|
Name |
Accession |
Description |
Interval |
E-value |
| Uup |
COG0488 |
ATPase components of ABC transporters with duplicated ATPase domains [General function ... |
6-534 |
0e+00 |
|
ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];
Pssm-ID: 440254 [Multi-domain] Cd Length: 520 Bit Score: 646.74 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 6 LNHISKSFDGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNVSKIKNLKLGYLTQQMTLNSNATVFE 85
Cdd:COG0488 1 LENLSKSFGGRPLLDDVSLSINPGDRIGLVGRNGAGKSTLLKILAGELEPDSGEVSIPKGLRIGYLPQEPPLDDDLTVLD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 86 EMSKPFEHIKRMESLIKEetdwLSKHANDYDSDtykthMSRYESLSNQFEQLEGYQYESKIKTVLHGLNFSEEDFNKPIN 165
Cdd:COG0488 81 TVLDGDAELRALEAELEE----LEAKLAEPDED-----LERLAELQEEFEALGGWEAEARAEEILSGLGFPEEDLDRPVS 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 166 DFSGGQKTRLSLAQ----------MllnepdllllDEPTNHLDLETTKWLEDYLRYFKGAIVIISHDRYFLDKIVTQIYD 235
Cdd:COG0488 152 ELSGGWRRRVALARallsepdlllL----------DEPTNHLDLESIEWLEEFLKNYPGTVLVVSHDRYFLDRVATRILE 221
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 236 VALGDVKRYVGNYEEFIQQRDLYYQKRMQEYESQQAEIKRLETFVEKNITRASTSGMAKSRRKILEKMERIDKPMLDaKS 315
Cdd:COG0488 222 LDRGKLTLYPGNYSAYLEQRAERLEQEAAAYAKQQKKIAKEEEFIRRFRAKARKAKQAQSRIKALEKLEREEPPRRD-KT 300
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 316 ANIQFGFDRNTGNDVMHVKNLEIGY-QTAITKPISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITFGANLQI 394
Cdd:COG0488 301 VEIRFPPPERLGKKVLELEGLSKSYgDKTLLDDLSLRIDRGDRIGLIGPNGAGKSTLLKLLAGELEPDSGTVKLGETVKI 380
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 395 GYYDQKQAEFKSSKTILDYVWDQYPLMNEKDIRAVLGRFLFVQDDVKKIINDLSGGEKARLQLALLMLQRDNVLILDEPT 474
Cdd:COG0488 381 GYFDQHQEELDPDKTVLDELRDGAPGGTEQEVRGYLGRFLFSGDDAFKPVGVLSGGEKARLALAKLLLSPPNVLLLDEPT 460
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446524717 475 NHLDIDSKEMLEQALQHFEGTILFVSHDRYFINQLANKVFDLTiDGG-KMYLGDYQYYIEK 534
Cdd:COG0488 461 NHLDIETLEALEEALDDFPGTVLLVSHDRYFLDRVATRILEFE-DGGvREYPGGYDDYLEK 520
|
|
| PRK15064 |
PRK15064 |
ABC transporter ATP-binding protein; Provisional |
3-531 |
3.59e-106 |
|
ABC transporter ATP-binding protein; Provisional
Pssm-ID: 237894 [Multi-domain] Cd Length: 530 Bit Score: 331.47 E-value: 3.59e-106
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 3 LLQLNHISKSFDGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNVSKIKNLKLGYLTQqmtlnsNAT 82
Cdd:PRK15064 1 MLSTANITMQFGAKPLFENISVKFGGGNRYGLIGANGCGKSTFMKILGGDLEPSAGNVSLDPNERLGKLRQ------DQF 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 83 VFEEMSKPFEHIKRMESL--IKEETDWLSKHANDYDSDTYKThmsryESLSNQFEQLEGYQYESKIKTVLHGLNFSEEDF 160
Cdd:PRK15064 75 AFEEFTVLDTVIMGHTELweVKQERDRIYALPEMSEEDGMKV-----ADLEVKFAEMDGYTAEARAGELLLGVGIPEEQH 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 161 NKPINDFSGGQKTRLSLAQMLLNEPDLLLLDEPTNHLDLETTKWLEDYLRYFKGAIVIISHDRYFLDKIVTQIYDVALGD 240
Cdd:PRK15064 150 YGLMSEVAPGWKLRVLLAQALFSNPDILLLDEPTNNLDINTIRWLEDVLNERNSTMIIISHDRHFLNSVCTHMADLDYGE 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 241 VKRYVGNYEEFIQQRDLYYQKRMQEYESQQAEIKRLETFVEKNITRASTSGMAKSRRKILEKMErIDkpmlDAKSAN--- 317
Cdd:PRK15064 230 LRVYPGNYDEYMTAATQARERLLADNAKKKAQIAELQSFVSRFSANASKAKQATSRAKQIDKIK-LE----EVKPSSrqn 304
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 318 --IQFGFDRNTGNDVMHVKNLEIGYQTA-ITKPISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITFGANLQI 394
Cdd:PRK15064 305 pfIRFEQDKKLHRNALEVENLTKGFDNGpLFKNLNLLLEAGERLAIIGENGVGKTTLLRTLVGELEPDSGTVKWSENANI 384
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 395 GYYDQKQA-EFKSSKTILDYV--WDQyPLMNEKDIRAVLGRFLFVQDDVKKIINDLSGGEKARLQLALLMLQRDNVLILD 471
Cdd:PRK15064 385 GYYAQDHAyDFENDLTLFDWMsqWRQ-EGDDEQAVRGTLGRLLFSQDDIKKSVKVLSGGEKGRMLFGKLMMQKPNVLVMD 463
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 472 EPTNHLDIDSKEMLEQALQHFEGTILFVSHDRYFINQLANKVFDLTIDGGKMYLGDYQYY 531
Cdd:PRK15064 464 EPTNHMDMESIESLNMALEKYEGTLIFVSHDREFVSSLATRIIEITPDGVVDFSGTYEEY 523
|
|
| PRK11147 |
PRK11147 |
ABC transporter ATPase component; Reviewed |
1-639 |
1.36e-104 |
|
ABC transporter ATPase component; Reviewed
Pssm-ID: 236861 [Multi-domain] Cd Length: 635 Bit Score: 330.37 E-value: 1.36e-104
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 1 MILLQLNHISKSFDGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNVSKIKNLKLGYLTQQMTLNSN 80
Cdd:PRK11147 1 MSLISIHGAWLSFSDAPLLDNAELHIEDNERVCLVGRNGAGKSTLMKILNGEVLLDDGRIIYEQDLIVARLQQDPPRNVE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 81 ATVFEEMSkpfEHIKRMESLIKEETDWLSKHANDYdSDTyktHMSRYESLSNQFEQLEGYQYESKIKTVLHGLNFseeDF 160
Cdd:PRK11147 81 GTVYDFVA---EGIEEQAEYLKRYHDISHLVETDP-SEK---NLNELAKLQEQLDHHNLWQLENRINEVLAQLGL---DP 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 161 NKPINDFSGGQKTRLSLAQMLLNEPDLLLLDEPTNHLDLETTKWLEDYLRYFKGAIVIISHDRYFLDKIVTQIYDVALGD 240
Cdd:PRK11147 151 DAALSSLSGGWLRKAALGRALVSNPDVLLLDEPTNHLDIETIEWLEGFLKTFQGSIIFISHDRSFIRNMATRIVDLDRGK 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 241 VKRYVGNYEEFIQQRdlyyQKRMQEYESQQAEI-KRL---ETFVEKNItrastsgmaKSRR----------KIL--EKME 304
Cdd:PRK11147 231 LVSYPGNYDQYLLEK----EEALRVEELQNAEFdRKLaqeEVWIRQGI---------KARRtrnegrvralKALrrERSE 297
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 305 RIDKPmldaKSANIQFGFDRNTGNDVMHVKNLEigYQTA---ITKPISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKA 381
Cdd:PRK11147 298 RREVM----GTAKMQVEEASRSGKIVFEMENVN--YQIDgkqLVKDFSAQVQRGDKIALIGPNGCGKTTLLKLMLGQLQA 371
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 382 LNGYITFGANLQIGYYDQKQAEFKSSKTILDYVWD--QYPLMNEKDiRAVLG---RFLFVQDDVKKIINDLSGGEKARLQ 456
Cdd:PRK11147 372 DSGRIHCGTKLEVAYFDQHRAELDPEKTVMDNLAEgkQEVMVNGRP-RHVLGylqDFLFHPKRAMTPVKALSGGERNRLL 450
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 457 LALLMLQRDNVLILDEPTNHLDIDSKEMLEQALQHFEGTILFVSHDRYFINQLANKVFDLTIDGG-KMYLGDY------- 528
Cdd:PRK11147 451 LARLFLKPSNLLILDEPTNDLDVETLELLEELLDSYQGTVLLVSHDRQFVDNTVTECWIFEGNGKiGRYVGGYhdarqqq 530
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 529 -QYYIEKVEEAEALKAHQEEQSVNVQAHEKSMeqsSYHNQkeqrREQRKLERQISECENEIETLEttilqidEQLTQPEV 607
Cdd:PRK11147 531 aQYLALKQPAVKKKEEAAAPKAETVKRSSKKL---SYKLQ----RELEQLPQLLEDLEAEIEALQ-------AQVADADF 596
|
650 660 670
....*....|....*....|....*....|...
gi 446524717 608 YNNPQKANELAIQK-QDSEQKLEHAMSKWEELQ 639
Cdd:PRK11147 597 FSQPHEQTQKVLADlADAEQELEVAFERWEELE 629
|
|
| PRK10636 |
PRK10636 |
putative ABC transporter ATP-binding protein; Provisional |
26-642 |
1.11e-99 |
|
putative ABC transporter ATP-binding protein; Provisional
Pssm-ID: 236729 [Multi-domain] Cd Length: 638 Bit Score: 317.88 E-value: 1.11e-99
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 26 VKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNVSKIKNLKLGYLTQQmTLNSNATVFEEMSKPFEHIKRMESLIKEET 105
Cdd:PRK10636 24 INPGQKVGLVGKNGCGKSTLLALLKNEISADGGSYTFPGNWQLAWVNQE-TPALPQPALEYVIDGDREYRQLEAQLHDAN 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 106 DWLSKHAndydsdtykthmsrYESLSNQFEQLEGYQYESKIKTVLHGLNFSEEDFNKPINDFSGGQKTRLSLAQMLLNEP 185
Cdd:PRK10636 103 ERNDGHA--------------IATIHGKLDAIDAWTIRSRAASLLHGLGFSNEQLERPVSDFSGGWRMRLNLAQALICRS 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 186 DLLLLDEPTNHLDLETTKWLEDYLRYFKGAIVIISHDRYFLDKIVTQIYDVALGDVKRYVGNYEEFIQQRDLYYQKRMQE 265
Cdd:PRK10636 169 DLLLLDEPTNHLDLDAVIWLEKWLKSYQGTLILISHDRDFLDPIVDKIIHIEQQSLFEYTGNYSSFEVQRATRLAQQQAM 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 266 YESQQAEIKRLETFVEKNITRASTSGMAKSRRKILEKMERIDKPMLDAKsanIQFGFDR--NTGNDVMHVKNLEIGY-QT 342
Cdd:PRK10636 249 YESQQERVAHLQSYIDRFRAKATKAKQAQSRIKMLERMELIAPAHVDNP---FHFSFRApeSLPNPLLKMEKVSAGYgDR 325
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 343 AITKPISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITFGANLQIGYYDQKQAEF-KSSKTILDYVWDQYPLM 421
Cdd:PRK10636 326 IILDSIKLNLVPGSRIGLLGRNGAGKSTLIKLLAGELAPVSGEIGLAKGIKLGYFAQHQLEFlRADESPLQHLARLAPQE 405
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 422 NEKDIRAVLGRFLFVQDDVKKIINDLSGGEKARLQLALLMLQRDNVLILDEPTNHLDIDSKEMLEQALQHFEGTILFVSH 501
Cdd:PRK10636 406 LEQKLRDYLGGFGFQGDKVTEETRRFSGGEKARLVLALIVWQRPNLLLLDEPTNHLDLDMRQALTEALIDFEGALVVVSH 485
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 502 DRYFINQLANK---VFDLTIDGGKMYLGDYQYYIEKVEEAEALKAHQEEQSVNVQAHEKSMEQssyHNQKEQRREQRKLE 578
Cdd:PRK10636 486 DRHLLRSTTDDlylVHDGKVEPFDGDLEDYQQWLSDVQKQENQTDEAPKENNANSAQARKDQK---RREAELRTQTQPLR 562
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446524717 579 RQISECENEIETLETTILQIDEQLTQPEVYNNPQKAnEL--AIQKQDS-EQKLEHAMSKWEELQQKL 642
Cdd:PRK10636 563 KEIARLEKEMEKLNAQLAQAEEKLGDSELYDQSRKA-ELtaCLQQQASaKSGLEECEMAWLEAQEQL 628
|
|
| ABC_ABC_ChvD |
TIGR03719 |
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ... |
2-533 |
5.38e-91 |
|
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.
Pssm-ID: 274744 [Multi-domain] Cd Length: 552 Bit Score: 292.61 E-value: 5.38e-91
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 2 ILLQLNHISKSFD-GEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNVSKIKNLKLGYLTQQMTLNSN 80
Cdd:TIGR03719 3 YIYTMNRVSKVVPpKKEILKDISLSFFPGAKIGVLGLNGAGKSTLLRIMAGVDKDFNGEARPQPGIKVGYLPQEPQLDPT 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 81 ATVFEEMSKPFEHIKRMESLIKEETDWLSKHANDYDSdtyktHMSRYESLSNQFEQLEGYQYESKIKTVLHGLNFSEEDf 160
Cdd:TIGR03719 83 KTVRENVEEGVAEIKDALDRFNEISAKYAEPDADFDK-----LAAEQAELQEIIDAADAWDLDSQLEIAMDALRCPPWD- 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 161 nKPINDFSGGQKTRLSLAQMLLNEPDLLLLDEPTNHLDLETTKWLEDYLRYFKGAIVIISHDRYFLDKIVTQIYDVALGD 240
Cdd:TIGR03719 157 -ADVTKLSGGERRRVALCRLLLSKPDMLLLDEPTNHLDAESVAWLERHLQEYPGTVVAVTHDRYFLDNVAGWILELDRGR 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 241 VKRYVGNYEEFIQQRdlyyQKRM-QEYESQQAEIKRLETfvEKNITRASTSG-MAKSRRKI--LEKMERIDKPMlDAKSA 316
Cdd:TIGR03719 236 GIPWEGNYSSWLEQK----QKRLeQEEKEESARQKTLKR--ELEWVRQSPKGrQAKSKARLarYEELLSQEFQK-RNETA 308
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 317 NIQFGFDRNTGNDVMHVKNLEIGY-QTAITKPISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITFGANLQIG 395
Cdd:TIGR03719 309 EIYIPPGPRLGDKVIEAENLTKAFgDKLLIDDLSFKLPPGGIVGVIGPNGAGKSTLFRMITGQEQPDSGTIEIGETVKLA 388
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 396 YYDQKQAEFKSSKTILDYVWDQYPLM--NEKDI--RAVLGRFLFVQDDVKKIINDLSGGEKARLQLALLMLQRDNVLILD 471
Cdd:TIGR03719 389 YVDQSRDALDPNKTVWEEISGGLDIIklGKREIpsRAYVGRFNFKGSDQQKKVGQLSGGERNRVHLAKTLKSGGNVLLLD 468
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446524717 472 EPTNHLDIDSKEMLEQALQHFEGTILFVSHDRYFINQLANKVFDLTIDGGKMYL-GDYQYYIE 533
Cdd:TIGR03719 469 EPTNDLDVETLRALEEALLNFAGCAVVISHDRWFLDRIATHILAFEGDSHVEWFeGNFSEYEE 531
|
|
| PRK11819 |
PRK11819 |
putative ABC transporter ATP-binding protein; Reviewed |
5-510 |
8.16e-80 |
|
putative ABC transporter ATP-binding protein; Reviewed
Pssm-ID: 236992 [Multi-domain] Cd Length: 556 Bit Score: 263.13 E-value: 8.16e-80
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 5 QLNHISKSFDGE-DIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNVSKIKNLKLGYLTQQMTLNSNATV 83
Cdd:PRK11819 8 TMNRVSKVVPPKkQILKDISLSFFPGAKIGVLGLNGAGKSTLLRIMAGVDKEFEGEARPAPGIKVGYLPQEPQLDPEKTV 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 84 FEEMSKPFEHIKRmeslIKEETDWLSKHANDYDSDTYKThMSRYESLSNQFEQLEGYQYESKIKTVLHGLNFSEEDfnKP 163
Cdd:PRK11819 88 RENVEEGVAEVKA----ALDRFNEIYAAYAEPDADFDAL-AAEQGELQEIIDAADAWDLDSQLEIAMDALRCPPWD--AK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 164 INDFSGGQKTRLSLAQMLLNEPDLLLLDEPTNHLDLETTKWLEDYLRYFKGAIVIISHDRYFLDKIVTQIYDVALGDVKR 243
Cdd:PRK11819 161 VTKLSGGERRRVALCRLLLEKPDMLLLDEPTNHLDAESVAWLEQFLHDYPGTVVAVTHDRYFLDNVAGWILELDRGRGIP 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 244 YVGNYEEFIQQRdlyyQKRM-QEYESQQAEIKRLETfvEKNITRASTSG-MAKSRRKI--LEKM------ERIDKpmlda 313
Cdd:PRK11819 241 WEGNYSSWLEQK----AKRLaQEEKQEAARQKALKR--ELEWVRQSPKArQAKSKARLarYEELlseeyqKRNET----- 309
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 314 ksANIQFGFDRNTGNDVMHVKNLEIGY--QTAItKPISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITFGAN 391
Cdd:PRK11819 310 --NEIFIPPGPRLGDKVIEAENLSKSFgdRLLI-DDLSFSLPPGGIVGIIGPNGAGKSTLFKMITGQEQPDSGTIKIGET 386
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 392 LQIGYYDQKQAEFKSSKTildyVWDQ------YPLMNEKDI--RAVLGRFLFVQDDVKKIINDLSGGEKARLQLALLMLQ 463
Cdd:PRK11819 387 VKLAYVDQSRDALDPNKT----VWEEisggldIIKVGNREIpsRAYVGRFNFKGGDQQKKVGVLSGGERNRLHLAKTLKQ 462
|
490 500 510 520
....*....|....*....|....*....|....*....|....*..
gi 446524717 464 RDNVLILDEPTNHLDIDSKEMLEQALQHFEGTILFVSHDRYFINQLA 510
Cdd:PRK11819 463 GGNVLLLDEPTNDLDVETLRALEEALLEFPGCAVVISHDRWFLDRIA 509
|
|
| PLN03073 |
PLN03073 |
ABC transporter F family; Provisional |
4-507 |
7.40e-65 |
|
ABC transporter F family; Provisional
Pssm-ID: 215558 [Multi-domain] Cd Length: 718 Bit Score: 227.05 E-value: 7.40e-65
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 4 LQLNHISKSFDGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIA-----GVEnydsgnvskiKNLKLGYLTQQMTLN 78
Cdd:PLN03073 178 IHMENFSISVGGRDLIVDASVTLAFGRHYGLVGRNGTGKTTFLRYMAmhaidGIP----------KNCQILHVEQEVVGD 247
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 79 SNATVFEEMSKPFEHIKRMESLIK--------EETDWLSKHANDYDSDTYKTHMS-RYESLSNQFEQLEGYQYESKIKTV 149
Cdd:PLN03073 248 DTTALQCVLNTDIERTQLLEEEAQlvaqqrelEFETETGKGKGANKDGVDKDAVSqRLEEIYKRLELIDAYTAEARAASI 327
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 150 LHGLNFSEEDFNKPINDFSGGQKTRLSLAQMLLNEPDLLLLDEPTNHLDLETTKWLEDYLRYFKGAIVIISHDRYFLDKI 229
Cdd:PLN03073 328 LAGLSFTPEMQVKATKTFSGGWRMRIALARALFIEPDLLLLDEPTNHLDLHAVLWLETYLLKWPKTFIVVSHAREFLNTV 407
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 230 VTQIYDVALGDVKRYVGNYEEFIQQRDLYYQKRMQEYESQQAEIKRLETFVEKNITRASTSGMAKSRRKILEKMERIDKP 309
Cdd:PLN03073 408 VTDILHLHGQKLVTYKGDYDTFERTREEQLKNQQKAFESNERSRSHMQAFIDKFRYNAKRASLVQSRIKALDRLGHVDAV 487
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 310 MLDaksANIQFGF---DRNTGNDVMHVKNLEIGYQTA--ITKPISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNG 384
Cdd:PLN03073 488 VND---PDYKFEFptpDDRPGPPIISFSDASFGYPGGplLFKNLNFGIDLDSRIAMVGPNGIGKSTILKLISGELQPSSG 564
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 385 YITFGANLQIGYYDQKQAE-FKSSKTILDYVWDQYPLMNEKDIRAVLGRFLFVQDDVKKIINDLSGGEKARLQLALLMLQ 463
Cdd:PLN03073 565 TVFRSAKVRMAVFSQHHVDgLDLSSNPLLYMMRCFPGVPEQKLRAHLGSFGVTGNLALQPMYTLSGGQKSRVAFAKITFK 644
|
490 500 510 520
....*....|....*....|....*....|....*....|....
gi 446524717 464 RDNVLILDEPTNHLDIDSKEMLEQALQHFEGTILFVSHDRYFIN 507
Cdd:PLN03073 645 KPHILLLDEPSNHLDLDAVEALIQGLVLFQGGVLMVSHDEHLIS 688
|
|
| Uup |
COG0488 |
ATPase components of ABC transporters with duplicated ATPase domains [General function ... |
2-254 |
1.45e-63 |
|
ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];
Pssm-ID: 440254 [Multi-domain] Cd Length: 520 Bit Score: 218.78 E-value: 1.45e-63
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 2 ILLQLNHISKSFDGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNVSKIKNLKLGYLTQ-QMTLNSN 80
Cdd:COG0488 314 KVLELEGLSKSYGDKTLLDDLSLRIDRGDRIGLIGPNGAGKSTLLKLLAGELEPDSGTVKLGETVKIGYFDQhQEELDPD 393
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 81 ATVFEEMSkpfehikrmeslikeetdwlskhanDYDSDTYKTHmsryeslsnqfeqlegyqyeskIKTVLHGLNFSEEDF 160
Cdd:COG0488 394 KTVLDELR-------------------------DGAPGGTEQE----------------------VRGYLGRFLFSGDDA 426
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 161 NKPINDFSGGQKTRLSLAQMLLNEPDLLLLDEPTNHLDLETTKWLEDYLRYFKGAIVIISHDRYFLDKIVTQIYDVALGD 240
Cdd:COG0488 427 FKPVGVLSGGEKARLALAKLLLSPPNVLLLDEPTNHLDIETLEALEEALDDFPGTVLLVSHDRYFLDRVATRILEFEDGG 506
|
250
....*....|....
gi 446524717 241 VKRYVGNYEEFIQQ 254
Cdd:COG0488 507 VREYPGGYDDYLEK 520
|
|
| Uup |
COG0488 |
ATPase components of ABC transporters with duplicated ATPase domains [General function ... |
348-580 |
1.69e-53 |
|
ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];
Pssm-ID: 440254 [Multi-domain] Cd Length: 520 Bit Score: 191.43 E-value: 1.69e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 348 ISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITFGANLQIGYYDQkQAEFKSSKTILDYVWD----QYPLMNE 423
Cdd:COG0488 17 VSLSINPGDRIGLVGRNGAGKSTLLKILAGELEPDSGEVSIPKGLRIGYLPQ-EPPLDDDLTVLDTVLDgdaeLRALEAE 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 424 KD----------------------------------IRAVLGRFLFVQDDVKKIINDLSGGEKARLQLALLMLQRDNVLI 469
Cdd:COG0488 96 LEeleaklaepdedlerlaelqeefealggweaearAEEILSGLGFPEEDLDRPVSELSGGWRRRVALARALLSEPDLLL 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 470 LDEPTNHLDIDSKEMLEQALQHFEGTILFVSHDRYFINQLANKVFDLtiDGGK--MYLGDYQYYIEKVEEAEALKAHQEE 547
Cdd:COG0488 176 LDEPTNHLDLESIEWLEEFLKNYPGTVLVVSHDRYFLDRVATRILEL--DRGKltLYPGNYSAYLEQRAERLEQEAAAYA 253
|
250 260 270
....*....|....*....|....*....|....*....
gi 446524717 548 QSVNVQAHEKS-MEQSSYHNQKE---QRREQR--KLERQ 580
Cdd:COG0488 254 KQQKKIAKEEEfIRRFRAKARKAkqaQSRIKAleKLERE 292
|
|
| ABCF_EF-3 |
cd03221 |
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is ... |
332-517 |
1.17e-52 |
|
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is a cytosolic protein required by fungal ribosomes for in vitro protein synthesis and for in vivo growth. EF-3 stimulates the binding of the EF-1: GTP: aa-tRNA ternary complex to the ribosomal A site by facilitated release of the deacylated tRNA from the E site. The reaction requires ATP hydrolysis. EF-3 contains two ATP nucleotide binding sequence (NBS) motifs. NBSI is sufficient for the intrinsic ATPase activity. NBSII is essential for the ribosome-stimulated functions.
Pssm-ID: 213188 [Multi-domain] Cd Length: 144 Bit Score: 177.64 E-value: 1.17e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 332 HVKNLEIGY-QTAITKPISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITFGANLQIGYYDQkqaefksskti 410
Cdd:cd03221 2 ELENLSKTYgGKLLLKDISLTINPGDRIGLVGRNGAGKSTLLKLIAGELEPDEGIVTWGSTVKIGYFEQ----------- 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 411 ldyvwdqyplmnekdiravlgrflfvqddvkkiindLSGGEKARLQLALLMLQRDNVLILDEPTNHLDIDSKEMLEQALQ 490
Cdd:cd03221 71 ------------------------------------LSGGEKMRLALAKLLLENPNLLLLDEPTNHLDLESIEALEEALK 114
|
170 180
....*....|....*....|....*..
gi 446524717 491 HFEGTILFVSHDRYFINQLANKVFDLT 517
Cdd:cd03221 115 EYPGTVILVSHDRYFLDQVATKIIELE 141
|
|
| ABCF_EF-3 |
cd03221 |
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is ... |
4-236 |
1.18e-44 |
|
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is a cytosolic protein required by fungal ribosomes for in vitro protein synthesis and for in vivo growth. EF-3 stimulates the binding of the EF-1: GTP: aa-tRNA ternary complex to the ribosomal A site by facilitated release of the deacylated tRNA from the E site. The reaction requires ATP hydrolysis. EF-3 contains two ATP nucleotide binding sequence (NBS) motifs. NBSI is sufficient for the intrinsic ATPase activity. NBSII is essential for the ribosome-stimulated functions.
Pssm-ID: 213188 [Multi-domain] Cd Length: 144 Bit Score: 155.68 E-value: 1.18e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 4 LQLNHISKSFDGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNVSKIKNLKLGYLTQqmtlnsnatv 83
Cdd:cd03221 1 IELENLSKTYGGKLLLKDISLTINPGDRIGLVGRNGAGKSTLLKLIAGELEPDEGIVTWGSTVKIGYFEQ---------- 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 84 feemskpfehikrmeslikeetdwlskhandydsdtykthmsryeslsnqfeqlegyqyeskiktvlhglnfseedfnkp 163
Cdd:cd03221 --------------------------------------------------------------------------------
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446524717 164 indFSGGQKTRLSLAQMLLNEPDLLLLDEPTNHLDLETTKWLEDYLRYFKGAIVIISHDRYFLDKIVTQIYDV 236
Cdd:cd03221 71 ---LSGGEKMRLALAKLLLENPNLLLLDEPTNHLDLESIEALEEALKEYPGTVILVSHDRYFLDQVATKIIEL 140
|
|
| FetA |
COG4619 |
ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism]; |
333-523 |
2.14e-32 |
|
ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443661 [Multi-domain] Cd Length: 209 Bit Score: 124.16 E-value: 2.14e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 333 VKNLEIGY-QTAITKPISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITF-GANL----------QIGYYDQK 400
Cdd:COG4619 3 LEGLSFRVgGKPILSPVSLTLEAGECVAITGPSGSGKSTLLRALADLDPPTSGEIYLdGKPLsampppewrrQVAYVPQE 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 401 QAEFKSS-KTILDYVWD-QYPLMNEKDIRAVLGRFLFVQDDVKKIINDLSGGEKARLQLA-LLMLQRDnVLILDEPTNHL 477
Cdd:COG4619 83 PALWGGTvRDNLPFPFQlRERKFDRERALELLERLGLPPDILDKPVERLSGGERQRLALIrALLLQPD-VLLLDEPTSAL 161
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 446524717 478 DIDSKEMLEQALQHF----EGTILFVSHDRYFINQLANKVfdLTIDGGKM 523
Cdd:COG4619 162 DPENTRRVEELLREYlaeeGRAVLWVSHDPEQIERVADRV--LTLEAGRL 209
|
|
| PRK11819 |
PRK11819 |
putative ABC transporter ATP-binding protein; Reviewed |
7-255 |
4.78e-32 |
|
putative ABC transporter ATP-binding protein; Reviewed
Pssm-ID: 236992 [Multi-domain] Cd Length: 556 Bit Score: 131.01 E-value: 4.78e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 7 NHISKSFDGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNVSKIKNLKLGYLTQQM-TLNSNATVFE 85
Cdd:PRK11819 328 ENLSKSFGDRLLIDDLSFSLPPGGIVGIIGPNGAGKSTLFKMITGQEQPDSGTIKIGETVKLAYVDQSRdALDPNKTVWE 407
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 86 EMSKPFEHIKrmesLIKEETDwlskhandydsdtykthmSRyeslsnqfeqlegyQYESKiktvlhgLNFSEEDFNKPIN 165
Cdd:PRK11819 408 EISGGLDIIK----VGNREIP------------------SR--------------AYVGR-------FNFKGGDQQKKVG 444
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 166 DFSGGQKTRLSLAQMLLNEPDLLLLDEPTNHLDLETTKWLEDYLRYFKGAIVIISHDRYFLDKIVTQIYDvALGD--VKR 243
Cdd:PRK11819 445 VLSGGERNRLHLAKTLKQGGNVLLLDEPTNDLDVETLRALEEALLEFPGCAVVISHDRWFLDRIATHILA-FEGDsqVEW 523
|
250
....*....|..
gi 446524717 244 YVGNYEEFIQQR 255
Cdd:PRK11819 524 FEGNFQEYEEDK 535
|
|
| PRK15064 |
PRK15064 |
ABC transporter ATP-binding protein; Provisional |
4-255 |
1.82e-31 |
|
ABC transporter ATP-binding protein; Provisional
Pssm-ID: 237894 [Multi-domain] Cd Length: 530 Bit Score: 128.86 E-value: 1.82e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 4 LQLNHISKSFDGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNVSKIKNLKLGYLTQQmtlnsnatv 83
Cdd:PRK15064 320 LEVENLTKGFDNGPLFKNLNLLLEAGERLAIIGENGVGKTTLLRTLVGELEPDSGTVKWSENANIGYYAQD--------- 390
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 84 feemskpfehikrmeslikeetdwlskHANDYDSDtykthMSRYESLSnQFEQlEGYQyESKIKTVLHGLNFSEEDFNKP 163
Cdd:PRK15064 391 ---------------------------HAYDFEND-----LTLFDWMS-QWRQ-EGDD-EQAVRGTLGRLLFSQDDIKKS 435
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 164 INDFSGGQKTRLSLAQMLLNEPDLLLLDEPTNHLDLETTKWLEDYLRYFKGAIVIISHDRYFLDKIVTQIYDVALGDVKR 243
Cdd:PRK15064 436 VKVLSGGEKGRMLFGKLMMQKPNVLVMDEPTNHMDMESIESLNMALEKYEGTLIFVSHDREFVSSLATRIIEITPDGVVD 515
|
250
....*....|..
gi 446524717 244 YVGNYEEFIQQR 255
Cdd:PRK15064 516 FSGTYEEYLRSQ 527
|
|
| ZnuC |
COG1121 |
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism]; ... |
330-543 |
1.35e-30 |
|
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440738 [Multi-domain] Cd Length: 245 Bit Score: 120.19 E-value: 1.35e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 330 VMHVKNLEIGY-QTAITKPISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITFG------ANLQIGYYDQkQA 402
Cdd:COG1121 6 AIELENLTVSYgGRPVLEDVSLTIPPGEFVAIVGPNGAGKSTLLKAILGLLPPTSGTVRLFgkpprrARRRIGYVPQ-RA 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 403 EFKSSK--TILDYV----WDQYPLM---NEKD---IRAVLGRflfV--QDDVKKIINDLSGGEKARLQLALLMLQRDNVL 468
Cdd:COG1121 85 EVDWDFpiTVRDVVlmgrYGRRGLFrrpSRADreaVDEALER---VglEDLADRPIGELSGGQQQRVLLARALAQDPDLL 161
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446524717 469 ILDEPTNHLDIDSKEMLEQALQHF--EG-TILFVSHDRYFINQLANKVfdLTIDGGKMYLGDyqyyIEKVEEAEALKA 543
Cdd:COG1121 162 LLDEPFAGVDAATEEALYELLRELrrEGkTILVVTHDLGAVREYFDRV--LLLNRGLVAHGP----PEEVLTPENLSR 233
|
|
| FepC |
COG1120 |
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion ... |
330-510 |
1.45e-30 |
|
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion transport and metabolism, Coenzyme transport and metabolism];
Pssm-ID: 440737 [Multi-domain] Cd Length: 254 Bit Score: 120.53 E-value: 1.45e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 330 VMHVKNLEIGY-QTAITKPISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITF-GANL----------QIGYY 397
Cdd:COG1120 1 MLEAENLSVGYgGRPVLDDVSLSLPPGEVTALLGPNGSGKSTLLRALAGLLKPSSGEVLLdGRDLaslsrrelarRIAYV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 398 DQkQAEFKSSKTILDYV----------WDQyplMNEKDIRAV------LGrflfVQDDVKKIINDLSGGEKARLQLALLM 461
Cdd:COG1120 81 PQ-EPPAPFGLTVRELValgryphlglFGR---PSAEDREAVeealerTG----LEHLADRPVDELSGGERQRVLIARAL 152
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 446524717 462 LQRDNVLILDEPTNHLDIDSK-EMLE--QALQHFEG-TILFVSHDryfINQLA 510
Cdd:COG1120 153 AQEPPLLLLDEPTSHLDLAHQlEVLEllRRLARERGrTVVMVLHD---LNLAA 202
|
|
| ABC_Iron-Siderophores_B12_Hemin |
cd03214 |
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related ... |
333-524 |
5.48e-30 |
|
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; ABC transporters, involved in the uptake of siderophores, heme, and vitamin B12, are widely conserved in bacteria and archaea. Only very few species lack representatives of the siderophore family transporters. The E. coli BtuCD protein is an ABC transporter mediating vitamin B12 uptake. The two ATP-binding cassettes (BtuD) are in close contact with each other, as are the two membrane-spanning subunits (BtuC); this arrangement is distinct from that observed for the E. coli lipid flippase MsbA. The BtuC subunits provide 20 transmembrane helices grouped around a translocation pathway that is closed to the cytoplasm by a gate region, whereas the dimer arrangement of the BtuD subunits resembles the ATP-bound form of the Rad50 DNA repair enzyme. A prominent cytoplasmic loop of BtuC forms the contact region with the ATP-binding cassette and represent a conserved motif among the ABC transporters.
Pssm-ID: 213181 [Multi-domain] Cd Length: 180 Bit Score: 116.38 E-value: 5.48e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 333 VKNLEIGY-QTAITKPISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITFGaNLQIGYYDQKQAefksSKTIL 411
Cdd:cd03214 2 VENLSVGYgGRTVLDDLSLSIEAGEIVGILGPNGAGKSTLLKTLAGLLKPSSGEILLD-GKDLASLSPKEL----ARKIA 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 412 dYVWdQypLMNEKDIRAVLGRFlfvqddvkkiINDLSGGEKARLQLALLMLQRDNVLILDEPTNHLDIDSK-EMLE--QA 488
Cdd:cd03214 77 -YVP-Q--ALELLGLAHLADRP----------FNELSGGERQRVLLARALAQEPPILLLDEPTSHLDIAHQiELLEllRR 142
|
170 180 190
....*....|....*....|....*....|....*....
gi 446524717 489 LQHFEG-TILFVSHDryfINqLANKVFD--LTIDGGKMY 524
Cdd:cd03214 143 LARERGkTVVMVLHD---LN-LAARYADrvILLKDGRIV 177
|
|
| NatA |
COG4555 |
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, ... |
3-255 |
1.23e-28 |
|
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, Inorganic ion transport and metabolism];
Pssm-ID: 443618 [Multi-domain] Cd Length: 243 Bit Score: 114.57 E-value: 1.23e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 3 LLQLNHISKSFDGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNVS-----------KIKNlKLGYL 71
Cdd:COG4555 1 MIEVENLSKKYGKVPALKDVSFTAKDGEITGLLGPNGAGKTTLLRMLAGLLKPDSGSILidgedvrkeprEARR-QIGVL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 72 TQQMTLNSNATVFEemskpfehikrmeslikeetdWLSKHANDYDsdtykthmsryeslsnqfeqLEGYQYESKIKTVLH 151
Cdd:COG4555 80 PDERGLYDRLTVRE---------------------NIRYFAELYG--------------------LFDEELKKRIEELIE 118
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 152 GLNFsEEDFNKPINDFSGGQKTRLSLAQMLLNEPDLLLLDEPTNHLDLETTKWLEDYLRYFK--GAIVIIS-HDRYFLDK 228
Cdd:COG4555 119 LLGL-EEFLDRRVGELSTGMKKKVALARALVHDPKVLLLDEPTNGLDVMARRLLREILRALKkeGKTVLFSsHIMQEVEA 197
|
250 260
....*....|....*....|....*..
gi 446524717 229 IVTQIYDVALGDVkRYVGNYEEFIQQR 255
Cdd:COG4555 198 LCDRVVILHKGKV-VAQGSLDELREEI 223
|
|
| ABC_ATPase |
cd00267 |
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large ... |
332-522 |
1.34e-27 |
|
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213179 [Multi-domain] Cd Length: 157 Bit Score: 108.87 E-value: 1.34e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 332 HVKNLEIGYQT-AITKPISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITF-GANLqigyydqkqaefksskt 409
Cdd:cd00267 1 EIENLSFRYGGrTALDNVSLTLKAGEIVALVGPNGSGKSTLLRAIAGLLKPTSGEILIdGKDI----------------- 63
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 410 ildyvwdqyplmNEKDIRAVLGRFLFV-QddvkkiindLSGGEKARLQLALLMLQRDNVLILDEPTNHLDIDSKEMLEQA 488
Cdd:cd00267 64 ------------AKLPLEELRRRIGYVpQ---------LSGGQRQRVALARALLLNPDLLLLDEPTSGLDPASRERLLEL 122
|
170 180 190
....*....|....*....|....*....|....*..
gi 446524717 489 LQHF--EG-TILFVSHDRYFINQLANKVfdLTIDGGK 522
Cdd:cd00267 123 LRELaeEGrTVIIVTHDPELAELAADRV--IVLKDGK 157
|
|
| GsiA |
COG1123 |
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ... |
3-513 |
4.50e-26 |
|
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440740 [Multi-domain] Cd Length: 514 Bit Score: 112.30 E-value: 4.50e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 3 LLQLNHISKSFDGEDIFT--DVDFEVKTGERIGIVGRNGAGKSTLMKIIAG-------------VENYDSGNVS-KIKNL 66
Cdd:COG1123 4 LLEVRDLSVRYPGGDVPAvdGVSLTIAPGETVALVGESGSGKSTLALALMGllphggrisgevlLDGRDLLELSeALRGR 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 67 KLGYLTQQ-MTLNSNATVFEEMSKPFEHIKRMESLIKEETDWLskhandydsdtykthmsryeslsnqFEQLegyqyesk 145
Cdd:COG1123 84 RIGMVFQDpMTQLNPVTVGDQIAEALENLGLSRAEARARVLEL-------------------------LEAV-------- 130
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 146 iktvlhGLnfsEEDFNKPINDFSGGQKTRLSLAQMLLNEPDLLLLDEPTNHLDLETTKWLEDYLRYFKG----AIVIISH 221
Cdd:COG1123 131 ------GL---ERRLDRYPHQLSGGQRQRVAIAMALALDPDLLIADEPTTALDVTTQAEILDLLRELQRergtTVLLITH 201
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 222 DryfldkivtqiydvaLGDVKRYVgnyeefiqQRDLY-YQKRMQEYESQQAeikrletfVEKNITRASTSGMAKSRRKIL 300
Cdd:COG1123 202 D---------------LGVVAEIA--------DRVVVmDDGRIVEDGPPEE--------ILAAPQALAAVPRLGAARGRA 250
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 301 EKMERIDKPMLDAKsaNIQFGFDRNTGNDVMHVKNleigyqtaitkpISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQK 380
Cdd:COG1123 251 APAAAAAEPLLEVR--NLSKRYPVRGKGGVRAVDD------------VSLTLRRGETLGLVGESGSGKSTLARLLLGLLR 316
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 381 ALNGYITF-GANL-------------QIGY-----YDQkqaeFKSSKTILDYVwdQYPLMN---------EKDIRAVLGR 432
Cdd:COG1123 317 PTSGSILFdGKDLtklsrrslrelrrRVQMvfqdpYSS----LNPRMTVGDII--AEPLRLhgllsraerRERVAELLER 390
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 433 FLFVQDDVKKIINDLSGGEKARLQLA-LLMLQRDnVLILDEPTNHLDIDSK----EMLEQALQHFEGTILFVSHDRYFIN 507
Cdd:COG1123 391 VGLPPDLADRYPHELSGGQRQRVAIArALALEPK-LLILDEPTSALDVSVQaqilNLLRDLQRELGLTYLFISHDLAVVR 469
|
....*.
gi 446524717 508 QLANKV 513
Cdd:COG1123 470 YIADRV 475
|
|
| PRK10636 |
PRK10636 |
putative ABC transporter ATP-binding protein; Provisional |
3-305 |
7.24e-26 |
|
putative ABC transporter ATP-binding protein; Provisional
Pssm-ID: 236729 [Multi-domain] Cd Length: 638 Bit Score: 112.57 E-value: 7.24e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 3 LLQLNHISKSFDGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNVSKIKNLKLGYLTQQMtlnsnat 82
Cdd:PRK10636 312 LLKMEKVSAGYGDRIILDSIKLNLVPGSRIGLLGRNGAGKSTLIKLLAGELAPVSGEIGLAKGIKLGYFAQHQ------- 384
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 83 vfeemskpFEHIKRMESLIKeetdwlskhandydsdtyktHMSRyeslsnqfeqLEGYQYESKIKTVLHGLNFSEEDFNK 162
Cdd:PRK10636 385 --------LEFLRADESPLQ--------------------HLAR----------LAPQELEQKLRDYLGGFGFQGDKVTE 426
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 163 PINDFSGGQKTRLSLAQMLLNEPDLLLLDEPTNHLDLETTKWLEDYLRYFKGAIVIISHDRYFLDKIVTQIYDVALGDVK 242
Cdd:PRK10636 427 ETRRFSGGEKARLVLALIVWQRPNLLLLDEPTNHLDLDMRQALTEALIDFEGALVVVSHDRHLLRSTTDDLYLVHDGKVE 506
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446524717 243 RYVGNYEEFIQ-QRDLYYQKRMQEYESQQAEIKRLETFVEKNITRASTSGMAKSRRKILEKMER 305
Cdd:PRK10636 507 PFDGDLEDYQQwLSDVQKQENQTDEAPKENNANSAQARKDQKRREAELRTQTQPLRKEIARLEK 570
|
|
| ABC_DR_subfamily_A |
cd03230 |
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily ... |
332-523 |
1.37e-25 |
|
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; This family of ATP-binding proteins belongs to a multi-subunit transporter involved in drug resistance (BcrA and DrrA), nodulation, lipid transport, and lantibiotic immunity. In bacteria and archaea, these transporters usually include an ATP-binding protein and one or two integral membrane proteins. Eukaryotic systems of the ABCA subfamily display ABC domains that are quite similar to this family. The ATP-binding domain shows the highest similarity between all members of the ABC transporter family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213197 [Multi-domain] Cd Length: 173 Bit Score: 103.63 E-value: 1.37e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 332 HVKNLEIGY-QTAITKPISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYIT-FGANLQigyydqkqAEFKSSKT 409
Cdd:cd03230 2 EVRNLSKRYgKKTALDDISLTVEKGEIYGLLGPNGAGKTTLIKIILGLLKPDSGEIKvLGKDIK--------KEPEEVKR 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 410 ILDYVWDQYPLMNEKDIRAVLgrflfvqddvkkiinDLSGGEKARLQLALLMLQRDNVLILDEPTNHLDIDSKEMLEQAL 489
Cdd:cd03230 74 RIGYLPEEPSLYENLTVRENL---------------KLSGGMKQRLALAQALLHDPELLILDEPTSGLDPESRREFWELL 138
|
170 180 190
....*....|....*....|....*....|....*..
gi 446524717 490 QHF---EGTILFVSHDRYFINQLANKVfdLTIDGGKM 523
Cdd:cd03230 139 RELkkeGKTILLSSHILEEAERLCDRV--AILNNGRI 173
|
|
| PRK11819 |
PRK11819 |
putative ABC transporter ATP-binding protein; Reviewed |
344-561 |
1.62e-25 |
|
putative ABC transporter ATP-binding protein; Reviewed
Pssm-ID: 236992 [Multi-domain] Cd Length: 556 Bit Score: 110.98 E-value: 1.62e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 344 ITKPISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITFGANLQIGYYDQkQAEFKSSKTILDYVWDQYplmne 423
Cdd:PRK11819 22 ILKDISLSFFPGAKIGVLGLNGAGKSTLLRIMAGVDKEFEGEARPAPGIKVGYLPQ-EPQLDPEKTVRENVEEGV----- 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 424 KDIRAVLGRF-----LFVQDDVK-------------KI---------------------------INDLSGGEKARLQLA 458
Cdd:PRK11819 96 AEVKAALDRFneiyaAYAEPDADfdalaaeqgelqeIIdaadawdldsqleiamdalrcppwdakVTKLSGGERRRVALC 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 459 LLMLQRDNVLILDEPTNHLDIDSKEMLEQALQHFEGTILFVSHDRYFINQLANKVfdLTIDGGKM--YLGDYQYYIEKVE 536
Cdd:PRK11819 176 RLLLEKPDMLLLDEPTNHLDAESVAWLEQFLHDYPGTVVAVTHDRYFLDNVAGWI--LELDRGRGipWEGNYSSWLEQKA 253
|
250 260
....*....|....*....|....*
gi 446524717 537 EAEALKAHQEEqsvnvqAHEKSMEQ 561
Cdd:PRK11819 254 KRLAQEEKQEA------ARQKALKR 272
|
|
| FetA |
COG4619 |
ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism]; |
4-237 |
2.24e-25 |
|
ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443661 [Multi-domain] Cd Length: 209 Bit Score: 104.13 E-value: 2.24e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 4 LQLNHISKSFDGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNVskiknlklgyltqqmTLNSNAtv 83
Cdd:COG4619 1 LELEGLSFRVGGKPILSPVSLTLEAGECVAITGPSGSGKSTLLRALADLDPPTSGEI---------------YLDGKP-- 63
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 84 FEEMskPFEHIKRMESLIKEETDWLSkhandydsDTYKTHMSRYESLSNQFEQLEgyqyesKIKTVLHGLNFSEEDFNKP 163
Cdd:COG4619 64 LSAM--PPPEWRRQVAYVPQEPALWG--------GTVRDNLPFPFQLRERKFDRE------RALELLERLGLPPDILDKP 127
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446524717 164 INDFSGGQKTRLSLAQMLLNEPDLLLLDEPTNHLDLETT----KWLEDYLRYFKGAIVIISHDRYFLDKIVTQIYDVA 237
Cdd:COG4619 128 VERLSGGERQRLALIRALLLQPDVLLLDEPTSALDPENTrrveELLREYLAEEGRAVLWVSHDPEQIERVADRVLTLE 205
|
|
| ABC_Metallic_Cations |
cd03235 |
ATP-binding cassette domain of the metal-type transporters; This family includes transporters ... |
332-502 |
2.43e-25 |
|
ATP-binding cassette domain of the metal-type transporters; This family includes transporters involved in the uptake of various metallic cations such as iron, manganese, and zinc. The ATPases of this group of transporters are very similar to members of iron-siderophore uptake family suggesting that they share a common ancestor. The best characterized metal-type ABC transporters are the YfeABCD system of Y. pestis, the SitABCD system of Salmonella enterica serovar Typhimurium, and the SitABCD transporter of Shigella flexneri. Moreover other uncharacterized homologs of these metal-type transporters are mainly found in pathogens like Haemophilus or enteroinvasive E. coli isolates.
Pssm-ID: 213202 [Multi-domain] Cd Length: 213 Bit Score: 104.15 E-value: 2.43e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 332 HVKNLEIGY-QTAITKPISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYIT-FGANL-----QIGYYDQK-QAE 403
Cdd:cd03235 1 EVEDLTVSYgGHPVLEDVSFEVKPGEFLAIVGPNGAGKSTLLKAILGLLKPTSGSIRvFGKPLekerkRIGYVPQRrSID 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 404 FKSSKTILDYV----WDQYPL---MNEKDIRAVLGRFLFVQ--DDVKKIINDLSGGEKARLQLALLMLQRDNVLILDEPT 474
Cdd:cd03235 81 RDFPISVRDVVlmglYGHKGLfrrLSKADKAKVDEALERVGlsELADRQIGELSGGQQQRVLLARALVQDPDLLLLDEPF 160
|
170 180 190
....*....|....*....|....*....|.
gi 446524717 475 NHLDIDSKEMLEQALQ--HFEG-TILFVSHD 502
Cdd:cd03235 161 AGVDPKTQEDIYELLRelRREGmTILVVTHD 191
|
|
| ABC_cobalt_CbiO_domain1 |
cd03225 |
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ... |
333-522 |
5.94e-24 |
|
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.
Pssm-ID: 213192 [Multi-domain] Cd Length: 211 Bit Score: 100.23 E-value: 5.94e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 333 VKNLEIGYQTAIT---KPISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITFgANLQIGYYDQKQAEFK---- 405
Cdd:cd03225 2 LKNLSFSYPDGARpalDDISLTIKKGEFVLIVGPNGSGKSTLLRLLNGLLGPTSGEVLV-DGKDLTKLSLKELRRKvglv 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 406 --------SSKTILDYVwdQYPLMN--------EKDIRAVLGRFLFvQDDVKKIINDLSGGEKARLQLALLMLQRDNVLI 469
Cdd:cd03225 81 fqnpddqfFGPTVEEEV--AFGLENlglpeeeiEERVEEALELVGL-EGLRDRSPFTLSGGQKQRVAIAGVLAMDPDILL 157
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 446524717 470 LDEPTNHLDIDSKEMLEQALQHF--EG-TILFVSHDRYFINQLANKVfdLTIDGGK 522
Cdd:cd03225 158 LDEPTAGLDPAGRRELLELLKKLkaEGkTIIIVTHDLDLLLELADRV--IVLEDGK 211
|
|
| ZnuC |
COG1121 |
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism]; ... |
1-230 |
7.39e-24 |
|
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440738 [Multi-domain] Cd Length: 245 Bit Score: 100.93 E-value: 7.39e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 1 MILLQLNHISKSFDGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNVS------KIKNLKLGYLTQQ 74
Cdd:COG1121 4 MPAIELENLTVSYGGRPVLEDVSLTIPPGEFVAIVGPNGAGKSTLLKAILGLLPPTSGTVRlfgkppRRARRRIGYVPQR 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 75 MTLNSN--ATVFE--EMSkpfeHIKRMeSLIKeetdWLSKHANDydsdtykthmsryeslsnqfeqlegyqyesKIKTVL 150
Cdd:COG1121 84 AEVDWDfpITVRDvvLMG----RYGRR-GLFR----RPSRADRE------------------------------AVDEAL 124
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 151 H--GLnfseEDF-NKPINDFSGGQKTRLSLAQ----------MllnepdllllDEPTNHLDLETTKWLEDYLRYFKG--- 214
Cdd:COG1121 125 ErvGL----EDLaDRPIGELSGGQQQRVLLARalaqdpdlllL----------DEPFAGVDAATEEALYELLRELRRegk 190
|
250 260
....*....|....*....|.
gi 446524717 215 AIVIISHD-----RYFlDKIV 230
Cdd:COG1121 191 TILVVTHDlgavrEYF-DRVL 210
|
|
| CcmA |
COG1131 |
ABC-type multidrug transport system, ATPase component [Defense mechanisms]; |
4-220 |
1.47e-23 |
|
ABC-type multidrug transport system, ATPase component [Defense mechanisms];
Pssm-ID: 440746 [Multi-domain] Cd Length: 236 Bit Score: 99.75 E-value: 1.47e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 4 LQLNHISKSFDGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNVS-----------KIKNlKLGYLT 72
Cdd:COG1131 1 IEVRGLTKRYGDKTALDGVSLTVEPGEIFGLLGPNGAGKTTTIRMLLGLLRPTSGEVRvlgedvardpaEVRR-RIGYVP 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 73 QQMTLNSNATVFEEMskpfEHIKRMESLIKEETDwlskhandydsdtykthmSRYESLSNQFEqLEGYQyeskiktvlhg 152
Cdd:COG1131 80 QEPALYPDLTVRENL----RFFARLYGLPRKEAR------------------ERIDELLELFG-LTDAA----------- 125
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 153 lnfseedfNKPINDFSGGQKTRLSLAQ----------MllnepdllllDEPTNHLDLETTKWLEDYLRYFK--GAIVIIS 220
Cdd:COG1131 126 --------DRKVGTLSGGMKQRLGLALallhdpelliL----------DEPTSGLDPEARRELWELLRELAaeGKTVLLS 187
|
|
| CcmA |
COG4133 |
ABC-type transport system involved in cytochrome c biogenesis, ATPase component ... |
330-517 |
1.64e-23 |
|
ABC-type transport system involved in cytochrome c biogenesis, ATPase component [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 443308 [Multi-domain] Cd Length: 206 Bit Score: 98.71 E-value: 1.64e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 330 VMHVKNLEIGY-QTAITKPISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITF-GANL---------QIGYYD 398
Cdd:COG4133 2 MLEAENLSCRRgERLLFSGLSFTLAAGEALALTGPNGSGKTTLLRILAGLLPPSAGEVLWnGEPIrdaredyrrRLAYLG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 399 QkQAEFKSSKTI---LDYVWDQYPL-MNEKDIRAVLGRF-LFVQDDVKkiINDLSGGEKARLQLALLMLQRDNVLILDEP 473
Cdd:COG4133 82 H-ADGLKPELTVrenLRFWAALYGLrADREAIDEALEAVgLAGLADLP--VRQLSAGQKRRVALARLLLSPAPLWLLDEP 158
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 446524717 474 TNHLDIDSKEMLEQALQHF---EGTILFVSHDRYFInqLANKVFDLT 517
Cdd:COG4133 159 FTALDAAGVALLAELIAAHlarGGAVLLTTHQPLEL--AAARVLDLG 203
|
|
| CcmA |
COG1131 |
ABC-type multidrug transport system, ATPase component [Defense mechanisms]; |
332-523 |
1.87e-23 |
|
ABC-type multidrug transport system, ATPase component [Defense mechanisms];
Pssm-ID: 440746 [Multi-domain] Cd Length: 236 Bit Score: 99.37 E-value: 1.87e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 332 HVKNLE--IGYQTAItKPISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYIT-FGANL---------QIGYYDQ 399
Cdd:COG1131 2 EVRGLTkrYGDKTAL-DGVSLTVEPGEIFGLLGPNGAGKTTTIRMLLGLLRPTSGEVRvLGEDVardpaevrrRIGYVPQ 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 400 KQA--EFKSSKTILDYVWDQYPL---MNEKDIRAVLGRF-LfvQDDVKKIINDLSGGEKARLQLALLMLQRDNVLILDEP 473
Cdd:COG1131 81 EPAlyPDLTVRENLRFFARLYGLprkEARERIDELLELFgL--TDAADRKVGTLSGGMKQRLGLALALLHDPELLILDEP 158
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 446524717 474 TNHLDIDSKEMLEQALQHF--EG-TILFVSHDRYFINQLANKVfdLTIDGGKM 523
Cdd:COG1131 159 TSGLDPEARRELWELLRELaaEGkTVLLSTHYLEEAERLCDRV--AIIDKGRI 209
|
|
| ABC_cobalt_CbiO_domain1 |
cd03225 |
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ... |
5-234 |
2.77e-23 |
|
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.
Pssm-ID: 213192 [Multi-domain] Cd Length: 211 Bit Score: 98.31 E-value: 2.77e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 5 QLNHISKSFDGED--IFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNV---------SKIKNL--KLGYL 71
Cdd:cd03225 1 ELKNLSFSYPDGArpALDDISLTIKKGEFVLIVGPNGSGKSTLLRLLNGLLGPTSGEVlvdgkdltkLSLKELrrKVGLV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 72 TQ----QMtlnSNATVFEEMSKPFEHIKRMESLIKEETDWLSKHANdydsdtykthmsryeslsnqfeqLEGYQyeskik 147
Cdd:cd03225 81 FQnpddQF---FGPTVEEEVAFGLENLGLPEEEIEERVEEALELVG-----------------------LEGLR------ 128
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 148 tvlhglnfseedfNKPINDFSGGQKTRLSLAQMLLNEPDLLLLDEPTNHLDLETTKWLEDYLRYFKGA---IVIISHDRY 224
Cdd:cd03225 129 -------------DRSPFTLSGGQKQRVAIAGVLAMDPDILLLDEPTAGLDPAGRRELLELLKKLKAEgktIIIVTHDLD 195
|
250
....*....|
gi 446524717 225 FLDKIVTQIY 234
Cdd:cd03225 196 LLLELADRVI 205
|
|
| met_CoM_red_A2 |
TIGR03269 |
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ... |
4-513 |
5.26e-23 |
|
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]
Pssm-ID: 132313 [Multi-domain] Cd Length: 520 Bit Score: 102.96 E-value: 5.26e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 4 LQLNHISKSFDGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENY--DSGNVskIKNL----KLGYLTQQMTL 77
Cdd:TIGR03269 1 IEVKNLTKKFDGKEVLKNISFTIEEGEVLGILGRSGAGKSVLMHVLRGMDQYepTSGRI--IYHValceKCGYVERPSKV 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 78 NSNATVFEEMSKPFE------------HIKRMESLIKEETDWLskhandYDSDTYkthmsryesLSNQFEQLEGYQYESK 145
Cdd:TIGR03269 79 GEPCPVCGGTLEPEEvdfwnlsdklrrRIRKRIAIMLQRTFAL------YGDDTV---------LDNVLEALEEIGYEGK 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 146 iKTVLHGLNFSEE-----DFNKPINDFSGGQKTRLSLAQMLLNEPDLLLLDEPTNHLDLETTKWLEDYLRyfKGAI---- 216
Cdd:TIGR03269 144 -EAVGRAVDLIEMvqlshRITHIARDLSGGEKQRVVLARQLAKEPFLFLADEPTGTLDPQTAKLVHNALE--EAVKasgi 220
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 217 --VIISHDRYFLDKIVTQIYDVALGDVKRyVGNYEEFIQqrdlyyqkrmqeyesqqaeiKRLETFVEknitrastsgmak 294
Cdd:TIGR03269 221 smVLTSHWPEVIEDLSDKAIWLENGEIKE-EGTPDEVVA--------------------VFMEGVSE------------- 266
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 295 srrkiLEKMERIDkpmldaksaniqfgfdrnTGNDVMHVKNLEIGY---QTAITKP---ISIEVSKGDHIAIIGPNGIGK 368
Cdd:TIGR03269 267 -----VEKECEVE------------------VGEPIIKVRNVSKRYisvDRGVVKAvdnVSLEVKEGEIFGIVGTSGAGK 323
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 369 STLIKTIANQQKALNG--YITFG----------------ANLQIGYYDQKQAEFkSSKTILDYVWDQYPLMNEKDI---R 427
Cdd:TIGR03269 324 TTLSKIIAGVLEPTSGevNVRVGdewvdmtkpgpdgrgrAKRYIGILHQEYDLY-PHRTVLDNLTEAIGLELPDELarmK 402
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 428 AV--LGRFLFVQDDVKKIIN----DLSGGEKARLQLALLMLQRDNVLILDEPTNHLD----IDSKEMLEQALQHFEGTIL 497
Cdd:TIGR03269 403 AVitLKMVGFDEEKAEEILDkypdELSEGERHRVALAQVLIKEPRIVILDEPTGTMDpitkVDVTHSILKAREEMEQTFI 482
|
570
....*....|....*.
gi 446524717 498 FVSHDRYFINQLANKV 513
Cdd:TIGR03269 483 IVSHDMDFVLDVCDRA 498
|
|
| ABCC_MRP_Like |
cd03228 |
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP ... |
331-522 |
5.29e-23 |
|
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP (Multidrug Resistance Protein)-like transporters are involved in drug, peptide, and lipid export. They belong to the subfamily C of the ATP-binding cassette (ABC) superfamily of transport proteins. The ABCC subfamily contains transporters with a diverse functional spectrum that includes ion transport, cell surface receptor, and toxin secretion activities. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains, each composed of six transmembrane (TM) helices, and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213195 [Multi-domain] Cd Length: 171 Bit Score: 96.30 E-value: 5.29e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 331 MHVKNLEIGYQTA---ITKPISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITfganlqIGYYDQKQAEFKSS 407
Cdd:cd03228 1 IEFKNVSFSYPGRpkpVLKDVSLTIKPGEKVAIVGPSGSGKSTLLKLLLRLYDPTSGEIL------IDGVDLRDLDLESL 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 408 KTILDYVwDQYPlmnekdiravlgrFLFvQDDVKKiiNDLSGGEKARLQLALLMLQRDNVLILDEPTNHLDIDSKEMLEQ 487
Cdd:cd03228 75 RKNIAYV-PQDP-------------FLF-SGTIRE--NILSGGQRQRIAIARALLRDPPILILDEATSALDPETEALILE 137
|
170 180 190
....*....|....*....|....*....|....*..
gi 446524717 488 ALQHFEG--TILFVSHdRYFINQLANKVFDLtiDGGK 522
Cdd:cd03228 138 ALRALAKgkTVIVIAH-RLSTIRDADRIIVL--DDGR 171
|
|
| NatA |
COG4555 |
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, ... |
333-523 |
1.13e-22 |
|
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, Inorganic ion transport and metabolism];
Pssm-ID: 443618 [Multi-domain] Cd Length: 243 Bit Score: 97.24 E-value: 1.13e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 333 VKNLEIGYQ-TAITKPISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITF----------GANLQIGYYDQKQ 401
Cdd:COG4555 4 VENLSKKYGkVPALKDVSFTAKDGEITGLLGPNGAGKTTLLRMLAGLLKPDSGSILIdgedvrkeprEARRQIGVLPDER 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 402 A--EFKSSKTILDYVWDQYPLM---NEKDIRAVLGRFLFvQDDVKKIINDLSGGEKARLQLALLMLQRDNVLILDEPTNH 476
Cdd:COG4555 84 GlyDRLTVRENIRYFAELYGLFdeeLKKRIEELIELLGL-EEFLDRRVGELSTGMKKKVALARALVHDPKVLLLDEPTNG 162
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 446524717 477 LDIDSKEMLEQALQHF---EGTILFVSHDRYFINQLANKVfdLTIDGGKM 523
Cdd:COG4555 163 LDVMARRLLREILRALkkeGKTVLFSSHIMQEVEALCDRV--VILHKGKV 210
|
|
| CcmA |
COG4133 |
ABC-type transport system involved in cytochrome c biogenesis, ATPase component ... |
3-227 |
1.39e-22 |
|
ABC-type transport system involved in cytochrome c biogenesis, ATPase component [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 443308 [Multi-domain] Cd Length: 206 Bit Score: 96.01 E-value: 1.39e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 3 LLQLNHISKSFDGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNVskiknlklgYLTQQMTLNSNAT 82
Cdd:COG4133 2 MLEAENLSCRRGERLLFSGLSFTLAAGEALALTGPNGSGKTTLLRILAGLLPPSAGEV---------LWNGEPIRDARED 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 83 VFEEMSkpfehikrmeslikeetdWLSkHANDydsdtYKTHMSRYESLSNQFEQLEGYQYESKIKTVLHGLNFSE-EDfn 161
Cdd:COG4133 73 YRRRLA------------------YLG-HADG-----LKPELTVRENLRFWAALYGLRADREAIDEALEAVGLAGlAD-- 126
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446524717 162 KPINDFSGGQKTRLSLAQ----------MllnepdllllDEPTNHLDLETTKWLEDYLRYFK---GAIVIISHDRYFLD 227
Cdd:COG4133 127 LPVRQLSAGQKRRVALARlllspaplwlL----------DEPFTALDAAGVALLAELIAAHLargGAVLLTTHQPLELA 195
|
|
| SunT |
COG2274 |
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase ... |
332-523 |
1.90e-22 |
|
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms];
Pssm-ID: 441875 [Multi-domain] Cd Length: 711 Bit Score: 102.22 E-value: 1.90e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 332 HVKNLEIGY---QTAITKPISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITF-GANL----------QIGYY 397
Cdd:COG2274 475 ELENVSFRYpgdSPPVLDNISLTIKPGERVAIVGRSGSGKSTLLKLLLGLYEPTSGRILIdGIDLrqidpaslrrQIGVV 554
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 398 DQKQAEFksSKTILD--YVWDqyPLMNEKDIRAVLgRFLFVQDDVKK-------IIND----LSGGEKARLQLALLMLQR 464
Cdd:COG2274 555 LQDVFLF--SGTIREniTLGD--PDATDEEIIEAA-RLAGLHDFIEAlpmgydtVVGEggsnLSGGQRQRLAIARALLRN 629
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446524717 465 DNVLILDEPTNHLDIDSKEMLEQALQHFEG--TILFVSHDRYFInQLANKVfdLTIDGGKM 523
Cdd:COG2274 630 PRILILDEATSALDAETEAIILENLRRLLKgrTVIIIAHRLSTI-RLADRI--IVLDKGRI 687
|
|
| ABC_tran_Xtn |
pfam12848 |
ABC transporter; This domain is an extension of some members of pfam00005 and other ... |
234-320 |
1.95e-22 |
|
ABC transporter; This domain is an extension of some members of pfam00005 and other ABC-transporter families.
Pssm-ID: 463731 [Multi-domain] Cd Length: 85 Bit Score: 91.48 E-value: 1.95e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 234 YDVALGDVKRYVGNYEEFIQQRDLYYQKRMQEYESQQAEIKRLETFVEKNITRASTSGMAKSRRKILEKMERIDKPmlDA 313
Cdd:pfam12848 1 VELERGKLTTYKGNYSTFLEQKEERLEQQEKAYEKQQKEIKKLEEFIDRFRAKASKAKQAQSRIKALEKMERIEKP--ER 78
|
....*..
gi 446524717 314 KSANIQF 320
Cdd:pfam12848 79 DKPKLRF 85
|
|
| ABC_DR_subfamily_A |
cd03230 |
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily ... |
4-234 |
3.36e-22 |
|
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; This family of ATP-binding proteins belongs to a multi-subunit transporter involved in drug resistance (BcrA and DrrA), nodulation, lipid transport, and lantibiotic immunity. In bacteria and archaea, these transporters usually include an ATP-binding protein and one or two integral membrane proteins. Eukaryotic systems of the ABCA subfamily display ABC domains that are quite similar to this family. The ATP-binding domain shows the highest similarity between all members of the ABC transporter family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213197 [Multi-domain] Cd Length: 173 Bit Score: 94.00 E-value: 3.36e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 4 LQLNHISKSFDGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNVskiknlklgyltqqmtlnsnaTV 83
Cdd:cd03230 1 IEVRNLSKRYGKKTALDDISLTVEKGEIYGLLGPNGAGKTTLIKIILGLLKPDSGEI---------------------KV 59
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 84 FEemskpfEHIKRMESLIKEETDWLSKHANDYDsdtyktHMSRYESLsnqfeqlegyqyeskiktvlhglnfseedfnkp 163
Cdd:cd03230 60 LG------KDIKKEPEEVKRRIGYLPEEPSLYE------NLTVRENL--------------------------------- 94
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446524717 164 inDFSGGQKTRLSLAQMLLNEPDLLLLDEPTNHLDLETTKWLEDYLRYFK---GAIVIISHDRYFLDKIVTQIY 234
Cdd:cd03230 95 --KLSGGMKQRLALAQALLHDPELLILDEPTSGLDPESRREFWELLRELKkegKTILLSSHILEEAERLCDRVA 166
|
|
| ABC_tran |
pfam00005 |
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ... |
346-475 |
4.95e-22 |
|
ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.
