaklrsRVGMVFQHFEL--FPHLSIIENLTLA---- 101
Cdd:PRK13549 37 CGENGAGKSTLMKVLSGVYPHgtYEGEIIFEGEELqasNIRDTE------RAGIAIIHQELalVKELSVLENIFLGneit 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 102 QVKVLKRNKAPARekALKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLDVMVE 181
Cdd:PRK13549 111 PGGIMDYDAMYLR--AQKLLAQLKLDINPATPVGNLGLGQQQLVEIAKALNKQARLLILDEPTASLTESETAVLLDIIRD 188
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 446554041 182 LANEGMTMMVVTHEMGFARKVANRVIFMDEGKIIEDSPKDAF 223
Cdd:PRK13549 189 LKAHGIACIYISHKLNEVKAISDTICVIRDGRHIGTRPAAGM 230
|
|
| ABCF_EF-3 |
cd03221 |
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is ... |
2-213 |
9.14e-18 |
|
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is a cytosolic protein required by fungal ribosomes for in vitro protein synthesis and for in vivo growth. EF-3 stimulates the binding of the EF-1: GTP: aa-tRNA ternary complex to the ribosomal A site by facilitated release of the deacylated tRNA from the E site. The reaction requires ATP hydrolysis. EF-3 contains two ATP nucleotide binding sequence (NBS) motifs. NBSI is sufficient for the intrinsic ATPase activity. NBSII is essential for the ribosome-stimulated functions.
Pssm-ID: 213188 [Multi-domain] Cd Length: 144 Bit Score: 77.10 E-value: 9.14e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 2 ITLKNVSKWYGHFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQQGEITVDGivvndkktdlaklrsrvGM 81
Cdd:cd03221 1 IELENLSKTYGGKLLLKDISLTINPGDRIGLVGRNGAGKSTLLKLIAGELEPDEGIVTWGS-----------------TV 63
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 82 VFQHFElfphlsiienltlaqvkvlkrnkaparekalkllervglsahankfpaQLSGGQQQRVAIARALCMDPIAMLFD 161
Cdd:cd03221 64 KIGYFE------------------------------------------------QLSGGEKMRLALAKLLLENPNLLLLD 95
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 446554041 162 EPTSALDPEMINEVLDVMVELanEGmTMMVVTHEMGFARKVANRVIFMDEGK 213
Cdd:cd03221 96 EPTNHLDLESIEALEEALKEY--PG-TVILVSHDRYFLDQVATKIIELEDGK 144
|
|
| PRK09700 |
PRK09700 |
D-allose ABC transporter ATP-binding protein AlsA; |
34-216 |
1.31e-17 |
|
D-allose ABC transporter ATP-binding protein AlsA;
Pssm-ID: 182036 [Multi-domain] Cd Length: 510 Bit Score: 81.37 E-value: 1.31e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVNdKKTDLAKLRSRVGMVFQHFE---LFPHLSIIENLTLAQVKVLKRNK 110
Cdd:PRK09700 296 GLVGSGRTELMNCLFGVDKRAGGEIRLNGKDIS-PRSPLDAVKKGMAYITESRRdngFFPNFSIAQNMAISRSLKDGGYK 374
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 111 A------PAREKALKLLERVGLS---AHANKFPAQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLDVMVE 181
Cdd:PRK09700 375 GamglfhEVDEQRTAENQRELLAlkcHSVNQNITELSGGNQQKVLISKWLCCCPEVIIFDEPTRGIDVGAKAEIYKVMRQ 454
|
170 180 190
....*....|....*....|....*....|....*
gi 446554041 182 LANEGMTMMVVTHEMGFARKVANRVIFMDEGKIIE 216
Cdd:PRK09700 455 LADDGKVILMVSSELPEIITVCDRIAVFCEGRLTQ 489
|
|
| PvdE |
COG4615 |
ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion ... |
37-219 |
1.79e-17 |
|
ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion transport and metabolism];
Pssm-ID: 443659 [Multi-domain] Cd Length: 547 Bit Score: 81.00 E-value: 1.79e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 37 GSGKSTLIKTVNGLEPVQQGEITVDGIVVNDkkTDLAKLRSRVGMVFQHFELFPHLsiienltlaqvkvLKRNKAPAREK 116
Cdd:COG4615 368 GSGKSTLAKLLTGLYRPESGEILLDGQPVTA--DNREAYRQLFSAVFSDFHLFDRL-------------LGLDGEADPAR 432
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 117 ALKLLERVGLsAH-----ANKF-PAQLSGGQQQRVAIARALCMD-PIaMLFDEPTSALDPE----MINEVLdvmVELANE 185
Cdd:COG4615 433 ARELLERLEL-DHkvsveDGRFsTTDLSQGQRKRLALLVALLEDrPI-LVFDEWAADQDPEfrrvFYTELL---PELKAR 507
|
170 180 190
....*....|....*....|....*....|....*
gi 446554041 186 GMTMMVVTH-EMGFArkVANRVIFMDEGKIIEDSP 219
Cdd:COG4615 508 GKTVIAISHdDRYFD--LADRVLKMDYGKLVELTG 540
|
|
| 40850658_otr |
NF000106 |
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit; |
96-221 |
2.69e-17 |
|
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;
Pssm-ID: 411078 [Multi-domain] Cd Length: 351 Bit Score: 79.78 E-value: 2.69e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 96 ENLTLAQvKVLKRNKAPAREKALKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEV 175
Cdd:NF000106 105 ENLYMIG-R*LDLSRKDARARADELLERFSLTEAAGRAAAKYSGGMRRRLDLAASMIGRPAVLYLDEPTTGLDPRTRNEV 183
|
90 100 110 120
....*....|....*....|....*....|....*....|....*.
gi 446554041 176 LDVMVELANEGMTMMVVTHEMGFARKVANRVIFMDEGKIIEDSPKD 221
Cdd:NF000106 184 WDEVRSMVRDGATVLLTTQYMEEAEQLAHELTVIDRGRVIADGKVD 229
|
|
| znuC |
PRK09544 |
high-affinity zinc transporter ATPase; Reviewed |
1-196 |
3.17e-17 |
|
high-affinity zinc transporter ATPase; Reviewed
Pssm-ID: 181939 [Multi-domain] Cd Length: 251 Bit Score: 78.23 E-value: 3.17e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 1 MITLKNVSKWYGHFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQQGEITVDGivvndkktdlaklRSRVG 80
Cdd:PRK09544 4 LVSLENVSVSFGQRRVLSDVSLELKPGKILTLLGPNGAGKSTLVRVVLGLVAPDEGVIKRNG-------------KLRIG 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 81 MVFQHFELFPHLSiienLTLAQVKVLKrnkaPAREKA--LKLLERVGlSAHANKFPAQ-LSGGQQQRVAIARALCMDPIA 157
Cdd:PRK09544 71 YVPQKLYLDTTLP----LTVNRFLRLR----PGTKKEdiLPALKRVQ-AGHLIDAPMQkLSGGETQRVLLARALLNRPQL 141
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 446554041 158 MLFDEPTSALDPEMINEVLDVMVELANE-GMTMMVVTHEM 196
Cdd:PRK09544 142 LVLDEPTQGVDVNGQVALYDLIDQLRRElDCAVLMVSHDL 181
|
|
| PRK15093 |
PRK15093 |
peptide ABC transporter ATP-binding protein SapD; |
34-227 |
3.95e-17 |
|
peptide ABC transporter ATP-binding protein SapD;
Pssm-ID: 185049 [Multi-domain] Cd Length: 330 Bit Score: 79.08 E-value: 3.95e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEPvQQGEITVDGIVVNDkkTDLAKLRSR---------VGMVFQHFE--LFPHLSIIENLTLA- 101
Cdd:PRK15093 40 GESGSGKSLIAKAICGVTK-DNWRVTADRMRFDD--IDLLRLSPRerrklvghnVSMIFQEPQscLDPSERVGRQLMQNi 116
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 102 -----QVKVLKRNKAPAReKALKLLERVGLSAHAN---KFPAQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMIN 173
Cdd:PRK15093 117 pgwtyKGRWWQRFGWRKR-RAIELLHRVGIKDHKDamrSFPYELTEGECQKVMIAIALANQPRLLIADEPTNAMEPTTQA 195
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 446554041 174 EVLDVMVEL-ANEGMTMMVVTHEMGFARKVANRVIFMDEGKIIEDSPKDAFFDNP 227
Cdd:PRK15093 196 QIFRLLTRLnQNNNTTILLISHDLQMLSQWADKINVLYCGQTVETAPSKELVTTP 250
|
|
| PRK15439 |
PRK15439 |
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional |
1-222 |
1.20e-16 |
|
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
Pssm-ID: 185336 [Multi-domain] Cd Length: 510 Bit Score: 78.55 E-value: 1.20e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 1 MITLKNVSKWYGHFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVNDKKTDLAKlrsRVG 80
Cdd:PRK15439 11 LLCARSISKQYSGVEVLKGIDFTLHAGEVHALLGGNGAGKSTLMKIIAGIVPPDSGTLEIGGNPCARLTPAKAH---QLG 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 81 --MVFQHFELFPHLSIIENLTLaqvKVLKRNKAPAREKALKLLERVGLSAHANKfpAQLSGGQQQRVAIARALCMDPIAM 158
Cdd:PRK15439 88 iyLVPQEPLLFPNLSVKENILF---GLPKRQASMQKMKQLLAALGCQLDLDSSA--GSLEVADRQIVEILRGLMRDSRIL 162
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446554041 159 LFDEPTSALDPEMINEVLDVMVELANEGMTMMVVTHEMGFARKVANRVIFMDEGKI-----IEDSPKDA 222
Cdd:PRK15439 163 ILDEPTASLTPAETERLFSRIRELLAQGVGIVFISHKLPEIRQLADRISVMRDGTIalsgkTADLSTDD 231
|
|
| ABCC_MRP_domain1 |
cd03250 |
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This ... |
33-213 |
2.02e-16 |
|
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This subfamily is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213217 [Multi-domain] Cd Length: 204 Bit Score: 74.81 E-value: 2.02e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 33 CGPSGSGKSTLIKTVNGLEPVQQGEITVDGivvndkktdlaklrsRVGMVFQhfelFPHL---SIIENLTLAQV------ 103
Cdd:cd03250 37 VGPVGSGKSSLLSALLGELEKLSGSVSVPG---------------SIAYVSQ----EPWIqngTIRENILFGKPfdeery 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 104 -KVLKrnkAPAREKALKLL---------ERvGLSahankfpaqLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMIN 173
Cdd:cd03250 98 eKVIK---ACALEPDLEILpdgdlteigEK-GIN---------LSGGQKQRISLARAVYSDADIYLLDDPLSAVDAHVGR 164
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 446554041 174 EVLD--VMVELANeGMTMMVVTHEMGFARKvANRVIFMDEGK 213
Cdd:cd03250 165 HIFEncILGLLLN-NKTRILVTHQLQLLPH-ADQIVVLDNGR 204
|
|
| SapD |
COG4170 |
ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms]; |
34-227 |
2.59e-16 |
|
ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms];
Pssm-ID: 443330 [Multi-domain] Cd Length: 331 Bit Score: 76.48 E-value: 2.59e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEPvQQGEITVDGIVVNDKktDLAKLRSR---------VGMVFQHFE--LFPHLSI----IENL 98
Cdd:COG4170 40 GESGSGKSLIAKAICGITK-DNWHVTADRFRWNGI--DLLKLSPRerrkiigreIAMIFQEPSscLDPSAKIgdqlIEAI 116
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 99 TLAQVKVLKRNKAPAREK-ALKLLERVGLSAHA---NKFPAQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINE 174
Cdd:COG4170 117 PSWTFKGKWWQRFKWRKKrAIELLHRVGIKDHKdimNSYPHELTEGECQKVMIAMAIANQPRLLIADEPTNAMESTTQAQ 196
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 446554041 175 VLDVMVELA-NEGMTMMVVTHEMGFARKVANRVIFMDEGKIIEDSPKDAFFDNP 227
Cdd:COG4170 197 IFRLLARLNqLQGTSILLISHDLESISQWADTITVLYCGQTVESGPTEQILKSP 250
|
|
| xylG |
TIGR02633 |
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ... |
34-217 |
3.18e-16 |
|
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]
Pssm-ID: 131681 [Multi-domain] Cd Length: 500 Bit Score: 77.17 E-value: 3.18e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEPVQ-QGEITVDGIVVnDKKTDLAKLRSRVGMVFQHFE---LFPHLSIIENLTLAQVK---VL 106
Cdd:TIGR02633 293 GLVGAGRTELVQALFGAYPGKfEGNVFINGKPV-DIRNPAQAIRAGIAMVPEDRKrhgIVPILGVGKNITLSVLKsfcFK 371
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 107 KRNKAPAREKAL-KLLERVGLSAHANKFP-AQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLDVMVELAN 184
Cdd:TIGR02633 372 MRIDAAAELQIIgSAIQRLKVKTASPFLPiGRLSGGNQQKAVLAKMLLTNPRVLILDEPTRGVDVGAKYEIYKLINQLAQ 451
|
170 180 190
....*....|....*....|....*....|...
gi 446554041 185 EGMTMMVVTHEMGFARKVANRVIFMDEGKIIED 217
Cdd:TIGR02633 452 EGVAIIVVSSELAEVLGLSDRVLVIGEGKLKGD 484
|
|
| ABC_CcmA_heme_exporter |
cd03231 |
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the ... |
34-206 |
3.66e-16 |
|
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the bacterial CcmAB transporter. The CCM family is involved in bacterial cytochrome c biogenesis. Cytochrome c maturation in E. coli requires the ccm operon, which encodes eight membrane proteins (CcmABCDEFGH). CcmE is a periplasmic heme chaperon that binds heme covalently and transfers it onto apocytochrome c in the presence of CcmF, CcmG, and CcmH. The CcmAB proteins represent an ABC transporter and the CcmCD proteins participate in heme transfer to CcmE.
