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Conserved domains on  [gi|446546132|ref|WP_000623478|]
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MULTISPECIES: CrcB family protein [Staphylococcus]

Protein Classification

fluoride efflux transporter FluC( domain architecture ID 10000802)

fluoride efflux transporter FluC is fluoride-specific ion channel which Important for reducing fluoride concentration in the cell to reduce its toxicity

Gene Ontology:  GO:0022857|GO:0016020|GO:0055085
PubMed:  33492991|25156118
TCDB:  1.A.43

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
CrcB COG0239
Fluoride ion exporter CrcB/FEX, affects chromosome condensation [Cell cycle control, cell ...
 1-117 2.03e-24

Fluoride ion exporter CrcB/FEX, affects chromosome condensation [Cell cycle control, cell division, chromosome partitioning, Inorganic ion transport and metabolism];


:

Pssm-ID: 440009  Cd Length: 125  Bit Score: 89.78  E-value: 2.03e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446546132   1 MISIILVMIGGGFGAITRSAITDYFNHKFTSKLPIATLIVNLVGSFLIGLTIGLSISISWFP----AFFVTGFLGGLTTF 76
Cdd:COG0239    1 MKTLLLVALGGALGALLRYLLSLLLPRLFGSGFPWGTLAVNVLGSFLLGLLLGLLARRGLLSpelrLLLGTGFLGGFTTF 80

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 446546132  77 STLAKELTLMMTPKfNINLFLNYSLLQFIIGFIACYIGYHI 117
Cdd:COG0239   81 STFSLETVRLLERG-RYLLALLYVLLSVVLGLLAAALGLAL 120
 
Name Accession Description Interval E-value
CrcB COG0239
Fluoride ion exporter CrcB/FEX, affects chromosome condensation [Cell cycle control, cell ...
 1-117 2.03e-24

Fluoride ion exporter CrcB/FEX, affects chromosome condensation [Cell cycle control, cell division, chromosome partitioning, Inorganic ion transport and metabolism];


Pssm-ID: 440009  Cd Length: 125  Bit Score: 89.78  E-value: 2.03e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446546132   1 MISIILVMIGGGFGAITRSAITDYFNHKFTSKLPIATLIVNLVGSFLIGLTIGLSISISWFP----AFFVTGFLGGLTTF 76
Cdd:COG0239    1 MKTLLLVALGGALGALLRYLLSLLLPRLFGSGFPWGTLAVNVLGSFLLGLLLGLLARRGLLSpelrLLLGTGFLGGFTTF 80

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 446546132  77 STLAKELTLMMTPKfNINLFLNYSLLQFIIGFIACYIGYHI 117
Cdd:COG0239   81 STFSLETVRLLERG-RYLLALLYVLLSVVLGLLAAALGLAL 120
CRCB pfam02537
CrcB-like protein, Camphor Resistance (CrcB); CRCB is a family of bacterial integral membrane ...
 6-113 1.17e-17

CrcB-like protein, Camphor Resistance (CrcB); CRCB is a family of bacterial integral membrane proteins with four TMs.. Over expression in E. coli also leads to camphor resistance.


Pssm-ID: 460582  Cd Length: 109  Bit Score: 72.12  E-value: 1.17e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446546132    6 LVMIGGGFGAITRSAITdYFNHKFTSKLPIATLIVNLVGSFLIGLTIGLSISISWFPA---FFVTGFLGGLTTFSTLAKE 82
Cdd:pfam02537   1 LVALGGALGALLRYLLS-LLNPRLAGGFPLGTLAVNVLGSFLLGLLAGLLLERGHSPElrlLLGTGFCGGLTTFSTFSLE 79

                          90       100       110
                  ....*....|....*....|....*....|.
gi 446546132   83 LTLMMTPKfNINLFLNYSLLQFIIGFIACYI 113
Cdd:pfam02537  80 TLTLLRAG-QYLLALLYVLLSVVLGLAAVVL 109
PRK14205 PRK14205
fluoride efflux transporter CrcB;
1-114 6.58e-15

fluoride efflux transporter CrcB;


Pssm-ID: 172693  Cd Length: 118  Bit Score: 65.21  E-value: 6.58e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446546132   1 MISIILVMIGGGFGAITRSAITDYFNHKFTSKLPIATLIVNLVGSFLIGLTIGLSISISWfPAFFVTGFLGGLTTFSTLA 80
Cdd:PRK14205   1 MIEALLVATGGFFGAITRFAISNWFKKRNKTSFPIATFLINITGAFLLGYIIGNGVTTGW-QLLLGTGFMGAFTTFSTFK 79

                         90       100       110
                 ....*....|....*....|....*....|....
gi 446546132  81 KELTLMMTPKfNINLFLNYSLLQFIIGFIACYIG 114
Cdd:PRK14205  80 LESVQLLNRK-NFSTFLLYLSATYIVGILFAFLG 112
crcB TIGR00494
protein CrcB; The role of this protein is uncharacterized, but phenotypes associated with ...
 5-117 1.06e-06

protein CrcB; The role of this protein is uncharacterized, but phenotypes associated with overproduction include resistance to camphor, suppression of a mukB chromosomal partition mutant, and chromosome condensation, together suggesting a function related to chromosome folding. [Unknown function, General]