Pssm-ID: 394964 [Multi-domain] Cd Length: 150 Bit Score: 92.71 E-value: 4.95e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 346 KPISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITFG-----------ANLQIGYYDQKqAEFKSSKTILDYV 414
Cdd:pfam00005 2 KNVSLTLNPGEILALVGPNGAGKSTLLKLIAGLLSPTEGTILLDgqdltdderksLRKEIGYVFQD-PQLFPRLTVRENL 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 415 WD-------QYPLMNEK--DIRAVLGRFLFVQDDVKKIINDLSGGEKARLQLALLMLQRDNVLILDEPTN 475
Cdd:pfam00005 81 RLglllkglSKREKDARaeEALEKLGLGDLADRPVGERPGTLSGGQRQRVAIARALLTKPKLLLLDEPTA 150
|
|
| FepC |
COG1120 |
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion ... |
3-230 |
1.77e-21 |
|
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion transport and metabolism, Coenzyme transport and metabolism];
Pssm-ID: 440737 [Multi-domain] Cd Length: 254 Bit Score: 94.34 E-value: 1.77e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 3 LLQLNHISKSFDGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNVS----KIKNL-------KLGYL 71
Cdd:COG1120 1 MLEAENLSVGYGGRPVLDDVSLSLPPGEVTALLGPNGSGKSTLLRALAGLLKPSSGEVLldgrDLASLsrrelarRIAYV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 72 TQQMTLNSNATVFE--EMSKpFEHIKRMESLIKEetdwlskhanDYDsdtykthmsryeslsnqfeqlegyqyesKIKTV 149
Cdd:COG1120 81 PQEPPAPFGLTVRElvALGR-YPHLGLFGRPSAE----------DRE----------------------------AVEEA 121
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 150 LH--GLnfseEDF-NKPINDFSGGQKTRLSLAQ----------MllnepdllllDEPTNHLDL----ETTKWLEDYLRYF 212
Cdd:COG1120 122 LErtGL----EHLaDRPVDELSGGERQRVLIARalaqepplllL----------DEPTSHLDLahqlEVLELLRRLARER 187
|
250 260
....*....|....*....|...
gi 446524717 213 KGAIVIISHD-----RYFlDKIV 230
Cdd:COG1120 188 GRTVVMVLHDlnlaaRYA-DRLV 209
|
|
| ABC_BcrA_bacitracin_resist |
cd03268 |
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily ... |
4-233 |
3.67e-21 |
|
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily represents ABC transporters involved in peptide antibiotic resistance. Bacitracin is a dodecapeptide antibiotic produced by B. licheniformis and B. subtilis. The synthesis of bacitracin is non-ribosomally catalyzed by a multi-enzyme complex BcrABC. Bacitracin has potent antibiotic activity against gram-positive bacteria. The inhibition of peptidoglycan biosynthesis is the best characterized bacterial effect of bacitracin. The bacitracin resistance of B. licheniformis is mediated by the ABC transporter Bcr which is composed of two identical BcrA ATP-binding subunits and one each of the integral membrane proteins, BcrB and BcrC. B. subtilis cells carrying bcr genes on high-copy number plasmids develop collateral detergent sensitivity, a similar phenomenon in human cells with overexpressed multi-drug resistance P-glycoprotein.
Pssm-ID: 213235 [Multi-domain] Cd Length: 208 Bit Score: 91.89 E-value: 3.67e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 4 LQLNHISKSFDGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNVskiknlklgyltqqmtlnsnaTV 83
Cdd:cd03268 1 LKTNDLTKTYGKKRVLDDISLHVKKGEIYGFLGPNGAGKTTTMKIILGLIKPDSGEI---------------------TF 59
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 84 F-EEMSKPFEHIKRMESLIkeetdwlskhandyDSDTYKTHMSRYESLSNqFEQLEGYQYEsKIKTVLHGLNFSEEDfNK 162
Cdd:cd03268 60 DgKSYQKNIEALRRIGALI--------------EAPGFYPNLTARENLRL-LARLLGIRKK-RIDEVLDVVGLKDSA-KK 122
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446524717 163 PINDFSGGQKTRLSLAQMLLNEPDLLLLDEPTNHLDLETTKWLEDYLRYFK---GAIVIISHDRYFLDKIVTQI 233
Cdd:cd03268 123 KVKGFSLGMKQRLGIALALLGNPDLLILDEPTNGLDPDGIKELRELILSLRdqgITVLISSHLLSEIQKVADRI 196
|
|
| CydD |
COG4988 |
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease ... |
326-522 |
3.19e-20 |
|
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444012 [Multi-domain] Cd Length: 563 Bit Score: 94.82 E-value: 3.19e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 326 TGNDVMHVKNLEIGYQ--TAITKPISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITF-GANL---------- 392
Cdd:COG4988 332 AGPPSIELEDVSFSYPggRPALDGLSLTIPPGERVALVGPSGAGKSTLLNLLLGFLPPYSGSILInGVDLsdldpaswrr 411
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 393 QIGYYDQKQAEFKSskTILDYVWDQYPLMNEKDIRAVLGRfLFVQDDVKK-------IIND----LSGGEKARLQLALLM 461
Cdd:COG4988 412 QIAWVPQNPYLFAG--TIRENLRLGRPDASDEELEAALEA-AGLDEFVAAlpdgldtPLGEggrgLSGGQAQRLALARAL 488
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446524717 462 LQRDNVLILDEPTNHLDIDSKEMLEQALQH-FEG-TILFVSHDRYFINQlANKVFDLtiDGGK 522
Cdd:COG4988 489 LRDAPLLLLDEPTAHLDAETEAEILQALRRlAKGrTVILITHRLALLAQ-ADRILVL--DDGR 548
|
|
| ABCC_cytochrome_bd |
cd03247 |
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome ... |
333-501 |
9.98e-20 |
|
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome bd biogenesis. The CydC and CydD proteins are important for the formation of cytochrome bd terminal oxidase of E. coli and it has been proposed that they were necessary for biosynthesis of the cytochrome bd quinol oxidase and for periplasmic c-type cytochromes. CydCD were proposed to determine a heterooligomeric complex important for heme export into the periplasm or to be involved in the maintenance of the proper redox state of the periplasmic space. In Bacillus subtilis, the absence of CydCD does not affect the presence of halo-cytochrome c in the membrane and this observation suggests that CydCD proteins are not involved in the export of heme in this organism.
Pssm-ID: 213214 [Multi-domain] Cd Length: 178 Bit Score: 86.98 E-value: 9.98e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 333 VKNLEIGY---QTAITKPISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITFGANLQIGYYDQKqaefksSKT 409
Cdd:cd03247 3 INNVSFSYpeqEQQVLKNLSLELKQGEKIALLGRSGSGKSTLLQLLTGDLKPQQGEITLDGVPVSDLEKAL------SSL 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 410 IldYVWDQYPLMNEKDIRAVLGRflfvqddvkkiinDLSGGEKARLQLALLMLQRDNVLILDEPTNHLD-IDSKEMLEQA 488
Cdd:cd03247 77 I--SVLNQRPYLFDTTLRNNLGR-------------RFSGGERQRLALARILLQDAPIVLLDEPTVGLDpITERQLLSLI 141
|
170
....*....|....
gi 446524717 489 LQHFEG-TILFVSH 501
Cdd:cd03247 142 FEVLKDkTLIWITH 155
|
|
| EcfA2 |
COG1122 |
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and ... |
333-523 |
1.55e-19 |
|
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and metabolism, General function prediction only];
Pssm-ID: 440739 [Multi-domain] Cd Length: 230 Bit Score: 87.77 E-value: 1.55e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 333 VKNLEIGYQTAIT--KPISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITFGanlqigyydqkqaefksSKTI 410
Cdd:COG1122 3 LENLSFSYPGGTPalDDVSLSIEKGEFVAIIGPNGSGKSTLLRLLNGLLKPTSGEVLVD-----------------GKDI 65
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 411 LDYvwdqyplmNEKDIRAVLGrFLF-----------VQDDV-------------------------------KKIINDLS 448
Cdd:COG1122 66 TKK--------NLRELRRKVG-LVFqnpddqlfaptVEEDVafgpenlglpreeirerveealelvglehlaDRPPHELS 136
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446524717 449 GGEKARLQLA-LLMLQRDnVLILDEPTNHLDIDSKEMLEQALQ--HFEG-TILFVSHDRYFINQLANKVfdLTIDGGKM 523
Cdd:COG1122 137 GGQKQRVAIAgVLAMEPE-VLVLDEPTAGLDPRGRRELLELLKrlNKEGkTVIIVTHDLDLVAELADRV--IVLDDGRI 212
|
|
| CydC |
COG4987 |
ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease ... |
333-502 |
2.18e-19 |
|
ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444011 [Multi-domain] Cd Length: 569 Bit Score: 92.14 E-value: 2.18e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 333 VKNLEIGY---QTAITKPISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITFG---------ANL--QIGYYD 398
Cdd:COG4987 336 LEDVSFRYpgaGRPVLDGLSLTLPPGERVAIVGPSGSGKSTLLALLLRFLDPQSGSITLGgvdlrdldeDDLrrRIAVVP 415
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 399 QKQAEFksSKTILDyvwdqyplmN---------EKDIRAVLGRflfVQ--DDVKKIINDL-----------SGGEKARLQ 456
Cdd:COG4987 416 QRPHLF--DTTLRE---------NlrlarpdatDEELWAALER---VGlgDWLAALPDGLdtwlgeggrrlSGGERRRLA 481
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 446524717 457 LALLMLQRDNVLILDEPTNHLDIDS-KEMLEQALQHFEG-TILFVSHD 502
Cdd:COG4987 482 LARALLRDAPILLLDEPTEGLDAATeQALLADLLEALAGrTVLLITHR 529
|
|
| ABC_tran |
pfam00005 |
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ... |
19-195 |
2.36e-19 |
|
ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.
Pssm-ID: 394964 [Multi-domain] Cd Length: 150 Bit Score: 85.01 E-value: 2.36e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 19 FTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNVS-----------KIKNLKLGYLTQQMTLNSNATVFEEM 87
Cdd:pfam00005 1 LKNVSLTLNPGEILALVGPNGAGKSTLLKLIAGLLSPTEGTILldgqdltdderKSLRKEIGYVFQDPQLFPRLTVRENL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 88 SKPFEHIKRMESLIKEETDWLSKHANDYDsdtykthmsryeslsnqfeqlegyqyesKIKTVLHglnfseedfnKPINDF 167
Cdd:pfam00005 81 RLGLLLKGLSKREKDARAEEALEKLGLGD----------------------------LADRPVG----------ERPGTL 122
|
170 180
....*....|....*....|....*...
gi 446524717 168 SGGQKTRLSLAQMLLNEPDLLLLDEPTN 195
Cdd:pfam00005 123 SGGQRQRVAIARALLTKPKLLLLDEPTA 150
|
|
| ModF |
COG1119 |
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA ... |
342-501 |
2.87e-19 |
|
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA [Inorganic ion transport and metabolism];
Pssm-ID: 440736 [Multi-domain] Cd Length: 250 Bit Score: 87.83 E-value: 2.87e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 342 TAITKPISIEVSKGDHIAIIGPNGIGKSTLIKTIanqqkalNGYI--TFGANL-----------------QIGYYDQK-Q 401
Cdd:COG1119 16 KTILDDISWTVKPGEHWAILGPNGAGKSTLLSLI-------TGDLppTYGNDVrlfgerrggedvwelrkRIGLVSPAlQ 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 402 AEFKSSKTILDYV----------WDQYPLMNEKDIRAVLgRFLFVQDDVKKIINDLSGGEKARLQLALLMLQRDNVLILD 471
Cdd:COG1119 89 LRFPRDETVLDVVlsgffdsiglYREPTDEQRERARELL-ELLGLAHLADRPFGTLSQGEQRRVLIARALVKDPELLILD 167
|
170 180 190
....*....|....*....|....*....|....
gi 446524717 472 EPTNHLDIDSKEMLEQALQHF--EG--TILFVSH 501
Cdd:COG1119 168 EPTAGLDLGARELLLALLDKLaaEGapTLVLVTH 201
|
|
| ABC_BcrA_bacitracin_resist |
cd03268 |
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily ... |
348-523 |
5.66e-19 |
|
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily represents ABC transporters involved in peptide antibiotic resistance. Bacitracin is a dodecapeptide antibiotic produced by B. licheniformis and B. subtilis. The synthesis of bacitracin is non-ribosomally catalyzed by a multi-enzyme complex BcrABC. Bacitracin has potent antibiotic activity against gram-positive bacteria. The inhibition of peptidoglycan biosynthesis is the best characterized bacterial effect of bacitracin. The bacitracin resistance of B. licheniformis is mediated by the ABC transporter Bcr which is composed of two identical BcrA ATP-binding subunits and one each of the integral membrane proteins, BcrB and BcrC. B. subtilis cells carrying bcr genes on high-copy number plasmids develop collateral detergent sensitivity, a similar phenomenon in human cells with overexpressed multi-drug resistance P-glycoprotein.
Pssm-ID: 213235 [Multi-domain] Cd Length: 208 Bit Score: 85.73 E-value: 5.66e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 348 ISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITFganLQIGYYDQKQAeFKSSKTILDYVW------------ 415
Cdd:cd03268 19 ISLHVKKGEIYGFLGPNGAGKTTTMKIILGLIKPDSGEITF---DGKSYQKNIEA-LRRIGALIEAPGfypnltarenlr 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 416 --DQYPLMNEKDIRAVLGRFLFvQDDVKKIINDLSGGEKARLQLALLMLQRDNVLILDEPTNHLDIDS-KEMLE--QALQ 490
Cdd:cd03268 95 llARLLGIRKKRIDEVLDVVGL-KDSAKKKVKGFSLGMKQRLGIALALLGNPDLLILDEPTNGLDPDGiKELREliLSLR 173
|
170 180 190
....*....|....*....|....*....|...
gi 446524717 491 HFEGTILFVSHDRYFINQLANKVfdLTIDGGKM 523
Cdd:cd03268 174 DQGITVLISSHLLSEIQKVADRI--GIINKGKL 204
|
|
| ABCD_peroxisomal_ALDP |
cd03223 |
ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding ... |
342-521 |
1.03e-18 |
|
ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding cassette transporter (Pat) is involved in the import of very long-chain fatty acids (VLCFA) into the peroxisome. The peroxisomal membrane forms a permeability barrier for a wide variety of metabolites required for and formed during fatty acid beta-oxidation. To communicate with the cytoplasm and mitochondria, peroxisomes need dedicated proteins to transport such hydrophilic molecules across their membranes. X-linked adrenoleukodystrophy (X-ALD) is caused by mutations in the ALD gene, which encodes ALDP (adrenoleukodystrophy protein ), a peroxisomal integral membrane protein that is a member of the ATP-binding cassette (ABC) transporter protein family. The disease is characterized by a striking and unpredictable variation in phenotypic expression. Phenotypes include the rapidly progressive childhood cerebral form (CCALD), the milder adult form, adrenomyeloneuropathy (AMN), and variants without neurologic involvement (i.e. asymptomatic).
Pssm-ID: 213190 [Multi-domain] Cd Length: 166 Bit Score: 83.74 E-value: 1.03e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 342 TAITKPISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITFGANLQIGYYDQKqaefkssktildyvwdqyPLM 421
Cdd:cd03223 14 RVLLKDLSFEIKPGDRLLITGPSGTGKSSLFRALAGLWPWGSGRIGMPEGEDLLFLPQR------------------PYL 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 422 NEKDIRAVLgrfLFVQDDVkkiindLSGGEKARLQLALLMLQRDNVLILDEPTNHLDIDSKEMLEQALQHFEGTILFVSH 501
Cdd:cd03223 76 PLGTLREQL---IYPWDDV------LSGGEQQRLAFARLLLHKPKFVFLDEATSALDEESEDRLYQLLKELGITVISVGH 146
|
170 180
....*....|....*....|
gi 446524717 502 dRYFINQLANKVFDLTIDGG 521
Cdd:cd03223 147 -RPSLWKFHDRVLDLDGEGG 165
|
|
| ABC_Class3 |
cd03229 |
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is ... |
331-513 |
1.07e-18 |
|
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is comprised of all BPD (Binding Protein Dependent) systems that are largely represented in archaea and eubacteria and are primarily involved in scavenging solutes from the environment. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213196 [Multi-domain] Cd Length: 178 Bit Score: 84.16 E-value: 1.07e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 331 MHVKNLEIGY-QTAITKPISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITF-GANLQIGYYDQKQAEFKSSk 408
Cdd:cd03229 1 LELKNVSKRYgQKTVLNDVSLNIEAGEIVALLGPSGSGKSTLLRCIAGLEEPDSGSILIdGEDLTDLEDELPPLRRRIG- 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 409 tildYVWDQYPLMNEKDIRavlgrflfvqddvKKIINDLSGGEKARLQLALLMLQRDNVLILDEPTNHLD---IDSKEML 485
Cdd:cd03229 80 ----MVFQDFALFPHLTVL-------------ENIALGLSGGQQQRVALARALAMDPDVLLLDEPTSALDpitRREVRAL 142
|
170 180
....*....|....*....|....*....
gi 446524717 486 EQALQHFEG-TILFVSHDRYFINQLANKV 513
Cdd:cd03229 143 LKSLQAQLGiTVVLVTHDLDEAARLADRV 171
|
|
| ABC_cobalt_CbiO_domain2 |
cd03226 |
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of ... |
332-522 |
1.22e-18 |
|
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. The CbiMNQO family ABC transport system is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.
Pssm-ID: 213193 [Multi-domain] Cd Length: 205 Bit Score: 84.62 E-value: 1.22e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 332 HVKNLEIGY--QTAITKPISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITFGANL--------QIGYYDQK- 400
Cdd:cd03226 1 RIENISFSYkkGTEILDDLSLDLYAGEIIALTGKNGAGKTTLAKILAGLIKESSGSILLNGKPikakerrkSIGYVMQDv 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 401 --QAEFKSSKTILDYVWDQYPLMNEKdIRAVLGRF-LFVQDDVKKIinDLSGGEKARLQLALLMLQRDNVLILDEPTNHL 477
Cdd:cd03226 81 dyQLFTDSVREELLLGLKELDAGNEQ-AETVLKDLdLYALKERHPL--SLSGGQKQRLAIAAALLSGKDLLIFDEPTSGL 157
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 446524717 478 DIDSKE-----MLEQALQhfEGTILFVSHDRYFINQLANKVfdLTIDGGK 522
Cdd:cd03226 158 DYKNMErvgelIRELAAQ--GKAVIVITHDYEFLAKVCDRV--LLLANGA 203
|
|
| EcfA2 |
COG1122 |
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and ... |
4-257 |
2.64e-18 |
|
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and metabolism, General function prediction only];
Pssm-ID: 440739 [Multi-domain] Cd Length: 230 Bit Score: 84.31 E-value: 2.64e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 4 LQLNHISKSF-DGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNVS------KIKNL-----KLGYL 71
Cdd:COG1122 1 IELENLSFSYpGGTPALDDVSLSIEKGEFVAIIGPNGSGKSTLLRLLNGLLKPTSGEVLvdgkdiTKKNLrelrrKVGLV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 72 TQ----QMTlnsNATVFEEMSkpFehikrmeslikeetdwlskhandydsdtykthmsryeSLSNQfeQLEGYQYESKIK 147
Cdd:COG1122 81 FQnpddQLF---APTVEEDVA--F-------------------------------------GPENL--GLPREEIRERVE 116
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 148 TVL--HGLnfseEDF-NKPINDFSGGQKTRLSLAQ----------MllnepdllllDEPTNHLDLETTKWLEDYLRYFKG 214
Cdd:COG1122 117 EALelVGL----EHLaDRPPHELSGGQKQRVAIAGvlamepevlvL----------DEPTAGLDPRGRRELLELLKRLNK 182
|
250 260 270 280
....*....|....*....|....*....|....*....|....*.
gi 446524717 215 A---IVIISHDRYFLDKIVTQIYDVALGDVkRYVGNYEEFIQQRDL 257
Cdd:COG1122 183 EgktVIIVTHDLDLVAELADRVIVLDDGRI-VADGTPREVFSDYEL 227
|
|
| ABC_RNaseL_inhibitor_domain2 |
cd03237 |
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ... |
351-515 |
3.87e-18 |
|
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity of more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.
Pssm-ID: 213204 [Multi-domain] Cd Length: 246 Bit Score: 84.38 E-value: 3.87e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 351 EVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITFgANLQIGYYDQK-QAEFK-------SSKTILDYVWDQY--PL 420
Cdd:cd03237 21 SISESEVIGILGPNGIGKTTFIKMLAGVLKPDEGDIEI-ELDTVSYKPQYiKADYEgtvrdllSSITKDFYTHPYFktEI 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 421 MNEKDIRAVLGRFLfvqddvkkiiNDLSGGEKARLQLALLMLQRDNVLILDEPTNHLDIDSKEMLEQALQHF----EGTI 496
Cdd:cd03237 100 AKPLQIEQILDREV----------PELSGGELQRVAIAACLSKDADIYLLDEPSAYLDVEQRLMASKVIRRFaennEKTA 169
|
170 180
....*....|....*....|.
gi 446524717 497 LFVSHDRYFINQLANK--VFD 515
Cdd:cd03237 170 FVVEHDIIMIDYLADRliVFE 190
|
|
| ABC_NikE_OppD_transporters |
cd03257 |
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter ... |
330-523 |
5.61e-18 |
|
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter subfamily specific for the transport of dipeptides, oligopeptides (OppD), and nickel (NikDE). The NikABCDE system of E. coli belongs to this family and is composed of the periplasmic binding protein NikA, two integral membrane components (NikB and NikC), and two ATPase (NikD and NikE). The NikABCDE transporter is synthesized under anaerobic conditions to meet the increased demand for nickel resulting from hydrogenase synthesis. The molecular mechanism of nickel uptake in many bacteria and most archaea is not known. Many other members of this ABC family are also involved in the uptake of dipeptides and oligopeptides. The oligopeptide transport system (Opp) is a five-component ABC transport composed of a membrane-anchored substrate binding proteins (SRP), OppA, two transmembrane proteins, OppB and OppC, and two ATP-binding domains, OppD and OppF.
Pssm-ID: 213224 [Multi-domain] Cd Length: 228 Bit Score: 83.32 E-value: 5.61e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 330 VMHVKNLEIGYQT-----AITKPISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITFGANLQIGYYDQKQAEF 404
Cdd:cd03257 1 LLEVKNLSVSFPTgggsvKALDDVSFSIKKGETLGLVGESGSGKSTLARAILGLLKPTSGSIIFDGKDLLKLSRRLRKIR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 405 KS---------------SKTILDYVWD----QYPLMNEKDIRAVLGRFLFVQDDVKKIIN----DLSGGEKARLQLALLM 461
Cdd:cd03257 81 RKeiqmvfqdpmsslnpRMTIGEQIAEplriHGKLSKKEARKEAVLLLLVGVGLPEEVLNryphELSGGQRQRVAIARAL 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446524717 462 LQRDNVLILDEPTNHLDIDSK----EMLEQALQHFEGTILFVSHDRYFINQLANKVfdLTIDGGKM 523
Cdd:cd03257 161 ALNPKLLIADEPTSALDVSVQaqilDLLKKLQEELGLTLLFITHDLGVVAKIADRV--AVMYAGKI 224
|
|
| PRK03695 |
PRK03695 |
vitamin B12-transporter ATPase; Provisional |
331-502 |
7.45e-18 |
|
vitamin B12-transporter ATPase; Provisional
Pssm-ID: 235150 [Multi-domain] Cd Length: 248 Bit Score: 83.44 E-value: 7.45e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 331 MHVKNLEIGYQTAitkPISIEVSKGDHIAIIGPNGIGKSTLIKTIAN----------QQKALNGYITFGANLQIGYYDQK 400
Cdd:PRK03695 1 MQLNDVAVSTRLG---PLSAEVRAGEILHLVGPNGAGKSTLLARMAGllpgsgsiqfAGQPLEAWSAAELARHRAYLSQQ 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 401 QaefkSSKTILDyVWdQY------PLMNEKDIRAVLG---RFLFVQDDVKKIINDLSGGEKARLQLALLMLQRD------ 465
Cdd:PRK03695 78 Q----TPPFAMP-VF-QYltlhqpDKTRTEAVASALNevaEALGLDDKLGRSVNQLSGGEWQRVRLAAVVLQVWpdinpa 151
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 446524717 466 -NVLILDEPTNHLDIDSKEMLEQALQHFE---GTILFVSHD 502
Cdd:PRK03695 152 gQLLLLDEPMNSLDVAQQAALDRLLSELCqqgIAVVMSSHD 192
|
|
| ABC_ATPase |
cd00267 |
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large ... |
5-239 |
1.60e-17 |
|
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213179 [Multi-domain] Cd Length: 157 Bit Score: 79.98 E-value: 1.60e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 5 QLNHISKSFDGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNVskiknlklgyltqqmtlnsnatvf 84
Cdd:cd00267 1 EIENLSFRYGGRTALDNVSLTLKAGEIVALVGPNGSGKSTLLRAIAGLLKPTSGEI------------------------ 56
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 85 eemskpfehikrmeslikeetDWLSKHANDYDSDTYKTHMSryeslsnqfeqlegyqyeskiktVLHGLnfseedfnkpi 164
Cdd:cd00267 57 ---------------------LIDGKDIAKLPLEELRRRIG-----------------------YVPQL----------- 81
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446524717 165 ndfSGGQKTRLSLAQMLLNEPDLLLLDEPTNHLDLETTKWLEDYLRYFKG---AIVIISHDRYFLDKIVTQIYDVALG 239
Cdd:cd00267 82 ---SGGQRQRVALARALLLNPDLLLLDEPTSGLDPASRERLLELLRELAEegrTVIIVTHDPELAELAADRVIVLKDG 156
|
|
| ABC_Metallic_Cations |
cd03235 |
ATP-binding cassette domain of the metal-type transporters; This family includes transporters ... |
5-230 |
1.93e-17 |
|
ATP-binding cassette domain of the metal-type transporters; This family includes transporters involved in the uptake of various metallic cations such as iron, manganese, and zinc. The ATPases of this group of transporters are very similar to members of iron-siderophore uptake family suggesting that they share a common ancestor. The best characterized metal-type ABC transporters are the YfeABCD system of Y. pestis, the SitABCD system of Salmonella enterica serovar Typhimurium, and the SitABCD transporter of Shigella flexneri. Moreover other uncharacterized homologs of these metal-type transporters are mainly found in pathogens like Haemophilus or enteroinvasive E. coli isolates.
Pssm-ID: 213202 [Multi-domain] Cd Length: 213 Bit Score: 81.43 E-value: 1.93e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 5 QLNHISKSFDGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNVS------KIKNLKLGYLTQQMTLN 78
Cdd:cd03235 1 EVEDLTVSYGGHPVLEDVSFEVKPGEFLAIVGPNGAGKSTLLKAILGLLKPTSGSIRvfgkplEKERKRIGYVPQRRSID 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 79 SN--ATVFEEMSKPFEHIKRMESLIKEETDWLSKHAndydsdtykthmsryeslsnqfeqlegyqyeskIKTVlhGLnfs 156
Cdd:cd03235 81 RDfpISVRDVVLMGLYGHKGLFRRLSKADKAKVDEA---------------------------------LERV--GL--- 122
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 157 eEDF-NKPINDFSGGQKTRLSLAQMLLNEPDLLLLDEPTNHLDLETTKWLEDYLRYFKG---AIVIISHD----RYFLDK 228
Cdd:cd03235 123 -SELaDRQIGELSGGQQQRVLLARALVQDPDLLLLDEPFAGVDPKTQEDIYELLRELRRegmTILVVTHDlglvLEYFDR 201
|
..
gi 446524717 229 IV 230
Cdd:cd03235 202 VL 203
|
|
| PRK10247 |
PRK10247 |
putative ABC transporter ATP-binding protein YbbL; Provisional |
325-523 |
2.33e-17 |
|
putative ABC transporter ATP-binding protein YbbL; Provisional
Pssm-ID: 182331 [Multi-domain] Cd Length: 225 Bit Score: 81.68 E-value: 2.33e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 325 NTGNDVMHVKNleIGYQTAITK---PISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITF-GANL-------- 392
Cdd:PRK10247 2 QENSPLLQLQN--VGYLAGDAKilnNISFSLRAGEFKLITGPSGCGKSTLLKIVASLISPTSGTLLFeGEDIstlkpeiy 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 393 --QIGYYDQKQAEFksSKTILDYVWDQYPLMN----EKDIRAVLGRFLFVQDDVKKIINDLSGGEKARLQLA--LLMLQR 464
Cdd:PRK10247 80 rqQVSYCAQTPTLF--GDTVYDNLIFPWQIRNqqpdPAIFLDDLERFALPDTILTKNIAELSGGEKQRISLIrnLQFMPK 157
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446524717 465 dnVLILDEPTNHLDIDSK----EMLEQALQHFEGTILFVSHDRYFINQlANKVFDLTIDGGKM 523
Cdd:PRK10247 158 --VLLLDEITSALDESNKhnvnEIIHRYVREQNIAVLWVTHDKDEINH-ADKVITLQPHAGEM 217
|
|
| PRK13409 |
PRK13409 |
ribosome biogenesis/translation initiation ATPase RLI; |
2-229 |
2.70e-17 |
|
ribosome biogenesis/translation initiation ATPase RLI;
Pssm-ID: 184037 [Multi-domain] Cd Length: 590 Bit Score: 85.63 E-value: 2.70e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 2 ILLQLNHISKSFDGediFT-DVDF-EVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNVSkiKNLKLGYLTQQMTLNS 79
Cdd:PRK13409 339 TLVEYPDLTKKLGD---FSlEVEGgEIYEGEVIGIVGPNGIGKTTFAKLLAGVLKPDEGEVD--PELKISYKPQYIKPDY 413
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 80 NATVFeemskpfehikrmeslikeetDWLSKHANDYDSDTYKTHmsryeslsnqfeqlegyqyeskiktVLHGLNFsEED 159
Cdd:PRK13409 414 DGTVE---------------------DLLRSITDDLGSSYYKSE-------------------------IIKPLQL-ERL 446
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446524717 160 FNKPINDFSGGQKTRLSLAQMLLNEPDLLLLDEPTNHLDLE----TTKWLEDYLRYFKGAIVIISHDRYFLDKI 229
Cdd:PRK13409 447 LDKNVKDLSGGELQRVAIAACLSRDADLYLLDEPSAHLDVEqrlaVAKAIRRIAEEREATALVVDHDIYMIDYI 520
|
|
| ABC_MetN_methionine_transporter |
cd03258 |
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ... |
1-221 |
2.90e-17 |
|
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ABC-type transporter encoded by metN of the metNPQ operon in Bacillus subtilis that is involved in methionine transport. Other members of this system include the MetP permease and the MetQ substrate binding protein. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213225 [Multi-domain] Cd Length: 233 Bit Score: 81.47 E-value: 2.90e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 1 MILLQlnHISKSFDGEDIFT----DVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSG-------NVSKIKNLKL- 68
Cdd:cd03258 1 MIELK--NVSKVFGDTGGKVtalkDVSLSVPKGEIFGIIGRSGAGKSTLIRCINGLERPTSGsvlvdgtDLTLLSGKELr 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 69 ------GYLTQQMTLNSNATVFEEMSKPFEHikrmeslikeetdwlskhandydsdtykTHMSRYESlsnqfeqlegyqy 142
Cdd:cd03258 79 karrriGMIFQHFNLLSSRTVFENVALPLEI----------------------------AGVPKAEI------------- 117
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 143 ESKIKTVLHGLNFSEEDFNKPINdFSGGQKTRLSLAQMLLNEPDLLLLDEPTNHLDLETT----KWLEDYLRYFKGAIVI 218
Cdd:cd03258 118 EERVLELLELVGLEDKADAYPAQ-LSGGQKQRVGIARALANNPKVLLCDEATSALDPETTqsilALLRDINRELGLTIVL 196
|
...
gi 446524717 219 ISH 221
Cdd:cd03258 197 ITH 199
|
|
| ABCC_Protease_Secretion |
cd03246 |
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of ... |
339-516 |
3.73e-17 |
|
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of the protease secretion system PrtD, a 60-kDa integral membrane protein sharing 37% identity with HlyB, the ABC component of the alpha-hemolysin secretion pathway, in the C-terminal domain. They export degradative enzymes by using a type I protein secretion system and lack an N-terminal signal peptide, but contain a C-terminal secretion signal. The Type I secretion apparatus is made up of three components, an ABC transporter, a membrane fusion protein (MFP), and an outer membrane protein (OMP). For the HlyA transporter complex, HlyB (ABC transporter) and HlyD (MFP) reside in the inner membrane of E. coli. The OMP component is TolC, which is thought to interact with the MFP to form a continuous channel across the periplasm from the cytoplasm to the exterior. HlyB belongs to the family of ABC transporters, which are ubiquitous, ATP-dependent transmembrane pumps or channels. The spectrum of transport substrates ranges from inorganic ions, nutrients such as amino acids, sugars, or peptides, hydrophobic drugs, to large polypeptides, such as HlyA.
Pssm-ID: 213213 [Multi-domain] Cd Length: 173 Bit Score: 79.57 E-value: 3.73e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 339 GYQTAITKPISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITF-GANL----------QIGYYDQKQAEFksS 407
Cdd:cd03246 12 GAEPPVLRNVSFSIEPGESLAIIGPSGSGKSTLARLILGLLRPTSGRVRLdGADIsqwdpnelgdHVGYLPQDDELF--S 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 408 KTILDyvwdqyplmnekdiravlgrflfvqddvkkiiNDLSGGEKARLQLALLMLQRDNVLILDEPTNHLDIDSKEMLEQ 487
Cdd:cd03246 90 GSIAE--------------------------------NILSGGQRQRLGLARALYGNPRILVLDEPNSHLDVEGERALNQ 137
|
170 180 190
....*....|....*....|....*....|..
gi 446524717 488 ALQHFE---GTILFVSHDRYFINQlANKVFDL 516
Cdd:cd03246 138 AIAALKaagATRIVIAHRPETLAS-ADRILVL 168
|
|
| TagH |
COG1134 |
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate ... |
21-60 |
4.27e-17 |
|
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440749 [Multi-domain] Cd Length: 245 Bit Score: 81.28 E-value: 4.27e-17
10 20 30 40
....*....|....*....|....*....|....*....|
gi 446524717 21 DVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNV 60
Cdd:COG1134 44 DVSFEVERGESVGIIGRNGAGKSTLLKLIAGILEPTSGRV 83
|
|
| ABC_Carb_Solutes_like |
cd03259 |
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is ... |
331-513 |
4.60e-17 |
|
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is comprised of proteins involved in the transport of apparently unrelated solutes and proteins specific for di- and oligosaccharides and polyols. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213226 [Multi-domain] Cd Length: 213 Bit Score: 80.26 E-value: 4.60e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 331 MHVKNLEIGYQ-TAITKPISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITF-GANLQ--------IGYYDQK 400
Cdd:cd03259 1 LELKGLSKTYGsVRALDDLSLTVEPGEFLALLGPSGCGKTTLLRLIAGLERPDSGEILIdGRDVTgvpperrnIGMVFQD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 401 QAEFkSSKTILDYVwdQYPL----MNEKDIRAVLGRFLF---VQDDVKKIINDLSGGEKARLQLALLMLQRDNVLILDEP 473
Cdd:cd03259 81 YALF-PHLTVAENI--AFGLklrgVPKAEIRARVRELLElvgLEGLLNRYPHELSGGQQQRVALARALAREPSLLLLDEP 157
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 446524717 474 TNHLDIDSKEMLE---QALQHFEG-TILFVSHDRYFINQLANKV 513
Cdd:cd03259 158 LSALDAKLREELReelKELQRELGiTTIYVTHDQEEALALADRI 201
|
|
| ABC_Carb_Monos_I |
cd03216 |
First domain of the ATP-binding cassette component of monosaccharide transport system; This ... |
4-61 |
6.81e-17 |
|
First domain of the ATP-binding cassette component of monosaccharide transport system; This family represents the domain I of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. Pentoses include xylose, arabinose, and ribose. Important hexoses include glucose, galactose, and fructose. In members of the Carb_monos family, the single hydrophobic gene product forms a homodimer while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.
Pssm-ID: 213183 [Multi-domain] Cd Length: 163 Bit Score: 78.24 E-value: 6.81e-17
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 446524717 4 LQLNHISKSFDGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNVS 61
Cdd:cd03216 1 LELRGITKRFGGVKALDGVSLSVRRGEVHALLGENGAGKSTLMKILSGLYKPDSGEIL 58
|
|
| ABC_NrtD_SsuB_transporters |
cd03293 |
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ... |
331-502 |
8.58e-17 |
|
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ATP-binding subunits of the bacterial ABC-type nitrate and sulfonate transport systems, respectively. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213260 [Multi-domain] Cd Length: 220 Bit Score: 79.82 E-value: 8.58e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 331 MHVKNLEIGYQTAITK-----PISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITF------GANLQIGYYDQ 399
Cdd:cd03293 1 LEVRNVSKTYGGGGGAvtaleDISLSVEEGEFVALVGPSGCGKSTLLRIIAGLERPTSGEVLVdgepvtGPGPDRGYVFQ 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 400 KQAEFKsSKTILDYVwdQYPL----MNEKDIRAVLGRFL-FV--QDDVKKIINDLSGGEKARLQLALLMLQRDNVLILDE 472
Cdd:cd03293 81 QDALLP-WLTVLDNV--ALGLelqgVPKAEARERAEELLeLVglSGFENAYPHQLSGGMRQRVALARALAVDPDVLLLDE 157
|
170 180 190
....*....|....*....|....*....|....
gi 446524717 473 PTNHLDIDSKEMLEQAL----QHFEGTILFVSHD 502
Cdd:cd03293 158 PFSALDALTREQLQEELldiwRETGKTVLLVTHD 191
|
|
| ABCC_bacteriocin_exporters |
cd03245 |
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic ... |
341-523 |
9.84e-17 |
|
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic bacteriocins of lactic acid bacteria are produced as precursors which have N-terminal leader peptides that share similarities in amino acid sequence and contain a conserved processing site of two glycine residues in positions -1 and -2. A dedicated ATP-binding cassette (ABC) transporter is responsible for the proteolytic cleavage of the leader peptides and subsequent translocation of the bacteriocins across the cytoplasmic membrane.
Pssm-ID: 213212 [Multi-domain] Cd Length: 220 Bit Score: 79.56 E-value: 9.84e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 341 QTAITKPISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITF-GANLQ----------IGYYDQKQAEFksSKT 409
Cdd:cd03245 16 EIPALDNVSLTIRAGEKVAIIGRVGSGKSTLLKLLAGLYKPTSGSVLLdGTDIRqldpadlrrnIGYVPQDVTLF--YGT 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 410 ILDYVWDQYPLMNEKDIRAVLgRFLFVQDDVKKIIN-----------DLSGGEKARLQLALLMLQRDNVLILDEPTNHLD 478
Cdd:cd03245 94 LRDNITLGAPLADDERILRAA-ELAGVTDFVNKHPNgldlqigergrGLSGGQRQAVALARALLNDPPILLLDEPTSAMD 172
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 446524717 479 IDSKEMLEQALQHFEG--TILFVSHdRYFINQLANKVfdLTIDGGKM 523
Cdd:cd03245 173 MNSEERLKERLRQLLGdkTLIIITH-RPSLLDLVDRI--IVMDSGRI 216
|
|
| ABC_MJ0796_LolCDE_FtsE |
cd03255 |
ATP-binding cassette domain of the transporters involved in export of lipoprotein and ... |
333-522 |
1.05e-16 |
|
ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and Cell division ATP-binding protein FtsE; This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.
Pssm-ID: 213222 [Multi-domain] Cd Length: 218 Bit Score: 79.46 E-value: 1.05e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 333 VKNLEIGYQTAIT-----KPISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITFGANLQIGYYDQKQAEFKSS 407
Cdd:cd03255 3 LKNLSKTYGGGGEkvqalKGVSLSIEKGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVRVDGTDISKLSEKELAAFRRR 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 408 K--------------TILDYVwdQYPLM--------NEKDIRAVLGRfLFVQDDVKKIINDLSGGEKARLQLALLMLQRD 465
Cdd:cd03255 83 HigfvfqsfnllpdlTALENV--ELPLLlagvpkkeRRERAEELLER-VGLGDRLNHYPSELSGGQQQRVAIARALANDP 159
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446524717 466 NVLILDEPTNHLDID-SKEMLE--QALQHFEG-TILFVSHDRyFINQLANKVfdLTIDGGK 522
Cdd:cd03255 160 KIILADEPTGNLDSEtGKEVMEllRELNKEAGtTIVVVTHDP-ELAEYADRI--IELRDGK 217
|
|
| ABC_MJ0796_LolCDE_FtsE |
cd03255 |
ATP-binding cassette domain of the transporters involved in export of lipoprotein and ... |
4-231 |
1.17e-16 |
|
ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and Cell division ATP-binding protein FtsE; This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.
Pssm-ID: 213222 [Multi-domain] Cd Length: 218 Bit Score: 79.07 E-value: 1.17e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 4 LQLNHISKSFDGED----IFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNV---------------SKIK 64
Cdd:cd03255 1 IELKNLSKTYGGGGekvqALKGVSLSIEKGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVrvdgtdisklsekelAAFR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 65 NLKLGYLTQQMTLNSNATVFEEMSKPFEHIKRMESLIKEetdwlskhandydsdtykthmsRYESLsnqFEQLegyqyes 144
Cdd:cd03255 81 RRHIGFVFQSFNLLPDLTALENVELPLLLAGVPKKERRE----------------------RAEEL---LERV------- 128
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 145 kiktvlhGLnfsEEDFNKPINDFSGGQKTRLSLAQMLLNEPDLLLLDEPTNHLDLETTK----WLEDYLRYFKGAIVIIS 220
Cdd:cd03255 129 -------GL---GDRLNHYPSELSGGQQQRVAIARALANDPKIILADEPTGNLDSETGKevmeLLRELNKEAGTTIVVVT 198
|
250
....*....|....
gi 446524717 221 HDRYFL---DKIVT 231
Cdd:cd03255 199 HDPELAeyaDRIIE 212
|
|
| MglA |
COG1129 |
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; |
1-60 |
1.27e-16 |
|
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440745 [Multi-domain] Cd Length: 497 Bit Score: 83.14 E-value: 1.27e-16
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 1 MILLQLNHISKSFDGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNV 60
Cdd:COG1129 2 EPLLEMRGISKSFGGVKALDGVSLELRPGEVHALLGENGAGKSTLMKILSGVYQPDSGEI 61
|
|
| BtuD |
COG4138 |
ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism]; ... |
347-502 |
1.78e-16 |
|
ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism];
Pssm-ID: 443313 [Multi-domain] Cd Length: 248 Bit Score: 79.50 E-value: 1.78e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 347 PISIEVSKGDHIAIIGPNGIGKSTLIKTIAN----------QQKALNGYITFGANLQIGYYDQKQaefkSSKTILDyVWd 416
Cdd:COG4138 14 PISAQVNAGELIHLIGPNGAGKSTLLARMAGllpgqgeillNGRPLSDWSAAELARHRAYLSQQQ----SPPFAMP-VF- 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 417 QY-------PLMNEKDIRAV--LGRFLFVQDDVKKIINDLSGGEKARLQLALLMLQ---RDN----VLILDEPTNHLDID 480
Cdd:COG4138 88 QYlalhqpaGASSEAVEQLLaqLAEALGLEDKLSRPLTQLSGGEWQRVRLAAVLLQvwpTINpegqLLLLDEPMNSLDVA 167
|
170 180
....*....|....*....|....*
gi 446524717 481 SKEMLEQALQHF---EGTILFVSHD 502
Cdd:COG4138 168 QQAALDRLLRELcqqGITVVMSSHD 192
|
|
| fecE |
PRK11231 |
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE; |
331-508 |
1.82e-16 |
|
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;
Pssm-ID: 183044 [Multi-domain] Cd Length: 255 Bit Score: 79.67 E-value: 1.82e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 331 MHVKNLEIGYQ-TAITKPISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITFGANlQIGYYDQKQ-------- 401
Cdd:PRK11231 3 LRTENLTVGYGtKRILNDLSLSLPTGKITALIGPNGCGKSTLLKCFARLLTPQSGTVFLGDK-PISMLSSRQlarrlall 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 402 ------AEFKSSKTILDY-------VWDQyplMNEKDIRAVLGRFLFVQDD--VKKIINDLSGGEKARLQLALLMLQRDN 466
Cdd:PRK11231 82 pqhhltPEGITVRELVAYgrspwlsLWGR---LSAEDNARVNQAMEQTRINhlADRRLTDLSGGQRQRAFLAMVLAQDTP 158
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 446524717 467 VLILDEPTNHLDIDSK-EM--LEQALQHFEGTILFVSHDryfINQ 508
Cdd:PRK11231 159 VVLLDEPTTYLDINHQvELmrLMRELNTQGKTVVTVLHD---LNQ 200
|
|
| ABC_drug_resistance_like |
cd03264 |
ABC-type multidrug transport system, ATPase component; The biological function of this family ... |
4-200 |
1.93e-16 |
|
ABC-type multidrug transport system, ATPase component; The biological function of this family is not well characterized, but display ABC domains similar to members of ABCA subfamily. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213231 [Multi-domain] Cd Length: 211 Bit Score: 78.39 E-value: 1.93e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 4 LQLNHISKSFDGEDIFTDVDFEVKTGeRIGIVGRNGAGKSTLMKIIAGVENYDSGNV-----------SKIKNlKLGYLT 72
Cdd:cd03264 1 LQLENLTKRYGKKRALDGVSLTLGPG-MYGLLGPNGAGKTTLMRILATLTPPSSGTIridgqdvlkqpQKLRR-RIGYLP 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 73 QQMTLNSNATVFEEMskpfEHIKRMeslikeetdwlsKHANDYDSDtykthmsryeslsnqfeqlegyqyeSKIKTVLHG 152
Cdd:cd03264 79 QEFGVYPNFTVREFL----DYIAWL------------KGIPSKEVK-------------------------ARVDEVLEL 117
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 446524717 153 LNFSEEDfNKPINDFSGGQKTRLSLAQMLLNEPDLLLLDEPTNHLDLE 200
Cdd:cd03264 118 VNLGDRA-KKKIGSLSGGMRRRVGIAQALVGDPSILIVDEPTAGLDPE 164
|
|
| SunT |
COG2274 |
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase ... |
4-260 |
2.52e-16 |
|
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms];
Pssm-ID: 441875 [Multi-domain] Cd Length: 711 Bit Score: 82.96 E-value: 2.52e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 4 LQLNHISKSFDGED--IFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNVS----KIKNLKLGYLTQQMTL 77
Cdd:COG2274 474 IELENVSFRYPGDSppVLDNISLTIKPGERVAIVGRSGSGKSTLLKLLLGLYEPTSGRILidgiDLRQIDPASLRRQIGV 553
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 78 NS------NATVFE--EMSKP---FEHIKR--MESLIKEEtdwLSKHANDYDsdtykTHMSryeslsnqfeqlEGyqyes 144
Cdd:COG2274 554 VLqdvflfSGTIREniTLGDPdatDEEIIEaaRLAGLHDF---IEALPMGYD-----TVVG------------EG----- 608
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 145 kiktvlhGLNFSeedfnkpindfsGGQKTRLSLAQ----------MllnepdllllDEPTNHLDLETTKWLEDYL-RYFK 213
Cdd:COG2274 609 -------GSNLS------------GGQRQRLAIARallrnpriliL----------DEATSALDAETEAIILENLrRLLK 659
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*....
gi 446524717 214 GA-IVIISH--------DR-YFLD--KIVTQiydvalgdvkryvGNYEEFIQQRDLYYQ 260
Cdd:COG2274 660 GRtVIIIAHrlstirlaDRiIVLDkgRIVED-------------GTHEELLARKGLYAE 705
|
|
| AztA |
NF040873 |
zinc ABC transporter ATP-binding protein AztA; |
348-502 |
3.48e-16 |
|
zinc ABC transporter ATP-binding protein AztA;
Pssm-ID: 468810 [Multi-domain] Cd Length: 191 Bit Score: 77.27 E-value: 3.48e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 348 ISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITFGANLQIGYYDQKQAEFKS-SKTILDYV----WDQYPLMN 422
Cdd:NF040873 11 VDLTIPAGSLTAVVGPNGSGKSTLLKVLAGVLRPTSGTVRRAGGARVAYVPQRSEVPDSlPLTVRDLVamgrWARRGLWR 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 423 --EKDIRAVLGRFLF---VQDDVKKIINDLSGGEKARLQLALLMLQRDNVLILDEPTNHLDIDSKEMLEQALQ--HFEG- 494
Cdd:NF040873 91 rlTRDDRAAVDDALErvgLADLAGRQLGELSGGQRQRALLAQGLAQEADLLLLDEPTTGLDAESRERIIALLAeeHARGa 170
|
....*...
gi 446524717 495 TILFVSHD 502
Cdd:NF040873 171 TVVVVTHD 178
|
|
| CydC |
COG4987 |
ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease ... |
4-260 |
5.16e-16 |
|
ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444011 [Multi-domain] Cd Length: 569 Bit Score: 81.35 E-value: 5.16e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 4 LQLNHISKSFDGED--IFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNVS----KIKNL-------KLGY 70
Cdd:COG4987 334 LELEDVSFRYPGAGrpVLDGLSLTLPPGERVAIVGPSGSGKSTLLALLLRFLDPQSGSITlggvDLRDLdeddlrrRIAV 413
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 71 LTQQ-----MTL-------NSNATvFEEMskpfehikrMESLIKEE-TDWLSKHANDYDsdtykthmsryeslsnqfeql 137
Cdd:COG4987 414 VPQRphlfdTTLrenlrlaRPDAT-DEEL---------WAALERVGlGDWLAALPDGLD--------------------- 462
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 138 egyqyeskikTVL--HGLNFSeedfnkpindfsGGQKTRLSLAQMLLNEPDLLLLDEPTNHLDLET-TKWLEDYLRYFKG 214
Cdd:COG4987 463 ----------TWLgeGGRRLS------------GGERRRLALARALLRDAPILLLDEPTEGLDAATeQALLADLLEALAG 520
|
250 260 270 280
....*....|....*....|....*....|....*....|....*..
gi 446524717 215 -AIVIISHDRYFLDKiVTQIYDVALGDVKRyVGNYEEFIQQRDLYYQ 260
Cdd:COG4987 521 rTVLLITHRLAGLER-MDRILVLEDGRIVE-QGTHEELLAQNGRYRQ 565
|
|
| ABC_Iron-Siderophores_B12_Hemin |
cd03214 |
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related ... |
5-230 |
6.11e-16 |
|
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; ABC transporters, involved in the uptake of siderophores, heme, and vitamin B12, are widely conserved in bacteria and archaea. Only very few species lack representatives of the siderophore family transporters. The E. coli BtuCD protein is an ABC transporter mediating vitamin B12 uptake. The two ATP-binding cassettes (BtuD) are in close contact with each other, as are the two membrane-spanning subunits (BtuC); this arrangement is distinct from that observed for the E. coli lipid flippase MsbA. The BtuC subunits provide 20 transmembrane helices grouped around a translocation pathway that is closed to the cytoplasm by a gate region, whereas the dimer arrangement of the BtuD subunits resembles the ATP-bound form of the Rad50 DNA repair enzyme. A prominent cytoplasmic loop of BtuC forms the contact region with the ATP-binding cassette and represent a conserved motif among the ABC transporters.
Pssm-ID: 213181 [Multi-domain] Cd Length: 180 Bit Score: 76.32 E-value: 6.11e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 5 QLNHISKSFDGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNVS----KIKNLK-------LGYLTQ 73
Cdd:cd03214 1 EVENLSVGYGGRTVLDDLSLSIEAGEIVGILGPNGAGKSTLLKTLAGLLKPSSGEILldgkDLASLSpkelarkIAYVPQ 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 74 QMtlnsnatvfeemskpfehikrmeslikEETDwlskhandydsdtykthmsryeslsnqfeqlegyqyeskiktVLHgl 153
Cdd:cd03214 81 AL---------------------------ELLG------------------------------------------LAH-- 89
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 154 nFSEedfnKPINDFSGGQKTRLSLAQMLLNEPDLLLLDEPTNHLDL----ETTKWLEDYLRYFKGAIVIISHD-----RY 224
Cdd:cd03214 90 -LAD----RPFNELSGGERQRVLLARALAQEPPILLLDEPTSHLDIahqiELLELLRRLARERGKTVVMVLHDlnlaaRY 164
|
....*.
gi 446524717 225 FlDKIV 230
Cdd:cd03214 165 A-DRVI 169
|
|
| CydD |
TIGR02857 |
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family ... |
333-516 |
7.12e-16 |
|
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex. Unfortunately, the gene symbol nomenclature adopted based on this operon in B. subtilis assigns cydC to the third gene in the operon where this gene is actually homologous to the E. coli cydD gene. We have chosen to name all homologs in this family in accordance with the precedence of publication of the E. coli name, CydD
Pssm-ID: 274323 [Multi-domain] Cd Length: 529 Bit Score: 80.79 E-value: 7.12e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 333 VKNLEIGY--QTAITKPISIEVSKGDHIAIIGPNGIGKSTLIKTIANQ------QKALNGYITFGANL-----QIGYYDQ 399
Cdd:TIGR02857 324 FSGVSVAYpgRRPALRPVSFTVPPGERVALVGPSGAGKSTLLNLLLGFvdptegSIAVNGVPLADADAdswrdQIAWVPQ 403
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 400 KQAEFksSKTILDYVWDQYPLMNEKDIRAVL---GRFLFVQD---DVKKIIND----LSGGEKARLQLALLMLQRDNVLI 469
Cdd:TIGR02857 404 HPFLF--AGTIAENIRLARPDASDAEIREALeraGLDEFVAAlpqGLDTPIGEggagLSGGQAQRLALARAFLRDAPLLL 481
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 446524717 470 LDEPTNHLDIDS-KEMLEQALQHFEG-TILFVSHDRYFInQLANKVFDL 516
Cdd:TIGR02857 482 LDEPTAHLDAETeAEVLEALRALAQGrTVLLVTHRLALA-ALADRIVVL 529
|
|
| ABC_PhnC_transporter |
cd03256 |
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; ... |
4-230 |
8.58e-16 |
|
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Phosphonates are a class of organophosphorus compounds characterized by a chemically stable carbon-to-phosphorus (C-P) bond. Phosphonates are widespread among naturally occurring compounds in all kingdoms of wildlife, but only prokaryotic microorganisms are able to cleave this bond. Certain bacteria such as E. coli can use alkylphosphonates as a phosphorus source. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213223 [Multi-domain] Cd Length: 241 Bit Score: 77.22 E-value: 8.58e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 4 LQLNHISKSF-DGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNVS----KIKNLKLGYLTQ---QM 75
Cdd:cd03256 1 IEVENLSKTYpNGKKALKDVSLSINPGEFVALIGPSGAGKSTLLRCLNGLVEPTSGSVLidgtDINKLKGKALRQlrrQI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 76 tlnsnATVFEEmskpFEHIKRMESLikeeTDWLSKHANdydsdtyktHMSRYESLSNQFEQLEGYQYESKIKTVlhGLnf 155
Cdd:cd03256 81 -----GMIFQQ----FNLIERLSVL----ENVLSGRLG---------RRSTWRSLFGLFPKEEKQRALAALERV--GL-- 134
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 156 sEEDFNKPINDFSGGQKTRLSLAQMLLNEPDLLLLDEPTNHLDLETTKWLEDYLRYF---KGAIVIIS-HD----RYFLD 227
Cdd:cd03256 135 -LDKAYQRADQLSGGQQQRVAIARALMQQPKLILADEPVASLDPASSRQVMDLLKRInreEGITVIVSlHQvdlaREYAD 213
|
...
gi 446524717 228 KIV 230
Cdd:cd03256 214 RIV 216
|
|
| PRK15439 |
PRK15439 |
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional |
3-513 |
1.02e-15 |
|
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
Pssm-ID: 185336 [Multi-domain] Cd Length: 510 Bit Score: 80.48 E-value: 1.02e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 3 LLQLNHISKSFDGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSG----------NVSKIKNLKLG-YL 71
Cdd:PRK15439 11 LLCARSISKQYSGVEVLKGIDFTLHAGEVHALLGGNGAGKSTLMKIIAGIVPPDSGtleiggnpcaRLTPAKAHQLGiYL 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 72 T-QQMTLNSNATVFEE----MSKPFEHIKRMESLIKEETDWLSKHANDYDSDTYKTHMsryeslsnqFEQLEGYQYESKI 146
Cdd:PRK15439 91 VpQEPLLFPNLSVKENilfgLPKRQASMQKMKQLLAALGCQLDLDSSAGSLEVADRQI---------VEILRGLMRDSRI 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 147 ktvlhglnfseedfnkpindfsggqktrLSLaqmllnepdllllDEPTNHLDLETTKWLEDYLRYF--KG-AIVIISHDR 223
Cdd:PRK15439 162 ----------------------------LIL-------------DEPTASLTPAETERLFSRIRELlaQGvGIVFISHKL 200
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 224 YFLDKIVTQI------YDVALGDVKRYvgNYEEFIQQrdlyyqkrmqeyesqqaeikrletfveknITRASTS-GMAKSR 296
Cdd:PRK15439 201 PEIRQLADRIsvmrdgTIALSGKTADL--STDDIIQA-----------------------------ITPAAREkSLSASQ 249
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 297 RKILE-----KMERIDKPMLDAksaniqfgfDRNTGNDVMHvknleigyqtaitkpISIEVSKGDHIAIIGPNGIGKSTL 371
Cdd:PRK15439 250 KLWLElpgnrRQQAAGAPVLTV---------EDLTGEGFRN---------------ISLEVRAGEILGLAGVVGAGRTEL 305
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 372 IKTIANQQKALNGYITFGaNLQIGYYDQKQA----------EFKSSKTILD--YVWDQYPLM--------NEKDIRAVLG 431
Cdd:PRK15439 306 AETLYGLRPARGGRIMLN-GKEINALSTAQRlarglvylpeDRQSSGLYLDapLAWNVCALThnrrgfwiKPARENAVLE 384
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 432 RF---LFVQ-DDVKKIINDLSGGEKARLQLALLMLQRDNVLILDEPTNHLDIDSKEMLEQALQHFEG---TILFVSHDRY 504
Cdd:PRK15439 385 RYrraLNIKfNHAEQAARTLSGGNQQKVLIAKCLEASPQLLIVDEPTRGVDVSARNDIYQLIRSIAAqnvAVLFISSDLE 464
|
....*....
gi 446524717 505 FINQLANKV 513
Cdd:PRK15439 465 EIEQMADRV 473
|
|
| ABC_Carb_Solutes_like |
cd03259 |
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is ... |
4-223 |
1.21e-15 |
|
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is comprised of proteins involved in the transport of apparently unrelated solutes and proteins specific for di- and oligosaccharides and polyols. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213226 [Multi-domain] Cd Length: 213 Bit Score: 76.02 E-value: 1.21e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 4 LQLNHISKSFDGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNVS----KIKNL-----KLGYLTQQ 74
Cdd:cd03259 1 LELKGLSKTYGSVRALDDLSLTVEPGEFLALLGPSGCGKTTLLRLIAGLERPDSGEILidgrDVTGVpperrNIGMVFQD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 75 MTLNSNATVFEEMSKPFEHIKRMESLIKEETDWLSKHandydsdtykTHMSRYEslsnqfeqlegyqyeskiktvlhgln 154
Cdd:cd03259 81 YALFPHLTVAENIAFGLKLRGVPKAEIRARVRELLEL----------VGLEGLL-------------------------- 124
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446524717 155 fseedfNKPINDFSGGQKTRLSLAQMLLNEPDLLLLDEPTNHLDLETTKWLEDYLR-YFK--GAIVI-ISHDR 223
Cdd:cd03259 125 ------NRYPHELSGGQQQRVALARALAREPSLLLLDEPLSALDAKLREELREELKeLQRelGITTIyVTHDQ 191
|
|
| ABC_ModC_like |
cd03299 |
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely ... |
333-513 |
1.33e-15 |
|
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely related to ModC. ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213266 [Multi-domain] Cd Length: 235 Bit Score: 76.61 E-value: 1.33e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 333 VKNLEIGYQTAITKPISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITF-GANL--------QIGYYDQKQAE 403
Cdd:cd03299 3 VENLSKDWKEFKLKNVSLEVERGDYFVILGPTGSGKSVLLETIAGFIKPDSGKILLnGKDItnlppekrDISYVPQNYAL 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 404 F--KSSKTILDYVWDQYPLMNEKDIRAVL--GRFLFVQDDVKKIINDLSGGEKARLQLALLMLQRDNVLILDEPTNHLDI 479
Cdd:cd03299 83 FphMTVYKNIAYGLKKRKVDKKEIERKVLeiAEMLGIDHLLNRKPETLSGGEQQRVAIARALVVNPKILLLDEPFSALDV 162
|
170 180 190
....*....|....*....|....*....|....*...
gi 446524717 480 DSKE----MLEQALQHFEGTILFVSHDRYFINQLANKV 513
Cdd:cd03299 163 RTKEklreELKKIRKEFGVTVLHVTHDFEEAWALADKV 200
|
|
| CysA |
COG1118 |
ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and ... |
4-223 |
1.49e-15 |
|
ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440735 [Multi-domain] Cd Length: 348 Bit Score: 78.26 E-value: 1.49e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 4 LQLNHISKSFDGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNVS----------KIKNLKLGYLTQ 73
Cdd:COG1118 3 IEVRNISKRFGSFTLLDDVSLEIASGELVALLGPSGSGKTTLLRIIAGLETPDSGRIVlngrdlftnlPPRERRVGFVFQ 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 74 QMTLNSNATVFE------EMSKPFEH-IK-RMESLIKE-ETDWLSKhandydsdtykthmsRYESlsnqfeQLegyqyes 144
Cdd:COG1118 83 HYALFPHMTVAEniafglRVRPPSKAeIRaRVEELLELvQLEGLAD---------------RYPS------QL------- 134
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 145 kiktvlhglnfseedfnkpindfSGGQKTRLSLAQMllnepdllllDEPTNHLD------LEttKWLEDYLRYFKGAIVI 218
Cdd:COG1118 135 -----------------------SGGQRQRVALARAlavepevlllDEPFGALDakvrkeLR--RWLRRLHDELGGTTVF 189
|
....*
gi 446524717 219 ISHDR 223
Cdd:COG1118 190 VTHDQ 194
|
|
| ABC_Org_Solvent_Resistant |
cd03261 |
ATP-binding cassette transport system involved in resistance to organic solvents; ABC ... |
333-502 |
1.67e-15 |
|
ATP-binding cassette transport system involved in resistance to organic solvents; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213228 [Multi-domain] Cd Length: 235 Bit Score: 76.39 E-value: 1.67e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 333 VKNLEIGYQT-AITKPISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYIT-FGANL-------------QIGYY 397
Cdd:cd03261 3 LRGLTKSFGGrTVLKGVDLDVRRGEILAIIGPSGSGKSTLLRLIVGLLRPDSGEVLiDGEDIsglseaelyrlrrRMGML 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 398 DQKQAEFkSSKTILDYVwdQYPL-----MNEKDIRA-VLGRFLFV--QDDVKKIINDLSGGEKARLQLA-LLMLQRDnVL 468
Cdd:cd03261 83 FQSGALF-DSLTVFENV--AFPLrehtrLSEEEIREiVLEKLEAVglRGAEDLYPAELSGGMKKRVALArALALDPE-LL 158
|
170 180 190
....*....|....*....|....*....|....*...
gi 446524717 469 ILDEPTNHLD-IDSKEMLE--QALQ-HFEGTILFVSHD 502
Cdd:cd03261 159 LYDEPTAGLDpIASGVIDDliRSLKkELGLTSIMVTHD 196
|
|
| ABC_Class3 |
cd03229 |
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is ... |
4-230 |
1.98e-15 |
|
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is comprised of all BPD (Binding Protein Dependent) systems that are largely represented in archaea and eubacteria and are primarily involved in scavenging solutes from the environment. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213196 [Multi-domain] Cd Length: 178 Bit Score: 74.53 E-value: 1.98e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 4 LQLNHISKSFDGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNVS-------------KIKNLKLGY 70
Cdd:cd03229 1 LELKNVSKRYGQKTVLNDVSLNIEAGEIVALLGPSGSGKSTLLRCIAGLEEPDSGSILidgedltdledelPPLRRRIGM 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 71 LTQQMTLNSNATVFEemskpfehikrmeslikeetdwlskhandydsdtykthmsryeslsnqfeqlegyqyeskikTVL 150
Cdd:cd03229 81 VFQDFALFPHLTVLE--------------------------------------------------------------NIA 98
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 151 HGLnfseedfnkpindfSGGQKTRLSLAQMLLNEPDLLLLDEPTNHLDLETTKWLEDYLR----YFKGAIVIISHD---- 222
Cdd:cd03229 99 LGL--------------SGGQQQRVALARALAMDPDVLLLDEPTSALDPITRREVRALLKslqaQLGITVVLVTHDldea 164
|
....*...
gi 446524717 223 RYFLDKIV 230
Cdd:cd03229 165 ARLADRVV 172
|
|
| ABC_FeS_Assembly |
cd03217 |
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of ... |
344-514 |
2.71e-15 |
|
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of iron-sulfur clusters (Fe-S) depends on multi-protein systems. The SUF system of E. coli and Erwinia chrysanthemi is important for Fe-S biogenesis under stressful conditions. The SUF system is made of six proteins: SufC is an atypical cytoplasmic ABC-ATPase, which forms a complex with SufB and SufD; SufA plays the role of a scaffold protein for assembly of iron-sulfur clusters and delivery to target proteins; SufS is a cysteine desulfurase which mobilizes the sulfur atom from cysteine and provides it to the cluster; SufE has no associated function yet.
Pssm-ID: 213184 [Multi-domain] Cd Length: 200 Bit Score: 74.87 E-value: 2.71e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 344 ITKPISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQ--KALNGYITFGAnlqigyydqkqaefkssKTILDYvwdqypLM 421
Cdd:cd03217 15 ILKGVNLTIKKGEVHALMGPNGSGKSTLAKTIMGHPkyEVTEGEILFKG-----------------EDITDL------PP 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 422 NEkdiRAVLGRFLFVQDDVK----KIINDL-------SGGEKARLQLALLMLQRDNVLILDEPTNHLDIDSKEMLEQALQ 490
Cdd:cd03217 72 EE---RARLGIFLAFQYPPEipgvKNADFLryvnegfSGGEKKRNEILQLLLLEPDLAILDEPDSGLDIDALRLVAEVIN 148
|
170 180
....*....|....*....|....*...
gi 446524717 491 HF--EGT-ILFVSHDRYFINQL-ANKVF 514
Cdd:cd03217 149 KLreEGKsVLIITHYQRLLDYIkPDRVH 176
|
|
| ABC_Org_Solvent_Resistant |
cd03261 |
ATP-binding cassette transport system involved in resistance to organic solvents; ABC ... |
4-234 |
3.84e-15 |
|
ATP-binding cassette transport system involved in resistance to organic solvents; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213228 [Multi-domain] Cd Length: 235 Bit Score: 75.23 E-value: 3.84e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 4 LQLNHISKSFDGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNV----------SKIKNLKL----G 69
Cdd:cd03261 1 IELRGLTKSFGGRTVLKGVDLDVRRGEILAIIGPSGSGKSTLLRLIVGLLRPDSGEVlidgedisglSEAELYRLrrrmG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 70 YLTQQMTLNSNATVFEEMSKP-FEHIKRMESLIKEetdwlskhandydsdtykthmsryeslsnqfeqlegyQYESKIKT 148
Cdd:cd03261 81 MLFQSGALFDSLTVFENVAFPlREHTRLSEEEIRE-------------------------------------IVLEKLEA 123
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 149 VlhGLnfsEEDFNKPINDFSGGQKTRLSLAQMLLNEPDLLLLDEPTNHLDLETTKWLEDYLRYFKGA----IVIISHDRY 224
Cdd:cd03261 124 V--GL---RGAEDLYPAELSGGMKKRVALARALALDPELLLYDEPTAGLDPIASGVIDDLIRSLKKElgltSIMVTHDLD 198
|
250
....*....|
gi 446524717 225 FLDKIVTQIY 234
Cdd:cd03261 199 TAFAIADRIA 208
|
|
| ABC_KpsT_Wzt |
cd03220 |
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC ... |
18-61 |
4.67e-15 |
|
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC transporter subfamily is involved in extracellular polysaccharide export. Among the variety of membrane-linked or extracellular polysaccharides excreted by bacteria, only capsular polysaccharides, lipopolysaccharides, and teichoic acids have been shown to be exported by ABC transporters. A typical system is made of a conserved integral membrane and an ABC. In addition to these proteins, capsular polysaccharide exporter systems require two 'accessory' proteins to perform their function: a periplasmic (E.coli) or a lipid-anchored outer membrane protein called OMA (Neisseria meningitidis and Haemophilus influenza) and a cytoplasmic membrane protein MPA2.