Pssm-ID: 213198 [Multi-domain] Cd Length: 201 Bit Score: 74.07 E-value: 3.66e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVNDKKTDLAKLRSRVGmvfqHFE-LFPHLSIIENLTLAQvkvlkrnKAP 112
Cdd:cd03231 33 GPNGSGKTTLLRILAGLSPPLAGRVLLNGGPLDFQRDSIARGLLYLG----HAPgIKTTLSVLENLRFWH-------ADH 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 113 AREKALKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLDVMV-ELANEGMTMMV 191
Cdd:cd03231 102 SDEQVEEALARVGLNGFEDRPVAQLSAGQQRRVALARLLLSGRPLWILDEPTTALDKAGVARFAEAMAgHCARGGMVVLT 181
|
170
....*....|....*
gi 446554041 192 VTHEMGFARKVANRV 206
Cdd:cd03231 182 THQDLGLSEAGAREL 196
|
|
| NupO |
COG3845 |
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ... |
36-215 |
3.96e-16 |
|
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];
Pssm-ID: 443055 [Multi-domain] Cd Length: 504 Bit Score: 76.99 E-value: 3.96e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 36 SGSGKSTLIKTVNGLEPVQQGEITVDGIVVNDKKtdlAKLRSRVGMVF-----QHFELFPHLSIIENLTL---AQVKVLK 107
Cdd:COG3845 293 AGNGQSELAEALAGLRPPASGSIRLDGEDITGLS---PRERRRLGVAYipedrLGRGLVPDMSVAENLILgryRRPPFSR 369
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 108 R---NKAPAREKALKLLER-----VGLSAHAnkfpAQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLDVM 179
Cdd:COG3845 370 GgflDRKAIRAFAEELIEEfdvrtPGPDTPA----RSLSGGNQQKVILARELSRDPKLLIAAQPTRGLDVGAIEFIHQRL 445
|
170 180 190
....*....|....*....|....*....|....*.
gi 446554041 180 VELANEGMTMMVVTHEMGFARKVANRVIFMDEGKII 215
Cdd:COG3845 446 LELRDAGAAVLLISEDLDEILALSDRIAVMYEGRIV 481
|
|
| PRK10575 |
PRK10575 |
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC; |
34-215 |
6.84e-16 |
|
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;
Pssm-ID: 182561 [Multi-domain] Cd Length: 265 Bit Score: 74.82 E-value: 6.84e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVNDKKTdlaKLRSR-VGMVFQHFELFPHLSIIENLTLAQVK---VLKRN 109
Cdd:PRK10575 44 GHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSS---KAFARkVAYLPQQLPAAEGMTVRELVAIGRYPwhgALGRF 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 110 KAPAREKALKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLDVMVELANE-GMT 188
Cdd:PRK10575 121 GAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLLLDEPTSALDIAHQVDVLALVHRLSQErGLT 200
|
170 180
....*....|....*....|....*..
gi 446554041 189 MMVVTHEMGFARKVANRVIFMDEGKII 215
Cdd:PRK10575 201 VIAVLHDINMAARYCDYLVALRGGEMI 227
|
|
| BtuD |
COG4138 |
ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism]; ... |
34-215 |
6.91e-16 |
|
ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism];
Pssm-ID: 443313 [Multi-domain] Cd Length: 248 Bit Score: 74.11 E-value: 6.91e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEPvQQGEITVDGIVVND-KKTDLAKLRsrvGMVFQHFELFPHLSIIENLTLAQVKVLKrnkAP 112
Cdd:COG4138 29 GPNGAGKSTLLARMAGLLP-GQGEILLNGRPLSDwSAAELARHR---AYLSQQQSPPFAMPVFQYLALHQPAGAS---SE 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 113 AREKAL-KLLERVGLSAHANKFPAQLSGGQQQRVAIARALC-----MDPIA--MLFDEPTSALDPEMINEVLDVMVELAN 184
Cdd:COG4138 102 AVEQLLaQLAEALGLEDKLSRPLTQLSGGEWQRVRLAAVLLqvwptINPEGqlLLLDEPMNSLDVAQQAALDRLLRELCQ 181
|
170 180 190
....*....|....*....|....*....|.
gi 446554041 185 EGMTMMVVTHEMGFARKVANRVIFMDEGKII 215
Cdd:COG4138 182 QGITVVMSSHDLNHTLRHADRVWLLKQGKLV 212
|
|
| SufC |
COG0396 |
Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, ... |
34-216 |
8.51e-16 |
|
Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440165 [Multi-domain] Cd Length: 245 Bit Score: 73.95 E-value: 8.51e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLE--PVQQGEITVDGIVVNDKKTDLaklRSRVG--MVFQHFELFPHLSIIENLTLAqVKVLKRN 109
Cdd:COG0396 33 GPNGSGKSTLAKVLMGHPkyEVTSGSILLDGEDILELSPDE---RARAGifLAFQYPVEIPGVSVSNFLRTA-LNARRGE 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 110 KAPARE---KALKLLERVGLSA-----HANkfpAQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLDVMVE 181
Cdd:COG0396 109 ELSAREflkLLKEKMKELGLDEdfldrYVN---EGFSGGEKKRNEILQMLLLEPKLAILDETDSGLDIDALRIVAEGVNK 185
|
170 180 190
....*....|....*....|....*....|....*....
gi 446554041 182 LANEGMTMMVVTHemgFAR----KVANRVIFMDEGKIIE 216
Cdd:COG0396 186 LRSPDRGILIITH---YQRildyIKPDFVHVLVDGRIVK 221
|
|
| PRK10762 |
PRK10762 |
D-ribose transporter ATP binding protein; Provisional |
34-219 |
9.37e-16 |
|
D-ribose transporter ATP binding protein; Provisional
Pssm-ID: 236755 [Multi-domain] Cd Length: 501 Bit Score: 75.81 E-value: 9.37e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVNDKKTDlAKLRSRVGMVFQHFELFPHLSIIENLTLAQVKVLKRNKAPA 113
Cdd:PRK10762 37 GENGAGKSTMMKVLTGIYTRDAGSILYLGKEVTFNGPK-SSQEAGIGIIHQELNLIPQLTIAENIFLGREFVNRFGRIDW 115
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 114 RE---KALKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLDVMVELANEGMTMM 190
Cdd:PRK10762 116 KKmyaEADKLLARLNLRFSSDKLVGELSIGEQQMVEIAKVLSFESKVIIMDEPTDALTDTETESLFRVIRELKSQGRGIV 195
|
170 180
....*....|....*....|....*....
gi 446554041 191 VVTHEMGFARKVANRVIFMDEGKIIEDSP 219
Cdd:PRK10762 196 YISHRLKEIFEICDDVTVFRDGQFIAERE 224
|
|
| TagH |
COG1134 |
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate ... |
1-222 |
1.12e-15 |
|
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440749 [Multi-domain] Cd Length: 245 Bit Score: 73.58 E-value: 1.12e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 1 MITLKNVSKWY----------------------GHFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQQGEI 58
Cdd:COG1134 4 MIEVENVSKSYrlyhepsrslkelllrrrrtrrEEFWALKDVSFEVERGESVGIIGRNGAGKSTLLKLIAGILEPTSGRV 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 59 TVDGIVVndkktdlAKLrsRVGMVFQhfelfPHLSIIENLTL-AQvkVLKRNKAPAREKalklLERV----GLSAHAN-- 131
Cdd:COG1134 84 EVNGRVS-------ALL--ELGAGFH-----PELTGRENIYLnGR--LLGLSRKEIDEK----FDEIvefaELGDFIDqp 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 132 -KFpaqLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLDVMVELANEGMTMMVVTHEMGFARKVANRVIFMD 210
Cdd:COG1134 144 vKT---YSSGMRARLAFAVATAVDPDILLVDEVLAVGDAAFQKKCLARIRELRESGRTVIFVSHSMGAVRRLCDRAIWLE 220
|
250
....*....|...
gi 446554041 211 EGKIIED-SPKDA 222
Cdd:COG1134 221 KGRLVMDgDPEEV 233
|
|
| araG |
PRK11288 |
L-arabinose ABC transporter ATP-binding protein AraG; |
37-223 |
2.48e-15 |
|
L-arabinose ABC transporter ATP-binding protein AraG;
Pssm-ID: 183077 [Multi-domain] Cd Length: 501 Bit Score: 74.56 E-value: 2.48e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 37 GSGKSTLIKTVNGLEPVQQGEITVDGIVVNDKKTDLAklrSRVGMVF----QHFE-LFPHLSIIENLTLAQvkvlKRNKA 111
Cdd:PRK11288 289 GAGRSELMKLLYGATRRTAGQVYLDGKPIDIRSPRDA---IRAGIMLcpedRKAEgIIPVHSVADNINISA----RRHHL 361
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 112 PA---------REKALKLLERVGL-SAHANKFPAQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLDVMVE 181
Cdd:PRK11288 362 RAgclinnrweAENADRFIRSLNIkTPSREQLIMNLSGGNQQKAILGRWLSEDMKVILLDEPTRGIDVGAKHEIYNVIYE 441
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 446554041 182 LANEGMTMMVVTHE----MGfarkVANRVIFMDEGKIIEDSPKDAF 223
Cdd:PRK11288 442 LAAQGVAVLFVSSDlpevLG----VADRIVVMREGRIAGELAREQA 483
|
|
| PRK10762 |
PRK10762 |
D-ribose transporter ATP binding protein; Provisional |
33-214 |
2.89e-15 |
|
D-ribose transporter ATP binding protein; Provisional
Pssm-ID: 236755 [Multi-domain] Cd Length: 501 Bit Score: 74.27 E-value: 2.89e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 33 CGPSGSGKSTLIKTVNGLEPVQQGEITVDG--IVVNDKKTDLA-------KLRSRVGMVFQhfelfphLSIIENLTLAQV 103
Cdd:PRK10762 284 SGLMGAGRTELMKVLYGALPRTSGYVTLDGheVVTRSPQDGLAngivyisEDRKRDGLVLG-------MSVKENMSLTAL 356
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 104 KVLKRN----------------------KAPAREKALKLLervglsahankfpaqlSGGQQQRVAIARALCMDPIAMLFD 161
Cdd:PRK10762 357 RYFSRAggslkhadeqqavsdfirlfniKTPSMEQAIGLL----------------SGGNQQKVAIARGLMTRPKVLILD 420
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 446554041 162 EPTSALDPEMINEVLDVMVELANEGMTMMVVTHEMGFARKVANRVIFMDEGKI 214
Cdd:PRK10762 421 EPTRGVDVGAKKEIYQLINQFKAEGLSIILVSSEMPEVLGMSDRILVMHEGRI 473
|
|
| ABC_KpsT_Wzt |
cd03220 |
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC ... |
2-217 |
3.57e-15 |
|
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC transporter subfamily is involved in extracellular polysaccharide export. Among the variety of membrane-linked or extracellular polysaccharides excreted by bacteria, only capsular polysaccharides, lipopolysaccharides, and teichoic acids have been shown to be exported by ABC transporters. A typical system is made of a conserved integral membrane and an ABC. In addition to these proteins, capsular polysaccharide exporter systems require two 'accessory' proteins to perform their function: a periplasmic (E.coli) or a lipid-anchored outer membrane protein called OMA (Neisseria meningitidis and Haemophilus influenza) and a cytoplasmic membrane protein MPA2.
Pssm-ID: 213187 [Multi-domain] Cd Length: 224 Bit Score: 71.79 E-value: 3.57e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 2 ITLKNVSKWY----------------------GHFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQQGEIT 59
Cdd:cd03220 1 IELENVSKSYptykggssslkklgilgrkgevGEFWALKDVSFEVPRGERIGLIGRNGAGKSTLLRLLAGIYPPDSGTVT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 60 VDGIVVndkktdlAKLrsRVGMVFQhfelfPHLSIIENLTL-AQVKVLKRNKAPAREKAlkLLERVGLSAHANKFPAQLS 138
Cdd:cd03220 81 VRGRVS-------SLL--GLGGGFN-----PELTGRENIYLnGRLLGLSRKEIDEKIDE--IIEFSELGDFIDLPVKTYS 144
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446554041 139 GGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLDVMVELANEGMTMMVVTHEMGFARKVANRVIFMDEGKIIED 217
Cdd:cd03220 145 SGMKARLAFAIATALEPDILLIDEVLAVGDAAFQEKCQRRLRELLKQGKTVILVSHDPSSIKRLCDRALVLEKGKIRFD 223
|
|
| ABCC_NFT1 |
cd03369 |
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type ... |
34-219 |
5.00e-15 |
|
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type transporter 1). NFT1 belongs to the MRP (multidrug resistance-associated protein) family of ABC transporters. Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213269 [Multi-domain] Cd Length: 207 Bit Score: 71.29 E-value: 5.00e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEPVQQGEITVDGIvvNDKKTDLAKLRSRVGMVFQHFELFPHlSIIENLTlaqvkvlKRNKAPA 113
Cdd:cd03369 41 GRTGAGKSTLILALFRFLEAEEGKIEIDGI--DISTIPLEDLRSSLTIIPQDPTLFSG-TIRSNLD-------PFDEYSD 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 114 RE--KALKLLERvGLSahankfpaqLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLDVMVELANeGMTMMV 191
Cdd:cd03369 111 EEiyGALRVSEG-GLN---------LSQGQRQLLCLARALLKRPRVLVLDEATASIDYATDALIQKTIREEFT-NSTILT 179
|
170 180 190
....*....|....*....|....*....|.
gi 446554041 192 VTHEMgfaRKVA--NRVIFMDEGKIIE-DSP 219
Cdd:cd03369 180 IAHRL---RTIIdyDKILVMDAGEVKEyDHP 207
|
|
| PRK11147 |
PRK11147 |
ABC transporter ATPase component; Reviewed |
34-215 |
1.39e-14 |
|
ABC transporter ATPase component; Reviewed
Pssm-ID: 236861 [Multi-domain] Cd Length: 635 Bit Score: 72.29 E-value: 1.39e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVndkktdLAKL-----RSRVGMVF-----------QHFELFPHLSII-- 95
Cdd:PRK11147 36 GRNGAGKSTLMKILNGEVLLDDGRIIYEQDLI------VARLqqdppRNVEGTVYdfvaegieeqaEYLKRYHDISHLve 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 96 -----ENLT-LAQVK-VLKRNKAPAREKALK-LLERVGLSAHANKfpAQLSGGQQQRVAIARALCMDPIAMLFDEPTSAL 167
Cdd:PRK11147 110 tdpseKNLNeLAKLQeQLDHHNLWQLENRINeVLAQLGLDPDAAL--SSLSGGWLRKAALGRALVSNPDVLLLDEPTNHL 187
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 446554041 168 DPEMInEVLDVMveLANEGMTMMVVTHEMGFARKVANRVIFMDEGKII 215
Cdd:PRK11147 188 DIETI-EWLEGF--LKTFQGSIIFISHDRSFIRNMATRIVDLDRGKLV 232
|
|
| ABCD_peroxisomal_ALDP |
cd03223 |
ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding ... |
34-194 |
2.03e-14 |
|
ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding cassette transporter (Pat) is involved in the import of very long-chain fatty acids (VLCFA) into the peroxisome. The peroxisomal membrane forms a permeability barrier for a wide variety of metabolites required for and formed during fatty acid beta-oxidation. To communicate with the cytoplasm and mitochondria, peroxisomes need dedicated proteins to transport such hydrophilic molecules across their membranes. X-linked adrenoleukodystrophy (X-ALD) is caused by mutations in the ALD gene, which encodes ALDP (adrenoleukodystrophy protein ), a peroxisomal integral membrane protein that is a member of the ATP-binding cassette (ABC) transporter protein family. The disease is characterized by a striking and unpredictable variation in phenotypic expression. Phenotypes include the rapidly progressive childhood cerebral form (CCALD), the milder adult form, adrenomyeloneuropathy (AMN), and variants without neurologic involvement (i.e. asymptomatic).