Pssm-ID: 129585  Cd Length: 117  Bit Score: 43.91  E-value: 1.06e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446546132    5 ILVMIGGGFGAITRSAITDYFNHK-FTSKLPIATLIVNLVGSFLIGLTIGLSISISWFPA---FFVTGFLGGLTTFSTLA 80
Cdd:TIGR00494   1 LAIFLGGGPGALLRYLLGIFISAGlFGNSLPLGTLTVNIIGCFGIGFVTLFTQPAVISPDlklLIGTGFLGGFTTFSTFS 80

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 446546132   81 KELTLMMTPKFNINLFLnYSLLQFIIGFIACYIGYHI 117
Cdd:TIGR00494  81 LETTSLLQEGQLGEAVL-YILGTLGGGLIGVALGWLL 116
 
Name Accession Description Interval E-value
CrcB COG0239
Fluoride ion exporter CrcB/FEX, affects chromosome condensation [Cell cycle control, cell ...
 1-117 2.03e-24

Fluoride ion exporter CrcB/FEX, affects chromosome condensation [Cell cycle control, cell division, chromosome partitioning, Inorganic ion transport and metabolism];


Pssm-ID: 440009  Cd Length: 125  Bit Score: 89.78  E-value: 2.03e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446546132   1 MISIILVMIGGGFGAITRSAITDYFNHKFTSKLPIATLIVNLVGSFLIGLTIGLSISISWFP----AFFVTGFLGGLTTF 76
Cdd:COG0239    1 MKTLLLVALGGALGALLRYLLSLLLPRLFGSGFPWGTLAVNVLGSFLLGLLLGLLARRGLLSpelrLLLGTGFLGGFTTF 80

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 446546132  77 STLAKELTLMMTPKfNINLFLNYSLLQFIIGFIACYIGYHI 117
Cdd:COG0239   81 STFSLETVRLLERG-RYLLALLYVLLSVVLGLLAAALGLAL 120
CRCB pfam02537
CrcB-like protein, Camphor Resistance (CrcB); CRCB is a family of bacterial integral membrane ...
 6-113 1.17e-17

CrcB-like protein, Camphor Resistance (CrcB); CRCB is a family of bacterial integral membrane proteins with four TMs.. Over expression in E. coli also leads to camphor resistance.


Pssm-ID: 460582  Cd Length: 109  Bit Score: 72.12  E-value: 1.17e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446546132    6 LVMIGGGFGAITRSAITdYFNHKFTSKLPIATLIVNLVGSFLIGLTIGLSISISWFPA---FFVTGFLGGLTTFSTLAKE 82
Cdd:pfam02537   1 LVALGGALGALLRYLLS-LLNPRLAGGFPLGTLAVNVLGSFLLGLLAGLLLERGHSPElrlLLGTGFCGGLTTFSTFSLE 79

                          90       100       110
                  ....*....|....*....|....*....|.
gi 446546132   83 LTLMMTPKfNINLFLNYSLLQFIIGFIACYI 113
Cdd:pfam02537  80 TLTLLRAG-QYLLALLYVLLSVVLGLAAVVL 109
PRK14205 PRK14205
fluoride efflux transporter CrcB;
1-114 6.58e-15

fluoride efflux transporter CrcB;


Pssm-ID: 172693  Cd Length: 118  Bit Score: 65.21  E-value: 6.58e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446546132   1 MISIILVMIGGGFGAITRSAITDYFNHKFTSKLPIATLIVNLVGSFLIGLTIGLSISISWfPAFFVTGFLGGLTTFSTLA 80
Cdd:PRK14205   1 MIEALLVATGGFFGAITRFAISNWFKKRNKTSFPIATFLINITGAFLLGYIIGNGVTTGW-QLLLGTGFMGAFTTFSTFK 79

                         90       100       110
                 ....*....|....*....|....*....|....
gi 446546132  81 KELTLMMTPKfNINLFLNYSLLQFIIGFIACYIG 114
Cdd:PRK14205  80 LESVQLLNRK-NFSTFLLYLSATYIVGILFAFLG 112
PRK14220 PRK14220
fluoride efflux transporter CrcB;
2-117 1.49e-12

fluoride efflux transporter CrcB;


Pssm-ID: 237641  Cd Length: 120  Bit Score: 59.40  E-value: 1.49e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446546132   2 ISIILVMIGGGFGAITRSAITDYFNHKFT--SKLPIATLIVNLVGSFLIGLTIGLSISISWFpAFFVTGFLGGLTTFSTL 79
Cdd:PRK14220   1 MTILLAGFGASIGAMLRYAITNYGKKHWEqfSNLPTPTLLINLTGAFILGLIFGRKFNPFIY-ALLGTGVLGGYTTFSTL 79

                         90       100       110
                 ....*....|....*....|....*....|....*...
gi 446546132  80 AKELTLMMTPKfNINLFLNYSLLQFIIGFIACYIGYHI 117
Cdd:PRK14220  80 NTELVSLYKSK-NYRVLKLYALLSYLGGLILVFCGYYL 116
PRK14216 PRK14216
fluoride efflux transporter CrcB;
7-114 4.19e-12

fluoride efflux transporter CrcB;