Pssm-ID: 213187 [Multi-domain] Cd Length: 224 Bit Score: 74.88 E-value: 4.67e-15
10 20 30 40
....*....|....*....|....*....|....*....|....
gi 446524717 18 IFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNVS 61
Cdd:cd03220 37 ALKDVSFEVPRGERIGLIGRNGAGKSTLLRLLAGIYPPDSGTVT 80
|
|
| PRK13409 |
PRK13409 |
ribosome biogenesis/translation initiation ATPase RLI; |
351-515 |
5.95e-15 |
|
ribosome biogenesis/translation initiation ATPase RLI;
Pssm-ID: 184037 [Multi-domain] Cd Length: 590 Bit Score: 78.31 E-value: 5.95e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 351 EVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITFgaNLQIGYYDQkqaefkssktildYVWDQYPLMNEKDIRAVL 430
Cdd:PRK13409 361 EIYEGEVIGIVGPNGIGKTTFAKLLAGVLKPDEGEVDP--ELKISYKPQ-------------YIKPDYDGTVEDLLRSIT 425
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 431 GRFL--FVQDDV----------KKIINDLSGGEKARLQLALLMLQRDNVLILDEPTNHLDIDSKEMLEQALQHF----EG 494
Cdd:PRK13409 426 DDLGssYYKSEIikplqlerllDKNVKDLSGGELQRVAIAACLSRDADLYLLDEPSAHLDVEQRLAVAKAIRRIaeerEA 505
|
170 180
....*....|....*....|...
gi 446524717 495 TILFVSHDRYFINQLANK--VFD 515
Cdd:PRK13409 506 TALVVDHDIYMIDYISDRlmVFE 528
|
|
| PRK10851 |
PRK10851 |
sulfate/thiosulfate ABC transporter ATP-binding protein CysA; |
4-223 |
7.53e-15 |
|
sulfate/thiosulfate ABC transporter ATP-binding protein CysA;
Pssm-ID: 182778 [Multi-domain] Cd Length: 353 Bit Score: 76.28 E-value: 7.53e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 4 LQLNHISKSFDGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSG-------NVSKI--KNLKLGYLTQQ 74
Cdd:PRK10851 3 IEIANIKKSFGRTQVLNDISLDIPSGQMVALLGPSGSGKTTLLRIIAGLEHQTSGhirfhgtDVSRLhaRDRKVGFVFQH 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 75 MTLNSNATVFEEMSKPFEHIKRMESlikeetdwLSKHANDYDSdTYKTHMSRYESLSNQF-EQLegyqyeskiktvlhgl 153
Cdd:PRK10851 83 YALFRHMTVFDNIAFGLTVLPRRER--------PNAAAIKAKV-TQLLEMVQLAHLADRYpAQL---------------- 137
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446524717 154 nfseedfnkpindfSGGQKTRLSLAQMLLNEPDLLLLDEPTNHLDLETTKWLEDYLRY----FKGAIVIISHDR 223
Cdd:PRK10851 138 --------------SGGQKQRVALARALAVEPQILLLDEPFGALDAQVRKELRRWLRQlheeLKFTSVFVTHDQ 197
|
|
| PRK13539 |
PRK13539 |
cytochrome c biogenesis protein CcmA; Provisional |
348-501 |
7.74e-15 |
|
cytochrome c biogenesis protein CcmA; Provisional
Pssm-ID: 237421 [Multi-domain] Cd Length: 207 Bit Score: 73.75 E-value: 7.74e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 348 ISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITF--------GANLQIGYYDQKQAeFKSSKTILDYV--WDQ 417
Cdd:PRK13539 21 LSFTLAAGEALVLTGPNGSGKTTLLRLIAGLLPPAAGTIKLdggdiddpDVAEACHYLGHRNA-MKPALTVAENLefWAA 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 418 YPLMNEKDIRAVLGRFlfvqdDVKKIIN----DLSGGEKARLQLALLMLQRDNVLILDEPTNHLDIDSKEMLEQALQ-HF 492
Cdd:PRK13539 100 FLGGEELDIAAALEAV-----GLAPLAHlpfgYLSAGQKRRVALARLLVSNRPIWILDEPTAALDAAAVALFAELIRaHL 174
|
170
....*....|.
gi 446524717 493 E--GTILFVSH 501
Cdd:PRK13539 175 AqgGIVIAATH 185
|
|
| GsiA |
COG1123 |
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ... |
3-230 |
8.41e-15 |
|
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440740 [Multi-domain] Cd Length: 514 Bit Score: 77.25 E-value: 8.41e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 3 LLQLNHISKSFD--GEDIFT---DVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSG-------NVSKIKNLKLGY 70
Cdd:COG1123 260 LLEVRNLSKRYPvrGKGGVRavdDVSLTLRRGETLGLVGESGSGKSTLARLLLGLLRPTSGsilfdgkDLTKLSRRSLRE 339
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 71 LTQQM---------TLNSNATVFEEMSKPFEHIKRM-ESLIKEETDWLskhandydsdtykthmsryeslsnqfeqLEgy 140
Cdd:COG1123 340 LRRRVqmvfqdpysSLNPRMTVGDIIAEPLRLHGLLsRAERRERVAEL----------------------------LE-- 389
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 141 qyeskiktvLHGLnfSEEDFNKPINDFSGGQKTRLSLAQMllnepdllllDEPTNHLD-------LETtkwLEDYLRYFK 213
Cdd:COG1123 390 ---------RVGL--PPDLADRYPHELSGGQRQRVAIARAlalepkllilDEPTSALDvsvqaqiLNL---LRDLQRELG 455
|
250 260
....*....|....*....|.
gi 446524717 214 GAIVIISHD----RYFLDKIV 230
Cdd:COG1123 456 LTYLFISHDlavvRYIADRVA 476
|
|
| MK0520 |
COG2401 |
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction ... |
341-509 |
1.03e-14 |
|
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction only];
Pssm-ID: 441957 [Multi-domain] Cd Length: 222 Bit Score: 73.84 E-value: 1.03e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 341 QTAITKPISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITFganlqigyyDQKQAEFKSSKTILDYVwdqYPL 420
Cdd:COG2401 42 ERYVLRDLNLEIEPGEIVLIVGASGSGKSTLLRLLAGALKGTPVAGCV---------DVPDNQFGREASLIDAI---GRK 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 421 MNEKDIRAVLGR------FLFvqddvKKIINDLSGGEKARLQLALLMLQRDNVLILDEPTNHLDID-SKEM---LEQALQ 490
Cdd:COG2401 110 GDFKDAVELLNAvglsdaVLW-----LRRFKELSTGQKFRFRLALLLAERPKLLVIDEFCSHLDRQtAKRVarnLQKLAR 184
|
170
....*....|....*....
gi 446524717 491 HFEGTILFVSHDRYFINQL 509
Cdd:COG2401 185 RAGITLVVATHHYDVIDDL 203
|
|
| DppF |
COG1124 |
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ... |
333-547 |
1.05e-14 |
|
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];
Pssm-ID: 440741 [Multi-domain] Cd Length: 248 Bit Score: 74.07 E-value: 1.05e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 333 VKNLEIGYQTA-----ITKPISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITFGANlqigyyDQKQAEFKSS 407
Cdd:COG1124 4 VRNLSVSYGQGgrrvpVLKDVSLEVAPGESFGLVGESGSGKSTLLRALAGLERPWSGEVTFDGR------PVTRRRRKAF 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 408 KTILDYVWdQYP-------------------LMNEKDIRAVLGRFLfvqDDV-------KKIINDLSGGEKARLQLALLM 461
Cdd:COG1124 78 RRRVQMVF-QDPyaslhprhtvdrilaeplrIHGLPDREERIAELL---EQVglppsflDRYPHQLSGGQRQRVAIARAL 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 462 LQRDNVLILDEPTNHLD-IDSKEMLE--QALQHFEG-TILFVSHDRYFINQLANKVFDLtiDGGKMylgdyqyyIEKVEE 537
Cdd:COG1124 154 ILEPELLLLDEPTSALDvSVQAEILNllKDLREERGlTYLFVSHDLAVVAHLCDRVAVM--QNGRI--------VEELTV 223
|
250
....*....|
gi 446524717 538 AEALKAHQEE 547
Cdd:COG1124 224 ADLLAGPKHP 233
|
|
| Rli1 |
COG1245 |
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ... |
2-229 |
1.23e-14 |
|
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];
Pssm-ID: 440858 [Multi-domain] Cd Length: 592 Bit Score: 77.13 E-value: 1.23e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 2 ILLQLNHISKSFDGediFT-DVDF-EVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNVSkiKNLKLGYLTQQMTLNS 79
Cdd:COG1245 340 TLVEYPDLTKSYGG---FSlEVEGgEIREGEVLGIVGPNGIGKTTFAKILAGVLKPDEGEVD--EDLKISYKPQYISPDY 414
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 80 NATVfeemskpfehikrmESLIKeetdwlSKHANDYDSDTYKTHmsryeslsnqfeqlegyqyeskiktVLHGLNFsEED 159
Cdd:COG1245 415 DGTV--------------EEFLR------SANTDDFGSSYYKTE-------------------------IIKPLGL-EKL 448
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446524717 160 FNKPINDFSGGQKTRLSLAQMLLNEPDLLLLDEPTNHLDLE----TTKWLEDYLRYFKGAIVIISHDRYFLDKI 229
Cdd:COG1245 449 LDKNVKDLSGGELQRVAIAACLSRDADLYLLDEPSAHLDVEqrlaVAKAIRRFAENRGKTAMVVDHDIYLIDYI 522
|
|
| ABC_TM1139_LivF_branched |
cd03224 |
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of ... |
333-474 |
1.25e-14 |
|
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of the LIV-I bacterial ABC-type two-component transport system that imports neutral, branched-chain amino acids. The E. coli branched-chain amino acid transporter comprises a heterodimer of ABC transporters (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules.
Pssm-ID: 213191 [Multi-domain] Cd Length: 222 Bit Score: 73.24 E-value: 1.25e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 333 VKNLEIGY-QTAITKPISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITFGA--------------------- 390
Cdd:cd03224 3 VENLNAGYgKSQILFGVSLTVPEGEIVALLGRNGAGKTTLLKTIMGLLPPRSGSIRFDGrditglppheraragigyvpe 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 391 ------------NLQIGYYDQKQAEFkssKTILDYVWDQYPLMneKDIRAVLGRflfvqddvkkiinDLSGGEKARLQLA 458
Cdd:cd03224 83 grrifpeltveeNLLLGAYARRRAKR---KARLERVYELFPRL--KERRKQLAG-------------TLSGGEQQMLAIA 144
|
170
....*....|....*.
gi 446524717 459 LLMLQRDNVLILDEPT 474
Cdd:cd03224 145 RALMSRPKLLLLDEPS 160
|
|
| Rli1 |
COG1245 |
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ... |
351-515 |
1.31e-14 |
|
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];
Pssm-ID: 440858 [Multi-domain] Cd Length: 592 Bit Score: 77.13 E-value: 1.31e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 351 EVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITFgaNLQIGYYDQkqaefkssktildYVWDQYPLMNEKDIRAVL 430
Cdd:COG1245 362 EIREGEVLGIVGPNGIGKTTFAKILAGVLKPDEGEVDE--DLKISYKPQ-------------YISPDYDGTVEEFLRSAN 426
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 431 GRFL---FVQDDV----------KKIINDLSGGEKARLQLALLMLQRDNVLILDEPTNHLDIDSKEMLEQALQHF----E 493
Cdd:COG1245 427 TDDFgssYYKTEIikplglekllDKNVKDLSGGELQRVAIAACLSRDADLYLLDEPSAHLDVEQRLAVAKAIRRFaenrG 506
|
170 180
....*....|....*....|....
gi 446524717 494 GTILFVSHDRYFINQLANK--VFD 515
Cdd:COG1245 507 KTAMVVDHDIYLIDYISDRlmVFE 530
|
|
| ABC_Carb_Monos_I |
cd03216 |
First domain of the ATP-binding cassette component of monosaccharide transport system; This ... |
346-501 |
1.64e-14 |
|
First domain of the ATP-binding cassette component of monosaccharide transport system; This family represents the domain I of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. Pentoses include xylose, arabinose, and ribose. Important hexoses include glucose, galactose, and fructose. In members of the Carb_monos family, the single hydrophobic gene product forms a homodimer while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.
Pssm-ID: 213183 [Multi-domain] Cd Length: 163 Bit Score: 71.69 E-value: 1.64e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 346 KPISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITFganlqigyyDQKQAEFKSSKTildyvwdqyplMNEKD 425
Cdd:cd03216 17 DGVSLSVRRGEVHALLGENGAGKSTLMKILSGLYKPDSGEILV---------DGKEVSFASPRD-----------ARRAG 76
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446524717 426 IRAVLgrflfvQddvkkiindLSGGEKARLQLALLMLQRDNVLILDEPTNHLDIDSKEMLEQALQHF--EG-TILFVSH 501
Cdd:cd03216 77 IAMVY------Q---------LSVGERQMVEIARALARNARLLILDEPTAALTPAEVERLFKVIRRLraQGvAVIFISH 140
|
|
| ABC_NatA_like |
cd03267 |
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; ... |
346-526 |
3.01e-14 |
|
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled to proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of the single ATP-binding protein and the single integral membrane protein.
Pssm-ID: 213234 [Multi-domain] Cd Length: 236 Bit Score: 72.75 E-value: 3.01e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 346 KPISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITFGANLQigyYDQKQaEFKS-------SKTILdyVWD-- 416
Cdd:cd03267 38 KGISFTIEKGEIVGFIGPNGAGKTTTLKILSGLLQPTSGEVRVAGLVP---WKRRK-KFLRrigvvfgQKTQL--WWDlp 111
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 417 ---QYPLMNE---------KDIRAVLGRFLFVQDDVKKIINDLSGGEKARLQLALLMLQRDNVLILDEPTNHLDIDSKEM 484
Cdd:cd03267 112 vidSFYLLAAiydlpparfKKRLDELSELLDLEELLDTPVRQLSLGQRMRAEIAAALLHEPEILFLDEPTIGLDVVAQEN 191
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 446524717 485 LEQALQHF----EGTILFVSHDRYFINQLANKVfdLTIDGG-KMYLG 526
Cdd:cd03267 192 IRNFLKEYnrerGTTVLLTSHYMKDIEALARRV--LVIDKGrLLYDG 236
|
|
| YddA |
COG4178 |
ABC-type uncharacterized transport system, permease and ATPase components [General function ... |
328-521 |
3.09e-14 |
|
ABC-type uncharacterized transport system, permease and ATPase components [General function prediction only];
Pssm-ID: 443337 [Multi-domain] Cd Length: 571 Bit Score: 76.00 E-value: 3.09e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 328 NDVMHVKNLEI---GYQTaITKPISIEVSKGDHIAIIGPNGIGKSTLIKTIAnqqkalnGYITFGANlQIGYYDQKQAEF 404
Cdd:COG4178 360 DGALALEDLTLrtpDGRP-LLEDLSLSLKPGERLLITGPSGSGKSTLLRAIA-------GLWPYGSG-RIARPAGARVLF 430
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 405 KSSK------TILDYVWdqYPL----MNEKDIRAVLGRF--------LFVQDDVKKIindLSGGEKARLQLALLMLQRDN 466
Cdd:COG4178 431 LPQRpylplgTLREALL--YPAtaeaFSDAELREALEAVglghlaerLDEEADWDQV---LSLGEQQRLAFARLLLHKPD 505
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 446524717 467 VLILDEPTNHLDIDSKEMLEQALQH--FEGTILFVSHdRYFINQLANKVFDLTIDGG 521
Cdd:COG4178 506 WLFLDEATSALDEENEAALYQLLREelPGTTVISVGH-RSTLAAFHDRVLELTGDGS 561
|
|
| ABC_cobalt_CbiO_domain2 |
cd03226 |
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of ... |
8-242 |
4.03e-14 |
|
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. The CbiMNQO family ABC transport system is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.
Pssm-ID: 213193 [Multi-domain] Cd Length: 205 Bit Score: 71.52 E-value: 4.03e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 8 HISKSF-DGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNVS----KIKNLKL----GYLTQQMT-- 76
Cdd:cd03226 4 NISFSYkKGTEILDDLSLDLYAGEIIALTGKNGAGKTTLAKILAGLIKESSGSILlngkPIKAKERrksiGYVMQDVDyq 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 77 LNSNaTVFEEMskpfehikrmeslikeetdwlskhandydsdtykthmsrYESLSNqfeqleGYQYESKIKTVLHGLNFS 156
Cdd:cd03226 84 LFTD-SVREEL---------------------------------------LLGLKE------LDAGNEQAETVLKDLDLY 117
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 157 EEDFNKPInDFSGGQKTRLSLAQMLLNEPDLLLLDEPTNHLDLETTKWLEDYLRYFKG---AIVIISHDRYFLDKIVTQI 233
Cdd:cd03226 118 ALKERHPL-SLSGGQKQRLAIAAALLSGKDLLIFDEPTSGLDYKNMERVGELIRELAAqgkAVIVITHDYEFLAKVCDRV 196
|
....*....
gi 446524717 234 YDVALGDVK 242
Cdd:cd03226 197 LLLANGAIV 205
|
|
| ABC_CysA_sulfate_importer |
cd03296 |
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex ... |
348-513 |
5.92e-14 |
|
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex cysAWTP involved in sulfate import. Responsible for energy coupling to the transport system. The complex is composed of two ATP-binding proteins (cysA), two transmembrane proteins (cysT and cysW), and a solute-binding protein (cysP). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213263 [Multi-domain] Cd Length: 239 Bit Score: 71.99 E-value: 5.92e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 348 ISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITFGA---------NLQIGYYDQKQAEFKsSKTILDYVW--- 415
Cdd:cd03296 21 VSLDIPSGELVALLGPSGSGKTTLLRLIAGLERPDSGTILFGGedatdvpvqERNVGFVFQHYALFR-HMTVFDNVAfgl 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 416 -----DQYPlmNEKDIRAVLGRFL-FVQDD--VKKIINDLSGGEKARLQLALLMLQRDNVLILDEPTNHLDIDSKEMLEQ 487
Cdd:cd03296 100 rvkprSERP--PEAEIRAKVHELLkLVQLDwlADRYPAQLSGGQRQRVALARALAVEPKVLLLDEPFGALDAKVRKELRR 177
|
170 180 190
....*....|....*....|....*....|
gi 446524717 488 ALQHFEG----TILFVSHDRYFINQLANKV 513
Cdd:cd03296 178 WLRRLHDelhvTTVFVTHDQEEALEVADRV 207
|
|
| PLN03073 |
PLN03073 |
ABC transporter F family; Provisional |
15-251 |
7.12e-14 |
|
ABC transporter F family; Provisional
Pssm-ID: 215558 [Multi-domain] Cd Length: 718 Bit Score: 74.90 E-value: 7.12e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 15 GEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNVSKIKNLKLGYLTQQ----MTLNSNATVFeeMSKP 90
Cdd:PLN03073 521 GPLLFKNLNFGIDLDSRIAMVGPNGIGKSTILKLISGELQPSSGTVFRSAKVRMAVFSQHhvdgLDLSSNPLLY--MMRC 598
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 91 FEHIKrmeslikeetdwlskhandydsdtykthmsryeslsnqfeqlegyqyESKIKTVLHGLNFSEEDFNKPINDFSGG 170
Cdd:PLN03073 599 FPGVP-----------------------------------------------EQKLRAHLGSFGVTGNLALQPMYTLSGG 631
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 171 QKTRLSLAQMLLNEPDLLLLDEPTNHLDLETTKWLEDYLRYFKGAIVIISHDRYFLDKIVTQIYDVALGDVKRYVGNYEE 250
Cdd:PLN03073 632 QKSRVAFAKITFKKPHILLLDEPSNHLDLDAVEALIQGLVLFQGGVLMVSHDEHLISGSVDELWVVSEGKVTPFHGTFHD 711
|
.
gi 446524717 251 F 251
Cdd:PLN03073 712 Y 712
|
|
| YhaQ |
COG4152 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
4-61 |
9.03e-14 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 443322 [Multi-domain] Cd Length: 298 Bit Score: 72.45 E-value: 9.03e-14
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 446524717 4 LQLNHISKSFDGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNVS 61
Cdd:COG4152 2 LELKGLTKRFGDKTAVDDVSFTVPKGEIFGLLGPNGAGKTTTIRIILGILAPDSGEVL 59
|
|
| LolD |
COG1136 |
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis]; |
3-85 |
9.48e-14 |
|
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440751 [Multi-domain] Cd Length: 227 Bit Score: 70.84 E-value: 9.48e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 3 LLQLNHISKSF-DGEDIFT---DVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNV---------------SKI 63
Cdd:COG1136 4 LLELRNLTKSYgTGEGEVTalrGVSLSIEAGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVlidgqdisslserelARL 83
|
90 100
....*....|....*....|..
gi 446524717 64 KNLKLGYLTQQMTLNSNATVFE 85
Cdd:COG1136 84 RRRHIGFVFQFFNLLPELTALE 105
|
|
| ABC_subfamily_A |
cd03263 |
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily ... |
4-222 |
1.04e-13 |
|
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily mediates the transport of a variety of lipid compounds. Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency, degenerative retinopathies, and congenital keratinization disorders. The ABCA1 protein is involved in disorders of cholesterol transport and high-density lipoprotein (HDL) biosynthesis. The ABCA4 (ABCR) protein transports vitamin A derivatives in the outer segments of photoreceptor cells, and therefore, performs a crucial step in the visual cycle. The ABCA genes are not present in yeast. However, evolutionary studies of ABCA genes indicate that they arose as transporters that subsequently duplicated and that certain sets of ABCA genes were lost in different eukaryotic lineages.
Pssm-ID: 213230 [Multi-domain] Cd Length: 220 Bit Score: 70.61 E-value: 1.04e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 4 LQLNHISKSFdGEDIFT---DVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNV-----SKIKNLK-----LGY 70
Cdd:cd03263 1 LQIRNLTKTY-KKGTKPavdDLSLNVYKGEIFGLLGHNGAGKTTTLKMLTGELRPTSGTAyingySIRTDRKaarqsLGY 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 71 LTQQMTLnsnatvFEEMSkPFEHIKRMeSLIKEetdwLSKHANDYDSDTYKTHMSryeslsnqfeqLEGYQyeskiktvl 150
Cdd:cd03263 80 CPQFDAL------FDELT-VREHLRFY-ARLKG----LPKSEIKEEVELLLRVLG-----------LTDKA--------- 127
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446524717 151 hglnfseedfNKPINDFSGGQKTRLSLAQMLLNEPDLLLLDEPTNHLDLETTKWLEDYLRYFKG--AIVIISHD 222
Cdd:cd03263 128 ----------NKRARTLSGGMKRKLSLAIALIGGPSVLLLDEPTSGLDPASRRAIWDLILEVRKgrSIILTTHS 191
|
|
| ABC_PotA_N |
cd03300 |
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and ... |
333-502 |
1.16e-13 |
|
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and the ATPase component of the spermidine/putrescine-preferential uptake system consisting of PotA, -B, -C, and -D. PotA has two domains with the N-terminal domain containing the ATPase activity and the residues required for homodimerization with PotA and heterdimerization with PotB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213267 [Multi-domain] Cd Length: 232 Bit Score: 70.73 E-value: 1.16e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 333 VKNLEIGY-QTAITKPISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITFG----ANL-----QIGYYDQKQA 402
Cdd:cd03300 3 LENVSKFYgGFVALDGVSLDIKEGEFFTLLGPSGCGKTTLLRLIAGFETPTSGEILLDgkdiTNLpphkrPVNTVFQNYA 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 403 EFKSsktiLDyVWDQ--YPL----MNEKDIRAVLGRFL-FVQ--DDVKKIINDLSGGEKARLQLALLMLQRDNVLILDEP 473
Cdd:cd03300 83 LFPH----LT-VFENiaFGLrlkkLPKAEIKERVAEALdLVQleGYANRKPSQLSGGQQQRVAIARALVNEPKVLLLDEP 157
|
170 180 190
....*....|....*....|....*....|...
gi 446524717 474 TNHLDID-SKEMLEQ--ALQHFEG-TILFVSHD 502
Cdd:cd03300 158 LGALDLKlRKDMQLElkRLQKELGiTFVFVTHD 190
|
|
| ABC_Mj1267_LivG_branched |
cd03219 |
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ... |
348-513 |
1.23e-13 |
|
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ABC transporter subfamily is involved in the transport of the hydrophobic amino acids leucine, isoleucine and valine. MJ1267 is a branched-chain amino acid transporter with 29% similarity to both the LivF and LivG components of the E. coli branched-chain amino acid transporter. MJ1267 contains an insertion from residues 114 to 123 characteristic of LivG (Leucine-Isoleucine-Valine) homologs. The branched-chain amino acid transporter from E. coli comprises a heterodimer of ABCs (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ).
Pssm-ID: 213186 [Multi-domain] Cd Length: 236 Bit Score: 70.93 E-value: 1.23e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 348 ISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITFG------------ANLQIGYYDQKQAEFKSSkTILD--- 412
Cdd:cd03219 19 VSFSVRPGEIHGLIGPNGAGKTTLFNLISGFLRPTSGSVLFDgeditglppheiARLGIGRTFQIPRLFPEL-TVLEnvm 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 413 ---------YVWDQYPLMNEKDIRA----VLgRFLFVQDDVKKIINDLSGGEKARLQLALLMLQRDNVLILDEPT---NH 476
Cdd:cd03219 98 vaaqartgsGLLLARARREEREAREraeeLL-ERVGLADLADRPAGELSYGQQRRLEIARALATDPKLLLLDEPAaglNP 176
|
170 180 190
....*....|....*....|....*....|....*....
gi 446524717 477 LDIDskEMLE--QALQHFEGTILFVSHDRYFINQLANKV 513
Cdd:cd03219 177 EETE--ELAEliRELRERGITVLLVEHDMDVVMSLADRV 213
|
|
| ABC_NrtD_SsuB_transporters |
cd03293 |
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ... |
4-77 |
1.32e-13 |
|
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ATP-binding subunits of the bacterial ABC-type nitrate and sulfonate transport systems, respectively. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213260 [Multi-domain] Cd Length: 220 Bit Score: 70.19 E-value: 1.32e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 4 LQLNHISKSFDGED----IFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNVS----KIK--NLKLGYLTQ 73
Cdd:cd03293 1 LEVRNVSKTYGGGGgavtALEDISLSVEEGEFVALVGPSGCGKSTLLRIIAGLERPTSGEVLvdgePVTgpGPDRGYVFQ 80
|
....
gi 446524717 74 QMTL 77
Cdd:cd03293 81 QDAL 84
|
|
| MalK |
COG3839 |
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism]; ... |
1-60 |
1.37e-13 |
|
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism];
Pssm-ID: 443050 [Multi-domain] Cd Length: 352 Bit Score: 72.41 E-value: 1.37e-13
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 1 MILLQLNHISKSFDGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNV 60
Cdd:COG3839 1 MASLELENVSKSYGGVEALKDIDLDIEDGEFLVLLGPSGCGKSTLLRMIAGLEDPTSGEI 60
|
|
| bacteriocin_ABC |
TIGR01193 |
ABC-type bacteriocin transporter; This model describes ABC-type bacteriocin transporter. The ... |
339-523 |
1.44e-13 |
|
ABC-type bacteriocin transporter; This model describes ABC-type bacteriocin transporter. The amino terminal domain (pfam03412) processes the N-terminal leader peptide from the bacteriocin while C-terminal domains resemble ABC transporter membrane protein and ATP-binding cassette domain. In general, bacteriocins are agents which are responsible for killing or inhibiting the closely related species or even different strains of the same species. Bacteriocins are usually encoded by bacterial plasmids. Bacteriocins are named after the species and hence in literature one encounters various names e.g., leucocin from Leuconostic geldium; pedicocin from Pedicoccus acidilactici; sakacin from Lactobacillus sake etc. [Protein fate, Protein and peptide secretion and trafficking, Protein fate, Protein modification and repair, Transport and binding proteins, Other]
Pssm-ID: 130261 [Multi-domain] Cd Length: 708 Bit Score: 74.01 E-value: 1.44e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 339 GYQTAITKPISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITFG----ANLQIGYYDQ-----KQAEFKSSKT 409
Cdd:TIGR01193 484 GYGSNILSDISLTIKMNSKTTIVGMSGSGKSTLAKLLVGFFQARSGEILLNgfslKDIDRHTLRQfinylPQEPYIFSGS 563
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 410 ILD-YVWDQYPLMNEKDIRAVLgRFLFVQDDVKKII-----------NDLSGGEKARLQLALLMLQRDNVLILDEPTNHL 477
Cdd:TIGR01193 564 ILEnLLLGAKENVSQDEIWAAC-EIAEIKDDIENMPlgyqtelseegSSISGGQKQRIALARALLTDSKVLILDESTSNL 642
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 446524717 478 D-IDSKEMLEQALQHFEGTILFVSHdRYFINQLANKVfdLTIDGGKM 523
Cdd:TIGR01193 643 DtITEKKIVNNLLNLQDKTIIFVAH-RLSVAKQSDKI--IVLDHGKI 686
|
|
| ABCC_MRP_Like |
cd03228 |
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP ... |
4-77 |
1.61e-13 |
|
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP (Multidrug Resistance Protein)-like transporters are involved in drug, peptide, and lipid export. They belong to the subfamily C of the ATP-binding cassette (ABC) superfamily of transport proteins. The ABCC subfamily contains transporters with a diverse functional spectrum that includes ion transport, cell surface receptor, and toxin secretion activities. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains, each composed of six transmembrane (TM) helices, and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213195 [Multi-domain] Cd Length: 171 Bit Score: 68.95 E-value: 1.61e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 4 LQLNHISKSFDGED--IFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNVS----KIKNLKLGYLTQQMTL 77
Cdd:cd03228 1 IEFKNVSFSYPGRPkpVLKDVSLTIKPGEKVAIVGPSGSGKSTLLKLLLRLYDPTSGEILidgvDLRDLDLESLRKNIAY 80
|
|
| ABC_FtsE |
cd03292 |
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where ... |
348-523 |
1.66e-13 |
|
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages
Pssm-ID: 213259 [Multi-domain] Cd Length: 214 Bit Score: 70.13 E-value: 1.66e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 348 ISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITF-GANL------QIGYYDQKQA-EFKSSKTILDY-VWDQY 418
Cdd:cd03292 20 INISISAGEFVFLVGPSGAGKSTLLKLIYKEELPTSGTIRVnGQDVsdlrgrAIPYLRRKIGvVFQDFRLLPDRnVYENV 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 419 PLMNE------KDIR----AVLgRFLFVQDDVKKIINDLSGGEKARLQLALLMLQRDNVLILDEPTNHLDIDSKEMLEQA 488
Cdd:cd03292 100 AFALEvtgvppREIRkrvpAAL-ELVGLSHKHRALPAELSGGEQQRVAIARAIVNSPTILIADEPTGNLDPDTTWEIMNL 178
|
170 180 190
....*....|....*....|....*....|....*...
gi 446524717 489 LQHFE---GTILFVSHDRYFINQLANKVfdLTIDGGKM 523
Cdd:cd03292 179 LKKINkagTTVVVATHAKELVDTTRHRV--IALERGKL 214
|
|
| PhnL |
COG4778 |
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion ... |
348-517 |
1.76e-13 |
|
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion transport and metabolism];
Pssm-ID: 443809 [Multi-domain] Cd Length: 229 Bit Score: 70.16 E-value: 1.76e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 348 ISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITFGANLQ-------------------IGY------------ 396
Cdd:COG4778 30 VSFSVAAGECVALTGPSGAGKSTLLKCIYGNYLPDSGSILVRHDGGwvdlaqaspreilalrrrtIGYvsqflrviprvs 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 397 -------------YDQKQAEFKSsKTILDY------VWDQYPlmnekdiravlgrflfvqddvkkiiNDLSGGEKARLQL 457
Cdd:COG4778 110 aldvvaepllergVDREEARARA-RELLARlnlperLWDLPP-------------------------ATFSGGEQQRVNI 163
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446524717 458 ALLMLQRDNVLILDEPTNHLDIDSK----EMLEQALQhfEGT-ILFVSHDRYFINQLANKVFDLT 517
Cdd:COG4778 164 ARGFIADPPLLLLDEPTASLDAANRavvvELIEEAKA--RGTaIIGIFHDEEVREAVADRVVDVT 226
|
|
| LivF |
COG0410 |
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid ... |
333-474 |
1.76e-13 |
|
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid transport and metabolism];
Pssm-ID: 440179 [Multi-domain] Cd Length: 236 Bit Score: 70.40 E-value: 1.76e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 333 VKNLEIGY-QTAITKPISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITF-GA-------------------- 390
Cdd:COG0410 6 VENLHAGYgGIHVLHGVSLEVEEGEIVALLGRNGAGKTTLLKAISGLLPPRSGSIRFdGEditglpphriarlgigyvpe 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 391 ------------NLQIGYYDQKQAEfkSSKTILDYVWDQYPLMNEKdiRAVLGrflfvqddvkkiiNDLSGGEkaRLQLA 458
Cdd:COG0410 86 grrifpsltveeNLLLGAYARRDRA--EVRADLERVYELFPRLKER--RRQRA-------------GTLSGGE--QQMLA 146
|
170
....*....|....*....
gi 446524717 459 L---LMLQRDnVLILDEPT 474
Cdd:COG0410 147 IgraLMSRPK-LLLLDEPS 164
|
|
| ABC_tran_CTD |
pfam16326 |
ABC transporter C-terminal domain; This domain is found at the C-terminus of ABC transporters. ... |
568-639 |
1.88e-13 |
|
ABC transporter C-terminal domain; This domain is found at the C-terminus of ABC transporters. It has a coiled coil structure with an atypical 3(10)-helix in the alpha-hairpin region. It is involved in DNA_binding.
Pssm-ID: 465095 [Multi-domain] Cd Length: 69 Bit Score: 65.57 E-value: 1.88e-13
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446524717 568 KEQRREQRKLErqisECENEIETLETTILQIDEQLTQPEVYNNPQKANELAIQKQDSEQKLEHAMSKWEELQ 639
Cdd:pfam16326 1 KLSYKEQRELE----ELEAEIEKLEEEIAELEAQLADPELYSDYEKLQELSAELEELEAELEELYERWEELE 68
|
|
| ABC_ModC_molybdenum_transporter |
cd03297 |
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type ... |
354-502 |
2.03e-13 |
|
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213264 [Multi-domain] Cd Length: 214 Bit Score: 69.63 E-value: 2.03e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 354 KGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITFGANL---------------QIGYYDQKQAEFK--SSKTILDYVWD 416
Cdd:cd03297 22 NEEVTGIFGASGAGKSTLLRCIAGLEKPDGGTIVLNGTVlfdsrkkinlppqqrKIGLVFQQYALFPhlNVRENLAFGLK 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 417 QYPLMNEKD-IRAVLGRFlFVQDDVKKIINDLSGGEKARLQLALLMLQRDNVLILDEPTNHLDIDSKEMLEQAL----QH 491
Cdd:cd03297 102 RKRNREDRIsVDELLDLL-GLDHLLNRYPAQLSGGEKQRVALARALAAQPELLLLDEPFSALDRALRLQLLPELkqikKN 180
|
170
....*....|.
gi 446524717 492 FEGTILFVSHD 502
Cdd:cd03297 181 LNIPVIFVTHD 191
|
|
| MlaF |
COG1127 |
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall ... |
3-85 |
2.14e-13 |
|
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440744 [Multi-domain] Cd Length: 241 Bit Score: 70.01 E-value: 2.14e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 3 LLQLNHISKSFDGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNV------------SKIKNL--KL 68
Cdd:COG1127 5 MIEVRNLTKSFGDRVVLDGVSLDVPRGEILAIIGGSGSGKSVLLKLIIGLLRPDSGEIlvdgqditglseKELYELrrRI 84
|
90
....*....|....*..
gi 446524717 69 GYLTQQMTLNSNATVFE 85
Cdd:COG1127 85 GMLFQGGALFDSLTVFE 101
|
|
| ABC_subfamily_A |
cd03263 |
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily ... |
331-530 |
2.32e-13 |
|
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily mediates the transport of a variety of lipid compounds. Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency, degenerative retinopathies, and congenital keratinization disorders. The ABCA1 protein is involved in disorders of cholesterol transport and high-density lipoprotein (HDL) biosynthesis. The ABCA4 (ABCR) protein transports vitamin A derivatives in the outer segments of photoreceptor cells, and therefore, performs a crucial step in the visual cycle. The ABCA genes are not present in yeast. However, evolutionary studies of ABCA genes indicate that they arose as transporters that subsequently duplicated and that certain sets of ABCA genes were lost in different eukaryotic lineages.
Pssm-ID: 213230 [Multi-domain] Cd Length: 220 Bit Score: 69.84 E-value: 2.32e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 331 MHVKNL----EIGYQTAItKPISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITF-GANLQ---------IGY 396
Cdd:cd03263 1 LQIRNLtktyKKGTKPAV-DDLSLNVYKGEIFGLLGHNGAGKTTTLKMLTGELRPTSGTAYInGYSIRtdrkaarqsLGY 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 397 YDQKQAEFKSSkTILDYVWdqypLM------NEKDIRAVLGRFLFV---QDDVKKIINDLSGGEKARLQLALLMLQRDNV 467
Cdd:cd03263 80 CPQFDALFDEL-TVREHLR----FYarlkglPKSEIKEEVELLLRVlglTDKANKRARTLSGGMKRKLSLAIALIGGPSV 154
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446524717 468 LILDEPTNHLDIDSKEMLEQALQHFEG--TILFVSHDRYFINQLANKVFDLTiDGGKMYLGDYQY 530
Cdd:cd03263 155 LLLDEPTSGLDPASRRAIWDLILEVRKgrSIILTTHSMDEAEALCDRIAIMS-DGKLRCIGSPQE 218
|
|
| NupO |
COG3845 |
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ... |
3-58 |
2.52e-13 |
|
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];
Pssm-ID: 443055 [Multi-domain] Cd Length: 504 Bit Score: 72.75 E-value: 2.52e-13
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 446524717 3 LLQLNHISKSFDGediFT---DVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSG 58
Cdd:COG3845 5 ALELRGITKRFGG---VVandDVSLTVRPGEIHALLGENGAGKSTLMKILYGLYQPDSG 60
|
|
| PRK11160 |
PRK11160 |
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed |
333-529 |
2.74e-13 |
|
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
Pssm-ID: 236865 [Multi-domain] Cd Length: 574 Bit Score: 72.94 E-value: 2.74e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 333 VKNLEIGY---QTAITKPISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITFGA------------------- 390
Cdd:PRK11160 341 LNNVSFTYpdqPQPVLKGLSLQIKAGEKVALLGRTGCGKSTLLQLLTRAWDPQQGEILLNGqpiadyseaalrqaisvvs 420
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 391 ------------NLQIGyydQKQAEFKSSKTILDYVWDQYPLMNEKDIRAVLG---RflfvqddvkkiinDLSGGEKARL 455
Cdd:PRK11160 421 qrvhlfsatlrdNLLLA---APNASDEALIEVLQQVGLEKLLEDDKGLNAWLGeggR-------------QLSGGEQRRL 484
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446524717 456 QLALLMLQRDNVLILDEPTNHLDIDS-KEMLEQALQHFEG-TILFVSHDRYFINQlankvFDLT--IDGGK-MYLGDYQ 529
Cdd:PRK11160 485 GIARALLHDAPLLLLDEPTEGLDAETeRQILELLAEHAQNkTVLMITHRLTGLEQ-----FDRIcvMDNGQiIEQGTHQ 558
|
|
| sufC |
TIGR01978 |
FeS assembly ATPase SufC; SufC is part of the SUF system, shown in E. coli to consist of six ... |
4-229 |
3.09e-13 |
|
FeS assembly ATPase SufC; SufC is part of the SUF system, shown in E. coli to consist of six proteins and believed to act in Fe-S cluster formation during oxidative stress. SufC forms a complex with SufB and SufD. SufC belongs to the ATP-binding cassette transporter family (pfam00005) but is no longer thought to be part of a transporter. The complex is reported as cytosolic () or associated with the membrane (). The SUF system also includes a cysteine desulfurase (SufS, enhanced by SufE) and a probable iron-sulfur cluster assembly scaffold protein, SufA. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other]
Pssm-ID: 273907 [Multi-domain] Cd Length: 243 Bit Score: 69.98 E-value: 3.09e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 4 LQLNHISKSFDGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYD--SGNVskikNLKlGYLTQQMTLN--S 79
Cdd:TIGR01978 1 LKIKDLHVSVEDKEILKGVNLTVKKGEIHAIMGPNGSGKSTLSKTIAGHPSYEvtSGTI----LFK-GQDLLELEPDerA 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 80 NATVFEEMSKPFEhIK--RMESLIKEETDWLSKHANDydsdtykthmsryeslsnqfEQLEGYQYESKIKTVLHGLNFSE 157
Cdd:TIGR01978 76 RAGLFLAFQYPEE-IPgvSNLEFLRSALNARRSARGE--------------------EPLDLLDFEKLLKEKLALLDMDE 134
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446524717 158 EDFNKPIND-FSGGQKTRLSLAQMLLNEPDLLLLDEPTNHLDLETTKWLEDYLRYFKG---AIVIISHDRYFLDKI 229
Cdd:TIGR01978 135 EFLNRSVNEgFSGGEKKRNEILQMALLEPKLAILDEIDSGLDIDALKIVAEGINRLREpdrSFLIITHYQRLLNYI 210
|
|
| CydC |
TIGR02868 |
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family ... |
348-502 |
3.30e-13 |
|
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex.
Pssm-ID: 274331 [Multi-domain] Cd Length: 530 Bit Score: 72.39 E-value: 3.30e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 348 ISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITF-GANLQ----------IGYYDQKQAEFKSskTILDYVWD 416
Cdd:TIGR02868 354 VSLDLPPGERVAILGPSGSGKSTLLATLAGLLDPLQGEVTLdGVPVSsldqdevrrrVSVCAQDAHLFDT--TVRENLRL 431
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 417 QYPLMNEKDIRAVLGRflfVQ---------DDVKKIIND----LSGGEKARLQLALLMLQRDNVLILDEPTNHLDID-SK 482
Cdd:TIGR02868 432 ARPDATDEELWAALER---VGladwlralpDGLDTVLGEggarLSGGERQRLALARALLADAPILLLDEPTEHLDAEtAD 508
|
170 180
....*....|....*....|.
gi 446524717 483 EMLEQALQHFEG-TILFVSHD 502
Cdd:TIGR02868 509 ELLEDLLAALSGrTVVLITHH 529
|
|
| ABC_NikE_OppD_transporters |
cd03257 |
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter ... |
3-230 |
3.54e-13 |
|
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter subfamily specific for the transport of dipeptides, oligopeptides (OppD), and nickel (NikDE). The NikABCDE system of E. coli belongs to this family and is composed of the periplasmic binding protein NikA, two integral membrane components (NikB and NikC), and two ATPase (NikD and NikE). The NikABCDE transporter is synthesized under anaerobic conditions to meet the increased demand for nickel resulting from hydrogenase synthesis. The molecular mechanism of nickel uptake in many bacteria and most archaea is not known. Many other members of this ABC family are also involved in the uptake of dipeptides and oligopeptides. The oligopeptide transport system (Opp) is a five-component ABC transport composed of a membrane-anchored substrate binding proteins (SRP), OppA, two transmembrane proteins, OppB and OppC, and two ATP-binding domains, OppD and OppF.
Pssm-ID: 213224 [Multi-domain] Cd Length: 228 Bit Score: 69.46 E-value: 3.54e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 3 LLQLNHISKSFDGEDIFT----DVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNVsKIKNLKLGYLTQQMTL- 77
Cdd:cd03257 1 LLEVKNLSVSFPTGGGSVkaldDVSFSIKKGETLGLVGESGSGKSTLARAILGLLKPTSGSI-IFDGKDLLKLSRRLRKi 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 78 --NSNATVFEE-MSK--PfehIKRMESLIKEEtdwLSKHANDYDSDTYKThmsryeslsnqfeqlegyqyesKIKTVLHG 152
Cdd:cd03257 80 rrKEIQMVFQDpMSSlnP---RMTIGEQIAEP---LRIHGKLSKKEARKE----------------------AVLLLLVG 131
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 153 LNFSEEDFNKPINDFSGGQKTRLSLAQMLLNEPDLLLLDEPTNHLDLeTTKW-----LEDYLRYFKGAIVIISHD----R 223
Cdd:cd03257 132 VGLPEEVLNRYPHELSGGQRQRVAIARALALNPKLLIADEPTSALDV-SVQAqildlLKKLQEELGLTLLFITHDlgvvA 210
|
....*..
gi 446524717 224 YFLDKIV 230
Cdd:cd03257 211 KIADRVA 217
|
|
| LivG |
COG0411 |
ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid ... |
1-60 |
5.71e-13 |
|
ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid transport and metabolism];
Pssm-ID: 440180 [Multi-domain] Cd Length: 257 Bit Score: 69.30 E-value: 5.71e-13
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 1 MILLQLNHISKSFDGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNV 60
Cdd:COG0411 2 DPLLEVRGLTKRFGGLVAVDDVSLEVERGEIVGLIGPNGAGKTTLFNLITGFYRPTSGRI 61
|
|
| ABC_NatA_sodium_exporter |
cd03266 |
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a ... |
3-221 |
5.99e-13 |
|
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of a single ATP-binding protein and a single integral membrane protein.
Pssm-ID: 213233 [Multi-domain] Cd Length: 218 Bit Score: 68.55 E-value: 5.99e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 3 LLQLNHISKSFDGEDIFT----DVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNvskiknlklgyltqqmtln 78
Cdd:cd03266 1 MITADALTKRFRDVKKTVqavdGVSFTVKPGEVTGLLGPNGAGKTTTLRMLAGLLEPDAGF------------------- 61
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 79 snATV--FEEMSKPFEHIKRMESLIKEET--DWLSKHAN-DYDSDTYKthmsryeslsnqfeqLEGYQYESKIKTVLHGL 153
Cdd:cd03266 62 --ATVdgFDVVKEPAEARRRLGFVSDSTGlyDRLTARENlEYFAGLYG---------------LKGDELTARLEELADRL 124
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446524717 154 NFsEEDFNKPINDFSGGQKTRLSLAQMLLNEPDLLLLDEPTNHLDLETTKWLEDYLRYFKG---AIVIISH 221
Cdd:cd03266 125 GM-EELLDRRVGGFSTGMRQKVAIARALVHDPPVLLLDEPTTGLDVMATRALREFIRQLRAlgkCILFSTH 194
|
|
| ABC_CysA_sulfate_importer |
cd03296 |
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex ... |
4-222 |
6.28e-13 |
|
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex cysAWTP involved in sulfate import. Responsible for energy coupling to the transport system. The complex is composed of two ATP-binding proteins (cysA), two transmembrane proteins (cysT and cysW), and a solute-binding protein (cysP). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213263 [Multi-domain] Cd Length: 239 Bit Score: 68.91 E-value: 6.28e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 4 LQLNHISKSFDGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNV---------SKIKNLKLGYLTQQ 74
Cdd:cd03296 3 IEVRNVSKRFGDFVALDDVSLDIPSGELVALLGPSGSGKTTLLRLIAGLERPDSGTIlfggedatdVPVQERNVGFVFQH 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 75 MTLNSNATVFEEMSKPFEHIKRMESLIKEETDwlskhandydsdtykthmSRYESLSnQFEQLEGYQyeskiktvlhgln 154
Cdd:cd03296 83 YALFRHMTVFDNVAFGLRVKPRSERPPEAEIR------------------AKVHELL-KLVQLDWLA------------- 130
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446524717 155 fseedfNKPINDFSGGQKTRLSLAQMLLNEPDLLLLDEPTNHLDLETTKWLEDYLRYFKGAI----VIISHD 222
Cdd:cd03296 131 ------DRYPAQLSGGQRQRVALARALAVEPKVLLLDEPFGALDAKVRKELRRWLRRLHDELhvttVFVTHD 196
|
|
| PRK10253 |
PRK10253 |
iron-enterobactin ABC transporter ATP-binding protein; |
334-508 |
7.73e-13 |
|
iron-enterobactin ABC transporter ATP-binding protein;
Pssm-ID: 182336 [Multi-domain] Cd Length: 265 Bit Score: 69.24 E-value: 7.73e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 334 KNLEIGY-QTAITKPISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITF-GANLQ----------IGYYDQkQ 401
Cdd:PRK10253 11 EQLTLGYgKYTVAENLTVEIPDGHFTAIIGPNGCGKSTLLRTLSRLMTPAHGHVWLdGEHIQhyaskevarrIGLLAQ-N 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 402 AEFKSSKTILDYV----WDQYPLMN---EKDIRAVLG--RFLFVQDDVKKIINDLSGGEKARLQLALLMLQRDNVLILDE 472
Cdd:PRK10253 90 ATTPGDITVQELVargrYPHQPLFTrwrKEDEEAVTKamQATGITHLADQSVDTLSGGQRQRAWIAMVLAQETAIMLLDE 169
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 446524717 473 PTNHLD----IDSKEMLEQALQHFEGTILFVSHDryfINQ 508
Cdd:PRK10253 170 PTTWLDishqIDLLELLSELNREKGYTLAAVLHD---LNQ 206
|
|
| YbbA |
COG4181 |
Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase ... |
3-60 |
9.97e-13 |
|
Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 443338 [Multi-domain] Cd Length: 233 Bit Score: 68.23 E-value: 9.97e-13
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446524717 3 LLQLNHISKSFDGE----DIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNV 60
Cdd:COG4181 8 IIELRGLTKTVGTGagelTILKGISLEVEAGESVAIVGASGSGKSTLLGLLAGLDRPTSGTV 69
|
|
| ModF |
COG1119 |
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA ... |
1-85 |
1.30e-12 |
|
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA [Inorganic ion transport and metabolism];
Pssm-ID: 440736 [Multi-domain] Cd Length: 250 Bit Score: 68.19 E-value: 1.30e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 1 MILLQLNHISKSFDGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGvENY-DSGN-------------VSKIKNl 66
Cdd:COG1119 1 DPLLELRNVTVRRGGKTILDDISWTVKPGEHWAILGPNGAGKSTLLSLITG-DLPpTYGNdvrlfgerrggedVWELRK- 78
|
90 100
....*....|....*....|.
gi 446524717 67 KLGYLTQQMTLN--SNATVFE 85
Cdd:COG1119 79 RIGLVSPALQLRfpRDETVLD 99
|
|
| ABC_PstB_phosphate_transporter |
cd03260 |
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of ... |
333-502 |
1.69e-12 |
|
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of fundamental importance in the cell physiology of bacteria because phosphate is required as a nutrient. The Pst system of E. coli comprises four distinct subunits encoded by the pstS, pstA, pstB, and pstC genes. The PstS protein is a phosphate-binding protein located in the periplasmic space. PstA and PstC are hydrophobic and they form the transmembrane portion of the Pst system. PstB is the catalytic subunit, which couples the energy of ATP hydrolysis to the import of phosphate across cellular membranes through the Pst system, often referred as ABC-protein. PstB belongs to one of the largest superfamilies of proteins characterized by a highly conserved adenosine triphosphate (ATP) binding cassette (ABC), which is also a nucleotide binding domain (NBD).
Pssm-ID: 213227 [Multi-domain] Cd Length: 227 Bit Score: 67.21 E-value: 1.69e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 333 VKNLEIGY-QTAITKPISIEVSKGDHIAIIGPNGIGKSTLIKTIA-----NQQKALNGYITF-GANL------------Q 393
Cdd:cd03260 3 LRDLNVYYgDKHALKDISLDIPKGEITALIGPSGCGKSTLLRLLNrlndlIPGAPDEGEVLLdGKDIydldvdvlelrrR 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 394 IGYYDQKQAEFksSKTILDYVwdQYPL----MNEKDIRAVLGRFLF----VQDDVKKIIN--DLSGGEKARLQLALLMLQ 463
Cdd:cd03260 83 VGMVFQKPNPF--PGSIYDNV--AYGLrlhgIKLKEELDERVEEALrkaaLWDEVKDRLHalGLSGGQQQRLCLARALAN 158
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 446524717 464 RDNVLILDEPTNHLDIDSKEMLEQALQHF--EGTILFVSHD 502
Cdd:cd03260 159 EPEVLLLDEPTSALDPISTAKIEELIAELkkEYTIVIVTHN 199
|
|
| znuC |
PRK09544 |
high-affinity zinc transporter ATPase; Reviewed |
329-502 |
1.86e-12 |
|
high-affinity zinc transporter ATPase; Reviewed
Pssm-ID: 181939 [Multi-domain] Cd Length: 251 Bit Score: 67.83 E-value: 1.86e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 329 DVMHVKNLEIGY-QTAITKPISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITFGANLQIGYYDQKQAEFKSS 407
Cdd:PRK09544 3 SLVSLENVSVSFgQRRVLSDVSLELKPGKILTLLGPNGAGKSTLVRVVLGLVAPDEGVIKRNGKLRIGYVPQKLYLDTTL 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 408 KTILDYVWDQYPLMNEKDIRAVLGRflfVQDD--VKKIINDLSGGEKARLQLALLMLQRDNVLILDEPTNHLDIDSK--- 482
Cdd:PRK09544 83 PLTVNRFLRLRPGTKKEDILPALKR---VQAGhlIDAPMQKLSGGETQRVLLARALLNRPQLLVLDEPTQGVDVNGQval 159
|
170 180
....*....|....*....|.
gi 446524717 483 -EMLEQALQHFEGTILFVSHD 502
Cdd:PRK09544 160 yDLIDQLRRELDCAVLMVSHD 180
|
|
| ABCC_bacteriocin_exporters |
cd03245 |
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic ... |
4-233 |
1.94e-12 |
|
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic bacteriocins of lactic acid bacteria are produced as precursors which have N-terminal leader peptides that share similarities in amino acid sequence and contain a conserved processing site of two glycine residues in positions -1 and -2. A dedicated ATP-binding cassette (ABC) transporter is responsible for the proteolytic cleavage of the leader peptides and subsequent translocation of the bacteriocins across the cytoplasmic membrane.
Pssm-ID: 213212 [Multi-domain] Cd Length: 220 Bit Score: 66.84 E-value: 1.94e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 4 LQLNHISKSFDGEDIFT--DVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNVS----KIKNL-------KLGY 70
Cdd:cd03245 3 IEFRNVSFSYPNQEIPAldNVSLTIRAGEKVAIIGRVGSGKSTLLKLLAGLYKPTSGSVLldgtDIRQLdpadlrrNIGY 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 71 LTQQMTLNSnATVFE--EMSKPFEHIKRMESLIKEE--TDWLSKHANDYDsdtykthmsryeslsnqfeqlegyqyeski 146
Cdd:cd03245 83 VPQDVTLFY-GTLRDniTLGAPLADDERILRAAELAgvTDFVNKHPNGLD------------------------------ 131
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 147 ktvlhgLNFSEEDFNkpindFSGGQKTRLSLAQMLLNEPDLLLLDEPTNHLDLETTKWLEDYLRYFKG--AIVIISHdRY 224
Cdd:cd03245 132 ------LQIGERGRG-----LSGGQRQAVALARALLNDPPILLLDEPTSAMDMNSEERLKERLRQLLGdkTLIIITH-RP 199
|
....*....
gi 446524717 225 FLDKIVTQI 233
Cdd:cd03245 200 SLLDLVDRI 208
|
|
| ABC_drug_resistance_like |
cd03264 |
ABC-type multidrug transport system, ATPase component; The biological function of this family ... |
347-478 |
1.99e-12 |
|
ABC-type multidrug transport system, ATPase component; The biological function of this family is not well characterized, but display ABC domains similar to members of ABCA subfamily. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213231 [Multi-domain] Cd Length: 211 Bit Score: 66.83 E-value: 1.99e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 347 PISIEVSKGDHiAIIGPNGIGKSTLIKTIANQQKALNGYITF-----GANLQ-----IGYYDQkqaEFKSSKTI-----L 411
Cdd:cd03264 18 GVSLTLGPGMY-GLLGPNGAGKTTLMRILATLTPPSSGTIRIdgqdvLKQPQklrrrIGYLPQ---EFGVYPNFtvrefL 93
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 412 DYVWDQYPLMN---EKDIRAVLGRfLFVQDDVKKIINDLSGGEKARLQLALLMLQRDNVLILDEPTNHLD 478
Cdd:cd03264 94 DYIAWLKGIPSkevKARVDEVLEL-VNLGDRAKKKIGSLSGGMRRRVGIAQALVGDPSILIVDEPTAGLD 162
|
|
| PRK11174 |
PRK11174 |
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed |
331-501 |
2.04e-12 |
|
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
Pssm-ID: 236870 [Multi-domain] Cd Length: 588 Bit Score: 69.87 E-value: 2.04e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 331 MHVKNLEI-GYQ-TAITKPISIEVSKGDHIAIIGPNGIGKSTLIKtianqqkALNGYITFGANLQIGYYDQKQAEFKSSK 408
Cdd:PRK11174 350 IEAEDLEIlSPDgKTLAGPLNFTLPAGQRIALVGPSGAGKTSLLN-------ALLGFLPYQGSLKINGIELRELDPESWR 422
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 409 ---------------TILDYVWDQYPLMNEKDIRAVLGRfLFVQDDVKK-------IIND----LSGGEKARLQLALLML 462
Cdd:PRK11174 423 khlswvgqnpqlphgTLRDNVLLGNPDASDEQLQQALEN-AWVSEFLPLlpqgldtPIGDqaagLSVGQAQRLALARALL 501
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 446524717 463 QRDNVLILDEPTNHLDIDSKEMLEQALQH--FEGTILFVSH 501
Cdd:PRK11174 502 QPCQLLLLDEPTASLDAHSEQLVMQALNAasRRQTTLMVTH 542
|
|
| ABC_putative_ATPase |
cd03269 |
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the ... |
331-501 |
2.08e-12 |
|
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the subfamily A transporters involved in drug resistance, nodulation, lipid transport, and bacteriocin and lantibiotic immunity. In eubacteria and archaea, the typical organization consists of one ABC and one or two integral membranes. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213236 [Multi-domain] Cd Length: 210 Bit Score: 66.54 E-value: 2.08e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 331 MHVKNL--EIGYQTAItKPISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITF-GANLQ------IGYYDQKQ 401
Cdd:cd03269 1 LEVENVtkRFGRVTAL-DDISFSVEKGEIFGLLGPNGAGKTTTIRMILGIILPDSGEVLFdGKPLDiaarnrIGYLPEER 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 402 AEFKSSKTI--LDYVWDQYPlMNEKDIRAVLGRFL---FVQDDVKKIINDLSGGEKARLQLALLMLQRDNVLILDEPTNH 476
Cdd:cd03269 80 GLYPKMKVIdqLVYLAQLKG-LKKEEARRRIDEWLerlELSEYANKRVEELSKGNQQKVQFIAAVIHDPELLILDEPFSG 158
|
170 180
....*....|....*....|....*...
gi 446524717 477 LDIDSKEMLEQALQHFEG---TILFVSH 501
Cdd:cd03269 159 LDPVNVELLKDVIRELARagkTVILSTH 186
|
|
| PRK13536 |
PRK13536 |
nodulation factor ABC transporter ATP-binding protein NodI; |
343-501 |
2.13e-12 |
|
nodulation factor ABC transporter ATP-binding protein NodI;
Pssm-ID: 237419 [Multi-domain] Cd Length: 340 Bit Score: 68.70 E-value: 2.13e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 343 AITKPISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITF----------GANLQIGY---YDQKQAEFKSSKT 409
Cdd:PRK13536 55 AVVNGLSFTVASGECFGLLGPNGAGKSTIARMILGMTSPDAGKITVlgvpvpararLARARIGVvpqFDNLDLEFTVREN 134
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 410 ILdyVWDQYPLMNEKDIRAV---LGRFLFVQDDVKKIINDLSGGEKARLQLALLMLQRDNVLILDEPTNHLDIDSKEMLE 486
Cdd:PRK13536 135 LL--VFGRYFGMSTREIEAVipsLLEFARLESKADARVSDLSGGMKRRLTLARALINDPQLLILDEPTTGLDPHARHLIW 212
|
170
....*....|....*...
gi 446524717 487 QALQHFEG---TILFVSH 501
Cdd:PRK13536 213 ERLRSLLArgkTILLTTH 230
|
|
| ABC_PotA_N |
cd03300 |
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and ... |
4-222 |
2.25e-12 |
|
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and the ATPase component of the spermidine/putrescine-preferential uptake system consisting of PotA, -B, -C, and -D. PotA has two domains with the N-terminal domain containing the ATPase activity and the residues required for homodimerization with PotA and heterdimerization with PotB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213267 [Multi-domain] Cd Length: 232 Bit Score: 66.88 E-value: 2.25e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 4 LQLNHISKSFDGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNV----SKIKNL-----KLGYLTQQ 74
Cdd:cd03300 1 IELENVSKFYGGFVALDGVSLDIKEGEFFTLLGPSGCGKTTLLRLIAGFETPTSGEIlldgKDITNLpphkrPVNTVFQN 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 75 MTLNSNATVFEEMSKPFEHIKRMESLIKEETDWLSKhandydsdtykthmsryeslsnqFEQLEGYQyeskiktvlhgln 154
Cdd:cd03300 81 YALFPHLTVFENIAFGLRLKKLPKAEIKERVAEALD-----------------------LVQLEGYA------------- 124
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446524717 155 fseedfNKPINDFSGGQKTRLSLAQMLLNEPDLLLLDEPTNHLDLETTKWLEDYLRYFKGAI----VIISHD 222
Cdd:cd03300 125 ------NRKPSQLSGGQQQRVAIARALVNEPKVLLLDEPLGALDLKLRKDMQLELKRLQKELgitfVFVTHD 190
|
|
| ABC_ModC_molybdenum_transporter |
cd03297 |
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type ... |
1-222 |
2.27e-12 |
|
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213264 [Multi-domain] Cd Length: 214 Bit Score: 66.55 E-value: 2.27e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 1 MILLQlnhISKSFDGediFT-DVDFEVKtGERIGIVGRNGAGKSTLMKIIAGVENYDSGNV----------SKIKNL--- 66
Cdd:cd03297 1 MLCVD---IEKRLPD---FTlKIDFDLN-EEVTGIFGASGAGKSTLLRCIAGLEKPDGGTIvlngtvlfdsRKKINLppq 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 67 --KLGYLTQQMTLNSNATVFEEMskpfehikrmeslikeetdwlskhandydsdTYKTHMSRYESLSNQFEQLEGYQYES 144
Cdd:cd03297 74 qrKIGLVFQQYALFPHLNVRENL-------------------------------AFGLKRKRNREDRISVDELLDLLGLD 122
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 145 KIKtvlhglnfseedfNKPINDFSGGQKTRLSLAQMLLNEPDLLLLDEPTNHLDLETTKWLEDYLR----YFKGAIVIIS 220
Cdd:cd03297 123 HLL-------------NRYPAQLSGGEKQRVALARALAAQPELLLLDEPFSALDRALRLQLLPELKqikkNLNIPVIFVT 189
|
..
gi 446524717 221 HD 222
Cdd:cd03297 190 HD 191
|
|
| DppF |
COG1124 |
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ... |
3-230 |
2.93e-12 |
|
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];
Pssm-ID: 440741 [Multi-domain] Cd Length: 248 Bit Score: 67.14 E-value: 2.93e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 3 LLQLNHISKSF----DGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNVS------KIKNLKLGYLT 72
Cdd:COG1124 1 MLEVRNLSVSYgqggRRVPVLKDVSLEVAPGESFGLVGESGSGKSTLLRALAGLERPWSGEVTfdgrpvTRRRRKAFRRR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 73 QQM-------TLNSNATVFEEMSKPFEHIKRMESlikeetdwlskhandydsdtykthmsryeslsnqfeqlegyqyESK 145
Cdd:COG1124 81 VQMvfqdpyaSLHPRHTVDRILAEPLRIHGLPDR-------------------------------------------EER 117
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 146 IKTVLHGLNFSEEDFNKPINDFSGGQKTRLSLAQMLLNEPDLLLLDEPTNHLDLETTK----WLEDYLRYFKGAIVIISH 221
Cdd:COG1124 118 IAELLEQVGLPPSFLDRYPHQLSGGQRQRVAIARALILEPELLLLDEPTSALDVSVQAeilnLLKDLREERGLTYLFVSH 197
|
250
....*....|...
gi 446524717 222 D----RYFLDKIV 230
Cdd:COG1124 198 DlavvAHLCDRVA 210
|
|
| PhnL |
COG4778 |
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion ... |
2-237 |
3.49e-12 |
|
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion transport and metabolism];
Pssm-ID: 443809 [Multi-domain] Cd Length: 229 Bit Score: 66.30 E-value: 3.49e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 2 ILLQLNHISKSF-----DGEDI--FTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGveNY--DSGNV------------ 60
Cdd:COG4778 3 TLLEVENLSKTFtlhlqGGKRLpvLDGVSFSVAAGECVALTGPSGAGKSTLLKCIYG--NYlpDSGSIlvrhdggwvdla 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 61 ----SKIKNLK---LGYLTQqmtlnsnatvfeemskpFEH-IKR-------MESLIKEETDwlskhandydsdtykthms 125
Cdd:COG4778 81 qaspREILALRrrtIGYVSQ-----------------FLRvIPRvsaldvvAEPLLERGVD------------------- 124
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 126 RYESlsnqfeqlegyqyESKIKTVLHGLNFSEEDFNKPINDFSGGQKTRLSLAQMLLNEPDLLLLDEPTNHLDLETTKWL 205
Cdd:COG4778 125 REEA-------------RARARELLARLNLPERLWDLPPATFSGGEQQRVNIARGFIADPPLLLLDEPTASLDAANRAVV 191
|
250 260 270
....*....|....*....|....*....|....*
gi 446524717 206 EDYLRYFKG---AIVIISHDRYFLDKIVTQIYDVA 237
Cdd:COG4778 192 VELIEEAKArgtAIIGIFHDEEVREAVADRVVDVT 226
|
|
| AztA |
NF040873 |
zinc ABC transporter ATP-binding protein AztA; |
12-222 |
4.17e-12 |
|
zinc ABC transporter ATP-binding protein AztA;
Pssm-ID: 468810 [Multi-domain] Cd Length: 191 Bit Score: 65.33 E-value: 4.17e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 12 SFDGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNVSKIKNLKLGYLTQQMTLNSN--ATVFE--EM 87
Cdd:NF040873 1 GYGGRPVLHGVDLTIPAGSLTAVVGPNGSGKSTLLKVLAGVLRPTSGTVRRAGGARVAYVPQRSEVPDSlpLTVRDlvAM 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 88 SKpFEHIKRMESLIKEETdwlskhandydsdtykthmsryESLSNQFEQLegyqyeskiktvlhGLnfseEDF-NKPIND 166
Cdd:NF040873 81 GR-WARRGLWRRLTRDDR----------------------AAVDDALERV--------------GL----ADLaGRQLGE 119
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 446524717 167 FSGGQKTRLSLAQMLLNEPDLLLLDEPTNHLDLETTKWLEDYLRYFKG---AIVIISHD 222
Cdd:NF040873 120 LSGGQRQRALLAQGLAQEADLLLLDEPTTGLDAESRERIIALLAEEHArgaTVVVVTHD 178
|
|
| ccmA |
TIGR01189 |
heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein ... |
342-501 |
4.41e-12 |
|
heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein encoded by ccmA in bacteria. An exception is, an arabidopsis protein. Quite likely this is encoded by an organelle. Bacterial c-type cytocromes are located on the periplasmic side of the cytoplasmic membrane. Several gene products encoded in a locus designated as 'ccm' are implicated in the transport and assembly of the functional cytochrome C. This cluster includes genes: ccmA;B;C;D;E;F;G and H. The posttranslational pathway includes the transport of heme moiety, the secretion of the apoprotein and the covalent attachment of the heme with the apoprotein. The proteins ccmA and B represent an ABC transporter; ccmC and D participate in heme transfer to ccmE, which function as a periplasmic heme chaperone. The presence of ccmF, G and H is suggested to be obligatory for the final functional assembly of cytochrome c. [Protein fate, Protein and peptide secretion and trafficking, Transport and binding proteins, Other]
Pssm-ID: 273491 [Multi-domain] Cd Length: 198 Bit Score: 65.46 E-value: 4.41e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 342 TAITKPISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITFGA---NLQIGYYDQK------QAEFKSSKTILD 412
Cdd:TIGR01189 13 RMLFEGLSFTLNAGEALQVTGPNGIGKTTLLRILAGLLRPDSGEVRWNGtplAEQRDEPHENilylghLPGLKPELSALE 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 413 --------------YVWDQYPLMNEKDIRAVLGRFLfvqddvkkiindlSGGEKARLQLALLMLQRDNVLILDEPTNHLD 478
Cdd:TIGR01189 93 nlhfwaaihggaqrTIEDALAAVGLTGFEDLPAAQL-------------SAGQQRRLALARLWLSRRPLWILDEPTTALD 159
|
170 180
....*....|....*....|....*.
gi 446524717 479 IDSKEMLEQAL-QHFE--GTILFVSH 501
Cdd:TIGR01189 160 KAGVALLAGLLrAHLArgGIVLLTTH 185
|
|
| LivG |
COG0411 |
ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid ... |
348-513 |
4.74e-12 |
|
ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid transport and metabolism];
Pssm-ID: 440180 [Multi-domain] Cd Length: 257 Bit Score: 66.60 E-value: 4.74e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 348 ISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITFG---------------------------------ANLQI 394
Cdd:COG0411 23 VSLEVERGEIVGLIGPNGAGKTTLFNLITGFYRPTSGRILFDgrditglpphriarlgiartfqnprlfpeltvlENVLV 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 395 GYYDQKQAEFKSSKTILDYVWDQYPLMNEKdIRAVLGRF-LfvQDDVKKIINDLSGGEKARLQLALLMLQRDNVLILDEP 473
Cdd:COG0411 103 AAHARLGRGLLAALLRLPRARREEREARER-AEELLERVgL--ADRADEPAGNLSYGQQRRLEIARALATEPKLLLLDEP 179
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 446524717 474 T---NHLDIDskEMLE--QALQHFEG-TILFVSHDRYFINQLANKV 513
Cdd:COG0411 180 AaglNPEETE--ELAEliRRLRDERGiTILLIEHDMDLVMGLADRI 223
|
|
| MlaF |
COG1127 |
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall ... |
333-502 |
4.97e-12 |
|
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440744 [Multi-domain] Cd Length: 241 Bit Score: 66.16 E-value: 4.97e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 333 VKNLEIGY-QTAITKPISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYIT-FGANL-------------QIGYY 397
Cdd:COG1127 8 VRNLTKSFgDRVVLDGVSLDVPRGEILAIIGGSGSGKSVLLKLIIGLLRPDSGEILvDGQDItglsekelyelrrRIGML 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 398 DQKQAEFkSSKTILDYVwdQYPL-----MNEKDIRA-VLGRFLFV--QDDVKKIINDLSGGEKARLQLA-LLMLQRDnVL 468
Cdd:COG1127 88 FQGGALF-DSLTVFENV--AFPLrehtdLSEAEIRElVLEKLELVglPGAADKMPSELSGGMRKRVALArALALDPE-IL 163
|
170 180 190
....*....|....*....|....*....|....*...
gi 446524717 469 ILDEPTNHLDIDSKEMLEQ---ALQH-FEGTILFVSHD 502
Cdd:COG1127 164 LYDEPTAGLDPITSAVIDElirELRDeLGLTSVVVTHD 201
|
|
| ABCG_EPDR |
cd03213 |
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette ... |
333-516 |
6.52e-12 |
|
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily; ABCG transporters are involved in eye pigment (EP) precursor transport, regulation of lipid-trafficking mechanisms, and pleiotropic drug resistance (DR). DR is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. Compared to other members of the ABC transporter subfamilies, the ABCG transporter family is composed of proteins that have an ATP-binding cassette domain at the N-terminus and a TM (transmembrane) domain at the C-terminus.