Pssm-ID: 213190 [Multi-domain] Cd Length: 166 Bit Score: 68.72 E-value: 2.03e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEPVQQGEITVDGivvndkktdlaklRSRVGMVFQHfelfPHLSIienLTLaqvkvlkrnkapa 113
Cdd:cd03223 34 GPSGTGKSSLFRALAGLWPWGSGRIGMPE-------------GEDLLFLPQR----PYLPL---GTL------------- 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 114 REKALKLLERVglsahankfpaqLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLDVMVElanEGMTMMVVT 193
Cdd:cd03223 81 REQLIYPWDDV------------LSGGEQQRLAFARLLLHKPKFVFLDEATSALDEESEDRLYQLLKE---LGITVISVG 145
|
.
gi 446554041 194 H 194
Cdd:cd03223 146 H 146
|
|
| PRK10789 |
PRK10789 |
SmdA family multidrug ABC transporter permease/ATP-binding protein; |
33-227 |
3.03e-14 |
|
SmdA family multidrug ABC transporter permease/ATP-binding protein;
Pssm-ID: 182732 [Multi-domain] Cd Length: 569 Bit Score: 71.28 E-value: 3.03e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 33 CGPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVNDKKTDlaKLRSRVGMVFQHFELFPHlSIIENLTL-------AQVKV 105
Cdd:PRK10789 347 CGPTGSGKSTLLSLIQRHFDVSEGDIRFHDIPLTKLQLD--SWRSRLAVVSQTPFLFSD-TVANNIALgrpdatqQEIEH 423
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 106 LKRnKAPAREKALKLLErvGLSAHANKFPAQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLDVMVELAnE 185
Cdd:PRK10789 424 VAR-LASVHDDILRLPQ--GYDTEVGERGVMLSGGQKQRISIARALLLNAEILILDDALSAVDGRTEHQILHNLRQWG-E 499
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 446554041 186 GMTMMVVTHEMGfARKVANRVIFMDEGKIIEDSPKDAFFDNP 227
Cdd:PRK10789 500 GRTVIISAHRLS-ALTEASEILVMQHGHIAQRGNHDQLAQQS 540
|
|
| PRK15439 |
PRK15439 |
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional |
34-222 |
4.65e-14 |
|
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
Pssm-ID: 185336 [Multi-domain] Cd Length: 510 Bit Score: 70.85 E-value: 4.65e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVNDKKTdlaKLRSRVGMVF-----QHFELFPHLSIIEN---LTLAQVKV 105
Cdd:PRK15439 296 GVVGAGRTELAETLYGLRPARGGRIMLNGKEINALST---AQRLARGLVYlpedrQSSGLYLDAPLAWNvcaLTHNRRGF 372
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 106 LKRnkaPAREKALklLER----VGLS-AHANKFPAQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLDVMV 180
Cdd:PRK15439 373 WIK---PARENAV--LERyrraLNIKfNHAEQAARTLSGGNQQKVLIAKCLEASPQLLIVDEPTRGVDVSARNDIYQLIR 447
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 446554041 181 ELANEGMTMMVVTHEMGFARKVANRVIFMDEGKIIEDSPKDA 222
Cdd:PRK15439 448 SIAAQNVAVLFISSDLEEIEQMADRVLVMHQGEISGALTGAA 489
|
|
| MK0520 |
COG2401 |
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction ... |
34-194 |
4.87e-14 |
|
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction only];
Pssm-ID: 441957 [Multi-domain] Cd Length: 222 Bit Score: 68.83 E-value: 4.87e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEPVQQGEITVDgivvndkktdlaklrsrvgmvFQHFELFPHLSIIENLTLAQVKVLkrnkapa 113
Cdd:COG2401 63 GASGSGKSTLLRLLAGALKGTPVAGCVD---------------------VPDNQFGREASLIDAIGRKGDFKD------- 114
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 114 rekALKLLERVGLSAHANKF--PAQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLDVMVELANE-GMTMM 190
Cdd:COG2401 115 ---AVELLNAVGLSDAVLWLrrFKELSTGQKFRFRLALLLAERPKLLVIDEFCSHLDRQTAKRVARNLQKLARRaGITLV 191
|
....
gi 446554041 191 VVTH 194
Cdd:COG2401 192 VATH 195
|
|
| PRK13543 |
PRK13543 |
heme ABC exporter ATP-binding protein CcmA; |
34-194 |
8.38e-14 |
|
heme ABC exporter ATP-binding protein CcmA;
Pssm-ID: 184129 [Multi-domain] Cd Length: 214 Bit Score: 67.95 E-value: 8.38e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEPVQQGEITVDGivvndkKTDLAKLRSRVGMVFQHFE-LFPHLSIIENLT-LAQVKVLKRNKA 111
Cdd:PRK13543 44 GDNGAGKTTLLRVLAGLLHVESGQIQIDG------KTATRGDRSRFMAYLGHLPgLKADLSTLENLHfLCGLHGRRAKQM 117
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 112 PAREKALkllerVGLSAHANKFPAQLSGGQQQRVAIARaLCMDPIAM-LFDEPTSALDPEMINEVLDVMVELANEGMTMM 190
Cdd:PRK13543 118 PGSALAI-----VGLAGYEDTLVRQLSAGQKKRLALAR-LWLSPAPLwLLDEPYANLDLEGITLVNRMISAHLRGGGAAL 191
|
....
gi 446554041 191 VVTH 194
Cdd:PRK13543 192 VTTH 195
|
|
| PRK13549 |
PRK13549 |
xylose transporter ATP-binding subunit; Provisional |
37-221 |
8.45e-14 |
|
xylose transporter ATP-binding subunit; Provisional
Pssm-ID: 184134 [Multi-domain] Cd Length: 506 Bit Score: 69.96 E-value: 8.45e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 37 GSGKSTLIKTVNGLEP-VQQGEITVDGIVVnDKKTDLAKLRSRVGMVFQ---HFELFPHLSIIENLTLAqvkVLKR---- 108
Cdd:PRK13549 298 GAGRTELVQCLFGAYPgRWEGEIFIDGKPV-KIRNPQQAIAQGIAMVPEdrkRDGIVPVMGVGKNITLA---ALDRftgg 373
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 109 ---NKAPAREKALKLLERVGL-SAHANKFPAQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLDVMVELAN 184
Cdd:PRK13549 374 sriDDAAELKTILESIQRLKVkTASPELAIARLSGGNQQKAVLAKCLLLNPKILILDEPTRGIDVGAKYEIYKLINQLVQ 453
|
170 180 190
....*....|....*....|....*....|....*..
gi 446554041 185 EGMTMMVVTHEMGFARKVANRVIFMDEGKIIEDSPKD 221
Cdd:PRK13549 454 QGVAIIVISSELPEVLGLSDRVLVMHEGKLKGDLINH 490
|
|
| hmuV |
PRK13547 |
heme ABC transporter ATP-binding protein; |
1-221 |
9.92e-14 |
|
heme ABC transporter ATP-binding protein;
Pssm-ID: 184132 [Multi-domain] Cd Length: 272 Bit Score: 68.70 E-value: 9.92e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 1 MITLKNVSKWYGHFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNG--LEPVQQGEITVDG-IVVNDK------KTD 71
Cdd:PRK13547 1 MLTADHLHVARRHRAILRDLSLRIEPGRVTALLGRNGAGKSTLLKALAGdlTGGGAPRGARVTGdVTLNGEplaaidAPR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 72 LAKLRSRVGMVFQhfELFPhLSIIENLTLAQVKVLKRNKAPA---REKALKLLERVGLSAHANKFPAQLSGGQQQRVAIA 148
Cdd:PRK13547 81 LARLRAVLPQAAQ--PAFA-FSAREIVLLGRYPHARRAGALThrdGEIAWQALALAGATALVGRDVTTLSGGELARVQFA 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 149 RALCM---------DPIAMLFDEPTSALDPEMINEVLDVMVELANE-GMTMMVVTHEMGFARKVANRVIFMDEGKIIED- 217
Cdd:PRK13547 158 RVLAQlwpphdaaqPPRYLLLDEPTAALDLAHQHRLLDTVRRLARDwNLGVLAIVHDPNLAARHADRIAMLADGAIVAHg 237
|
....
gi 446554041 218 SPKD 221
Cdd:PRK13547 238 APAD 241
|
|
| Rli1 |
COG1245 |
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ... |
34-196 |
3.86e-13 |
|
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];
Pssm-ID: 440858 [Multi-domain] Cd Length: 592 Bit Score: 68.27 E-value: 3.86e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGlepvqqgEITVD-GIVVNDKKTDlaklrsrvgMVFQHF---ELFPHLSIIENLTLAQV------ 103
Cdd:COG1245 106 GPNGIGKSTALKILSG-------ELKPNlGDYDEEPSWD---------EVLKRFrgtELQDYFKKLANGEIKVAhkpqyv 169
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 104 ----KVLKRN------KAPAREKALKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDpemIN 173
Cdd:COG1245 170 dlipKVFKGTvrelleKVDERGKLDELAEKLGLENILDRDISELSGGELQRVAIAAALLRDADFYFFDEPSSYLD---IY 246
|
170 180
....*....|....*....|....*.
gi 446554041 174 E---VLDVMVELANEGMTMMVVTHEM 196
Cdd:COG1245 247 QrlnVARLIRELAEEGKYVLVVEHDL 272
|
|
| rim_protein |
TIGR01257 |
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ... |
34-212 |
1.13e-12 |
|
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]
Pssm-ID: 130324 [Multi-domain] Cd Length: 2272 Bit Score: 67.35 E-value: 1.13e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEPVQQGEITVDGivvndkktdlAKLRSRVGMVFQHFELFPHLSIIENLTLAQVKVL---KRNK 110
Cdd:TIGR01257 1972 GVNGAGKTTTFKMLTGDTTVTSGDATVAG----------KSILTNISDVHQNMGYCPQFDAIDDLLTGREHLYlyaRLRG 2041
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 111 APAREkalklLERV--------GLSAHANKFPAQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLDVMVEL 182
Cdd:TIGR01257 2042 VPAEE-----IEKVanwsiqslGLSLYADRLAGTYSGGNKRKLSTAIALIGCPPLVLLDEPTTGMDPQARRMLWNTIVSI 2116
|
170 180 190
....*....|....*....|....*....|
gi 446554041 183 ANEGMTMMVVTHEMGFARKVANRVIFMDEG 212
Cdd:TIGR01257 2117 IREGRAVVLTSHSMEECEALCTRLAIMVKG 2146
|
|
| PRK13538 |
PRK13538 |
cytochrome c biogenesis heme-transporting ATPase CcmA; |
34-199 |
1.30e-12 |
|
cytochrome c biogenesis heme-transporting ATPase CcmA;
Pssm-ID: 184125 [Multi-domain] Cd Length: 204 Bit Score: 64.44 E-value: 1.30e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEPVQQGEITVDGivvndkkTDLAKLRSRVgmvfqHFELF---------PHLSIIENLTLAQvk 104
Cdd:PRK13538 34 GPNGAGKTSLLRILAGLARPDAGEVLWQG-------EPIRRQRDEY-----HQDLLylghqpgikTELTALENLRFYQ-- 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 105 vlkRNKAPAREKAL-KLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLDVMVE-L 182
Cdd:PRK13538 100 ---RLHGPGDDEALwEALAQVGLAGFEDVPVRQLSAGQQRRVALARLWLTRAPLWILDEPFTAIDKQGVARLEALLAQhA 176
|
170
....*....|....*..
gi 446554041 183 ANEGMTMMVVTHEMGFA 199
Cdd:PRK13538 177 EQGGMVILTTHQDLPVA 193
|
|
| PRK10982 |
PRK10982 |
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional |
34-219 |
4.43e-12 |
|
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
Pssm-ID: 182880 [Multi-domain] Cd Length: 491 Bit Score: 65.14 E-value: 4.43e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVNDKKTDLAkLRSRVGMVFQHFELFPHLSIIENLTLA----------QV 103
Cdd:PRK10982 31 GENGAGKSTLLKCLFGIYQKDSGSILFQGKEIDFKSSKEA-LENGISMVHQELNLVLQRSVMDNMWLGryptkgmfvdQD 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 104 KVLKRNKAPAREKALKLLERVGLsahankfpAQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLDVMVELA 183
Cdd:PRK10982 110 KMYRDTKAIFDELDIDIDPRAKV--------ATLSVSQMQMIEIAKAFSYNAKIVIMDEPTSSLTEKEVNHLFTIIRKLK 181
|
170 180 190
....*....|....*....|....*....|....*.
gi 446554041 184 NEGMTMMVVTHEMGFARKVANRVIFMDEGKIIEDSP 219
Cdd:PRK10982 182 ERGCGIVYISHKMEEIFQLCDEITILRDGQWIATQP 217
|
|
| ABC2_perm_RbbA |
NF033858 |
ribosome-associated ATPase/putative transporter RbbA; |
34-221 |
7.73e-12 |
|
ribosome-associated ATPase/putative transporter RbbA;
Pssm-ID: 468210 [Multi-domain] Cd Length: 907 Bit Score: 64.38 E-value: 7.73e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEPVQQGEITVDGivvndkkTDLAKLRSR-------------VGMvfqhfELFPHLSIIENL-- 98
Cdd:NF033858 34 GPDGVGKSSLLSLIAGARKIQQGRVEVLG-------GDMADARHRravcpriaympqgLGK-----NLYPTLSVFENLdf 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 99 --TL-AQvkvlkrNKAPAREKALKLLERVGLSAHANKfPA-QLSGGQQQRVAIARALCMDPIAMLFDEPTSALDP----- 169
Cdd:NF033858 102 fgRLfGQ------DAAERRRRIDELLRATGLAPFADR-PAgKLSGGMKQKLGLCCALIHDPDLLILDEPTTGVDPlsrrq 174
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 446554041 170 --EMINEvldvmVELANEGMTMMVVTHEM----GFARKVAnrvifMDEGKII-EDSPKD 221
Cdd:NF033858 175 fwELIDR-----IRAERPGMSVLVATAYMeeaeRFDWLVA-----MDAGRVLaTGTPAE 223
|
|
| PRK13409 |
PRK13409 |
ribosome biogenesis/translation initiation ATPase RLI; |
34-196 |
9.79e-12 |
|
ribosome biogenesis/translation initiation ATPase RLI;
Pssm-ID: 184037 [Multi-domain] Cd Length: 590 Bit Score: 64.06 E-value: 9.79e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNG-LEP---VQQGEITVDGIVVNDKKTDL----AKLRS---RVGMVFQHFELFPhlsiienltlaq 102
Cdd:PRK13409 106 GPNGIGKTTAVKILSGeLIPnlgDYEEEPSWDEVLKRFRGTELqnyfKKLYNgeiKVVHKPQYVDLIP------------ 173
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 103 vKVLKRN------KAPAREKALKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDpemINE-- 174
Cdd:PRK13409 174 -KVFKGKvrellkKVDERGKLDEVVERLGLENILDRDISELSGGELQRVAIAAALLRDADFYFFDEPTSYLD---IRQrl 249
|
170 180
....*....|....*....|...