Pssm-ID: 184572  Cd Length: 132  Bit Score: 58.31  E-value: 4.19e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446546132   7 VMIGGGFGAITRSAITDYFNHKfTSKLPIATLIVNLVGSFLIGLTIG-----LSISiSWFPAFFVTGFLGGLTTFSTLAK 81
Cdd:PRK14216  12 VFAGGALGTLARAALSELAAPD-PARWPWPTFTVNVVGAFLLGYFTTrllerLPLS-SYRRPLLGTGLCGGLTTFSTMQV 89

                         90       100       110
                 ....*....|....*....|....*....|...
gi 446546132  82 ElTLMMTPKFNINLFLNYSLLQFIIGFIACYIG 114
Cdd:PRK14216  90 E-TIRMIEHGHWGLAAGYTAASIAAGLLAVHLA 121
PRK14196 PRK14196
fluoride efflux transporter CrcB;
1-82 2.33e-11

fluoride efflux transporter CrcB;


Pssm-ID: 184564  Cd Length: 127  Bit Score: 56.38  E-value: 2.33e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446546132   1 MISIILVMIGGGFGAITRSAITDYFNHKFTSkLPIATLIVNLVGSFLIGLTIGL-----SISISWfPAFFVTGFLGGLTT 75
Cdd:PRK14196   2 LQSLLAVFIGAGLGALLRWLLGLRLNPLFPA-LPLGTLAANLIGGYIIGVAVAWfarmpGLDPEW-RLLIITGFCGGLTT 79


                 ....*..
gi 446546132  76 FSTLAKE 82
Cdd:PRK14196  80 FSTFSAE 86
PRK14195 PRK14195
fluoride efflux transporter CrcB;
1-117 2.92e-11

fluoride efflux transporter CrcB;


Pssm-ID: 184563  Cd Length: 125  Bit Score: 56.20  E-value: 2.92e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446546132   1 MISIILVMIGGGFGAITRSAITDYFNHKFTSKLPIATLIVNLVGSFLIGLTIGLsISISWFPA-----FFVTGFLGGLTT 75
Cdd:PRK14195   1 MINILLVAAGGALGSVARYLVGVGALRLMGPAFPWGTLAVNVTGSFLIGVLAGL-LAHRWNASqewrlFLIVGVLGGFTT 79

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|..
gi 446546132  76 FSTLAKElTLMMTPKFNINLFLNYSLLQFIIGFIACYIGYHI 117
Cdd:PRK14195  80 FSAFSLD-AALLIERGAYGAAAAYIAASVVLSVAALFAGLAI 120
PRK14212 PRK14212
fluoride efflux transporter CrcB;
1-82 6.18e-11

fluoride efflux transporter CrcB;


Pssm-ID: 184569  Cd Length: 128  Bit Score: 55.20  E-value: 6.18e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446546132   1 MISIILVMIGGGFGAITRSAITDYFNHKFTSKLPIATLIVNLVGSFLIGLTIGLSISISWFPA----FFVTGFLGGLTTF 76
Cdd:PRK14212   1 MGEILLLAAGGALGAVSRYGLNNLTVKLLGDSFPYGTLIVNCLGCFVLGFLMQWGFSSDSHNThlklMLTAGFLGAFTTF 80


                 ....*.
gi 446546132  77 STLAKE 82
Cdd:PRK14212  81 STFSYE 86
PRK14211 PRK14211
fluoride efflux transporter CrcB;
2-117 1.52e-10

fluoride efflux transporter CrcB;


Pssm-ID: 172699  Cd Length: 114  Bit Score: 54.17  E-value: 1.52e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446546132   2 ISIILVMIGGGFGAITRSAITDYFNHkfTSKLPIATLIVNLVGSFLIGLTIGLSISISWFpAFFVTGFLGGLTTFSTLAK 81
Cdd:PRK14211   1 MTVLLVALGGALGATTRYLTGRYVDS--YRSFPVATFLVNVAGCLILGLLSGASLSTQTF-ALLGTGFCGGLTTYSTFAV 77

                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 446546132  82 ELTLMMTPKFNInLFLNYSLLQFIIGFIACYIGYHI 117
Cdd:PRK14211  78 ESVGLLRIRQAL-LSVVYIVASVAAGLAAAWLGFRL 112
PRK14214 PRK14214
fluoride efflux transporter CrcB;
1-114 1.88e-10

fluoride efflux transporter CrcB;


Pssm-ID: 184571  Cd Length: 118  Bit Score: 53.72  E-value: 1.88e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446546132   1 MISIILVMIGGGFGAITRSAITDYFNHKFTSKLPIATLIVNLVGSFLIGLTIGLSISISWfPAFFVTGFLGGLTTFSTLA 80
Cdd:PRK14214   2 LVNFLLVGFGAALGAMLRYGISVLVKSKWKTNFPYATFFINITGSFLLGFLVSSALGPVW-QLFLGTGFMGGYTTFSTFK 80