Pssm-ID: 213180 [Multi-domain] Cd Length: 194 Bit Score: 64.88 E-value: 6.52e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 333 VKNLEIGYQTAITKPISIEVSKGDHIAIIGPNGIGKSTLIKTIANQqkaLNGYITFGanlQIgYYDQKQAEFKSSKTILD 412
Cdd:cd03213 13 VKSSPSKSGKQLLKNVSGKAKPGELTAIMGPSGAGKSTLLNALAGR---RTGLGVSG---EV-LINGRPLDKRSFRKIIG 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 413 YVwDQyplmneKDIraVLGrFLFVQD--DVKKIINDLSGGEKARLQLALLMLQRDNVLILDEPTNHLDIDSKEMLEQALQ 490
Cdd:cd03213 86 YV-PQ------DDI--LHP-TLTVREtlMFAAKLRGLSGGERKRVSIALELVSNPSLLFLDEPTSGLDSSSALQVMSLLR 155
|
170 180
....*....|....*....|....*....
gi 446524717 491 HF--EG-TILFVSHdryfinQLANKVFDL 516
Cdd:cd03213 156 RLadTGrTIICSIH------QPSSEIFEL 178
|
|
| ABC_Mj1267_LivG_branched |
cd03219 |
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ... |
4-60 |
8.01e-12 |
|
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ABC transporter subfamily is involved in the transport of the hydrophobic amino acids leucine, isoleucine and valine. MJ1267 is a branched-chain amino acid transporter with 29% similarity to both the LivF and LivG components of the E. coli branched-chain amino acid transporter. MJ1267 contains an insertion from residues 114 to 123 characteristic of LivG (Leucine-Isoleucine-Valine) homologs. The branched-chain amino acid transporter from E. coli comprises a heterodimer of ABCs (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ).
Pssm-ID: 213186 [Multi-domain] Cd Length: 236 Bit Score: 65.54 E-value: 8.01e-12
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*..
gi 446524717 4 LQLNHISKSFDGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNV 60
Cdd:cd03219 1 LEVRGLTKRFGGLVALDDVSFSVRPGEIHGLIGPNGAGKTTLFNLISGFLRPTSGSV 57
|
|
| ABC_HisP_GlnQ |
cd03262 |
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ... |
4-203 |
8.55e-12 |
|
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ATP-binding components of the bacterial periplasmic histidine and glutamine permeases, respectively. Histidine permease is a multi-subunit complex containing the HisQ and HisM integral membrane subunits and two copies of HisP. HisP has properties intermediate between those of integral and peripheral membrane proteins and is accessible from both sides of the membrane, presumably by its interaction with HisQ and HisM. The two HisP subunits form a homodimer within the complex. The domain structure of the amino acid uptake systems is typical for prokaryotic extracellular solute binding protein-dependent uptake systems. All of the amino acid uptake systems also have at least one, and in a few cases, two extracellular solute binding proteins located in the periplasm of Gram-negative bacteria, or attached to the cell membrane of Gram-positive bacteria. The best-studied member of the PAAT (polar amino acid transport) family is the HisJQMP system of S. typhimurium, where HisJ is the extracellular solute binding proteins and HisP is the ABC protein.
Pssm-ID: 213229 [Multi-domain] Cd Length: 213 Bit Score: 64.86 E-value: 8.55e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 4 LQLNHISKSFDGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNVS-----------KIKNL--KLGY 70
Cdd:cd03262 1 IEIKNLHKSFGDFHVLKGIDLTVKKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTIIidglkltddkkNINELrqKVGM 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 71 LTQQMTLNSNATVFEEMskpfehikrMESLIKEEtdwlskhandydsdtyktHMSRYESLSNQFEQLEGYQYESKIktvl 150
Cdd:cd03262 81 VFQQFNLFPHLTVLENI---------TLAPIKVK------------------GMSKAEAEERALELLEKVGLADKA---- 129
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 446524717 151 hglnfseedfNKPINDFSGGQKTRLSLAQMLLNEPDLLLLDEPTNHLDLETTK 203
Cdd:cd03262 130 ----------DAYPAQLSGGQQQRVAIARALAMNPKVMLFDEPTSALDPELVG 172
|
|
| FtsE |
COG2884 |
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning]; |
1-75 |
1.00e-11 |
|
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442130 [Multi-domain] Cd Length: 223 Bit Score: 65.07 E-value: 1.00e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 1 MIllQLNHISKSF-DGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSG-------NVSKIKNLKLGYLT 72
Cdd:COG2884 1 MI--RFENVSKRYpGGREALSDVSLEIEKGEFVFLTGPSGAGKSTLLKLLYGEERPTSGqvlvngqDLSRLKRREIPYLR 78
|
...
gi 446524717 73 QQM 75
Cdd:COG2884 79 RRI 81
|
|
| PotA |
COG3842 |
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport ... |
1-60 |
1.02e-11 |
|
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443052 [Multi-domain] Cd Length: 353 Bit Score: 66.66 E-value: 1.02e-11
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 1 MILLQLNHISKSFDGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNV 60
Cdd:COG3842 3 MPALELENVSKRYGDVTALDDVSLSIEPGEFVALLGPSGCGKTTLLRMIAGFETPDSGRI 62
|
|
| xylG |
TIGR02633 |
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ... |
3-221 |
1.28e-11 |
|
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]
Pssm-ID: 131681 [Multi-domain] Cd Length: 500 Bit Score: 67.16 E-value: 1.28e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 3 LLQLNHISKSFDGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGV--------ENYDSGNVSKIKNLK------L 68
Cdd:TIGR02633 1 LLEMKGIVKTFGGVKALDGIDLEVRPGECVGLCGENGAGKSTLMKILSGVyphgtwdgEIYWSGSPLKASNIRdteragI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 69 GYLTQQMTLNSNATVFEEMskpfehikrmesLIKEETdwlskhandydsdTYKTHMSRYESLSNQFEQLegyqyeskikt 148
Cdd:TIGR02633 81 VIIHQELTLVPELSVAENI------------FLGNEI-------------TLPGGRMAYNAMYLRAKNL----------- 124
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446524717 149 vLHGLNFSEEDFNKPINDFSGGQKTRLSLAQMLLNEPDLLLLDEPTNHLDLETTKWLEDYLRYFKG---AIVIISH 221
Cdd:TIGR02633 125 -LRELQLDADNVTRPVGDYGGGQQQLVEIAKALNKQARLLILDEPSSSLTEKETEILLDIIRDLKAhgvACVYISH 199
|
|
| ABC_MalK_N |
cd03301 |
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) ... |
4-110 |
1.89e-11 |
|
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) proteins function from bacteria to human, mediating the translocation of substances into and out of cells or organelles. ABC transporters contain two transmembrane-spanning domains (TMDs) or subunits and two nucleotide binding domains (NBDs) or subunits that couple transport to the hydrolysis of ATP. In the maltose transport system, the periplasmic maltose binding protein (MBP) stimulates the ATPase activity of the membrane-associated transporter, which consists of two transmembrane subunits, MalF and MalG, and two copies of the ATP binding subunit, MalK, and becomes tightly bound to the transporter in the catalytic transition state, ensuring that maltose is passed to the transporter as ATP is hydrolyzed.
Pssm-ID: 213268 [Multi-domain] Cd Length: 213 Bit Score: 63.81 E-value: 1.89e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 4 LQLNHISKSFDGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNVS---------KIKNLKLGYLTQQ 74
Cdd:cd03301 1 VELENVTKRFGNVTALDDLNLDIADGEFVVLLGPSGCGKTTTLRMIAGLEEPTSGRIYiggrdvtdlPPKDRDIAMVFQN 80
|
90 100 110
....*....|....*....|....*....|....*.
gi 446524717 75 MTLNSNATVFEEMSKPFEHIKRMESLIKEETDWLSK 110
Cdd:cd03301 81 YALYPHMTVYDNIAFGLKLRKVPKDEIDERVREVAE 116
|
|
| ABC_DrrA |
cd03265 |
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein ... |
333-523 |
2.13e-11 |
|
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein component of a bacterial exporter complex that confers resistance to the antibiotics daunorubicin and doxorubicin. In addition to DrrA, the complex includes an integral membrane protein called DrrB. DrrA belongs to the ABC family of transporters and shares sequence and functional similarities with a protein found in cancer cells called P-glycoprotein. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213232 [Multi-domain] Cd Length: 220 Bit Score: 63.93 E-value: 2.13e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 333 VKNLEIGY-QTAITKPISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGY-ITFGANL---------QIGYYDQkQ 401
Cdd:cd03265 3 VENLVKKYgDFEAVRGVSFRVRRGEIFGLLGPNGAGKTTTIKMLTTLLKPTSGRaTVAGHDVvreprevrrRIGIVFQ-D 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 402 AEFKSSKTILDYVWDQ---YPLMNEK---DIRAVLgRFLFVQDDVKKIINDLSGGEKARLQLALLMLQRDNVLILDEPTN 475
Cdd:cd03265 82 LSVDDELTGWENLYIHarlYGVPGAErreRIDELL-DFVGLLEAADRLVKTYSGGMRRRLEIARSLVHRPEVLFLDEPTI 160
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 446524717 476 HLDIDSK----EMLEQALQHFEGTILFVSHDRYFINQLANKVfdLTIDGGKM 523
Cdd:cd03265 161 GLDPQTRahvwEYIEKLKEEFGMTILLTTHYMEEAEQLCDRV--AIIDHGRI 210
|
|
| 3a01203 |
TIGR00954 |
Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, ... |
348-501 |
2.22e-11 |
|
Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]
Pssm-ID: 273360 [Multi-domain] Cd Length: 659 Bit Score: 66.70 E-value: 2.22e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 348 ISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITFGANLQIGYYDQKqaEFKSSKTILDYVWdqYPL------- 420
Cdd:TIGR00954 471 LSFEVPSGNNLLICGPNGCGKSSLFRILGELWPVYGGRLTKPAKGKLFYVPQR--PYMTLGTLRDQII--YPDssedmkr 546
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 421 --MNEKDIRAVL------------GRFLFVQD--DVkkiindLSGGEKARLQLALLMLQRDNVLILDEPTNHLDIDSKEM 484
Cdd:TIGR00954 547 rgLSDKDLEQILdnvqlthilereGGWSAVQDwmDV------LSGGEKQRIAMARLFYHKPQFAILDECTSAVSVDVEGY 620
|
170
....*....|....*..
gi 446524717 485 LEQALQHFEGTILFVSH 501
Cdd:TIGR00954 621 MYRLCREFGITLFSVSH 637
|
|
| CydD |
COG4988 |
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease ... |
4-254 |
2.44e-11 |
|
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444012 [Multi-domain] Cd Length: 563 Bit Score: 66.71 E-value: 2.44e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 4 LQLNHISKSFDGED-IFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNVS----KIKNLKLGYLTQQMT-L 77
Cdd:COG4988 337 IELEDVSFSYPGGRpALDGLSLTIPPGERVALVGPSGAGKSTLLNLLLGFLPPYSGSILingvDLSDLDPASWRRQIAwV 416
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 78 NSNATVFEEmskpfehikrmeSLIkeetDWLSKHANDYDSDtykthmsryeslsnQFEQ-LEgyqyESKIKTVLHGLnfs 156
Cdd:COG4988 417 PQNPYLFAG------------TIR----ENLRLGRPDASDE--------------ELEAaLE----AAGLDEFVAAL--- 459
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 157 EEDFNKPIND----FSGGQKTRLSLAQMLLNEPDLLLLDEPTNHLDLETTKWLEDYLR-YFKGAIVI-ISHDRYFLdKIV 230
Cdd:COG4988 460 PDGLDTPLGEggrgLSGGQAQRLALARALLRDAPLLLLDEPTAHLDAETEAEILQALRrLAKGRTVIlITHRLALL-AQA 538
|
250 260
....*....|....*....|....
gi 446524717 231 TQIYDVALGDVKRyVGNYEEFIQQ 254
Cdd:COG4988 539 DRILVLDDGRIVE-QGTHEELLAK 561
|
|
| PRK10575 |
PRK10575 |
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC; |
347-510 |
2.68e-11 |
|
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;
Pssm-ID: 182561 [Multi-domain] Cd Length: 265 Bit Score: 64.42 E-value: 2.68e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 347 PISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITFganlqigyyDQKQAEFKSSKTI---LDYVWDQYPL--- 420
Cdd:PRK10575 29 PLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILL---------DAQPLESWSSKAFarkVAYLPQQLPAaeg 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 421 MNEKDIRAV--------LGRFlFVQDDVK---------------KIINDLSGGEKARLQLALLMLQRDNVLILDEPTNHL 477
Cdd:PRK10575 100 MTVRELVAIgrypwhgaLGRF-GAADREKveeaislvglkplahRLVDSLSGGERQRAWIAMLVAQDSRCLLLDEPTSAL 178
|
170 180 190
....*....|....*....|....*....|....*..
gi 446524717 478 DIDSK-EMLE--QALQHFEG-TILFVSHDryfINQLA 510
Cdd:PRK10575 179 DIAHQvDVLAlvHRLSQERGlTVIAVLHD---INMAA 212
|
|
| PRK14258 |
PRK14258 |
phosphate ABC transporter ATP-binding protein; Provisional |
331-511 |
2.70e-11 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 184593 [Multi-domain] Cd Length: 261 Bit Score: 64.29 E-value: 2.70e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 331 MHVKNLEIGYQT-AITKPISIEVSKGDHIAIIGPNGIGKSTLIKTIaNQQKALNGYIT-------FGANL---------- 392
Cdd:PRK14258 8 IKVNNLSFYYDTqKILEGVSMEIYQSKVTAIIGPSGCGKSTFLKCL-NRMNELESEVRvegrvefFNQNIyerrvnlnrl 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 393 --QIGYYDQKQAEFKSSktILDYV--------WdqYPLMNEKDIRAVLGRFLFVQDDVKKIIN----DLSGGEKARLQLA 458
Cdd:PRK14258 87 rrQVSMVHPKPNLFPMS--VYDNVaygvkivgW--RPKLEIDDIVESALKDADLWDEIKHKIHksalDLSGGQQQRLCIA 162
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 446524717 459 LLMLQRDNVLILDEPTNHLDIDSKEMLEQALQHF----EGTILFVSHDRYFINQLAN 511
Cdd:PRK14258 163 RALAVKPKVLLMDEPCFGLDPIASMKVESLIQSLrlrsELTMVIVSHNLHQVSRLSD 219
|
|
| modC_ABC |
TIGR02142 |
molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding ... |
348-523 |
2.76e-11 |
|
molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding cassette (ABC) protein of the three subunit molybdate ABC transporter. The three proteins of this complex are homologous to proteins of the sulfate ABC transporter. Molybdenum may be used in nitrogenases of nitrogen-fixing bacteria and in molybdopterin cofactors. In some cases, molybdate may be transported by a sulfate transporter rather than by a specific molybdate transporter. [Transport and binding proteins, Anions]
Pssm-ID: 131197 [Multi-domain] Cd Length: 354 Bit Score: 65.52 E-value: 2.76e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 348 ISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITF-GANLQ--------------IGYYDQKQAEFK--SSKTI 410
Cdd:TIGR02142 16 ADFTLPGQGVTAIFGRSGSGKTTLIRLIAGLTRPDEGEIVLnGRTLFdsrkgiflppekrrIGYVFQEARLFPhlSVRGN 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 411 LDY-VWD---QYPLMNEKDIRAVLGrflfVQDDVKKIINDLSGGEKARLQLALLMLQRDNVLILDEPTNHLDIDSKE--- 483
Cdd:TIGR02142 96 LRYgMKRarpSERRISFERVIELLG----IGHLLGRLPGRLSGGEKQRVAIGRALLSSPRLLLMDEPLAALDDPRKYeil 171
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 446524717 484 -MLEQALQHFEGTILFVSHDRYFINQLANKVfdLTIDGGKM 523
Cdd:TIGR02142 172 pYLERLHAEFGIPILYVSHSLQEVLRLADRV--VVLEDGRV 210
|
|
| hmuV |
PRK13548 |
hemin importer ATP-binding subunit; Provisional |
330-479 |
2.82e-11 |
|
hemin importer ATP-binding subunit; Provisional
Pssm-ID: 237422 [Multi-domain] Cd Length: 258 Bit Score: 64.41 E-value: 2.82e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 330 VMHVKNL--EIGyQTAITKPISIEVSKGDHIAIIGPNGIGKSTLIKtianqqkALNGYITFGANlQIGYYDQKQAEFKSS 407
Cdd:PRK13548 2 MLEARNLsvRLG-GRTLLDDVSLTLRPGEVVAILGPNGAGKSTLLR-------ALSGELSPDSG-EVRLNGRPLADWSPA 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 408 KTILdyvwdqyplmnekdIRAVL------------------GR--FLFVQDDVKKIIND-----------------LSGG 450
Cdd:PRK13548 73 ELAR--------------RRAVLpqhsslsfpftveevvamGRapHGLSRAEDDALVAAalaqvdlahlagrdypqLSGG 138
|
170 180 190
....*....|....*....|....*....|....*
gi 446524717 451 EKARLQLA--LLMLQRDN----VLILDEPTNHLDI 479
Cdd:PRK13548 139 EQQRVQLArvLAQLWEPDgpprWLLLDEPTSALDL 173
|
|
| ABC_FtsE |
cd03292 |
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where ... |
21-227 |
2.96e-11 |
|
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages
Pssm-ID: 213259 [Multi-domain] Cd Length: 214 Bit Score: 63.58 E-value: 2.96e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 21 DVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSG-------NVSKIKNLKLGYLTQQM-------TLNSNATVFEE 86
Cdd:cd03292 19 GINISISAGEFVFLVGPSGAGKSTLLKLIYKEELPTSGtirvngqDVSDLRGRAIPYLRRKIgvvfqdfRLLPDRNVYEN 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 87 MSKPFEHIKRMESLIKEetdwlskhandydsdtykthmsryeslsnqfeqlegyqyesKIKTVLHGLNFSEEDFNKPiND 166
Cdd:cd03292 99 VAFALEVTGVPPREIRK-----------------------------------------RVPAALELVGLSHKHRALP-AE 136
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446524717 167 FSGGQKTRLSLAQMLLNEPDLLLLDEPTNHLDLETTKWLEDYLRYFKGA---IVIISHDRYFLD 227
Cdd:cd03292 137 LSGGEQQRVAIARAIVNSPTILIADEPTGNLDPDTTWEIMNLLKKINKAgttVVVATHAKELVD 200
|
|
| ABCC_TAP |
cd03248 |
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; ... |
342-523 |
2.98e-11 |
|
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; TAP (Transporter Associated with Antigen Processing) is essential for peptide delivery from the cytosol into the lumen of the endoplasmic reticulum (ER), where these peptides are loaded on major histocompatibility complex (MHC) I molecules. Loaded MHC I leave the ER and display their antigenic cargo on the cell surface to cytotoxic T cells. Subsequently, virus-infected or malignantly transformed cells can be eliminated. TAP belongs to the large family of ATP-binding cassette (ABC) transporters, which translocate a vast variety of solutes across membranes.
Pssm-ID: 213215 [Multi-domain] Cd Length: 226 Bit Score: 63.64 E-value: 2.98e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 342 TAITKPISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITFGANlQIGYYDQK----------QAEFKSSKTIL 411
Cdd:cd03248 27 TLVLQDVSFTLHPGEVTALVGPSGSGKSTVVALLENFYQPQGGQVLLDGK-PISQYEHKylhskvslvgQEPVLFARSLQ 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 412 D---YVWDQYPLMNEKDIRAVLGRFLFVQD-------DVKKIINDLSGGEKARLQLALLMLQRDNVLILDEPTNHLDIDS 481
Cdd:cd03248 106 DniaYGLQSCSFECVKEAAQKAHAHSFISElasgydtEVGEKGSQLSGGQKQRVAIARALIRNPQVLILDEATSALDAES 185
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 446524717 482 KEMLEQALQ--HFEGTILFVSHdRYFINQLANKVfdLTIDGGKM 523
Cdd:cd03248 186 EQQVQQALYdwPERRTVLVIAH-RLSTVERADQI--LVLDGGRI 226
|
|
| PRK13549 |
PRK13549 |
xylose transporter ATP-binding subunit; Provisional |
3-87 |
3.04e-11 |
|
xylose transporter ATP-binding subunit; Provisional
Pssm-ID: 184134 [Multi-domain] Cd Length: 506 Bit Score: 66.11 E-value: 3.04e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 3 LLQLNHISKSFDGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGV--------ENYDSGNVSKIKNLK------L 68
Cdd:PRK13549 5 LLEMKNITKTFGGVKALDNVSLKVRAGEIVSLCGENGAGKSTLMKVLSGVyphgtyegEIIFEGEELQASNIRdteragI 84
|
90
....*....|....*....
gi 446524717 69 GYLTQQMTLNSNATVFEEM 87
Cdd:PRK13549 85 AIIHQELALVKELSVLENI 103
|
|
| YhaQ |
COG4152 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
348-502 |
3.89e-11 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 443322 [Multi-domain] Cd Length: 298 Bit Score: 64.36 E-value: 3.89e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 348 ISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITF-GANL------QIGY-------YdqkqaefKSSKtildy 413
Cdd:COG4152 20 VSFTVPKGEIFGLLGPNGAGKTTTIRIILGILAPDSGEVLWdGEPLdpedrrRIGYlpeerglY-------PKMK----- 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 414 VWDQ--YpL-----MNEKDIRAVLGRFL--F-VQDDVKKIINDLSGGEKARLQLALLMLQRDNVLILDEPTNHLDIDSKE 483
Cdd:COG4152 88 VGEQlvY-LarlkgLSKAEAKRRADEWLerLgLGDRANKKVEELSKGNQQKVQLIAALLHDPELLILDEPFSGLDPVNVE 166
|
170 180
....*....|....*....|..
gi 446524717 484 MLEQALQHF--EG-TILFVSHD 502
Cdd:COG4152 167 LLKDVIRELaaKGtTVIFSSHQ 188
|
|
| ABC_YhbG |
cd03218 |
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the ... |
4-103 |
5.67e-11 |
|
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the YhbG family are similar to members of the Mj1267_LivG family, which is involved in the transport of branched-chain amino acids. The genes yhbG and yhbN are located in a single operon and may function together in cell envelope during biogenesis. YhbG is the putative ATP-binding cassette component and YhbN is the putative periplasmic-binding protein. Depletion of each gene product leads to growth arrest, irreversible cell damage and loss of viability in E. coli. The YhbG homolog (NtrA) is essential in Rhizobium meliloti, a symbiotic nitrogen-fixing bacterium.
Pssm-ID: 213185 [Multi-domain] Cd Length: 232 Bit Score: 62.95 E-value: 5.67e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 4 LQLNHISKSFDGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNV------------SKIKNLKLGYL 71
Cdd:cd03218 1 LRAENLSKRYGKRKVVNGVSLSVKQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGKIlldgqditklpmHKRARLGIGYL 80
|
90 100 110 120
....*....|....*....|....*....|....*....|
gi 446524717 72 TQQMTLNSNATV-------FEEMSKPF-EHIKRMESLIKE 103
Cdd:cd03218 81 PQEASIFRKLTVeenilavLEIRGLSKkEREEKLEELLEE 120
|
|
| PLN03073 |
PLN03073 |
ABC transporter F family; Provisional |
428-567 |
5.70e-11 |
|
ABC transporter F family; Provisional
Pssm-ID: 215558 [Multi-domain] Cd Length: 718 Bit Score: 65.65 E-value: 5.70e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 428 AVLGRFLFVQDDVKKIINDLSGGEKARLQLALLMLQRDNVLILDEPTNHLDIDSKEMLEQALQHFEGTILFVSHDRYFIN 507
Cdd:PLN03073 326 SILAGLSFTPEMQVKATKTFSGGWRMRIALARALFIEPDLLLLDEPTNHLDLHAVLWLETYLLKWPKTFIVVSHAREFLN 405
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446524717 508 QLANKVfdLTIDGGKM--YLGDYQYYiEKVEEaEALKAHQeeqsvnvQAHEkSMEQSSYHNQ 567
Cdd:PLN03073 406 TVVTDI--LHLHGQKLvtYKGDYDTF-ERTRE-EQLKNQQ-------KAFE-SNERSRSHMQ 455
|
|
| PRK10851 |
PRK10851 |
sulfate/thiosulfate ABC transporter ATP-binding protein CysA; |
342-513 |
5.79e-11 |
|
sulfate/thiosulfate ABC transporter ATP-binding protein CysA;
Pssm-ID: 182778 [Multi-domain] Cd Length: 353 Bit Score: 64.33 E-value: 5.79e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 342 TAITKPISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITFGA---------NLQIGYYDQKQAEFKsSKTILD 412
Cdd:PRK10851 15 TQVLNDISLDIPSGQMVALLGPSGSGKTTLLRIIAGLEHQTSGHIRFHGtdvsrlharDRKVGFVFQHYALFR-HMTVFD 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 413 YVW--------DQYPlmNEKDIRAVLGRFL-FVQDD--VKKIINDLSGGEKARLQLALLMLQRDNVLILDEPTNHLDID- 480
Cdd:PRK10851 94 NIAfgltvlprRERP--NAAAIKAKVTQLLeMVQLAhlADRYPAQLSGGQKQRVALARALAVEPQILLLDEPFGALDAQv 171
|
170 180 190
....*....|....*....|....*....|....*.
gi 446524717 481 SKEM---LEQALQHFEGTILFVSHDRYFINQLANKV 513
Cdd:PRK10851 172 RKELrrwLRQLHEELKFTSVFVTHDQEEAMEVADRV 207
|
|
| cbiO |
PRK13637 |
energy-coupling factor transporter ATPase; |
332-514 |
6.24e-11 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237455 [Multi-domain] Cd Length: 287 Bit Score: 63.53 E-value: 6.24e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 332 HVKNLEIGYQTAITKPISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITF-GANLQigyydQKQAEFKSSKTI 410
Cdd:PRK13637 10 HIYMEGTPFEKKALDNVNIEIEDGEFVGLIGHTGSGKSTLIQHLNGLLKPTSGKIIIdGVDIT-----DKKVKLSDIRKK 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 411 LDYVWdQYP---LMNE---KDIrAVLGRFLFVQDD-----VKKIIN---------------DLSGGEKARLQLALLMLQR 464
Cdd:PRK13637 85 VGLVF-QYPeyqLFEEtieKDI-AFGPINLGLSEEeienrVKRAMNivgldyedykdkspfELSGGQKRRVAIAGVVAME 162
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 446524717 465 DNVLILDEPTNHLDIDSK-EMLEQAL---QHFEGTILFVSHDRYFINQLANKVF 514
Cdd:PRK13637 163 PKILILDEPTAGLDPKGRdEILNKIKelhKEYNMTIILVSHSMEDVAKLADRII 216
|
|
| CeuD |
COG4604 |
ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and ... |
1-85 |
6.28e-11 |
|
ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443654 [Multi-domain] Cd Length: 252 Bit Score: 63.18 E-value: 6.28e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 1 MIllQLNHISKSFDGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNVS---------KIKNL--KLG 69
Cdd:COG4604 1 MI--EIKNVSKRYGGKVVLDDVSLTIPKGGITALIGPNGAGKSTLLSMISRLLPPDSGEVLvdgldvattPSRELakRLA 78
|
90
....*....|....*.
gi 446524717 70 YLTQQMTLNSNATVFE 85
Cdd:COG4604 79 ILRQENHINSRLTVRE 94
|
|
| TagH |
COG1134 |
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate ... |
348-549 |
6.47e-11 |
|
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440749 [Multi-domain] Cd Length: 245 Bit Score: 62.79 E-value: 6.47e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 348 ISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKA------LNGYIT----FGANLQ-----------IGyydqkqaefks 406
Cdd:COG1134 45 VSFEVERGESVGIIGRNGAGKSTLLKLIAGILEPtsgrveVNGRVSalleLGAGFHpeltgreniylNG----------- 113
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 407 skTILDyvwdqyplMNEKDIRAV---------LGRFLfvqdDVKkiINDLSGGEKARLQLALLMLQRDNVLILDEPTNHL 477
Cdd:COG1134 114 --RLLG--------LSRKEIDEKfdeivefaeLGDFI----DQP--VKTYSSGMRARLAFAVATAVDPDILLVDEVLAVG 177
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446524717 478 DIDSKEMLEQALQHF---EGTILFVSHDRYFINQLANKVfdLTIDGGKMylgdyqYYIEKVEeaEALKAHQEEQS 549
Cdd:COG1134 178 DAAFQKKCLARIRELresGRTVIFVSHSMGAVRRLCDRA--IWLEKGRL------VMDGDPE--EVIAAYEALLA 242
|
|
| ABC_KpsT_Wzt |
cd03220 |
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC ... |
334-524 |
7.17e-11 |
|
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC transporter subfamily is involved in extracellular polysaccharide export. Among the variety of membrane-linked or extracellular polysaccharides excreted by bacteria, only capsular polysaccharides, lipopolysaccharides, and teichoic acids have been shown to be exported by ABC transporters. A typical system is made of a conserved integral membrane and an ABC. In addition to these proteins, capsular polysaccharide exporter systems require two 'accessory' proteins to perform their function: a periplasmic (E.coli) or a lipid-anchored outer membrane protein called OMA (Neisseria meningitidis and Haemophilus influenza) and a cytoplasmic membrane protein MPA2.
Pssm-ID: 213187 [Multi-domain] Cd Length: 224 Bit Score: 62.55 E-value: 7.17e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 334 KNLEIGYQTAITKpISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYIT----------FGANLQ---------- 393
Cdd:cd03220 28 RKGEVGEFWALKD-VSFEVPRGERIGLIGRNGAGKSTLLRLLAGIYPPDSGTVTvrgrvssllgLGGGFNpeltgreniy 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 394 -IG-YYDQKQAEFKSsktILDYVWDqyplMNEkdiravLGRFLfvQDDVKKiindLSGGEKARLQLALLMLQRDNVLILD 471
Cdd:cd03220 107 lNGrLLGLSRKEIDE---KIDEIIE----FSE------LGDFI--DLPVKT----YSSGMKARLAFAIATALEPDILLID 167
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 446524717 472 EPTNHLDIDSKEMLEQALQHF---EGTILFVSHDRYFINQLANKVfdLTIDGGKMY 524
Cdd:cd03220 168 EVLAVGDAAFQEKCQRRLRELlkqGKTVILVSHDPSSIKRLCDRA--LVLEKGKIR 221
|
|
| hmuV |
PRK13548 |
hemin importer ATP-binding subunit; Provisional |
2-61 |
7.20e-11 |
|
hemin importer ATP-binding subunit; Provisional
Pssm-ID: 237422 [Multi-domain] Cd Length: 258 Bit Score: 62.87 E-value: 7.20e-11
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 2 ILLQLNHISKSFDGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNVS 61
Cdd:PRK13548 1 AMLEARNLSVRLGGRTLLDDVSLTLRPGEVVAILGPNGAGKSTLLRALSGELSPDSGEVR 60
|
|
| ABC_TM1139_LivF_branched |
cd03224 |
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of ... |
4-61 |
7.24e-11 |
|
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of the LIV-I bacterial ABC-type two-component transport system that imports neutral, branched-chain amino acids. The E. coli branched-chain amino acid transporter comprises a heterodimer of ABC transporters (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules.
Pssm-ID: 213191 [Multi-domain] Cd Length: 222 Bit Score: 62.45 E-value: 7.24e-11
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 446524717 4 LQLNHISKSFDGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNVS 61
Cdd:cd03224 1 LEVENLNAGYGKSQILFGVSLTVPEGEIVALLGRNGAGKTTLLKTIMGLLPPRSGSIR 58
|
|
| SufC |
COG0396 |
Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, ... |
4-230 |
7.44e-11 |
|
Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440165 [Multi-domain] Cd Length: 245 Bit Score: 62.78 E-value: 7.44e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 4 LQLNHISKSFDGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENY--DSGNVS----KIKNLK--------LG 69
Cdd:COG0396 1 LEIKNLHVSVEGKEILKGVNLTIKPGEVHAIMGPNGSGKSTLAKVLMGHPKYevTSGSILldgeDILELSpderaragIF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 70 YLTQQmtlnsnatvfeemskPFEhIK--RMESLIKEETDwlskhandydsdtykthmsryeslSNQFEQLEGYQYESKIK 147
Cdd:COG0396 81 LAFQY---------------PVE-IPgvSVSNFLRTALN------------------------ARRGEELSAREFLKLLK 120
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 148 TVLHGLNFSEEDFNKPIND-FSGGQKTRLSLAQMLLNEPDLLLLDEPTNHLDLETTKWLEDYLRYFKG---AIVIISHDR 223
Cdd:COG0396 121 EKMKELGLDEDFLDRYVNEgFSGGEKKRNEILQMLLLEPKLAILDETDSGLDIDALRIVAEGVNKLRSpdrGILIITHYQ 200
|
....*..
gi 446524717 224 YFLDKIV 230
Cdd:COG0396 201 RILDYIK 207
|
|
| F420-0_ABC_ATP |
TIGR03873 |
proposed F420-0 ABC transporter, ATP-binding protein; This small clade of ABC-type transporter ... |
359-523 |
8.94e-11 |
|
proposed F420-0 ABC transporter, ATP-binding protein; This small clade of ABC-type transporter ATP-binding protein components is found as a three gene cassette along with a periplasmic substrate-binding protein (TIGR03868) and a permease (TIGR03869). The organisms containing this cassette are all Actinobacteria and all contain numerous genes requiring the coenzyme F420. This model was defined based on five such organisms, four of which are lacking all F420 biosynthetic capability save the final side-chain polyglutamate attachment step (via the gene cofE: TIGR01916). In Jonesia denitrificans DSM 20603 and marine actinobacterium PHSC20C1 this cassette is in an apparent operon with the cofE gene and, in PHSC20C1, also with a F420-dependent glucose-6-phosphate dehydrogenase (TIGR03554). Based on these observations we propose that this ATP-binding protein is a component of an F420-0 (that is, F420 lacking only the polyglutamate tail) transporter.
Pssm-ID: 163585 [Multi-domain] Cd Length: 256 Bit Score: 62.91 E-value: 8.94e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 359 AIIGPNGIGKSTLIKTIANQQKALNGYITF-GANL----------QIGYYDQkQAEFKSSKTILDYV----------WDQ 417
Cdd:TIGR03873 31 GLLGPNGSGKSTLLRLLAGALRPDAGTVDLaGVDLhglsrrararRVALVEQ-DSDTAVPLTVRDVValgriphrslWAG 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 418 YPLMNEKDIRAVLGRfLFVQDDVKKIINDLSGGEKARLQLALLMLQRDNVLILDEPTNHLDIDSKEMLEQALQHFEG--- 494
Cdd:TIGR03873 110 DSPHDAAVVDRALAR-TELSHLADRDMSTLSGGERQRVHVARALAQEPKLLLLDEPTNHLDVRAQLETLALVRELAAtgv 188
|
170 180 190
....*....|....*....|....*....|.
gi 446524717 495 TILFVSHDRyfinQLANKVFD--LTIDGGKM 523
Cdd:TIGR03873 189 TVVAALHDL----NLAASYCDhvVVLDGGRV 215
|
|
| ABC_RNaseL_inhibitor |
cd03222 |
ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a ... |
351-513 |
1.05e-10 |
|
ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins, and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains, which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.
Pssm-ID: 213189 [Multi-domain] Cd Length: 177 Bit Score: 61.05 E-value: 1.05e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 351 EVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITfganlqigyydqkqaefkssktildyvWDQyplmnekdiravl 430
Cdd:cd03222 21 VVKEGEVIGIVGPNGTGKTTAVKILAGQLIPNGDNDE---------------------------WDG------------- 60
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 431 grflfVQDDVKKIINDLSGGEKARLQLALLMLQRDNVLILDEPTNHLDIDSKEMLEQALQHF----EGTILFVSHDRYFI 506
Cdd:cd03222 61 -----ITPVYKPQYIDLSGGELQRVAIAAALLRNATFYLFDEPSAYLDIEQRLNAARAIRRLseegKKTALVVEHDLAVL 135
|
....*..
gi 446524717 507 NQLANKV 513
Cdd:cd03222 136 DYLSDRI 142
|
|
| ABC_NatA_sodium_exporter |
cd03266 |
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a ... |
348-501 |
1.05e-10 |
|
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of a single ATP-binding protein and a single integral membrane protein.
Pssm-ID: 213233 [Multi-domain] Cd Length: 218 Bit Score: 62.00 E-value: 1.05e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 348 ISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYIT----------FGANLQIGYYDQKQAEFK--SSKTILDYVW 415
Cdd:cd03266 24 VSFTVKPGEVTGLLGPNGAGKTTTLRMLAGLLEPDAGFATvdgfdvvkepAEARRRLGFVSDSTGLYDrlTARENLEYFA 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 416 DQYPLMNekdiRAVLGRF--LFVQDDVKKIIN----DLSGGEKARLQLALLMLQRDNVLILDEPTNHLDIDSKEMLEQAL 489
Cdd:cd03266 104 GLYGLKG----DELTARLeeLADRLGMEELLDrrvgGFSTGMRQKVAIARALVHDPPVLLLDEPTTGLDVMATRALREFI 179
|
170
....*....|....*
gi 446524717 490 QHF--EG-TILFVSH 501
Cdd:cd03266 180 RQLraLGkCILFSTH 194
|
|
| ABC_phnC |
TIGR02315 |
phosphonate ABC transporter, ATP-binding protein; Phosphonates are a class of ... |
3-230 |
1.07e-10 |
|
phosphonate ABC transporter, ATP-binding protein; Phosphonates are a class of phosphorus-containing organic compound with a stable direct C-P bond rather than a C-O-P linkage. A number of bacterial species have operons, typically about 14 genes in size, with genes for ATP-dependent transport of phosphonates, degradation, and regulation of the expression of the system. Members of this protein family are the ATP-binding cassette component of tripartite ABC transporters of phosphonates. [Transport and binding proteins, Anions]
Pssm-ID: 131368 [Multi-domain] Cd Length: 243 Bit Score: 62.32 E-value: 1.07e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 3 LLQLNHISKSF-DGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSG-------NVSKIKNLKLGYLTQQ 74
Cdd:TIGR02315 1 MLEVENLSKVYpNGKQALKNINLNINPGEFVAIIGPSGAGKSTLLRCINRLVEPSSGsillegtDITKLRGKKLRKLRRR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 75 MtlnsnATVFEEmskpFEHIKRMESLikeeTDWLSKHANdydsdtyktHMSRYESLSNQF---EQLEGYQYESKIktvlh 151
Cdd:TIGR02315 81 I-----GMIFQH----YNLIERLTVL----ENVLHGRLG---------YKPTWRSLLGRFseeDKERALSALERV----- 133
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 152 GLnfsEEDFNKPINDFSGGQKTRLSLAQMLLNEPDLLLLDEPTNHLDLETTKWLEDYLRYF---KGAIVIIS-HD----R 223
Cdd:TIGR02315 134 GL---ADKAYQRADQLSGGQQQRVAIARALAQQPDLILADEPIASLDPKTSKQVMDYLKRInkeDGITVIINlHQvdlaK 210
|
....*..
gi 446524717 224 YFLDKIV 230
Cdd:TIGR02315 211 KYADRIV 217
|
|
| ABC_FeS_Assembly |
cd03217 |
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of ... |
4-230 |
1.08e-10 |
|
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of iron-sulfur clusters (Fe-S) depends on multi-protein systems. The SUF system of E. coli and Erwinia chrysanthemi is important for Fe-S biogenesis under stressful conditions. The SUF system is made of six proteins: SufC is an atypical cytoplasmic ABC-ATPase, which forms a complex with SufB and SufD; SufA plays the role of a scaffold protein for assembly of iron-sulfur clusters and delivery to target proteins; SufS is a cysteine desulfurase which mobilizes the sulfur atom from cysteine and provides it to the cluster; SufE has no associated function yet.
Pssm-ID: 213184 [Multi-domain] Cd Length: 200 Bit Score: 61.39 E-value: 1.08e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 4 LQLNHISKSFDGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENY--DSGNV----SKIKNLKlgyltqqMTL 77
Cdd:cd03217 1 LEIKDLHVSVGGKEILKGVNLTIKKGEVHALMGPNGSGKSTLAKTIMGHPKYevTEGEIlfkgEDITDLP-------PEE 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 78 NSNATVFeemskpfehikrmeslikeetdwlskhandydsdtykthMSryeslsnqfeqlegYQYESKIktvlHGLNFse 157
Cdd:cd03217 74 RARLGIF---------------------------------------LA--------------FQYPPEI----PGVKN-- 94
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446524717 158 EDFNKPIND-FSGGQKTRLSLAQMLLNEPDLLLLDEPTNHLDLETTKWLEDYLRYFKG---AIVIISHDRYFLDKIV 230
Cdd:cd03217 95 ADFLRYVNEgFSGGEKKRNEILQLLLLEPDLAILDEPDSGLDIDALRLVAEVINKLREegkSVLIITHYQRLLDYIK 171
|
|
| ABC_PhnC_transporter |
cd03256 |
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; ... |
333-502 |
1.08e-10 |
|
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Phosphonates are a class of organophosphorus compounds characterized by a chemically stable carbon-to-phosphorus (C-P) bond. Phosphonates are widespread among naturally occurring compounds in all kingdoms of wildlife, but only prokaryotic microorganisms are able to cleave this bond. Certain bacteria such as E. coli can use alkylphosphonates as a phosphorus source. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213223 [Multi-domain] Cd Length: 241 Bit Score: 62.20 E-value: 1.08e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 333 VKNLEIGY--QTAITKPISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITFGANLQIGYydqKQAEFKSSKTI 410
Cdd:cd03256 3 VENLSKTYpnGKKALKDVSLSINPGEFVALIGPSGAGKSTLLRCLNGLVEPTSGSVLIDGTDINKL---KGKALRQLRRQ 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 411 LDYVWDQYPLMNEKD-IRAVL-GRF-----------LFVQDDVKKII----------------NDLSGGEKARLQLALLM 461
Cdd:cd03256 80 IGMIFQQFNLIERLSvLENVLsGRLgrrstwrslfgLFPKEEKQRALaalervglldkayqraDQLSGGQQQRVAIARAL 159
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 446524717 462 LQRDNVLILDEPTNHLDIDSKE----MLEQALQHFEGTILFVSHD 502
Cdd:cd03256 160 MQQPKLILADEPVASLDPASSRqvmdLLKRINREEGITVIVSLHQ 204
|
|
| ArpD |
COG4618 |
ABC-type protease/lipase transport system, ATPase and permease components [Intracellular ... |
339-523 |
1.16e-10 |
|
ABC-type protease/lipase transport system, ATPase and permease components [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 443660 [Multi-domain] Cd Length: 563 Bit Score: 64.38 E-value: 1.16e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 339 GYQTAITKPISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITF-GANLqigyydqkqaefkssktildYVWDq 417
Cdd:COG4618 342 GSKRPILRGVSFSLEPGEVLGVIGPSGSGKSTLARLLVGVWPPTAGSVRLdGADL--------------------SQWD- 400
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 418 yplmnekdiRAVLGRFL--------------------FVQDDVKKII---------------------------NDLSGG 450
Cdd:COG4618 401 ---------REELGRHIgylpqdvelfdgtiaeniarFGDADPEKVVaaaklagvhemilrlpdgydtrigeggARLSGG 471
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446524717 451 EKARLQLALLMLQRDNVLILDEPTNHLDIDSKEMLEQALQHFE---GTILFVSHdRYFINQLANKVfdLTIDGGKM 523
Cdd:COG4618 472 QRQRIGLARALYGDPRLVVLDEPNSNLDDEGEAALAAAIRALKargATVVVITH-RPSLLAAVDKL--LVLRDGRV 544
|
|
| COG4559 |
COG4559 |
ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism]; |
331-479 |
1.34e-10 |
|
ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443620 [Multi-domain] Cd Length: 258 Bit Score: 62.06 E-value: 1.34e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 331 MHVKNLEIGY-QTAITKPISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYIT-FGANLQigyyDQKQAE----- 403
Cdd:COG4559 2 LEAENLSVRLgGRTLLDDVSLTLRPGELTAIIGPNGAGKSTLLKLLTGELTPSSGEVRlNGRPLA----AWSPWElarrr 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 404 ------------FksskTILDYV------WDQYPLMNEKDIRAVL---------GRFlfvqddvkkiINDLSGGEKARLQ 456
Cdd:COG4559 78 avlpqhsslafpF----TVEEVValgrapHGSSAAQDRQIVREALalvglahlaGRS----------YQTLSGGEQQRVQ 143
|
170 180 190
....*....|....*....|....*....|
gi 446524717 457 LALLMLQ-------RDNVLILDEPTNHLDI 479
Cdd:COG4559 144 LARVLAQlwepvdgGPRWLFLDEPTSALDL 173
|
|
| LivF |
COG0410 |
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid ... |
1-60 |
1.59e-10 |
|
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid transport and metabolism];
Pssm-ID: 440179 [Multi-domain] Cd Length: 236 Bit Score: 61.54 E-value: 1.59e-10
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 1 MILLQLNHISKSFDGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNV 60
Cdd:COG0410 1 MPMLEVENLHAGYGGIHVLHGVSLEVEEGEIVALLGRNGAGKTTLLKAISGLLPPRSGSI 60
|
|
| MdlB |
COG1132 |
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms]; |
348-501 |
1.84e-10 |
|
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];
Pssm-ID: 440747 [Multi-domain] Cd Length: 579 Bit Score: 63.65 E-value: 1.84e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 348 ISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITF-GANL----------QIGYYDQKQAEFksSKTILDyvwd 416
Cdd:COG1132 359 ISLTIPPGETVALVGPSGSGKSTLVNLLLRFYDPTSGRILIdGVDIrdltleslrrQIGVVPQDTFLF--SGTIRE---- 432
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 417 qyplmN---------EKDIRAVLgRFLFVQDDVKK-------IIND----LSGGEKARLQLALLMLQRDNVLILDEPTNH 476
Cdd:COG1132 433 -----NirygrpdatDEEVEEAA-KAAQAHEFIEAlpdgydtVVGErgvnLSGGQRQRIAIARALLKDPPILILDEATSA 506
|
170 180
....*....|....*....|....*..
gi 446524717 477 LDIDSKEMLEQALQHF-EG-TILFVSH 501
Cdd:COG1132 507 LDTETEALIQEALERLmKGrTTIVIAH 533
|
|
| ABC_putative_ATPase |
cd03269 |
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the ... |
4-110 |
1.89e-10 |
|
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the subfamily A transporters involved in drug resistance, nodulation, lipid transport, and bacteriocin and lantibiotic immunity. In eubacteria and archaea, the typical organization consists of one ABC and one or two integral membranes. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213236 [Multi-domain] Cd Length: 210 Bit Score: 60.76 E-value: 1.89e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 4 LQLNHISKSFDGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNV-------SKIKNLKLGYLTQQMT 76
Cdd:cd03269 1 LEVENVTKRFGRVTALDDISFSVEKGEIFGLLGPNGAGKTTTIRMILGIILPDSGEVlfdgkplDIAARNRIGYLPEERG 80
|
90 100 110
....*....|....*....|....*....|....*....
gi 446524717 77 LNSNATVFEEMSkpfeHIKRMESLIKEE-----TDWLSK 110
Cdd:cd03269 81 LYPKMKVIDQLV----YLAQLKGLKKEEarrriDEWLER 115
|
|
| MdlB |
COG1132 |
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms]; |
12-272 |
2.04e-10 |
|
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];
Pssm-ID: 440747 [Multi-domain] Cd Length: 579 Bit Score: 63.65 E-value: 2.04e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 12 SF---DGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNVS----KIKNLKL-------GYLTQQ--- 74
Cdd:COG1132 346 SFsypGDRPVLKDISLTIPPGETVALVGPSGSGKSTLVNLLLRFYDPTSGRILidgvDIRDLTLeslrrqiGVVPQDtfl 425
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 75 --MTL-------NSNATvFEEMskpfEHIKRMESLikeeTDWLSKHANDYDsdtykthmsryeslsnqfeqlegyqyesk 145
Cdd:COG1132 426 fsGTIrenirygRPDAT-DEEV----EEAAKAAQA----HEFIEALPDGYD----------------------------- 467
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 146 ikTVL--HGLNFSeedfnkpindfsGGQKTRLSLAQ----------MllnepdllllDEPTNHLDLETTKWLEDYL-RYF 212
Cdd:COG1132 468 --TVVgeRGVNLS------------GGQRQRIAIARallkdppiliL----------DEATSALDTETEALIQEALeRLM 523
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446524717 213 KGAIVI-ISH--------DR-YFLD--KIVTQiydvalgdvkryvGNYEEFIQQRDLYYqkRMqeYESQQAE 272
Cdd:COG1132 524 KGRTTIvIAHrlstirnaDRiLVLDdgRIVEQ-------------GTHEELLARGGLYA--RL--YRLQFGE 578
|
|
| ccmA |
TIGR01189 |
heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein ... |
14-220 |
2.12e-10 |
|
heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein encoded by ccmA in bacteria. An exception is, an arabidopsis protein. Quite likely this is encoded by an organelle. Bacterial c-type cytocromes are located on the periplasmic side of the cytoplasmic membrane. Several gene products encoded in a locus designated as 'ccm' are implicated in the transport and assembly of the functional cytochrome C. This cluster includes genes: ccmA;B;C;D;E;F;G and H. The posttranslational pathway includes the transport of heme moiety, the secretion of the apoprotein and the covalent attachment of the heme with the apoprotein. The proteins ccmA and B represent an ABC transporter; ccmC and D participate in heme transfer to ccmE, which function as a periplasmic heme chaperone. The presence of ccmF, G and H is suggested to be obligatory for the final functional assembly of cytochrome c. [Protein fate, Protein and peptide secretion and trafficking, Transport and binding proteins, Other]
Pssm-ID: 273491 [Multi-domain] Cd Length: 198 Bit Score: 60.45 E-value: 2.12e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 14 DGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNVSkiknlklgyltqqmtLNSnatvfeemskpfEH 93
Cdd:TIGR01189 11 GERMLFEGLSFTLNAGEALQVTGPNGIGKTTLLRILAGLLRPDSGEVR---------------WNG------------TP 63
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 94 IKRMESLIKEETDWLSkHAndydsDTYKTHMSRYESLS--NQFEQLEGYQYESKIKTVlhGLNFSEedfNKPINDFSGGQ 171
Cdd:TIGR01189 64 LAEQRDEPHENILYLG-HL-----PGLKPELSALENLHfwAAIHGGAQRTIEDALAAV--GLTGFE---DLPAAQLSAGQ 132
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 446524717 172 KTRLSLAQMLLNEPDLLLLDEPTNHLDLETTKWLEDYLRYF--KGAIVIIS 220
Cdd:TIGR01189 133 QRRLALARLWLSRRPLWILDEPTTALDKAGVALLAGLLRAHlaRGGIVLLT 183
|
|
| ABCC_NFT1 |
cd03369 |
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type ... |
333-501 |
2.24e-10 |
|
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type transporter 1). NFT1 belongs to the MRP (multidrug resistance-associated protein) family of ABC transporters. Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213269 [Multi-domain] Cd Length: 207 Bit Score: 60.50 E-value: 2.24e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 333 VKNLEIGYQT---AITKPISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITFGaNLQIGYYDQKqaEFKSSKT 409
Cdd:cd03369 9 VENLSVRYAPdlpPVLKNVSFKVKAGEKIGIVGRTGAGKSTLILALFRFLEAEEGKIEID-GIDISTIPLE--DLRSSLT 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 410 ILDyvwdQYPLMNEKDIRAVLGRFLFVQDD-------VKKIINDLSGGEKARLQLALLMLQRDNVLILDEPTNHLDIDSK 482
Cdd:cd03369 86 IIP----QDPTLFSGTIRSNLDPFDEYSDEeiygalrVSEGGLNLSQGQRQLLCLARALLKRPRVLVLDEATASIDYATD 161
|
170 180
....*....|....*....|.
gi 446524717 483 EMLEQAL-QHFEG-TILFVSH 501
Cdd:cd03369 162 ALIQKTIrEEFTNsTILTIAH 182
|
|
| AAA |
smart00382 |
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ... |
354-506 |
2.33e-10 |
|
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.
Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 59.31 E-value: 2.33e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 354 KGDHIAIIGPNGIGKSTLIKTIANQ-QKALNGYITFGANlqigyydqkqaefkssktildyvwdqyplmnekDIRAVLgR 432
Cdd:smart00382 1 PGEVILIVGPPGSGKTTLARALARElGPPGGGVIYIDGE---------------------------------DILEEV-L 46
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446524717 433 FLFVQDDVKKIINDLSGGEKARLQLALLMLQRDNVLILDEPTNHLDIDSKEMLEQALQHFEGTILFVSHDRYFI 506
Cdd:smart00382 47 DQLLLIIVGGKKASGSGELRLRLALALARKLKPDVLILDEITSLLDAEQEALLLLLEELRLLLLLKSEKNLTVI 120
|
|
| AbcC |
COG1135 |
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism]; |
1-60 |
2.36e-10 |
|
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 440750 [Multi-domain] Cd Length: 339 Bit Score: 62.40 E-value: 2.36e-10
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446524717 1 MIllQLNHISKSFDGED----IFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNV 60
Cdd:COG1135 1 MI--ELENLSKTFPTKGgpvtALDDVSLTIEKGEIFGIIGYSGAGKSTLIRCINLLERPTSGSV 62
|
|
| ABC_Rad50 |
cd03240 |
ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ... |
359-520 |
2.70e-10 |
|
ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ATP-binding cassette of ABC transporters, but are not associated with membrane-spanning domains. The conserved ATP-binding motifs common to Rad50 and the ABC transporter family include the Walker A and Walker B motifs, the Q loop, a histidine residue in the switch region, a D-loop, and a conserved LSGG sequence. This conserved sequence, LSGG, is the most specific and characteristic motif of this family and is thus known as the ABC signature sequence.
Pssm-ID: 213207 [Multi-domain] Cd Length: 204 Bit Score: 60.31 E-value: 2.70e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 359 AIIGPNGIGKSTLIKTIAnqqkalngYITFGANLQIGYYDQKQAEFKSSKTILDYVWDQYPLMNEKDIR-----AVLGRF 433
Cdd:cd03240 26 LIVGQNGAGKTTIIEALK--------YALTGELPPNSKGGAHDPKLIREGEVRAQVKLAFENANGKKYTitrslAILENV 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 434 LFV-QDDVKKIIND----LSGGEKA------RLQLALLMLQRDNVLILDEPTNHLDIDSK-----EMLEQALQHFEGTIL 497
Cdd:cd03240 98 IFChQGESNWPLLDmrgrCSGGEKVlasliiRLALAETFGSNCGILALDEPTTNLDEENIeeslaEIIEERKSQKNFQLI 177
|
170 180
....*....|....*....|...
gi 446524717 498 FVSHDRYFInQLANKVFDLTIDG 520
Cdd:cd03240 178 VITHDEELV-DAADHIYRVEKDG 199
|
|
| ABC_CcmA_heme_exporter |
cd03231 |
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the ... |
348-517 |
2.75e-10 |
|
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the bacterial CcmAB transporter. The CCM family is involved in bacterial cytochrome c biogenesis. Cytochrome c maturation in E. coli requires the ccm operon, which encodes eight membrane proteins (CcmABCDEFGH). CcmE is a periplasmic heme chaperon that binds heme covalently and transfers it onto apocytochrome c in the presence of CcmF, CcmG, and CcmH. The CcmAB proteins represent an ABC transporter and the CcmCD proteins participate in heme transfer to CcmE.
Pssm-ID: 213198 [Multi-domain] Cd Length: 201 Bit Score: 60.20 E-value: 2.75e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 348 ISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITF---GANLQIGYYDQK------QAEFKSSKTILDYVWDQY 418
Cdd:cd03231 19 LSFTLAAGEALQVTGPNGSGKTTLLRILAGLSPPLAGRVLLnggPLDFQRDSIARGllylghAPGIKTTLSVLENLRFWH 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 419 PLMNEKDIRAVLGRF-LFVQDDVkkIINDLSGGEKARLQLALLMLQRDNVLILDEPTNHLDIDSKEMLEQAL-QHFE--G 494
Cdd:cd03231 99 ADHSDEQVEEALARVgLNGFEDR--PVAQLSAGQQRRVALARLLLSGRPLWILDEPTTALDKAGVARFAEAMaGHCArgG 176
|
170 180
....*....|....*....|...
gi 446524717 495 TILFVSHDRYFINQLANKVFDLT 517
Cdd:cd03231 177 MVVLTTHQDLGLSEAGARELDLG 199
|
|
| ABCC_Glucan_exporter_like |
cd03254 |
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan ... |
334-522 |
2.93e-10 |
|
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan exporter ATP-binding protein. In A. tumefaciens cyclic beta-1, 2-glucan must be transported into the periplasmic space to exert its action as a virulence factor. This subfamily belongs to the MRP-like family and is involved in drug, peptide, and lipid export. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains each composed of six transmembrane (TM) helices and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213221 [Multi-domain] Cd Length: 229 Bit Score: 60.70 E-value: 2.93e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 334 KNLEIGY--QTAITKPISIEVSKGDHIAIIGPNGIGKSTLIKTIanqqkaLNGYITFGANLQIGYYDQKQAEFKSSKTIL 411
Cdd:cd03254 6 ENVNFSYdeKKPVLKDINFSIKPGETVAIVGPTGAGKTTLINLL------MRFYDPQKGQILIDGIDIRDISRKSLRSMI 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 412 DYVWdQYPLMNEKDIRA--VLGRFLFVQDDVKKII------------------------NDLSGGEKARLQLALLMLQRD 465
Cdd:cd03254 80 GVVL-QDTFLFSGTIMEniRLGRPNATDEEVIEAAkeagahdfimklpngydtvlgengGNLSQGERQLLAIARAMLRDP 158
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 446524717 466 NVLILDEPTNHLDIDSKEMLEQALQH-FEGTILFVSHDRYFINQLANKVfdLTIDGGK 522
Cdd:cd03254 159 KILILDEATSNIDTETEKLIQEALEKlMKGRTSIIIAHRLSTIKNADKI--LVLDDGK 214
|
|
| GguA |
NF040905 |
sugar ABC transporter ATP-binding protein; |
3-52 |
3.00e-10 |
|
sugar ABC transporter ATP-binding protein;
Pssm-ID: 468840 [Multi-domain] Cd Length: 500 Bit Score: 62.88 E-value: 3.00e-10
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 446524717 3 LLQLNHISKSFDGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGV 52
Cdd:NF040905 1 ILEMRGITKTFPGVKALDDVNLSVREGEIHALCGENGAGKSTLMKVLSGV 50
|
|
| ABC_HisP_GlnQ |
cd03262 |
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ... |
346-522 |
3.36e-10 |
|
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ATP-binding components of the bacterial periplasmic histidine and glutamine permeases, respectively. Histidine permease is a multi-subunit complex containing the HisQ and HisM integral membrane subunits and two copies of HisP. HisP has properties intermediate between those of integral and peripheral membrane proteins and is accessible from both sides of the membrane, presumably by its interaction with HisQ and HisM. The two HisP subunits form a homodimer within the complex. The domain structure of the amino acid uptake systems is typical for prokaryotic extracellular solute binding protein-dependent uptake systems. All of the amino acid uptake systems also have at least one, and in a few cases, two extracellular solute binding proteins located in the periplasm of Gram-negative bacteria, or attached to the cell membrane of Gram-positive bacteria. The best-studied member of the PAAT (polar amino acid transport) family is the HisJQMP system of S. typhimurium, where HisJ is the extracellular solute binding proteins and HisP is the ABC protein.
Pssm-ID: 213229 [Multi-domain] Cd Length: 213 Bit Score: 60.24 E-value: 3.36e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 346 KPISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITFGaNLQIGYYDQKQAEFKSS-------------KTILD 412
Cdd:cd03262 17 KGIDLTVKKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTIIID-GLKLTDDKKNINELRQKvgmvfqqfnlfphLTVLE 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 413 -------YVWDqyplMNEKDIRAVLGRFLF---VQDDVKKIINDLSGGEKARLQLALLMLQRDNVLILDEPTNHLDID-S 481
Cdd:cd03262 96 nitlapiKVKG----MSKAEAEERALELLEkvgLADKADAYPAQLSGGQQQRVAIARALAMNPKVMLFDEPTSALDPElV 171
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 446524717 482 KEMLE--QALQHfEG-TILFVSHDRYFINQLANKVfdLTIDGGK 522
Cdd:cd03262 172 GEVLDvmKDLAE-EGmTMVVVTHEMGFAREVADRV--IFMDDGR 212
|
|
| sufC |
TIGR01978 |
FeS assembly ATPase SufC; SufC is part of the SUF system, shown in E. coli to consist of six ... |
331-520 |
3.40e-10 |
|
FeS assembly ATPase SufC; SufC is part of the SUF system, shown in E. coli to consist of six proteins and believed to act in Fe-S cluster formation during oxidative stress. SufC forms a complex with SufB and SufD. SufC belongs to the ATP-binding cassette transporter family (pfam00005) but is no longer thought to be part of a transporter. The complex is reported as cytosolic () or associated with the membrane (). The SUF system also includes a cysteine desulfurase (SufS, enhanced by SufE) and a probable iron-sulfur cluster assembly scaffold protein, SufA. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other]
Pssm-ID: 273907 [Multi-domain] Cd Length: 243 Bit Score: 60.74 E-value: 3.40e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 331 MHVKNL--EIGYQtAITKPISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQK--ALNGYITF-GANL---------QIGY 396
Cdd:TIGR01978 1 LKIKDLhvSVEDK-EILKGVNLTVKKGEIHAIMGPNGSGKSTLSKTIAGHPSyeVTSGTILFkGQDLlelepderaRAGL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 397 YDQKQA----------EF-KSSKTILDYVWDQYPL--MN-EKDIRAVLGRFLFVQDDVKKIIND-LSGGEKARLQLALLM 461
Cdd:TIGR01978 80 FLAFQYpeeipgvsnlEFlRSALNARRSARGEEPLdlLDfEKLLKEKLALLDMDEEFLNRSVNEgFSGGEKKRNEILQMA 159
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446524717 462 LQRDNVLILDEPTNHLDIDSKEMLEQALQHF---EGTILFVSHDRYFINQLANKVFDLTIDG 520
Cdd:TIGR01978 160 LLEPKLAILDEIDSGLDIDALKIVAEGINRLrepDRSFLIITHYQRLLNYIKPDYVHVLLDG 221
|
|
| CP_lyasePhnL |
TIGR02324 |
phosphonate C-P lyase system protein PhnL; Members of this family are the PhnL protein of C-P ... |
3-236 |
4.07e-10 |
|
phosphonate C-P lyase system protein PhnL; Members of this family are the PhnL protein of C-P lyase systems for utilization of phosphonates. These systems resemble phosphonatase-based systems in having a three component ABC transporter, where TIGR01097 is the permease, TIGR01098 is the phosphonates binding protein, and TIGR02315 is the ATP-binding cassette (ABC) protein. They differ, however, in having, typically, ten or more additional genes, many of which are believed to form a membrane-associated C-P lysase complex. This protein (PhnL) and the adjacent-encoded PhnK (TIGR02323) resemble transporter ATP-binding proteins but are suggested, based on mutatgenesis studies, to be part of this C-P lyase complex rather than part of a transporter per se.
Pssm-ID: 131377 [Multi-domain] Cd Length: 224 Bit Score: 60.10 E-value: 4.07e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 3 LLQLNHISKSFDGED-------IFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGveNY--DSGnvsKIKNLKLGYLTq 73
Cdd:TIGR02324 1 LLEVEDLSKTFTLHQqggvrlpVLKNVSLTVNAGECVALSGPSGAGKSTLLKSLYA--NYlpDSG---RILVRHEGAWV- 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 74 qmtlnsnatvfeEMSKPFEHikRMESLIKEETDWLSKhandydsdtYKTHMSRYESLSNQFEQLE--GYQYE---SKIKT 148
Cdd:TIGR02324 75 ------------DLAQASPR--EVLEVRRKTIGYVSQ---------FLRVIPRVSALEVVAEPLLerGVPREaarARARE 131
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 149 VLHGLNFSEEDFNKPINDFSGGQKTRLSLAQMLLNEPDLLLLDEPTNHLDLETTKWLEDYLRYFKG---AIVIISHDRYF 225
Cdd:TIGR02324 132 LLARLNIPERLWHLPPATFSGGEQQRVNIARGFIADYPILLLDEPTASLDAANRQVVVELIAEAKArgaALIGIFHDEEV 211
|
250
....*....|.
gi 446524717 226 LDKIVTQIYDV 236
Cdd:TIGR02324 212 RELVADRVMDV 222
|
|
| COG4559 |
COG4559 |
ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism]; |
3-51 |
4.07e-10 |
|
ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443620 [Multi-domain] Cd Length: 258 Bit Score: 60.90 E-value: 4.07e-10
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 446524717 3 LLQLNHISKSFDGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAG 51
Cdd:COG4559 1 MLEAENLSVRLGGRTLLDDVSLTLRPGELTAIIGPNGAGKSTLLKLLTG 49
|
|
| CeuD |
COG4604 |
ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and ... |
331-507 |
4.25e-10 |
|
ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443654 [Multi-domain] Cd Length: 252 Bit Score: 60.48 E-value: 4.25e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 331 MHVKNLEIGY-QTAITKPISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITFgANLQIGYYDQ---------- 399
Cdd:COG4604 2 IEIKNVSKRYgGKVVLDDVSLTIPKGGITALIGPNGAGKSTLLSMISRLLPPDSGEVLV-DGLDVATTPSrelakrlail 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 400 KQAEFKSSK-TILDYV-WDQYPL----MNEKDIRAV---LgRFLFVQDDVKKIINDLSGGEKARLQLALLMLQRDNVLIL 470
Cdd:COG4604 81 RQENHINSRlTVRELVaFGRFPYskgrLTAEDREIIdeaI-AYLDLEDLADRYLDELSGGQRQRAFIAMVLAQDTDYVLL 159
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 446524717 471 DEPTNHLDID-SKEM---LEQALQHFEGTILFVSHDryfIN 507
Cdd:COG4604 160 DEPLNNLDMKhSVQMmklLRRLADELGKTVVIVLHD---IN 197
|
|
| PhnK |
COG1101 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
4-60 |
4.97e-10 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 440718 [Multi-domain] Cd Length: 264 Bit Score: 60.48 E-value: 4.97e-10
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446524717 4 LQLNHISKSF-----DGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNV 60
Cdd:COG1101 2 LELKNLSKTFnpgtvNEKRALDGLNLTIEEGDFVTVIGSNGAGKSTLLNAIAGSLPPDSGSI 63
|
|
| phnK |
PRK11701 |
phosphonate C-P lyase system protein PhnK; Provisional |
3-222 |
6.61e-10 |
|
phosphonate C-P lyase system protein PhnK; Provisional
Pssm-ID: 183280 [Multi-domain] Cd Length: 258 Bit Score: 60.32 E-value: 6.61e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 3 LLQLNHISKSFDGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNVSkiknlklgYLTQQMTLNSNAT 82
Cdd:PRK11701 6 LLSVRGLTKLYGPRKGCRDVSFDLYPGEVLGIVGESGSGKTTLLNALSARLAPDAGEVH--------YRMRDGQLRDLYA 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 83 vfeeMSkpfEHIKRMesLIKeeTDWLSKHANdyDSDTYKTHMSryeSLSNQFEQL--EGYQYESKIK-TVLHGLNFSEED 159
Cdd:PRK11701 78 ----LS---EAERRR--LLR--TEWGFVHQH--PRDGLRMQVS---AGGNIGERLmaVGARHYGDIRaTAGDWLERVEID 141
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446524717 160 FNKpIND----FSGGQKTRLSLAQMLLNEPDLLLLDEPTNHLDLETTKWLEDYLRY----FKGAIVIISHD 222
Cdd:PRK11701 142 AAR-IDDlpttFSGGMQQRLQIARNLVTHPRLVFMDEPTGGLDVSVQARLLDLLRGlvreLGLAVVIVTHD 211
|
|
| PRK13536 |
PRK13536 |
nodulation factor ABC transporter ATP-binding protein NodI; |
1-198 |
6.94e-10 |
|
nodulation factor ABC transporter ATP-binding protein NodI;
Pssm-ID: 237419 [Multi-domain] Cd Length: 340 Bit Score: 61.00 E-value: 6.94e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 1 MILLQLNHISKSFDGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNVS----------KIKNLKLGY 70
Cdd:PRK13536 39 TVAIDLAGVSKSYGDKAVVNGLSFTVASGECFGLLGPNGAGKSTIARMILGMTSPDAGKITvlgvpvparaRLARARIGV 118
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 71 LTQQMTLNSNATVFEEMskpfehikrmesLIkeetdwlskhandydsdtykthMSRYESLSNQfeqlegyqyesKIKTVL 150
Cdd:PRK13536 119 VPQFDNLDLEFTVRENL------------LV----------------------FGRYFGMSTR-----------EIEAVI 153
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 446524717 151 HGL-NFS--EEDFNKPINDFSGGQKTRLSLAQMLLNEPDLLLLDEPTNHLD 198
Cdd:PRK13536 154 PSLlEFArlESKADARVSDLSGGMKRRLTLARALINDPQLLILDEPTTGLD 204
|
|
| araG |
PRK11288 |
L-arabinose ABC transporter ATP-binding protein AraG; |
4-61 |
7.52e-10 |
|
L-arabinose ABC transporter ATP-binding protein AraG;
Pssm-ID: 183077 [Multi-domain] Cd Length: 501 Bit Score: 61.85 E-value: 7.52e-10
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 446524717 4 LQLNHISKSFDGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNVS 61
Cdd:PRK11288 5 LSFDGIGKTFPGVKALDDISFDCRAGQVHALMGENGAGKSTLLKILSGNYQPDAGSIL 62
|
|
| btuD |
PRK09536 |
corrinoid ABC transporter ATPase; Reviewed |
333-480 |
8.37e-10 |
|
corrinoid ABC transporter ATPase; Reviewed
Pssm-ID: 236554 [Multi-domain] Cd Length: 402 Bit Score: 61.01 E-value: 8.37e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 333 VKNLEIGY-QTAITKPISIEVSKGDHIAIIGPNGIGKSTLIKTIanqqkalNGYITFGANLQIgyYDQKQAEFKSSKTI- 410
Cdd:PRK09536 6 VSDLSVEFgDTTVLDGVDLSVREGSLVGLVGPNGAGKTTLLRAI-------NGTLTPTAGTVL--VAGDDVEALSARAAs 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 411 --LDYVWDQYPLMNEKDIRAV--------LGRFLFVQDD-----------------VKKIINDLSGGEKARLQLALLMLQ 463
Cdd:PRK09536 77 rrVASVPQDTSLSFEFDVRQVvemgrtphRSRFDTWTETdraaveramertgvaqfADRPVTSLSGGERQRVLLARALAQ 156
|
170
....*....|....*..
gi 446524717 464 RDNVLILDEPTNHLDID 480
Cdd:PRK09536 157 ATPVLLLDEPTASLDIN 173
|
|
| ABCG_White |
cd03234 |
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ... |
344-478 |
1.03e-09 |
|
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ABC transporters homologous to the Drosophila white gene, which acts as a dimeric importer for eye pigment precursors. The eye pigmentation of Drosophila is developed from the synthesis and deposition in the cells of red pigments, which are synthesized from guanine, and brown pigments, which are synthesized from tryptophan. The pigment precursors are encoded by the white, brown, and scarlet genes, respectively. Evidence from genetic and biochemical studies suggest that the White and Brown proteins function as heterodimers to import guanine, while the White and Scarlet proteins function to import tryptophan. However, a recent study also suggests that White may be involved in the transport of a metabolite, such as 3-hydroxykynurenine, across intracellular membranes. Mammalian ABC transporters belonging to the White subfamily (ABCG1, ABCG5, and ABCG8) have been shown to be involved in the regulation of lipid-trafficking mechanisms in macrophages, hepatocytes, and intestinal mucosa cells. ABCG1 (ABC8), the human homolog of the Drosophila white gene is induced in monocyte-derived macrophages during cholesterol influx mediated by acetylated low-density lipoprotein. It is possible that human ABCG1 forms heterodimers with several heterologous partners.