gi 446554041 175 -VLDVMVELAnEGMTMMVVTHEM 196
Cdd:PRK13409 250 nVARLIRELA-EGKYVLVVEHDL 271
|
|
| PRK10790 |
PRK10790 |
SmdB family multidrug efflux ABC transporter permease/ATP-binding protein; |
2-168 |
1.08e-11 |
|
SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;
Pssm-ID: 182733 [Multi-domain] Cd Length: 592 Bit Score: 63.97 E-value: 1.08e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 2 ITLKNVSKWYGHFQ-VLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVNdkKTDLAKLRSRVG 80
Cdd:PRK10790 341 IDIDNVSFAYRDDNlVLQNINLSVPSRGFVALVGHTGSGKSTLASLLMGYYPLTEGEIRLDGRPLS--SLSHSVLRQGVA 418
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 81 MVFQHfelfPHL---SIIENLTLAqvkvlkRNKapAREKALKLLERVGLSAHANKFPA-----------QLSGGQQQRVA 146
Cdd:PRK10790 419 MVQQD----PVVladTFLANVTLG------RDI--SEEQVWQALETVQLAELARSLPDglytplgeqgnNLSVGQKQLLA 486
|
170 180
....*....|....*....|..
gi 446554041 147 IARALCMDPIAMLFDEPTSALD 168
Cdd:PRK10790 487 LARVLVQTPQILILDEATANID 508
|
|
| PRK10522 |
PRK10522 |
multidrug transporter membrane component/ATP-binding component; Provisional |
34-216 |
1.31e-11 |
|
multidrug transporter membrane component/ATP-binding component; Provisional
Pssm-ID: 236707 [Multi-domain] Cd Length: 547 Bit Score: 63.45 E-value: 1.31e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVNDKktDLAKLRSRVGMVFQHFELFPHLsiienltlaqvkVLKRNKAPA 113
Cdd:PRK10522 356 GGNGSGKSTLAMLLTGLYQPQSGEILLDGKPVTAE--QPEDYRKLFSAVFTDFHLFDQL------------LGPEGKPAN 421
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 114 REKALKLLERVG----LSAHANKFP-AQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLDVMVELANE-GM 187
Cdd:PRK10522 422 PALVEKWLERLKmahkLELEDGRISnLKLSKGQKKRLALLLALAEERDILLLDEWAADQDPHFRREFYQVLLPLLQEmGK 501
|
170 180
....*....|....*....|....*....
gi 446554041 188 TMMVVTHEMGFARKvANRVIFMDEGKIIE 216
Cdd:PRK10522 502 TIFAISHDDHYFIH-ADRLLEMRNGQLSE 529
|
|
| ABC_RNaseL_inhibitor_domain2 |
cd03237 |
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ... |
34-210 |
1.40e-11 |
|
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity of more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.
Pssm-ID: 213204 [Multi-domain] Cd Length: 246 Bit Score: 62.43 E-value: 1.40e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVNDKKTDL-AKLRSRVgmvfQHFeLFPHLSIIENLTLAQVKVLKrnkaP 112
Cdd:cd03237 32 GPNGIGKTTFIKMLAGVLKPDEGDIEIELDTVSYKPQYIkADYEGTV----RDL-LSSITKDFYTHPYFKTEIAK----P 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 113 AreKALKLLERvglsahanKFPaQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPE---MINEVLDVMVElaNEGMTM 189
Cdd:cd03237 103 L--QIEQILDR--------EVP-ELSGGELQRVAIAACLSKDADIYLLDEPSAYLDVEqrlMASKVIRRFAE--NNEKTA 169
|
170 180
....*....|....*....|.
gi 446554041 190 MVVTHEMGFARKVANRVIFMD 210
Cdd:cd03237 170 FVVEHDIIMIDYLADRLIVFE 190
|
|
| PTZ00265 |
PTZ00265 |
multidrug resistance protein (mdr1); Provisional |
56-236 |
1.68e-11 |
|
multidrug resistance protein (mdr1); Provisional
Pssm-ID: 240339 [Multi-domain] Cd Length: 1466 Bit Score: 63.51 E-value: 1.68e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 56 GEITVDGIVVNDkkTDLAKLRSRVGMVFQHFELFpHLSIIENLTLAQVKVLKRN-KAPAREKAL-KLLERVGLSAHANKF 133
Cdd:PTZ00265 1277 GKILLDGVDICD--YNLKDLRNLFSIVSQEPMLF-NMSIYENIKFGKEDATREDvKRACKFAAIdEFIESLPNKYDTNVG 1353
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 134 P--AQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLDVMVELANEG-MTMMVVTHemgfarKVANrvifmd 210
Cdd:PTZ00265 1354 PygKSLSGGQKQRIAIARALLREPKILLLDEATSSLDSNSEKLIEKTIVDIKDKAdKTIITIAH------RIAS------ 1421
|
170 180
....*....|....*....|....*.
gi 446554041 211 egkiIEDSPKDAFFDNPksDRAKDFL 236
Cdd:PTZ00265 1422 ----IKRSDKIVVFNNP--DRTGSFV 1441
|
|
| MRP_assoc_pro |
TIGR00957 |
multi drug resistance-associated protein (MRP); This model describes multi drug ... |
34-225 |
4.24e-11 |
|
multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]
Pssm-ID: 188098 [Multi-domain] Cd Length: 1522 Bit Score: 62.27 E-value: 4.24e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVndkktdlaklrsrvgmvfqhfeLFPHLSIIENLTLAQVKVLKRNKAPA 113
Cdd:TIGR00957 671 GQVGCGKSSLLSALLAEMDKVEGHVHMKGSVA----------------------YVPQQAWIQNDSLRENILFGKALNEK 728
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 114 REKALklLERVGLSAHANKFPA-----------QLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLDVMVel 182
Cdd:TIGR00957 729 YYQQV--LEACALLPDLEILPSgdrteigekgvNLSGGQKQRVSLARAVYSNADIYLFDDPLSAVDAHVGKHIFEHVI-- 804
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 446554041 183 ANEGM----TMMVVTHEMGFARKVaNRVIFMDEGKIIEDSPKDAFFD 225
Cdd:TIGR00957 805 GPEGVlknkTRILVTHGISYLPQV-DVIIVMSGGKISEMGSYQELLQ 850
|
|
| PLN03232 |
PLN03232 |
ABC transporter C family member; Provisional |
34-217 |
4.81e-11 |
|
ABC transporter C family member; Provisional
Pssm-ID: 215640 [Multi-domain] Cd Length: 1495 Bit Score: 62.30 E-value: 4.81e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNG-LEPVQQGEITVDGIVVndkktdlaklrsrvgmvfqhfeLFPHLSIIENLTLAQVKVLKRNKAP 112
Cdd:PLN03232 650 GGTGEGKTSLISAMLGeLSHAETSSVVIRGSVA----------------------YVPQVSWIFNATVRENILFGSDFES 707
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 113 arEKALKLLERVGLSAHANKFPAQ-----------LSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLDVMVE 181
Cdd:PLN03232 708 --ERYWRAIDVTALQHDLDLLPGRdlteigergvnISGGQKQRVSMARAVYSNSDIYIFDDPLSALDAHVAHQVFDSCMK 785
|
170 180 190
....*....|....*....|....*....|....*.
gi 446554041 182 LANEGMTMMVVTHEMGFARKVaNRVIFMDEGKIIED 217
Cdd:PLN03232 786 DELKGKTRVLVTNQLHFLPLM-DRIILVSEGMIKEE 820
|
|
| PLN03130 |
PLN03130 |
ABC transporter C family member; Provisional |
137-217 |
5.73e-11 |
|
ABC transporter C family member; Provisional
Pssm-ID: 215595 [Multi-domain] Cd Length: 1622 Bit Score: 62.06 E-value: 5.73e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 137 LSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLDVMVELANEGMTMMVVTHEMGFARKVaNRVIFMDEGKIIE 216
Cdd:PLN03130 741 ISGGQKQRVSMARAVYSNSDVYIFDDPLSALDAHVGRQVFDKCIKDELRGKTRVLVTNQLHFLSQV-DRIILVHEGMIKE 819
|
.
gi 446554041 217 D 217
Cdd:PLN03130 820 E 820
|
|
| ABC_RNaseL_inhibitor_domain1 |
cd03236 |
The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ... |
34-196 |
9.83e-11 |
|
The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI s are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLIs have an N-terminal Fe-S domain and two nucleotide binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.
Pssm-ID: 213203 [Multi-domain] Cd Length: 255 Bit Score: 60.07 E-value: 9.83e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNG-LEP---VQQGEITVDGIVVNDKKTDL----AKLRS---RVGMVFQHFELFPHL---SIIENLt 99
Cdd:cd03236 33 GPNGIGKSTALKILAGkLKPnlgKFDDPPDWDEILDEFRGSELqnyfTKLLEgdvKVIVKPQYVDLIPKAvkgKVGELL- 111
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 100 laqvkvlkrNKAPAREKALKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLDVM 179
Cdd:cd03236 112 ---------KKKDERGKLDELVDQLELRHVLDRNIDQLSGGELQRVAIAAALARDADFYFFDEPSSYLDIKQRLNAARLI 182
|
170
....*....|....*..
gi 446554041 180 VELANEGMTMMVVTHEM 196
Cdd:cd03236 183 RELAEDDNYVLVVEHDL 199
|
|
| PRK03695 |
PRK03695 |
vitamin B12-transporter ATPase; Provisional |
34-215 |
2.34e-10 |
|
vitamin B12-transporter ATPase; Provisional
Pssm-ID: 235150 [Multi-domain] Cd Length: 248 Bit Score: 58.79 E-value: 2.34e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEPvQQGEITVDGIVVND-KKTDLAKLRSRV--------GM-VFQHFELFPHLSIIENLTLAQV 103
Cdd:PRK03695 29 GPNGAGKSTLLARMAGLLP-GSGSIQFAGQPLEAwSAAELARHRAYLsqqqtppfAMpVFQYLTLHQPDKTRTEAVASAL 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 104 KVLKRnkaparekALKLLERVGLSAHankfpaQLSGGQQQRVAIArALCM------DPIA--MLFDEPTSALDPEMINeV 175
Cdd:PRK03695 108 NEVAE--------ALGLDDKLGRSVN------QLSGGEWQRVRLA-AVVLqvwpdiNPAGqlLLLDEPMNSLDVAQQA-A 171
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 446554041 176 LD-VMVELANEGMTMMVVTHEMGFARKVANRVIFMDEGKII 215
Cdd:PRK03695 172 LDrLLSELCQQGIAVVMSSHDLNHTLRHADRVWLLKQGKLL 212
|
|
| ABC_ABC_ChvD |
TIGR03719 |
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ... |
34-215 |
3.89e-10 |
|
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.
Pssm-ID: 274744 [Multi-domain] Cd Length: 552 Bit Score: 59.18 E-value: 3.89e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEPVQQGEITV-DGIvvndkktdlaklrsRVGMVFQHFELFPHLSIIENLTLA---QVKVLKR- 108
Cdd:TIGR03719 38 GLNGAGKSTLLRIMAGVDKDFNGEARPqPGI--------------KVGYLPQEPQLDPTKTVRENVEEGvaeIKDALDRf 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 109 ---NKAPAREKAL--KLLERVG-------------------LSAHANKFP------AQLSGGQQQRVAIARALCMDPIAM 158
Cdd:TIGR03719 104 neiSAKYAEPDADfdKLAAEQAelqeiidaadawdldsqleIAMDALRCPpwdadvTKLSGGERRRVALCRLLLSKPDML 183
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 446554041 159 LFDEPTSALDPEMInevldVMVE--LANEGMTMMVVTHEMGFARKVANRVIFMDEGKII 215
Cdd:TIGR03719 184 LLDEPTNHLDAESV-----AWLErhLQEYPGTVVAVTHDRYFLDNVAGWILELDRGRGI 237
|
|
| 3a01203 |
TIGR00954 |
Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, ... |
33-194 |
1.13e-09 |
|
Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]
Pssm-ID: 273360 [Multi-domain] Cd Length: 659 Bit Score: 57.84 E-value: 1.13e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 33 CGPSGSGKSTLIKTVNGLEPVQQGEITV---------------------DGIVVNDKKTDLaklrSRVGMVFQHFElfph 91
Cdd:TIGR00954 484 CGPNGCGKSSLFRILGELWPVYGGRLTKpakgklfyvpqrpymtlgtlrDQIIYPDSSEDM----KRRGLSDKDLE---- 555
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 92 lSIIENLTLAQVkvLKRNkaparekalkllerVGLSAHANkFPAQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEM 171
Cdd:TIGR00954 556 -QILDNVQLTHI--LERE--------------GGWSAVQD-WMDVLSGGEKQRIAMARLFYHKPQFAILDECTSAVSVDV 617
|
170 180
....*....|....*....|....
gi 446554041 172 inevLDVMVELANE-GMTMMVVTH 194
Cdd:TIGR00954 618 ----EGYMYRLCREfGITLFSVSH 637
|
|
| ABCG_PDR_domain1 |
cd03233 |
First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette ... |
34-215 |
1.29e-09 |
|
First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213200 [Multi-domain] Cd Length: 202 Bit Score: 56.12 E-value: 1.29e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEPVQ---QGEITVDGIvvnDKKTDLAKLRSRVGMVFQHFELFPHLSIIENLTLAqvkvlkrnk 110
Cdd:cd03233 40 GRPGSGCSTLLKALANRTEGNvsvEGDIHYNGI---PYKEFAEKYPGEIIYVSEEDVHFPTLTVRETLDFA--------- 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 111 aparekalkllervgLSAHANKFPAQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLDVMVELANE-GMTM 189
Cdd:cd03233 108 ---------------LRCKGNEFVRGISGGERKRVSIAEALVSRASVLCWDNSTRGLDSSTALEILKCIRTMADVlKTTT 172
|
170 180
....*....|....*....|....*..