                         90       100       110
                 ....*....|....*....|....*....|....
gi 446546132  81 KElTLMMTPKFNINLFLNYSLLQFIIGFIACYIG 114
Cdd:PRK14214  81 VE-SMELKWKTNYRVLFSYLGCTYVFGLIAAFLG 113
PRK14197 PRK14197
fluoride efflux transporter CrcB;
1-106 4.45e-09

fluoride efflux transporter CrcB;


Pssm-ID: 172685  Cd Length: 124  Bit Score: 50.52  E-value: 4.45e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446546132   1 MISIILVMIGGGFGAITRSAITDYFNHKFTSKLPIATLIVNLVGSFLIGLTIGLSISISWFP---AFFVTGFLGGLTTFS 77
Cdd:PRK14197   1 MNNVLFVALGGSIGAVLRYLISIFMIQVFGSSFPFGTLLVNVLGSFLMGVIYALGQMSHVSPelkALIGVGLLGALTTFS 80

                         90       100       110
                 ....*....|....*....|....*....|...
gi 446546132  78 TLAKELTLMMTP----KFNINLFLNYSLLQFII 106
Cdd:PRK14197  81 TFSNETLLLMQEgawlKAALNVVLNLSLCLFMV 113
PRK14229 PRK14229
fluoride efflux transporter CrcB;
4-117 7.82e-09

fluoride efflux transporter CrcB;


Pssm-ID: 172717  Cd Length: 108  Bit Score: 49.45  E-value: 7.82e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446546132   4 IILVMIGGGFGAITRSAITDYFNHkftSKLPIATLIVNLVGSFLIGLTIGlSISISWFPAFFVTGFLGGLTTFSTLAKEL 83
Cdd:PRK14229   2 IVYLAIACGLGALVRYFFSRYNQA---SKLPLGTLIANLLGCFLIGVFYN-HVESKEVYAILATGFCGGLTTFSTLNDEL 77

                         90       100       110
                 ....*....|....*....|....*....|....
gi 446546132  84 TLMMTPKfniNLFLNYSLLQFIIGFIACYIGYHI 117
Cdd:PRK14229  78 QRLLSDK---KVFYSYLTLTYIGGLVAIFLGILL 108
PRK14208 PRK14208
fluoride efflux transporter CrcB;
1-82 8.16e-09

fluoride efflux transporter CrcB;


Pssm-ID: 172696  Cd Length: 126  Bit Score: 49.96  E-value: 8.16e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446546132   1 MISIILVMIGGGFGAITRSAITDYFNHKFTSKLPIATLIVNLVGSFLIGLTIGLSISISWFPA----FFVTGFLGGLTTF 76
Cdd:PRK14208   1 MARLLLVCLGGALGSGARYLTSAWALRAFGPDFPRGTLLVNVSGSFLLAGIMTASLQSEAVPPdlrlFLAAGVMGGFTTY 80


                 ....*.
gi 446546132  77 STLAKE 82
Cdd:PRK14208  81 SSFNYE 86
PRK14201 PRK14201
fluoride efflux transporter CrcB;
7-114 8.22e-09

fluoride efflux transporter CrcB;


Pssm-ID: 184566  Cd Length: 121  Bit Score: 49.70  E-value: 8.22e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446546132   7 VMIGGGFGAITRSAITdYFNHKFTskLPIATLIVNLVGSFLIGLTIGLSISI----SWFPAFFVTGFLGGLTTFSTLAKE 82
Cdd:PRK14201   6 IFIGGALGALLRYLLS-FLNTDGG--FPIGTLIANLTGAFLMGLLTALTIAFfsnhPTLKKAITTGFLGALTTFSTFQFE 82

                         90       100       110
                 ....*....|....*....|....*....|..
gi 446546132  83 LtLMMTPKFNINLFLNYSLLQFIIGFIACYIG 114
Cdd:PRK14201  83 L-IHMFDHQQFITLLLYAVTSYIFGILLCYVG 113
PRK14202 PRK14202
fluoride efflux transporter CrcB;
1-78 2.71e-08

fluoride efflux transporter CrcB;


Pssm-ID: 172690  Cd Length: 128  Bit Score: 48.56  E-value: 2.71e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446546132   1 MISIILVMIGGGFGAITRSAITDYFNhKFTSKLPIATLIVNLVGSFLIGLTIGLSISISWFPA----FFVTGFLGGLTTF 76
Cdd:PRK14202   5 FSAVLLVGAGGFLGSVARYLVALALS-FIGTGFPFATFTVNLLGSFLIGFISELALSTTLVSPearlLLVTGFCGGFTTF 83


                 ..
gi 446546132  77 ST 78
Cdd:PRK14202  84 SS 85
PRK14223 PRK14223
fluoride efflux transporter CrcB;
1-98 3.13e-08

fluoride efflux transporter CrcB;


Pssm-ID: 184576  Cd Length: 122  Bit Score: 48.14  E-value: 3.13e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446546132   1 MISIILVMIGGGFGAITRSAITDYFNHKFTskLPIATLIVNLVGSFLIGLTIGLSISISWFPA---FFVTGFLGGLTTFS 77
Cdd:PRK14223   1 MRELLLIGIGGFFGAILRYLISGIIPVKFG--IPTGTLIVNLIGSFILGFLLYSSLFGSISPEyrlFIITGFCGALTTFS 78