Pssm-ID: 213201 [Multi-domain] Cd Length: 226 Bit Score: 59.21 E-value: 1.03e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 344 ITKPISIEVSKGDHIAIIGPNGIGKSTLIKTIAnqQKALNGYITFGanlQIgYYDQKQAEFKSSKTILDYVwDQ------ 417
Cdd:cd03234 22 ILNDVSLHVESGQVMAILGSSGSGKTTLLDAIS--GRVEGGGTTSG---QI-LFNGQPRKPDQFQKCVAYV-RQddillp 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 418 ---------YPLMN---------EKDIRAVLGRFLFVQDDV--KKIINDLSGGEKARLQLALLMLQRDNVLILDEPTNHL 477
Cdd:cd03234 95 gltvretltYTAILrlprkssdaIRKKRVEDVLLRDLALTRigGNLVKGISGGERRRVSIAVQLLWDPKVLILDEPTSGL 174
|
.
gi 446524717 478 D 478
Cdd:cd03234 175 D 175
|
|
| ycf16 |
CHL00131 |
sulfate ABC transporter protein; Validated |
2-230 |
1.08e-09 |
|
sulfate ABC transporter protein; Validated
Pssm-ID: 214372 [Multi-domain] Cd Length: 252 Bit Score: 59.27 E-value: 1.08e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 2 ILLQLNHISKSFDGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYD--SGNVsKIKNLKLGYLTQQMtlNS 79
Cdd:CHL00131 6 PILEIKNLHASVNENEILKGLNLSINKGEIHAIMGPNGSGKSTLSKVIAGHPAYKilEGDI-LFKGESILDLEPEE--RA 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 80 NATVFEEMSKPFEhikrmeslIKEETDwlskhaNDYDSDTYKThmSRYESLSNQFEQLEGYQYeskIKTVLHGLNFSEED 159
Cdd:CHL00131 83 HLGIFLAFQYPIE--------IPGVSN------ADFLRLAYNS--KRKFQGLPELDPLEFLEI---INEKLKLVGMDPSF 143
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446524717 160 FNKPIND-FSGGQKTRLSLAQMLLNEPDLLLLDEPTNHLDLETTKWLEDYLRYFKG---AIVIISHDRYFLDKIV 230
Cdd:CHL00131 144 LSRNVNEgFSGGEKKRNEILQMALLDSELAILDETDSGLDIDALKIIAEGINKLMTsenSIILITHYQRLLDYIK 218
|
|
| PRK10762 |
PRK10762 |
D-ribose transporter ATP binding protein; Provisional |
3-502 |
1.16e-09 |
|
D-ribose transporter ATP binding protein; Provisional
Pssm-ID: 236755 [Multi-domain] Cd Length: 501 Bit Score: 61.17 E-value: 1.16e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 3 LLQLNHISKSFDGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNVS---KIKNLK---------LGY 70
Cdd:PRK10762 4 LLQLKGIDKAFPGVKALSGAALNVYPGRVMALVGENGAGKSTMMKVLTGIYTRDAGSILylgKEVTFNgpkssqeagIGI 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 71 LTQQMTLNSNATVFE------EMSKPFEHI--KRMesliKEETDWLSKHAN-DYDSDTykthmsryeslsnqfeqlegyq 141
Cdd:PRK10762 84 IHQELNLIPQLTIAEniflgrEFVNRFGRIdwKKM----YAEADKLLARLNlRFSSDK---------------------- 137
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 142 yeskiktvlhglnfseedfnkPINDFSGGQKTRLSLAQMLLNEPDLLLLDEPTNHL-DLETTKWLE--DYLRYFKGAIVI 218
Cdd:PRK10762 138 ---------------------LVGELSIGEQQMVEIAKVLSFESKVIIMDEPTDALtDTETESLFRviRELKSQGRGIVY 196
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 219 ISHDryfLDKIVTQIYDVA-LGDVKryvgnyeeFIQQRDLyyqKRMQEyesqqaeikrlETFVEKNITrastsgmaksrR 297
Cdd:PRK10762 197 ISHR---LKEIFEICDDVTvFRDGQ--------FIAEREV---ADLTE-----------DSLIEMMVG-----------R 240
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 298 KILEKMERIDKPmldaksaniqfgfdrnTGNDVMHVKNLeigyqtaiTKP----ISIEVSKGDHIAIIGPNGIGKSTLIK 373
Cdd:PRK10762 241 KLEDQYPRLDKA----------------PGEVRLKVDNL--------SGPgvndVSFTLRKGEILGVSGLMGAGRTELMK 296
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 374 TIANQQKALNGYITF------------GANLQIGYY--DQK--------QAEFKSSKTILDYVWDQYPLMNEKDIRAVLG 431
Cdd:PRK10762 297 VLYGALPRTSGYVTLdghevvtrspqdGLANGIVYIseDRKrdglvlgmSVKENMSLTALRYFSRAGGSLKHADEQQAVS 376
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 432 RF--LFvqdDVK-----KIINDLSGGEKARLQLALLMLQRDNVLILDEPTNHLDIDSKEMLEQALQHF--EG-TILFVSH 501
Cdd:PRK10762 377 DFirLF---NIKtpsmeQAIGLLSGGNQQKVAIARGLMTRPKVLILDEPTRGVDVGAKKEIYQLINQFkaEGlSIILVSS 453
|
.
gi 446524717 502 D 502
Cdd:PRK10762 454 E 454
|
|
| ABC_Class2 |
cd03227 |
ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems ... |
347-502 |
1.50e-09 |
|
ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems involved in cellular processes other than transport. These families are characterized by the fact that the ABC subunit is made up of duplicated, fused ABC modules (ABC2). No known transmembrane proteins or domains are associated with these proteins.
Pssm-ID: 213194 [Multi-domain] Cd Length: 162 Bit Score: 57.37 E-value: 1.50e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 347 PISIEVSKGDHIAIIGPNGIGKSTLIKTIanqqkalnGYITFGANLQIG-YYDQKQAEFKSsktildyvwdqyplmnekD 425
Cdd:cd03227 13 PNDVTFGEGSLTIITGPNGSGKSTILDAI--------GLALGGAQSATRrRSGVKAGCIVA------------------A 66
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 426 IRAVLgRFLFVQddvkkiindLSGGEKARLQLALLM----LQRDNVLILDEPTNHLDIDSKEMLEQALQHF---EGTILF 498
Cdd:cd03227 67 VSAEL-IFTRLQ---------LSGGEKELSALALILalasLKPRPLYILDEIDRGLDPRDGQALAEAILEHlvkGAQVIV 136
|
....
gi 446524717 499 VSHD 502
Cdd:cd03227 137 ITHL 140
|
|
| ABCC_MRP_domain1 |
cd03250 |
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This ... |
348-522 |
1.54e-09 |
|
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This subfamily is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213217 [Multi-domain] Cd Length: 204 Bit Score: 58.25 E-value: 1.54e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 348 ISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITFGANlqIGYYDQK---QaefksSKTILD-YVWDQYplMNE 423
Cdd:cd03250 24 INLEVPKGELVAIVGPVGSGKSSLLSALLGELEKLSGSVSVPGS--IAYVSQEpwiQ-----NGTIREnILFGKP--FDE 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 424 KDIRAVLGRFLFVQD-------DVKKI----INdLSGGEKARLQLALLMLQRDNVLILDEPTNHLDID-SKEMLEQALQH 491
Cdd:cd03250 95 ERYEKVIKACALEPDleilpdgDLTEIgekgIN-LSGGQKQRISLARAVYSDADIYLLDDPLSAVDAHvGRHIFENCILG 173
|
170 180 190
....*....|....*....|....*....|....
gi 446524717 492 F---EGTILFVSHDRYFINQlANKVfdLTIDGGK 522
Cdd:cd03250 174 LllnNKTRILVTHQLQLLPH-ADQI--VVLDNGR 204
|
|
| btuD |
PRK09536 |
corrinoid ABC transporter ATPase; Reviewed |
1-199 |
1.61e-09 |
|
corrinoid ABC transporter ATPase; Reviewed
Pssm-ID: 236554 [Multi-domain] Cd Length: 402 Bit Score: 60.24 E-value: 1.61e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 1 MILLQLNHISKSFDGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNVS----KIKNLKLGYLTQQMt 76
Cdd:PRK09536 1 MPMIDVSDLSVEFGDTTVLDGVDLSVREGSLVGLVGPNGAGKTTLLRAINGTLTPTAGTVLvagdDVEALSARAASRRV- 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 77 lnsnATVFEEMSKPFEHikRMESLIKeetdwLSKHAndydsdtyktHMSRYESLSnqfeqlegyqyESKIKTVLHGLNFS 156
Cdd:PRK09536 80 ----ASVPQDTSLSFEF--DVRQVVE-----MGRTP----------HRSRFDTWT-----------ETDRAAVERAMERT 127
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 446524717 157 EED--FNKPINDFSGGQKTRLSLAQMLLNEPDLLLLDEPTNHLDL 199
Cdd:PRK09536 128 GVAqfADRPVTSLSGGERQRVLLARALAQATPVLLLDEPTASLDI 172
|
|
| COG4586 |
COG4586 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
348-527 |
1.61e-09 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 443643 [Multi-domain] Cd Length: 323 Bit Score: 59.72 E-value: 1.61e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 348 ISIEVSKGDHIAIIGPNGIGKSTLIK-----------TIAnqqkaLNGYITFganlqigyydQKQAEFKSS-------KT 409
Cdd:COG4586 41 ISFTIEPGEIVGFIGPNGAGKSTTIKmltgilvptsgEVR-----VLGYVPF----------KRRKEFARRigvvfgqRS 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 410 ILDY---VWDQYPL------MNEKDIRAVLGRF--LFvqdDVKKIIND----LSGGEKARLQLALLMLQRDNVLILDEPT 474
Cdd:COG4586 106 QLWWdlpAIDSFRLlkaiyrIPDAEYKKRLDELveLL---DLGELLDTpvrqLSLGQRMRCELAAALLHRPKILFLDEPT 182
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 446524717 475 NHLDIDSKEMLEQAL----QHFEGTILFVSHDRYFINQLANKVfdLTIDGGK-MYLGD 527
Cdd:COG4586 183 IGLDVVSKEAIREFLkeynRERGTTILLTSHDMDDIEALCDRV--IVIDHGRiIYDGS 238
|
|
| nickel_nikE |
TIGR02769 |
nickel import ATP-binding protein NikE; This family represents the NikE subunit of a ... |
18-230 |
1.79e-09 |
|
nickel import ATP-binding protein NikE; This family represents the NikE subunit of a multisubunit nickel import ABC transporter complex. Nickel, once imported, may be used in urease and in certain classes of hydrogenase and superoxide dismutase. [Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 131816 [Multi-domain] Cd Length: 265 Bit Score: 59.05 E-value: 1.79e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 18 IFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNVS---------KIKNLKLGYLTQQMtlnsnatVFEEMS 88
Cdd:TIGR02769 26 VLTNVSLSIEEGETVGLLGRSGCGKSTLARLLLGLEKPAQGTVSfrgqdlyqlDRKQRRAFRRDVQL-------VFQDSP 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 89 KPFEHIKRMESLIKEEtdwlskhandydsdtykthMSRYESLSNQfEQLEgyqyesKIKTVLHGLNFSEEDFNKPINDFS 168
Cdd:TIGR02769 99 SAVNPRMTVRQIIGEP-------------------LRHLTSLDES-EQKA------RIAELLDMVGLRSEDADKLPRQLS 152
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 169 GGQKTRLSLAQMLLNEPDLLLLDEPTNHLDL----ETTKWLEDYLRYFKGAIVIISHD----RYFLDKIV 230
Cdd:TIGR02769 153 GGQLQRINIARALAVKPKLIVLDEAVSNLDMvlqaVILELLRKLQQAFGTAYLFITHDlrlvQSFCQRVA 222
|
|
| ABC_MetN_methionine_transporter |
cd03258 |
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ... |
346-522 |
2.03e-09 |
|
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ABC-type transporter encoded by metN of the metNPQ operon in Bacillus subtilis that is involved in methionine transport. Other members of this system include the MetP permease and the MetQ substrate binding protein. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213225 [Multi-domain] Cd Length: 233 Bit Score: 58.36 E-value: 2.03e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 346 KPISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYIT-FGANL-------------QIGYYDQkQAEFKSSKTIL 411
Cdd:cd03258 22 KDVSLSVPKGEIFGIIGRSGAGKSTLIRCINGLERPTSGSVLvDGTDLtllsgkelrkarrRIGMIFQ-HFNLLSSRTVF 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 412 DYVwdQYPL------MNEKDIRAV-LGRFLFVQDDVKKIINDLSGGEKARLQLALLMLQRDNVLILDEPTNHLDIDSK-- 482
Cdd:cd03258 101 ENV--ALPLeiagvpKAEIEERVLeLLELVGLEDKADAYPAQLSGGQKQRVGIARALANNPKVLLCDEATSALDPETTqs 178
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 446524717 483 --EMLEQALQHFEGTILFVSHDRYFINQLANKVfdLTIDGGK 522
Cdd:cd03258 179 ilALLRDINRELGLTIVLITHEMEVVKRICDRV--AVMEKGE 218
|
|
| PRK09700 |
PRK09700 |
D-allose ABC transporter ATP-binding protein AlsA; |
3-286 |
2.46e-09 |
|
D-allose ABC transporter ATP-binding protein AlsA;
Pssm-ID: 182036 [Multi-domain] Cd Length: 510 Bit Score: 60.18 E-value: 2.46e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 3 LLQLNHISKSFDGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNVSkIKNLKLGYLTQQM-TLNSNA 81
Cdd:PRK09700 5 YISMAGIGKSFGPVHALKSVNLTVYPGEIHALLGENGAGKSTLMKVLSGIHEPTKGTIT-INNINYNKLDHKLaAQLGIG 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 82 TVFEEMskpfehikrmeSLIKEetdwLSKHANDYdsdtYKTHMSRYESLSNQFEQLEgYQYESKIKTVLHGLnfsEEDFN 161
Cdd:PRK09700 84 IIYQEL-----------SVIDE----LTVLENLY----IGRHLTKKVCGVNIIDWRE-MRVRAAMMLLRVGL---KVDLD 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 162 KPINDFSGGQKTRLSLAQMLLNEPDLLLLDEPTNHLDLETTKWLEDYLRYFKG---AIVIISH---------DRYFLDKI 229
Cdd:PRK09700 141 EKVANLSISHKQMLEIAKTLMLDAKVIIMDEPTSSLTNKEVDYLFLIMNQLRKegtAIVYISHklaeirricDRYTVMKD 220
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446524717 230 VTQIY-----DVALGD-VKRYVGnyeefiqqRDLyyQKRMQEYESQQAEIKRLETFVEKNITR 286
Cdd:PRK09700 221 GSSVCsgmvsDVSNDDiVRLMVG--------REL--QNRFNAMKENVSNLAHETVFEVRNVTS 273
|
|
| PRK10908 |
PRK10908 |
cell division ATP-binding protein FtsE; |
332-526 |
2.80e-09 |
|
cell division ATP-binding protein FtsE;
Pssm-ID: 182829 [Multi-domain] Cd Length: 222 Bit Score: 57.58 E-value: 2.80e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 332 HVKNLEIGYQTAItKPISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITFGAN--------------LQIGYY 397
Cdd:PRK10908 6 HVSKAYLGGRQAL-QGVTFHMRPGEMAFLTGHSGAGKSTLLKLICGIERPSAGKIWFSGHditrlknrevpflrRQIGMI 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 398 DQKQaEFKSSKTILDYVwdQYPLM----NEKDIR----AVLGRFLFVqDDVKKIINDLSGGEKARLQLALLMLQRDNVLI 469
Cdd:PRK10908 85 FQDH-HLLMDRTVYDNV--AIPLIiagaSGDDIRrrvsAALDKVGLL-DKAKNFPIQLSGGEQQRVGIARAVVNKPAVLL 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446524717 470 LDEPTNHLDidsKEMLEQALQHFEG------TILFVSHDRYFINQLANKVfdLTIDGGKMYLG 526
Cdd:PRK10908 161 ADEPTGNLD---DALSEGILRLFEEfnrvgvTVLMATHDIGLISRRSYRM--LTLSDGHLHGG 218
|
|
| potA |
PRK09452 |
spermidine/putrescine ABC transporter ATP-binding protein PotA; |
3-60 |
2.91e-09 |
|
spermidine/putrescine ABC transporter ATP-binding protein PotA;
Pssm-ID: 236523 [Multi-domain] Cd Length: 375 Bit Score: 59.19 E-value: 2.91e-09
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 446524717 3 LLQLNHISKSFDGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNV 60
Cdd:PRK09452 14 LVELRGISKSFDGKEVISNLDLTINNGEFLTLLGPSGCGKTTVLRLIAGFETPDSGRI 71
|
|
| ABC_RNaseL_inhibitor_domain1 |
cd03236 |
The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ... |
355-502 |
3.30e-09 |
|
The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI s are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLIs have an N-terminal Fe-S domain and two nucleotide binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.
Pssm-ID: 213203 [Multi-domain] Cd Length: 255 Bit Score: 58.15 E-value: 3.30e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 355 GDHIAIIGPNGIGKSTLIKTIANQQK----------ALNGYITF--GANLQIGYYDQKQAEFKSSKTIlDYVwDQYP--- 419
Cdd:cd03236 26 GQVLGLVGPNGIGKSTALKILAGKLKpnlgkfddppDWDEILDEfrGSELQNYFTKLLEGDVKVIVKP-QYV-DLIPkav 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 420 ------LMNEKDIRAVLGRfLFVQDDVKKI----INDLSGGEKARLQLALLMLQRDNVLILDEPTNHLDIdsKEMLEQA- 488
Cdd:cd03236 104 kgkvgeLLKKKDERGKLDE-LVDQLELRHVldrnIDQLSGGELQRVAIAAALARDADFYFFDEPSSYLDI--KQRLNAAr 180
|
170
....*....|....*...
gi 446524717 489 ----LQHFEGTILFVSHD 502
Cdd:cd03236 181 lireLAEDDNYVLVVEHD 198
|
|
| znuC |
PRK09544 |
high-affinity zinc transporter ATPase; Reviewed |
1-79 |
3.37e-09 |
|
high-affinity zinc transporter ATPase; Reviewed
Pssm-ID: 181939 [Multi-domain] Cd Length: 251 Bit Score: 57.82 E-value: 3.37e-09
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446524717 1 MILLQLNHISKSFDGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNVSKIKNLKLGYLTQQMTLNS 79
Cdd:PRK09544 2 TSLVSLENVSVSFGQRRVLSDVSLELKPGKILTLLGPNGAGKSTLVRVVLGLVAPDEGVIKRNGKLRIGYVPQKLYLDT 80
|
|
| CydD |
TIGR02857 |
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family ... |
20-231 |
3.63e-09 |
|
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex. Unfortunately, the gene symbol nomenclature adopted based on this operon in B. subtilis assigns cydC to the third gene in the operon where this gene is actually homologous to the E. coli cydD gene. We have chosen to name all homologs in this family in accordance with the precedence of publication of the E. coli name, CydD
Pssm-ID: 274323 [Multi-domain] Cd Length: 529 Bit Score: 59.61 E-value: 3.63e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 20 TDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNVSkiknlklgyltqqmtLNSNatvfeemskPFEHIKrmES 99
Cdd:TIGR02857 339 RPVSFTVPPGERVALVGPSGAGKSTLLNLLLGFVDPTEGSIA---------------VNGV---------PLADAD--AD 392
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 100 LIKEETDWLSKHAndydsdtyktHMSrYESLSNQFEQLEGYQYESKIKTVLH--GLNFSEED----FNKPIND----FSG 169
Cdd:TIGR02857 393 SWRDQIAWVPQHP----------FLF-AGTIAENIRLARPDASDAEIREALEraGLDEFVAAlpqgLDTPIGEggagLSG 461
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446524717 170 GQKTRLSLAQMLLNEPDLLLLDEPTNHLDLETTKWLEDYLR-YFKGAIV-IISHDR---YFLDKIVT 231
Cdd:TIGR02857 462 GQAQRLALARAFLRDAPLLLLDEPTAHLDAETEAEVLEALRaLAQGRTVlLVTHRLalaALADRIVV 528
|
|
| ABCC_cytochrome_bd |
cd03247 |
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome ... |
4-91 |
4.39e-09 |
|
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome bd biogenesis. The CydC and CydD proteins are important for the formation of cytochrome bd terminal oxidase of E. coli and it has been proposed that they were necessary for biosynthesis of the cytochrome bd quinol oxidase and for periplasmic c-type cytochromes. CydCD were proposed to determine a heterooligomeric complex important for heme export into the periplasm or to be involved in the maintenance of the proper redox state of the periplasmic space. In Bacillus subtilis, the absence of CydCD does not affect the presence of halo-cytochrome c in the membrane and this observation suggests that CydCD proteins are not involved in the export of heme in this organism.
Pssm-ID: 213214 [Multi-domain] Cd Length: 178 Bit Score: 56.17 E-value: 4.39e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 4 LQLNHISKSFDGED--IFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSG-------NVSKIKNL---KLGYL 71
Cdd:cd03247 1 LSINNVSFSYPEQEqqVLKNLSLELKQGEKIALLGRSGSGKSTLLQLLTGDLKPQQGeitldgvPVSDLEKAlssLISVL 80
|
90 100
....*....|....*....|
gi 446524717 72 TQQMTLnSNATVFEEMSKPF 91
Cdd:cd03247 81 NQRPYL-FDTTLRNNLGRRF 99
|
|
| COG4586 |
COG4586 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
21-61 |
4.53e-09 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 443643 [Multi-domain] Cd Length: 323 Bit Score: 58.17 E-value: 4.53e-09
10 20 30 40
....*....|....*....|....*....|....*....|.
gi 446524717 21 DVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNVS 61
Cdd:COG4586 40 DISFTIEPGEIVGFIGPNGAGKSTTIKMLTGILVPTSGEVR 80
|
|
| PRK10584 |
PRK10584 |
putative ABC transporter ATP-binding protein YbbA; Provisional |
3-222 |
4.54e-09 |
|
putative ABC transporter ATP-binding protein YbbA; Provisional
Pssm-ID: 182569 [Multi-domain] Cd Length: 228 Bit Score: 57.10 E-value: 4.54e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 3 LLQLNHISKSF-DGE---DIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNVS---------------KI 63
Cdd:PRK10584 6 IVEVHHLKKSVgQGEhelSILTGVELVVKRGETIALIGESGSGKSTLLAILAGLDDGSSGEVSlvgqplhqmdeearaKL 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 64 KNLKLGYLTQQMTLNSNATVFEEMSKPfehikrmeSLIKEETDwlskhandydsdtyktHMSRyeslsnqfeqlegyqye 143
Cdd:PRK10584 86 RAKHVGFVFQSFMLIPTLNALENVELP--------ALLRGESS----------------RQSR----------------- 124
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 144 SKIKTVLHGLNFSEEDFNKPINdFSGGQKTRLSLAQMLLNEPDLLLLDEPTNHLDLETTKWLEDYL----RYFKGAIVII 219
Cdd:PRK10584 125 NGAKALLEQLGLGKRLDHLPAQ-LSGGEQQRVALARAFNGRPDVLFADEPTGNLDRQTGDKIADLLfslnREHGTTLILV 203
|
...
gi 446524717 220 SHD 222
Cdd:PRK10584 204 THD 206
|
|
| TauB |
COG1116 |
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion ... |
1-222 |
5.36e-09 |
|
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440733 [Multi-domain] Cd Length: 260 Bit Score: 57.41 E-value: 5.36e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 1 MILLQLNHISKSFDGED----IFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNVS------KIKNLKLGY 70
Cdd:COG1116 5 APALELRGVSKRFPTGGggvtALDDVSLTVAAGEFVALVGPSGCGKSTLLRLIAGLEKPTSGEVLvdgkpvTGPGPDRGV 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 71 LTQQMTLNSNATVFE---------EMSKPfEHIKRMESLIkEETDwLSKHANDYDSdtykthmsryeslsnqfeQLegyq 141
Cdd:COG1116 85 VFQEPALLPWLTVLDnvalglelrGVPKA-ERRERARELL-ELVG-LAGFEDAYPH------------------QL---- 139
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 142 yeskiktvlhglnfseedfnkpindfSGGQKTRLSLAQMLLNEPDLLLLDEPTNHLDlETTK-----WLEDYLRYFKGAI 216
Cdd:COG1116 140 --------------------------SGGMRQRVAIARALANDPEVLLMDEPFGALD-ALTRerlqdELLRLWQETGKTV 192
|
....*.
gi 446524717 217 VIISHD 222
Cdd:COG1116 193 LFVTHD 198
|
|
| ABC_NatA_like |
cd03267 |
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; ... |
21-222 |
5.69e-09 |
|
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled to proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of the single ATP-binding protein and the single integral membrane protein.
Pssm-ID: 213234 [Multi-domain] Cd Length: 236 Bit Score: 56.96 E-value: 5.69e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 21 DVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNVSkiknlKLGYLtqqmtlnsnatvfeemskPFE----HIKR 96
Cdd:cd03267 39 GISFTIEKGEIVGFIGPNGAGKTTTLKILSGLLQPTSGEVR-----VAGLV------------------PWKrrkkFLRR 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 97 MeSLI---KEETDW-LSKhandydSDTYKTHMSRYeslsnqfeQLEGYQYESKIKTVLHGLNFsEEDFNKPINDFSGGQK 172
Cdd:cd03267 96 I-GVVfgqKTQLWWdLPV------IDSFYLLAAIY--------DLPPARFKKRLDELSELLDL-EELLDTPVRQLSLGQR 159
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 446524717 173 TRLSLAQMLLNEPDLLLLDEPTNHLDLETT----KWLEDYLRYFKGAIVIISHD 222
Cdd:cd03267 160 MRAEIAAALLHEPEILFLDEPTIGLDVVAQenirNFLKEYNRERGTTVLLTSHY 213
|
|
| PRK14239 |
PRK14239 |
phosphate transporter ATP-binding protein; Provisional |
330-517 |
7.49e-09 |
|
phosphate transporter ATP-binding protein; Provisional
Pssm-ID: 184585 [Multi-domain] Cd Length: 252 Bit Score: 57.09 E-value: 7.49e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 330 VMHVKNLEIGY-QTAITKPISIEVSKGDHIAIIGPNGIGKSTLIKTIaNQQKALN------GYITF-GANL--------- 392
Cdd:PRK14239 5 ILQVSDLSVYYnKKKALNSVSLDFYPNEITALIGPSGSGKSTLLRSI-NRMNDLNpevtitGSIVYnGHNIysprtdtvd 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 393 ---QIGYYDQKQAEFKSSktILDYVWDQYPLMNEKDiRAVLGRFL-------FVQDDVKKIIND----LSGGEKARLQLA 458
Cdd:PRK14239 84 lrkEIGMVFQQPNPFPMS--IYENVVYGLRLKGIKD-KQVLDEAVekslkgaSIWDEVKDRLHDsalgLSGGQQQRVCIA 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446524717 459 LLMLQRDNVLILDEPTNHLDIDSKEMLEQALQHFEG--TILFVSHDRyfinQLANKVFDLT 517
Cdd:PRK14239 161 RVLATSPKIILLDEPTSALDPISAGKIEETLLGLKDdyTMLLVTRSM----QQASRISDRT 217
|
|
| cbiO |
PRK13635 |
energy-coupling factor ABC transporter ATP-binding protein; |
328-524 |
7.62e-09 |
|
energy-coupling factor ABC transporter ATP-binding protein;
Pssm-ID: 184195 [Multi-domain] Cd Length: 279 Bit Score: 57.33 E-value: 7.62e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 328 NDVMHVKNLEIGYQTAIT---KPISIEVSKGDHIAIIGPNGIGKSTLiktianqQKALNGYITFGANLqIGYYDQKQAEf 404
Cdd:PRK13635 3 EEIIRVEHISFRYPDAATyalKDVSFSVYEGEWVAIVGHNGSGKSTL-------AKLLNGLLLPEAGT-ITVGGMVLSE- 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 405 kssktilDYVWDqyplmnekdIRAVLGrFLF-----------VQDDVK--------------KIIND------------- 446
Cdd:PRK13635 74 -------ETVWD---------VRRQVG-MVFqnpdnqfvgatVQDDVAfglenigvpreemvERVDQalrqvgmedflnr 136
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 447 ----LSGGEKARLQLALLMLQRDNVLILDEPTNHLD-IDSKEMLE--QALQHFEG-TILFVSHDryfINQLANKVFDLTI 518
Cdd:PRK13635 137 ephrLSGGQKQRVAIAGVLALQPDIIILDEATSMLDpRGRREVLEtvRQLKEQKGiTVLSITHD---LDEAAQADRVIVM 213
|
....*.
gi 446524717 519 DGGKMY 524
Cdd:PRK13635 214 NKGEIL 219
|
|
| CydC |
TIGR02868 |
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family ... |
4-222 |
7.87e-09 |
|
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex.
Pssm-ID: 274331 [Multi-domain] Cd Length: 530 Bit Score: 58.53 E-value: 7.87e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 4 LQLNHISKSFDG-EDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNVskiknlklgyltqqmTLNSNAT 82
Cdd:TIGR02868 335 LELRDLSAGYPGaPPVLDGVSLDLPPGERVAILGPSGSGKSTLLATLAGLLDPLQGEV---------------TLDGVPV 399
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 83 vfeeMSKPFEHIKRMESLIKEEtdwlskhANDYDSDTYKTHMSRYESLSNQ--FEQLEGYQYESKIKTVLHGLNfseedf 160
Cdd:TIGR02868 400 ----SSLDQDEVRRRVSVCAQD-------AHLFDTTVRENLRLARPDATDEelWAALERVGLADWLRALPDGLD------ 462
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446524717 161 nKPIND----FSGGQKTRLSLAQMLLNEPDLLLLDEPTNHLDLETTK-WLEDYLRYFKG-AIVIISHD 222
Cdd:TIGR02868 463 -TVLGEggarLSGGERQRLALARALLADAPILLLDEPTEHLDAETADeLLEDLLAALSGrTVVLITHH 529
|
|
| ABC_ThiQ_thiamine_transporter |
cd03298 |
ATP-binding cassette domain of the thiamine transport system; Part of the ... |
349-523 |
8.13e-09 |
|
ATP-binding cassette domain of the thiamine transport system; Part of the binding-protein-dependent transport system tbpA-thiPQ for thiamine and TPP. Probably responsible for the translocation of thiamine across the membrane. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213265 [Multi-domain] Cd Length: 211 Bit Score: 56.35 E-value: 8.13e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 349 SIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITfganlqIGYYDQKQAEfkSSKTILDYVWDQYPL-------- 420
Cdd:cd03298 18 DLTFAQGEITAIVGPSGSGKSTLLNLIAGFETPQSGRVL------INGVDVTAAP--PADRPVSMLFQENNLfahltveq 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 421 -----------MNEKD---IRAVLGRfLFVQDDVKKIINDLSGGEKARLQLALLMLQRDNVLILDEPTNHLD-IDSKEML 485
Cdd:cd03298 90 nvglglspglkLTAEDrqaIEVALAR-VGLAGLEKRLPGELSGGERQRVALARVLVRDKPVLLLDEPFAALDpALRAEML 168
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 446524717 486 EQAL---QHFEGTILFVSHDRYFINQLANKVfdLTIDGGKM 523
Cdd:cd03298 169 DLVLdlhAETKMTVLMVTHQPEDAKRLAQRV--VFLDNGRI 207
|
|
| ntrCD |
TIGR01184 |
nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits ... |
346-502 |
8.80e-09 |
|
nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits of nitrate transport in bacteria and archaea. This protein belongs to the ATP-binding cassette (ABC) superfamily. It is thought that the two subunits encoded by ntrC and ntrD form the binding surface for interaction with ATP. This model is restricted in identifying ATP binding subunit associated with the nitrate transport. Nitrate assimilation is aided by other proteins derived from the operon which among others include products of ntrA - a regulatory protein; ntrB - a hydropbobic transmembrane permease and narB - a reductase. [Transport and binding proteins, Anions, Transport and binding proteins, Other]
Pssm-ID: 130252 [Multi-domain] Cd Length: 230 Bit Score: 56.32 E-value: 8.80e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 346 KPISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITF--------GANLQIGYYDQKQAEFKSSK-TILDYVWD 416
Cdd:TIGR01184 2 KGVNLTIQQGEFISLIGHSGCGKSTLLNLISGLAQPTSGGVILegkqitepGPDRMVVFQNYSLLPWLTVReNIALAVDR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 417 QYPLMNEKDIRAVLGRFLFV---QDDVKKIINDLSGGEKARLQLALLMLQRDNVLILDEPTNHLDIDSKEMLEQAL---- 489
Cdd:TIGR01184 82 VLPDLSKSERRAIVEEHIALvglTEAADKRPGQLSGGMKQRVAIARALSIRPKVLLLDEPFGALDALTRGNLQEELmqiw 161
|
170
....*....|...
gi 446524717 490 QHFEGTILFVSHD 502
Cdd:TIGR01184 162 EEHRVTVLMVTHD 174
|
|
| ABCC_Protease_Secretion |
cd03246 |
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of ... |
4-221 |
1.05e-08 |
|
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of the protease secretion system PrtD, a 60-kDa integral membrane protein sharing 37% identity with HlyB, the ABC component of the alpha-hemolysin secretion pathway, in the C-terminal domain. They export degradative enzymes by using a type I protein secretion system and lack an N-terminal signal peptide, but contain a C-terminal secretion signal. The Type I secretion apparatus is made up of three components, an ABC transporter, a membrane fusion protein (MFP), and an outer membrane protein (OMP). For the HlyA transporter complex, HlyB (ABC transporter) and HlyD (MFP) reside in the inner membrane of E. coli. The OMP component is TolC, which is thought to interact with the MFP to form a continuous channel across the periplasm from the cytoplasm to the exterior. HlyB belongs to the family of ABC transporters, which are ubiquitous, ATP-dependent transmembrane pumps or channels. The spectrum of transport substrates ranges from inorganic ions, nutrients such as amino acids, sugars, or peptides, hydrophobic drugs, to large polypeptides, such as HlyA.
Pssm-ID: 213213 [Multi-domain] Cd Length: 173 Bit Score: 54.92 E-value: 1.05e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 4 LQLNHISKSFDGED--IFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNVsKIKNLKLgyltqqmtlnsna 81
Cdd:cd03246 1 LEVENVSFRYPGAEppVLRNVSFSIEPGESLAIIGPSGSGKSTLARLILGLLRPTSGRV-RLDGADI------------- 66
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 82 tvfeemskpfehikrmeslikeetdwlskhaNDYDSDTYKTHMsryeslsnqfeqleGYqyeskiktvlhgLNFSEEDFN 161
Cdd:cd03246 67 -------------------------------SQWDPNELGDHV--------------GY------------LPQDDELFS 89
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446524717 162 KPIND--FSGGQKTRLSLAQMLLNEPDLLLLDEPTNHLDLETTKWLEDYLRYFKGA---IVIISH 221
Cdd:cd03246 90 GSIAEniLSGGQRQRLGLARALYGNPRILVLDEPNSHLDVEGERALNQAIAALKAAgatRIVIAH 154
|
|
| ABCC_MsbA |
cd03251 |
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; ... |
14-260 |
1.12e-08 |
|
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; MsbA is an essential ABC transporter, closely related to eukaryotic MDR proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213218 [Multi-domain] Cd Length: 234 Bit Score: 56.09 E-value: 1.12e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 14 DGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNVS----KIKNLKLGYLTQQMTLNS------NATV 83
Cdd:cd03251 13 DGPPVLRDISLDIPAGETVALVGPSGSGKSTLVNLIPRFYDVDSGRILidghDVRDYTLASLRRQIGLVSqdvflfNDTV 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 84 FEEM--SKPFEHIKRMESLIKeetdwlSKHANDYdsdtykthmsrYESLSNQFEQLEGyqyESKIKtvlhglnfseedfn 161
Cdd:cd03251 93 AENIayGRPGATREEVEEAAR------AANAHEF-----------IMELPEGYDTVIG---ERGVK-------------- 138
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 162 kpindFSGGQKTRLSLAQMLLNEPDLLLLDEPTNHLDLETTKWLEDYLRYF---KGAIVI------ISHdryfLDKIVT- 231
Cdd:cd03251 139 -----LSGGQRQRIAIARALLKDPPILILDEATSALDTESERLVQAALERLmknRTTFVIahrlstIEN----ADRIVVl 209
|
250 260 270
....*....|....*....|....*....|..
gi 446524717 232 ---QIydvalgdVKRyvGNYEEFIQQRDLYYQ 260
Cdd:cd03251 210 edgKI-------VER--GTHEELLAQGGVYAK 232
|
|
| MsbA_lipidA |
TIGR02203 |
lipid A export permease/ATP-binding protein MsbA; This family consists of a single polypeptide ... |
348-501 |
1.13e-08 |
|
lipid A export permease/ATP-binding protein MsbA; This family consists of a single polypeptide chain transporter in the ATP-binding cassette (ABC) transporter family, MsbA, which exports lipid A. It may also act in multidrug resistance. Lipid A, a part of lipopolysaccharide, is found in the outer leaflet of the outer membrane of most Gram-negative bacteria. Members of this family are restricted to the Proteobacteria (although lipid A is more broadly distributed) and often are clustered with lipid A biosynthesis genes. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides, Transport and binding proteins, Other]
Pssm-ID: 131258 [Multi-domain] Cd Length: 571 Bit Score: 58.19 E-value: 1.13e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 348 ISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITFG---------ANL--QIGYYDQKQAEFksSKTILDYV-- 414
Cdd:TIGR02203 351 ISLVIEPGETVALVGRSGSGKSTLVNLIPRFYEPDSGQILLDghdladytlASLrrQVALVSQDVVLF--NDTIANNIay 428
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 415 --WDQYPlmnEKDIRAVLgRFLFVQDDVKKIIN-----------DLSGGEKARLQLALLMLQRDNVLILDEPTNHLDIDS 481
Cdd:TIGR02203 429 grTEQAD---RAEIERAL-AAAYAQDFVDKLPLgldtpigengvLLSGGQRQRLAIARALLKDAPILILDEATSALDNES 504
|
170 180
....*....|....*....|..
gi 446524717 482 KEMLEQALQHF--EGTILFVSH 501
Cdd:TIGR02203 505 ERLVQAALERLmqGRTTLVIAH 526
|
|
| ModC |
COG4148 |
ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and ... |
359-523 |
1.13e-08 |
|
ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and metabolism]; ABC-type molybdate transport system, ATPase component ModC is part of the Pathway/BioSystem: Molybdopterin biosynthesis
Pssm-ID: 443319 [Multi-domain] Cd Length: 358 Bit Score: 57.42 E-value: 1.13e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 359 AIIGPNGIGKSTLIKTIANQQKALNGYITF-GANLQ--------------IGY------------------YDQKQAEFK 405
Cdd:COG4148 29 ALFGPSGSGKTTLLRAIAGLERPDSGRIRLgGEVLQdsargiflpphrrrIGYvfqearlfphlsvrgnllYGRKRAPRA 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 406 SSKTILDYVWDqypLMnekDIRAVLGRFlfvqddvkkiINDLSGGEKARLQL--ALLMLQRdnVLILDEPTNHLDIDSKE 483
Cdd:COG4148 109 ERRISFDEVVE---LL---GIGHLLDRR----------PATLSGGERQRVAIgrALLSSPR--LLLMDEPLAALDLARKA 170
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 446524717 484 ----MLEQALQHFEGTILFVSHDRYFINQLANKVfdLTIDGGKM 523
Cdd:COG4148 171 eilpYLERLRDELDIPILYVSHSLDEVARLADHV--VLLEQGRV 212
|
|
| ABC_CcmA_heme_exporter |
cd03231 |
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the ... |
14-221 |
1.24e-08 |
|
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the bacterial CcmAB transporter. The CCM family is involved in bacterial cytochrome c biogenesis. Cytochrome c maturation in E. coli requires the ccm operon, which encodes eight membrane proteins (CcmABCDEFGH). CcmE is a periplasmic heme chaperon that binds heme covalently and transfers it onto apocytochrome c in the presence of CcmF, CcmG, and CcmH. The CcmAB proteins represent an ABC transporter and the CcmCD proteins participate in heme transfer to CcmE.
Pssm-ID: 213198 [Multi-domain] Cd Length: 201 Bit Score: 55.58 E-value: 1.24e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 14 DGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNVSkiknlklgyltqqmtLNSNATVFEEMSkpfeh 93
Cdd:cd03231 11 DGRALFSGLSFTLAAGEALQVTGPNGSGKTTLLRILAGLSPPLAGRVL---------------LNGGPLDFQRDS----- 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 94 ikrmeslIKEETDWLSkHANdydsdTYKTHMSRYESLsnQFeqLEGYQYESKIKTVLH--GLNFSEedfNKPINDFSGGQ 171
Cdd:cd03231 71 -------IARGLLYLG-HAP-----GIKTTLSVLENL--RF--WHADHSDEQVEEALArvGLNGFE---DRPVAQLSAGQ 130
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 446524717 172 KTRLSLAQMLLNEPDLLLLDEPTNHLDLETTKWLEDYLRYF---KGAIVIISH 221
Cdd:cd03231 131 QRRVALARLLLSGRPLWILDEPTTALDKAGVARFAEAMAGHcarGGMVVLTTH 183
|
|
| ABC_MTABC3_MDL1_MDL2 |
cd03249 |
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 ... |
332-501 |
1.35e-08 |
|
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 (also known as ABCB6) is a mitochondrial ATP-binding cassette protein involved in iron homeostasis and one of four ABC transporters expressed in the mitochondrial inner membrane, the other three being MDL1(ABC7), MDL2, and ATM1. In fact, the yeast MDL1 (multidrug resistance-like protein 1) and MDL2 (multidrug resistance-like protein 2) transporters are also included in this CD. MDL1 is an ATP-dependent permease that acts as a high-copy suppressor of ATM1 and is thought to have a role in resistance to oxidative stress. Interestingly, subfamily B is more closely related to the carboxyl-terminal component of subfamily C than the two halves of ABCC molecules are with one another.
Pssm-ID: 213216 [Multi-domain] Cd Length: 238 Bit Score: 56.01 E-value: 1.35e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 332 HVKNLEIGYQT----AITKPISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITFGA------NL-----QIGY 396
Cdd:cd03249 2 EFKNVSFRYPSrpdvPILKGLSLTIPPGKTVALVGSSGCGKSTVVSLLERFYDPTSGEILLDGvdirdlNLrwlrsQIGL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 397 YDQKQAEFksSKTILDyvwdqyplmnekDIRavLGRFLFVQDDVK---------KIIND---------------LSGGEK 452
Cdd:cd03249 82 VSQEPVLF--DGTIAE------------NIR--YGKPDATDEEVEeaakkanihDFIMSlpdgydtlvgergsqLSGGQK 145
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 446524717 453 ARLQLALLMLQRDNVLILDEPTNHLDIDSKEMLEQALQHF-EG-TILFVSH 501
Cdd:cd03249 146 QRIAIARALLRNPKILLLDEATSALDAESEKLVQEALDRAmKGrTTIVIAH 196
|
|
| F420-0_ABC_ATP |
TIGR03873 |
proposed F420-0 ABC transporter, ATP-binding protein; This small clade of ABC-type transporter ... |
4-199 |
1.38e-08 |
|
proposed F420-0 ABC transporter, ATP-binding protein; This small clade of ABC-type transporter ATP-binding protein components is found as a three gene cassette along with a periplasmic substrate-binding protein (TIGR03868) and a permease (TIGR03869). The organisms containing this cassette are all Actinobacteria and all contain numerous genes requiring the coenzyme F420. This model was defined based on five such organisms, four of which are lacking all F420 biosynthetic capability save the final side-chain polyglutamate attachment step (via the gene cofE: TIGR01916). In Jonesia denitrificans DSM 20603 and marine actinobacterium PHSC20C1 this cassette is in an apparent operon with the cofE gene and, in PHSC20C1, also with a F420-dependent glucose-6-phosphate dehydrogenase (TIGR03554). Based on these observations we propose that this ATP-binding protein is a component of an F420-0 (that is, F420 lacking only the polyglutamate tail) transporter.
Pssm-ID: 163585 [Multi-domain] Cd Length: 256 Bit Score: 56.36 E-value: 1.38e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 4 LQLNHISKSFDGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNVS-----------KIKNLKLGYLT 72
Cdd:TIGR03873 2 LRLSRVSWSAGGRLIVDGVDVTAPPGSLTGLLGPNGSGKSTLLRLLAGALRPDAGTVDlagvdlhglsrRARARRVALVE 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 73 QQMTLNSNATVFEEMS---KPFEhikrmeSLIKEETDWLSKHANDYDSDTYKTHMSryeslsnqfeqlegyqyeskiktv 149
Cdd:TIGR03873 82 QDSDTAVPLTVRDVVAlgrIPHR------SLWAGDSPHDAAVVDRALARTELSHLA------------------------ 131
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 446524717 150 lhglnfseedfNKPINDFSGGQKTRLSLAQMLLNEPDLLLLDEPTNHLDL 199
Cdd:TIGR03873 132 -----------DRDMSTLSGGERQRVHVARALAQEPKLLLLDEPTNHLDV 170
|
|
| ABCC_MsbA |
cd03251 |
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; ... |
334-491 |
1.55e-08 |
|
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; MsbA is an essential ABC transporter, closely related to eukaryotic MDR proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213218 [Multi-domain] Cd Length: 234 Bit Score: 55.70 E-value: 1.55e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 334 KNLEIGYQ---TAITKPISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITF-GANL----------QIGYYDQ 399
Cdd:cd03251 4 KNVTFRYPgdgPPVLRDISLDIPAGETVALVGPSGSGKSTLVNLIPRFYDVDSGRILIdGHDVrdytlaslrrQIGLVSQ 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 400 KQAEFksSKTILDYVWDQYPLMNEKDIRAVLgRFLFVQDDVKK-------IIND----LSGGEKARLQLALLMLQRDNVL 468
Cdd:cd03251 84 DVFLF--NDTVAENIAYGRPGATREEVEEAA-RAANAHEFIMElpegydtVIGErgvkLSGGQRQRIAIARALLKDPPIL 160
|
170 180
....*....|....*....|...
gi 446524717 469 ILDEPTNHLDIDSKEMLEQALQH 491
Cdd:cd03251 161 ILDEATSALDTESERLVQAALER 183
|
|
| PRK10908 |
PRK10908 |
cell division ATP-binding protein FtsE; |
3-223 |
1.56e-08 |
|
cell division ATP-binding protein FtsE;
Pssm-ID: 182829 [Multi-domain] Cd Length: 222 Bit Score: 55.65 E-value: 1.56e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 3 LLQLNHISKSF-DGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSG-------NVSKIKNLKLGYLTQQ 74
Cdd:PRK10908 1 MIRFEHVSKAYlGGRQALQGVTFHMRPGEMAFLTGHSGAGKSTLLKLICGIERPSAGkiwfsghDITRLKNREVPFLRRQ 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 75 MTLnsnatVFEemskpfEHIKRMESLIkeetdwlskhandYDSdtykthmsryESLSNQFEQLEGYQYESKIKTVLHGLN 154
Cdd:PRK10908 81 IGM-----IFQ------DHHLLMDRTV-------------YDN----------VAIPLIIAGASGDDIRRRVSAALDKVG 126
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446524717 155 FSEEDFNKPINdFSGGQKTRLSLAQMLLNEPDLLLLDEPTNHLDLETTkwlEDYLRYFK-----GAIVII-SHDR 223
Cdd:PRK10908 127 LLDKAKNFPIQ-LSGGEQQRVGIARAVVNKPAVLLADEPTGNLDDALS---EGILRLFEefnrvGVTVLMaTHDI 197
|
|
| lolD |
PRK11629 |
lipoprotein-releasing ABC transporter ATP-binding protein LolD; |
2-222 |
1.78e-08 |
|
lipoprotein-releasing ABC transporter ATP-binding protein LolD;
Pssm-ID: 183244 [Multi-domain] Cd Length: 233 Bit Score: 55.59 E-value: 1.78e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 2 ILLQLNHISKSF-DGE---DIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNV---------------SK 62
Cdd:PRK11629 4 ILLQCDNLCKRYqEGSvqtDVLHNVSFSIGEGEMMAIVGSSGSGKSTLLHLLGGLDTPTSGDVifngqpmsklssaakAE 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 63 IKNLKLGYLTQQMTLNSNATVFEEMSKPFehikrmesLIKeetdwlskhandydsdtyktHMSRYESLSNQFEQLEGYQY 142
Cdd:PRK11629 84 LRNQKLGFIYQFHHLLPDFTALENVAMPL--------LIG--------------------KKKPAEINSRALEMLAAVGL 135
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 143 ESKIKtvlhglnfseedfNKPiNDFSGGQKTRLSLAQMLLNEPDLLLLDEPTNHLDLETTKWLEDYL----RYFKGAIVI 218
Cdd:PRK11629 136 EHRAN-------------HRP-SELSGGERQRVAIARALVNNPRLVLADEPTGNLDARNADSIFQLLgelnRLQGTAFLV 201
|
....
gi 446524717 219 ISHD 222
Cdd:PRK11629 202 VTHD 205
|
|
| ycf16 |
CHL00131 |
sulfate ABC transporter protein; Validated |
325-501 |
1.88e-08 |
|
sulfate ABC transporter protein; Validated
Pssm-ID: 214372 [Multi-domain] Cd Length: 252 Bit Score: 55.80 E-value: 1.88e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 325 NTGNDVMHVKNLEIGY-QTAITKPISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQ--KALNGYITF-GANLQigyydQK 400
Cdd:CHL00131 2 NKNKPILEIKNLHASVnENEILKGLNLSINKGEIHAIMGPNGSGKSTLSKVIAGHPayKILEGDILFkGESIL-----DL 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 401 QAEFKSSKTIldYVWDQYPL-----MNEKDIRAVLG--------------RFLFVQDDVKKIIN------------DLSG 449
Cdd:CHL00131 77 EPEERAHLGI--FLAFQYPIeipgvSNADFLRLAYNskrkfqglpeldplEFLEIINEKLKLVGmdpsflsrnvneGFSG 154
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 446524717 450 GEKAR---LQLALLmlqRDNVLILDEPTNHLDIDSKEMLEQALQHF---EGTILFVSH 501
Cdd:CHL00131 155 GEKKRneiLQMALL---DSELAILDETDSGLDIDALKIIAEGINKLmtsENSIILITH 209
|
|
| PRK13539 |
PRK13539 |
cytochrome c biogenesis protein CcmA; Provisional |
15-220 |
2.11e-08 |
|
cytochrome c biogenesis protein CcmA; Provisional
Pssm-ID: 237421 [Multi-domain] Cd Length: 207 Bit Score: 54.88 E-value: 2.11e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 15 GEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNVS----KIKNLKLG----YLTQQMTLNSNATVFEE 86
Cdd:PRK13539 14 GRVLFSGLSFTLAAGEALVLTGPNGSGKTTLLRLIAGLLPPAAGTIKldggDIDDPDVAeachYLGHRNAMKPALTVAEN 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 87 MSkpFehikrmeslikeetdWlskhandydSDTYKTHMSRYEslsnqfEQLEGYQyeskiktvLHGLnfseedFNKPIND 166
Cdd:PRK13539 94 LE--F---------------W---------AAFLGGEELDIA------AALEAVG--------LAPL------AHLPFGY 127
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 446524717 167 FSGGQKTRLSLAQMLLNEPDLLLLDEPTNHLDLETTKWLEDYLRYF--KGAIVIIS 220
Cdd:PRK13539 128 LSAGQKRRVALARLLVSNRPIWILDEPTAALDAAAVALFAELIRAHlaQGGIVIAA 183
|
|
| PRK14246 |
PRK14246 |
phosphate ABC transporter ATP-binding protein; Provisional |
343-513 |
2.22e-08 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172734 [Multi-domain] Cd Length: 257 Bit Score: 55.44 E-value: 2.22e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 343 AITKPISIEVSKGDHIAIIGPNGIGKSTLIKT------IANQQKALNGYIT-FGANL----------QIGYYDQKQAEFK 405
Cdd:PRK14246 24 AILKDITIKIPNNSIFGIMGPSGSGKSTLLKVlnrlieIYDSKIKVDGKVLyFGKDIfqidaiklrkEVGMVFQQPNPFP 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 406 --SSKTILDYVWDQYPLMNEKDIRAVL-------GRFLFVQDDVKKIINDLSGGEKARLQLALLMLQRDNVLILDEPTNH 476
Cdd:PRK14246 104 hlSIYDNIAYPLKSHGIKEKREIKKIVeeclrkvGLWKEVYDRLNSPASQLSGGQQQRLTIARALALKPKVLLMDEPTSM 183
|
170 180 190
....*....|....*....|....*....|....*....
gi 446524717 477 LDIDSKEMLEQALQHF--EGTILFVSHDRYFINQLANKV 513
Cdd:PRK14246 184 IDIVNSQAIEKLITELknEIAIVIVSHNPQQVARVADYV 222
|
|
| cbiO |
PRK13643 |
energy-coupling factor transporter ATPase; |
348-545 |
2.31e-08 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184203 [Multi-domain] Cd Length: 288 Bit Score: 55.90 E-value: 2.31e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 348 ISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITFGANLQIGYYDQKQAEFKSSKTILDYVWDQYPLMNE---K 424
Cdd:PRK13643 25 IDLEVKKGSYTALIGHTGSGKSTLLQHLNGLLQPTEGKVTVGDIVVSSTSKQKEIKPVRKKVGVVFQFPESQLFEEtvlK 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 425 DIRAVLGRFLFVQDDVKKIIN------------------DLSGGEKARLQLALLMLQRDNVLILDEPTNHLDIDSK-EML 485
Cdd:PRK13643 105 DVAFGPQNFGIPKEKAEKIAAeklemvgladefwekspfELSGGQMRRVAIAGILAMEPEVLVLDEPTAGLDPKARiEMM 184
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446524717 486 E--QALQHFEGTILFVSHdryfinqLANKVFDltidggkmyLGDYQYYIEK------------VEEAEALKAHQ 545
Cdd:PRK13643 185 QlfESIHQSGQTVVLVTH-------LMDDVAD---------YADYVYLLEKghiiscgtpsdvFQEVDFLKAHE 242
|
|
| ThiQ |
COG3840 |
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism]; |
4-61 |
2.40e-08 |
|
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];
Pssm-ID: 443051 [Multi-domain] Cd Length: 232 Bit Score: 55.15 E-value: 2.40e-08
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 446524717 4 LQLNHISKSFdGEDIFTdVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNVS 61
Cdd:COG3840 2 LRLDDLTYRY-GDFPLR-FDLTIAAGERVAILGPSGAGKSTLLNLIAGFLPPDSGRIL 57
|
|
| PRK13537 |
PRK13537 |
nodulation factor ABC transporter ATP-binding protein NodI; |
348-501 |
2.44e-08 |
|
nodulation factor ABC transporter ATP-binding protein NodI;
Pssm-ID: 237420 [Multi-domain] Cd Length: 306 Bit Score: 55.97 E-value: 2.44e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 348 ISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITF----------GANLQIGY---YDQKQAEFKSSKTILdyV 414
Cdd:PRK13537 26 LSFHVQRGECFGLLGPNGAGKTTTLRMLLGLTHPDAGSISLcgepvpsrarHARQRVGVvpqFDNLDPDFTVRENLL--V 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 415 WDQYPLMNEKDIRAV---LGRFLFVQDDVKKIINDLSGGEKARLQLALLMLQRDNVLILDEPTNHLDIDSKEMLEQALQH 491
Cdd:PRK13537 104 FGRYFGLSAAAARALvppLLEFAKLENKADAKVGELSGGMKRRLTLARALVNDPDVLVLDEPTTGLDPQARHLMWERLRS 183
|
170
....*....|...
gi 446524717 492 FEG---TILFVSH 501
Cdd:PRK13537 184 LLArgkTILLTTH 196
|
|
| ABC_DrrA |
cd03265 |
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein ... |
4-210 |
3.02e-08 |
|
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein component of a bacterial exporter complex that confers resistance to the antibiotics daunorubicin and doxorubicin. In addition to DrrA, the complex includes an integral membrane protein called DrrB. DrrA belongs to the ABC family of transporters and shares sequence and functional similarities with a protein found in cancer cells called P-glycoprotein. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213232 [Multi-domain] Cd Length: 220 Bit Score: 54.68 E-value: 3.02e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 4 LQLNHISKSFDGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGN--------VSKIKNLK--LGYLTQ 73
Cdd:cd03265 1 IEVENLVKKYGDFEAVRGVSFRVRRGEIFGLLGPNGAGKTTTIKMLTTLLKPTSGRatvaghdvVREPREVRrrIGIVFQ 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 74 QMTLNSNATVFEEMskpfehikrmesLIkeetdwlskHANDYDsdtykthmsryeslsnqfeqLEGYQYESKIKTVLHGL 153
Cdd:cd03265 81 DLSVDDELTGWENL------------YI---------HARLYG--------------------VPGAERRERIDELLDFV 119
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 446524717 154 NFSEEDfNKPINDFSGGQKTRLSLAQMLLNEPDLLLLDEPTNHLDLETTKWLEDYLR 210
Cdd:cd03265 120 GLLEAA-DRLVKTYSGGMRRRLEIARSLVHRPEVLFLDEPTIGLDPQTRAHVWEYIE 175
|
|
| cbiO |
PRK13636 |
cobalt transporter ATP-binding subunit; Provisional |
330-502 |
4.18e-08 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184196 [Multi-domain] Cd Length: 283 Bit Score: 55.24 E-value: 4.18e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 330 VMHVKNLEIGYQ--TAITKPISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITFGA---------------NL 392
Cdd:PRK13636 5 ILKVEELNYNYSdgTHALKGININIKKGEVTAILGGNGAGKSTLFQNLNGILKPSSGRILFDGkpidysrkglmklreSV 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 393 QIGYYDQKQAEFKSSKtildYVWDQYPLMN----EKDIRAVLGRFLF---VQDDVKKIINDLSGGEKARLQLALLMLQRD 465
Cdd:PRK13636 85 GMVFQDPDNQLFSASV----YQDVSFGAVNlklpEDEVRKRVDNALKrtgIEHLKDKPTHCLSFGQKKRVAIAGVLVMEP 160
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 446524717 466 NVLILDEPTNHLD-IDSKEMLEQALQHFEG---TILFVSHD 502
Cdd:PRK13636 161 KVLVLDEPTAGLDpMGVSEIMKLLVEMQKElglTIIIATHD 201
|
|
| ssuB |
PRK11247 |
aliphatic sulfonates transport ATP-binding subunit; Provisional |
4-58 |
4.18e-08 |
|
aliphatic sulfonates transport ATP-binding subunit; Provisional
Pssm-ID: 183055 [Multi-domain] Cd Length: 257 Bit Score: 54.68 E-value: 4.18e-08
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 446524717 4 LQLNHISKSFDGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSG 58
Cdd:PRK11247 13 LLLNAVSKRYGERTVLNQLDLHIPAGQFVAVVGRSGCGKSTLLRLLAGLETPSAG 67
|
|
| ThiQ |
COG3840 |
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism]; |
332-522 |
4.34e-08 |
|
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];
Pssm-ID: 443051 [Multi-domain] Cd Length: 232 Bit Score: 54.38 E-value: 4.34e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 332 HVKNLEIGYQTAiTKPISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITF-GANLQigyydqKQAEFKSSKTI 410
Cdd:COG3840 3 RLDDLTYRYGDF-PLRFDLTIAAGERVAILGPSGAGKSTLLNLIAGFLPPDSGRILWnGQDLT------ALPPAERPVSM 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 411 L--DY-------VWDQYPL-------MNEKDIRAV--------LGRFLfvqddvKKIINDLSGGEKARLQLALLMLQRDN 466
Cdd:COG3840 76 LfqENnlfphltVAQNIGLglrpglkLTAEQRAQVeqalervgLAGLL------DRLPGQLSGGQRQRVALARCLVRKRP 149
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446524717 467 VLILDEPTNHLDIDSK-EML----EQALQHfEGTILFVSHDRYFINQLANKVfdLTIDGGK 522
Cdd:COG3840 150 ILLLDEPFSALDPALRqEMLdlvdELCRER-GLTVLMVTHDPEDAARIADRV--LLVADGR 207
|
|
| ssuB |
PRK11247 |
aliphatic sulfonates transport ATP-binding subunit; Provisional |
344-519 |
4.80e-08 |
|
aliphatic sulfonates transport ATP-binding subunit; Provisional
Pssm-ID: 183055 [Multi-domain] Cd Length: 257 Bit Score: 54.68 E-value: 4.80e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 344 ITKPISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITFGANLQIGYYDQKQAEFKSS-----KTILDYV---- 414
Cdd:PRK11247 27 VLNQLDLHIPAGQFVAVVGRSGCGKSTLLRLLAGLETPSAGELLAGTAPLAEAREDTRLMFQDArllpwKKVIDNVglgl 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 415 ---WDQYPLmneKDIRAVlGrflfVQDDVKKIINDLSGGEKARLQLALLMLQRDNVLILDEPTNHLD----IDSKEMLEQ 487
Cdd:PRK11247 107 kgqWRDAAL---QALAAV-G----LADRANEWPAALSGGQKQRVALARALIHRPGLLLLDEPLGALDaltrIEMQDLIES 178
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 446524717 488 ALQHFEGTILFVSHDRYFINQLANKV---------FDLTID 519
Cdd:PRK11247 179 LWQQHGFTVLLVTHDVSEAVAMADRVllieegkigLDLTVD 219
|
|
| PRK10619 |
PRK10619 |
histidine ABC transporter ATP-binding protein HisP; |
341-516 |
5.41e-08 |
|
histidine ABC transporter ATP-binding protein HisP;
Pssm-ID: 182592 [Multi-domain] Cd Length: 257 Bit Score: 54.59 E-value: 5.41e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 341 QTAITKPISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITF-GANL--------QIGYYDQKQaeFKSSKTIL 411
Cdd:PRK10619 17 EHEVLKGVSLQANAGDVISIIGSSGSGKSTFLRCINFLEKPSEGSIVVnGQTInlvrdkdgQLKVADKNQ--LRLLRTRL 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 412 DYVWDQYPLMN-----EKDIRA---VLG--------RFLFVQDDV-------KKIINDLSGGEKARLQLALLMLQRDNVL 468
Cdd:PRK10619 95 TMVFQHFNLWShmtvlENVMEApiqVLGlskqeareRAVKYLAKVgideraqGKYPVHLSGGQQQRVSIARALAMEPEVL 174
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 446524717 469 ILDEPTNHLDID-SKEMLE--QALQHFEGTILFVSHDRYFINQLANKVFDL 516
Cdd:PRK10619 175 LFDEPTSALDPElVGEVLRimQQLAEEGKTMVVVTHEMGFARHVSSHVIFL 225
|
|
| NupO |
COG3845 |
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ... |
348-501 |
5.71e-08 |
|
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];
Pssm-ID: 443055 [Multi-domain] Cd Length: 504 Bit Score: 55.80 E-value: 5.71e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 348 ISIEVSKGD-HiAIIGPNGIGKSTLIKTIANQQKALNGYItfganlqigYYDQKQAEFKSSK------------------ 408
Cdd:COG3845 24 VSLTVRPGEiH-ALLGENGAGKSTLMKILYGLYQPDSGEI---------LIDGKPVRIRSPRdaialgigmvhqhfmlvp 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 409 --TILDYVW-----DQYPLMN----EKDIRAVLGRF-LFVqdDVKKIINDLSGGEKARLQLaLLMLQRD-NVLILDEPTN 475
Cdd:COG3845 94 nlTVAENIVlglepTKGGRLDrkaaRARIRELSERYgLDV--DPDAKVEDLSVGEQQRVEI-LKALYRGaRILILDEPTA 170
|
170 180
....*....|....*....|....*....
gi 446524717 476 HLDIDSKEMLEQALQHF--EG-TILFVSH 501
Cdd:COG3845 171 VLTPQEADELFEILRRLaaEGkSIIFITH 199
|
|
| metN |
PRK11153 |
DL-methionine transporter ATP-binding subunit; Provisional |
1-221 |
5.88e-08 |
|
DL-methionine transporter ATP-binding subunit; Provisional
Pssm-ID: 236863 [Multi-domain] Cd Length: 343 Bit Score: 55.19 E-value: 5.88e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 1 MIllQLNHISKSFDGEDI----FTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNV-------SKIKNLKL- 68
Cdd:PRK11153 1 MI--ELKNISKVFPQGGRtihaLNNVSLHIPAGEIFGVIGASGAGKSTLIRCINLLERPTSGRVlvdgqdlTALSEKELr 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 69 ------GYLTQQMTLNSNATVFEEMSKPFEHIKRMESLIKEETD------WLSKHANDYDSdtykthmsryeslsnqfeQ 136
Cdd:PRK11153 79 karrqiGMIFQHFNLLSSRTVFDNVALPLELAGTPKAEIKARVTellelvGLSDKADRYPA------------------Q 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 137 LegyqyeskiktvlhglnfseedfnkpindfSGGQKTRLSLAQMLLNEPDLLLLDEPTNHLDLETTKWLEDYL----RYF 212
Cdd:PRK11153 141 L------------------------------SGGQKQRVAIARALASNPKVLLCDEATSALDPATTRSILELLkdinREL 190
|
....*....
gi 446524717 213 KGAIVIISH 221
Cdd:PRK11153 191 GLTIVLITH 199
|
|
| PRK14243 |
PRK14243 |
phosphate transporter ATP-binding protein; Provisional |
325-528 |
6.27e-08 |
|
phosphate transporter ATP-binding protein; Provisional
Pssm-ID: 184588 [Multi-domain] Cd Length: 264 Bit Score: 54.40 E-value: 6.27e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 325 NTGNDVMHVKNLEIGYQTAIT-KPISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGY-----ITF-GANL----- 392
Cdd:PRK14243 5 NGTETVLRTENLNVYYGSFLAvKNVWLDIPKNQITAFIGPSGCGKSTILRCFNRLNDLIPGFrvegkVTFhGKNLyapdv 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 393 -------QIGYYDQKQAEFksSKTILD----------YVWDQYPLMNEKDIRAVLgrflfvQDDVKKIIND----LSGGE 451
Cdd:PRK14243 85 dpvevrrRIGMVFQKPNPF--PKSIYDniaygaringYKGDMDELVERSLRQAAL------WDEVKDKLKQsglsLSGGQ 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 452 KARLQLALLMLQRDNVLILDEPTNHLDIDS----KEMLEQALQHFegTILFVSHDRyfinQLANKVFDLTI--------D 519
Cdd:PRK14243 157 QQRLCIARAIAVQPEVILMDEPCSALDPIStlriEELMHELKEQY--TIIIVTHNM----QQAARVSDMTAffnvelteG 230
|
250
....*....|
gi 446524717 520 GGKM-YLGDY 528
Cdd:PRK14243 231 GGRYgYLVEF 240
|
|
| PRK13537 |
PRK13537 |
nodulation factor ABC transporter ATP-binding protein NodI; |
4-198 |
6.45e-08 |
|
nodulation factor ABC transporter ATP-binding protein NodI;
Pssm-ID: 237420 [Multi-domain] Cd Length: 306 Bit Score: 54.81 E-value: 6.45e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 4 LQLNHISKSFDGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNVS----------KIKNLKLGYLTQ 73
Cdd:PRK13537 8 IDFRNVEKRYGDKLVVDGLSFHVQRGECFGLLGPNGAGKTTTLRMLLGLTHPDAGSISlcgepvpsraRHARQRVGVVPQ 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 74 QMTLNSNATVFEEMskpfehikrmesLIkeetdwlskhandydsdtykthMSRYESLSNQfeqlegyQYESKIKTVLHgl 153
Cdd:PRK13537 88 FDNLDPDFTVRENL------------LV----------------------FGRYFGLSAA-------AARALVPPLLE-- 124
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 446524717 154 nFS--EEDFNKPINDFSGGQKTRLSLAQMLLNEPDLLLLDEPTNHLD 198
Cdd:PRK13537 125 -FAklENKADAKVGELSGGMKRRLTLARALVNDPDVLVLDEPTTGLD 170
|
|
| sufC |
PRK09580 |
cysteine desulfurase ATPase component; Reviewed |
3-229 |
7.18e-08 |
|
cysteine desulfurase ATPase component; Reviewed
Pssm-ID: 181965 [Multi-domain] Cd Length: 248 Bit Score: 54.03 E-value: 7.18e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 3 LLQLNHISKSFDGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENY--DSGNVS-KIKNLklgyLTQQMTLNS 79
Cdd:PRK09580 1 MLSIKDLHVSVEDKAILRGLNLEVRPGEVHAIMGPNGSGKSTLSATLAGREDYevTGGTVEfKGKDL----LELSPEDRA 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 80 NATVFEEMSKPFEhikrmeslikeetdwLSKHANDYDSDTYKTHMSRYEslsnQFEQLEGYQYESKIKTVLHGLNFSEED 159
Cdd:PRK09580 77 GEGIFMAFQYPVE---------------IPGVSNQFFLQTALNAVRSYR----GQEPLDRFDFQDLMEEKIALLKMPEDL 137
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446524717 160 FNKPIN-DFSGGQKTRLSLAQMLLNEPDLLLLDEPTNHLDLETTKWLE---DYLRYFKGAIVIISHDRYFLDKI 229
Cdd:PRK09580 138 LTRSVNvGFSGGEKKRNDILQMAVLEPELCILDESDSGLDIDALKIVAdgvNSLRDGKRSFIIVTHYQRILDYI 211
|
|
| ABCC_Hemolysin |
cd03252 |
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a ... |
14-60 |
7.19e-08 |
|
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a central component of the secretion machinery that translocates the toxin, hemolysin A, in a Sec-independent fashion across both membranes of E. coli. The hemolysin A (HlyA) transport machinery is composed of the ATP-binding cassette (ABC) transporter HlyB located in the inner membrane, hemolysin D (HlyD), also anchored in the inner membrane, and TolC, which resides in the outer membrane. HlyD apparently forms a continuous channel that bridges the entire periplasm, interacting with TolC and HlyB. This arrangement prevents the appearance of periplasmic intermediates of HlyA during substrate transport. Little is known about the molecular details of HlyA transport, but it is evident that ATP-hydrolysis by the ABC-transporter HlyB is a necessary source of energy.