gi 446554041 190 MV-VTHEMGFARKVANRVIFMDEGKII 215
Cdd:cd03233 173 FVsLYQASDEIYDLFDKVLVLYEGRQI 199
|
|
| 3a01205 |
TIGR00956 |
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other] |
14-239 |
1.78e-09 |
|
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273362 [Multi-domain] Cd Length: 1394 Bit Score: 57.43 E-value: 1.78e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 14 FQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTV----NGLEPVQQGEITVDGIVVNDKKTdlaKLRSRVGMVFQHFELF 89
Cdd:TIGR00956 74 FDILKPMDGLIKPGELTVVLGRPGSGCSTLLKTIasntDGFHIGVEGVITYDGITPEEIKK---HYRGDVVYNAETDVHF 150
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 90 PHLSIIENLTLAqvkvlKRNKAPA-REKALKLLERV-----------GLSaH------ANKFPAQLSGGQQQRVAIARAL 151
Cdd:TIGR00956 151 PHLTVGETLDFA-----ARCKTPQnRPDGVSREEYAkhiadvymatyGLS-HtrntkvGNDFVRGVSGGERKRVSIAEAS 224
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 152 CMDPIAMLFDEPTSALDPEMINEVLDVMVELANE-GMTMMVVTHEMG-FARKVANRVIFMDEGKIIEDSPKD---AFFDN 226
Cdd:TIGR00956 225 LGGAKIQCWDNATRGLDSATALEFIRALKTSANIlDTTPLVAIYQCSqDAYELFDKVIVLYEGYQIYFGPADkakQYFEK 304
|
250
....*....|....*...
gi 446554041 227 -----PKSDRAKDFLAKI 239
Cdd:TIGR00956 305 mgfkcPDRQTTADFLTSL 322
|
|
| PTZ00265 |
PTZ00265 |
multidrug resistance protein (mdr1); Provisional |
34-231 |
1.95e-09 |
|
multidrug resistance protein (mdr1); Provisional
Pssm-ID: 240339 [Multi-domain] Cd Length: 1466 Bit Score: 57.35 E-value: 1.95e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEPVQQGEItvdgiVVND----KKTDLAKLRSRVGMVFQHFELFPHlSIIENL--TLAQVKVL- 106
Cdd:PTZ00265 418 GESGCGKSTILKLIERLYDPTEGDI-----IINDshnlKDINLKWWRSKIGVVSQDPLLFSN-SIKNNIkySLYSLKDLe 491
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 107 ------------------KRNKAPAR---------------------------------EKALKLLERVGLSAHANKF-- 133
Cdd:PTZ00265 492 alsnyynedgndsqenknKRNSCRAKcagdlndmsnttdsneliemrknyqtikdsevvDVSKKVLIHDFVSALPDKYet 571
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 134 -----PAQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLDVMVEL-ANEGMTMMVVTHEMGFARkVANRVI 207
Cdd:PTZ00265 572 lvgsnASKLSGGQKQRISIARAIIRNPKILILDEATSSLDNKSEYLVQKTINNLkGNENRITIIIAHRLSTIR-YANTIF 650
|
250 260 270
....*....|....*....|....*....|...
gi 446554041 208 FM---------DEGKIIEDSPKDAFFDNPKSDR 231
Cdd:PTZ00265 651 VLsnrergstvDVDIIGEDPTKDNKENNNKNNK 683
|
|
| MRP_assoc_pro |
TIGR00957 |
multi drug resistance-associated protein (MRP); This model describes multi drug ... |
34-221 |
3.23e-09 |
|
multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]
Pssm-ID: 188098 [Multi-domain] Cd Length: 1522 Bit Score: 56.88 E-value: 3.23e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEPVQQGEITVDGIvvNDKKTDLAKLRSRVGMVFQHFELFPhlsiienltlaqvKVLKRNKAP- 112
Cdd:TIGR00957 1319 GRTGAGKSSLTLGLFRINESAEGEIIIDGL--NIAKIGLHDLRFKITIIPQDPVLFS-------------GSLRMNLDPf 1383
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 113 ---AREKALKLLERVGLSAHANKFPAQL-----------SGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINeVLDV 178
Cdd:TIGR00957 1384 sqySDEEVWWALELAHLKTFVSALPDKLdhecaeggenlSVGQRQLVCLARALLRKTKILVLDEATAAVDLETDN-LIQS 1462
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 446554041 179 MVELANEGMTMMVVTHEMGFARKVaNRVIFMDEGKIIE-DSPKD 221
Cdd:TIGR00957 1463 TIRTQFEDCTVLTIAHRLNTIMDY-TRVIVLDKGEVAEfGAPSN 1505
|
|
| ABC_UvrA |
cd03238 |
ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in ... |
34-212 |
3.43e-09 |
|
ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins, and UvrB having one ATP binding site that is structurally related to that of helicases.
Pssm-ID: 213205 [Multi-domain] Cd Length: 176 Bit Score: 54.64 E-value: 3.43e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTvnglepvqqgeitvdgIVVNDKKTDLAKLRSRvgmvfqhfelFPHLSIIenltlaqvkvlkrnkapa 113
Cdd:cd03238 28 GVSGSGKSTLVNE----------------GLYASGKARLISFLPK----------FSRNKLI------------------ 63
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 114 REKALKLLERVGLS-AHANKFPAQLSGGQQQRVAIARALC--MDPIAMLFDEPTSALDPEMINEVLDVMVELANEGMTMM 190
Cdd:cd03238 64 FIDQLQFLIDVGLGyLTLGQKLSTLSGGELQRVKLASELFsePPGTLFILDEPSTGLHQQDINQLLEVIKGLIDLGNTVI 143
|
170 180
....*....|....*....|..
gi 446554041 191 VVTHEMGFARKvANRVIFMDEG 212
Cdd:cd03238 144 LIEHNLDVLSS-ADWIIDFGPG 164
|
|
| ycf16 |
CHL00131 |
sulfate ABC transporter protein; Validated |
34-216 |
4.90e-09 |
|
sulfate ABC transporter protein; Validated
Pssm-ID: 214372 [Multi-domain] Cd Length: 252 Bit Score: 55.03 E-value: 4.90e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGlEP---VQQGEITVDGIVVNDKKTDlakLRSRVG--MVFQHFELFPHLSIIENLTLAQVKVLKR 108
Cdd:CHL00131 40 GPNGSGKSTLSKVIAG-HPaykILEGDILFKGESILDLEPE---ERAHLGifLAFQYPIEIPGVSNADFLRLAYNSKRKF 115
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 109 NKAPA----------REKalklLERVGLSAH-----ANKfpaQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMIN 173
Cdd:CHL00131 116 QGLPEldplefleiiNEK----LKLVGMDPSflsrnVNE---GFSGGEKKRNEILQMALLDSELAILDETDSGLDIDALK 188
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 446554041 174 EVLDVMVELANEGMTMMVVTHemgFARK----VANRVIFMDEGKIIE 216
Cdd:CHL00131 189 IIAEGINKLMTSENSIILITH---YQRLldyiKPDYVHVMQNGKIIK 232
|
|
| ABCG_PDR_domain2 |
cd03232 |
Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding ... |
34-195 |
7.28e-09 |
|
Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213199 [Multi-domain] Cd Length: 192 Bit Score: 53.79 E-value: 7.28e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLI------KTVNGLEpvqqGEITVDGIVVNDkktdlaKLRSRVGMVFQHFELFPHLSIIENLTLAqvkvlk 107
Cdd:cd03232 40 GESGAGKTTLLdvlagrKTAGVIT----GEILINGRPLDK------NFQRSTGYVEQQDVHSPNLTVREALRFS------ 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 108 rnkAPAREkalkllervglsahankfpaqLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLDVMVELANEGM 187
Cdd:cd03232 104 ---ALLRG---------------------LSVEQRKRLTIGVELAAKPSILFLDEPTSGLDSQAAYNIVRFLKKLADSGQ 159
|
....*...
gi 446554041 188 TMMVVTHE 195
Cdd:cd03232 160 AILCTIHQ 167
|
|
| ABCC_CFTR2 |
cd03289 |
ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator ... |
2-214 |
9.29e-09 |
|
ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.
Pssm-ID: 213256 [Multi-domain] Cd Length: 275 Bit Score: 54.48 E-value: 9.29e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 2 ITLKNVSKWY--GHFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQqGEITVDGivVNDKKTDLAKLRSRV 79
Cdd:cd03289 3 MTVKDLTAKYteGGNAVLENISFSISPGQRVGLLGRTGSGKSTLLSAFLRLLNTE-GDIQIDG--VSWNSVPLQKWRKAF 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 80 GMVFQHFELFPhlsiienltlaqvKVLKRNKAP----AREKALKLLERVGLSAHANKFPAQL-----------SGGQQQR 144
Cdd:cd03289 80 GVIPQKVFIFS-------------GTFRKNLDPygkwSDEEIWKVAEEVGLKSVIEQFPGQLdfvlvdggcvlSHGHKQL 146
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 145 VAIARALCMDPIAMLFDEPTSALDPEMInEVLDVMVELANEGMTMMVVTHEMGfARKVANRVIFMDEGKI 214
Cdd:cd03289 147 MCLARSVLSKAKILLLDEPSAHLDPITY-QVIRKTLKQAFADCTVILSEHRIE-AMLECQRFLVIEENKV 214
|
|
| ABCC_SUR2 |
cd03288 |
ATP-binding cassette domain 2 of the sulfonylurea receptor SUR; The SUR domain 2. The ... |
33-223 |
9.87e-09 |
|
ATP-binding cassette domain 2 of the sulfonylurea receptor SUR; The SUR domain 2. The sulfonylurea receptor SUR is an ATP binding cassette (ABC) protein of the ABCC/MRP family. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.
Pssm-ID: 213255 [Multi-domain] Cd Length: 257 Bit Score: 54.14 E-value: 9.87e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 33 CGPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVNdkKTDLAKLRSRVGMVFQHFELFPHlSIIENLTlAQVKVLKRNKAP 112
Cdd:cd03288 53 CGRTGSGKSSLSLAFFRMVDIFDGKIVIDGIDIS--KLPLHTLRSRLSIILQDPILFSG-SIRFNLD-PECKCTDDRLWE 128
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 113 AREKA-LKLLERV---GLSAHANKFPAQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDpeMINE-VLDVMVELANEGM 187
Cdd:cd03288 129 ALEIAqLKNMVKSlpgGLDAVVTEGGENFSVGQRQLFCLARAFVRKSSILIMDEATASID--MATEnILQKVVMTAFADR 206
|
170 180 190
....*....|....*....|....*....|....*..
gi 446554041 188 TMMVVTHEMGFARKvANRVIFMDEGKIIE-DSPKDAF 223
Cdd:cd03288 207 TVVTIAHRVSTILD-ADLVLVLSRGILVEcDTPENLL 242
|
|
| PRK15064 |
PRK15064 |
ABC transporter ATP-binding protein; Provisional |
2-215 |
2.54e-08 |
|
ABC transporter ATP-binding protein; Provisional
Pssm-ID: 237894 [Multi-domain] Cd Length: 530 Bit Score: 53.74 E-value: 2.54e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 2 ITLKNVSKWYGHFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKT-VNGLEPvQQGEItvdgivvndKKTDLAKlrsrVG 80
Cdd:PRK15064 320 LEVENLTKGFDNGPLFKNLNLLLEAGERLAIIGENGVGKTTLLRTlVGELEP-DSGTV---------KWSENAN----IG 385
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 81 MVFQ-HFELFPhlsiiENLTL----AQVKVLKRNkaparEKALK-LLERVGLSA-HANKFPAQLSGGQQQRVAIARALCM 153
Cdd:PRK15064 386 YYAQdHAYDFE-----NDLTLfdwmSQWRQEGDD-----EQAVRgTLGRLLFSQdDIKKSVKVLSGGEKGRMLFGKLMMQ 455
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446554041 154 DPIAMLFDEPTSALDPEMInEVLDVMVELAnEGmTMMVVTHEMGFARKVANRVIFMDEGKII 215
Cdd:PRK15064 456 KPNVLVMDEPTNHMDMESI-ESLNMALEKY-EG-TLIFVSHDREFVSSLATRIIEITPDGVV 514
|
|
| PRK10982 |
PRK10982 |
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional |
137-214 |
2.86e-08 |
|
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
Pssm-ID: 182880 [Multi-domain] Cd Length: 491 Bit Score: 53.58 E-value: 2.86e-08
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446554041 137 LSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLDVMVELANEGMTMMVVTHEMGFARKVANRVIFMDEGKI 214
Cdd:PRK10982 392 LSGGNQQKVIIGRWLLTQPEILMLDEPTRGIDVGAKFEIYQLIAELAKKDKGIIIISSEMPELLGITDRILVMSNGLV 469
|
|
| CFTR_protein |
TIGR01271 |
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ... |
16-169 |
7.32e-08 |
|
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]
Pssm-ID: 273530 [Multi-domain] Cd Length: 1490 Bit Score: 52.61 E-value: 7.32e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 16 VLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQqGEITVDGIVVNdkKTDLAKLRSRVGMVFQHFELFPhlsii 95
Cdd:TIGR01271 1234 VLQDLSFSVEGGQRVGLLGRTGSGKSTLLSALLRLLSTE-GEIQIDGVSWN--SVTLQTWRKAFGVIPQKVFIFS----- 1305
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 96 enltlaqvKVLKRNKAP----AREKALKLLERVGLSAHANKFPAQL-----------SGGQQQRVAIARALCMDPIAMLF 160
Cdd:TIGR01271 1306 --------GTFRKNLDPyeqwSDEEIWKVAEEVGLKSVIEQFPDKLdfvlvdggyvlSNGHKQLMCLARSILSKAKILLL 1377
|
....*....
gi 446554041 161 DEPTSALDP 169
Cdd:TIGR01271 1378 DEPSAHLDP 1386
|
|
| ABC_RNaseL_inhibitor |
cd03222 |
ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a ... |
137-240 |
8.74e-08 |
|
ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins, and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains, which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.
