|
Name |
Accession |
Description |
Interval |
E-value |
| FtsE |
COG2884 |
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning]; |
1-223 |
6.44e-138 |
|
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442130 [Multi-domain] Cd Length: 223 Bit Score: 385.56 E-value: 6.44e-138
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 1 MIKMTNVYKEYPNGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLAERDVPYFRRQ 80
Cdd:COG2884 1 MIRFENVSKRYPGGREALSDVSLEIEKGEFVFLTGPSGAGKSTLLKLLYGEERPTSGQVLVNGQDLSRLKRREIPYLRRR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 81 LGVIFQDFKLLPKLTVYENVSFALEVIEEEPDAIRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIVNRPKVVI 160
Cdd:COG2884 81 IGVVFQDFRLLPDRTVYENVALPLRVTGKSRKEIRRRVREVLDLVGLSDKAKALPHELSGGEQQRVAIARALVNRPELLL 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446516975 161 ADEPTGNLDIETALDIMNIFTRINERGTTIVMATHNADIVNTIRHRVIAIEGGKIVRDEIEGG 223
Cdd:COG2884 161 ADEPTGNLDPETSWEIMELLEEINRRGTTVLIATHDLELVDRMPKRVLELEDGRLVRDEARGV 223
|
|
| ABC_FtsE |
cd03292 |
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where ... |
2-215 |
3.46e-113 |
|
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages
Pssm-ID: 213259 [Multi-domain] Cd Length: 214 Bit Score: 322.82 E-value: 3.46e-113
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 2 IKMTNVYKEYPNGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLAERDVPYFRRQL 81
Cdd:cd03292 1 IEFINVTKTYPNGTAALDGINISISAGEFVFLVGPSGAGKSTLLKLIYKEELPTSGTIRVNGQDVSDLRGRAIPYLRRKI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 82 GVIFQDFKLLPKLTVYENVSFALEVIEEEPDAIRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIVNRPKVVIA 161
Cdd:cd03292 81 GVVFQDFRLLPDRNVYENVAFALEVTGVPPREIRKRVPAALELVGLSHKHRALPAELSGGEQQRVAIARAIVNSPTILIA 160
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 446516975 162 DEPTGNLDIETALDIMNIFTRINERGTTIVMATHNADIVNTIRHRVIAIEGGKI 215
Cdd:cd03292 161 DEPTGNLDPDTTWEIMNLLKKINKAGTTVVVATHAKELVDTTRHRVIALERGKL 214
|
|
| FtsE |
TIGR02673 |
cell division ATP-binding protein FtsE; This model describes FtsE, a member of the ABC ... |
1-214 |
4.63e-103 |
|
cell division ATP-binding protein FtsE; This model describes FtsE, a member of the ABC transporter ATP-binding protein family. This protein, and its permease partner FtsX, localize to the division site. In a number of species, the ftsEX gene pair is located next to FtsY, the signal recognition particle-docking protein. [Cellular processes, Cell division]
Pssm-ID: 131721 [Multi-domain] Cd Length: 214 Bit Score: 296.85 E-value: 4.63e-103
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 1 MIKMTNVYKEYPNGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLAERDVPYFRRQ 80
Cdd:TIGR02673 1 MIEFHNVSKAYPGGVAALHDVSLHIRKGEFLFLTGPSGAGKTTLLKLLYGALTPSRGQVRIAGEDVNRLRGRQLPLLRRR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 81 LGVIFQDFKLLPKLTVYENVSFALEVIEEEPDAIRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIVNRPKVVI 160
Cdd:TIGR02673 81 IGVVFQDFRLLPDRTVYENVALPLEVRGKKEREIQRRVGAALRQVGLEHKADAFPEQLSGGEQQRVAIARAIVNSPPLLL 160
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 446516975 161 ADEPTGNLDIETALDIMNIFTRINERGTTIVMATHNADIVNTIRHRVIAIEGGK 214
Cdd:TIGR02673 161 ADEPTGNLDPDLSERILDLLKRLNKRGTTVIVATHDLSLVDRVAHRVIILDDGR 214
|
|
| LolD |
COG1136 |
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis]; |
1-219 |
4.31e-92 |
|
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440751 [Multi-domain] Cd Length: 227 Bit Score: 269.61 E-value: 4.31e-92
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 1 MIKMTNVYKEYPNGM---KAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLAERDVPYF 77
Cdd:COG1136 4 LLELRNLTKSYGTGEgevTALRGVSLSIEAGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVLIDGQDISSLSERELARL 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 78 RRQ-LGVIFQDFKLLPKLTVYENVSFALEVIEEEPDAIRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIVNRP 156
Cdd:COG1136 84 RRRhIGFVFQFFNLLPELTALENVALPLLLAGVSRKERRERARELLERVGLGDRLDHRPSQLSGGQQQRVAIARALVNRP 163
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446516975 157 KVVIADEPTGNLDIETALDIMNIFTRIN-ERGTTIVMATHNADIVNtIRHRVIAIEGGKIVRDE 219
Cdd:COG1136 164 KLILADEPTGNLDSKTGEEVLELLRELNrELGTTIVMVTHDPELAA-RADRVIRLRDGRIVSDE 226
|
|
| ABC_MJ0796_LolCDE_FtsE |
cd03255 |
ATP-binding cassette domain of the transporters involved in export of lipoprotein and ... |
2-215 |
2.31e-91 |
|
ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and Cell division ATP-binding protein FtsE; This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.