                         90       100
                 ....*....|....*....|.
gi 446546132  78 TLAKELTLMMTPKFNINLFLN 98
Cdd:PRK14223  79 TFSYETFSLLEEGLYIKALLN 99
PRK14199 PRK14199
fluoride efflux transporter CrcB;
1-115 5.48e-08

fluoride efflux transporter CrcB;


Pssm-ID: 172687  Cd Length: 128  Bit Score: 47.46  E-value: 5.48e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446546132   1 MISIILVMIGGGFGAITRSAITDYFNHKFTSKLPIATLIVNLVGSFLIGLTIGLSISISWFPA----FFVTGFLGGLTTF 76
Cdd:PRK14199   4 LILAIIVGLGGFIGASLRYLISIFAAKMFNGNFPYGTLIVNIVGALLIGFIMEFSMDTALISSnmklFLTTGIMGGLTTF 83

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*
gi 446546132  77 STLAKELTLMMTPK------FNINLFLNYSLLQFIIGFIACYIGY 115
Cdd:PRK14199  84 STFSYETINLITNGnillgiENIILNLGLSLLGVVIGQKLARILF 128
PRK14228 PRK14228
fluoride efflux transporter CrcB;
7-78 7.85e-08

fluoride efflux transporter CrcB;


Pssm-ID: 237643  Cd Length: 122  Bit Score: 47.05  E-value: 7.85e-08
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446546132   7 VMIGGGFGAITRSAITDYFNHKFTSKLPIATLIVNLVGSFLIGLTIGLSISISwfPAFFV-TGFLGGLTTFST 78
Cdd:PRK14228  10 VMLIGGIGSVLRFLVDRTVARRLARTFPYGTLAVNVSGAALLGFLAGLALPKD--AALLAgTAFVGAYTTFST 80
PRK14207 PRK14207
fluoride efflux transporter CrcB;
4-82 9.87e-08

fluoride efflux transporter CrcB;


Pssm-ID: 172695  Cd Length: 123  Bit Score: 46.66  E-value: 9.87e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446546132   4 IILVMIGGGFGAITRSAITDYFnhKFTSKLPIATLIVNLVGSFLIG-----LTIGLSISISWfPAFFVTGFLGGLTTFST 78
Cdd:PRK14207   6 ALAVAIGGGLGALARYYISGLL--PVYKDFPVGTLLVNSIASFILGylyglLFWGFDVSPEW-RAFLGTGFCGGLSTFST 82


                 ....
gi 446546132  79 LAKE 82
Cdd:PRK14207  83 FSYE 86
PRK14232 PRK14232
fluoride efflux transporter CrcB;
5-117 1.13e-07

fluoride efflux transporter CrcB;


Pssm-ID: 237644  Cd Length: 120  Bit Score: 46.70  E-value: 1.13e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446546132   5 ILVMIGGGFGAITRSAITDYFNHKFTSKLPIATLIVNLVGSFLIGLTIGLSISISwFPAFFVTGFLGGLTTFSTLAKELT 84
Cdd:PRK14232   4 VFVGIGGAFGSLARYQLGKVISKKSKSTFPVGTFIINITGAILLGIVSSSNISKN-MYLLLGDGFLGAYTTFSTFMYEGF 82

                         90       100       110
                 ....*....|....*....|....*....|...
gi 446546132  85 LMMTPKFNINLFLnYSLLQFIIGFIACYIGYHI 117
Cdd:PRK14232  83 NLFQEKEKLNAFI-YILGSLIIGIIGYILGFWI 114
PRK14200 PRK14200
fluoride efflux transporter CrcB;
7-117 1.47e-07

fluoride efflux transporter CrcB;


Pssm-ID: 237638  Cd Length: 127  Bit Score: 46.33  E-value: 1.47e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446546132   7 VMIGGGFGAITRSAITDYFNHKFTSKLPIATLIVNLVGSFLIGLTI-----GLSISISWFPAFFVtGFLGGLTTFSTLAK 81
Cdd:PRK14200  10 IALGGAFGACSRYLVSELCVVLLGRGFPYGTLTVNVVGSFIMGLLIaafenELLATEPWRQIIGL-GFLGALTTFSTFSM 88

                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 446546132  82 ELTLMMTPKFNINLFLNYsLLQFIIGFIACYIGYHI 117
Cdd:PRK14200  89 DNVLLMQQGAFFKMGLNV-LLNVVLSISAAWIGFQL 123
PRK14227 PRK14227
fluoride efflux transporter CrcB;
1-82 5.81e-07

fluoride efflux transporter CrcB;


Pssm-ID: 172715  Cd Length: 124  Bit Score: 44.83  E-value: 5.81e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446546132   1 MISIILVMIGGGFGAITRSAITDYFNHKFTSKLPIATLIVNLVGSFLIGLTIGLSIS-ISWFPA---FFVTGFLGGLTTF 76
Cdd:PRK14227   1 MMKYIVVAIGGSIGAILRYFTGVYSAKNLGLDFPYGTLIVNSVGSFILSFFMILFLEkLSLDPLwrlFVAVGFCGSFTTF 80