Pssm-ID: 213189 [Multi-domain] Cd Length: 177 Bit Score: 50.65 E-value: 8.74e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 137 LSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLDVMVELANEGM-TMMVVTHEMGFARKVANRVIfmdegkII 215
Cdd:cd03222 72 LSGGELQRVAIAAALLRNATFYLFDEPSAYLDIEQRLNAARAIRRLSEEGKkTALVVEHDLAVLDYLSDRIH------VF 145
|
90 100
....*....|....*....|....*...
gi 446554041 216 EDSP-KDAFFDNPKSDR--AKDFLAKIL 240
Cdd:cd03222 146 EGEPgVYGIASQPKGTRegINRFLRGYL 173
|
|
| 3a01205 |
TIGR00956 |
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other] |
34-195 |
1.24e-07 |
|
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273362 [Multi-domain] Cd Length: 1394 Bit Score: 52.03 E-value: 1.24e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNglEPVQQGEITVDGIVVNDKKTDlAKLRSRVGMVFQHFELFPHLSIIENLT----LAQVK-VLKR 108
Cdd:TIGR00956 796 GASGAGKTTLLNVLA--ERVTTGVITGGDRLVNGRPLD-SSFQRSIGYVQQQDLHLPTSTVRESLRfsayLRQPKsVSKS 872
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 109 NKAPAREKALKLLER-------VGLSAHAnkfpaqLSGGQQQRVAIARALCMDPIAMLF-DEPTSALDPEMINEVLDVMV 180
Cdd:TIGR00956 873 EKMEYVEEVIKLLEMesyadavVGVPGEG------LNVEQRKRLTIGVELVAKPKLLLFlDEPTSGLDSQTAWSICKLMR 946
|
170
....*....|....*
gi 446554041 181 ELANEGMTMMVVTHE 195
Cdd:TIGR00956 947 KLADHGQAILCTIHQ 961
|
|
| PRK13540 |
PRK13540 |
cytochrome c biogenesis protein CcmA; Provisional |
34-195 |
1.24e-07 |
|
cytochrome c biogenesis protein CcmA; Provisional
Pssm-ID: 184127 [Multi-domain] Cd Length: 200 Bit Score: 50.33 E-value: 1.24e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEPVQQGEITVDGivvNDKKTDLAKLRSRVGMVFQHFELFPHLSIIENLTLaqvkvlkrnKAPA 113
Cdd:PRK13540 34 GSNGAGKTTLLKLIAGLLNPEKGEILFER---QSIKKDLCTYQKQLCFVGHRSGINPYLTLRENCLY---------DIHF 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 114 REKALKLLERVGLSA--HANKFP-AQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLDVMVELANEGMTMM 190
Cdd:PRK13540 102 SPGAVGITELCRLFSleHLIDYPcGLLSSGQKRQVALLRLWMSKAKLWLLDEPLVALDELSLLTIITKIQEHRAKGGAVL 181
|
....*
gi 446554041 191 VVTHE 195
Cdd:PRK13540 182 LTSHQ 186
|
|
| PRK10938 |
PRK10938 |
putative molybdenum transport ATP-binding protein ModF; Provisional |
114-214 |
1.33e-07 |
|
putative molybdenum transport ATP-binding protein ModF; Provisional
Pssm-ID: 182852 [Multi-domain] Cd Length: 490 Bit Score: 51.55 E-value: 1.33e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 114 REKALKLLERVGLSAHANKFPAQ-LSGGQQQRVAIARALCMDPIAMLFDEPTSALDP---EMINEVLDVMVelaNEGMT- 188
Cdd:PRK10938 378 QKLAQQWLDILGIDKRTADAPFHsLSWGQQRLALIVRALVKHPTLLILDEPLQGLDPlnrQLVRRFVDVLI---SEGETq 454
|
90 100
....*....|....*....|....*..
gi 446554041 189 MMVVTHEMGFA-RKVANRVIFMDEGKI 214
Cdd:PRK10938 455 LLFVSHHAEDApACITHRLEFVPDGDI 481
|
|
| PLN03130 |
PLN03130 |
ABC transporter C family member; Provisional |
34-219 |
1.35e-07 |
|
ABC transporter C family member; Provisional
Pssm-ID: 215595 [Multi-domain] Cd Length: 1622 Bit Score: 52.05 E-value: 1.35e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVndKKTDLAKLRSRVGMVFQ---------HFELFP---H--LSIIENLT 99
Cdd:PLN03130 1272 GRTGAGKSSMLNALFRIVELERGRILIDGCDI--SKFGLMDLRKVLGIIPQapvlfsgtvRFNLDPfneHndADLWESLE 1349
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 100 LAQVK-VLKRNKaparekalkllerVGLSAHANKFPAQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMinevlDV 178
Cdd:PLN03130 1350 RAHLKdVIRRNS-------------LGLDAEVSEAGENFSVGQRQLLSLARALLRRSKILVLDEATAAVDVRT-----DA 1411
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 446554041 179 MVE--LANE--GMTMMVVTHEMGFARKvANRVIFMDEGKIIE-DSP 219
Cdd:PLN03130 1412 LIQktIREEfkSCTMLIIAHRLNTIID-CDRILVLDAGRVVEfDTP 1456
|
|
| ABC_UvrA_I |
cd03270 |
ATP-binding cassette domain I of the excision repair protein UvrA; Nucleotide excision repair ... |
34-195 |
1.63e-07 |
|
ATP-binding cassette domain I of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins, and UvrB having one ATP binding site that is structurally related to that of helicases.
Pssm-ID: 213237 [Multi-domain] Cd Length: 226 Bit Score: 50.33 E-value: 1.63e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLI----------KTVNGLEPV------QQGEITVDGI------VVNDKKTDLAKLRSRVGMVFqhfELFPH 91
Cdd:cd03270 28 GVSGSGKSSLAfdtiyaegqrRYVESLSAYarqflgQMDKPDVDSIeglspaIAIDQKTTSRNPRSTVGTVT---EIYDY 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 92 LSiienLTLAQVKVLKRnkaparekaLKLLERVGLS-AHANKFPAQLSGGQQQRVAIARALCMDPIAML--FDEPTSALD 168
Cdd:cd03270 105 LR----LLFARVGIRER---------LGFLVDVGLGyLTLSRSAPTLSGGEAQRIRLATQIGSGLTGVLyvLDEPSIGLH 171
|
170 180
....*....|....*....|....*..
gi 446554041 169 PEMINEVLDVMVELANEGMTMMVVTHE 195
Cdd:cd03270 172 PRDNDRLIETLKRLRDLGNTVLVVEHD 198
|
|
| PRK13409 |
PRK13409 |
ribosome biogenesis/translation initiation ATPase RLI; |
34-207 |
1.81e-07 |
|
ribosome biogenesis/translation initiation ATPase RLI;
Pssm-ID: 184037 [Multi-domain] Cd Length: 590 Bit Score: 51.35 E-value: 1.81e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNG-LEPVQqGEITVDgIVVNDK----KTD--------LAKLRSRVGMVFQHFElfphlsIIENLTL 100
Cdd:PRK13409 372 GPNGIGKTTFAKLLAGvLKPDE-GEVDPE-LKISYKpqyiKPDydgtvedlLRSITDDLGSSYYKSE------IIKPLQL 443
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 101 AqvkvlkrnkaparekalKLLER-VGlsahankfpaQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPE---MINEVL 176
Cdd:PRK13409 444 E-----------------RLLDKnVK----------DLSGGELQRVAIAACLSRDADLYLLDEPSAHLDVEqrlAVAKAI 496
|
170 180 190
....*....|....*....|....*....|.
gi 446554041 177 DVMVElaNEGMTMMVVTHEMGFARKVANRVI 207
Cdd:PRK13409 497 RRIAE--EREATALVVDHDIYMIDYISDRLM 525
|
|
| ABCC_SUR1_N |
cd03290 |
ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The ... |
34-212 |
2.03e-07 |
|
ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The sulfonylurea receptor SUR is an ATP transporter of the ABCC/MRP family with tandem ATPase binding domains. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.
Pssm-ID: 213257 [Multi-domain] Cd Length: 218 Bit Score: 50.02 E-value: 2.03e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVNDKKTDLAKLRSR--VGMVFQHFELFpHLSIIENLTLAQVKVLKRNKA 111
Cdd:cd03290 34 GQVGCGKSSLLLAILGEMQTLEGKVHWSNKNESEPSFEATRSRNRysVAYAAQKPWLL-NATVEENITFGSPFNKQRYKA 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 112 PAreKALKLLERVGLSAHANKFPA-----QLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLD--VMVELAN 184
Cdd:cd03290 113 VT--DACSLQPDIDLLPFGDQTEIgergiNLSGGQRQRICVARALYQNTNIVFLDDPFSALDIHLSDHLMQegILKFLQD 190
|
170 180
....*....|....*....|....*...
gi 446554041 185 EGMTMMVVTHEMGFARKvANRVIFMDEG 212
Cdd:cd03290 191 DKRTLVLVTHKLQYLPH-ADWIIAMKDG 217
|
|
| ABC_ABC_ChvD |
TIGR03719 |
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ... |
2-214 |
2.65e-07 |
|
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.
Pssm-ID: 274744 [Multi-domain] Cd Length: 552 Bit Score: 50.70 E-value: 2.65e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 2 ITLKNVSKWYGHFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQQGEI----TVDGIVVNDKKTDLAKLRS 77
Cdd:TIGR03719 323 IEAENLTKAFGDKLLIDDLSFKLPPGGIVGVIGPNGAGKSTLFRMITGQEQPDSGTIeigeTVKLAYVDQSRDALDPNKT 402
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 78 rvgmVFQhfELFPHLSIIEnltLAQVKVLKRN-------KAPAREKalklleRVGlsahankfpaQLSGGQQQRVAIARA 150
Cdd:TIGR03719 403 ----VWE--EISGGLDIIK---LGKREIPSRAyvgrfnfKGSDQQK------KVG----------QLSGGERNRVHLAKT 457
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446554041 151 LCMDPIAMLFDEPTSALDPEMINEVLDVMVELANegmTMMVVTHEMGFARKVANRVI-FMDEGKI 214
Cdd:TIGR03719 458 LKSGGNVLLLDEPTNDLDVETLRALEEALLNFAG---CAVVISHDRWFLDRIATHILaFEGDSHV 519
|
|
| ABC_Class2 |
cd03227 |
ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems ... |
34-194 |
3.09e-07 |
|
ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems involved in cellular processes other than transport. These families are characterized by the fact that the ABC subunit is made up of duplicated, fused ABC modules (ABC2). No known transmembrane proteins or domains are associated with these proteins.
Pssm-ID: 213194 [Multi-domain] Cd Length: 162 Bit Score: 48.90 E-value: 3.09e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKtvnglepvqqgeitvdgivvndkktdlaklrsrvgmvfqhfelfphlSIIENLTLAQVKVLKRNKAPA 113
Cdd:cd03227 28 GPNGSGKSTILD-----------------------------------------------AIGLALGGAQSATRRRSGVKA 60
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 114 RE-KALKLLERVGLSAhankfpaQLSGGQQQRVAIARAL----CMDPIAMLFDEPTSALDPEMINEVLDVMVELANEGMT 188
Cdd:cd03227 61 GCiVAAVSAELIFTRL-------QLSGGEKELSALALILalasLKPRPLYILDEIDRGLDPRDGQALAEAILEHLVKGAQ 133
|
....*.
gi 446554041 189 MMVVTH 194
Cdd:cd03227 134 VIVITH 139
|
|
| PLN03232 |
PLN03232 |
ABC transporter C family member; Provisional |
34-221 |
4.75e-07 |
|
ABC transporter C family member; Provisional
Pssm-ID: 215640 [Multi-domain] Cd Length: 1495 Bit Score: 50.36 E-value: 4.75e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVndKKTDLAKLRSRVGMVFQHFELFP--------------HLSIIENLT 99
Cdd:PLN03232 1269 GRTGAGKSSMLNALFRIVELEKGRIMIDDCDV--AKFGLTDLRRVLSIIPQSPVLFSgtvrfnidpfsehnDADLWEALE 1346
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 100 LAQVK-VLKRNKaparekalkllerVGLSAHANKFPAQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEmINEVLDV 178
Cdd:PLN03232 1347 RAHIKdVIDRNP-------------FGLDAEVSEGGENFSVGQRQLLSLARALLRRSKILVLDEATASVDVR-TDSLIQR 1412
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 446554041 179 MVELANEGMTMMVVTHEMGFARKvANRVIFMDEGKIIE-DSPKD 221
Cdd:PLN03232 1413 TIREEFKSCTMLVIAHRLNTIID-CDKILVLSSGQVLEyDSPQE 1455
|
|
| PRK00635 |
PRK00635 |
excinuclease ABC subunit A; Provisional |
87-233 |
9.19e-07 |
|
excinuclease ABC subunit A; Provisional
Pssm-ID: 234806 [Multi-domain] Cd Length: 1809 Bit Score: 49.44 E-value: 9.19e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 87 ELFPHLSIIENLTLAQVKVLKRNKAparekALKLLERVGLS-AHANKFPAQLSGGQQQRVAIARALC--MDPIAMLFDEP 163
Cdd:PRK00635 431 ELFIFLSQLPSKSLSIEEVLQGLKS-----RLSILIDLGLPyLTPERALATLSGGEQERTALAKHLGaeLIGITYILDEP 505
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446554041 164 TSALDPEMINEVLDVMVELANEGMTMMVVTHEMGFArKVANRVIFMDEGKII-------EDSPKDaFFDNPKSDRAK 233
Cdd:PRK00635 506 SIGLHPQDTHKLINVIKKLRDQGNTVLLVEHDEQMI-SLADRIIDIGPGAGIfggevlfNGSPRE-FLAKSDSLTAK 580
|
|
| PRK11819 |
PRK11819 |
putative ABC transporter ATP-binding protein; Reviewed |
34-215 |
9.44e-07 |
|
putative ABC transporter ATP-binding protein; Reviewed
Pssm-ID: 236992 [Multi-domain] Cd Length: 556 Bit Score: 48.96 E-value: 9.44e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEPVQQGEITV-DGIvvndkktdlaklrsRVGMVFQHFELFPHLSIIENLTLA---QVKVLKR- 108
Cdd:PRK11819 40 GLNGAGKSTLLRIMAGVDKEFEGEARPaPGI--------------KVGYLPQEPQLDPEKTVRENVEEGvaeVKAALDRf 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 109 ---NKAPAREKAL--KLLERVG-------------------LSAHANKFP------AQLSGGQQQRVAIARALCMDPIAM 158
Cdd:PRK11819 106 neiYAAYAEPDADfdALAAEQGelqeiidaadawdldsqleIAMDALRCPpwdakvTKLSGGERRRVALCRLLLEKPDML 185
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 446554041 159 LFDEPTSALDPEMINevldvMVE--LANEGMTMMVVTHEMGFARKVANRVIFMDEGKII 215
Cdd:PRK11819 186 LLDEPTNHLDAESVA-----WLEqfLHDYPGTVVAVTHDRYFLDNVAGWILELDRGRGI 239
|
|
| SbcC |
COG0419 |
DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]; |
33-194 |
2.51e-06 |
|
DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair];
Pssm-ID: 440188 [Multi-domain] Cd Length: 204 Bit Score: 46.54 E-value: 2.51e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 33 CGPSGSGKSTL---IKTVNGLEPVQQGEITVDGIVVNDKKTdlaklrsRVGMVFQH-------------FELFPHLS--- 93
Cdd:COG0419 29 VGPNGAGKSTIleaIRYALYGKARSRSKLRSDLINVGSEEA-------SVELEFEHggkryrierrqgeFAEFLEAKpse 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 94 ---IIENLTLAQV-----KVLKRNKAPAREKALKLLERVGLSAH-ANKF-----PAQLSGGQQQRVAIARALcmdpiAML 159
Cdd:COG0419 102 rkeALKRLLGLEIyeelkERLKELEEALESALEELAELQKLKQEiLAQLsgldpIETLSGGERLRLALADLL-----SLI 176
|
170 180 190
....*....|....*....|....*....|....*
gi 446554041 160 FDepTSALDPEMINEVLDVMVELAnegmtmmVVTH 194
Cdd:COG0419 177 LD--FGSLDEERLERLLDALEELA-------IITH 202
|
|
| uvra |
TIGR00630 |
excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of ... |
112-207 |
2.91e-06 |
|
excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of proteins of which all members for which functions are known except the UvrA proteins are involved in the transport of material through membranes. UvrA orthologs are involved in the recognition of DNA damage as a step in nucleotide excision repair. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273184 [Multi-domain] Cd Length: 925 Bit Score: 47.70 E-value: 2.91e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 112 PAREKALKLLERVGLSAHANKFPA-QLSGGQQQRVAIARAL---CMDPIAMLFDEPTSALDPEMINEVLDVMVELANEGM 187
Cdd:TIGR00630 804 PSISRKLQTLCDVGLGYIRLGQPAtTLSGGEAQRIKLAKELskrSTGRTLYILDEPTTGLHFDDIKKLLEVLQRLVDKGN 883
|
90 100
....*....|....*....|
gi 446554041 188 TMMVVTHEMGFArKVANRVI 207
Cdd:TIGR00630 884 TVVVIEHNLDVI-KTADYII 902
|
|
| ABC_UvrA_II |
cd03271 |
ATP-binding cassette domain II of the excision repair protein UvrA; Nucleotide excision repair ... |
118-207 |
2.93e-06 |
|
ATP-binding cassette domain II of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins and UvrB having one ATP binding site that is structurally related to that of helicases.