Pssm-ID: 213222 [Multi-domain] Cd Length: 218 Bit Score: 267.43 E-value: 2.31e-91
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 2 IKMTNVYKEYPNGMK---AIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLAERDVPYFR 78
Cdd:cd03255 1 IELKNLSKTYGGGGEkvqALKGVSLSIEKGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVRVDGTDISKLSEKELAAFR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 79 R-QLGVIFQDFKLLPKLTVYENVSFALEVIEEEPDAIRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIVNRPK 157
Cdd:cd03255 81 RrHIGFVFQSFNLLPDLTALENVELPLLLAGVPKKERRERAEELLERVGLGDRLNHYPSELSGGQQQRVAIARALANDPK 160
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 446516975 158 VVIADEPTGNLDIETALDIMNIFTRIN-ERGTTIVMATHNADIVNtIRHRVIAIEGGKI 215
Cdd:cd03255 161 IILADEPTGNLDSETGKEVMELLRELNkEAGTTIVVVTHDPELAE-YADRIIELRDGKI 218
|
|
| AbcC |
COG1135 |
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism]; |
1-216 |
1.01e-77 |
|
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 440750 [Multi-domain] Cd Length: 339 Bit Score: 236.90 E-value: 1.01e-77
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 1 MIKMTNVYKEYPNGMKAIAGL---TVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLAERDVPYF 77
Cdd:COG1135 1 MIELENLSKTFPTKGGPVTALddvSLTIEKGEIFGIIGYSGAGKSTLIRCINLLERPTSGSVLVDGVDLTALSERELRAA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 78 RRQLGVIFQDFKLLPKLTVYENVSFALEVIEEEPDAIRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIVNRPK 157
Cdd:COG1135 81 RRKIGMIFQHFNLLSSRTVAENVALPLEIAGVPKAEIRKRVAELLELVGLSDKADAYPSQLSGGQKQRVGIARALANNPK 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 158 VVIADEPTGNLDIETALDIMNIFTRINER-GTTIVMATHNADIVNTIRHRVIAIEGGKIV 216
Cdd:COG1135 161 VLLCDEATSALDPETTRSILDLLKDINRElGLTIVLITHEMDVVRRICDRVAVLENGRIV 220
|
|
| ABC_MetN_methionine_transporter |
cd03258 |
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ... |
1-216 |
3.60e-75 |
|
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ABC-type transporter encoded by metN of the metNPQ operon in Bacillus subtilis that is involved in methionine transport. Other members of this system include the MetP permease and the MetQ substrate binding protein. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213225 [Multi-domain] Cd Length: 233 Bit Score: 227.08 E-value: 3.60e-75
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 1 MIKMTNVYKEYPNG---MKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLAERDVPYF 77
Cdd:cd03258 1 MIELKNVSKVFGDTggkVTALKDVSLSVPKGEIFGIIGRSGAGKSTLIRCINGLERPTSGSVLVDGTDLTLLSGKELRKA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 78 RRQLGVIFQDFKLLPKLTVYENVSFALEVIEEEPDAIRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIVNRPK 157
Cdd:cd03258 81 RRRIGMIFQHFNLLSSRTVFENVALPLEIAGVPKAEIEERVLELLELVGLEDKADAYPAQLSGGQKQRVGIARALANNPK 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 158 VVIADEPTGNLDIETALDIMNIFTRIN-ERGTTIVMATHNADIVNTIRHRVIAIEGGKIV 216
Cdd:cd03258 161 VLLCDEATSALDPETTQSILALLRDINrELGLTIVLITHEMEVVKRICDRVAVMEKGEVV 220
|
|
| PhnC |
COG3638 |
ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and ... |
1-218 |
8.68e-72 |
|
ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 442855 [Multi-domain] Cd Length: 249 Bit Score: 218.77 E-value: 8.68e-72
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 1 MIKMTNVYKEYPNGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLAERDVPYFRRQ 80
Cdd:COG3638 2 MLELRNLSKRYPGGTPALDDVSLEIERGEFVALIGPSGAGKSTLLRCLNGLVEPTSGEILVDGQDVTALRGRALRRLRRR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 81 LGVIFQDFKLLPKLTVYENV------------SFALEVIEEEpdaiRERVTEVLGLVGLEDRADALPSELSGGEQQRVAI 148
Cdd:COG3638 82 IGMIFQQFNLVPRLSVLTNVlagrlgrtstwrSLLGLFPPED----RERALEALERVGLADKAYQRADQLSGGQQQRVAI 157