Pssm-ID: 213219 [Multi-domain] Cd Length: 237 Bit Score: 53.64 E-value: 7.19e-08
10 20 30 40
....*....|....*....|....*....|....*....|....*..
gi 446524717 14 DGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNV 60
Cdd:cd03252 13 DGPVILDNISLRIKPGEVVGIVGRSGSGKSTLTKLIQRFYVPENGRV 59
|
|
| YddA |
COG4178 |
ABC-type uncharacterized transport system, permease and ATPase components [General function ... |
14-60 |
7.38e-08 |
|
ABC-type uncharacterized transport system, permease and ATPase components [General function prediction only];
Pssm-ID: 443337 [Multi-domain] Cd Length: 571 Bit Score: 55.58 E-value: 7.38e-08
10 20 30 40
....*....|....*....|....*....|....*....|....*..
gi 446524717 14 DGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNV 60
Cdd:COG4178 374 DGRPLLEDLSLSLKPGERLLITGPSGSGKSTLLRAIAGLWPYGSGRI 420
|
|
| PRK11264 |
PRK11264 |
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional |
331-548 |
7.60e-08 |
|
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional
Pssm-ID: 183063 [Multi-domain] Cd Length: 250 Bit Score: 53.99 E-value: 7.60e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 331 MHVKNLEIGYQ-TAITKPISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITFGA------------------- 390
Cdd:PRK11264 4 IEVKNLVKKFHgQTVLHGIDLEVKPGEVVAIIGPSGSGKTTLLRCINLLEQPEAGTIRVGDitidtarslsqqkglirql 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 391 NLQIGYYDQKQAEFkSSKTILDYVWDQyPLMNEKDIRA---VLGRFLFVQDDVKKIIND----LSGGEKARLQLALLMLQ 463
Cdd:PRK11264 84 RQHVGFVFQNFNLF-PHRTVLENIIEG-PVIVKGEPKEeatARARELLAKVGLAGKETSyprrLSGGQQQRVAIARALAM 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 464 RDNVLILDEPTNHLDID-SKEMLE--QALQHFEGTILFVSHDRYFINQLANKVfdLTIDGGKMylgdyqyyiekVE--EA 538
Cdd:PRK11264 162 RPEVILFDEPTSALDPElVGEVLNtiRQLAQEKRTMVIVTHEMSFARDVADRA--IFMDQGRI-----------VEqgPA 228
|
250
....*....|
gi 446524717 539 EALKAHQEEQ 548
Cdd:PRK11264 229 KALFADPQQP 238
|
|
| PRK11000 |
PRK11000 |
maltose/maltodextrin ABC transporter ATP-binding protein MalK; |
342-522 |
7.61e-08 |
|
maltose/maltodextrin ABC transporter ATP-binding protein MalK;
Pssm-ID: 182893 [Multi-domain] Cd Length: 369 Bit Score: 55.04 E-value: 7.61e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 342 TAITKPISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKalngyITFGaNLQIGyyDQKQAEFKSSKTILDYVWDQ---Y 418
Cdd:PRK11000 16 VVISKDINLDIHEGEFVVFVGPSGCGKSTLLRMIAGLED-----ITSG-DLFIG--EKRMNDVPPAERGVGMVFQSyalY 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 419 PLMNEKDIRAvLGRFLFVQD--DVKKIIN-----------------DLSGGEKARLQLALLMLQRDNVLILDEPTNHLDI 479
Cdd:PRK11000 88 PHLSVAENMS-FGLKLAGAKkeEINQRVNqvaevlqlahlldrkpkALSGGQRQRVAIGRTLVAEPSVFLLDEPLSNLDA 166
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 446524717 480 DSK-EM------LEQALQHfegTILFVSHDRYFINQLANKVFDLtiDGGK 522
Cdd:PRK11000 167 ALRvQMrieisrLHKRLGR---TMIYVTHDQVEAMTLADKIVVL--DAGR 211
|
|
| ABC_YhbG |
cd03218 |
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the ... |
344-473 |
7.85e-08 |
|
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the YhbG family are similar to members of the Mj1267_LivG family, which is involved in the transport of branched-chain amino acids. The genes yhbG and yhbN are located in a single operon and may function together in cell envelope during biogenesis. YhbG is the putative ATP-binding cassette component and YhbN is the putative periplasmic-binding protein. Depletion of each gene product leads to growth arrest, irreversible cell damage and loss of viability in E. coli. The YhbG homolog (NtrA) is essential in Rhizobium meliloti, a symbiotic nitrogen-fixing bacterium.
Pssm-ID: 213185 [Multi-domain] Cd Length: 232 Bit Score: 53.70 E-value: 7.85e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 344 ITKPISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITFG------------ANLQIGYYDQKQAEFKSsktil 411
Cdd:cd03218 15 VVNGVSLSVKQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGKILLDgqditklpmhkrARLGIGYLPQEASIFRK----- 89
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446524717 412 dyvwdqypLMNEKDIRAVLGRFLFVQDDVKKIIND-----------------LSGGEKARLQLALLMLQRDNVLILDEP 473
Cdd:cd03218 90 --------LTVEENILAVLEIRGLSKKEREEKLEElleefhithlrkskassLSGGERRRVEIARALATNPKFLLLDEP 160
|
|
| PRK11000 |
PRK11000 |
maltose/maltodextrin ABC transporter ATP-binding protein MalK; |
1-58 |
8.46e-08 |
|
maltose/maltodextrin ABC transporter ATP-binding protein MalK;
Pssm-ID: 182893 [Multi-domain] Cd Length: 369 Bit Score: 54.65 E-value: 8.46e-08
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 446524717 1 MILLQLNHISKSFDGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSG 58
Cdd:PRK11000 1 MASVTLRNVTKAYGDVVISKDINLDIHEGEFVVFVGPSGCGKSTLLRMIAGLEDITSG 58
|
|
| nickel_nikE |
TIGR02769 |
nickel import ATP-binding protein NikE; This family represents the NikE subunit of a ... |
330-523 |
8.57e-08 |
|
nickel import ATP-binding protein NikE; This family represents the NikE subunit of a multisubunit nickel import ABC transporter complex. Nickel, once imported, may be used in urease and in certain classes of hydrogenase and superoxide dismutase. [Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 131816 [Multi-domain] Cd Length: 265 Bit Score: 54.04 E-value: 8.57e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 330 VMHVKNLEIGYQT----------AITKPISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITF-GANLqigyYD 398
Cdd:TIGR02769 2 LLEVRDVTHTYRTgglfgakqraPVLTNVSLSIEEGETVGLLGRSGCGKSTLARLLLGLEKPAQGTVSFrGQDL----YQ 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 399 QKQAEFKSSKTILDYVW-DQYPLMN-EKDIRAVLGRFL-----------------------FVQDDVKKIINDLSGGEKA 453
Cdd:TIGR02769 78 LDRKQRRAFRRDVQLVFqDSPSAVNpRMTVRQIIGEPLrhltsldeseqkariaelldmvgLRSEDADKLPRQLSGGQLQ 157
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446524717 454 RLQLALLMLQRDNVLILDEPTNHLDIDSK----EMLEQALQHFEGTILFVSHDRYFINQLANKVfdLTIDGGKM 523
Cdd:TIGR02769 158 RINIARALAVKPKLIVLDEAVSNLDMVLQavilELLRKLQQAFGTAYLFITHDLRLVQSFCQRV--AVMDKGQI 229
|
|
| PhnC |
COG3638 |
ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and ... |
3-230 |
9.29e-08 |
|
ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 442855 [Multi-domain] Cd Length: 249 Bit Score: 53.52 E-value: 9.29e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 3 LLQLNHISKSFDGED-IFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNVS----KIKNLK---------- 67
Cdd:COG3638 2 MLELRNLSKRYPGGTpALDDVSLEIERGEFVALIGPSGAGKSTLLRCLNGLVEPTSGEILvdgqDVTALRgralrrlrrr 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 68 LGYLTQQMTLNSNATVFEEMskpfehikrmeslikeetdwLSKHANdydsdtyktHMSRYESLSNQF---EQLEGYQYes 144
Cdd:COG3638 82 IGMIFQQFNLVPRLSVLTNV--------------------LAGRLG---------RTSTWRSLLGLFppeDRERALEA-- 130
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 145 kIKTVlhGLnfseEDF-NKPINDFSGGQKTRLSLAQMLLNEPDLLLLDEPTNHLDLETTkwlEDYLRYFK------GAIV 217
Cdd:COG3638 131 -LERV--GL----ADKaYQRADQLSGGQQQRVAIARALVQEPKLILADEPVASLDPKTA---RQVMDLLRriaredGITV 200
|
250
....*....|....*....
gi 446524717 218 IIS-HD-----RYFlDKIV 230
Cdd:COG3638 201 VVNlHQvdlarRYA-DRII 218
|
|
| 3a01204 |
TIGR00955 |
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, ... |
344-516 |
1.22e-07 |
|
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273361 [Multi-domain] Cd Length: 617 Bit Score: 54.67 E-value: 1.22e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 344 ITKPISIEVSKGDHIAIIGPNGIGKSTLIKTIAN----------------------QQKALNGYI--------------- 386
Cdd:TIGR00955 40 LLKNVSGVAKPGELLAVMGSSGAGKTTLMNALAFrspkgvkgsgsvllngmpidakEMRAISAYVqqddlfiptltvreh 119
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 387 -TFGANLQIG---YYDQKQAefkssktILDYVWDQYPLMNEKDIRavLGrflfVQDDVKkiinDLSGGEKARLQLALLML 462
Cdd:TIGR00955 120 lMFQAHLRMPrrvTKKEKRE-------RVDEVLQALGLRKCANTR--IG----VPGRVK----GLSGGERKRLAFASELL 182
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 446524717 463 QRDNVLILDEPTNHLDIDSKEMLEQALQHF--EGTILFVShdryfINQLANKVFDL 516
Cdd:TIGR00955 183 TDPPLLFCDEPTSGLDSFMAYSVVQVLKGLaqKGKTIICT-----IHQPSSELFEL 233
|
|
| ABC_ModC_like |
cd03299 |
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely ... |
4-222 |
1.35e-07 |
|
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely related to ModC. ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213266 [Multi-domain] Cd Length: 235 Bit Score: 52.72 E-value: 1.35e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 4 LQLNHISKSFdGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNVS----KIKNLK-----LGYLTQQ 74
Cdd:cd03299 1 LKVENLSKDW-KEFKLKNVSLEVERGDYFVILGPTGSGKSVLLETIAGFIKPDSGKILlngkDITNLPpekrdISYVPQN 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 75 MTLNSNATVFEEMSKPFEHIKRMESLIKEETDWLSKHANdydsdtykthmsryeslsnqfeqlegyqyeskIKTVLHgln 154
Cdd:cd03299 80 YALFPHMTVYKNIAYGLKKRKVDKKEIERKVLEIAEMLG--------------------------------IDHLLN--- 124
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446524717 155 fseedfNKPINdFSGGQKTRLSLAQMLLNEPDLLLLDEPTNHLDLETT----KWLEDYLRYFKGAIVIISHD 222
Cdd:cd03299 125 ------RKPET-LSGGEQQRVAIARALVVNPKILLLDEPFSALDVRTKeklrEELKKIRKEFGVTVLHVTHD 189
|
|
| nikE |
PRK10419 |
nickel ABC transporter ATP-binding protein NikE; |
1-61 |
1.36e-07 |
|
nickel ABC transporter ATP-binding protein NikE;
Pssm-ID: 236689 [Multi-domain] Cd Length: 268 Bit Score: 53.15 E-value: 1.36e-07
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 1 MILLQLNHISKSFDGEDIFT---------DVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNVS 61
Cdd:PRK10419 1 MTLLNVSGLSHHYAHGGLSGkhqhqtvlnNVSLSLKSGETVALLGRSGCGKSTLARLLVGLESPSQGNVS 70
|
|
| PRK13409 |
PRK13409 |
ribosome biogenesis/translation initiation ATPase RLI; |
352-502 |
1.58e-07 |
|
ribosome biogenesis/translation initiation ATPase RLI;
Pssm-ID: 184037 [Multi-domain] Cd Length: 590 Bit Score: 54.43 E-value: 1.58e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 352 VSKGDHIAIIGPNGIGKSTLIKTIANQQKA-LNGYIT----------F-GANLQIGYYDQKQAEFKSSKTIlDYVwDQYP 419
Cdd:PRK13409 96 PKEGKVTGILGPNGIGKTTAVKILSGELIPnLGDYEEepswdevlkrFrGTELQNYFKKLYNGEIKVVHKP-QYV-DLIP 173
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 420 ---------LMNEKDIRAVLgrflfvqDDVKKI----------INDLSGGEKARLQLALLMLQRDNVLILDEPTNHLDID 480
Cdd:PRK13409 174 kvfkgkvreLLKKVDERGKL-------DEVVERlglenildrdISELSGGELQRVAIAAALLRDADFYFFDEPTSYLDIR 246
|
170 180
....*....|....*....|....
gi 446524717 481 SKEMLEQALQHF--EGTILFVSHD 502
Cdd:PRK13409 247 QRLNVARLIRELaeGKYVLVVEHD 270
|
|
| cbiO |
PRK13648 |
cobalt transporter ATP-binding subunit; Provisional |
325-502 |
1.62e-07 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184207 [Multi-domain] Cd Length: 269 Bit Score: 53.22 E-value: 1.62e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 325 NTGNDVMHVKNLEIGYQ--TAIT-KPISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITF------GANLQ-- 393
Cdd:PRK13648 2 EDKNSIIVFKNVSFQYQsdASFTlKDVSFNIPKGQWTSIVGHNGSGKSTIAKLMIGIEKVKSGEIFYnnqaitDDNFEkl 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 394 ---IGYYDQK-QAEFKSSktILDYvwdqyplmnekDIRAVLGRFLFVQDDVKKIIND-----------------LSGGEK 452
Cdd:PRK13648 82 rkhIGIVFQNpDNQFVGS--IVKY-----------DVAFGLENHAVPYDEMHRRVSEalkqvdmleradyepnaLSGGQK 148
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 446524717 453 ARLQLALLMLQRDNVLILDEPTNHLDIDSKEMLEQALQHFEG----TILFVSHD 502
Cdd:PRK13648 149 QRVAIAGVLALNPSVIILDEATSMLDPDARQNLLDLVRKVKSehniTIISITHD 202
|
|
| ABC_MalK_N |
cd03301 |
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) ... |
339-502 |
1.71e-07 |
|
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) proteins function from bacteria to human, mediating the translocation of substances into and out of cells or organelles. ABC transporters contain two transmembrane-spanning domains (TMDs) or subunits and two nucleotide binding domains (NBDs) or subunits that couple transport to the hydrolysis of ATP. In the maltose transport system, the periplasmic maltose binding protein (MBP) stimulates the ATPase activity of the membrane-associated transporter, which consists of two transmembrane subunits, MalF and MalG, and two copies of the ATP binding subunit, MalK, and becomes tightly bound to the transporter in the catalytic transition state, ensuring that maltose is passed to the transporter as ATP is hydrolyzed.
Pssm-ID: 213268 [Multi-domain] Cd Length: 213 Bit Score: 52.26 E-value: 1.71e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 339 GYQTAItKPISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITFGanlqigyyDQKQAEFKSSKTILDYVWDQ- 417
Cdd:cd03301 11 GNVTAL-DDLNLDIADGEFVVLLGPSGCGKTTTLRMIAGLEEPTSGRIYIG--------GRDVTDLPPKDRDIAMVFQNy 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 418 --YPLMNEKD-IRAVLGRFLFVQDDVKKIIND-----------------LSGGEKARLQLALLMLQRDNVLILDEPTNHL 477
Cdd:cd03301 82 alYPHMTVYDnIAFGLKLRKVPKDEIDERVREvaellqiehlldrkpkqLSGGQRQRVALGRAIVREPKVFLMDEPLSNL 161
|
170 180
....*....|....*....|....*....
gi 446524717 478 D----IDSKEMLEQALQHFEGTILFVSHD 502
Cdd:cd03301 162 DaklrVQMRAELKRLQQRLGTTTIYVTHD 190
|
|
| 3a01208 |
TIGR00958 |
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other] |
344-514 |
1.73e-07 |
|
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273363 [Multi-domain] Cd Length: 711 Bit Score: 54.34 E-value: 1.73e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 344 ITKPISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITF-GANL----------QIGYYDQKQAEFKSS-KTIL 411
Cdd:TIGR00958 496 VLKGLTFTLHPGEVVALVGPSGSGKSTVAALLQNLYQPTGGQVLLdGVPLvqydhhylhrQVALVGQEPVLFSGSvRENI 575
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 412 DYVWDQYPlmnEKDIRAVlGRFLFVQDDVKKIIND-----------LSGGEKARLQLALLMLQRDNVLILDEPTNHLDID 480
Cdd:TIGR00958 576 AYGLTDTP---DEEIMAA-AKAANAHDFIMEFPNGydtevgekgsqLSGGQKQRIAIARALVRKPRVLILDEATSALDAE 651
|
170 180 190
....*....|....*....|....*....|....
gi 446524717 481 SKEMLEQALQHFEGTILFVSHdRYFINQLANKVF 514
Cdd:TIGR00958 652 CEQLLQESRSRASRTVLLIAH-RLSTVERADQIL 684
|
|
| ugpC |
PRK11650 |
sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC; |
1-61 |
1.79e-07 |
|
sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;
Pssm-ID: 236947 [Multi-domain] Cd Length: 356 Bit Score: 53.69 E-value: 1.79e-07
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446524717 1 MILLQLNHISKSFDGE-DIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNVS 61
Cdd:PRK11650 1 MAGLKLQAVRKSYDGKtQVIKGIDLDVADGEFIVLVGPSGCGKSTLLRMVAGLERITSGEIW 62
|
|
| PRK10895 |
PRK10895 |
lipopolysaccharide ABC transporter ATP-binding protein; Provisional |
1-87 |
1.93e-07 |
|
lipopolysaccharide ABC transporter ATP-binding protein; Provisional
Pssm-ID: 182817 [Multi-domain] Cd Length: 241 Bit Score: 52.59 E-value: 1.93e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 1 MILLQLNHISKSFDGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNV----SKIKNLKL-------- 68
Cdd:PRK10895 1 MATLTAKNLAKAYKGRRVVEDVSLTVNSGEIVGLLGPNGAGKTTTFYMVVGIVPRDAGNIiiddEDISLLPLhararrgi 80
|
90
....*....|....*....
gi 446524717 69 GYLTQQMTLNSNATVFEEM 87
Cdd:PRK10895 81 GYLPQEASIFRRLSVYDNL 99
|
|
| ABC_RNaseL_inhibitor_domain2 |
cd03237 |
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ... |
25-227 |
1.96e-07 |
|
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity of more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.
Pssm-ID: 213204 [Multi-domain] Cd Length: 246 Bit Score: 52.41 E-value: 1.96e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 25 EVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNVsKIKNLKLGYLTQQMTLNSNATVFEEMSkpfehikrmeslikee 104
Cdd:cd03237 21 SISESEVIGILGPNGIGKTTFIKMLAGVLKPDEGDI-EIELDTVSYKPQYIKADYEGTVRDLLS---------------- 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 105 tdwlSKHANDYDSDTYKTHMSRyeslSNQFEQLegyqYESKIktvlhglnfseedfnkpiNDFSGGQKTRLSLAQMLLNE 184
Cdd:cd03237 84 ----SITKDFYTHPYFKTEIAK----PLQIEQI----LDREV------------------PELSGGELQRVAIAACLSKD 133
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 446524717 185 PDLLLLDEPTNHLDLE----TTKWLEDYLRYFKGAIVIISHDRYFLD 227
Cdd:cd03237 134 ADIYLLDEPSAYLDVEqrlmASKVIRRFAENNEKTAFVVEHDIIMID 180
|
|
| type_I_sec_LssB |
TIGR03375 |
type I secretion system ATPase, LssB family; Type I protein secretion is a system in some ... |
21-233 |
2.17e-07 |
|
type I secretion system ATPase, LssB family; Type I protein secretion is a system in some Gram-negative bacteria to export proteins (often proteases) across both inner and outer membranes to the extracellular medium. This is one of three proteins of the type I secretion apparatus. Targeted proteins are not cleaved at the N-terminus, but rather carry signals located toward the extreme C-terminus to direct type I secretion. This model is related to models TIGR01842 and TIGR01846, and to bacteriocin ABC transporters that cleave their substrates during export. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis]
Pssm-ID: 274550 [Multi-domain] Cd Length: 694 Bit Score: 54.10 E-value: 2.17e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 21 DVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNVS----KIKNL-------KLGYLTQQMTLNSnATVFE--EM 87
Cdd:TIGR03375 483 NVSLTIRPGEKVAIIGRIGSGKSTLLKLLLGLYQPTEGSVLldgvDIRQIdpadlrrNIGYVPQDPRLFY-GTLRDniAL 561
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 88 SKPF---EHIkrMESLIKEE-TDWLSKHANDYDsdtyktHM--SRYESLSnqfeqlegyqyeskiktvlhglnfseedfn 161
Cdd:TIGR03375 562 GAPYaddEEI--LRAAELAGvTEFVRRHPDGLD------MQigERGRSLS------------------------------ 603
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446524717 162 kpindfsGGQKTRLSLAQMLLNEPDLLLLDEPTNHLDLETTKWLEDYLRYFKG--AIVIISHDRYFLDkIVTQI 233
Cdd:TIGR03375 604 -------GGQRQAVALARALLRDPPILLLDEPTSAMDNRSEERFKDRLKRWLAgkTLVLVTHRTSLLD-LVDRI 669
|
|
| SufC |
COG0396 |
Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, ... |
333-501 |
2.37e-07 |
|
Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440165 [Multi-domain] Cd Length: 245 Bit Score: 52.38 E-value: 2.37e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 333 VKNL--EIGyQTAITKPISIEVSKGDHIAIIGPNGIGKSTLIKTIAN--QQKALNGYITFG------------ANLQIGY 396
Cdd:COG0396 3 IKNLhvSVE-GKEILKGVNLTIKPGEVHAIMGPNGSGKSTLAKVLMGhpKYEVTSGSILLDgedilelspderARAGIFL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 397 YDQKQAEFK----SS--KTILDYVWDQYPLMNE--KDIRAVLGRFLFVQDDVKKIIND-LSGGEKARLQLALLMLQRDNV 467
Cdd:COG0396 82 AFQYPVEIPgvsvSNflRTALNARRGEELSAREflKLLKEKMKELGLDEDFLDRYVNEgFSGGEKKRNEILQMLLLEPKL 161
|
170 180 190
....*....|....*....|....*....|....*..
gi 446524717 468 LILDEPTNHLDIDSKEMLEQALQHF---EGTILFVSH 501
Cdd:COG0396 162 AILDETDSGLDIDALRIVAEGVNKLrspDRGILIITH 198
|
|
| PRK13657 |
PRK13657 |
glucan ABC transporter ATP-binding protein/ permease; |
3-86 |
2.51e-07 |
|
glucan ABC transporter ATP-binding protein/ permease;
Pssm-ID: 184214 [Multi-domain] Cd Length: 588 Bit Score: 53.81 E-value: 2.51e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 3 LLQLNHISKSFDGE-DIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNVsKIKNLKLGYLTQQMTLNSNA 81
Cdd:PRK13657 334 AVEFDDVSFSYDNSrQGVEDVSFEAKPGQTVAIVGPTGAGKSTLINLLQRVFDPQSGRI-LIDGTDIRTVTRASLRRNIA 412
|
....*
gi 446524717 82 TVFEE 86
Cdd:PRK13657 413 VVFQD 417
|
|
| potG |
PRK11607 |
putrescine ABC transporter ATP-binding subunit PotG; |
3-223 |
2.71e-07 |
|
putrescine ABC transporter ATP-binding subunit PotG;
Pssm-ID: 183226 [Multi-domain] Cd Length: 377 Bit Score: 53.30 E-value: 2.71e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 3 LLQLNHISKSFDGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGnvskiknlklgyltqQMTLNSnat 82
Cdd:PRK11607 19 LLEIRNLTKSFDGQHAVDDVSLTIYKGEIFALLGASGCGKSTLLRMLAGFEQPTAG---------------QIMLDG--- 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 83 vfEEMSK--PFEH-IKRMeslikeetdwlskhandYDSDTYKTHMSRYESLSNQFEQ--LEGYQYESKIKTVLHGLNFSE 157
Cdd:PRK11607 81 --VDLSHvpPYQRpINMM-----------------FQSYALFPHMTVEQNIAFGLKQdkLPKAEIASRVNEMLGLVHMQE 141
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 158 EDFNKPiNDFSGGQKTRLSLAQMLLNEPDLLLLDEPTNHLD--LETTKWLE--DYLRYFKGAIVIISHDR 223
Cdd:PRK11607 142 FAKRKP-HQLSGGQRQRVALARSLAKRPKLLLLDEPMGALDkkLRDRMQLEvvDILERVGVTCVMVTHDQ 210
|
|
| PRK13543 |
PRK13543 |
heme ABC exporter ATP-binding protein CcmA; |
3-200 |
3.64e-07 |
|
heme ABC exporter ATP-binding protein CcmA;
Pssm-ID: 184129 [Multi-domain] Cd Length: 214 Bit Score: 51.39 E-value: 3.64e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 3 LLQLNHISKSFDGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGnvskiknlklgyltqQMTLNSNAT 82
Cdd:PRK13543 11 LLAAHALAFSRNEEPVFGPLDFHVDAGEALLVQGDNGAGKTTLLRVLAGLLHVESG---------------QIQIDGKTA 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 83 VFEEMSKPFEHIKRMESLikeetdwlskhandydsdtyKTHMSRYESLsNQFEQLEGYQYESKIKTVLH--GLNFSEEDF 160
Cdd:PRK13543 76 TRGDRSRFMAYLGHLPGL--------------------KADLSTLENL-HFLCGLHGRRAKQMPGSALAivGLAGYEDTL 134
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 446524717 161 nkpINDFSGGQKTRLSLAQMLLNEPDLLLLDEPTNHLDLE 200
Cdd:PRK13543 135 ---VRQLSAGQKKRLALARLWLSPAPLWLLDEPYANLDLE 171
|
|
| DppD |
COG0444 |
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ... |
3-51 |
3.68e-07 |
|
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];
Pssm-ID: 440213 [Multi-domain] Cd Length: 320 Bit Score: 52.36 E-value: 3.68e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 446524717 3 LLQLNHISKSFDGEDIFT----DVDFEVKTGERIGIVGRNGAGKSTLMKIIAG 51
Cdd:COG0444 1 LLEVRNLKVYFPTRRGVVkavdGVSFDVRRGETLGLVGESGSGKSTLARAILG 53
|
|
| PRK10247 |
PRK10247 |
putative ABC transporter ATP-binding protein YbbL; Provisional |
2-223 |
4.30e-07 |
|
putative ABC transporter ATP-binding protein YbbL; Provisional
Pssm-ID: 182331 [Multi-domain] Cd Length: 225 Bit Score: 51.25 E-value: 4.30e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 2 ILLQLNHISKSFDGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNV----SKIKNLK-------LGY 70
Cdd:PRK10247 6 PLLQLQNVGYLAGDAKILNNISFSLRAGEFKLITGPSGCGKSTLLKIVASLISPTSGTLlfegEDISTLKpeiyrqqVSY 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 71 LTQQMTLNSNaTVFEEMSKPFEhikrmeslIKEETDWLSKHANDYDsdtykthmsryeslsnQFEqlegyqyeskiktvl 150
Cdd:PRK10247 86 CAQTPTLFGD-TVYDNLIFPWQ--------IRNQQPDPAIFLDDLE----------------RFA--------------- 125
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446524717 151 hglnFSEEDFNKPINDFSGGQKTRLSLAQMLLNEPDLLLLDEPTNHLDLETTKWLED----YLRYFKGAIVIISHDR 223
Cdd:PRK10247 126 ----LPDTILTKNIAELSGGEKQRISLIRNLQFMPKVLLLDEITSALDESNKHNVNEiihrYVREQNIAVLWVTHDK 198
|
|
| ABCC_NFT1 |
cd03369 |
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type ... |
14-221 |
4.51e-07 |
|
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type transporter 1). NFT1 belongs to the MRP (multidrug resistance-associated protein) family of ABC transporters. Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213269 [Multi-domain] Cd Length: 207 Bit Score: 50.87 E-value: 4.51e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 14 DGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNVsKIKNLKLGYLtqqmtlnsnatvfeemskPFEH 93
Cdd:cd03369 19 DLPPVLKNVSFKVKAGEKIGIVGRTGAGKSTLILALFRFLEAEEGKI-EIDGIDISTI------------------PLED 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 94 IKRMESLIKEETDWLskhandydSDTYKTHMSRYESLSnqfeqlegyqyESKIKTVLH----GLNFSEedfnkpindfsg 169
Cdd:cd03369 80 LRSSLTIIPQDPTLF--------SGTIRSNLDPFDEYS-----------DEEIYGALRvsegGLNLSQ------------ 128
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 446524717 170 GQKTRLSLAQMLLNEPDLLLLDEPTNHLDLETTKWLEDYLR-YFKGA-IVIISH 221
Cdd:cd03369 129 GQRQLLCLARALLKRPRVLVLDEATASIDYATDALIQKTIReEFTNStILTIAH 182
|
|
| ABCC_ATM1_transporter |
cd03253 |
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC ... |
334-501 |
4.64e-07 |
|
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC transporter that is expressed in the mitochondria. Although the specific function of ATM1 is unknown, its disruption results in the accumulation of excess mitochondrial iron, loss of mitochondrial cytochromes, oxidative damage to mitochondrial DNA, and decreased levels of cytosolic heme proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213220 [Multi-domain] Cd Length: 236 Bit Score: 51.46 E-value: 4.64e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 334 KNLEIGYQTA--ITKPISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITF-GANL----------QIGYYDQK 400
Cdd:cd03253 4 ENVTFAYDPGrpVLKDVSFTIPAGKKVAIVGPSGSGKSTILRLLFRFYDVSSGSILIdGQDIrevtldslrrAIGVVPQD 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 401 QAEFKSskTILDYVwdQY--PLMNEKDIRAVlGRFLFVQDDVKKIIND-----------LSGGEKARLQLALLMLQRDNV 467
Cdd:cd03253 84 TVLFND--TIGYNI--RYgrPDATDEEVIEA-AKAAQIHDKIMRFPDGydtivgerglkLSGGEKQRVAIARAILKNPPI 158
|
170 180 190
....*....|....*....|....*....|....*.
gi 446524717 468 LILDEPTNHLDIDSKEMLEQALQH-FEG-TILFVSH 501
Cdd:cd03253 159 LLLDEATSALDTHTEREIQAALRDvSKGrTTIVIAH 194
|
|
| ABCC_Hemolysin |
cd03252 |
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a ... |
348-523 |
4.81e-07 |
|
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a central component of the secretion machinery that translocates the toxin, hemolysin A, in a Sec-independent fashion across both membranes of E. coli. The hemolysin A (HlyA) transport machinery is composed of the ATP-binding cassette (ABC) transporter HlyB located in the inner membrane, hemolysin D (HlyD), also anchored in the inner membrane, and TolC, which resides in the outer membrane. HlyD apparently forms a continuous channel that bridges the entire periplasm, interacting with TolC and HlyB. This arrangement prevents the appearance of periplasmic intermediates of HlyA during substrate transport. Little is known about the molecular details of HlyA transport, but it is evident that ATP-hydrolysis by the ABC-transporter HlyB is a necessary source of energy.
Pssm-ID: 213219 [Multi-domain] Cd Length: 237 Bit Score: 51.33 E-value: 4.81e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 348 ISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITF-GANL----------QIGYYDQKQAEFksSKTILDYVWD 416
Cdd:cd03252 21 ISLRIKPGEVVGIVGRSGSGKSTLTKLIQRFYVPENGRVLVdGHDLaladpawlrrQVGVVLQENVLF--NRSIRDNIAL 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 417 QYPLMNEKDIRAVlGRFLFVQDDVKK-------IIND----LSGGEKARLQLALLMLQRDNVLILDEPTNHLDIDSKEML 485
Cdd:cd03252 99 ADPGMSMERVIEA-AKLAGAHDFISElpegydtIVGEqgagLSGGQRQRIAIARALIHNPRILIFDEATSALDYESEHAI 177
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 446524717 486 EQALQHFEG--TILFVSHdRYFINQLANKVfdLTIDGGKM 523
Cdd:cd03252 178 MRNMHDICAgrTVIIIAH-RLSTVKNADRI--IVMEKGRI 214
|
|
| cbiO |
PRK13647 |
cobalt transporter ATP-binding subunit; Provisional |
328-543 |
5.06e-07 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237457 [Multi-domain] Cd Length: 274 Bit Score: 51.66 E-value: 5.06e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 328 NDVMHVKNLEIGYQ--TAITKPISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYIT-FGANL----------QI 394
Cdd:PRK13647 2 DNIIEVEDLHFRYKdgTKALKGLSLSIPEGSKTALLGPNGAGKSTLLLHLNGIYLPQRGRVKvMGREVnaenekwvrsKV 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 395 G--YYDQKQAEFKSSktildyVWDQY---PLMNEKDIRAVLGR------FLFVQDDVKKIINDLSGGEKARLQLALLMLQ 463
Cdd:PRK13647 82 GlvFQDPDDQVFSST------VWDDVafgPVNMGLDKDEVERRveealkAVRMWDFRDKPPYHLSYGQKKRVAIAGVLAM 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 464 RDNVLILDEPTNHLDIDSKEMLEQALQ--HFEG-TILFVSHDRYFINQLANKVFDLT-----IDGGKMYLGDyqyyiEKV 535
Cdd:PRK13647 156 DPDVIVLDEPMAYLDPRGQETLMEILDrlHNQGkTVIVATHDVDLAAEWADQVIVLKegrvlAEGDKSLLTD-----EDI 230
|
....*...
gi 446524717 536 EEAEALKA 543
Cdd:PRK13647 231 VEQAGLRL 238
|
|
| PRK09984 |
PRK09984 |
phosphonate ABC transporter ATP-binding protein; |
3-210 |
5.14e-07 |
|
phosphonate ABC transporter ATP-binding protein;
Pssm-ID: 182182 [Multi-domain] Cd Length: 262 Bit Score: 51.55 E-value: 5.14e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 3 LLQLNHISKSFDGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNVSKIKNL---------------- 66
Cdd:PRK09984 4 IIRVEKLAKTFNQHQALHAVDLNIHHGEMVALLGPSGSGKSTLLRHLSGLITGDKSAGSHIELLgrtvqregrlardirk 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 67 ---KLGYLTQQMTLNSNATVFEEM------SKPFehikrmeslikeetdwlskhandydsdtYKTHMSRYESLSNQfeql 137
Cdd:PRK09984 84 sraNTGYIFQQFNLVNRLSVLENVligalgSTPF----------------------------WRTCFSWFTREQKQ---- 131
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446524717 138 EGYQYESKIKTVlhglNFSEEDfnkpINDFSGGQKTRLSLAQMLLNEPDLLLLDEPTNHLDLETTKWLEDYLR 210
Cdd:PRK09984 132 RALQALTRVGMV----HFAHQR----VSTLSGGQQQRVAIARALMQQAKVILADEPIASLDPESARIVMDTLR 196
|
|
| PRK14271 |
PRK14271 |
phosphate ABC transporter ATP-binding protein; Provisional |
323-502 |
6.35e-07 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172759 [Multi-domain] Cd Length: 276 Bit Score: 51.25 E-value: 6.35e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 323 DRNTGNDVMHVKNLEIGYQ-TAITKPISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGY-----ITFGANLQIGY 396
Cdd:PRK14271 14 DVDAAAPAMAAVNLTLGFAgKTVLDQVSMGFPARAVTSLMGPTGSGKTTFLRTLNRMNDKVSGYrysgdVLLGGRSIFNY 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 397 YD------------QKQAEFKSSktILDYVW---DQYPLMNEKDIRAVLGRFLF---VQDDVKKIIND----LSGGEKAR 454
Cdd:PRK14271 94 RDvlefrrrvgmlfQRPNPFPMS--IMDNVLagvRAHKLVPRKEFRGVAQARLTevgLWDAVKDRLSDspfrLSGGQQQL 171
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 446524717 455 LQLALLMLQRDNVLILDEPTNHLDIDSKEMLEQALQHFEG--TILFVSHD 502
Cdd:PRK14271 172 LCLARTLAVNPEVLLLDEPTSALDPTTTEKIEEFIRSLADrlTVIIVTHN 221
|
|
| ABCC_MRP_domain2 |
cd03244 |
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C ... |
21-46 |
6.37e-07 |
|
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resistance lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213211 [Multi-domain] Cd Length: 221 Bit Score: 50.57 E-value: 6.37e-07
10 20
....*....|....*....|....*.
gi 446524717 21 DVDFEVKTGERIGIVGRNGAGKSTLM 46
Cdd:cd03244 22 NISFSIKPGEKVGIVGRTGSGKSSLL 47
|
|
| PRK13657 |
PRK13657 |
glucan ABC transporter ATP-binding protein/ permease; |
348-489 |
6.65e-07 |
|
glucan ABC transporter ATP-binding protein/ permease;
Pssm-ID: 184214 [Multi-domain] Cd Length: 588 Bit Score: 52.27 E-value: 6.65e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 348 ISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITF-GANL----------QIGYYDQKQAEFksSKTILDYVWD 416
Cdd:PRK13657 354 VSFEAKPGQTVAIVGPTGAGKSTLINLLQRVFDPQSGRILIdGTDIrtvtraslrrNIAVVFQDAGLF--NRSIEDNIRV 431
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 417 QYPLMNEKDIRAVLGR-----FLFVQDD-----VKKIINDLSGGEKARLQLALLMLQRDNVLILDEPTNHLDIDSKEMLE 486
Cdd:PRK13657 432 GRPDATDEEMRAAAERaqahdFIERKPDgydtvVGERGRQLSGGERQRLAIARALLKDPPILILDEATSALDVETEAKVK 511
|
...
gi 446524717 487 QAL 489
Cdd:PRK13657 512 AAL 514
|
|
| PRK13651 |
PRK13651 |
cobalt transporter ATP-binding subunit; Provisional |
329-502 |
8.20e-07 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184210 [Multi-domain] Cd Length: 305 Bit Score: 51.24 E-value: 8.20e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 329 DVMHVKNLEIGYQTAITKPISIEVSKGDHIAIIGPNGIGKSTLIKtianqqkALNGYITFGA-NLQIGYYDQKQAefKSS 407
Cdd:PRK13651 7 NIVKIFNKKLPTELKALDNVSVEINQGEFIAIIGQTGSGKTTFIE-------HLNALLLPDTgTIEWIFKDEKNK--KKT 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 408 KTILDYVWD---QYP----LMNEKDIRAVLG---RF----LF---VQDDV------------------KKIIN------- 445
Cdd:PRK13651 78 KEKEKVLEKlviQKTrfkkIKKIKEIRRRVGvvfQFaeyqLFeqtIEKDIifgpvsmgvskeeakkraAKYIElvgldes 157
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446524717 446 -------DLSGGEKARLQLALLMLQRDNVLILDEPTNHLD-IDSKEMLE--QALQHFEGTILFVSHD 502
Cdd:PRK13651 158 ylqrspfELSGGQKRRVALAGILAMEPDFLVFDEPTAGLDpQGVKEILEifDNLNKQGKTIILVTHD 224
|
|
| ArtP |
COG4161 |
ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism]; |
4-233 |
8.26e-07 |
|
ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443326 [Multi-domain] Cd Length: 242 Bit Score: 50.78 E-value: 8.26e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 4 LQLNHISKSFDGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSG---------------NVSKIKNL-- 66
Cdd:COG4161 3 IQLKNINCFYGSHQALFDINLECPSGETLVLLGPSGAGKSSLLRVLNLLETPDSGqlniaghqfdfsqkpSEKAIRLLrq 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 67 KLGYLTQQMTLnsnatvfeemskpFEHIKRMESLIkEETDWLSKhandydsdtykthMSRYESLSNQFEQLEGYQYESKI 146
Cdd:COG4161 83 KVGMVFQQYNL-------------WPHLTVMENLI-EAPCKVLG-------------LSKEQAREKAMKLLARLRLTDKA 135
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 147 KTV-LHglnfseedfnkpindFSGGQKTRLSLAQMLLNEPDLLLLDEPTNHLDLETTKWLEDYLRYFKG-AI--VIISHD 222
Cdd:COG4161 136 DRFpLH---------------LSGGQQQRVAIARALMMEPQVLLFDEPTAALDPEITAQVVEIIRELSQtGItqVIVTHE 200
|
250
....*....|.
gi 446524717 223 RYFLDKIVTQI 233
Cdd:COG4161 201 VEFARKVASQV 211
|
|
| PRK14267 |
PRK14267 |
phosphate ABC transporter ATP-binding protein; Provisional |
328-501 |
8.46e-07 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 184596 [Multi-domain] Cd Length: 253 Bit Score: 50.61 E-value: 8.46e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 328 NDVMHVKNLEIGY-QTAITKPISIEVSKGDHIAIIGPNGIGKSTLIKTI-----ANQQKALNGYIT-FGANL-------- 392
Cdd:PRK14267 2 KFAIETVNLRVYYgSNHVIKGVDLKIPQNGVFALMGPSGCGKSTLLRTFnrlleLNEEARVEGEVRlFGRNIyspdvdpi 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 393 ----QIGYYDQKQAEFkSSKTILDYVWDQYPLMN----EKDIRAVLGRFL---FVQDDVKKIIND----LSGGEKARLQL 457
Cdd:PRK14267 82 evrrEVGMVFQYPNPF-PHLTIYDNVAIGVKLNGlvksKKELDERVEWALkkaALWDEVKDRLNDypsnLSGGQRQRLVI 160
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 446524717 458 ALLMLQRDNVLILDEPTNHLDIDSKEMLEQALQHF--EGTILFVSH 501
Cdd:PRK14267 161 ARALAMKPKILLMDEPTANIDPVGTAKIEELLFELkkEYTIVLVTH 206
|
|
| ABCD_peroxisomal_ALDP |
cd03223 |
ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding ... |
4-74 |
9.25e-07 |
|
ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding cassette transporter (Pat) is involved in the import of very long-chain fatty acids (VLCFA) into the peroxisome. The peroxisomal membrane forms a permeability barrier for a wide variety of metabolites required for and formed during fatty acid beta-oxidation. To communicate with the cytoplasm and mitochondria, peroxisomes need dedicated proteins to transport such hydrophilic molecules across their membranes. X-linked adrenoleukodystrophy (X-ALD) is caused by mutations in the ALD gene, which encodes ALDP (adrenoleukodystrophy protein ), a peroxisomal integral membrane protein that is a member of the ATP-binding cassette (ABC) transporter protein family. The disease is characterized by a striking and unpredictable variation in phenotypic expression. Phenotypes include the rapidly progressive childhood cerebral form (CCALD), the milder adult form, adrenomyeloneuropathy (AMN), and variants without neurologic involvement (i.e. asymptomatic).
Pssm-ID: 213190 [Multi-domain] Cd Length: 166 Bit Score: 49.07 E-value: 9.25e-07
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446524717 4 LQLNHIS-KSFDGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNVSKIKNLKLGYLTQQ 74
Cdd:cd03223 1 IELENLSlATPDGRVLLKDLSFEIKPGDRLLITGPSGTGKSSLFRALAGLWPWGSGRIGMPEGEDLLFLPQR 72
|
|
| cbiO |
PRK13648 |
cobalt transporter ATP-binding subunit; Provisional |
3-222 |
9.96e-07 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184207 [Multi-domain] Cd Length: 269 Bit Score: 50.52 E-value: 9.96e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 3 LLQLNHISKSFDGEDIFT--DVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNVskiknlklgYLTQQMTLNSN 80
Cdd:PRK13648 7 IIVFKNVSFQYQSDASFTlkDVSFNIPKGQWTSIVGHNGSGKSTIAKLMIGIEKVKSGEI---------FYNNQAITDDN 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 81 AT--------VFEEMSKPFehikrMESLIKEETDW-LSKHANDYDsdtyKTHMSRYESLSnQFEQLEGYQYESkiktvlh 151
Cdd:PRK13648 78 FEklrkhigiVFQNPDNQF-----VGSIVKYDVAFgLENHAVPYD----EMHRRVSEALK-QVDMLERADYEP------- 140
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446524717 152 glnfseedfnkpiNDFSGGQKTRLSLAQMLLNEPDLLLLDEPTNHLDLETTKWLEDYLRYFKG----AIVIISHD 222
Cdd:PRK13648 141 -------------NALSGGQKQRVAIAGVLALNPSVIILDEATSMLDPDARQNLLDLVRKVKSehniTIISITHD 202
|
|
| tauB |
PRK11248 |
taurine ABC transporter ATP-binding subunit; |
348-502 |
1.17e-06 |
|
taurine ABC transporter ATP-binding subunit;
Pssm-ID: 183056 [Multi-domain] Cd Length: 255 Bit Score: 50.47 E-value: 1.17e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 348 ISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITFGANLQIGYYDQKQAEFKSS-----KTILDYVWDQYPLMN 422
Cdd:PRK11248 20 INLTLESGELLVVLGPSGCGKTTLLNLIAGFVPYQHGSITLDGKPVEGPGAERGVVFQNEgllpwRNVQDNVAFGLQLAG 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 423 -EKDIRAVLGRFLFVQDDV----KKIINDLSGGEKARLQLALLMLQRDNVLILDEPTNHLDIDSKE-MLEQALQHFEGT- 495
Cdd:PRK11248 100 vEKMQRLEIAHQMLKKVGLegaeKRYIWQLSGGQRQRVGIARALAANPQLLLLDEPFGALDAFTREqMQTLLLKLWQETg 179
|
....*....
gi 446524717 496 --ILFVSHD 502
Cdd:PRK11248 180 kqVLLITHD 188
|
|
| modC_ABC |
TIGR02142 |
molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding ... |
21-222 |
1.20e-06 |
|
molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding cassette (ABC) protein of the three subunit molybdate ABC transporter. The three proteins of this complex are homologous to proteins of the sulfate ABC transporter. Molybdenum may be used in nitrogenases of nitrogen-fixing bacteria and in molybdopterin cofactors. In some cases, molybdate may be transported by a sulfate transporter rather than by a specific molybdate transporter. [Transport and binding proteins, Anions]
Pssm-ID: 131197 [Multi-domain] Cd Length: 354 Bit Score: 50.88 E-value: 1.20e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 21 DVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNVS---------------KIKNLKLGYLTQQMTLnsnatvfe 85
Cdd:TIGR02142 15 DADFTLPGQGVTAIFGRSGSGKTTLIRLIAGLTRPDEGEIVlngrtlfdsrkgiflPPEKRRIGYVFQEARL-------- 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 86 emskpFEHIKRMESLIkeetdwlskhandydsdtYKTHMSRYESLSNQFEQLegyqyeskikTVLHGLnfsEEDFNKPIN 165
Cdd:TIGR02142 87 -----FPHLSVRGNLR------------------YGMKRARPSERRISFERV----------IELLGI---GHLLGRLPG 130
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446524717 166 DFSGGQKTRLSLAQMLLNEPDLLLLDEPTNHLDL----ETTKWLEDYLRYFKGAIVIISHD 222
Cdd:TIGR02142 131 RLSGGEKQRVAIGRALLSSPRLLLMDEPLAALDDprkyEILPYLERLHAEFGIPILYVSHS 191
|
|
| cbiO |
PRK13639 |
cobalt transporter ATP-binding subunit; Provisional |
330-514 |
1.23e-06 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184199 [Multi-domain] Cd Length: 275 Bit Score: 50.46 E-value: 1.23e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 330 VMHVKNLEIGYQ--TAITKPISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITF-GANLQigyYDQKqAEFKS 406
Cdd:PRK13639 1 ILETRDLKYSYPdgTEALKGINFKAEKGEMVALLGPNGAGKSTLFLHFNGILKPTSGEVLIkGEPIK---YDKK-SLLEV 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 407 SKTIlDYVW----DQ-----------YPLMN--------EKDIRAVLGRfLFVQDDVKKIINDLSGGEKARLQLALLMLQ 463
Cdd:PRK13639 77 RKTV-GIVFqnpdDQlfaptveedvaFGPLNlglskeevEKRVKEALKA-VGMEGFENKPPHHLSGGQKKRVAIAGILAM 154
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 446524717 464 RDNVLILDEPTNHLDIDSKEMLEQALQHF--EG-TILFVSHDRYFINQLANKVF 514
Cdd:PRK13639 155 KPEIIVLDEPTSGLDPMGASQIMKLLYDLnkEGiTIIISTHDVDLVPVYADKVY 208
|
|
| ABCG_EPDR |
cd03213 |
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette ... |
10-88 |
1.41e-06 |
|
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily; ABCG transporters are involved in eye pigment (EP) precursor transport, regulation of lipid-trafficking mechanisms, and pleiotropic drug resistance (DR). DR is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. Compared to other members of the ABC transporter subfamilies, the ABCG transporter family is composed of proteins that have an ATP-binding cassette domain at the N-terminus and a TM (transmembrane) domain at the C-terminus.
Pssm-ID: 213180 [Multi-domain] Cd Length: 194 Bit Score: 49.09 E-value: 1.41e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 10 SKSFDGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAG--VENYDSGNV------SKIKNLK--LGYLTQQMTLNS 79
Cdd:cd03213 16 SPSKSGKQLLKNVSGKAKPGELTAIMGPSGAGKSTLLNALAGrrTGLGVSGEVlingrpLDKRSFRkiIGYVPQDDILHP 95
|
....*....
gi 446524717 80 NATVFEEMS 88
Cdd:cd03213 96 TLTVRETLM 104
|
|
| modC |
PRK11144 |
molybdenum ABC transporter ATP-binding protein ModC; |
359-555 |
1.56e-06 |
|
molybdenum ABC transporter ATP-binding protein ModC;
Pssm-ID: 182993 [Multi-domain] Cd Length: 352 Bit Score: 50.64 E-value: 1.56e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 359 AIIGPNGIGKSTLIKTIA---NQQK---ALNGYITF----GANL-----QIGYYDQKQAEF--------------KSSKT 409
Cdd:PRK11144 28 AIFGRSGAGKTSLINAISgltRPQKgriVLNGRVLFdaekGICLppekrRIGYVFQDARLFphykvrgnlrygmaKSMVA 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 410 ILDYVWDqypLMnekDIRAVLGRFLFvqddvkkiinDLSGGEKARLQLALLMLQRDNVLILDEPTNHLDIDSK-EM---L 485
Cdd:PRK11144 108 QFDKIVA---LL---GIEPLLDRYPG----------SLSGGEKQRVAIGRALLTAPELLLMDEPLASLDLPRKrELlpyL 171
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446524717 486 EQALQHFEGTILFVSHDRYFINQLANKVfdLTIDGGKMYLGDyqyYIEKVEEAEALKAHQ--EEQS----VNVQAH 555
Cdd:PRK11144 172 ERLAREINIPILYVSHSLDEILRLADRV--VVLEQGKVKAFG---PLEEVWASSAMRPWLpkEEQSsilkVTVLEH 242
|
|
| tauB |
PRK11248 |
taurine ABC transporter ATP-binding subunit; |
3-60 |
1.75e-06 |
|
taurine ABC transporter ATP-binding subunit;
Pssm-ID: 183056 [Multi-domain] Cd Length: 255 Bit Score: 49.70 E-value: 1.75e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 446524717 3 LLQLNHISKSFDGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNV 60
Cdd:PRK11248 1 MLQISHLYADYGGKPALEDINLTLESGELLVVLGPSGCGKTTLLNLIAGFVPYQHGSI 58
|
|
| cbiO |
PRK13641 |
energy-coupling factor transporter ATPase; |
348-523 |
1.83e-06 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237456 [Multi-domain] Cd Length: 287 Bit Score: 50.21 E-value: 1.83e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 348 ISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITFGanlqiGYYDQKQAEFKSSKTILDYVW--DQYP---LMN 422
Cdd:PRK13641 26 ISFELEEGSFVALVGHTGSGKSTLMQHFNALLKPSSGTITIA-----GYHITPETGNKNLKKLRKKVSlvFQFPeaqLFE 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 423 E---KDIRAVLGRFLFVQDDVKK--------------IIN----DLSGGEKARLQLALLMLQRDNVLILDEPTNHLDIDS 481
Cdd:PRK13641 101 NtvlKDVEFGPKNFGFSEDEAKEkalkwlkkvglsedLISkspfELSGGQMRRVAIAGVMAYEPEILCLDEPAAGLDPEG 180
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 446524717 482 -KEMLE-----QALQHfegTILFVSHDRYFINQLANKVfdLTIDGGKM 523
Cdd:PRK13641 181 rKEMMQlfkdyQKAGH---TVILVTHNMDDVAEYADDV--LVLEHGKL 223
|
|
| PRK13538 |
PRK13538 |
cytochrome c biogenesis heme-transporting ATPase CcmA; |
3-61 |
1.84e-06 |
|
cytochrome c biogenesis heme-transporting ATPase CcmA;
Pssm-ID: 184125 [Multi-domain] Cd Length: 204 Bit Score: 49.03 E-value: 1.84e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 446524717 3 LLQLNHISKSFDGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNVS 61
Cdd:PRK13538 1 MLEARNLACERDERILFSGLSFTLNAGELVQIEGPNGAGKTSLLRILAGLARPDAGEVL 59
|
|
| PRK14246 |
PRK14246 |
phosphate ABC transporter ATP-binding protein; Provisional |
14-222 |
1.90e-06 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172734 [Multi-domain] Cd Length: 257 Bit Score: 49.66 E-value: 1.90e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 14 DGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAG-VENYDSGNVSKIKNLKLGyltqqmtlnsnatvfeemskpfE 92
Cdd:PRK14246 21 NDKAILKDITIKIPNNSIFGIMGPSGSGKSTLLKVLNRlIEIYDSKIKVDGKVLYFG----------------------K 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 93 HIKRMESL-IKEETDWLSKHANDYdsdtykTHMSRYESLSNQFEQlEGYQYESKIKTVLH------GLNFSEED-FNKPI 164
Cdd:PRK14246 79 DIFQIDAIkLRKEVGMVFQQPNPF------PHLSIYDNIAYPLKS-HGIKEKREIKKIVEeclrkvGLWKEVYDrLNSPA 151
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 165 NDFSGGQKTRLSLAQMLLNEPDLLLLDEPTNHLDLETTKWLEDYLRYFKG--AIVIISHD 222
Cdd:PRK14246 152 SQLSGGQQQRLTIARALALKPKVLLMDEPTSMIDIVNSQAIEKLITELKNeiAIVIVSHN 211
|
|
| Rli1 |
COG1245 |
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ... |
354-479 |
2.20e-06 |
|
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];
Pssm-ID: 440858 [Multi-domain] Cd Length: 592 Bit Score: 50.55 E-value: 2.20e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 354 KGDHIAIIGPNGIGKSTLIKTIANQQKA-LNGY---------ITFGANLQIGYYDQKQAEfKSSKTIL--DYVwDQYP-- 419
Cdd:COG1245 98 KGKVTGILGPNGIGKSTALKILSGELKPnLGDYdeepswdevLKRFRGTELQDYFKKLAN-GEIKVAHkpQYV-DLIPkv 175
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 420 -------LMNEKDIRAVLG---RFLFVQDDVKKIINDLSGGEKARLQLALLMLQRDNVLILDEPTNHLDI 479
Cdd:COG1245 176 fkgtvreLLEKVDERGKLDelaEKLGLENILDRDISELSGGELQRVAIAAALLRDADFYFFDEPSSYLDI 245
|
|
| PRK13633 |
PRK13633 |
energy-coupling factor transporter ATPase; |
21-221 |
2.25e-06 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237453 [Multi-domain] Cd Length: 280 Bit Score: 49.70 E-value: 2.25e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 21 DVDFEVKTGERIGIVGRNGAGKSTLMK-------------IIAGVENYDSGNVSKIKNlKLGYLTQQMTLNSNATVFEEm 87
Cdd:PRK13633 28 DVNLEVKKGEFLVILGRNGSGKSTIAKhmnallipsegkvYVDGLDTSDEENLWDIRN-KAGMVFQNPDNQIVATIVEE- 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 88 SKPF--EHIKRMESLIKEETDWLSKHANDYDSDTYKTHMsryeslsnqfeqlegyqyeskiktvlhglnfseedfnkpin 165
Cdd:PRK13633 106 DVAFgpENLGIPPEEIRERVDESLKKVGMYEYRRHAPHL----------------------------------------- 144
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 166 dFSGGQKTRLSLAQMLLNEPDLLLLDEPTNHLD----LETTKWLEDYLRYFKGAIVIISH 221
Cdd:PRK13633 145 -LSGGQKQRVAIAGILAMRPECIIFDEPTAMLDpsgrREVVNTIKELNKKYGITIILITH 203
|
|
| ABC_OpuCA_Osmoprotection |
cd03295 |
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding ... |
4-222 |
2.29e-06 |
|
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing in a hyperosmolar environment. ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition, to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213262 [Multi-domain] Cd Length: 242 Bit Score: 49.22 E-value: 2.29e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 4 LQLNHISKSF-DGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSG-------NVSKIKNLKL----GYL 71
Cdd:cd03295 1 IEFENVTKRYgGGKKAVNNLNLEIAKGEFLVLIGPSGSGKTTTMKMINRLIEPTSGeifidgeDIREQDPVELrrkiGYV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 72 TQQMTLNSNATVfeemskpFEHIKRMESLIKeetdWLSKhandydsdtykthmsryeslsnqfeqlegyQYESKIKTVLH 151
Cdd:cd03295 81 IQQIGLFPHMTV-------EENIALVPKLLK----WPKE------------------------------KIRERADELLA 119
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446524717 152 GLNFSEEDF-NKPINDFSGGQKTRLSLAQMLLNEPDLLLLDEPTNHLDLETTKWLEDYLRYFKGA----IVIISHD 222
Cdd:cd03295 120 LVGLDPAEFaDRYPHELSGGQQQRVGVARALAADPPLLLMDEPFGALDPITRDQLQEEFKRLQQElgktIVFVTHD 195
|
|
| thiQ |
PRK10771 |
thiamine ABC transporter ATP-binding protein ThiQ; |
23-59 |
2.63e-06 |
|
thiamine ABC transporter ATP-binding protein ThiQ;
Pssm-ID: 182716 [Multi-domain] Cd Length: 232 Bit Score: 48.81 E-value: 2.63e-06
10 20 30
....*....|....*....|....*....|....*..
gi 446524717 23 DFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGN 59
Cdd:PRK10771 19 DLTVERGERVAILGPSGAGKSTLLNLIAGFLTPASGS 55
|
|
| bacteriocin_ABC |
TIGR01193 |
ABC-type bacteriocin transporter; This model describes ABC-type bacteriocin transporter. The ... |
4-260 |
3.14e-06 |
|
ABC-type bacteriocin transporter; This model describes ABC-type bacteriocin transporter. The amino terminal domain (pfam03412) processes the N-terminal leader peptide from the bacteriocin while C-terminal domains resemble ABC transporter membrane protein and ATP-binding cassette domain. In general, bacteriocins are agents which are responsible for killing or inhibiting the closely related species or even different strains of the same species. Bacteriocins are usually encoded by bacterial plasmids. Bacteriocins are named after the species and hence in literature one encounters various names e.g., leucocin from Leuconostic geldium; pedicocin from Pedicoccus acidilactici; sakacin from Lactobacillus sake etc. [Protein fate, Protein and peptide secretion and trafficking, Protein fate, Protein modification and repair, Transport and binding proteins, Other]
Pssm-ID: 130261 [Multi-domain] Cd Length: 708 Bit Score: 50.51 E-value: 3.14e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 4 LQLNHISKSFD-GEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNVS----KIKNLKLGYLTQQMT-L 77
Cdd:TIGR01193 474 IVINDVSYSYGyGSNILSDISLTIKMNSKTTIVGMSGSGKSTLAKLLVGFFQARSGEILlngfSLKDIDRHTLRQFINyL 553
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 78 NSNATVFEEmskpfehiKRMESLIkeetdwLSKHANDYDSDTYKThmSRYESLSNQFEQL-EGYQYEskiktvlhglnFS 156
Cdd:TIGR01193 554 PQEPYIFSG--------SILENLL------LGAKENVSQDEIWAA--CEIAEIKDDIENMpLGYQTE-----------LS 606
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 157 EEDFNkpindFSGGQKTRLSLAQMLLNEPDLLLLDEPTNHLDLETT-KWLEDYLRYFKGAIVIISHdRYFLDKIVTQIYD 235
Cdd:TIGR01193 607 EEGSS-----ISGGQKQRIALARALLTDSKVLILDESTSNLDTITEkKIVNNLLNLQDKTIIFVAH-RLSVAKQSDKIIV 680
|
250 260
....*....|....*....|....*
gi 446524717 236 VALGDVKRyVGNYEEFIQQRDLYYQ 260
Cdd:TIGR01193 681 LDHGKIIE-QGSHDELLDRNGFYAS 704
|
|
| MsbA_lipidA |
TIGR02203 |
lipid A export permease/ATP-binding protein MsbA; This family consists of a single polypeptide ... |
3-221 |
3.70e-06 |
|
lipid A export permease/ATP-binding protein MsbA; This family consists of a single polypeptide chain transporter in the ATP-binding cassette (ABC) transporter family, MsbA, which exports lipid A. It may also act in multidrug resistance. Lipid A, a part of lipopolysaccharide, is found in the outer leaflet of the outer membrane of most Gram-negative bacteria. Members of this family are restricted to the Proteobacteria (although lipid A is more broadly distributed) and often are clustered with lipid A biosynthesis genes. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides, Transport and binding proteins, Other]
Pssm-ID: 131258 [Multi-domain] Cd Length: 571 Bit Score: 50.10 E-value: 3.70e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 3 LLQLNHISKSF--DGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNV----SKIKNLKLGYLTQQMT 76
Cdd:TIGR02203 330 DVEFRNVTFRYpgRDRPALDSISLVIEPGETVALVGRSGSGKSTLVNLIPRFYEPDSGQIlldgHDLADYTLASLRRQVA 409
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 77 LNS------NATVFEEMSkpfehIKRMESLIKEETDWLSKHANDYDsdtykthmsryesLSNQFEqlEGYQYESKIKTVL 150
Cdd:TIGR02203 410 LVSqdvvlfNDTIANNIA-----YGRTEQADRAEIERALAAAYAQD-------------FVDKLP--LGLDTPIGENGVL 469
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446524717 151 hglnfseedfnkpindFSGGQKTRLSLAQMLLNEPDLLLLDEPTNHLDLETTKWLEDYL-RYFKG-AIVIISH 221
Cdd:TIGR02203 470 ----------------LSGGQRQRLAIARALLKDAPILILDEATSALDNESERLVQAALeRLMQGrTTLVIAH 526
|
|
| PRK11160 |
PRK11160 |
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed |
3-260 |
3.75e-06 |
|
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
Pssm-ID: 236865 [Multi-domain] Cd Length: 574 Bit Score: 49.82 E-value: 3.75e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 3 LLQLNHISKSFDGED--IFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIagVENYD--SGNVS----KIKNLKLGYLTQQ 74
Cdd:PRK11160 338 SLTLNNVSFTYPDQPqpVLKGLSLQIKAGEKVALLGRTGCGKSTLLQLL--TRAWDpqQGEILlngqPIADYSEAALRQA 415
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 75 MTLNS------NATVFEE--MSKPfehikrmeslikeetdwlskHANDydsdtykthmsryESLSNQFEQLEgyqyeski 146
Cdd:PRK11160 416 ISVVSqrvhlfSATLRDNllLAAP--------------------NASD-------------EALIEVLQQVG-------- 454
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 147 ktvLHGLNFSEEDFNKPIND----FSGGQKTRLSLAQMLLNEPDLLLLDEPTNHLDLET-TKWLEDYLRYFKGAIVI-IS 220
Cdd:PRK11160 455 ---LEKLLEDDKGLNAWLGEggrqLSGGEQRRLGIARALLHDAPLLLLDEPTEGLDAETeRQILELLAEHAQNKTVLmIT 531
|
250 260 270 280
....*....|....*....|....*....|....*....|
gi 446524717 221 HDRYFLDKIvTQIYDVALGDVkRYVGNYEEFIQQRDLYYQ 260
Cdd:PRK11160 532 HRLTGLEQF-DRICVMDNGQI-IEQGTHQELLAQQGRYYQ 569
|
|
| ABC_PstB_phosphate_transporter |
cd03260 |
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of ... |
4-222 |
3.92e-06 |
|
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of fundamental importance in the cell physiology of bacteria because phosphate is required as a nutrient. The Pst system of E. coli comprises four distinct subunits encoded by the pstS, pstA, pstB, and pstC genes. The PstS protein is a phosphate-binding protein located in the periplasmic space. PstA and PstC are hydrophobic and they form the transmembrane portion of the Pst system. PstB is the catalytic subunit, which couples the energy of ATP hydrolysis to the import of phosphate across cellular membranes through the Pst system, often referred as ABC-protein. PstB belongs to one of the largest superfamilies of proteins characterized by a highly conserved adenosine triphosphate (ATP) binding cassette (ABC), which is also a nucleotide binding domain (NBD).
Pssm-ID: 213227 [Multi-domain] Cd Length: 227 Bit Score: 48.33 E-value: 3.92e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 4 LQLNHISKSFDGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENY-----DSGNV----SKIKNL-------- 66
Cdd:cd03260 1 IELRDLNVYYGDKHALKDISLDIPKGEITALIGPSGCGKSTLLRLLNRLNDLipgapDEGEVlldgKDIYDLdvdvlelr 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 67 -KLGYLTQQMTLnSNATVFEEMSKPfehIKRMESLIKEETDWLSKHAndydsdtykthmsryeslsnqfeqLEGYQYESK 145
Cdd:cd03260 81 rRVGMVFQKPNP-FPGSIYDNVAYG---LRLHGIKLKEELDERVEEA------------------------LRKAALWDE 132
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446524717 146 IKTVLHGLnfseedfnkpinDFSGGQKTRLSLAQMLLNEPDLLLLDEPTNHLDLETTKWLEDYLRYFKG--AIVIISHD 222
Cdd:cd03260 133 VKDRLHAL------------GLSGGQQQRLCLARALANEPEVLLLDEPTSALDPISTAKIEELIAELKKeyTIVIVTHN 199
|
|
| ABCG_White |
cd03234 |
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ... |
16-220 |
4.04e-06 |
|
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ABC transporters homologous to the Drosophila white gene, which acts as a dimeric importer for eye pigment precursors. The eye pigmentation of Drosophila is developed from the synthesis and deposition in the cells of red pigments, which are synthesized from guanine, and brown pigments, which are synthesized from tryptophan. The pigment precursors are encoded by the white, brown, and scarlet genes, respectively. Evidence from genetic and biochemical studies suggest that the White and Brown proteins function as heterodimers to import guanine, while the White and Scarlet proteins function to import tryptophan. However, a recent study also suggests that White may be involved in the transport of a metabolite, such as 3-hydroxykynurenine, across intracellular membranes. Mammalian ABC transporters belonging to the White subfamily (ABCG1, ABCG5, and ABCG8) have been shown to be involved in the regulation of lipid-trafficking mechanisms in macrophages, hepatocytes, and intestinal mucosa cells. ABCG1 (ABC8), the human homolog of the Drosophila white gene is induced in monocyte-derived macrophages during cholesterol influx mediated by acetylated low-density lipoprotein. It is possible that human ABCG1 forms heterodimers with several heterologous partners.