Pssm-ID: 213238 [Multi-domain] Cd Length: 261 Bit Score: 46.84 E-value: 2.93e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 118 LKLLERVGLSAHANKFPA-QLSGGQQQRVAIARALCM---DPIAMLFDEPTSALDPEMINEVLDVMVELANEGMTMMVVT 193
Cdd:cd03271 150 LQTLCDVGLGYIKLGQPAtTLSGGEAQRIKLAKELSKrstGKTLYILDEPTTGLHFHDVKKLLEVLQRLVDKGNTVVVIE 229
|
90
....*....|....
gi 446554041 194 HEMGFArKVANRVI 207
Cdd:cd03271 230 HNLDVI-KCADWII 242
|
|
| Rli1 |
COG1245 |
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ... |
137-207 |
4.32e-06 |
|
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];
Pssm-ID: 440858 [Multi-domain] Cd Length: 592 Bit Score: 47.09 E-value: 4.32e-06
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446554041 137 LSGGQQQRVAIARALCMDPIAMLFDEPTSALDPE---MINEVLDVMVElaNEGMTMMVVTHEMGFARKVANRVI 207
Cdd:COG1245 456 LSGGELQRVAIAACLSRDADLYLLDEPSAHLDVEqrlAVAKAIRRFAE--NRGKTAMVVDHDIYLIDYISDRLM 527
|
|
| PLN03073 |
PLN03073 |
ABC transporter F family; Provisional |
136-215 |
4.63e-06 |
|
ABC transporter F family; Provisional
Pssm-ID: 215558 [Multi-domain] Cd Length: 718 Bit Score: 47.16 E-value: 4.63e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 136 QLSGGQQQRVAIARALCMDPIAMLFDEPTSALDpemINEVLDVMVELANEGMTMMVVTHEMGFARKVANRVIFMDEGKII 215
Cdd:PLN03073 344 TFSGGWRMRIALARALFIEPDLLLLDEPTNHLD---LHAVLWLETYLLKWPKTFIVVSHAREFLNTVVTDILHLHGQKLV 420
|
|
| PRK10636 |
PRK10636 |
putative ABC transporter ATP-binding protein; Provisional |
34-214 |
1.53e-05 |
|
putative ABC transporter ATP-binding protein; Provisional
Pssm-ID: 236729 [Multi-domain] Cd Length: 638 Bit Score: 45.55 E-value: 1.53e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNG-LEPvQQGEITvdgivvndkktdLAKlRSRVGMVFQHfelfphlsiienltlaQVKVLKRNKAP 112
Cdd:PRK10636 345 GRNGAGKSTLIKLLAGeLAP-VSGEIG------------LAK-GIKLGYFAQH----------------QLEFLRADESP 394
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 113 --------AREKALKLLERVG-LSAHANKFP---AQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLDVMV 180
Cdd:PRK10636 395 lqhlarlaPQELEQKLRDYLGgFGFQGDKVTeetRRFSGGEKARLVLALIVWQRPNLLLLDEPTNHLDLDMRQALTEALI 474
|
170 180 190
....*....|....*....|....*....|....
gi 446554041 181 ELanEGmTMMVVTHEMGFARKVANRVIFMDEGKI 214
Cdd:PRK10636 475 DF--EG-ALVVVSHDRHLLRSTTDDLYLVHDGKV 505
|
|
| GguA |
NF040905 |
sugar ABC transporter ATP-binding protein; |
137-221 |
2.53e-05 |
|
sugar ABC transporter ATP-binding protein;
Pssm-ID: 468840 [Multi-domain] Cd Length: 500 Bit Score: 44.78 E-value: 2.53e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 137 LSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLDVMVELANEGMTMMVVTHEMGFARKVANRVIFMDEGKIIE 216
Cdd:NF040905 405 LSGGNQQKVVLSKWLFTDPDVLILDEPTRGIDVGAKYEIYTIINELAAEGKGVIVISSELPELLGMCDRIYVMNEGRITG 484
|
....*
gi 446554041 217 DSPKD 221
Cdd:NF040905 485 ELPRE 489
|
|
| CFTR_protein |
TIGR01271 |
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ... |
16-212 |
2.96e-05 |
|
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]
Pssm-ID: 273530 [Multi-domain] Cd Length: 1490 Bit Score: 44.90 E-value: 2.96e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 16 VLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNG-LEPvQQGEITVDGivvndkktdlaklrsRVGMVFQHFELFPHlSI 94
Cdd:TIGR01271 441 VLKNISFKLEKGQLLAVAGSTGSGKSSLLMMIMGeLEP-SEGKIKHSG---------------RISFSPQTSWIMPG-TI 503
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 95 IENLTLAQVKVLKRNKAPAreKALKLLERVGLSAHANKFP-----AQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDP 169
Cdd:TIGR01271 504 KDNIIFGLSYDEYRYTSVI--KACQLEEDIALFPEKDKTVlgeggITLSGGQRARISLARAVYKDADLYLLDSPFTHLDV 581
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 446554041 170 EMINEVLDVMVELANEGMTMMVVTHEMGFARKvANRVIFMDEG 212
Cdd:TIGR01271 582 VTEKEIFESCLCKLMSNKTRILVTSKLEHLKK-ADKILLLHEG 623
|
|
| ABC_Rad50 |
cd03240 |
ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ... |
134-195 |
2.98e-05 |
|
ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ATP-binding cassette of ABC transporters, but are not associated with membrane-spanning domains. The conserved ATP-binding motifs common to Rad50 and the ABC transporter family include the Walker A and Walker B motifs, the Q loop, a histidine residue in the switch region, a D-loop, and a conserved LSGG sequence. This conserved sequence, LSGG, is the most specific and characteristic motif of this family and is thus known as the ABC signature sequence.
Pssm-ID: 213207 [Multi-domain] Cd Length: 204 Bit Score: 43.75 E-value: 2.98e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446554041 134 PAQLSGGQQQ------RVAIARALC--MDPIAMlfDEPTSALDPEMINEVLDVMVELANE--GMTMMVVTHE 195
Cdd:cd03240 113 RGRCSGGEKVlasliiRLALAETFGsnCGILAL--DEPTTNLDEENIEESLAEIIEERKSqkNFQLIVITHD 182
|
|
| PRK11819 |
PRK11819 |
putative ABC transporter ATP-binding protein; Reviewed |
34-170 |
3.64e-05 |
|
putative ABC transporter ATP-binding protein; Reviewed
Pssm-ID: 236992 [Multi-domain] Cd Length: 556 Bit Score: 44.34 E-value: 3.64e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEPVQQGEITV-------------DGIvvNDKKTdlaklrsrvgmVFQhfELFPHLSIIEnltL 100
Cdd:PRK11819 357 GPNGAGKSTLFKMITGQEQPDSGTIKIgetvklayvdqsrDAL--DPNKT-----------VWE--EISGGLDIIK---V 418
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446554041 101 AQVKVLKR------N-KAPAREKalklleRVGlsahankfpaQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPE 170
Cdd:PRK11819 419 GNREIPSRayvgrfNfKGGDQQK------KVG----------VLSGGERNRLHLAKTLKQGGNVLLLDEPTNDLDVE 479
|
|
| PTZ00243 |
PTZ00243 |
ABC transporter; Provisional |
34-214 |
4.01e-05 |
|
ABC transporter; Provisional
Pssm-ID: 240327 [Multi-domain] Cd Length: 1560 Bit Score: 44.38 E-value: 4.01e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEPVQQGEITVDgivvndkktdlaklRSrvgmvfqhFELFPHLSIIENLTLAQVKVLKRNKAPA 113
Cdd:PTZ00243 693 GATGSGKSTLLQSLLSQFEISEGRVWAE--------------RS--------IAYVPQQAWIMNATVRGNILFFDEEDAA 750
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 114 R----------EKALKLLERvGLSAHANKFPAQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLDVMVELA 183
Cdd:PTZ00243 751 RladavrvsqlEADLAQLGG-GLETEIGEKGVNLSGGQKARVSLARAVYANRDVYLLDDPLSALDAHVGERVVEECFLGA 829
|
170 180 190
....*....|....*....|....*....|.
gi 446554041 184 NEGMTMMVVTHEMGFARKvANRVIFMDEGKI 214
Cdd:PTZ00243 830 LAGKTRVLATHQVHVVPR-ADYVVALGDGRV 859
|
|
| ABCC_CFTR1 |
cd03291 |
ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The ... |
34-212 |
4.86e-05 |
|
ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The CFTR subfamily domain 1. The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits, or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.
Pssm-ID: 213258 [Multi-domain] Cd Length: 282 Bit Score: 43.31 E-value: 4.86e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNG-LEPvQQGEITVDGivvndkktdlaklrsRVGMVFQHFELFPHlSIIENLTLAQVKVLKRNKAP 112
Cdd:cd03291 70 GSTGSGKTSLLMLILGeLEP-SEGKIKHSG---------------RISFSSQFSWIMPG-TIKENIIFGVSYDEYRYKSV 132
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 113 AreKALKLLERVglsahaNKFPAQ-----------LSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLDVMV- 180
Cdd:cd03291 133 V--KACQLEEDI------TKFPEKdntvlgeggitLSGGQRARISLARAVYKDADLYLLDSPFGYLDVFTEKEIFESCVc 204
|
170 180 190
....*....|....*....|....*....|...
gi 446554041 181 -ELANEgmTMMVVTHEMGFARKvANRVIFMDEG 212
Cdd:cd03291 205 kLMANK--TRILVTSKMEHLKK-ADKILILHEG 234
|
|
| sufC |
PRK09580 |
cysteine desulfurase ATPase component; Reviewed |
34-194 |
6.94e-05 |
|
cysteine desulfurase ATPase component; Reviewed
Pssm-ID: 181965 [Multi-domain] Cd Length: 248 Bit Score: 42.86 E-value: 6.94e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEpvqqgEITVDGIVVNDKKTDLAKL--RSRVG----MVFQHFELFPHLSIIENLTLAQVKVLK 107
Cdd:PRK09580 34 GPNGSGKSTLSATLAGRE-----DYEVTGGTVEFKGKDLLELspEDRAGegifMAFQYPVEIPGVSNQFFLQTALNAVRS 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 108 -RNKAPAR--------EKALKLLervglsahanKFPAQL---------SGGQQQRVAIARALCMDPIAMLFDEPTSALDP 169
Cdd:PRK09580 109 yRGQEPLDrfdfqdlmEEKIALL----------KMPEDLltrsvnvgfSGGEKKRNDILQMAVLEPELCILDESDSGLDI 178
|
170 180
....*....|....*....|....*
gi 446554041 170 EMINEVLDVMVELANEGMTMMVVTH 194
Cdd:PRK09580 179 DALKIVADGVNSLRDGKRSFIIVTH 203
|
|
| PTZ00243 |
PTZ00243 |
ABC transporter; Provisional |
34-221 |
1.08e-04 |
|
ABC transporter; Provisional
Pssm-ID: 240327 [Multi-domain] Cd Length: 1560 Bit Score: 43.23 E-value: 1.08e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVNdkKTDLAKLRSRVGMVFQHFELFphlsiieNLTLAQvkvlkrNKAPA 113
Cdd:PTZ00243 1343 GRTGSGKSTLLLTFMRMVEVCGGEIRVNGREIG--AYGLRELRRQFSMIPQDPVLF-------DGTVRQ------NVDPF 1407
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 114 RE-------KALKLL---ERV-----GLSAHANKFPAQLSGGQQQRVAIARALCMDPIA-MLFDEPTSALDPEMINEV-L 176
Cdd:PTZ00243 1408 LEassaevwAALELVglrERVaseseGIDSRVLEGGSNYSVGQRQLMCMARALLKKGSGfILMDEATANIDPALDRQIqA 1487
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 446554041 177 DVMVELANegMTMMVVTHEMgfaRKVA--NRVIFMDEGKIIE-DSPKD 221
Cdd:PTZ00243 1488 TVMSAFSA--YTVITIAHRL---HTVAqyDKIIVMDHGAVAEmGSPRE 1530
|
|
| PLN03073 |
PLN03073 |
ABC transporter F family; Provisional |
34-195 |
1.21e-04 |
|
ABC transporter F family; Provisional
Pssm-ID: 215558 [Multi-domain] Cd Length: 718 Bit Score: 42.92 E-value: 1.21e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNG-LEPVQqgeitvdGIVVNDKKTdlaklrsRVGMVFQHFelfphlsiIENLTLAQVKVL--KRNK 110
Cdd:PLN03073 542 GPNGIGKSTILKLISGeLQPSS-------GTVFRSAKV-------RMAVFSQHH--------VDGLDLSSNPLLymMRCF 599
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 111 APAREKALKL-LERVGLSAHANKFPA-QLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLDVMVeLANEGMT 188
Cdd:PLN03073 600 PGVPEQKLRAhLGSFGVTGNLALQPMyTLSGGQKSRVAFAKITFKKPHILLLDEPSNHLDLDAVEALIQGLV-LFQGGVL 678
|
....*..
gi 446554041 189 MmvVTHE 195
Cdd:PLN03073 679 M--VSHD 683
|
|
| PRK00635 |
PRK00635 |
excinuclease ABC subunit A; Provisional |
137-207 |
1.24e-04 |
|
excinuclease ABC subunit A; Provisional
Pssm-ID: 234806 [Multi-domain] Cd Length: 1809 Bit Score: 42.89 E-value: 1.24e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446554041 137 LSGGQQQRVAIARALCM---DPIAMLFDEPTSALDPEMINEVLDVMVELANEGMTMMVVTHEMGFArKVANRVI 207
Cdd:PRK00635 810 LSGGEIQRLKLAYELLApskKPTLYVLDEPTTGLHTHDIKALIYVLQSLTHQGHTVVIIEHNMHVV-KVADYVL 882
|
|
| AAA_21 |
pfam13304 |
AAA domain, putative AbiEii toxin, Type IV TA system; Several members are annotated as being ... |
71-194 |
1.42e-04 |
|
AAA domain, putative AbiEii toxin, Type IV TA system; Several members are annotated as being of the abortive phage resistance system, in which case the family would be acting as the toxin for a type IV toxin-antitoxin resistance system.