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446516975 149 ARAIVNRPKVVIADEPTGNLDIETALDIMNIFTRIN-ERGTTIVMATHNADIVNTIRHRVIAIEGGKIVRD 218
Cdd:COG3638 158 ARALVQEPKLILADEPVASLDPKTARQVMDLLRRIArEDGITVVVNLHQVDLARRYADRIIGLRDGRVVFD 228
|
|
| EcfA2 |
COG1122 |
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and ... |
2-218 |
1.07e-70 |
|
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and metabolism, General function prediction only];
Pssm-ID: 440739 [Multi-domain] Cd Length: 230 Bit Score: 215.27 E-value: 1.07e-70
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 2 IKMTNVYKEYPNGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIetlAERDVPYFRRQL 81
Cdd:COG1122 1 IELENLSFSYPGGTPALDDVSLSIEKGEFVAIIGPNGSGKSTLLRLLNGLLKPTSGEVLVDGKDI---TKKNLRELRRKV 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 82 GVIFQDfkllP-----KLTVYENVSFALEVIEEEPDAIRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIVNRP 156
Cdd:COG1122 78 GLVFQN----PddqlfAPTVEEDVAFGPENLGLPREEIRERVEEALELVGLEHLADRPPHELSGGQKQRVAIAGVLAMEP 153
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446516975 157 KVVIADEPTGNLDIETALDIMNIFTRINERGTTIVMATHNADIVNTIRHRVIAIEGGKIVRD 218
Cdd:COG1122 154 EVLVLDEPTAGLDPRGRRELLELLKRLNKEGKTVIIVTHDLDLVAELADRVIVLDDGRIVAD 215
|
|
| metN |
PRK11153 |
DL-methionine transporter ATP-binding subunit; Provisional |
1-216 |
8.12e-69 |
|
DL-methionine transporter ATP-binding subunit; Provisional
Pssm-ID: 236863 [Multi-domain] Cd Length: 343 Bit Score: 214.28 E-value: 8.12e-69
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 1 MIKMTNVYKEYPNGMKAIAGLT-VN--IKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLAERDVPYF 77
Cdd:PRK11153 1 MIELKNISKVFPQGGRTIHALNnVSlhIPAGEIFGVIGASGAGKSTLIRCINLLERPTSGRVLVDGQDLTALSEKELRKA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 78 RRQLGVIFQDFKLLPKLTVYENVSFALEVIEEEPDAIRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIVNRPK 157
Cdd:PRK11153 81 RRQIGMIFQHFNLLSSRTVFDNVALPLELAGTPKAEIKARVTELLELVGLSDKADRYPAQLSGGQKQRVAIARALASNPK 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 158 VVIADEPTGNLDIETALDIMNIFTRINER-GTTIVMATHNADIVNTIRHRVIAIEGGKIV 216
Cdd:PRK11153 161 VLLCDEATSALDPATTRSILELLKDINRElGLTIVLITHEMDVVKRICDRVAVIDAGRLV 220
|
|
| YbbA |
COG4181 |
Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase ... |
1-219 |
1.09e-67 |
|
Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 443338 [Multi-domain] Cd Length: 233 Bit Score: 208.06 E-value: 1.09e-67
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 1 MIKMTNVYKEYPNGMKAIA---GLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLAERDVPYF 77
Cdd:COG4181 8 IIELRGLTKTVGTGAGELTilkGISLEVEAGESVAIVGASGSGKSTLLGLLAGLDRPTSGTVRLAGQDLFALDEDARARL 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 78 RRQ-LGVIFQDFKLLPKLTVYENVSFALEvIEEEPDAiRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIVNRP 156
Cdd:COG4181 88 RARhVGFVFQSFQLLPTLTALENVMLPLE-LAGRRDA-RARARALLERVGLGHRLDHYPAQLSGGEQQRVALARAFATEP 165
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446516975 157 KVVIADEPTGNLDIETALDIMN-IFTRINERGTTIVMATHNADIVNtiR-HRVIAIEGGKIVRDE 219
Cdd:COG4181 166 AILFADEPTGNLDAATGEQIIDlLFELNRERGTTLVLVTHDPALAA--RcDRVLRLRAGRLVEDT 228
|
|
| TauB |
COG1116 |
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion ... |
1-196 |
2.92e-66 |
|
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440733 [Multi-domain] Cd Length: 260 Bit Score: 205.32 E-value: 2.92e-66
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 1 MIKMTNVYKEYP---NGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLaerdvpyf 77
Cdd:COG1116 7 ALELRGVSKRFPtggGGVTALDDVSLTVAAGEFVALVGPSGCGKSTLLRLIAGLEKPTSGEVLVDGKPVTGP-------- 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 78 RRQLGVIFQDFKLLPKLTVYENVSFALEVIEEEPDAIRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIVNRPK 157