Pssm-ID: 213201 [Multi-domain] Cd Length: 226 Bit Score: 48.42 E-value: 4.04e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 16 EDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAG-VENYD--SGNV------SKIKNLK--LGYLTQQMTLNSNATVF 84
Cdd:cd03234 20 ARILNDVSLHVESGQVMAILGSSGSGKTTLLDAISGrVEGGGttSGQIlfngqpRKPDQFQkcVAYVRQDDILLPGLTVR 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 85 EemSKPFEHIKRMESLI------KEETDWLSKHANDydsdtykthmsryeslsnqfEQLEGYQYESkiktvlhglnfsee 158
Cdd:cd03234 100 E--TLTYTAILRLPRKSsdairkKRVEDVLLRDLAL--------------------TRIGGNLVKG-------------- 143
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446524717 159 dfnkpindFSGGQKTRLSLAQMLLNEPDLLLLDEPTNHLD----LETTKWLEDYLRyfKGAIVIIS 220
Cdd:cd03234 144 --------ISGGERRRVSIAVQLLWDPKVLILDEPTSGLDsftaLNLVSTLSQLAR--RNRIVILT 199
|
|
| PRK15134 |
PRK15134 |
microcin C ABC transporter ATP-binding protein YejF; Provisional |
447-513 |
4.07e-06 |
|
microcin C ABC transporter ATP-binding protein YejF; Provisional
Pssm-ID: 237917 [Multi-domain] Cd Length: 529 Bit Score: 49.70 E-value: 4.07e-06
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446524717 447 LSGGEKARLQLALLMLQRDNVLILDEPTNHLDIDSKEMLEQAL----QHFEGTILFVSHDRYFINQLANKV 513
Cdd:PRK15134 157 LSGGERQRVMIAMALLTRPELLIADEPTTALDVSVQAQILQLLrelqQELNMGLLFITHNLSIVRKLADRV 227
|
|
| ABCC_MRP_domain1 |
cd03250 |
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This ... |
10-178 |
4.09e-06 |
|
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This subfamily is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213217 [Multi-domain] Cd Length: 204 Bit Score: 47.85 E-value: 4.09e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 10 SKSFDGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNVSKIKnlKLGYLTQQ---MtlnsNATVFEE 86
Cdd:cd03250 12 SGEQETSFTLKDINLEVPKGELVAIVGPVGSGKSSLLSALLGELEKLSGSVSVPG--SIAYVSQEpwiQ----NGTIREN 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 87 --MSKPFEHikrmeslikeetdwlskhandydsdtykthmSRYE------SLSNQFEQLEGyqyesKIKTVLH--GLNfs 156
Cdd:cd03250 86 ilFGKPFDE-------------------------------ERYEkvikacALEPDLEILPD-----GDLTEIGekGIN-- 127
|
170 180
....*....|....*....|..
gi 446524717 157 eedfnkpindFSGGQKTRLSLA 178
Cdd:cd03250 128 ----------LSGGQKQRISLA 139
|
|
| ModC |
COG4148 |
ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and ... |
1-61 |
4.22e-06 |
|
ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and metabolism]; ABC-type molybdate transport system, ATPase component ModC is part of the Pathway/BioSystem: Molybdopterin biosynthesis
Pssm-ID: 443319 [Multi-domain] Cd Length: 358 Bit Score: 49.33 E-value: 4.22e-06
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446524717 1 MILLQLNHISKSFDgedifTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNVS 61
Cdd:COG4148 2 MLEVDFRLRRGGFT-----LDVDFTLPGRGVTALFGPSGSGKTTLLRAIAGLERPDSGRIR 57
|
|
| MglA |
COG1129 |
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; |
2-72 |
4.26e-06 |
|
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440745 [Multi-domain] Cd Length: 497 Bit Score: 49.63 E-value: 4.26e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 2 ILLQLNHISksfdGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNVS------KIKN------LKLG 69
Cdd:COG1129 255 VVLEVEGLS----VGGVVRDVSFSVRAGEILGIAGLVGAGRTELARALFGADPADSGEIRldgkpvRIRSprdairAGIA 330
|
...
gi 446524717 70 YLT 72
Cdd:COG1129 331 YVP 333
|
|
| PRK11264 |
PRK11264 |
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional |
1-225 |
4.30e-06 |
|
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional
Pssm-ID: 183063 [Multi-domain] Cd Length: 250 Bit Score: 48.59 E-value: 4.30e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 1 MILLQLNHISKSFDGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNVskiknlKLGyltqQMTLNSn 80
Cdd:PRK11264 1 MSAIEVKNLVKKFHGQTVLHGIDLEVKPGEVVAIIGPSGSGKTTLLRCINLLEQPEAGTI------RVG----DITIDT- 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 81 atvfeemSKPFEHIKRMESLIKEETDWLSKHANDYDSDTykthmsryeSLSNQFE---QLEGYQYESKIKTVLH-----G 152
Cdd:PRK11264 70 -------ARSLSQQKGLIRQLRQHVGFVFQNFNLFPHRT---------VLENIIEgpvIVKGEPKEEATARAREllakvG 133
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446524717 153 LNFSEEDFNKPIndfSGGQKTRLSLAQMLLNEPDLLLLDEPTNHLDLETTKWLEDYLRYF---KGAIVIISHDRYF 225
Cdd:PRK11264 134 LAGKETSYPRRL---SGGQQQRVAIARALAMRPEVILFDEPTSALDPELVGEVLNTIRQLaqeKRTMVIVTHEMSF 206
|
|
| ABC_Carb_Monos_II |
cd03215 |
Second domain of the ATP-binding cassette component of monosaccharide transport system; This ... |
327-523 |
4.51e-06 |
|
Second domain of the ATP-binding cassette component of monosaccharide transport system; This family represents domain II of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. In members of Carb_Monos family the single hydrophobic gene product forms a homodimer, while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.
Pssm-ID: 213182 [Multi-domain] Cd Length: 182 Bit Score: 47.43 E-value: 4.51e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 327 GNDVMHVKNLEIGYQTaitKPISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITFganlqigyyDQKQAEFKS 406
Cdd:cd03215 1 GEPVLEVRGLSVKGAV---RDVSFEVRAGEIVGIAGLVGNGQTELAEALFGLRPPASGEITL---------DGKPVTRRS 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 407 SKTILD----YVwdqyP-------LMNEKDIR--AVLGRFLfvqddvkkiindlSGGEKARLQLALLMLQRDNVLILDEP 473
Cdd:cd03215 69 PRDAIRagiaYV----PedrkregLVLDLSVAenIALSSLL-------------SGGNQQKVVLARWLARDPRVLILDEP 131
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 446524717 474 TNHLDIDSKE-----MLEQALQhfeGT-ILFVSHDRYFINQLANKVfdLTIDGGKM 523
Cdd:cd03215 132 TRGVDVGAKAeiyrlIRELADA---GKaVLLISSELDELLGLCDRI--LVMYEGRI 182
|
|
| GlnQ |
COG1126 |
ABC-type polar amino acid transport system, ATPase component [Amino acid transport and ... |
3-203 |
4.61e-06 |
|
ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 440743 [Multi-domain] Cd Length: 239 Bit Score: 48.45 E-value: 4.61e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 3 LLQLNHISKSFDGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNVS--------KIKNL-----KLG 69
Cdd:COG1126 1 MIEIENLHKSFGDLEVLKGISLDVEKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTITvdgedltdSKKDInklrrKVG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 70 YLTQQMTLNSNATVFEEMSKPFEHIKRMEsliKEET-----DWLSK-----HANDYDSdtykthmsryeslsnqfeQLeg 139
Cdd:COG1126 81 MVFQQFNLFPHLTVLENVTLAPIKVKKMS---KAEAeeramELLERvgladKADAYPA------------------QL-- 137
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446524717 140 yqyeskiktvlhglnfseedfnkpindfSGGQKTRL----SLAQ----MLlnepdlllLDEPTNHLDLETTK 203
Cdd:COG1126 138 ----------------------------SGGQQQRVaiarALAMepkvML--------FDEPTSALDPELVG 173
|
|
| cbiO |
PRK13644 |
energy-coupling factor transporter ATPase; |
3-67 |
4.62e-06 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 106587 [Multi-domain] Cd Length: 274 Bit Score: 48.83 E-value: 4.62e-06
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446524717 3 LLQLNHISKSF-DGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAG----------VENYDSGNVSKIKNLK 67
Cdd:PRK13644 1 MIRLENVSYSYpDGTPALENINLVIKKGEYIGIIGKNGSGKSTLALHLNGllrpqkgkvlVSGIDTGDFSKLQGIR 76
|
|
| ABCC_ATM1_transporter |
cd03253 |
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC ... |
4-74 |
5.06e-06 |
|
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC transporter that is expressed in the mitochondria. Although the specific function of ATM1 is unknown, its disruption results in the accumulation of excess mitochondrial iron, loss of mitochondrial cytochromes, oxidative damage to mitochondrial DNA, and decreased levels of cytosolic heme proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213220 [Multi-domain] Cd Length: 236 Bit Score: 48.00 E-value: 5.06e-06
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446524717 4 LQLNHISKSFDGE-DIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNV----SKIKNLKLGYLTQQ 74
Cdd:cd03253 1 IEFENVTFAYDPGrPVLKDVSFTIPAGKKVAIVGPSGSGKSTILRLLFRFYDVSSGSIlidgQDIREVTLDSLRRA 76
|
|
| thiQ |
PRK10771 |
thiamine ABC transporter ATP-binding protein ThiQ; |
349-501 |
6.00e-06 |
|
thiamine ABC transporter ATP-binding protein ThiQ;
Pssm-ID: 182716 [Multi-domain] Cd Length: 232 Bit Score: 48.04 E-value: 6.00e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 349 SIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKA------LNG------------------------YITFGANLQIGYY- 397
Cdd:PRK10771 19 DLTVERGERVAILGPSGAGKSTLLNLIAGFLTPasgsltLNGqdhtttppsrrpvsmlfqennlfsHLTVAQNIGLGLNp 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 398 ------DQKQAefkssktildyvwdqyplmnekdIRAVLGRfLFVQDDVKKIINDLSGGEKARLQLALLMLQRDNVLILD 471
Cdd:PRK10771 99 glklnaAQREK-----------------------LHAIARQ-MGIEDLLARLPGQLSGGQRQRVALARCLVREQPILLLD 154
|
170 180 190
....*....|....*....|....*....|....
gi 446524717 472 EPTNHLDIDSK-EML---EQALQHFEGTILFVSH 501
Cdd:PRK10771 155 EPFSALDPALRqEMLtlvSQVCQERQLTLLMVSH 188
|
|
| ABCG_PDR_domain1 |
cd03233 |
First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette ... |
344-516 |
6.18e-06 |
|
First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213200 [Multi-domain] Cd Length: 202 Bit Score: 47.26 E-value: 6.18e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 344 ITKPISIEVSKGDHIAIIGPNGIGKSTLIKTIANQ---QKALNGYITFGAnlqigyYDQKQAEFKSSKTILdYVwdqypl 420
Cdd:cd03233 22 ILKDFSGVVKPGEMVLVLGRPGSGCSTLLKALANRtegNVSVEGDIHYNG------IPYKEFAEKYPGEII-YV------ 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 421 mNEKDIRAVLgrfLFVQDDVK--------KIINDLSGGEKARLQLALLMLQRDNVLILDEPTNHLDIDSK-EMLE--QAL 489
Cdd:cd03233 89 -SEEDVHFPT---LTVRETLDfalrckgnEFVRGISGGERKRVSIAEALVSRASVLCWDNSTRGLDSSTAlEILKciRTM 164
|
170 180
....*....|....*....|....*..
gi 446524717 490 QHFEGTILFVShdryfINQLANKVFDL 516
Cdd:cd03233 165 ADVLKTTTFVS-----LYQASDEIYDL 186
|
|
| PRK10535 |
PRK10535 |
macrolide ABC transporter ATP-binding protein/permease MacB; |
341-502 |
6.70e-06 |
|
macrolide ABC transporter ATP-binding protein/permease MacB;
Pssm-ID: 182528 [Multi-domain] Cd Length: 648 Bit Score: 49.34 E-value: 6.70e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 341 QTAITKPISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNG-YITFGANLQIGYYDQKQAEFKSSktiLDYVWDQYP 419
Cdd:PRK10535 20 QVEVLKGISLDIYAGEMVAIVGASGSGKSTLMNILGCLDKPTSGtYRVAGQDVATLDADALAQLRREH---FGFIFQRYH 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 420 LM--------------------NEKDIRAV--LGRfLFVQDDVKKIINDLSGGEKARLQLALLMLQRDNVLILDEPTNHL 477
Cdd:PRK10535 97 LLshltaaqnvevpavyaglerKQRLLRAQelLQR-LGLEDRVEYQPSQLSGGQQQRVSIARALMNGGQVILADEPTGAL 175
|
170 180
....*....|....*....|....*....
gi 446524717 478 DIDSKE----MLEQaLQHFEGTILFVSHD 502
Cdd:PRK10535 176 DSHSGEevmaILHQ-LRDRGHTVIIVTHD 203
|
|
| MK0520 |
COG2401 |
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction ... |
1-51 |
7.42e-06 |
|
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction only];
Pssm-ID: 441957 [Multi-domain] Cd Length: 222 Bit Score: 47.65 E-value: 7.42e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 446524717 1 MILLQLNHISKSFDGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAG 51
Cdd:COG2401 28 AIVLEAFGVELRVVERYVLRDLNLEIEPGEIVLIVGASGSGKSTLLRLLAG 78
|
|
| type_I_sec_PrtD |
TIGR01842 |
type I secretion system ABC transporter, PrtD family; Type I protein secretion is a system in ... |
17-254 |
8.32e-06 |
|
type I secretion system ABC transporter, PrtD family; Type I protein secretion is a system in some Gram-negative bacteria to export proteins (often proteases) across both inner and outer membranes to the extracellular medium. This is one of three proteins of the type I secretion apparatus. Targeted proteins are not cleaved at the N-terminus, but rather carry signals located toward the extreme C-terminus to direct type I secretion. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 200134 [Multi-domain] Cd Length: 544 Bit Score: 48.88 E-value: 8.32e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 17 DIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNV----SKIKNL-------KLGYLTQQMTLNSnATVFE 85
Cdd:TIGR01842 332 PTLRGISFSLQAGEALAIIGPSGSGKSTLARLIVGIWPPTSGSVrldgADLKQWdretfgkHIGYLPQDVELFP-GTVAE 410
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 86 emskpfeHIKRM-ESLIKEETDWLSKHANDYDsdtykthmsryesLSNQFEQlegyQYESKIKTVLHGLnfseedfnkpi 164
Cdd:TIGR01842 411 -------NIARFgENADPEKIIEAAKLAGVHE-------------LILRLPD----GYDTVIGPGGATL----------- 455
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 165 ndfSGGQKTRLSLAQMLLNEPDLLLLDEPTNHLDLETTKWLEDYLRYFK---GAIVIISHdRYFLDKIVTQIYDVALGDV 241
Cdd:TIGR01842 456 ---SGGQRQRIALARALYGDPKLVVLDEPNSNLDEEGEQALANAIKALKargITVVVITH-RPSLLGCVDKILVLQDGRI 531
|
250
....*....|...
gi 446524717 242 KRYvGNYEEFIQQ 254
Cdd:TIGR01842 532 ARF-GERDEVLAK 543
|
|
| ABC_OpuCA_Osmoprotection |
cd03295 |
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding ... |
348-502 |
1.07e-05 |
|
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing in a hyperosmolar environment. ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition, to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213262 [Multi-domain] Cd Length: 242 Bit Score: 47.30 E-value: 1.07e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 348 ISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITF-GANL----------QIGYYDQKQAEFkSSKTILDYV-- 414
Cdd:cd03295 20 LNLEIAKGEFLVLIGPSGSGKTTTMKMINRLIEPTSGEIFIdGEDIreqdpvelrrKIGYVIQQIGLF-PHMTVEENIal 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 415 ------WDQyplmnEKDIRAVLGRFLFVQDDVKKIIN----DLSGGEKARLQLALLMLQRDNVLILDEPTNHLDIDSKEM 484
Cdd:cd03295 99 vpkllkWPK-----EKIRERADELLALVGLDPAEFADryphELSGGQQQRVGVARALAADPPLLLMDEPFGALDPITRDQ 173
|
170 180
....*....|....*....|..
gi 446524717 485 LEQALQHFE----GTILFVSHD 502
Cdd:cd03295 174 LQEEFKRLQqelgKTIVFVTHD 195
|
|
| PRK15056 |
PRK15056 |
manganese/iron ABC transporter ATP-binding protein; |
349-500 |
1.15e-05 |
|
manganese/iron ABC transporter ATP-binding protein;
Pssm-ID: 185016 [Multi-domain] Cd Length: 272 Bit Score: 47.57 E-value: 1.15e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 349 SIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYIT---------FGANLqIGYYDQKQaEFKSSKTIL--DYV--- 414
Cdd:PRK15056 27 SFTVPGGSIAALVGVNGSGKSTLFKALMGFVRLASGKISilgqptrqaLQKNL-VAYVPQSE-EVDWSFPVLveDVVmmg 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 415 ------WDQYPLMNEKDI-RAVLGRfLFVQDDVKKIINDLSGGEKARLQLALLMLQRDNVLILDEPTNHLDIDSKEMLEQ 487
Cdd:PRK15056 105 ryghmgWLRRAKKRDRQIvTAALAR-VDMVEFRHRQIGELSGGQKKRVFLARAIAQQGQVILLDEPFTGVDVKTEARIIS 183
|
170
....*....|....*
gi 446524717 488 ALQHF--EGTILFVS 500
Cdd:PRK15056 184 LLRELrdEGKTMLVS 198
|
|
| cbiO |
PRK13632 |
cobalt transporter ATP-binding subunit; Provisional |
2-61 |
1.17e-05 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237452 [Multi-domain] Cd Length: 271 Bit Score: 47.29 E-value: 1.17e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446524717 2 ILLQLNHISKSFDGED--IFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNVS 61
Cdd:PRK13632 6 VMIKVENVSFSYPNSEnnALKNVSFEINEGEYVAILGHNGSGKSTISKILTGLLKPQSGEIK 67
|
|
| ABCC_MRP_domain2 |
cd03244 |
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C ... |
331-501 |
1.22e-05 |
|
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resistance lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213211 [Multi-domain] Cd Length: 221 Bit Score: 46.72 E-value: 1.22e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 331 MHVKNLEIGY---QTAITKPISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITF-GANL-QIGYYD------- 398
Cdd:cd03244 3 IEFKNVSLRYrpnLPPVLKNISFSIKPGEKVGIVGRTGSGKSSLLLALFRLVELSSGSILIdGVDIsKIGLHDlrsrisi 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 399 --QKQAEFksSKTI---LDyVWDQYPlmnEKDIRAVLGR---FLFVQDDVKKII-------NDLSGGEKARLQLALLMLQ 463
Cdd:cd03244 83 ipQDPVLF--SGTIrsnLD-PFGEYS---DEELWQALERvglKEFVESLPGGLDtvveeggENLSVGQRQLLCLARALLR 156
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 446524717 464 RDNVLILDEPTNHLDIDSKEMLEQALQ-HFEG-TILFVSH 501
Cdd:cd03244 157 KSKILVLDEATASVDPETDALIQKTIReAFKDcTVLTIAH 196
|
|
| PhnK |
COG1101 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
310-478 |
1.27e-05 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 440718 [Multi-domain] Cd Length: 264 Bit Score: 47.39 E-value: 1.27e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 310 MLDAKsaNIQFGFDRNTGNDVMHVKNleigyqtaitkpISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITF- 388
Cdd:COG1101 1 MLELK--NLSKTFNPGTVNEKRALDG------------LNLTIEEGDFVTVIGSNGAGKSTLLNAIAGSLPPDSGSILId 66
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 389 GANLqigyydQKQAEFKSSKTIlDYVWdQYPLM----------------------------NEKDIR------AVLGRFL 434
Cdd:COG1101 67 GKDV------TKLPEYKRAKYI-GRVF-QDPMMgtapsmtieenlalayrrgkrrglrrglTKKRRElfrellATLGLGL 138
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 446524717 435 fvQDDVKKIINDLSGGEkaRLQLALLM--LQRDNVLILDEPTNHLD 478
Cdd:COG1101 139 --ENRLDTKVGLLSGGQ--RQALSLLMatLTKPKLLLLDEHTAALD 180
|
|
| GlnQ |
COG1126 |
ABC-type polar amino acid transport system, ATPase component [Amino acid transport and ... |
348-375 |
1.30e-05 |
|
ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 440743 [Multi-domain] Cd Length: 239 Bit Score: 46.91 E-value: 1.30e-05
10 20
....*....|....*....|....*...
gi 446524717 348 ISIEVSKGDHIAIIGPNGIGKSTLIKTI 375
Cdd:COG1126 20 ISLDVEKGEVVVIIGPSGSGKSTLLRCI 47
|
|
| cbiO |
PRK13634 |
cobalt transporter ATP-binding subunit; Provisional |
329-501 |
1.32e-05 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237454 [Multi-domain] Cd Length: 290 Bit Score: 47.32 E-value: 1.32e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 329 DVMHVKNLEIGYQTAITKPISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITFGANLQIGYYDQKQaeFKSSK 408
Cdd:PRK13634 7 KVEHRYQYKTPFERRALYDVNVSIPSGSYVAIIGHTGSGKSTLLQHLNGLLQPTSGTVTIGERVITAGKKNKK--LKPLR 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 409 TILDYVWdQYP---LMNE---KDIRAVLGRFLFVQDD----VKKIIN--------------DLSGGEKARLQLALLMLQR 464
Cdd:PRK13634 85 KKVGIVF-QFPehqLFEEtveKDICFGPMNFGVSEEDakqkAREMIElvglpeellarspfELSGGQMRRVAIAGVLAME 163
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 446524717 465 DNVLILDEPTNHLD-IDSKEMLEQALQ-HFEG--TILFVSH 501
Cdd:PRK13634 164 PEVLVLDEPTAGLDpKGRKEMMEMFYKlHKEKglTTVLVTH 204
|
|
| ABCG_PDR_domain1 |
cd03233 |
First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette ... |
9-202 |
1.35e-05 |
|
First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213200 [Multi-domain] Cd Length: 202 Bit Score: 46.49 E-value: 1.35e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 9 ISKSFDGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVEnydSGNVSKIKNLKLGYLTqqmtlnsnatvfeemS 88
Cdd:cd03233 13 TGKGRSKIPILKDFSGVVKPGEMVLVLGRPGSGCSTLLKALANRT---EGNVSVEGDIHYNGIP---------------Y 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 89 KPFEHIKRMESLIKEETDWlskhandydsdtyktHMSryeslsnqfeQLegyqyeskikTVLHGLNFSEE-DFNKPINDF 167
Cdd:cd03233 75 KEFAEKYPGEIIYVSEEDV---------------HFP----------TL----------TVRETLDFALRcKGNEFVRGI 119
|
170 180 190
....*....|....*....|....*....|....*
gi 446524717 168 SGGQKTRLSLAQMLLNEPDLLLLDEPTNHLDLETT 202
Cdd:cd03233 120 SGGERKRVSIAEALVSRASVLCWDNSTRGLDSSTA 154
|
|
| ABC_ThiQ_thiamine_transporter |
cd03298 |
ATP-binding cassette domain of the thiamine transport system; Part of the ... |
21-61 |
1.40e-05 |
|
ATP-binding cassette domain of the thiamine transport system; Part of the binding-protein-dependent transport system tbpA-thiPQ for thiamine and TPP. Probably responsible for the translocation of thiamine across the membrane. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213265 [Multi-domain] Cd Length: 211 Bit Score: 46.72 E-value: 1.40e-05
10 20 30 40
....*....|....*....|....*....|....*....|.
gi 446524717 21 DVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNVS 61
Cdd:cd03298 16 HFDLTFAQGEITAIVGPSGSGKSTLLNLIAGFETPQSGRVL 56
|
|
| cbiO |
PRK13635 |
energy-coupling factor ABC transporter ATP-binding protein; |
3-222 |
1.47e-05 |
|
energy-coupling factor ABC transporter ATP-binding protein;
Pssm-ID: 184195 [Multi-domain] Cd Length: 279 Bit Score: 47.32 E-value: 1.47e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 3 LLQLNHISKSFDGED--IFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNVsKIKNLKLgyltqqmtlnSN 80
Cdd:PRK13635 5 IIRVEHISFRYPDAAtyALKDVSFSVYEGEWVAIVGHNGSGKSTLAKLLNGLLLPEAGTI-TVGGMVL----------SE 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 81 ATVFEemskpfehIKRMESLIKEETDwlskhaNDYDSDTYKTHMSRyeSLSNQfeqleGYQYESKIKTVLHGLN-FSEED 159
Cdd:PRK13635 74 ETVWD--------VRRQVGMVFQNPD------NQFVGATVQDDVAF--GLENI-----GVPREEMVERVDQALRqVGMED 132
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446524717 160 F-NKPINDFSGGQKTRLSLAQMLLNEPDLLLLDEPTNHLD-------LETTKWLEDYlryfKGAIVI-ISHD 222
Cdd:PRK13635 133 FlNREPHRLSGGQKQRVAIAGVLALQPDIIILDEATSMLDprgrrevLETVRQLKEQ----KGITVLsITHD 200
|
|
| ABC_sbcCD |
cd03279 |
ATP-binding cassette domain of sbcCD; SbcCD and other Mre11/Rad50 (MR) complexes are ... |
336-513 |
1.76e-05 |
|
ATP-binding cassette domain of sbcCD; SbcCD and other Mre11/Rad50 (MR) complexes are implicated in the metabolism of DNA ends. They cleave ends sealed by hairpin structures and are thought to play a role in removing protein bound to DNA termini.
Pssm-ID: 213246 [Multi-domain] Cd Length: 213 Bit Score: 46.11 E-value: 1.76e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 336 LEIGYQTAITKPISIEVSKGDHI---AIIGPNGIGKSTLIKTIAnqqKALNGYiTFGANLQIGYYDQKQAEFKSSKTILD 412
Cdd:cd03279 6 LELKNFGPFREEQVIDFTGLDNNglfLICGPTGAGKSTILDAIT---YALYGK-TPRYGRQENLRSVFAPGEDTAEVSFT 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 413 -------YVWDQYPLMNEKD-IRAVL---GRF-LFVQDDVKkiinDLSGGEKARLQLAL------LMLQRDNV----LIL 470
Cdd:cd03279 82 fqlggkkYRVERSRGLDYDQfTRIVLlpqGEFdRFLARPVS----TLSGGETFLASLSLalalseVLQNRGGArleaLFI 157
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 446524717 471 DEPTNHLDIDSKEMLEQALQHFEGT---ILFVSHDRYFINQLANKV 513
Cdd:cd03279 158 DEGFGTLDPEALEAVATALELIRTEnrmVGVISHVEELKERIPQRL 203
|
|
| cbiO |
PRK13650 |
energy-coupling factor transporter ATPase; |
329-502 |
1.95e-05 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184209 [Multi-domain] Cd Length: 279 Bit Score: 46.65 E-value: 1.95e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 329 DVMHVKNLEIGYQTAITKP----ISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITFGANL-----------Q 393
Cdd:PRK13650 3 NIIEVKNLTFKYKEDQEKYtlndVSFHVKQGEWLSIIGHNGSGKSTTVRLIDGLLEAESGQIIIDGDLlteenvwdirhK 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 394 IGYYDQKQAEFKSSKTILDYV-------WDQYPLMNEKDIRAVlgRFLFVQDDVKKIINDLSGGEKARLQLALLMLQRDN 466
Cdd:PRK13650 83 IGMVFQNPDNQFVGATVEDDVafglenkGIPHEEMKERVNEAL--ELVGMQDFKEREPARLSGGQKQRVAIAGAVAMRPK 160
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 446524717 467 VLILDEPTNHLDIDSKEMLEQAL----QHFEGTILFVSHD 502
Cdd:PRK13650 161 IIILDEATSMLDPEGRLELIKTIkgirDDYQMTVISITHD 200
|
|
| CFTR_protein |
TIGR01271 |
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ... |
14-223 |
1.96e-05 |
|
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]
Pssm-ID: 273530 [Multi-domain] Cd Length: 1490 Bit Score: 47.98 E-value: 1.96e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 14 DGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDsGNVskiknlklgyltQQMTLNSNATVFEEMSKPFEH 93
Cdd:TIGR01271 1230 AGRAVLQDLSFSVEGGQRVGLLGRTGSGKSTLLSALLRLLSTE-GEI------------QIDGVSWNSVTLQTWRKAFGV 1296
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 94 IKRMESLIkeetdwlskhandydSDTYKTHMSRYESLSNQ--FEQLEGYQYESKIKTVLHGLNFSEEDFNKPIndfSGGQ 171
Cdd:TIGR01271 1297 IPQKVFIF---------------SGTFRKNLDPYEQWSDEeiWKVAEEVGLKSVIEQFPDKLDFVLVDGGYVL---SNGH 1358
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 446524717 172 KTRLSLAQMLLNEPDLLLLDEPTNHLDLETTKWLEDYLRY-FKGAIVIISHDR 223
Cdd:TIGR01271 1359 KQLMCLARSILSKAKILLLDEPSAHLDPVTLQIIRKTLKQsFSNCTVILSEHR 1411
|
|
| MRP_assoc_pro |
TIGR00957 |
multi drug resistance-associated protein (MRP); This model describes multi drug ... |
348-534 |
2.11e-05 |
|
multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]
Pssm-ID: 188098 [Multi-domain] Cd Length: 1522 Bit Score: 48.02 E-value: 2.11e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 348 ISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITFGANLQigyYDQKQAEFKSSkTILDYVWDQYPLmNEKDIR 427
Cdd:TIGR00957 657 ITFSIPEGALVAVVGQVGCGKSSLLSALLAEMDKVEGHVHMKGSVA---YVPQQAWIQND-SLRENILFGKAL-NEKYYQ 731
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 428 AVLGRFLFVQD-------DVKKI----INdLSGGEKARLQLALLMLQRDNVLILDEPTNHLDID-SKEMLEQALQHfEG- 494
Cdd:TIGR00957 732 QVLEACALLPDleilpsgDRTEIgekgVN-LSGGQKQRVSLARAVYSNADIYLFDDPLSAVDAHvGKHIFEHVIGP-EGv 809
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 446524717 495 ----TILFVSHDRYFINQLAnkvFDLTIDGGKMY-LGDYQYYIEK 534
Cdd:TIGR00957 810 lknkTRILVTHGISYLPQVD---VIIVMSGGKISeMGSYQELLQR 851
|
|
| PRK03695 |
PRK03695 |
vitamin B12-transporter ATPase; Provisional |
4-222 |
2.27e-05 |
|
vitamin B12-transporter ATPase; Provisional
Pssm-ID: 235150 [Multi-domain] Cd Length: 248 Bit Score: 46.46 E-value: 2.27e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 4 LQLNHISKSfdgeDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYdSGNVS-KIKNLKL----------GYLT 72
Cdd:PRK03695 1 MQLNDVAVS----TRLGPLSAEVRAGEILHLVGPNGAGKSTLLARMAGLLPG-SGSIQfAGQPLEAwsaaelarhrAYLS 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 73 QQMTLNSNATVFEEMSkpfehikrmeslikeetdwLSKHAndydsdtyKTHMSRYESLSNQFEQLegYQYESKiktvLHg 152
Cdd:PRK03695 76 QQQTPPFAMPVFQYLT-------------------LHQPD--------KTRTEAVASALNEVAEA--LGLDDK----LG- 121
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 153 lnfseedfnKPINDFSGGQKTRLSLA----QMLLNEPDLLLL---DEPTNHLDLETTKWLEDYLRYF---KGAIVIISHD 222
Cdd:PRK03695 122 ---------RSVNQLSGGEWQRVRLAavvlQVWPDINPAGQLlllDEPMNSLDVAQQAALDRLLSELcqqGIAVVMSSHD 192
|
|
| glnQ |
PRK09493 |
glutamine ABC transporter ATP-binding protein GlnQ; |
3-200 |
2.35e-05 |
|
glutamine ABC transporter ATP-binding protein GlnQ;
Pssm-ID: 181906 [Multi-domain] Cd Length: 240 Bit Score: 46.24 E-value: 2.35e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 3 LLQLNHISKSFDGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNVskiknlklgyLTQQMTLNSNAT 82
Cdd:PRK09493 1 MIEFKNVSKHFGPTQVLHNIDLNIDQGEVVVIIGPSGSGKSTLLRCINKLEEITSGDL----------IVDGLKVNDPKV 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 83 VfeemskpfehikrmESLIKEETDWLSKHANDYdsdtykTHMSRYESLSNQFEQLEGY---QYESKIKTVLHGLNFSEED 159
Cdd:PRK09493 71 D--------------ERLIRQEAGMVFQQFYLF------PHLTALENVMFGPLRVRGAskeEAEKQARELLAKVGLAERA 130
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 446524717 160 FNKPiNDFSGGQKTRLSLAQMLLNEPDLLLLDEPTNHLDLE 200
Cdd:PRK09493 131 HHYP-SELSGGQQQRVAIARALAVKPKLMLFDEPTSALDPE 170
|
|
| BtuD |
COG4138 |
ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism]; ... |
22-85 |
2.48e-05 |
|
ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism];
Pssm-ID: 443313 [Multi-domain] Cd Length: 248 Bit Score: 46.37 E-value: 2.48e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446524717 22 VDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYdSGNV-------SKIKNLKL----GYLTQQMTLNSNATVFE 85
Cdd:COG4138 15 ISAQVNAGELIHLIGPNGAGKSTLLARMAGLLPG-QGEIllngrplSDWSAAELarhrAYLSQQQSPPFAMPVFQ 88
|
|
| PRK15079 |
PRK15079 |
oligopeptide ABC transporter ATP-binding protein OppF; Provisional |
348-526 |
2.58e-05 |
|
oligopeptide ABC transporter ATP-binding protein OppF; Provisional
Pssm-ID: 185037 [Multi-domain] Cd Length: 331 Bit Score: 46.62 E-value: 2.58e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 348 ISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITF-GANLQigyyDQKQAEFKSSKTILDYVWdQYPL------ 420
Cdd:PRK15079 40 VTLRLYEGETLGVVGESGCGKSTFARAIIGLVKATDGEVAWlGKDLL----GMKDDEWRAVRSDIQMIF-QDPLaslnpr 114
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 421 MNEKDIRAVLGRFLF-------VQDDVKKI----------IN----DLSGGEKARLQLALLMLQRDNVLILDEPTNHLDI 479
Cdd:PRK15079 115 MTIGEIIAEPLRTYHpklsrqeVKDRVKAMmlkvgllpnlINryphEFSGGQCQRIGIARALILEPKLIICDEPVSALDV 194
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 446524717 480 DSKEM---LEQALQHFEG-TILFVSHDRYFINQLANKVFdltidggKMYLG 526
Cdd:PRK15079 195 SIQAQvvnLLQQLQREMGlSLIFIAHDLAVVKHISDRVL-------VMYLG 238
|
|
| YnjD |
COG4136 |
ABC-type uncharacterized transport system YnjBCD, ATPase component [General function ... |
331-502 |
2.66e-05 |
|
ABC-type uncharacterized transport system YnjBCD, ATPase component [General function prediction only];
Pssm-ID: 443311 [Multi-domain] Cd Length: 211 Bit Score: 45.55 E-value: 2.66e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 331 MHVKNLEIGY-QTAITKPISIEVSKGDHIAIIGPNGIGKSTLIKTIAnqqkalngyitfGAnlqigyydqKQAEFKSSKT 409
Cdd:COG4136 2 LSLENLTITLgGRPLLAPLSLTVAPGEILTLMGPSGSGKSTLLAAIA------------GT---------LSPAFSASGE 60
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 410 ILdyvwdqyplMNEKDIRAV------LGrFLFvQDDV------------------------KKIIND------------- 446
Cdd:COG4136 61 VL---------LNGRRLTALpaeqrrIG-ILF-QDDLlfphlsvgenlafalpptigraqrRARVEQaleeaglagfadr 129
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446524717 447 ----LSGGEKARLQLALLMLQRDNVLILDEPTNHLDID-SKEMLEQ---ALQHFEGTILFVSHD 502
Cdd:COG4136 130 dpatLSGGQRARVALLRALLAEPRALLLDEPFSKLDAAlRAQFREFvfeQIRQRGIPALLVTHD 193
|
|
| PstB |
COG1117 |
ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism]; ... |
323-501 |
2.70e-05 |
|
ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440734 [Multi-domain] Cd Length: 258 Bit Score: 46.18 E-value: 2.70e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 323 DRNTGNDVMHVKNLEIGY--QTAItKPISIEVSKGDHIAIIGPNGIGKSTLIKT-------IANQQkaLNGYITF-GANL 392
Cdd:COG1117 4 PASTLEPKIEVRNLNVYYgdKQAL-KDINLDIPENKVTALIGPSGCGKSTLLRClnrmndlIPGAR--VEGEILLdGEDI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 393 ------------QIGYYDQKQAEFksSKTILDYVwdQYPL-MNEKDIRAVL---------GRFLFvqDDVKKIIND---- 446
Cdd:COG1117 81 ydpdvdvvelrrRVGMVFQKPNPF--PKSIYDNV--AYGLrLHGIKSKSELdeiveeslrKAALW--DEVKDRLKKsalg 154
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 447 LSGGEKARLQLA-LLMLQRDnVLILDEPTNHLDIDSKEMLEQAL----QHFegTILFVSH 501
Cdd:COG1117 155 LSGGQQQRLCIArALAVEPE-VLLMDEPTSALDPISTAKIEELIlelkKDY--TIVIVTH 211
|
|
| ntrCD |
TIGR01184 |
nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits ... |
21-222 |
2.98e-05 |
|
nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits of nitrate transport in bacteria and archaea. This protein belongs to the ATP-binding cassette (ABC) superfamily. It is thought that the two subunits encoded by ntrC and ntrD form the binding surface for interaction with ATP. This model is restricted in identifying ATP binding subunit associated with the nitrate transport. Nitrate assimilation is aided by other proteins derived from the operon which among others include products of ntrA - a regulatory protein; ntrB - a hydropbobic transmembrane permease and narB - a reductase. [Transport and binding proteins, Anions, Transport and binding proteins, Other]
Pssm-ID: 130252 [Multi-domain] Cd Length: 230 Bit Score: 45.92 E-value: 2.98e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 21 DVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNVSkiknLKLGYLTQ----QMTLNSNATVFEemskpfehikr 96
Cdd:TIGR01184 3 GVNLTIQQGEFISLIGHSGCGKSTLLNLISGLAQPTSGGVI----LEGKQITEpgpdRMVVFQNYSLLP----------- 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 97 meslikeetdWLSKHANDYDS-DTYKTHMSRYESLSNQFEQLEgyqyeskiktvLHGLNFSEEdfnKPINDFSGGQKTRL 175
Cdd:TIGR01184 68 ----------WLTVRENIALAvDRVLPDLSKSERRAIVEEHIA-----------LVGLTEAAD---KRPGQLSGGMKQRV 123
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 446524717 176 SLAQMLLNEPDLLLLDEPTNHLDLETTKWLEDYLRYF----KGAIVIISHD 222
Cdd:TIGR01184 124 AIARALSIRPKVLLLDEPFGALDALTRGNLQEELMQIweehRVTVLMVTHD 174
|
|
| cbiO |
PRK13632 |
cobalt transporter ATP-binding subunit; Provisional |
325-523 |
3.51e-05 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237452 [Multi-domain] Cd Length: 271 Bit Score: 46.14 E-value: 3.51e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 325 NTGNDVM-HVKNLEIGYQTA---ITKPISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGyitfgaNLQIGYYDQK 400
Cdd:PRK13632 1 IKNKSVMiKVENVSFSYPNSennALKNVSFEINEGEYVAILGHNGSGKSTISKILTGLLKPQSG------EIKIDGITIS 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 401 QAEFKSSKTILDYVWdQYP------LMNEKDIRAVLGRFLFVQDDVKKIIND-----------------LSGGEKARLQL 457
Cdd:PRK13632 75 KENLKEIRKKIGIIF-QNPdnqfigATVEDDIAFGLENKKVPPKKMKDIIDDlakkvgmedyldkepqnLSGGQKQRVAI 153
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446524717 458 ALLMLQRDNVLILDEPTNHLD----IDSKEMLEQALQHFEGTILFVSHDryfINQ--LANKVfdLTIDGGKM 523
Cdd:PRK13632 154 ASVLALNPEIIIFDESTSMLDpkgkREIKKIMVDLRKTRKKTLISITHD---MDEaiLADKV--IVFSEGKL 220
|
|
| PTZ00265 |
PTZ00265 |
multidrug resistance protein (mdr1); Provisional |
17-221 |
3.53e-05 |
|
multidrug resistance protein (mdr1); Provisional
Pssm-ID: 240339 [Multi-domain] Cd Length: 1466 Bit Score: 47.33 E-value: 3.53e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 17 DIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVEN--------YDSGNVSKIkNL-----KLGYLTQQMTLNSNaTV 83
Cdd:PTZ00265 399 EIYKDLNFTLTEGKTYAFVGESGCGKSTILKLIERLYDptegdiiiNDSHNLKDI-NLkwwrsKIGVVSQDPLLFSN-SI 476
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 84 FEEMSKPFEHIKRMESLikeeTDWLSKHANDYDSDTYKTHMSR------YESLSNQFEQLEGYQYESKIKTVLHG--LNF 155
Cdd:PTZ00265 477 KNNIKYSLYSLKDLEAL----SNYYNEDGNDSQENKNKRNSCRakcagdLNDMSNTTDSNELIEMRKNYQTIKDSevVDV 552
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 156 SEE----DFNKPIND------------FSGGQKTRLSLAQMLLNEPDLLLLDEPTNHLDLETTKWLEDYLRYFKG----A 215
Cdd:PTZ00265 553 SKKvlihDFVSALPDkyetlvgsnaskLSGGQKQRISIARAIIRNPKILILDEATSSLDNKSEYLVQKTINNLKGnenrI 632
|
....*.
gi 446524717 216 IVIISH 221
Cdd:PTZ00265 633 TIIIAH 638
|
|
| ABCC_SUR1_N |
cd03290 |
ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The ... |
348-501 |
3.93e-05 |
|
ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The sulfonylurea receptor SUR is an ATP transporter of the ABCC/MRP family with tandem ATPase binding domains. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.
Pssm-ID: 213257 [Multi-domain] Cd Length: 218 Bit Score: 45.40 E-value: 3.93e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 348 ISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITFGANLQ---------------IGYYDQKqaEFKSSKTILD 412
Cdd:cd03290 20 INIRIPTGQLTMIVGQVGCGKSSLLLAILGEMQTLEGKVHWSNKNEsepsfeatrsrnrysVAYAAQK--PWLLNATVEE 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 413 YVWDQYPLmNEKDIRAVLGRfLFVQDDV------------KKIINdLSGGEKARLQLALLMLQRDNVLILDEPTNHLDID 480
Cdd:cd03290 98 NITFGSPF-NKQRYKAVTDA-CSLQPDIdllpfgdqteigERGIN-LSGGQRQRICVARALYQNTNIVFLDDPFSALDIH 174
|
170 180
....*....|....*....|....*.
gi 446524717 481 SKEMLEQA-----LQHFEGTILFVSH 501
Cdd:cd03290 175 LSDHLMQEgilkfLQDDKRTLVLVTH 200
|
|
| fbpC |
PRK11432 |
ferric ABC transporter ATP-binding protein; |
4-60 |
4.15e-05 |
|
ferric ABC transporter ATP-binding protein;
Pssm-ID: 183133 [Multi-domain] Cd Length: 351 Bit Score: 46.25 E-value: 4.15e-05
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*..
gi 446524717 4 LQLNHISKSFDGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNV 60
Cdd:PRK11432 7 VVLKNITKRFGSNTVIDNLNLTIKQGTMVTLLGPSGCGKTTVLRLVAGLEKPTEGQI 63
|
|
| PRK15079 |
PRK15079 |
oligopeptide ABC transporter ATP-binding protein OppF; Provisional |
11-258 |
4.19e-05 |
|
oligopeptide ABC transporter ATP-binding protein OppF; Provisional
Pssm-ID: 185037 [Multi-domain] Cd Length: 331 Bit Score: 46.24 E-value: 4.19e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 11 KSFDGediftdVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNVSKIKNLKLGYLTQQM--------------- 75
Cdd:PRK15079 35 KAVDG------VTLRLYEGETLGVVGESGCGKSTFARAIIGLVKATDGEVAWLGKDLLGMKDDEWravrsdiqmifqdpl 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 76 -TLNSNATVFEEMSKPFEhikrmeslikeetdwlskhandydsdTYKTHMSRYEslsnqfeqlegyqYESKIKTVLHGLN 154
Cdd:PRK15079 109 aSLNPRMTIGEIIAEPLR--------------------------TYHPKLSRQE-------------VKDRVKAMMLKVG 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 155 FSEEDFNKPINDFSGGQKTRLSLAQMLLNEPDLLLLDEPTNHLDL----ETTKWLEDYLRYFKGAIVIISHDRyfldKIV 230
Cdd:PRK15079 150 LLPNLINRYPHEFSGGQCQRIGIARALILEPKLIICDEPVSALDVsiqaQVVNLLQQLQREMGLSLIFIAHDL----AVV 225
|
250 260
....*....|....*....|....*...
gi 446524717 231 TQIYDVALgdvKRYVGNYEEFIQQRDLY 258
Cdd:PRK15079 226 KHISDRVL---VMYLGHAVELGTYDEVY 250
|
|
| MglA |
COG1129 |
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; |
348-501 |
4.45e-05 |
|
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440745 [Multi-domain] Cd Length: 497 Bit Score: 46.55 E-value: 4.45e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 348 ISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITFganlqigyyDQKQAEFKSSK------------------- 408
Cdd:COG1129 23 VSLELRPGEVHALLGENGAGKSTLMKILSGVYQPDSGEILL---------DGEPVRFRSPRdaqaagiaiihqelnlvpn 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 409 -TILDYVW-DQYP----LMNEKDIR----AVLGRfLFVQDDVKKIINDLSGGEK-----ARlqlALLmlqRD-NVLILDE 472
Cdd:COG1129 94 lSVAENIFlGREPrrggLIDWRAMRrrarELLAR-LGLDIDPDTPVGDLSVAQQqlveiAR---ALS---RDaRVLILDE 166
|
170 180 190
....*....|....*....|....*....|..
gi 446524717 473 PTNHLDIDSKEMLEQALQHF--EG-TILFVSH 501
Cdd:COG1129 167 PTASLTEREVERLFRIIRRLkaQGvAIIYISH 198
|
|
| oppD |
PRK09473 |
oligopeptide transporter ATP-binding component; Provisional |
1-260 |
4.51e-05 |
|
oligopeptide transporter ATP-binding component; Provisional
Pssm-ID: 181888 [Multi-domain] Cd Length: 330 Bit Score: 45.87 E-value: 4.51e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 1 MILLQLNHISKSFDGED-IFT---DVDFEVKTGERIGIVGRNGAGKS----TLMKIIAG---VENYDSGNVSKIKNLKLG 69
Cdd:PRK09473 10 DALLDVKDLRVTFSTPDgDVTavnDLNFSLRAGETLGIVGESGSGKSqtafALMGLLAAngrIGGSATFNGREILNLPEK 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 70 YLtqqmtlnsNATVFEEMSKPFEhiKRMESL-----IKEE-TDWLSKHandydsdtykTHMSRYESlsnqfeqlegyqYE 143
Cdd:PRK09473 90 EL--------NKLRAEQISMIFQ--DPMTSLnpymrVGEQlMEVLMLH----------KGMSKAEA------------FE 137
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 144 SKIKtVLHGLNFSEEdfNKPIN----DFSGGQKTRLSLAQMLLNEPDLLLLDEPTNHLDL----ETTKWLEDYLRYFKGA 215
Cdd:PRK09473 138 ESVR-MLDAVKMPEA--RKRMKmyphEFSGGMRQRVMIAMALLCRPKLLIADEPTTALDVtvqaQIMTLLNELKREFNTA 214
|
250 260 270 280
....*....|....*....|....*....|....*....|....*
gi 446524717 216 IVIISHDRyfldKIVTQIYDVALgdvKRYVGNYEEFIQQRDLYYQ 260
Cdd:PRK09473 215 IIMITHDL----GVVAGICDKVL---VMYAGRTMEYGNARDVFYQ 252
|
|
| PLN03211 |
PLN03211 |
ABC transporter G-25; Provisional |
352-489 |
4.72e-05 |
|
ABC transporter G-25; Provisional
Pssm-ID: 215634 [Multi-domain] Cd Length: 659 Bit Score: 46.41 E-value: 4.72e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 352 VSKGDHIAIIGPNGIGKSTLIKTIAN--QQKALNGYItFGANLQIGYYDQKQAEFKSSKTILdyvwdqYPLMN--EKDIR 427
Cdd:PLN03211 91 ASPGEILAVLGPSGSGKSTLLNALAGriQGNNFTGTI-LANNRKPTKQILKRTGFVTQDDIL------YPHLTvrETLVF 163
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 428 AVLGRF---------LFVQDDV---------------KKIINDLSGGEKARLQLALLMLQRDNVLILDEPTNHLDIDSKE 483
Cdd:PLN03211 164 CSLLRLpksltkqekILVAESViselgltkcentiigNSFIRGISGGERKRVSIAHEMLINPSLLILDEPTSGLDATAAY 243
|
....*.
gi 446524717 484 MLEQAL 489
Cdd:PLN03211 244 RLVLTL 249
|
|
| ABC_SMC_head |
cd03239 |
The SMC head domain belongs to the ATP-binding cassette superfamily; The structural ... |
359-483 |
4.73e-05 |
|
The SMC head domain belongs to the ATP-binding cassette superfamily; The structural maintenance of chromosomes (SMC) proteins are essential for successful chromosome transmission during replication and segregation of the genome in all organisms. SMCs are generally present as single proteins in bacteria, and as at least six distinct proteins in eukaryotes. The proteins range in size from approximately 110 to 170 kDa, and each has five distinct domains: amino- and carboxy-terminal globular domains, which contain sequences characteristic of ATPases, two coiled-coil regions separating the terminal domains , and a central flexible hinge. SMC proteins function together with other proteins in a range of chromosomal transactions, including chromosome condensation, sister-chromatid cohesion, recombination, DNA repair, and epigenetic silencing of gene expression.
Pssm-ID: 213206 [Multi-domain] Cd Length: 178 Bit Score: 44.61 E-value: 4.73e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 359 AIIGPNGIGKSTLIKTIanqqkalngyitfganlQIGYYDQKQAEFKSSKTILDYVWDQyPLMNEKDIRAVL--GRFLFV 436
Cdd:cd03239 26 AIVGPNGSGKSNIVDAI-----------------CFVLGGKAAKLRRGSLLFLAGGGVK-AGINSASVEITFdkSYFLVL 87
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 446524717 437 QDDVKKIindLSGGEKARLQLALLM----LQRDNVLILDEPTNHLDIDSKE 483
Cdd:cd03239 88 QGKVEQI---LSGGEKSLSALALIFalqeIKPSPFYVLDEIDAALDPTNRR 135
|
|
| PvdE |
COG4615 |
ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion ... |
4-51 |
5.31e-05 |
|
ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion transport and metabolism];
Pssm-ID: 443659 [Multi-domain] Cd Length: 547 Bit Score: 46.33 E-value: 5.31e-05
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 446524717 4 LQLNHISKSFDGEDI---FT--DVDFEVKTGERIGIVGRNGAGKSTLMKIIAG 51
Cdd:COG4615 328 LELRGVTYRYPGEDGdegFTlgPIDLTIRRGELVFIVGGNGSGKSTLAKLLTG 380
|
|
| PRK10584 |
PRK10584 |
putative ABC transporter ATP-binding protein YbbA; Provisional |
340-510 |
5.33e-05 |
|
putative ABC transporter ATP-binding protein YbbA; Provisional
Pssm-ID: 182569 [Multi-domain] Cd Length: 228 Bit Score: 45.16 E-value: 5.33e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 340 YQTAITKPISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITF-GANLQIGYYDQKQA--------EFKSSKTI 410
Cdd:PRK10584 21 HELSILTGVELVVKRGETIALIGESGSGKSTLLAILAGLDDGSSGEVSLvGQPLHQMDEEARAKlrakhvgfVFQSFMLI 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 411 -----LDYVwdQYPLM----NEKDIR---AVLGRFLFVQDDVKKIINDLSGGEKARLQLALLMLQRDNVLILDEPTNHLD 478
Cdd:PRK10584 101 ptlnaLENV--ELPALlrgeSSRQSRngaKALLEQLGLGKRLDHLPAQLSGGEQQRVALARAFNGRPDVLFADEPTGNLD 178
|
170 180 190
....*....|....*....|....*....|....*.
gi 446524717 479 IDSKEMLEQAL----QHFEGTILFVSHDryfiNQLA 510
Cdd:PRK10584 179 RQTGDKIADLLfslnREHGTTLILVTHD----LQLA 210
|
|
| PRK10535 |
PRK10535 |
macrolide ABC transporter ATP-binding protein/permease MacB; |
3-58 |
5.41e-05 |
|
macrolide ABC transporter ATP-binding protein/permease MacB;
Pssm-ID: 182528 [Multi-domain] Cd Length: 648 Bit Score: 46.26 E-value: 5.41e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 3 LLQLNHISKSF-DGE---DIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSG 58
Cdd:PRK10535 4 LLELKDIRRSYpSGEeqvEVLKGISLDIYAGEMVAIVGASGSGKSTLMNILGCLDKPTSG 63
|
|
| sufC |
PRK09580 |
cysteine desulfurase ATPase component; Reviewed |
330-501 |
5.74e-05 |
|
cysteine desulfurase ATPase component; Reviewed
Pssm-ID: 181965 [Multi-domain] Cd Length: 248 Bit Score: 45.17 E-value: 5.74e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 330 VMHVKNLEIGYQ-TAITKPISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQ--KALNGYITF-GANLQigyydQKQAEFK 405
Cdd:PRK09580 1 MLSIKDLHVSVEdKAILRGLNLEVRPGEVHAIMGPNGSGKSTLSATLAGREdyEVTGGTVEFkGKDLL-----ELSPEDR 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 406 SSKTIldYVWDQYP---------LMNEKDIRAV--------LGRFLF---VQDDVK--KIINDL---------SGGEKAR 454
Cdd:PRK09580 76 AGEGI--FMAFQYPveipgvsnqFFLQTALNAVrsyrgqepLDRFDFqdlMEEKIAllKMPEDLltrsvnvgfSGGEKKR 153
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 446524717 455 ---LQLALLmlqRDNVLILDEPTNHLDIDSKEMLEQ---ALQHFEGTILFVSH 501
Cdd:PRK09580 154 ndiLQMAVL---EPELCILDESDSGLDIDALKIVADgvnSLRDGKRSFIIVTH 203
|
|
| PRK10938 |
PRK10938 |
putative molybdenum transport ATP-binding protein ModF; Provisional |
3-51 |
5.84e-05 |
|
putative molybdenum transport ATP-binding protein ModF; Provisional
Pssm-ID: 182852 [Multi-domain] Cd Length: 490 Bit Score: 46.16 E-value: 5.84e-05
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 446524717 3 LLQLNHISKSFDGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAG 51
Cdd:PRK10938 260 RIVLNNGVVSYNDRPILHNLSWQVNPGEHWQIVGPNGAGKSTLLSLITG 308
|
|
| cbiO |
PRK13650 |
energy-coupling factor transporter ATPase; |
21-60 |
6.08e-05 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184209 [Multi-domain] Cd Length: 279 Bit Score: 45.11 E-value: 6.08e-05
10 20 30 40
....*....|....*....|....*....|....*....|
gi 446524717 21 DVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNV 60
Cdd:PRK13650 25 DVSFHVKQGEWLSIIGHNGSGKSTTVRLIDGLLEAESGQI 64
|
|
| AbcC |
COG1135 |
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism]; |
346-478 |
6.30e-05 |
|
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 440750 [Multi-domain] Cd Length: 339 Bit Score: 45.45 E-value: 6.30e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 346 KPISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITF-GANL-------------QIGYYDQkQAEFKSSKTIL 411
Cdd:COG1135 22 DDVSLTIEKGEIFGIIGYSGAGKSTLIRCINLLERPTSGSVLVdGVDLtalserelraarrKIGMIFQ-HFNLLSSRTVA 100
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446524717 412 DYVwdQYPL----MNEKDIRAVLGRFL-FV--QDDVKKIINDLSGGEKARLQ----LALlmlqRDNVLILDEPTNHLD 478
Cdd:COG1135 101 ENV--ALPLeiagVPKAEIRKRVAELLeLVglSDKADAYPSQLSGGQKQRVGiaraLAN----NPKVLLCDEATSALD 172
|
|
| PRK13540 |
PRK13540 |
cytochrome c biogenesis protein CcmA; Provisional |
6-60 |
6.81e-05 |
|
cytochrome c biogenesis protein CcmA; Provisional
Pssm-ID: 184127 [Multi-domain] Cd Length: 200 Bit Score: 44.17 E-value: 6.81e-05
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*..
gi 446524717 6 LNHISKSFDGED--IFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNV 60
Cdd:PRK13540 2 LDVIELDFDYHDqpLLQQISFHLPAGGLLHLKGSNGAGKTTLLKLIAGLLNPEKGEI 58
|
|
| cbiO |
PRK13645 |
energy-coupling factor transporter ATPase; |
349-513 |
6.95e-05 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184204 [Multi-domain] Cd Length: 289 Bit Score: 45.00 E-value: 6.95e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 349 SIEVSKGDHIAIIGPNGIGKSTLIK-----TIANQQKALNGYITFGANLQigyydqKQAEFKSSKTILDYVWD--QYPLM 421
Cdd:PRK13645 31 SLTFKKNKVTCVIGTTGSGKSTMIQltnglIISETGQTIVGDYAIPANLK------KIKEVKRLRKEIGLVFQfpEYQLF 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 422 NE---------------------KDIRAVLGRFLFVQDDVKKIINDLSGGEKARLQLALLMLQRDNVLILDEPTNHLDID 480
Cdd:PRK13645 105 QEtiekdiafgpvnlgenkqeayKKVPELLKLVQLPEDYVKRSPFELSGGQKRRVALAGIIAMDGNTLVLDEPTGGLDPK 184
|
170 180 190
....*....|....*....|....*....|....*..
gi 446524717 481 SKE----MLEQALQHFEGTILFVSHDRYFINQLANKV 513
Cdd:PRK13645 185 GEEdfinLFERLNKEYKKRIIMVTHNMDQVLRIADEV 221
|
|
| hmuV |
PRK13547 |
heme ABC transporter ATP-binding protein; |
3-51 |
7.31e-05 |
|
heme ABC transporter ATP-binding protein;
Pssm-ID: 184132 [Multi-domain] Cd Length: 272 Bit Score: 44.82 E-value: 7.31e-05
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 446524717 3 LLQLNHISKSFDGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAG 51
Cdd:PRK13547 1 MLTADHLHVARRHRAILRDLSLRIEPGRVTALLGRNGAGKSTLLKALAG 49
|
|
| potA |
PRK09452 |
spermidine/putrescine ABC transporter ATP-binding protein PotA; |
342-503 |
7.75e-05 |
|
spermidine/putrescine ABC transporter ATP-binding protein PotA;
Pssm-ID: 236523 [Multi-domain] Cd Length: 375 Bit Score: 45.32 E-value: 7.75e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 342 TAITKPISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITFGanlqigyyDQKQAEFKSSKTILDYVWDQY--- 418
Cdd:PRK09452 27 KEVISNLDLTINNGEFLTLLGPSGCGKTTVLRLIAGFETPDSGRIMLD--------GQDITHVPAENRHVNTVFQSYalf 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 419 PLMN---------------EKDIRA-VLGRFLFVQ--DDVKKIINDLSGGEKARLQLALLMLQRDNVLILDEPTNHLDID 480
Cdd:PRK09452 99 PHMTvfenvafglrmqktpAAEITPrVMEALRMVQleEFAQRKPHQLSGGQQQRVAIARAVVNKPKVLLLDESLSALDYK 178
|
170 180
....*....|....*....|....*..
gi 446524717 481 -SKEM-LE-QALQHFEG-TILFVSHDR 503
Cdd:PRK09452 179 lRKQMqNElKALQRKLGiTFVFVTHDQ 205
|
|
| uvra |
TIGR00630 |
excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of ... |
447-521 |
8.01e-05 |
|
excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of proteins of which all members for which functions are known except the UvrA proteins are involved in the transport of material through membranes. UvrA orthologs are involved in the recognition of DNA damage as a step in nucleotide excision repair. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273184 [Multi-domain] Cd Length: 925 Bit Score: 45.77 E-value: 8.01e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 447 LSGGEKARLQLALLMLQRDN---VLILDEPTN--HLDiDSKEMLE--QALQHFEGTILFVSHDRYFINQlANKVFDLTID 519
Cdd:TIGR00630 830 LSGGEAQRIKLAKELSKRSTgrtLYILDEPTTglHFD-DIKKLLEvlQRLVDKGNTVVVIEHNLDVIKT-ADYIIDLGPE 907
|
..
gi 446524717 520 GG 521
Cdd:TIGR00630 908 GG 909
|
|
| ABC_RNaseL_inhibitor |
cd03222 |
ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a ... |
25-61 |
8.72e-05 |
|
ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins, and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains, which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.
Pssm-ID: 213189 [Multi-domain] Cd Length: 177 Bit Score: 43.71 E-value: 8.72e-05
10 20 30
....*....|....*....|....*....|....*..
gi 446524717 25 EVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNVS 61
Cdd:cd03222 21 VVKEGEVIGIVGPNGTGKTTAVKILAGQLIPNGDNDE 57
|
|
| PRK11176 |
PRK11176 |
lipid A ABC transporter ATP-binding protein/permease MsbA; |
323-501 |
9.24e-05 |
|
lipid A ABC transporter ATP-binding protein/permease MsbA;
Pssm-ID: 183016 [Multi-domain] Cd Length: 582 Bit Score: 45.39 E-value: 9.24e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 323 DRNTGNdvMHVKNLEIGYQTAIT---KPISIEVSKGDHIAIIGPNGIGKSTLiktianqqkalngyitfgANLQIGYYDQ 399
Cdd:PRK11176 336 ERAKGD--IEFRNVTFTYPGKEVpalRNINFKIPAGKTVALVGRSGSGKSTI------------------ANLLTRFYDI 395
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 400 KQAE-FKSSKTILDY-----------VWDQYPLMN-----------------EKDIRAvlGRFLFVQDDVKK-------I 443
Cdd:PRK11176 396 DEGEiLLDGHDLRDYtlaslrnqvalVSQNVHLFNdtianniayarteqysrEQIEEA--ARMAYAMDFINKmdngldtV 473
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446524717 444 IND----LSGGEKARLQLALLMLQRDNVLILDEPTNHLDIDSKEMLEQALQHFEG--TILFVSH 501
Cdd:PRK11176 474 IGEngvlLSGGQRQRIAIARALLRDSPILILDEATSALDTESERAIQAALDELQKnrTSLVIAH 537
|
|
| PRK13541 |
PRK13541 |
cytochrome c biogenesis protein CcmA; Provisional |
34-87 |
1.05e-04 |
|
cytochrome c biogenesis protein CcmA; Provisional
Pssm-ID: 184128 [Multi-domain] Cd Length: 195 Bit Score: 43.71 E-value: 1.05e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446524717 34 IVGRNGAGKSTLMKIIAGVENYDSGNV-------SKIKNLKLGYLTQQMTLNSNATVFEEM 87
Cdd:PRK13541 31 IKGANGCGKSSLLRMIAGIMQPSSGNIyykncniNNIAKPYCTYIGHNLGLKLEMTVFENL 91
|
|
| lolD |
PRK11629 |
lipoprotein-releasing ABC transporter ATP-binding protein LolD; |
330-502 |
1.12e-04 |
|
lipoprotein-releasing ABC transporter ATP-binding protein LolD;
Pssm-ID: 183244 [Multi-domain] Cd Length: 233 Bit Score: 44.04 E-value: 1.12e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 330 VMHVKNLEIGYQ-----TAITKPISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITFGANLQIGYYDQKQAEF 404
Cdd:PRK11629 5 LLQCDNLCKRYQegsvqTDVLHNVSFSIGEGEMMAIVGSSGSGKSTLLHLLGGLDTPTSGDVIFNGQPMSKLSSAAKAEL 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 405 KSSK--------------TILDYVwdQYPLM---------NEK--DIRAVLGrflfVQDDVKKIINDLSGGEKARLQLAL 459
Cdd:PRK11629 85 RNQKlgfiyqfhhllpdfTALENV--AMPLLigkkkpaeiNSRalEMLAAVG----LEHRANHRPSELSGGERQRVAIAR 158
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 446524717 460 LMLQRDNVLILDEPTNHLDI---DSKEMLEQALQHFEGT-ILFVSHD 502
Cdd:PRK11629 159 ALVNNPRLVLADEPTGNLDArnaDSIFQLLGELNRLQGTaFLVVTHD 205
|
|
| cbiO |
PRK13652 |
cobalt transporter ATP-binding subunit; Provisional |
331-514 |
1.15e-04 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 172200 [Multi-domain] Cd Length: 277 Bit Score: 44.41 E-value: 1.15e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 331 MHV---KNLEIGYQTAIT--KPISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITF------GANLQ-----I 394
Cdd:PRK13652 1 MHLietRDLCYSYSGSKEalNNINFIAPRNSRIAVIGPNGAGKSTLFRHFNGILKPTSGSVLIrgepitKENIRevrkfV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 395 GYYDQKQAEFKSSKTI-LDYVWDQYPL-MNEKDIRAVLG---RFLFVQDDVKKIINDLSGGEKARLQLALLMLQRDNVLI 469
Cdd:PRK13652 81 GLVFQNPDDQIFSPTVeQDIAFGPINLgLDEETVAHRVSsalHMLGLEELRDRVPHHLSGGEKKRVAIAGVIAMEPQVLV 160
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 446524717 470 LDEPTNHLDIDSKEMLEQALQHFEG----TILFVSHDRYFINQLANKVF 514
Cdd:PRK13652 161 LDEPTAGLDPQGVKELIDFLNDLPEtygmTVIFSTHQLDLVPEMADYIY 209
|
|
| ABCC_Glucan_exporter_like |
cd03254 |
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan ... |
15-60 |
1.18e-04 |
|
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan exporter ATP-binding protein. In A. tumefaciens cyclic beta-1, 2-glucan must be transported into the periplasmic space to exert its action as a virulence factor. This subfamily belongs to the MRP-like family and is involved in drug, peptide, and lipid export. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains each composed of six transmembrane (TM) helices and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213221 [Multi-domain] Cd Length: 229 Bit Score: 44.14 E-value: 1.18e-04
10 20 30 40
....*....|....*....|....*....|....*....|....*.
gi 446524717 15 GEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNV 60
Cdd:cd03254 15 KKPVLKDINFSIKPGETVAIVGPTGAGKTTLINLLMRFYDPQKGQI 60
|
|
| ATM1 |
COG5265 |
ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components ... |
4-49 |
1.25e-04 |
|
ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444078 [Multi-domain] Cd Length: 605 Bit Score: 45.20 E-value: 1.25e-04
10 20 30 40
....*....|....*....|....*....|....*....|....*..
gi 446524717 4 LQLNHISKSFDGE-DIFTDVDFEVKTGERIGIVGRNGAGKSTLMKII 49
Cdd:COG5265 358 VRFENVSFGYDPErPILKGVSFEVPAGKTVAIVGPSGAGKSTLARLL 404
|
|
| fecE |
PRK11231 |
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE; |
4-224 |
1.41e-04 |
|
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;
Pssm-ID: 183044 [Multi-domain] Cd Length: 255 Bit Score: 43.85 E-value: 1.41e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 4 LQLNHISKSFDGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNV-----------SKIKNLKLGYLT 72
Cdd:PRK11231 3 LRTENLTVGYGTKRILNDLSLSLPTGKITALIGPNGCGKSTLLKCFARLLTPQSGTVflgdkpismlsSRQLARRLALLP 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 73 QQMTLNSNATVFEEMSkpfehikrmeslikeetdwlskhandYDSDTYKTHMSRyesLSNQFEQLEGYQYEskiKTvlHG 152
Cdd:PRK11231 83 QHHLTPEGITVRELVA--------------------------YGRSPWLSLWGR---LSAEDNARVNQAME---QT--RI 128
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 153 LNFSEedfnKPINDFSGGQKTRLSLAQMLLNEPDLLLLDEPTNHLDLETTKWLEDYLRYFKGA---IVIISHD-----RY 224
Cdd:PRK11231 129 NHLAD----RRLTDLSGGQRQRAFLAMVLAQDTPVVLLDEPTTYLDINHQVELMRLMRELNTQgktVVTVLHDlnqasRY 204
|
|
| PRK10982 |
PRK10982 |
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional |
9-60 |
1.72e-04 |
|
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
Pssm-ID: 182880 [Multi-domain] Cd Length: 491 Bit Score: 44.72 E-value: 1.72e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 446524717 9 ISKSFDGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNV 60
Cdd:PRK10982 4 ISKSFPGVKALDNVNLKVRPHSIHALMGENGAGKSTLLKCLFGIYQKDSGSI 55
|
|
| ABC_Rad50 |
cd03240 |
ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ... |
158-229 |
1.87e-04 |
|
ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ATP-binding cassette of ABC transporters, but are not associated with membrane-spanning domains. The conserved ATP-binding motifs common to Rad50 and the ABC transporter family include the Walker A and Walker B motifs, the Q loop, a histidine residue in the switch region, a D-loop, and a conserved LSGG sequence. This conserved sequence, LSGG, is the most specific and characteristic motif of this family and is thus known as the ABC signature sequence.