                 ....*.
gi 446546132  77 STLAKE 82
Cdd:PRK14227  81 SSFTYE 86
PRK14222 PRK14222
fluoride efflux transporter CrcB;
1-82 5.95e-07

fluoride efflux transporter CrcB;


Pssm-ID: 172710  Cd Length: 124  Bit Score: 44.70  E-value: 5.95e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446546132   1 MISIILVMIGGGFGAITRSAITDYFNHKFTSKLPIATLIVNLVGSFLIGLTIGLSISISWFPAFF----VTGFLGGLTTF 76
Cdd:PRK14222   1 METLVYIALFGALGCLARYYLSGWVYALFGRAFPYGTLAVNVIGAFLIGLIMEFSLRSTLIPPTLriglTIGFLGGLTTF 80


                 ....*.
gi 446546132  77 STLAKE 82
Cdd:PRK14222  81 STFSYE 86
PRK14215 PRK14215
fluoride efflux transporter CrcB;
1-114 8.40e-07

fluoride efflux transporter CrcB;


Pssm-ID: 172703  Cd Length: 126  Bit Score: 44.43  E-value: 8.40e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446546132   1 MISIILVMIGGGFGAITRSAITDYFNHKFTSKLPIATLIVNLVGSFLIGLTIGLSISISWFPA----FFVTGFLGGLTTF 76
Cdd:PRK14215   1 MNNILAIAVGAAIGANLRYGIGLWAAQRWGTSWPYGTFIINLLGCLLIGLLLTLATTRLTLSEparlMLVTGLLGGFTTF 80

                         90       100       110
                 ....*....|....*....|....*....|....*...
gi 446546132  77 STLAKElTLMMTPKFNINLFLNYSLLQFIIGFIACYIG 114
Cdd:PRK14215  81 STFGYE-SYSLLSSGNWLAAGGYVVGSVGGGLIAVIIG 117
PRK14234 PRK14234
fluoride efflux transporter CrcB;
1-114 9.05e-07

fluoride efflux transporter CrcB;


Pssm-ID: 172722  Cd Length: 124  Bit Score: 44.38  E-value: 9.05e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446546132   1 MISIIL-VMIGGGFGAITRSAITDYFNHKFTSKLPIATLIVNLVGSFLIGLTIGLSISISWFP----AFFVTGFLGGLTT 75
Cdd:PRK14234   1 MIRLILaVSAGGIAGTLLRFATGNWVSANWPRHFYAATLAVNIVGCLLIGLLYGLFLLRPEVPielrAGLIVGFLGGLTT 80

                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 446546132  76 FSTLAKElTLMMTPKFNINLFLNYSLLQFIIGFIACYIG 114
Cdd:PRK14234  81 FSSFSLD-TLRLLESGQVPLALGYAGISVFGGLLATWAG 118
crcB TIGR00494
protein CrcB; The role of this protein is uncharacterized, but phenotypes associated with ...
 5-117 1.06e-06

protein CrcB; The role of this protein is uncharacterized, but phenotypes associated with overproduction include resistance to camphor, suppression of a mukB chromosomal partition mutant, and chromosome condensation, together suggesting a function related to chromosome folding. [Unknown function, General]


Pssm-ID: 129585  Cd Length: 117  Bit Score: 43.91  E-value: 1.06e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446546132    5 ILVMIGGGFGAITRSAITDYFNHK-FTSKLPIATLIVNLVGSFLIGLTIGLSISISWFPA---FFVTGFLGGLTTFSTLA 80
Cdd:TIGR00494   1 LAIFLGGGPGALLRYLLGIFISAGlFGNSLPLGTLTVNIIGCFGIGFVTLFTQPAVISPDlklLIGTGFLGGFTTFSTFS 80

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 446546132   81 KELTLMMTPKFNINLFLnYSLLQFIIGFIACYIGYHI 117
Cdd:TIGR00494  81 LETTSLLQEGQLGEAVL-YILGTLGGGLIGVALGWLL 116
PRK14209 PRK14209
fluoride efflux transporter CrcB;
3-80 1.06e-06

fluoride efflux transporter CrcB;


Pssm-ID: 237640  Cd Length: 124  Bit Score: 44.16  E-value: 1.06e-06
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446546132   3 SIILVMIGGGFGAITRSAITDYFNHKFTSKLPIATLIVNLVGSFLIG-LTIGLSISISWFPAFFVTGFLGGLTTFSTLA 80
Cdd:PRK14209   4 SLLQVALGGALGASARYLTNVGSMRLFGPAFPVGTMIVNVVGSFLMGvLVVVLAHKGNRYAPFLMTGMLGGFTTFSAFS 82
PRK14218 PRK14218
fluoride efflux transporter CrcB;
3-82 1.07e-06

fluoride efflux transporter CrcB;


Pssm-ID: 184573  Cd Length: 133  Bit Score: 44.49  E-value: 1.07e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446546132   3 SIILVMIGGGFGAITRSAITDYFNHKFTSKLPIATLIVNLVGSFLIGLT---IGLSISISW-FPAFFVTGFLGGLTTFST 78
Cdd:PRK14218   9 SLLLVMLGGAFGSGLRFVIGSCLLQRFGAGFPWGTLAVNLIGSFVAGFLliwLDKRGSAGWpWRMLLIVGLIGGLTTFSS 88