Cdd:COG1116 79 GPDRGVVFQEPALLPWLTVLDNVALGLELRGVPKAERRERARELLELVGLAGFEDAYPHQLSGGMRQRVAIARALANDPE 158
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 446516975 158 VVIADEPTGNLDIETALDIMNIFTRI-NERGTTIVMATHN 196
Cdd:COG1116 159 VLLMDEPFGALDALTRERLQDELLRLwQETGKTVLFVTHD 198
|
|
| PRK10908 |
PRK10908 |
cell division ATP-binding protein FtsE; |
1-216 |
4.12e-65 |
|
cell division ATP-binding protein FtsE;
Pssm-ID: 182829 [Multi-domain] Cd Length: 222 Bit Score: 200.87 E-value: 4.12e-65
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 1 MIKMTNVYKEYPNGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLAERDVPYFRRQ 80
Cdd:PRK10908 1 MIRFEHVSKAYLGGRQALQGVTFHMRPGEMAFLTGHSGAGKSTLLKLICGIERPSAGKIWFSGHDITRLKNREVPFLRRQ 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 81 LGVIFQDFKLLPKLTVYENVSFALEVIEEEPDAIRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIVNRPKVVI 160
Cdd:PRK10908 81 IGMIFQDHHLLMDRTVYDNVAIPLIIAGASGDDIRRRVSAALDKVGLLDKAKNFPIQLSGGEQQRVGIARAVVNKPAVLL 160
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 446516975 161 ADEPTGNLDIETALDIMNIFTRINERGTTIVMATHNADIVNTIRHRVIAIEGGKIV 216
Cdd:PRK10908 161 ADEPTGNLDDALSEGILRLFEEFNRVGVTVLMATHDIGLISRRSYRMLTLSDGHLH 216
|
|
| ABC_PhnC_transporter |
cd03256 |
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; ... |
2-218 |
7.20e-64 |
|
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Phosphonates are a class of organophosphorus compounds characterized by a chemically stable carbon-to-phosphorus (C-P) bond. Phosphonates are widespread among naturally occurring compounds in all kingdoms of wildlife, but only prokaryotic microorganisms are able to cleave this bond. Certain bacteria such as E. coli can use alkylphosphonates as a phosphorus source. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213223 [Multi-domain] Cd Length: 241 Bit Score: 198.56 E-value: 7.20e-64
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 2 IKMTNVYKEYPNGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLAERDVPYFRRQL 81
Cdd:cd03256 1 IEVENLSKTYPNGKKALKDVSLSINPGEFVALIGPSGAGKSTLLRCLNGLVEPTSGSVLIDGTDINKLKGKALRQLRRQI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 82 GVIFQDFKLLPKLTVYENV------------SFALEVIEEEpdaiRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIA 149
Cdd:cd03256 81 GMIFQQFNLIERLSVLENVlsgrlgrrstwrSLFGLFPKEE----KQRALAALERVGLLDKAYQRADQLSGGQQQRVAIA 156
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 150 RAIVNRPKVVIADEPTGNLDIETALDIMNIFTRIN-ERGTTIVMATHNADIVNTIRHRVIAIEGGKIVRD 218
Cdd:cd03256 157 RALMQQPKLILADEPVASLDPASSRQVMDLLKRINrEEGITVIVSLHQVDLAREYADRIVGLKDGRIVFD 226
|
|
| PotA |
COG3842 |
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport ... |
1-216 |
2.32e-62 |
|
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443052 [Multi-domain] Cd Length: 353 Bit Score: 198.01 E-value: 2.32e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 1 MIKMTNVYKEYpNGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIEtlaerDVPYFRRQ 80
Cdd:COG3842 5 ALELENVSKRY-GDVTALDDVSLSIEPGEFVALLGPSGCGKTTLLRMIAGFETPDSGRILLDGRDVT-----GLPPEKRN 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 81 LGVIFQDFKLLPKLTVYENVSFALEVIEEEPDAIRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIVNRPKVVI 160
Cdd:COG3842 79 VGMVFQDYALFPHLTVAENVAFGLRMRGVPKAEIRARVAELLELVGLEGLADRYPHQLSGGQQQRVALARALAPEPRVLL 158
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 161 ADEPTGNLD----IETALDIMNIftrINERGTTIVMATHNADIVNTIRHRVIAIEGGKIV 216
Cdd:COG3842 159 LDEPLSALDaklrEEMREELRRL---QRELGITFIYVTHDQEEALALADRIAVMNDGRIE 215
|
|
| CcmA |
COG1131 |
