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Conserved domains on  [gi|446548305|ref|WP_000625651|]
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MULTISPECIES: cell division protein FtsL [Bacteria]

Protein Classification

cell division protein FtsL( domain architecture ID 10013639)

cell division protein FtsL is an essential cell division protein that may link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic

Gene Ontology:  GO:0043093|GO:0032153

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
PRK10772 PRK10772
cell division protein FtsL; Provisional
17-121 1.65e-67

cell division protein FtsL; Provisional


:

Pssm-ID: 182717  Cd Length: 108  Bit Score: 198.42  E-value: 1.65e-67
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446548305  17 GSNERHALPGVIGDDLLRFGKLPLCLFICIILTAVTVVTTAHHTRLLTAQREQLVLERDALDIEWRNLILEENALGDHSR 96
Cdd:PRK10772   4 GSNERHALPGVIGDDLLRNGKLPLCLFIAVIVSAVTVVTTAHHTRLLTAEREQLVLERDALDIEWRNLILEENALGDHSR 83
                         90       100
                 ....*....|....*....|....*
gi 446548305  97 VERIATEKLQMQHVDPSQENIVVQK 121
Cdd:PRK10772  84 VERIATEKLQMQHVDPSQENIVVQK 108
 
Name Accession Description Interval E-value
PRK10772 PRK10772
cell division protein FtsL; Provisional
17-121 1.65e-67

cell division protein FtsL; Provisional


Pssm-ID: 182717  Cd Length: 108  Bit Score: 198.42  E-value: 1.65e-67
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446548305  17 GSNERHALPGVIGDDLLRFGKLPLCLFICIILTAVTVVTTAHHTRLLTAQREQLVLERDALDIEWRNLILEENALGDHSR 96
Cdd:PRK10772   4 GSNERHALPGVIGDDLLRNGKLPLCLFIAVIVSAVTVVTTAHHTRLLTAEREQLVLERDALDIEWRNLILEENALGDHSR 83
                         90       100
                 ....*....|....*....|....*
gi 446548305  97 VERIATEKLQMQHVDPSQENIVVQK 121
Cdd:PRK10772  84 VERIATEKLQMQHVDPSQENIVVQK 108
FtsL pfam04999
Cell division protein FtsL; In Escherichia coli, nine gene products are known to be essential ...
24-119 2.32e-43

Cell division protein FtsL; In Escherichia coli, nine gene products are known to be essential for assembly of the division septum. One of these, FtsL, is a bitopic membrane protein whose precise function is not understood. It has been proposed that FtsL interacts with the DivIC protein pfam04977, however this interaction may be indirect.


Pssm-ID: 428249  Cd Length: 97  Bit Score: 137.00  E-value: 2.32e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446548305   24 LPGVIGDDLLRFGKLPLCLFICIILTAVTVVTTAHHTRLLTAQREQLVLERDALDIEWRNLILEENALGDHSRVERIATE 103
Cdd:pfam04999   1 LSRIILKDLLSHGKLSLLLLILILLSAVGVVYITHQTRQLTAELDKLLLERDRLDIEWRNLLLEESTLSAHSRVERIAVE 80
                          90
                  ....*....|....*.
gi 446548305  104 KLQMQHVDPSQENIVV 119
Cdd:pfam04999  81 QLGMKRPDPEQEVVIR 96
FtsL COG3116
Cell division protein FtsL, interacts with FtsB and FtsQ [Cell cycle control, cell division, ...
32-118 3.83e-34

Cell division protein FtsL, interacts with FtsB and FtsQ [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442350  Cd Length: 88  Bit Score: 113.37  E-value: 3.83e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446548305  32 LLRFGKLPLCLFICIILTAVTVVTTAHHTRLLTAQREQLVLERDALDIEWRNLILEENALGDHSRVERIATEKLQMQHVD 111
Cdd:COG3116    1 MTRAGKLLLLLLLLVLASALAVVYSRHQSRQLFAELERLQAERDQLEVEWGRLQLEQSTLAAHSRIERIAREKLGMRLPT 80

                 ....*..
gi 446548305 112 PSQENIV 118
Cdd:COG3116   81 PAQTVVV 87
ftsL_broad TIGR02209
cell division protein FtsL; This model represents FtsL, both forms similar to that in E. coli ...
35-118 6.76e-28

cell division protein FtsL; This model represents FtsL, both forms similar to that in E. coli and similar to that in B. subtilis. FtsL is one of the later proteins active in cell division septum formation. FtsL is small, low in complexity, and highly divergent. The scope of this model is broader than that of the pfam04999.3 for FtsL, as this one includes FtsL from Bacillus subtilis and related species. [Cellular processes, Cell division]