                 ....
gi 446546132  79 LAKE 82
Cdd:PRK14218  89 LMME 92
PRK14233 PRK14233
fluoride efflux transporter CrcB;
5-80 1.35e-06

fluoride efflux transporter CrcB;


Pssm-ID: 172721  Cd Length: 133  Bit Score: 44.10  E-value: 1.35e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446546132   5 ILVMIGGGFGAITRSAITDYFNHKFTSKLPIATLIVNLVGSFLIGLTIGLS------ISISWFPAFFVTGFLGGLTTFST 78
Cdd:PRK14233   7 ILVLVGGFIGGVMRFFLSGYVGRRIGETFPWGTFVVNVSGAFVIGTAAGLGarlggiFSTTIFHEFIMVGLLGGYTTVSS 86


                 ..
gi 446546132  79 LA 80
Cdd:PRK14233  87 FC 88
PRK14206 PRK14206
fluoride efflux transporter CrcB;
5-86 1.63e-06

fluoride efflux transporter CrcB;


Pssm-ID: 172694  Cd Length: 127  Bit Score: 43.64  E-value: 1.63e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446546132   5 ILVMIGGGFGAITRSAITDYFNHKFTSKLPIATLIVNLVGSFLIGLTIGLS-------ISISWfPAFFVTGFLGGLTTFS 77
Cdd:PRK14206   4 LWIALGSALGGTLRFWLSGLVAEATGGTFPWGTLVINVSGSFLIGFFATLTgpegrvfVGESW-RLFVMVGVCGGFTTFS 82

                         90
                 ....*....|
gi 446546132  78 TLA-KELTLM 86
Cdd:PRK14206  83 SFSlQTLNLA 92
ccrB PRK00134
fluoride efflux transporter family protein;
1-80 2.01e-06

fluoride efflux transporter family protein;


Pssm-ID: 234656  Cd Length: 104  Bit Score: 42.86  E-value: 2.01e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446546132   1 MISIILVMIGGGFGAITRSAITDYFnhkftSKLPIATLIVNLVGSFLIGltiglsisisWF--PAFFVTGFLGGLTTFST 78
Cdd:PRK00134   4 LPQGLLVGAGAALGACVRLALTSQL-----GDAPWPILLINVLGAFLMG----------WLrpNAFWGTGFLGGFTSFSA 68


                 ..
gi 446546132  79 LA 80
Cdd:PRK00134  69 FA 70
PRK14198 PRK14198
fluoride efflux transporter CrcB;
5-87 2.83e-06

fluoride efflux transporter CrcB;


Pssm-ID: 172686  Cd Length: 124  Bit Score: 42.81  E-value: 2.83e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446546132   5 ILVMIGGGFGAITRSAITDYFNHKFTSKLPIATLIVNLVGSFLIGLTIGL-----SISISWfPAFFVTGFLGGLTTFSTL 79
Cdd:PRK14198   4 LLVFVGGGLGASLRHAVNMASARLLGTSFPYGTFIINVSGSLVMGLIAGYlafkgGAPQHW-RLFLMTGILGGYTTFSAF 82


                 ....*...
gi 446546132  80 AKELTLMM 87
Cdd:PRK14198  83 SLDAALLY 90
PRK14226 PRK14226
fluoride efflux transporter CrcB;
4-117 3.24e-06

fluoride efflux transporter CrcB;


Pssm-ID: 172714  Cd Length: 130  Bit Score: 42.94  E-value: 3.24e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446546132   4 IILVMIGGGFGAITRSAITDYfNHKFTSKLPIATLIVNLVGSFLIGLTIGLSISISWFP--------AFFVTGFLGGLTT 75
Cdd:PRK14226   5 LLLVGIGGGFGAMARFALTQA-TASISKQIPLGILLCNIIGSLIIGMMAAFLIETKLFNedvstyvrFLLVTGFLGGFTT 83

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|..
gi 446546132  76 FSTLAKELtLMMTPKFNINLFLNYSLLQFIIGFIACYIGYHI 117
Cdd:PRK14226  84 FSSFSLDI-LNLLQRGEIFIAIGYIMVSVLASLIAVILGFYI 124
PRK14217 PRK14217
fluoride efflux transporter CrcB;
5-98 4.17e-06

fluoride efflux transporter CrcB;


Pssm-ID: 172705  Cd Length: 134  Bit Score: 42.68  E-value: 4.17e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446546132   5 ILVMIGGGFGAITRSAITDYFNHKFTSKLPIATLIVNLVGSFLIG----LTIGLSISISWFPAFFVTGFLGGLTTFSTLA 80
Cdd:PRK14217   7 LAVAIGGSLGAMSRYLVTIMAQNAWGIKFPYGTLLVNTLGSFLAGffliVLVGRFSAEESFRLFLFTGFLGAFTTFSSFA 86