ABC-type multidrug transport system, ATPase component [Defense mechanisms]; |
2-218 |
3.70e-62 |
|
ABC-type multidrug transport system, ATPase component [Defense mechanisms];
Pssm-ID: 440746 [Multi-domain] Cd Length: 236 Bit Score: 193.74 E-value: 3.70e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 2 IKMTNVYKEYPNGmKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLAERdvpyFRRQL 81
Cdd:COG1131 1 IEVRGLTKRYGDK-TALDGVSLTVEPGEIFGLLGPNGAGKTTTIRMLLGLLRPTSGEVRVLGEDVARDPAE----VRRRI 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 82 GVIFQDFKLLPKLTVYENVSFALEVIEEEPDAIRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIVNRPKVVIA 161
Cdd:COG1131 76 GYVPQEPALYPDLTVRENLRFFARLYGLPRKEARERIDELLELFGLTDAADRKVGTLSGGMKQRLGLALALLHDPELLIL 155
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 446516975 162 DEPTGNLDIETALDIMNIFTRINERGTTIVMATHNADIVNTIRHRVIAIEGGKIVRD 218
Cdd:COG1131 156 DEPTSGLDPEARRELWELLRELAAEGKTVLLSTHYLEEAERLCDRVAIIDKGRIVAD 212
|
|
| ABC_NrtD_SsuB_transporters |
cd03293 |
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ... |
2-198 |
7.71e-61 |
|
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ATP-binding subunits of the bacterial ABC-type nitrate and sulfonate transport systems, respectively. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213260 [Multi-domain] Cd Length: 220 Bit Score: 189.99 E-value: 7.71e-61
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 2 IKMTNVYKEYPNGM---KAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGltietlaeRDVPYFR 78
Cdd:cd03293 1 LEVRNVSKTYGGGGgavTALEDISLSVEEGEFVALVGPSGCGKSTLLRIIAGLERPTSGEVLVDG--------EPVTGPG 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 79 RQLGVIFQDFKLLPKLTVYENVSFALEVIEEEPDAIRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIVNRPKV 158
Cdd:cd03293 73 PDRGYVFQQDALLPWLTVLDNVALGLELQGVPKAEARERAEELLELVGLSGFENAYPHQLSGGMRQRVALARALAVDPDV 152
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 446516975 159 VIADEPTGNLDIETALDIMNIFTRI-NERGTTIVMATHNAD 198
Cdd:cd03293 153 LLLDEPFSALDALTREQLQEELLDIwRETGKTVLLVTHDID 193
|
|
| ABC_cobalt_CbiO_domain1 |
cd03225 |
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ... |
6-214 |
7.85e-61 |
|
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.
Pssm-ID: 213192 [Multi-domain] Cd Length: 211 Bit Score: 189.60 E-value: 7.85e-61
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 6 NVYKEYPNGMK-AIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLAERDvpyFRRQLGVI 84
Cdd:cd03225 4 NLSFSYPDGARpALDDISLTIKKGEFVLIVGPNGSGKSTLLRLLNGLLGPTSGEVLVDGKDLTKLSLKE---LRRKVGLV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 85 FQDFKL-LPKLTVYENVSFALEVIEEEPDAIRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIVNRPKVVIADE 163
Cdd:cd03225 81 FQNPDDqFFGPTVEEEVAFGLENLGLPEEEIEERVEEALELVGLEGLRDRSPFTLSGGQKQRVAIAGVLAMDPDILLLDE 160
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 446516975 164 PTGNLDIETALDIMNIFTRINERGTTIVMATHNADIVNTIRHRVIAIEGGK 214
Cdd:cd03225 161 PTAGLDPAGRRELLELLKKLKAEGKTIIIVTHDLDLLLELADRVIVLEDGK 211
|
|
| MlaF |
COG1127 |
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall ... |
1-221 |
2.10e-60 |
|
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440744 [Multi-domain] Cd Length: 241 Bit Score: 189.42 E-value: 2.10e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 1 MIKMTNVYKEYpNGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLAERDVPYFRRQ 80
Cdd:COG1127 5 MIEVRNLTKSF-GDRVVLDGVSLDVPRGEILAIIGGSGSGKSVLLKLIIGLLRPDSGEILVDGQDITGLSEKELYELRRR 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 81 LGVIFQDFKLLPKLTVYENVSFALEVIEEEPDA-IRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIVNRPKVV 159
Cdd:COG1127 84 IGMLFQGGALFDSLTVFENVAFPLREHTDLSEAeIRELVLEKLELVGLPGAADKMPSELSGGMRKRVALARALALDPEIL 163