Pssm-ID: 433102 [Multi-domain] Cd Length: 303 Bit Score: 41.99 E-value: 1.42e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 71 DLAKLRSRVGMVFQHFELFPHLSIIENLTLAQVKVLKRNKAPAREKALKLLERvglsAHANKFPA-QLSGGQQQ---RVA 146
Cdd:pfam13304 174 DLALFPDLKELLQRLVRGLKLADLNLSDLGEGIEKSLLVDDRLRERGLILLEN----GGGGELPAfELSDGTKRllaLLA 249
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 446554041 147 IARALCMDPIAMLFDEPTSALDPEMINEVLDVMVELANEGMTMMVVTH 194
Cdd:pfam13304 250 ALLSALPKGGLLLIDEPESGLHPKLLRRLLELLKELSRNGAQLILTTH 297
|
|
| PRK13546 |
PRK13546 |
teichoic acids export ABC transporter ATP-binding subunit TagH; |
34-221 |
1.59e-04 |
|
teichoic acids export ABC transporter ATP-binding subunit TagH;
Pssm-ID: 184131 [Multi-domain] Cd Length: 264 Bit Score: 41.73 E-value: 1.59e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEPVQQGEITVDGivvndkktdlaklrsRVGMVFQHFELFPHLSIIENLtlaQVKVLKRNKAPA 113
Cdd:PRK13546 57 GINGSGKSTLSNIIGGSLSPTVGKVDRNG---------------EVSVIAISAGLSGQLTGIENI---EFKMLCMGFKRK 118
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 114 REKAL--KLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLDVMVELANEGMTMMV 191
Cdd:PRK13546 119 EIKAMtpKIIEFSELGEFIYQPVKKYSSGMRAKLGFSINITVNPDILVIDEALSVGDQTFAQKCLDKIYEFKEQNKTIFF 198
|
170 180 190
....*....|....*....|....*....|
gi 446554041 192 VTHEMGFARKVANRVIFMDEGKIIEDSPKD 221
Cdd:PRK13546 199 VSHNLGQVRQFCTKIAWIEGGKLKDYGELD 228
|
|
| PRK11147 |
PRK11147 |
ABC transporter ATPase component; Reviewed |
34-214 |
2.50e-04 |
|
ABC transporter ATPase component; Reviewed
Pssm-ID: 236861 [Multi-domain] Cd Length: 635 Bit Score: 41.86 E-value: 2.50e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNG-LEPvQQGEITVDgivvndKKTDLAklrsrvgmVF-QH-FELFPHLSIIENLtlAQVK------ 104
Cdd:PRK11147 352 GPNGCGKTTLLKLMLGqLQA-DSGRIHCG------TKLEVA--------YFdQHrAELDPEKTVMDNL--AEGKqevmvn 414
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 105 -----VL----------KRNKAPAreKALkllervglsahankfpaqlSGGQQQRVAIARaLCMDPIAML-FDEPTSALD 168
Cdd:PRK11147 415 grprhVLgylqdflfhpKRAMTPV--KAL-------------------SGGERNRLLLAR-LFLKPSNLLiLDEPTNDLD 472
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 446554041 169 PEMInEVLDVMveLANEGMTMMVVTHEMGFarkVANRV----IFMDEGKI 214
Cdd:PRK11147 473 VETL-ELLEEL--LDSYQGTVLLVSHDRQF---VDNTVtecwIFEGNGKI 516
|
|
| PRK10938 |
PRK10938 |
putative molybdenum transport ATP-binding protein ModF; Provisional |
34-192 |
3.10e-04 |
|
putative molybdenum transport ATP-binding protein ModF; Provisional
Pssm-ID: 182852 [Multi-domain] Cd Length: 490 Bit Score: 41.54 E-value: 3.10e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEPVQQGEITVD--GIVvndkKTDLAKLRSRVGMVFQH--FELfphLSIIEN---LTLAQVkVL 106
Cdd:PRK10938 36 GANGSGKSALARALAGELPLLSGERQSQfsHIT----RLSFEQLQKLVSDEWQRnnTDM---LSPGEDdtgRTTAEI-IQ 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 107 KRNKAPARekALKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLDVMVELANEG 186
Cdd:PRK10938 108 DEVKDPAR--CEQLAQQFGITALLDRRFKYLSTGETRKTLLCQALMSEPDLLILDEPFDGLDVASRQQLAELLASLHQSG 185
|
....*.
gi 446554041 187 MTMMVV 192
Cdd:PRK10938 186 ITLVLV 191
|
|
| tagH |
PRK13545 |
teichoic acids export protein ATP-binding subunit; Provisional |
34-216 |
3.82e-04 |
|
teichoic acids export protein ATP-binding subunit; Provisional
Pssm-ID: 184130 [Multi-domain] Cd Length: 549 Bit Score: 41.03 E-value: 3.82e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 34 GPSGSGKSTLIKTVNGLEPVQQGEITVDGivvndkKTDLAKLRSrvgmvfqhfELFPHLSIIENLTLAQVkVLKRNKAPA 113
Cdd:PRK13545 57 GLNGSGKSTLSNLIAGVTMPNKGTVDIKG------SAALIAISS---------GLNGQLTGIENIELKGL-MMGLTKEKI 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 114 REKALKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEMINEVLDVMVELANEGMTMMVVT 193
Cdd:PRK13545 121 KEIIPEIIEFADIGKFIYQPVKTYSSGMKSRLGFAISVHINPDILVIDEALSVGDQTFTKKCLDKMNEFKEQGKTIFFIS 200
|
170 180
....*....|....*....|...
gi 446554041 194 HEMGFARKVANRVIFMDEGKIIE 216
Cdd:PRK13545 201 HSLSQVKSFCTKALWLHYGQVKE 223
|
|
| AAA |
smart00382 |
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ... |
33-208 |
7.44e-04 |
|
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.
Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 38.89 E-value: 7.44e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 33 CGPSGSGKSTLIKTV-NGLEPVQQGEITVDGivvndkktdlaklrsrvgmvfqhfelfphlsiienltlaqvkvlkrnka 111
Cdd:smart00382 8 VGPPGSGKTTLARALaRELGPPGGGVIYIDG------------------------------------------------- 38
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 112 parEKALKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMDPIAMLFDEPTSALDPEM------INEVLDVMVELANE 185
Cdd:smart00382 39 ---EDILEEVLDQLLLIIVGGKKASGSGELRLRLALALARKLKPDVLILDEITSLLDAEQeallllLEELRLLLLLKSEK 115
|
170 180
....*....|....*....|...
gi 446554041 186 GMTMMVVTHEMGFARKVANRVIF 208
Cdd:smart00382 116 NLTVILTTNDEKDLGPALLRRRF 138
|
|
| UvrA |
COG0178 |
Excinuclease UvrABC ATPase subunit [Replication, recombination and repair]; |
118-196 |
9.00e-04 |
|
Excinuclease UvrABC ATPase subunit [Replication, recombination and repair];
Pssm-ID: 439948 [Multi-domain] Cd Length: 941 Bit Score: 40.01 E-value: 9.00e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 118 LKLLERVGL-------SAhankfpAQLSGGQQQRVAIARALcmdpiAM--------LFDEPTSALDPEMINEVLDVMVEL 182
Cdd:COG0178 807 LQTLQDVGLgyiklgqPA------TTLSGGEAQRVKLASEL-----SKrstgktlyILDEPTTGLHFHDIRKLLEVLHRL 875
|
90
....*....|....
gi 446554041 183 ANEGMTMMVVTHEM 196
Cdd:COG0178 876 VDKGNTVVVIEHNL 889
|
|
| ABC_SMC3_euk |
cd03272 |
ATP-binding cassette domain of eukaryotic SMC3 proteins; The structural maintenance of ... |
136-185 |
1.59e-03 |
|
ATP-binding cassette domain of eukaryotic SMC3 proteins; The structural maintenance of chromosomes (SMC) proteins are large (approximately 110 to 170 kDa), and each is arranged into five recognizable domains. Amino-acid sequence homology of SMC proteins between species is largely confined to the amino- and carboxy-terminal globular domains. The amino-terminal domain contains a 'Walker A' nucleotide-binding domain (GxxGxGKS/T, in the single-letter amino-acid code), which by mutational studies has been shown to be essential in several proteins. The carboxy-terminal domain contains a sequence (the DA-box) that resembles a 'Walker B' motif, and a motif with homology to the signature sequence of the ATP-binding cassette (ABC) family of ATPases. The sequence homology within the carboxy-terminal domain is relatively high within the SMC1-SMC4 group, whereas SMC5 and SMC6 show some divergence in both of these sequences. In eukaryotic cells, the proteins are found as heterodimers of SMC1 paired with SMC3, SMC2 with SMC4, and SMC5 with SMC6 (formerly known as Rad18).
Pssm-ID: 213239 [Multi-domain] Cd Length: 243 Bit Score: 38.78 E-value: 1.59e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....
gi 446554041 136 QLSGGQQQRVAIARALCM---DPIAM-LFDEPTSALDPEMINEVLDVMVELANE 185
Cdd:cd03272 158 QLSGGQKSLVALALIFAIqkcDPAPFyLFDEIDAALDAQYRTAVANMIKELSDG 211
|
|
| PRK10636 |
PRK10636 |
putative ABC transporter ATP-binding protein; Provisional |
114-216 |
1.87e-03 |
|
putative ABC transporter ATP-binding protein; Provisional
Pssm-ID: 236729 [Multi-domain] Cd Length: 638 Bit Score: 39.00 E-value: 1.87e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 114 REKALKLLERVGLSAHANKFPAQ-LSGGQQQRVAIARALCMDPIAMLFDEPTSALDpemINEVLDVMVELANEGMTMMVV 192
Cdd:PRK10636 126 RSRAASLLHGLGFSNEQLERPVSdFSGGWRMRLNLAQALICRSDLLLLDEPTNHLD---LDAVIWLEKWLKSYQGTLILI 202
|
90 100
....*....|....*....|....
gi 446554041 193 THEMGFARKVANRVIFMDEGKIIE 216
Cdd:PRK10636 203 SHDRDFLDPIVDKIIHIEQQSLFE 226
|
|
| PRK15064 |
PRK15064 |
ABC transporter ATP-binding protein; Provisional |
144-214 |
2.05e-03 |
|
ABC transporter ATP-binding protein; Provisional
Pssm-ID: 237894 [Multi-domain] Cd Length: 530 Bit Score: 38.72 E-value: 2.05e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446554041 144 RVAIARALCMDPIAMLFDEPTSALDPEMINEVLDVmveLANEGMTMMVVTHEMGFARKVANRVIFMDEGKI 214
Cdd:PRK15064 163 RVLLAQALFSNPDILLLDEPTNNLDINTIRWLEDV---LNERNSTMIIISHDRHFLNSVCTHMADLDYGEL 230
|
|
| uvra |
TIGR00630 |
excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of ... |
118-229 |
5.61e-03 |
|
excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of proteins of which all members for which functions are known except the UvrA proteins are involved in the transport of material through membranes. UvrA orthologs are involved in the recognition of DNA damage as a step in nucleotide excision repair. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273184 [Multi-domain] Cd Length: 925 Bit Score: 37.69 E-value: 5.61e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 118 LKLLERVGLS-AHANKFPAQLSGGQQQRVAIARALCMDPIAMLF--DEPTSALDPEMINEVLDVMVELANEGMTMMVVTH 194
Cdd:TIGR00630 469 LGFLIDVGLDyLSLSRAAGTLSGGEAQRIRLATQIGSGLTGVLYvlDEPSIGLHQRDNRRLINTLKRLRDLGNTLIVVEH 548
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 446554041 195 EMGfARKVANRVIFMDEGK-------IIEDSPKDaFFDNPKS 229
Cdd:TIGR00630 549 DED-TIRAADYVIDIGPGAgehggevVASGTPEE-ILANPDS 588
|
|
| uvrA |
PRK00349 |
excinuclease ABC subunit UvrA; |
109-194 |
6.68e-03 |
|
excinuclease ABC subunit UvrA;
Pssm-ID: 234734 [Multi-domain] Cd Length: 943 Bit Score: 37.36 E-value: 6.68e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446554041 109 NKAPAREKaLKLLERVGL-------SAhankfpAQLSGGQQQRVAIA---------RALcmdpiaMLFDEPTSALDPEMI 172
Cdd:PRK00349 803 AIPKIARK-LQTLVDVGLgyiklgqPA------TTLSGGEAQRVKLAkelskrstgKTL------YILDEPTTGLHFEDI 869
|
90 100
....*....|....*....|..
gi 446554041 173 NEVLDVMVELANEGMTMMVVTH 194
Cdd:PRK00349 870 RKLLEVLHRLVDKGNTVVVIEH 891
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
144-202 |
7.80e-03 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 37.33 E-value: 7.80e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446554041 144 RVAIARALCMDPIAMLFDEPTSALDPEMINEVLDVMVELANE-----GMTMMVVTHEMGFARKV 202
Cdd:TIGR00606 1213 RLALAETFCLNCGIIALDEPTTNLDRENIESLAHALVEIIKSrsqqrNFQLLVITHDEDFVELL 1276
|
|
| |