Pssm-ID: 131264  Cd Length: 85  Bit Score: 97.72  E-value: 6.76e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446548305   35 FGKLPLCLFICIILTAVTVVTTAHHTRLLTAQREQLVLERDALDIEWRNLILEENALGDHSRVERIATEKLQMQHVDPSQ 114
Cdd:TIGR02209   1 EKKLYVLLLLAILVSAISVVSAQHQTRQLNNELQKLQLEIDKLQKEWRDLQLEVAELSRHERIEKIAKKQLGMKLPDANI 80

                  ....
gi 446548305  115 ENIV 118
Cdd:TIGR02209  81 KVVV 84
 
Name Accession Description Interval E-value
PRK10772 PRK10772
cell division protein FtsL; Provisional
17-121 1.65e-67

cell division protein FtsL; Provisional


Pssm-ID: 182717  Cd Length: 108  Bit Score: 198.42  E-value: 1.65e-67
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446548305  17 GSNERHALPGVIGDDLLRFGKLPLCLFICIILTAVTVVTTAHHTRLLTAQREQLVLERDALDIEWRNLILEENALGDHSR 96
Cdd:PRK10772   4 GSNERHALPGVIGDDLLRNGKLPLCLFIAVIVSAVTVVTTAHHTRLLTAEREQLVLERDALDIEWRNLILEENALGDHSR 83
                         90       100
                 ....*....|....*....|....*
gi 446548305  97 VERIATEKLQMQHVDPSQENIVVQK 121
Cdd:PRK10772  84 VERIATEKLQMQHVDPSQENIVVQK 108
FtsL pfam04999
Cell division protein FtsL; In Escherichia coli, nine gene products are known to be essential ...
24-119 2.32e-43

Cell division protein FtsL; In Escherichia coli, nine gene products are known to be essential for assembly of the division septum. One of these, FtsL, is a bitopic membrane protein whose precise function is not understood. It has been proposed that FtsL interacts with the DivIC protein pfam04977, however this interaction may be indirect.


Pssm-ID: 428249  Cd Length: 97  Bit Score: 137.00  E-value: 2.32e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446548305   24 LPGVIGDDLLRFGKLPLCLFICIILTAVTVVTTAHHTRLLTAQREQLVLERDALDIEWRNLILEENALGDHSRVERIATE 103
Cdd:pfam04999   1 LSRIILKDLLSHGKLSLLLLILILLSAVGVVYITHQTRQLTAELDKLLLERDRLDIEWRNLLLEESTLSAHSRVERIAVE 80
                          90
                  ....*....|....*.
gi 446548305  104 KLQMQHVDPSQENIVV 119
Cdd:pfam04999  81 QLGMKRPDPEQEVVIR 96
FtsL COG3116
Cell division protein FtsL, interacts with FtsB and FtsQ [Cell cycle control, cell division, ...
32-118 3.83e-34

Cell division protein FtsL, interacts with FtsB and FtsQ [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442350  Cd Length: 88  Bit Score: 113.37  E-value: 3.83e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446548305  32 LLRFGKLPLCLFICIILTAVTVVTTAHHTRLLTAQREQLVLERDALDIEWRNLILEENALGDHSRVERIATEKLQMQHVD 111
Cdd:COG3116    1 MTRAGKLLLLLLLLVLASALAVVYSRHQSRQLFAELERLQAERDQLEVEWGRLQLEQSTLAAHSRIERIAREKLGMRLPT 80

                 ....*..
gi 446548305 112 PSQENIV 118
Cdd:COG3116   81 PAQTVVV 87
ftsL_broad TIGR02209
cell division protein FtsL; This model represents FtsL, both forms similar to that in E. coli ...
35-118 6.76e-28

cell division protein FtsL; This model represents FtsL, both forms similar to that in E. coli and similar to that in B. subtilis. FtsL is one of the later proteins active in cell division septum formation. FtsL is small, low in complexity, and highly divergent. The scope of this model is broader than that of the pfam04999.3 for FtsL, as this one includes FtsL from Bacillus subtilis and related species. [Cellular processes, Cell division]


Pssm-ID: 131264  Cd Length: 85  Bit Score: 97.72  E-value: 6.76e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446548305   35 FGKLPLCLFICIILTAVTVVTTAHHTRLLTAQREQLVLERDALDIEWRNLILEENALGDHSRVERIATEKLQMQHVDPSQ 114
Cdd:TIGR02209   1 EKKLYVLLLLAILVSAISVVSAQHQTRQLNNELQKLQLEIDKLQKEWRDLQLEVAELSRHERIEKIAKKQLGMKLPDANI 80

                  ....
gi 446548305  115 ENIV 118
Cdd:TIGR02209  81 KVVV 84
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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