                         90
                 ....*....|....*...
gi 446546132  81 KELTLMMTPKFNINLFLN 98
Cdd:PRK14217  87 AESLFMFEQGYWFKLITN 104
PRK14213 PRK14213
camphor resistance protein CrcB; Provisional
 2-90 2.05e-05

camphor resistance protein CrcB; Provisional


Pssm-ID: 184570  Cd Length: 118  Bit Score: 40.57  E-value: 2.05e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446546132   2 ISIILVMIGGGFGAITRSAITDYFNHKFTS-KLPIATLIVNLVGSFLIGLTIGLSISISWFPAFFVTGFLGGLTTFSTLA 80
Cdd:PRK14213   1 MTLAGIFIAGGIGAVLRFWLGNVITAKTKGlSLPIGIMTVNILGSFGLGIFTGLGVDNASVSIIIGTGFFGAFTTFSTFS 80

                         90
                 ....*....|
gi 446546132  81 KELTLMMTPK 90
Cdd:PRK14213  81 VEAVQLLMAK 90
PRK14224 PRK14224
fluoride efflux transporter CrcB;
1-97 1.09e-04

fluoride efflux transporter CrcB;


Pssm-ID: 237642  Cd Length: 126  Bit Score: 38.99  E-value: 1.09e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446546132   1 MISIILVMIGGGFGAITRSAITDyfnhkfTSKLPIATLIVNLVGSFLIGLTIGLSISISWFPA----FFVTGFLGGLTTF 76
Cdd:PRK14224   8 IDKLFLIGAGGFLGAICRFLICE------LIEGQLGTLSVNVLGSFMLGMIMYDTEYIGFIGPkgrlAFGTGFLGAFTTF 81

                         90       100
                 ....*....|....*....|....*
gi 446546132  77 STLA-KELTLMMTPKF---NINLFL 97
Cdd:PRK14224  82 STFAvQSFSMPFVPALgniSANLFL 106
PRK14203 PRK14203
fluoride efflux transporter CrcB;
4-115 2.65e-04

fluoride efflux transporter CrcB;


Pssm-ID: 237639  Cd Length: 132  Bit Score: 37.87  E-value: 2.65e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446546132   4 IILVMIGGGFGAITRSAITDYFNHKFTSKLPIATLIVNLVGSFLIGLTIGLSISI-SWFPA-----FFVTGFLGGLTTFS 77
Cdd:PRK14203   8 LIWVALGSVLGGPARFFLSGLVARRIGETFPWGTLTVNVSGAFAIGIFGALAASGhGLFALpapwlFAVTGFLGCYTTVS 87

                         90       100       110
                 ....*....|....*....|....*....|....*...
gi 446546132  78 TLAKElTLMMTPKFNINLFLNYSLLQFIIGFIACYIGY 115
Cdd:PRK14203  88 SFSLQ-TLTLARDGEFLRALGNVAFSLILCLIAVAIGF 124
PRK14204 PRK14204
fluoride efflux transporter CrcB;
9-117 1.58e-03

fluoride efflux transporter CrcB;


Pssm-ID: 172692  Cd Length: 127  Bit Score: 35.67  E-value: 1.58e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446546132   9 IGGGFGAITRSAITDYFNHKFT--SKLPIATLIVNLVGSFLIGLTIGLSISISW---FPAFFVTGFLGGLTTFSTLAKEl 83
Cdd:PRK14204  10 LGGAIGSSLRYFVGKMMPSKFLmfESFPLGTFSVNIIGCFVIGFMGHLAAKKVFgddFGIFFVTGVLGGFTTFSSYGLD- 88

                         90       100       110
                 ....*....|....*....|....*....|....
gi 446546132  84 TLMMTPKFNINLFLNYSLLQFIIGFIACYIGYHI 117
Cdd:PRK14204  89 TLKLLQKSQYIEAISYVLGTNLLGLIGVAIGWFL 122
ccrB PRK01636
fluoride efflux transporter CrcB;
34-114 2.09e-03

fluoride efflux transporter CrcB;


Pssm-ID: 179312  Cd Length: 118  Bit Score: 35.12  E-value: 2.09e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446546132  34 PIATLIVNLVGSFLIGLTIGL--SISISWFPAFFV-TGFLGGLTTFSTLAKELTLMMTPKFNINLFLNYSLLQFIIGFIA 110
Cdd:PRK01636  18 PLDIFVANVVAAFLLGLTTSLhkRDKISQYVHLMIgTGIMGGLSTFSSFVYGAVEMAKSPGEVLVSICYLVASLIVGYIA 97


                 ....
gi 446546132 111 CYIG 114
Cdd:PRK01636  98 VELG 101
PRK14219 PRK14219
fluoride efflux transporter CrcB;
5-82 5.90e-03

fluoride efflux transporter CrcB;


Pssm-ID: 172707  Cd Length: 132  Bit Score: 34.05  E-value: 5.90e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446546132   5 ILVMIGGGFGAITRSAITDYFNHKFTSKLPIATLIVNLVGSFLIGLTIGLSISISWFPAFFV----TGFLGGLTTFSTLA 80
Cdd:PRK14219   4 IIVGIAGILGALSRYYLGLTIHEFWHHTFPLATLLINLAGCFLLAWLTTYIAKLNILPSDVItgigTGFIGSFTTFSTFS 83


                 ..
gi 446546132  81 KE 82
Cdd:PRK14219  84 VE 85
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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