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446516975 160 IADEPTGNLDIETALDIMNIFTRINER-GTTIVMATHNADIVNTIRHRVIAIEGGKIV----RDEIE 221
Cdd:COG1127 164 LYDEPTAGLDPITSAVIDELIRELRDElGLTSVVVTHDLDSAFAIADRVAVLADGKIIaegtPEELL 230
|
|
| ABC_PotA_N |
cd03300 |
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and ... |
2-216 |
2.30e-60 |
|
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and the ATPase component of the spermidine/putrescine-preferential uptake system consisting of PotA, -B, -C, and -D. PotA has two domains with the N-terminal domain containing the ATPase activity and the residues required for homodimerization with PotA and heterdimerization with PotB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213267 [Multi-domain] Cd Length: 232 Bit Score: 189.37 E-value: 2.30e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 2 IKMTNVYKEYpNGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIEtlaerDVPYFRRQL 81
Cdd:cd03300 1 IELENVSKFY-GGFVALDGVSLDIKEGEFFTLLGPSGCGKTTLLRLIAGFETPTSGEILLDGKDIT-----NLPPHKRPV 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 82 GVIFQDFKLLPKLTVYENVSFALEVIEEEPDAIRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIVNRPKVVIA 161
Cdd:cd03300 75 NTVFQNYALFPHLTVFENIAFGLRLKKLPKAEIKERVAEALDLVQLEGYANRKPSQLSGGQQQRVAIARALVNEPKVLLL 154
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 446516975 162 DEPTGNLDI----ETALDIMNIFTRInerGTTIVMATHNADIVNTIRHRVIAIEGGKIV 216
Cdd:cd03300 155 DEPLGALDLklrkDMQLELKRLQKEL---GITFVFVTHDQEEALTMSDRIAVMNKGKIQ 210
|
|
| GsiA |
COG1123 |
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ... |
1-216 |
2.81e-60 |
|
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440740 [Multi-domain] Cd Length: 514 Bit Score: 197.05 E-value: 2.81e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 1 MIKMTNVYKEYP----NGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLAERDVPY 76
Cdd:COG1123 260 LLEVRNLSKRYPvrgkGGVRAVDDVSLTLRRGETLGLVGESGSGKSTLARLLLGLLRPTSGSILFDGKDLTKLSRRSLRE 339
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 77 FRRQLGVIFQD-FK-LLPKLTVYENVSFALEVIEEEPDA-IRERVTEVLGLVGL-EDRADALPSELSGGEQQRVAIARAI 152
Cdd:COG1123 340 LRRRVQMVFQDpYSsLNPRMTVGDIIAEPLRLHGLLSRAeRRERVAELLERVGLpPDLADRYPHELSGGQRQRVAIARAL 419
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446516975 153 VNRPKVVIADEPTGNLDIETALDIMNIFTRIN-ERGTTIVMATHNADIVNTIRHRVIAIEGGKIV 216
Cdd:COG1123 420 ALEPKLLILDEPTSALDVSVQAQILNLLRDLQrELGLTYLFISHDLAVVRYIADRVAVMYDGRIV 484
|
|
| ABC_HisP_GlnQ |
cd03262 |
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ... |
2-215 |
1.80e-59 |
|
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ATP-binding components of the bacterial periplasmic histidine and glutamine permeases, respectively. Histidine permease is a multi-subunit complex containing the HisQ and HisM integral membrane subunits and two copies of HisP. HisP has properties intermediate between those of integral and peripheral membrane proteins and is accessible from both sides of the membrane, presumably by its interaction with HisQ and HisM. The two HisP subunits form a homodimer within the complex. The domain structure of the amino acid uptake systems is typical for prokaryotic extracellular solute binding protein-dependent uptake systems. All of the amino acid uptake systems also have at least one, and in a few cases, two extracellular solute binding proteins located in the periplasm of Gram-negative bacteria, or attached to the cell membrane of Gram-positive bacteria. The best-studied member of the PAAT (polar amino acid transport) family is the HisJQMP system of S. typhimurium, where HisJ is the extracellular solute binding proteins and HisP is the ABC protein.