Pssm-ID: 213207 [Multi-domain] Cd Length: 204 Bit Score: 42.98 E-value: 1.87e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 158 EDFNKPIND----FSGGQKT------RLSLAQMLLNEPDLLLLDEPTNHLDLET-TKWLEDYLRYFKGA----IVIISHD 222
Cdd:cd03240 103 GESNWPLLDmrgrCSGGEKVlasliiRLALAETFGSNCGILALDEPTTNLDEENiEESLAEIIEERKSQknfqLIVITHD 182
|
....*..
gi 446524717 223 RYFLDKI 229
Cdd:cd03240 183 EELVDAA 189
|
|
| cbiO |
PRK13652 |
cobalt transporter ATP-binding subunit; Provisional |
1-263 |
1.92e-04 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 172200 [Multi-domain] Cd Length: 277 Bit Score: 43.64 E-value: 1.92e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 1 MILLQLNHISKSFDGE-DIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNVskiknlklgyltqqmtlns 79
Cdd:PRK13652 1 MHLIETRDLCYSYSGSkEALNNINFIAPRNSRIAVIGPNGAGKSTLFRHFNGILKPTSGSV------------------- 61
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 80 natvfeemskpfehIKRMESLIKEETDWLSKHA----NDYDSDTYKTHMSRYESLSNQFEQLEGYQYESKIKTVLHGLNF 155
Cdd:PRK13652 62 --------------LIRGEPITKENIREVRKFVglvfQNPDDQIFSPTVEQDIAFGPINLGLDEETVAHRVSSALHMLGL 127
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 156 SEEDFNKPiNDFSGGQKTRLSLAQMLLNEPDLLLLDEPTNHLDLETTKWLEDYLRYFK---GAIVIIS-HDRYFLDKIVT 231
Cdd:PRK13652 128 EELRDRVP-HHLSGGEKKRVAIAGVIAMEPQVLVLDEPTAGLDPQGVKELIDFLNDLPetyGMTVIFStHQLDLVPEMAD 206
|
250 260 270
....*....|....*....|....*....|..
gi 446524717 232 QIYDVALGDVKRYvGNYEEFIQQRDLYYQKRM 263
Cdd:PRK13652 207 YIYVMDKGRIVAY-GTVEEIFLQPDLLARVHL 237
|
|
| PRK10619 |
PRK10619 |
histidine ABC transporter ATP-binding protein HisP; |
4-200 |
1.92e-04 |
|
histidine ABC transporter ATP-binding protein HisP;
Pssm-ID: 182592 [Multi-domain] Cd Length: 257 Bit Score: 43.42 E-value: 1.92e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 4 LQLNHISKSFDGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNVSkIKNlklgyltQQMTL----NS 79
Cdd:PRK10619 6 LNVIDLHKRYGEHEVLKGVSLQANAGDVISIIGSSGSGKSTFLRCINFLEKPSEGSIV-VNG-------QTINLvrdkDG 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 80 NATVFEemskpfehiKRMESLIKEETDWLSKHANDYdsdtykTHMSRYESLSNQFEQLEGY-QYESKIKTV--LHGLNFS 156
Cdd:PRK10619 78 QLKVAD---------KNQLRLLRTRLTMVFQHFNLW------SHMTVLENVMEAPIQVLGLsKQEARERAVkyLAKVGID 142
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 446524717 157 EEDFNKPINDFSGGQKTRLSLAQMLLNEPDLLLLDEPTNHLDLE 200
Cdd:PRK10619 143 ERAQGKYPVHLSGGQQQRVSIARALAMEPEVLLFDEPTSALDPE 186
|
|
| artP |
PRK11124 |
arginine transporter ATP-binding subunit; Provisional |
4-233 |
2.00e-04 |
|
arginine transporter ATP-binding subunit; Provisional
Pssm-ID: 182980 [Multi-domain] Cd Length: 242 Bit Score: 43.46 E-value: 2.00e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 4 LQLNHISKSFDGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNVS---------------KIKNL-- 66
Cdd:PRK11124 3 IQLNGINCFYGAHQALFDITLDCPQGETLVLLGPSGAGKSSLLRVLNLLEMPRSGTLNiagnhfdfsktpsdkAIRELrr 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 67 KLGYLTQQMTLNSNATVfeemskpfehikrMESLIKEETDWLSkhandydsdtykthMSRYESLSNQFEQLEGYQYESKI 146
Cdd:PRK11124 83 NVGMVFQQYNLWPHLTV-------------QQNLIEAPCRVLG--------------LSKDQALARAEKLLERLRLKPYA 135
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 147 KTV-LHglnfseedfnkpindFSGGQKTRLSLAQMLLNEPDLLLLDEPTNHLDLETTKWLEDYLRYFKG-AI--VIISHD 222
Cdd:PRK11124 136 DRFpLH---------------LSGGQQQRVAIARALMMEPQVLLFDEPTAALDPEITAQIVSIIRELAEtGItqVIVTHE 200
|
250
....*....|.
gi 446524717 223 RYFLDKIVTQI 233
Cdd:PRK11124 201 VEVARKTASRV 211
|
|
| COG4674 |
COG4674 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
3-231 |
2.01e-04 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 443710 [Multi-domain] Cd Length: 250 Bit Score: 43.57 E-value: 2.01e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 3 LLQLNHISKSFDGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNV------------SKIKNLKLGY 70
Cdd:COG4674 10 ILYVEDLTVSFDGFKALNDLSLYVDPGELRVIIGPNGAGKTTLMDVITGKTRPDSGSVlfggtdltgldeHEIARLGIGR 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 71 LTQqmtlnsNATVFEEMSkPFEHIKrmeslikeetdwLSkhandydsdtYKTHMSRYESLsnqFEQLEGYQyESKIKTVL 150
Cdd:COG4674 90 KFQ------KPTVFEELT-VFENLE------------LA----------LKGDRGVFASL---FARLTAEE-RDRIEEVL 136
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 151 H--GLnfsEEDFNKPINDFSGGQKTRLS----LAQ-----MllnepdlllLDEPTNHL-DLETTKwLEDYLRYFKG--AI 216
Cdd:COG4674 137 EtiGL---TDKADRLAGLLSHGQKQWLEigmlLAQdpkllL---------LDEPVAGMtDAETER-TAELLKSLAGkhSV 203
|
250
....*....|....*...
gi 446524717 217 VIISHDRYFLDKI---VT 231
Cdd:COG4674 204 VVVEHDMEFVRQIarkVT 221
|
|
| PRK15056 |
PRK15056 |
manganese/iron ABC transporter ATP-binding protein; |
14-210 |
2.06e-04 |
|
manganese/iron ABC transporter ATP-binding protein;
Pssm-ID: 185016 [Multi-domain] Cd Length: 272 Bit Score: 43.72 E-value: 2.06e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 14 DGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNVSKiknlkLGYLTQQmTLNSNATVFEEMSkpfeh 93
Cdd:PRK15056 18 NGHTALRDASFTVPGGSIAALVGVNGSGKSTLFKALMGFVRLASGKISI-----LGQPTRQ-ALQKNLVAYVPQS----- 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 94 ikrmeslikEETDW-LSKHANDYdsdtykTHMSRYESLSnqFEQLEGYQYESKIKTVLHGLNFSEEDfNKPINDFSGGQK 172
Cdd:PRK15056 87 ---------EEVDWsFPVLVEDV------VMMGRYGHMG--WLRRAKKRDRQIVTAALARVDMVEFR-HRQIGELSGGQK 148
|
170 180 190
....*....|....*....|....*....|....*...
gi 446524717 173 TRLSLAQMLLNEPDLLLLDEPTNHLDLETTKWLEDYLR 210
Cdd:PRK15056 149 KRVFLARAIAQQGQVILLDEPFTGVDVKTEARIISLLR 186
|
|
| PRK10261 |
PRK10261 |
glutathione transporter ATP-binding protein; Provisional |
328-513 |
2.11e-04 |
|
glutathione transporter ATP-binding protein; Provisional
Pssm-ID: 182342 [Multi-domain] Cd Length: 623 Bit Score: 44.46 E-value: 2.11e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 328 NDVMHVKNLEIGYQ-----TAITKPISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITFGANLQ-------IG 395
Cdd:PRK10261 10 RDVLAVENLNIAFMqeqqkIAAVRNLSFSLQRGETLAIVGESGSGKSVTALALMRLLEQAGGLVQCDKMLLrrrsrqvIE 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 396 YYDQKQAE------------FKSSKTILDYVW---DQYP--------LMNEKDIRAV-----LGRFLFVQDDVKKIINDL 447
Cdd:PRK10261 90 LSEQSAAQmrhvrgadmamiFQEPMTSLNPVFtvgEQIAesirlhqgASREEAMVEAkrmldQVRIPEAQTILSRYPHQL 169
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 448 SGGEKARLQLALLMLQRDNVLILDEPTNHLDIDSKEMLEQAL----QHFEGTILFVSHDRYFINQLANKV 513
Cdd:PRK10261 170 SGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIkvlqKEMSMGVIFITHDMGVVAEIADRV 239
|
|
| cbiO |
PRK13639 |
cobalt transporter ATP-binding subunit; Provisional |
3-222 |
2.43e-04 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184199 [Multi-domain] Cd Length: 275 Bit Score: 43.53 E-value: 2.43e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 3 LLQLNHISKSF-DGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNVsKIKNLKLGYLTQQMtLNSNA 81
Cdd:PRK13639 1 ILETRDLKYSYpDGTEALKGINFKAEKGEMVALLGPNGAGKSTLFLHFNGILKPTSGEV-LIKGEPIKYDKKSL-LEVRK 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 82 TVFEEMSKPFEHIkrmeslikeetdwlskHANDYDSDTYKTHMSRyeslsnqfeQLEGYQYESKIKTVLHGLnfSEEDF- 160
Cdd:PRK13639 79 TVGIVFQNPDDQL----------------FAPTVEEDVAFGPLNL---------GLSKEEVEKRVKEALKAV--GMEGFe 131
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446524717 161 NKPINDFSGGQKTRLSLAQMLLNEPDLLLLDEPTNHLD----LETTKWLEDYLRyfKGAIVIIS-HD 222
Cdd:PRK13639 132 NKPPHHLSGGQKKRVAIAGILAMKPEIIVLDEPTSGLDpmgaSQIMKLLYDLNK--EGITIIIStHD 196
|
|
| livF |
PRK11614 |
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF; |
348-474 |
2.75e-04 |
|
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;
Pssm-ID: 183231 [Multi-domain] Cd Length: 237 Bit Score: 42.94 E-value: 2.75e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 348 ISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITFGA---------------------------------NLQI 394
Cdd:PRK11614 24 VSLHINQGEIVTLIGANGAGKTTLLGTLCGDPRATSGRIVFDGkditdwqtakimreavaivpegrrvfsrmtveeNLAM 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 395 GYYDQKQAEFKSSktiLDYVWDQYPLMNEKDIRAVlgrflfvqddvkkiiNDLSGGEKARLQLALLMLQRDNVLILDEPT 474
Cdd:PRK11614 104 GGFFAERDQFQER---IKWVYELFPRLHERRIQRA---------------GTMSGGEQQMLAIGRALMSQPRLLLLDEPS 165
|
|
| tagH |
PRK13545 |
teichoic acids export protein ATP-binding subunit; Provisional |
21-60 |
2.94e-04 |
|
teichoic acids export protein ATP-binding subunit; Provisional
Pssm-ID: 184130 [Multi-domain] Cd Length: 549 Bit Score: 43.73 E-value: 2.94e-04
10 20 30 40
....*....|....*....|....*....|....*....|
gi 446524717 21 DVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNV 60
Cdd:PRK13545 42 NISFEVPEGEIVGIIGLNGSGKSTLSNLIAGVTMPNKGTV 81
|
|
| urea_trans_UrtE |
TIGR03410 |
urea ABC transporter, ATP-binding protein UrtE; Members of this protein family are ABC ... |
4-194 |
2.99e-04 |
|
urea ABC transporter, ATP-binding protein UrtE; Members of this protein family are ABC transporter ATP-binding subunits associated with urea transport and metabolism. This protein is found in a conserved five-gene transport operon typically found adjacent to urease genes. It was shown in Cyanobacteria that disruption leads to the loss of high-affinity urea transport activity. [Transport and binding proteins, Amino acids, peptides and amines]
Pssm-ID: 274567 [Multi-domain] Cd Length: 230 Bit Score: 42.90 E-value: 2.99e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 4 LQLNHISKSFDGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSG-------NVSKIK-----NLKLGYL 71
Cdd:TIGR03410 1 LEVSNLNVYYGQSHILRGVSLEVPKGEVTCVLGRNGVGKTTLLKTLMGLLPVKSGsirldgeDITKLPpheraRAGIAYV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 72 TQQMTLNSNATVFEEMSKPFEHIKRMESLIKEETdwlskhandydsdtykthmsryeslsnqfeqlegYQYESKIKTVLH 151
Cdd:TIGR03410 81 PQGREIFPRLTVEENLLTGLAALPRRSRKIPDEI----------------------------------YELFPVLKEMLG 126
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 446524717 152 glnfseedfnKPINDFSGGQKTRLSLAQMLLNEPDLLLLDEPT 194
Cdd:TIGR03410 127 ----------RRGGDLSGGQQQQLAIARALVTRPKLLLLDEPT 159
|
|
| MRP_assoc_pro |
TIGR00957 |
multi drug resistance-associated protein (MRP); This model describes multi drug ... |
18-259 |
3.00e-04 |
|
multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]
Pssm-ID: 188098 [Multi-domain] Cd Length: 1522 Bit Score: 44.17 E-value: 3.00e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 18 IFTDVDFEVKTGERIGIVGRNGAGKST----LMKIIAGVEN---YDSGNVSKIKnlkLGYLTQQMTLNSNATVFeemskp 90
Cdd:TIGR00957 1301 VLRHINVTIHGGEKVGIVGRTGAGKSSltlgLFRINESAEGeiiIDGLNIAKIG---LHDLRFKITIIPQDPVL------ 1371
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 91 FEHIKRME----SLIKEETDWLSkhandydsdtykthmsryeslsnqfeqLEGYQYESKIKTVLHGLNF--SEEDFNkpi 164
Cdd:TIGR00957 1372 FSGSLRMNldpfSQYSDEEVWWA---------------------------LELAHLKTFVSALPDKLDHecAEGGEN--- 1421
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 165 ndFSGGQKTRLSLAQMLLNEPDLLLLDEPTNHLDLETTKWLEDYLR-YFKGAIVI-ISHDryfLDKIV--TQIYDVALGD 240
Cdd:TIGR00957 1422 --LSVGQRQLVCLARALLRKTKILVLDEATAAVDLETDNLIQSTIRtQFEDCTVLtIAHR---LNTIMdyTRVIVLDKGE 1496
|
250
....*....|....*....
gi 446524717 241 VKRYvGNYEEFIQQRDLYY 259
Cdd:TIGR00957 1497 VAEF-GAPSNLLQQRGIFY 1514
|
|
| PRK11831 |
PRK11831 |
phospholipid ABC transporter ATP-binding protein MlaF; |
348-392 |
3.38e-04 |
|
phospholipid ABC transporter ATP-binding protein MlaF;
Pssm-ID: 236997 [Multi-domain] Cd Length: 269 Bit Score: 42.83 E-value: 3.38e-04
10 20 30 40
....*....|....*....|....*....|....*....|....*.
gi 446524717 348 ISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITF-GANL 392
Cdd:PRK11831 26 ISLTVPRGKITAIMGPSGIGKTTLLRLIGGQIAPDHGEILFdGENI 71
|
|
| ABC_MTABC3_MDL1_MDL2 |
cd03249 |
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 ... |
18-221 |
3.53e-04 |
|
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 (also known as ABCB6) is a mitochondrial ATP-binding cassette protein involved in iron homeostasis and one of four ABC transporters expressed in the mitochondrial inner membrane, the other three being MDL1(ABC7), MDL2, and ATM1. In fact, the yeast MDL1 (multidrug resistance-like protein 1) and MDL2 (multidrug resistance-like protein 2) transporters are also included in this CD. MDL1 is an ATP-dependent permease that acts as a high-copy suppressor of ATM1 and is thought to have a role in resistance to oxidative stress. Interestingly, subfamily B is more closely related to the carboxyl-terminal component of subfamily C than the two halves of ABCC molecules are with one another.
Pssm-ID: 213216 [Multi-domain] Cd Length: 238 Bit Score: 42.53 E-value: 3.53e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 18 IFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNV----SKIKNLKLGYLTQQMTLNS------NATVFE-- 85
Cdd:cd03249 18 ILKGLSLTIPPGKTVALVGSSGCGKSTVVSLLERFYDPTSGEIlldgVDIRDLNLRWLRSQIGLVSqepvlfDGTIAEni 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 86 EMSKPfehikrmeSLIKEETDWLSKHANDYDSdtykthmsrYESLSNQFEQLEGyQYESKIktvlhglnfseedfnkpin 165
Cdd:cd03249 98 RYGKP--------DATDEEVEEAAKKANIHDF---------IMSLPDGYDTLVG-ERGSQL------------------- 140
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 446524717 166 dfSGGQKTRLSLAQMLLNEPDLLLLDEPTNHLDLETTKWLEDYL-RYFKG-AIVIISH 221
Cdd:cd03249 141 --SGGQKQRIAIARALLRNPKILLLDEATSALDAESEKLVQEALdRAMKGrTTIVIAH 196
|
|
| PRK11831 |
PRK11831 |
phospholipid ABC transporter ATP-binding protein MlaF; |
18-102 |
3.73e-04 |
|
phospholipid ABC transporter ATP-binding protein MlaF;
Pssm-ID: 236997 [Multi-domain] Cd Length: 269 Bit Score: 42.83 E-value: 3.73e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 18 IFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNV----SKIKNL----------KLGYLTQQMTLNSNATV 83
Cdd:PRK11831 22 IFDNISLTVPRGKITAIMGPSGIGKTTLLRLIGGQIAPDHGEIlfdgENIPAMsrsrlytvrkRMSMLFQSGALFTDMNV 101
|
90 100
....*....|....*....|
gi 446524717 84 FEEMSKPF-EHIKRMESLIK 102
Cdd:PRK11831 102 FDNVAYPLrEHTQLPAPLLH 121
|
|
| YejF |
COG4172 |
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ... |
21-45 |
4.34e-04 |
|
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 443332 [Multi-domain] Cd Length: 533 Bit Score: 43.13 E-value: 4.34e-04
10 20
....*....|....*....|....*
gi 446524717 21 DVDFEVKTGERIGIVGRNGAGKSTL 45
Cdd:COG4172 304 GVSLTLRRGETLGLVGESGSGKSTL 328
|
|
| AAA |
smart00382 |
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ... |
28-101 |
4.51e-04 |
|
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.
Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 41.20 E-value: 4.51e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446524717 28 TGERIGIVGRNGAGKSTLMKIIAGVENYDSGNVSKIknlKLGYLTQQMTLNSNATVFEEMSKPFEHIKRMESLI 101
Cdd:smart00382 1 PGEVILIVGPPGSGKTTLARALARELGPPGGGVIYI---DGEDILEEVLDQLLLIIVGGKKASGSGELRLRLAL 71
|
|
| YejF |
COG4172 |
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ... |
1-43 |
4.98e-04 |
|
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 443332 [Multi-domain] Cd Length: 533 Bit Score: 43.13 E-value: 4.98e-04
10 20 30 40
....*....|....*....|....*....|....*....|....*..
gi 446524717 1 MILLQLNHISKSFDGEDIFT----DVDFEVKTGERIGIVGRNGAGKS 43
Cdd:COG4172 4 MPLLSVEDLSVAFGQGGGTVeavkGVSFDIAAGETLALVGESGSGKS 50
|
|
| YnjD |
COG4136 |
ABC-type uncharacterized transport system YnjBCD, ATPase component [General function ... |
4-222 |
4.99e-04 |
|
ABC-type uncharacterized transport system YnjBCD, ATPase component [General function prediction only];
Pssm-ID: 443311 [Multi-domain] Cd Length: 211 Bit Score: 41.70 E-value: 4.99e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 4 LQLNHISKSFDGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYD---SGNV----SKIKNL-----KLGYL 71
Cdd:COG4136 2 LSLENLTITLGGRPLLAPLSLTVAPGEILTLMGPSGSGKSTLLAAIAGTLSPAfsaSGEVllngRRLTALpaeqrRIGIL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 72 TQQMTLNSNATVFEEMskPF---EHIKRMEslikeetdwlskhandydsdtykthmsRYESLSNQFEQLEgyqyeskikt 148
Cdd:COG4136 82 FQDDLLFPHLSVGENL--AFalpPTIGRAQ---------------------------RRARVEQALEEAG---------- 122
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446524717 149 vLHGLnfseedFNKPINDFSGGQKTRLSLAQMLLNEPDLLLLDEPTNHLDLETTKWLEDY----LRYFKGAIVIISHD 222
Cdd:COG4136 123 -LAGF------ADRDPATLSGGQRARVALLRALLAEPRALLLDEPFSKLDAALRAQFREFvfeqIRQRGIPALLVTHD 193
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
532-642 |
5.46e-04 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 43.39 E-value: 5.46e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 532 IEKVEEAEALKAHQEEQSVNVQAHEKSMEQSSYHNQKEQRREQRKLERQISECENEIETLETTILQIDEQLTQPEvynnp 611
Cdd:COG1196 283 LEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAE----- 357
|
90 100 110
....*....|....*....|....*....|.
gi 446524717 612 QKANELAIQKQDSEQKLEHAMSKWEELQQKL 642
Cdd:COG1196 358 AELAEAEEALLEAEAELAEAEEELEELAEEL 388
|
|
| ECF_ATPase_2 |
TIGR04521 |
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette ... |
21-222 |
5.76e-04 |
|
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the downstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 275314 [Multi-domain] Cd Length: 277 Bit Score: 42.05 E-value: 5.76e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 21 DVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNV---------SKIKNL-----KLGYLTQqmtlNSNATVFEE 86
Cdd:TIGR04521 23 DVSLTIEDGEFVAIIGHTGSGKSTLIQHLNGLLKPTSGTVtidgrditaKKKKKLkdlrkKVGLVFQ----FPEHQLFEE 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 87 MSkpFEHI----KRMeSLIKEETdwlskhandydsdtykthmsryeslsnqfeqlegyqyESKIKTVLHGLNFSEEDFNK 162
Cdd:TIGR04521 99 TV--YKDIafgpKNL-GLSEEEA-------------------------------------EERVKEALELVGLDEEYLER 138
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446524717 163 PINDFSGGQKTRLSLAQMLLNEPDLLLLDEPTNHLDLETTKWLEDYLRYF----KGAIVIISHD 222
Cdd:TIGR04521 139 SPFELSGGQMRRVAIAGVLAMEPEVLILDEPTAGLDPKGRKEILDLFKRLhkekGLTVILVTHS 202
|
|
| COG3950 |
COG3950 |
Predicted ATP-binding protein involved in virulence [General function prediction only]; |
19-178 |
7.13e-04 |
|
Predicted ATP-binding protein involved in virulence [General function prediction only];
Pssm-ID: 443150 [Multi-domain] Cd Length: 276 Bit Score: 41.91 E-value: 7.13e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 19 FTDVDFEVKTGERIG-IVGRNGAGKSTLMKIIAGVENYDSGNVSKIKNLKL---------------GYLTQQMTLNSNAT 82
Cdd:COG3950 14 FEDLEIDFDNPPRLTvLVGENGSGKTTLLEAIALALSGLLSRLDDVKFRKLlirngefgdsaklilYYGTSRLLLDGPLK 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 83 VFEE-MSKPFEHIKRMESLIKEETD------WLSKHANDYDSDTYKTHMSRYESLSNQFEQLEGYQYESKIKTVLHGLNF 155
Cdd:COG3950 94 KLERlKEEYFSRLDGYDSLLDEDSNlrefleWLREYLEDLENKLSDELDEKLEAVREALNKLLPDFKDIRIDRDPGRLVI 173
|
170 180
....*....|....*....|....
gi 446524717 156 SEEDFNK-PINDFSGGQKTRLSLA 178
Cdd:COG3950 174 LDKNGEElPLNQLSDGERSLLALV 197
|
|
| SbcC |
COG0419 |
DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]; |
358-502 |
7.17e-04 |
|
DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair];
Pssm-ID: 440188 [Multi-domain] Cd Length: 204 Bit Score: 41.15 E-value: 7.17e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 358 IAIIGPNGIGKSTLIKTIA--------NQQKALNGYITFGAN-------------------------------------- 391
Cdd:COG0419 26 NLIVGPNGAGKSTILEAIRyalygkarSRSKLRSDLINVGSEeasvelefehggkryrierrqgefaefleakpserkea 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 392 ----LQIGYYDQKQAEFKSSKTILDYVWDQypLMNEKDIRAVLGRFLFVQDDVKkiinDLSGGEKARLQLALLMlqrdnV 467
Cdd:COG0419 106 lkrlLGLEIYEELKERLKELEEALESALEE--LAELQKLKQEILAQLSGLDPIE----TLSGGERLRLALADLL-----S 174
|
170 180 190
....*....|....*....|....*....|....*
gi 446524717 468 LILDepTNHLDIDSKEMLEQALQhfegTILFVSHD 502
Cdd:COG0419 175 LILD--FGSLDEERLERLLDALE----ELAIITHV 203
|
|
| PRK15112 |
PRK15112 |
peptide ABC transporter ATP-binding protein SapF; |
346-494 |
7.23e-04 |
|
peptide ABC transporter ATP-binding protein SapF;
Pssm-ID: 185067 [Multi-domain] Cd Length: 267 Bit Score: 41.70 E-value: 7.23e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 346 KPISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYITF-GANLQIGYYDQKQAE----FKSSKT----------I 410
Cdd:PRK15112 30 KPLSFTLREGQTLAIIGENGSGKSTLAKMLAGMIEPTSGELLIdDHPLHFGDYSYRSQRirmiFQDPSTslnprqrisqI 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 411 LDYVW----DQYPLMNEKDIRAVLGRFLFVQDDVKKIINDLSGGEKARLQLALLMLQRDNVLILDEPTNHLDIDSKE--- 483
Cdd:PRK15112 110 LDFPLrlntDLEPEQREKQIIETLRQVGLLPDHASYYPHMLAPGQKQRLGLARALILRPKVIIADEALASLDMSMRSqli 189
|
170
....*....|...
gi 446524717 484 --MLEqaLQHFEG 494
Cdd:PRK15112 190 nlMLE--LQEKQG 200
|
|
| ABC_UvrA |
cd03238 |
ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in ... |
348-522 |
7.82e-04 |
|
ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins, and UvrB having one ATP binding site that is structurally related to that of helicases.
Pssm-ID: 213205 [Multi-domain] Cd Length: 176 Bit Score: 40.77 E-value: 7.82e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 348 ISIEVSKGDHIAIIGPNGIGKSTLIKTI--ANQQKALNGYI-TFGANLQIgYYDQKQAefkSSKTILDYVwdqyplmnek 424
Cdd:cd03238 14 LDVSIPLNVLVVVTGVSGSGKSTLVNEGlyASGKARLISFLpKFSRNKLI-FIDQLQF---LIDVGLGYL---------- 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 425 diraVLGRflfvqddvkkIINDLSGGEKARLQLALLMLQR--DNVLILDEPTNHLDIDSKEMLeqaLQHFEG------TI 496
Cdd:cd03238 80 ----TLGQ----------KLSTLSGGELQRVKLASELFSEppGTLFILDEPSTGLHQQDINQL---LEVIKGlidlgnTV 142
|
170 180
....*....|....*....|....*.
gi 446524717 497 LFVSHDRYFInQLANKVFDLTIDGGK 522
Cdd:cd03238 143 ILIEHNLDVL-SSADWIIDFGPGSGK 167
|
|
| thiQ |
TIGR01277 |
thiamine ABC transporter, ATP-binding protein; This model describes the energy-transducing ... |
23-242 |
8.93e-04 |
|
thiamine ABC transporter, ATP-binding protein; This model describes the energy-transducing ATPase subunit ThiQ of the ThiBPQ thiamine (and thiamine pyrophosphate) ABC transporter in several Proteobacteria. This protein is found so far only in Proteobacteria, and is found in complete genomes only if the ThiB and ThiP subunits are also found. [Transport and binding proteins, Other]
Pssm-ID: 130344 [Multi-domain] Cd Length: 213 Bit Score: 41.00 E-value: 8.93e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 23 DFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGnvskiknlklgyltqQMTLNS-NATVFEEMSKPFehikrmeSLI 101
Cdd:TIGR01277 18 DLNVADGEIVAIMGPSGAGKSTLLNLIAGFIEPASG---------------SIKVNDqSHTGLAPYQRPV-------SML 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 102 KEETDWLSkhandydsdtyktHMSRYESLS---NQFEQLEGYQYEsKIKTVLHGLNFSEEDFNKPiNDFSGGQKTRLSLA 178
Cdd:TIGR01277 76 FQENNLFA-------------HLTVRQNIGlglHPGLKLNAEQQE-KVVDAAQQVGIADYLDRLP-EQLSGGQRQRVALA 140
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446524717 179 QMLLNEPDLLLLDEPTNHLD----LETTKWLEDYLRYFKGAIVIISHDRYFLDKIVTQIYDVALGDVK 242
Cdd:TIGR01277 141 RCLVRPNPILLLDEPFSALDpllrEEMLALVKQLCSERQRTLLMVTHHLSDARAIASQIAVVSQGKIK 208
|
|
| cbiO |
PRK13643 |
energy-coupling factor transporter ATPase; |
21-221 |
9.15e-04 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184203 [Multi-domain] Cd Length: 288 Bit Score: 41.64 E-value: 9.15e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 21 DVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNVsKIKNLKLGYLTQQMTLNSnatVFEEMSKPFEHikrMESL 100
Cdd:PRK13643 24 DIDLEVKKGSYTALIGHTGSGKSTLLQHLNGLLQPTEGKV-TVGDIVVSSTSKQKEIKP---VRKKVGVVFQF---PESQ 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 101 IKEETdwlskHANDYDSDTYKTHMSRYESLSNQFEQLEGyqyeskiktvlhgLNFSEEDFNKPINDFSGGQKTRLSLAQM 180
Cdd:PRK13643 97 LFEET-----VLKDVAFGPQNFGIPKEKAEKIAAEKLEM-------------VGLADEFWEKSPFELSGGQMRRVAIAGI 158
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 446524717 181 LLNEPDLLLLDEPTNHLD----LETTKWLEDyLRYFKGAIVIISH 221
Cdd:PRK13643 159 LAMEPEVLVLDEPTAGLDpkarIEMMQLFES-IHQSGQTVVLVTH 202
|
|
| cbiO |
PRK13637 |
energy-coupling factor transporter ATPase; |
21-233 |
9.50e-04 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237455 [Multi-domain] Cd Length: 287 Bit Score: 41.57 E-value: 9.50e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 21 DVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNVS------KIKNLKLGYLTQQMTLnsnatVFEemskpFEHI 94
Cdd:PRK13637 25 NVNIEIEDGEFVGLIGHTGSGKSTLIQHLNGLLKPTSGKIIidgvdiTDKKVKLSDIRKKVGL-----VFQ-----YPEY 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 95 KRMESLIKEETDWLSKHANDYDSDTYKthmsryeslsnqfeqlegyqyesKIKTVLHGLNFSEEDF-NKPINDFSGGQKT 173
Cdd:PRK13637 95 QLFEETIEKDIAFGPINLGLSEEEIEN-----------------------RVKRAMNIVGLDYEDYkDKSPFELSGGQKR 151
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446524717 174 RLSLAQMLLNEPDLLLLDEPTNHLD-------LETTKWLEDylrYFKGAIVIISHDRYFLDKIVTQI 233
Cdd:PRK13637 152 RVAIAGVVAMEPKILILDEPTAGLDpkgrdeiLNKIKELHK---EYNMTIILVSHSMEDVAKLADRI 215
|
|
| fbpC |
PRK11432 |
ferric ABC transporter ATP-binding protein; |
325-503 |
9.92e-04 |
|
ferric ABC transporter ATP-binding protein;
Pssm-ID: 183133 [Multi-domain] Cd Length: 351 Bit Score: 41.63 E-value: 9.92e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 325 NTGNDVMHVKNL--EIGYQTAITKpISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYItfganlqigYYDQKQA 402
Cdd:PRK11432 1 MTQKNFVVLKNItkRFGSNTVIDN-LNLTIKQGTMVTLLGPSGCGKTTVLRLVAGLEKPTEGQI---------FIDGEDV 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 403 EfKSSKTILD--YVWDQYPLMNEKDIRAVLGRFLFVQ--------DDVK-------------KIINDLSGGEKARLQLAL 459
Cdd:PRK11432 71 T-HRSIQQRDicMVFQSYALFPHMSLGENVGYGLKMLgvpkeerkQRVKealelvdlagfedRYVDQISGGQQQRVALAR 149
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 446524717 460 LMLQRDNVLILDEPTNHLDID----SKEMLEQALQHFEGTILFVSHDR 503
Cdd:PRK11432 150 ALILKPKVLLFDEPLSNLDANlrrsMREKIRELQQQFNITSLYVTHDQ 197
|
|
| PRK10938 |
PRK10938 |
putative molybdenum transport ATP-binding protein ModF; Provisional |
346-501 |
1.09e-03 |
|
putative molybdenum transport ATP-binding protein ModF; Provisional
Pssm-ID: 182852 [Multi-domain] Cd Length: 490 Bit Score: 41.92 E-value: 1.09e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 346 KPI----SIEVSKGDHIAIIGPNGIGKSTLIKTIA--NQQKALNGYITFGANLQIG--YYDQKQ-AEFKSSKTILDY--- 413
Cdd:PRK10938 273 RPIlhnlSWQVNPGEHWQIVGPNGAGKSTLLSLITgdHPQGYSNDLTLFGRRRGSGetIWDIKKhIGYVSSSLHLDYrvs 352
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 414 ----------------VWDQYPLMNEKDIRAVLGRFLFVQDDVKKIINDLSGGEKARLQLALLMLQRDNVLILDEPTNHL 477
Cdd:PRK10938 353 tsvrnvilsgffdsigIYQAVSDRQQKLAQQWLDILGIDKRTADAPFHSLSWGQQRLALIVRALVKHPTLLILDEPLQGL 432
|
170 180
....*....|....*....|....*...
gi 446524717 478 DIDSKEM----LEQALQHFEGTILFVSH 501
Cdd:PRK10938 433 DPLNRQLvrrfVDVLISEGETQLLFVSH 460
|
|
| SbcC |
COG0419 |
DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]; |
11-222 |
1.21e-03 |
|
DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair];
Pssm-ID: 440188 [Multi-domain] Cd Length: 204 Bit Score: 40.76 E-value: 1.21e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 11 KSFDGEdifTDVDFEVKTgerIGIVGRNGAGKSTLMKIIA-GVENYDSGNVSKIKNLklgyltqqMTLNSNAT----VFE 85
Cdd:COG0419 11 RSYRDT---ETIDFDDGL---NLIVGPNGAGKSTILEAIRyALYGKARSRSKLRSDL--------INVGSEEAsvelEFE 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 86 EMSKPFEhIKRMESLIKEETDwlskhandYDSDTYK------THMSRYESLSNQFEQLEGyQYESKIKTVLHGLNFSEED 159
Cdd:COG0419 77 HGGKRYR-IERRQGEFAEFLE--------AKPSERKealkrlLGLEIYEELKERLKELEE-ALESALEELAELQKLKQEI 146
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446524717 160 FNK-----PINDFSGGQKTRLSLAQMLLNEPDlllldepTNHLDLETTKWLEDYLRyfkgAIVIISHD 222
Cdd:COG0419 147 LAQlsgldPIETLSGGERLRLALADLLSLILD-------FGSLDEERLERLLDALE----ELAIITHV 203
|
|
| PRK14247 |
PRK14247 |
phosphate ABC transporter ATP-binding protein; Provisional |
12-221 |
1.52e-03 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172735 [Multi-domain] Cd Length: 250 Bit Score: 40.67 E-value: 1.52e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 12 SFDGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKI------------IAGVENYDSGNVSKIKNLKLGYLTQqMTLN- 78
Cdd:PRK14247 12 SFGQVEVLDGVNLEIPDNTITALMGPSGSGKSTLLRVfnrlielypearVSGEVYLDGQDIFKMDVIELRRRVQ-MVFQi 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 79 ----SNATVFEEMSKPFehikRMESLIKeetdwlskhandydsdtykthmSRYESLSNQFEQLEGYQYESKIKTVLhgln 154
Cdd:PRK14247 91 pnpiPNLSIFENVALGL----KLNRLVK----------------------SKKELQERVRWALEKAQLWDEVKDRL---- 140
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446524717 155 fseedfNKPINDFSGGQKTRLSLAQMLLNEPDLLLLDEPTNHLDLETTKWLEDYLRYFKG--AIVIISH 221
Cdd:PRK14247 141 ------DAPAGKLSGGQQQRLCIARALAFQPEVLLADEPTANLDPENTAKIESLFLELKKdmTIVLVTH 203
|
|
| nikD |
PRK10418 |
nickel transporter ATP-binding protein NikD; Provisional |
425-513 |
1.53e-03 |
|
nickel transporter ATP-binding protein NikD; Provisional
Pssm-ID: 236688 [Multi-domain] Cd Length: 254 Bit Score: 40.84 E-value: 1.53e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 425 DIRAVLGRFLFvqddvkkiinDLSGGEKARLQLALLMLQRDNVLILDEPTNHLDIDSK----EMLEQALQHFEGTILFVS 500
Cdd:PRK10418 129 NAARVLKLYPF----------EMSGGMLQRMMIALALLCEAPFIIADEPTTDLDVVAQarilDLLESIVQKRALGMLLVT 198
|
90
....*....|...
gi 446524717 501 HDRYFINQLANKV 513
Cdd:PRK10418 199 HDMGVVARLADDV 211
|
|
| oppD |
PRK09473 |
oligopeptide transporter ATP-binding component; Provisional |
446-502 |
1.60e-03 |
|
oligopeptide transporter ATP-binding component; Provisional
Pssm-ID: 181888 [Multi-domain] Cd Length: 330 Bit Score: 41.25 E-value: 1.60e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446524717 446 DLSGGEKARLQLALLMLQRDNVLILDEPTNHLDIDSK----EMLEQALQHFEGTILFVSHD 502
Cdd:PRK09473 161 EFSGGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQaqimTLLNELKREFNTAIIMITHD 221
|
|
| PTZ00265 |
PTZ00265 |
multidrug resistance protein (mdr1); Provisional |
447-501 |
1.64e-03 |
|
multidrug resistance protein (mdr1); Provisional
Pssm-ID: 240339 [Multi-domain] Cd Length: 1466 Bit Score: 41.94 E-value: 1.64e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 446524717 447 LSGGEKARLQLALLMLQRDNVLILDEPTNHLDIDSKEMLEQAL----QHFEGTILFVSH 501
Cdd:PTZ00265 1359 LSGGQKQRIAIARALLREPKILLLDEATSSLDSNSEKLIEKTIvdikDKADKTIITIAH 1417
|
|
| PRK10790 |
PRK10790 |
SmdB family multidrug efflux ABC transporter permease/ATP-binding protein; |
333-490 |
1.68e-03 |
|
SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;
Pssm-ID: 182733 [Multi-domain] Cd Length: 592 Bit Score: 41.63 E-value: 1.68e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 333 VKNLEIGYQT--AITKPISIEVSKGDHIAIIGPNGIGKSTLiktianqqkalngyitfgANLQIGYYDQKQAEF----KS 406
Cdd:PRK10790 343 IDNVSFAYRDdnLVLQNINLSVPSRGFVALVGHTGSGKSTL------------------ASLLMGYYPLTEGEIrldgRP 404
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 407 SKTILDYVWDQYPLMNEKD---------IRAVLGRFL----------FVQ---------DDVKKII----NDLSGGEKAR 454
Cdd:PRK10790 405 LSSLSHSVLRQGVAMVQQDpvvladtflANVTLGRDIseeqvwqaleTVQlaelarslpDGLYTPLgeqgNNLSVGQKQL 484
|
170 180 190
....*....|....*....|....*....|....*.
gi 446524717 455 LQLALLMLQRDNVLILDEPTNHLDIDSKEMLEQALQ 490
Cdd:PRK10790 485 LALARVLVQTPQILILDEATANIDSGTEQAIQQALA 520
|
|
| PTZ00265 |
PTZ00265 |
multidrug resistance protein (mdr1); Provisional |
447-517 |
1.80e-03 |
|
multidrug resistance protein (mdr1); Provisional
Pssm-ID: 240339 [Multi-domain] Cd Length: 1466 Bit Score: 41.55 E-value: 1.80e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446524717 447 LSGGEKARLQLALLMLQRDNVLILDEPTNHLDIDSKEMLEQALQHFEGT---ILFVSHDRYFINQLANKVFDLT 517
Cdd:PTZ00265 580 LSGGQKQRISIARAIIRNPKILILDEATSSLDNKSEYLVQKTINNLKGNenrITIIIAHRLSTIRYANTIFVLS 653
|
|
| PRK11174 |
PRK11174 |
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed |
22-51 |
1.82e-03 |
|
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
Pssm-ID: 236870 [Multi-domain] Cd Length: 588 Bit Score: 41.37 E-value: 1.82e-03
10 20 30
....*....|....*....|....*....|
gi 446524717 22 VDFEVKTGERIGIVGRNGAGKSTLMKIIAG 51
Cdd:PRK11174 369 LNFTLPAGQRIALVGPSGAGKTSLLNALLG 398
|
|
| cbiO |
PRK13636 |
cobalt transporter ATP-binding subunit; Provisional |
3-222 |
2.07e-03 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184196 [Multi-domain] Cd Length: 283 Bit Score: 40.60 E-value: 2.07e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 3 LLQLNHISKSF-DGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNVSKiKNLKLGYLTQQ-MTLNSN 80
Cdd:PRK13636 5 ILKVEELNYNYsDGTHALKGININIKKGEVTAILGGNGAGKSTLFQNLNGILKPSSGRILF-DGKPIDYSRKGlMKLRES 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 81 -ATVFEemskpfehikrmeslikeetdwlskhandyDSDTYKTHMSRYESLSNQFEQLEGYQYESKiKTVLHGLNFS--E 157
Cdd:PRK13636 84 vGMVFQ------------------------------DPDNQLFSASVYQDVSFGAVNLKLPEDEVR-KRVDNALKRTgiE 132
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446524717 158 EDFNKPINDFSGGQKTRLSLAQMLLNEPDLLLLDEPTNHLD----LETTKWLEDYLRYFKGAIVIISHD 222
Cdd:PRK13636 133 HLKDKPTHCLSFGQKKRVAIAGVLVMEPKVLVLDEPTAGLDpmgvSEIMKLLVEMQKELGLTIIIATHD 201
|
|
| ABC2_perm_RbbA |
NF033858 |
ribosome-associated ATPase/putative transporter RbbA; |
21-52 |
2.16e-03 |
|
ribosome-associated ATPase/putative transporter RbbA;
Pssm-ID: 468210 [Multi-domain] Cd Length: 907 Bit Score: 41.26 E-value: 2.16e-03
10 20 30
....*....|....*....|....*....|..
gi 446524717 21 DVDFEVKTGERIGIVGRNGAGKSTLMKIIAGV 52
Cdd:NF033858 19 DVSLDIPAGCMVGLIGPDGVGKSSLLSLIAGA 50
|
|
| ABC_Pro_Gly_Betaine |
cd03294 |
ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This ... |
21-222 |
2.65e-03 |
|
ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This family comprises the glycine betaine/L-proline ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporters is the obligatory coupling of ATP hydrolysis to substrate translocation. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213261 [Multi-domain] Cd Length: 269 Bit Score: 39.93 E-value: 2.65e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 21 DVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNV---------------SKIKNLKLGYLTQQMTLNSNATVFE 85
Cdd:cd03294 42 DVSLDVREGEIFVIMGLSGSGKSTLLRCINRLIEPTSGKVlidgqdiaamsrkelRELRRKKISMVFQSFALLPHRTVLE 121
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 86 EMSKPFEhikrmeslIKeetdwlskhandydsdtyktHMSRYESLSNQFEQLEgyqyeskiktvLHGLnfsEEDFNKPIN 165
Cdd:cd03294 122 NVAFGLE--------VQ--------------------GVPRAEREERAAEALE-----------LVGL---EGWEHKYPD 159
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446524717 166 DFSGGQKTRLSLAQMLLNEPDLLLLDEPTNHLDLETTKWLEDYL----RYFKGAIVIISHD 222
Cdd:cd03294 160 ELSGGMQQRVGLARALAVDPDILLMDEAFSALDPLIRREMQDELlrlqAELQKTIVFITHD 220
|
|
| PRK15112 |
PRK15112 |
peptide ABC transporter ATP-binding protein SapF; |
3-70 |
2.66e-03 |
|
peptide ABC transporter ATP-binding protein SapF;
Pssm-ID: 185067 [Multi-domain] Cd Length: 267 Bit Score: 40.16 E-value: 2.66e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446524717 3 LLQLNHISKSFDGE---------DIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNVSkIKNLKLGY 70
Cdd:PRK15112 4 LLEVRNLSKTFRYRtgwfrrqtvEAVKPLSFTLREGQTLAIIGENGSGKSTLAKMLAGMIEPTSGELL-IDDHPLHF 79
|
|
| dppF |
PRK11308 |
dipeptide transporter ATP-binding subunit; Provisional |
448-526 |
3.14e-03 |
|
dipeptide transporter ATP-binding subunit; Provisional
Pssm-ID: 236898 [Multi-domain] Cd Length: 327 Bit Score: 40.33 E-value: 3.14e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 448 SGGEKARLQLA-LLMLQRDnVLILDEPTNHLDIDSKemlEQAL-------QHFEGTILFVSHDRYFINQLANKVFdltid 519
Cdd:PRK11308 156 SGGQRQRIAIArALMLDPD-VVVADEPVSALDVSVQ---AQVLnlmmdlqQELGLSYVFISHDLSVVEHIADEVM----- 226
|
....*..
gi 446524717 520 ggKMYLG 526
Cdd:PRK11308 227 --VMYLG 231
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
530-641 |
3.18e-03 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 40.53 E-value: 3.18e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 530 YYIEKVEEAEALKAHQEEQSVnVQAHEKSMEQSS----YHNQKEQRREQRKLERQISECENEIETLETTILQIDEQLTQP 605
Cdd:PRK12704 23 FVRKKIAEAKIKEAEEEAKRI-LEEAKKEAEAIKkealLEAKEEIHKLRNEFEKELRERRNELQKLEKRLLQKEENLDRK 101
|
90 100 110
....*....|....*....|....*....|....*.
gi 446524717 606 EVYNNpQKANELAIQKQDSEQKLEHAMSKWEELQQK 641
Cdd:PRK12704 102 LELLE-KREEELEKKEKELEQKQQELEKKEEELEEL 136
|
|
| PRK15093 |
PRK15093 |
peptide ABC transporter ATP-binding protein SapD; |
446-513 |
3.32e-03 |
|
peptide ABC transporter ATP-binding protein SapD;
Pssm-ID: 185049 [Multi-domain] Cd Length: 330 Bit Score: 40.17 E-value: 3.32e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446524717 446 DLSGGEKARLQLALLMLQRDNVLILDEPTNHLDIDSK----EMLEQALQHFEGTILFVSHDRYFINQLANKV 513
Cdd:PRK15093 158 ELTEGECQKVMIAIALANQPRLLIADEPTNAMEPTTQaqifRLLTRLNQNNNTTILLISHDLQMLSQWADKI 229
|
|
| ABC2_perm_RbbA |
NF033858 |
ribosome-associated ATPase/putative transporter RbbA; |
19-51 |
3.37e-03 |
|
ribosome-associated ATPase/putative transporter RbbA;
Pssm-ID: 468210 [Multi-domain] Cd Length: 907 Bit Score: 40.49 E-value: 3.37e-03
10 20 30
....*....|....*....|....*....|....*.
gi 446524717 19 FT---DVDFEVKTGERIGIVGRNGAGKSTLMKIIAG 51
Cdd:NF033858 279 FTavdHVSFRIRRGEIFGFLGSNGCGKSTTMKMLTG 314
|
|
| ABC2_perm_RbbA |
NF033858 |
ribosome-associated ATPase/putative transporter RbbA; |
426-474 |
3.90e-03 |
|
ribosome-associated ATPase/putative transporter RbbA;
Pssm-ID: 468210 [Multi-domain] Cd Length: 907 Bit Score: 40.49 E-value: 3.90e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 446524717 426 IRAVLGRFlfvqdDVKKIINDLSG----GEKARLQLALLMLQRDNVLILDEPT 474
Cdd:NF033858 378 VAEMLERF-----DLADVADALPDslplGIRQRLSLAVAVIHKPELLILDEPT 425
|
|
| PRK00635 |
PRK00635 |
excinuclease ABC subunit A; Provisional |
447-528 |
4.48e-03 |
|
excinuclease ABC subunit A; Provisional
Pssm-ID: 234806 [Multi-domain] Cd Length: 1809 Bit Score: 40.20 E-value: 4.48e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 447 LSGGEKARLQLALLML---QRDNVLILDEPTNHLDI-DSKEMLE--QALQHFEGTILFVSHDRYFInQLANKVFDLTIDG 520
Cdd:PRK00635 810 LSGGEIQRLKLAYELLapsKKPTLYVLDEPTTGLHThDIKALIYvlQSLTHQGHTVVIIEHNMHVV-KVADYVLELGPEG 888
|
....*...
gi 446524717 521 GKmyLGDY 528
Cdd:PRK00635 889 GN--LGGY 894
|
|
| PRK13546 |
PRK13546 |
teichoic acids export ABC transporter ATP-binding subunit TagH; |
7-62 |
4.56e-03 |
|
teichoic acids export ABC transporter ATP-binding subunit TagH;
Pssm-ID: 184131 [Multi-domain] Cd Length: 264 Bit Score: 39.41 E-value: 4.56e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 446524717 7 NHISKSFDGEDiftDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNVSK 62
Cdd:PRK13546 31 KHKNKTFFALD---DISLKAYEGDVIGLVGINGSGKSTLSNIIGGSLSPTVGKVDR 83
|
|
| PTZ00243 |
PTZ00243 |
ABC transporter; Provisional |
22-49 |
4.57e-03 |
|
ABC transporter; Provisional
Pssm-ID: 240327 [Multi-domain] Cd Length: 1560 Bit Score: 40.15 E-value: 4.57e-03
10 20 30
....*....|....*....|....*....|..
gi 446524717 22 VDFEVKTGERIGIVGRNGAGKSTL----MKII 49
Cdd:PTZ00243 1329 VSFRIAPREKVGIVGRTGSGKSTLlltfMRMV 1360
|
|
| PRK09700 |
PRK09700 |
D-allose ABC transporter ATP-binding protein AlsA; |
346-529 |
5.14e-03 |
|
D-allose ABC transporter ATP-binding protein AlsA;
Pssm-ID: 182036 [Multi-domain] Cd Length: 510 Bit Score: 39.77 E-value: 5.14e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 346 KPISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGYIT------------FGANLQIGYYDQK---------QAEF 404
Cdd:PRK09700 22 KSVNLTVYPGEIHALLGENGAGKSTLMKVLSGIHEPTKGTITinninynkldhkLAAQLGIGIIYQElsvideltvLENL 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 405 KSSKTILDYVWDqYPLMNEKDIR---AVLGRFLFVQDDVKKIINDLSGGEKARLQLALLMLQRDNVLILDEPTNHL---D 478
Cdd:PRK09700 102 YIGRHLTKKVCG-VNIIDWREMRvraAMMLLRVGLKVDLDEKVANLSISHKQMLEIAKTLMLDAKVIIMDEPTSSLtnkE 180
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 446524717 479 IDSKEMLEQALQHfEGT-ILFVSHDRYFINQLANKVFDLTiDGGKMYLGDYQ 529
Cdd:PRK09700 181 VDYLFLIMNQLRK-EGTaIVYISHKLAEIRRICDRYTVMK-DGSSVCSGMVS 230
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
531-642 |
5.74e-03 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 40.04 E-value: 5.74e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 531 YIEKVEEAEALKAHQEEQS--VNVQAHEKSMEQSSY-HNQKEQRREQRKLERQISECENEIETLETTILQIDEQLTQpev 607
Cdd:TIGR02168 251 AEEELEELTAELQELEEKLeeLRLEVSELEEEIEELqKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEE--- 327
|
90 100 110
....*....|....*....|....*....|....*
gi 446524717 608 ynNPQKANELAIQKQDSEQKLEHAMSKWEELQQKL 642
Cdd:TIGR02168 328 --LESKLDELAEELAELEEKLEELKEELESLEAEL 360
|
|
| YbjD |
COG3593 |
Predicted ATP-dependent endonuclease of the OLD family, contains P-loop ATPase and TOPRIM ... |
331-509 |
5.94e-03 |
|
Predicted ATP-dependent endonuclease of the OLD family, contains P-loop ATPase and TOPRIM domains [Replication, recombination and repair];
Pssm-ID: 442812 [Multi-domain] Cd Length: 359 Bit Score: 39.22 E-value: 5.94e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 331 MHVKNLEI----GYqtaitKPISIEVSKgDHIAIIGPNGIGKSTLIKTIanqQKALNGY--------------------- 385
Cdd:COG3593 1 MKLEKIKIknfrSI-----KDLSIELSD-DLTVLVGENNSGKSSILEAL---RLLLGPSssrkfdeedfylgddpdlpei 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 386 ---ITFGANLQ---------------IGYYDQKQAEFKSS----KTILDYVWDQYPLMNEKDIRAVLGRF--------LF 435
Cdd:COG3593 72 eieLTFGSLLSrllrlllkeedkeelEEALEELNEELKEAlkalNELLSEYLKELLDGLDLELELSLDELedllkslsLR 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 436 VQDDVKKIINDLSGGEKARLQLALLML-------QRDNVLILDEPTNHLDIDSKEMLEQALQHFEGT---ILFVSHDRYF 505
Cdd:COG3593 152 IEDGKELPLDRLGSGFQRLILLALLSAlaelkraPANPILLIEEPEAHLHPQAQRRLLKLLKELSEKpnqVIITTHSPHL 231
|
....
gi 446524717 506 INQL 509
Cdd:COG3593 232 LSEV 235
|
|
| ugpC |
PRK11650 |
sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC; |
342-376 |
6.10e-03 |
|
sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;
Pssm-ID: 236947 [Multi-domain] Cd Length: 356 Bit Score: 39.44 E-value: 6.10e-03
10 20 30
....*....|....*....|....*....|....*
gi 446524717 342 TAITKPISIEVSKGDHIAIIGPNGIGKSTLIKTIA 376
Cdd:PRK11650 17 TQVIKGIDLDVADGEFIVLVGPSGCGKSTLLRMVA 51
|
|
| PRK10790 |
PRK10790 |
SmdB family multidrug efflux ABC transporter permease/ATP-binding protein; |
4-271 |
6.13e-03 |
|
SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;
Pssm-ID: 182733 [Multi-domain] Cd Length: 592 Bit Score: 39.70 E-value: 6.13e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 4 LQLNHISKSF-DGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNVsKIKNLKLGYLTQQMTLNSNAT 82
Cdd:PRK10790 341 IDIDNVSFAYrDDNLVLQNINLSVPSRGFVALVGHTGSGKSTLASLLMGYYPLTEGEI-RLDGRPLSSLSHSVLRQGVAM 419
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 83 VFEE---MSKPFEHIKRMESLIKEETDWlskhandydsdtykthmsryeslsnqfEQLEGYQYESKIKTVLHGLN--FSE 157
Cdd:PRK10790 420 VQQDpvvLADTFLANVTLGRDISEEQVW---------------------------QALETVQLAELARSLPDGLYtpLGE 472
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 158 EDfnkpiNDFSGGQKTRLSLAQMLLNEPDLLLLDEPTNHLDLETTKWLEDYLRYF--KGAIVIISHDryfLDKIVT--QI 233
Cdd:PRK10790 473 QG-----NNLSVGQKQLLALARVLVQTPQILILDEATANIDSGTEQAIQQALAAVreHTTLVVIAHR---LSTIVEadTI 544
|
250 260 270
....*....|....*....|....*....|....*....
gi 446524717 234 YDVALGD-VKRyvGNYEEFIQQRDLYYQkrMqeYESQQA 271
Cdd:PRK10790 545 LVLHRGQaVEQ--GTHQQLLAAQGRYWQ--M--YQLQLA 577
|
|
| ArpD |
COG4618 |
ABC-type protease/lipase transport system, ATPase and permease components [Intracellular ... |
18-229 |
6.33e-03 |
|
ABC-type protease/lipase transport system, ATPase and permease components [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 443660 [Multi-domain] Cd Length: 563 Bit Score: 39.73 E-value: 6.33e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 18 IFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNV----SKIKNLK-------LGYLTQQMTLnSNATVFEe 86
Cdd:COG4618 347 ILRGVSFSLEPGEVLGVIGPSGSGKSTLARLLVGVWPPTAGSVrldgADLSQWDreelgrhIGYLPQDVEL-FDGTIAE- 424
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 87 mskpfeHIKRMESLIKEET----------DWLSKHANDYDsdtykthmsryeslsnqfeqlegyqyeskikTVL----HG 152
Cdd:COG4618 425 ------NIARFGDADPEKVvaaaklagvhEMILRLPDGYD-------------------------------TRIgeggAR 467
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 153 LnfseedfnkpindfSGGQKTRLSLAQ----------MllnepdllllDEPTNHLDLETTKWLEDYLRYFK---GAIVII 219
Cdd:COG4618 468 L--------------SGGQRQRIGLARalygdprlvvL----------DEPNSNLDDEGEAALAAAIRALKargATVVVI 523
|
250
....*....|...
gi 446524717 220 SHDRYFL---DKI 229
Cdd:COG4618 524 THRPSLLaavDKL 536
|
|
| cbiO |
PRK13640 |
energy-coupling factor transporter ATPase; |
18-63 |
6.40e-03 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184200 [Multi-domain] Cd Length: 282 Bit Score: 39.01 E-value: 6.40e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*.
gi 446524717 18 IFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNVSKI 63
Cdd:PRK13640 22 ALNDISFSIPRGSWTALIGHNGSGKSTISKLINGLLLPDDNPNSKI 67
|
|
| 3a01203 |
TIGR00954 |
Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, ... |
15-79 |
6.47e-03 |
|
Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]
Pssm-ID: 273360 [Multi-domain] Cd Length: 659 Bit Score: 39.73 E-value: 6.47e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446524717 15 GEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNVSKIKNLKLGYLTQQ--MTLNS 79
Cdd:TIGR00954 464 GDVLIESLSFEVPSGNNLLICGPNGCGKSSLFRILGELWPVYGGRLTKPAKGKLFYVPQRpyMTLGT 530
|
|
| dppD |
PRK11022 |
dipeptide transporter ATP-binding subunit; Provisional |
1-55 |
6.67e-03 |
|
dipeptide transporter ATP-binding subunit; Provisional
Pssm-ID: 182906 [Multi-domain] Cd Length: 326 Bit Score: 38.95 E-value: 6.67e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 446524717 1 MILLQLNHISKSF-DGEDIFTDVD---FEVKTGERIGIVGRNGAGKSTLMKIIAGVENY 55
Cdd:PRK11022 1 MALLNVDKLSVHFgDESAPFRAVDrisYSVKQGEVVGIVGESGSGKSVSSLAIMGLIDY 59
|
|
| PRK15134 |
PRK15134 |
microcin C ABC transporter ATP-binding protein YejF; Provisional |
162-513 |
7.13e-03 |
|
microcin C ABC transporter ATP-binding protein YejF; Provisional
Pssm-ID: 237917 [Multi-domain] Cd Length: 529 Bit Score: 39.30 E-value: 7.13e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 162 KPINDF----SGGQKTRLSLAQMLLNEPDLLLLDEPTNHLDLETTKWLEDYLRYFKG----AIVIISHDRyfldKIVTQI 233
Cdd:PRK15134 148 KRLTDYphqlSGGERQRVMIAMALLTRPELLIADEPTTALDVSVQAQILQLLRELQQelnmGLLFITHNL----SIVRKL 223
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 234 YD-VALgdvkryvgnyeefiqqrdlyyqkrMQEYESqqaeikrletfVEKNITRASTSGMAKS-RRKIL--------EKM 303
Cdd:PRK15134 224 ADrVAV------------------------MQNGRC-----------VEQNRAATLFSAPTHPyTQKLLnsepsgdpVPL 268
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 304 ERIDKPMLDAKSANIQF----GFDRNTgndvmhvknleIGYQTAItKPISIEVSKGDHIAIIGPNGIGKST----LIKTI 375
Cdd:PRK15134 269 PEPASPLLDVEQLQVAFpirkGILKRT-----------VDHNVVV-KNISFTLRPGETLGLVGESGSGKSTtglaLLRLI 336
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 376 ANQqkalnGYITF-GANLQ-------IGYYDQKQAEFKSSKTILDyvwdqyPLMNEKDIRA----VLGRFLFVQDDVKKI 443
Cdd:PRK15134 337 NSQ-----GEIWFdGQPLHnlnrrqlLPVRHRIQVVFQDPNSSLN------PRLNVLQIIEeglrVHQPTLSAAQREQQV 405
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 444 I-----------------NDLSGGEKARLQLALLMLQRDNVLILDEPTNHLDIDSK----EMLEQALQHFEGTILFVSHD 502
Cdd:PRK15134 406 IavmeevgldpetrhrypAEFSGGQRQRIAIARALILKPSLIILDEPTSSLDKTVQaqilALLKSLQQKHQLAYLFISHD 485
|
410
....*....|.
gi 446524717 503 RYFINQLANKV 513
Cdd:PRK15134 486 LHVVRALCHQV 496
|
|
| AAA_16 |
pfam13191 |
AAA ATPase domain; This family of domains contain a P-loop motif that is characteriztic of the ... |
357-499 |
7.60e-03 |
|
AAA ATPase domain; This family of domains contain a P-loop motif that is characteriztic of the AAA superfamily.
Pssm-ID: 433025 [Multi-domain] Cd Length: 167 Bit Score: 37.87 E-value: 7.60e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 357 HIAIIGPNGIGKSTLIKTIANQQKALNGYITFGANLQIGYYDQkQAEFKSSKTILDYVwdqyplmNEKDIRAVLGRFLFV 436
Cdd:pfam13191 26 SVLLTGEAGTGKTTLLRELLRALERDGGYFLRGKCDENLPYSP-LLEALTREGLLRQL-------LDELESSLLEAWRAA 97
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 437 QDDVKKIINDLSGGEKARLQLALL----MLQRDN---VLILDEpTNHLDIDSKEMLEQALQHFEGTILFV 499
Cdd:pfam13191 98 LLEALAPVPELPGDLAERLLDLLLrlldLLARGErplVLVLDD-LQWADEASLQLLAALLRLLESLPLLV 166
|
|
| PRK10575 |
PRK10575 |
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC; |
5-85 |
7.83e-03 |
|
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;
Pssm-ID: 182561 [Multi-domain] Cd Length: 265 Bit Score: 38.62 E-value: 7.83e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 5 QLNHISKSFDGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNV-----------SKIKNLKLGYLTQ 73
Cdd:PRK10575 13 ALRNVSFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEIlldaqpleswsSKAFARKVAYLPQ 92
|
90
....*....|..
gi 446524717 74 QMTLNSNATVFE 85
Cdd:PRK10575 93 QLPAAEGMTVRE 104
|
|
| PRK15134 |
PRK15134 |
microcin C ABC transporter ATP-binding protein YejF; Provisional |
21-222 |
8.12e-03 |
|
microcin C ABC transporter ATP-binding protein YejF; Provisional
Pssm-ID: 237917 [Multi-domain] Cd Length: 529 Bit Score: 39.30 E-value: 8.12e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 21 DVDFEVKTGERIGIVGRNGAGKST----LMKIIAGvenydSGNVSkIKNLKLGYLTQQMTLnsnatvfeemskPFEHikR 96
Cdd:PRK15134 304 NISFTLRPGETLGLVGESGSGKSTtglaLLRLINS-----QGEIW-FDGQPLHNLNRRQLL------------PVRH--R 363
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 97 MESLIKEETDWLSKHANdydsdtykTHMSRYESLSNQFEQLEGYQYESKIKTVLHGLNFSEEDFNKPINDFSGGQKTRLS 176
Cdd:PRK15134 364 IQVVFQDPNSSLNPRLN--------VLQIIEEGLRVHQPTLSAAQREQQVIAVMEEVGLDPETRHRYPAEFSGGQRQRIA 435
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 446524717 177 LAQMLLNEPDLLLLDEPTNHLD-------LETTKWLEDYLRYfkgAIVIISHD 222
Cdd:PRK15134 436 IARALILKPSLIILDEPTSSLDktvqaqiLALLKSLQQKHQL---AYLFISHD 485
|
|
| PRK14258 |
PRK14258 |
phosphate ABC transporter ATP-binding protein; Provisional |
4-229 |
8.70e-03 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 184593 [Multi-domain] Cd Length: 261 Bit Score: 38.48 E-value: 8.70e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 4 LQLNHISKSFDGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGnvSKIKNlKLGYLTQqmtlnsnaTV 83
Cdd:PRK14258 8 IKVNNLSFYYDTQKILEGVSMEIYQSKVTAIIGPSGCGKSTFLKCLNRMNELESE--VRVEG-RVEFFNQ--------NI 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 84 FEEMSKpFEHIKRMESLIKEETDWLSKHAndYDSDTYKTHMSRYE---SLSNQFEQ-LEGYQYESKIKTVLHglnfseed 159
Cdd:PRK14258 77 YERRVN-LNRLRRQVSMVHPKPNLFPMSV--YDNVAYGVKIVGWRpklEIDDIVESaLKDADLWDEIKHKIH-------- 145
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446524717 160 fnKPINDFSGGQKTRLSLAQMLLNEPDLLLLDEPTNHLDLETTKWLEDYLRYFK----GAIVIISHDRYFLDKI 229
Cdd:PRK14258 146 --KSALDLSGGQQQRLCIARALAVKPKVLLMDEPCFGLDPIASMKVESLIQSLRlrseLTMVIVSHNLHQVSRL 217
|
|
| araG |
PRK11288 |
L-arabinose ABC transporter ATP-binding protein AraG; |
20-60 |
8.92e-03 |
|
L-arabinose ABC transporter ATP-binding protein AraG;
Pssm-ID: 183077 [Multi-domain] Cd Length: 501 Bit Score: 39.12 E-value: 8.92e-03
10 20 30 40
....*....|....*....|....*....|....*....|.
gi 446524717 20 TDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSGNV 60
Cdd:PRK11288 270 EPISFSVRAGEIVGLFGLVGAGRSELMKLLYGATRRTAGQV 310
|
|
| ABCC_CFTR2 |
cd03289 |
ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator ... |
14-223 |
9.28e-03 |
|
ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.
Pssm-ID: 213256 [Multi-domain] Cd Length: 275 Bit Score: 38.30 E-value: 9.28e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 14 DGEDIFTDVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDsGNVskiknlklgyltQQMTLNSNATVFEEMSKPFEH 93
Cdd:cd03289 15 GGNAVLENISFSISPGQRVGLLGRTGSGKSTLLSAFLRLLNTE-GDI------------QIDGVSWNSVPLQKWRKAFGV 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 94 IKRMESLIkeetdwlskhandydSDTYKTHMSRYESLSNqfEQLEGYQYESKIKTVLH----GLNFSEEDFNKPIndfSG 169
Cdd:cd03289 82 IPQKVFIF---------------SGTFRKNLDPYGKWSD--EEIWKVAEEVGLKSVIEqfpgQLDFVLVDGGCVL---SH 141
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 446524717 170 GQKTRLSLAQMLLNEPDLLLLDEPTNHLDLETTKWLEDYLRY-FKGAIVIISHDR 223
Cdd:cd03289 142 GHKQLMCLARSVLSKAKILLLDEPSAHLDPITYQVIRKTLKQaFADCTVILSEHR 196
|
|
| cbiO |
PRK13645 |
energy-coupling factor transporter ATPase; |
21-222 |
9.63e-03 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184204 [Multi-domain] Cd Length: 289 Bit Score: 38.45 E-value: 9.63e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 21 DVDFEVKTGERIGIVGRNGAGKSTLMKIIAGVENYDSG-----------NVSKIKNLKlgYLTQQMTLnsnatVFEemsk 89
Cdd:PRK13645 29 NTSLTFKKNKVTCVIGTTGSGKSTMIQLTNGLIISETGqtivgdyaipaNLKKIKEVK--RLRKEIGL-----VFQ---- 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 90 pFEHIKRMESLIKEETDWLSKHANDYDSDTYKthmsryeslsnqfeqlegyqyesKIKTVLHGLNFSEEDFNKPINDFSG 169
Cdd:PRK13645 98 -FPEYQLFQETIEKDIAFGPVNLGENKQEAYK-----------------------KVPELLKLVQLPEDYVKRSPFELSG 153
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 446524717 170 GQKTRLSLAQMLLNEPDLLLLDEPTNHLDletTKWLEDYLRYF-------KGAIVIISHD 222
Cdd:PRK13645 154 GQKRRVALAGIIAMDGNTLVLDEPTGGLD---PKGEEDFINLFerlnkeyKKRIIMVTHN 210
|
|
| |