Pssm-ID: 213229 [Multi-domain] Cd Length: 213 Bit Score: 186.20 E-value: 1.80e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 2 IKMTNVYKEYpNGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIeTLAERDVPYFRRQL 81
Cdd:cd03262 1 IEIKNLHKSF-GDFHVLKGIDLTVKKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTIIIDGLKL-TDDKKNINELRQKV 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 82 GVIFQDFKLLPKLTVYENVSFAL-EVIEEEPDAIRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIVNRPKVVI 160
Cdd:cd03262 79 GMVFQQFNLFPHLTVLENITLAPiKVKGMSKAEAEERALELLEKVGLADKADAYPAQLSGGQQQRVAIARALAMNPKVML 158
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 446516975 161 ADEPTGNLDIETALDIMNIFTRINERGTTIVMATHNADIVNTIRHRVIAIEGGKI 215
Cdd:cd03262 159 FDEPTSALDPELVGEVLDVMKDLAEEGMTMVVVTHEMGFAREVADRVIFMDDGRI 213
|
|
| ABC_Carb_Solutes_like |
cd03259 |
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is ... |
2-216 |
2.65e-59 |
|
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is comprised of proteins involved in the transport of apparently unrelated solutes and proteins specific for di- and oligosaccharides and polyols. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213226 [Multi-domain] Cd Length: 213 Bit Score: 185.80 E-value: 2.65e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 2 IKMTNVYKEYpNGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLAERdvpyfRRQL 81
Cdd:cd03259 1 LELKGLSKTY-GSVRALDDLSLTVEPGEFLALLGPSGCGKTTLLRLIAGLERPDSGEILIDGRDVTGVPPE-----RRNI 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 82 GVIFQDFKLLPKLTVYENVSFALEVIEEEPDAIRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIVNRPKVVIA 161
Cdd:cd03259 75 GMVFQDYALFPHLTVAENIAFGLKLRGVPKAEIRARVRELLELVGLEGLLNRYPHELSGGQQQRVALARALAREPSLLLL 154
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 446516975 162 DEPTGNLDIETALDIMNIFTRI-NERGTTIVMATHNADIVNTIRHRVIAIEGGKIV 216
Cdd:cd03259 155 DEPLSALDAKLREELREELKELqRELGITTIYVTHDQEEALALADRIAVMNEGRIV 210
|
|
| ABC_NikE_OppD_transporters |
cd03257 |
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter ... |
1-216 |
4.43e-59 |
|
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter subfamily specific for the transport of dipeptides, oligopeptides (OppD), and nickel (NikDE). The NikABCDE system of E. coli belongs to this family and is composed of the periplasmic binding protein NikA, two integral membrane components (NikB and NikC), and two ATPase (NikD and NikE). The NikABCDE transporter is synthesized under anaerobic conditions to meet the increased demand for nickel resulting from hydrogenase synthesis. The molecular mechanism of nickel uptake in many bacteria and most archaea is not known. Many other members of this ABC family are also involved in the uptake of dipeptides and oligopeptides. The oligopeptide transport system (Opp) is a five-component ABC transport composed of a membrane-anchored substrate binding proteins (SRP), OppA, two transmembrane proteins, OppB and OppC, and two ATP-binding domains, OppD and OppF.
Pssm-ID: 213224 [Multi-domain] Cd Length: 228 Bit Score: 185.79 E-value: 4.43e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 1 MIKMTNVYKEYPNG---MKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLAERDVPYF 77
Cdd:cd03257 1 LLEVKNLSVSFPTGggsVKALDDVSFSIKKGETLGLVGESGSGKSTLARAILGLLKPTSGSIIFDGKDLLKLSRRLRKIR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 78 RRQLGVIFQD--FKLLPKLTVYENVSFALEV--IEEEPDAIRERVTEVLGLVGL-EDRADALPSELSGGEQQRVAIARAI 152
Cdd:cd03257 81 RKEIQMVFQDpmSSLNPRMTIGEQIAEPLRIhgKLSKKEARKEAVLLLLVGVGLpEEVLNRYPHELSGGQRQRVAIARAL 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446516975 153 VNRPKVVIADEPTGNLDIETALDIMNIFTRI-NERGTTIVMATHNADIVNTIRHRVIAIEGGKIV 216
Cdd:cd03257 161 ALNPKLLIADEPTSALDVSVQAQILDLLKKLqEELGLTLLFITHDLGVVAKIADRVAVMYAGKIV 225
|
|
| ABC_phnC |
TIGR02315 |
phosphonate ABC transporter, ATP-binding protein; Phosphonates are a class of ... |
1-218 |
6.88e-59 |
|
phosphonate ABC transporter, ATP-binding protein; Phosphonates are a class of phosphorus-containing organic compound with a stable direct C-P bond rather than a C-O-P linkage. A number of bacterial species have operons, typically about 14 genes in size, with genes for ATP-dependent transport of phosphonates, degradation, and regulation of the expression of the system. Members of this protein family are the ATP-binding cassette component of tripartite ABC transporters of phosphonates. [Transport and binding proteins, Anions]
Pssm-ID: 131368 [Multi-domain] Cd Length: 243 Bit Score: 185.96 E-value: 6.88e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 1 MIKMTNVYKEYPNGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLAERDVPYFRRQ 80
Cdd:TIGR02315 1 MLEVENLSKVYPNGKQALKNINLNINPGEFVAIIGPSGAGKSTLLRCINRLVEPSSGSILLEGTDITKLRGKKLRKLRRR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 81 LGVIFQDFKLLPKLTVYENV--------SFALEVIEEEPDAIRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAI 152
Cdd:TIGR02315 81 IGMIFQHYNLIERLTVLENVlhgrlgykPTWRSLLGRFSEEDKERALSALERVGLADKAYQRADQLSGGQQQRVAIARAL 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446516975 153 VNRPKVVIADEPTGNLDIETALDIMNIFTRIN-ERGTTIVMATHNADIVNTIRHRVIAIEGGKIVRD 218
Cdd:TIGR02315 161 AQQPDLILADEPIASLDPKTSKQVMDYLKRINkEDGITVIINLHQVDLAKKYADRIVGLKAGEIVFD 227
|
|
| GlnQ |
COG1126 |
ABC-type polar amino acid transport system, ATPase component [Amino acid transport and ... |
1-216 |
7.20e-58 |
|
ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 440743 [Multi-domain] Cd Length: 239 Bit Score: 182.89 E-value: 7.20e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 1 MIKMTNVYKEYpNGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIeTLAERDVPYFRRQ 80
Cdd:COG1126 1 MIEIENLHKSF-GDLEVLKGISLDVEKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTITVDGEDL-TDSKKDINKLRRK 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 81 LGVIFQDFKLLPKLTVYENVSFALEVIEEEP-DAIRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIVNRPKVV 159
Cdd:COG1126 79 VGMVFQQFNLFPHLTVLENVTLAPIKVKKMSkAEAEERAMELLERVGLADKADAYPAQLSGGQQQRVAIARALAMEPKVM 158
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 160 IADEPTGNLDIETA---LDIMnifTRINERGTTIVMATHNADIVNTIRHRVIAIEGGKIV 216
Cdd:COG1126 159 LFDEPTSALDPELVgevLDVM---RDLAKEGMTMVVVTHEMGFAREVADRVVFMDGGRIV 215
|
|
| MalK |
COG3839 |
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism]; ... |
1-216 |
4.77e-56 |
|
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism];
Pssm-ID: 443050 [Multi-domain] Cd Length: 352 Bit Score: 181.81 E-value: 4.77e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 1 MIKMTNVYKEYpNGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLAERDvpyfrRQ 80
Cdd:COG3839 3 SLELENVSKSY-GGVEALKDIDLDIEDGEFLVLLGPSGCGKSTLLRMIAGLEDPTSGEILIGGRDVTDLPPKD-----RN 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 81 LGVIFQDFKLLPKLTVYENVSFALEVIEEEPDAIRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIVNRPKVVI 160
Cdd:COG3839 77 IAMVFQSYALYPHMTVYENIAFPLKLRKVPKAEIDRRVREAAELLGLEDLLDRKPKQLSGGQRQRVALGRALVREPKVFL 156
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 161 ADEPTGNLD----IETALDIMNIFtriNERGTTIVMATHNADIVNTIRHRVIAIEGGKIV 216
Cdd:COG3839 157 LDEPLSNLDaklrVEMRAEIKRLH---RRLGTTTIYVTHDQVEAMTLADRIAVMNDGRIQ 213
|
|
| ABC_Org_Solvent_Resistant |
cd03261 |
ATP-binding cassette transport system involved in resistance to organic solvents; ABC ... |
2-216 |
1.68e-55 |
|
ATP-binding cassette transport system involved in resistance to organic solvents; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213228 [Multi-domain] Cd Length: 235 Bit Score: 176.92 E-value: 1.68e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 2 IKMTNVYKEYpnGMKAI-AGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLAERDVPYFRRQ 80
Cdd:cd03261 1 IELRGLTKSF--GGRTVlKGVDLDVRRGEILAIIGPSGSGKSTLLRLIVGLLRPDSGEVLIDGEDISGLSEAELYRLRRR 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 81 LGVIFQDFKLLPKLTVYENVSFALEVIEEEPDA-IRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIVNRPKVV 159
Cdd:cd03261 79 MGMLFQSGALFDSLTVFENVAFPLREHTRLSEEeIREIVLEKLEAVGLRGAEDLYPAELSGGMKKRVALARALALDPELL 158
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 446516975 160 IADEPTGNLDIETALDIMNIFTRINER-GTTIVMATHNADIVNTIRHRVIAIEGGKIV 216
Cdd:cd03261 159 LYDEPTAGLDPIASGVIDDLIRSLKKElGLTSIMVTHDLDTAFAIADRIAVLYDGKIV 216
|
|
| ABC_Class3 |
cd03229 |
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is ... |
2-214 |
2.09e-53 |
|
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is comprised of all BPD (Binding Protein Dependent) systems that are largely represented in archaea and eubacteria and are primarily involved in scavenging solutes from the environment. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213196 [Multi-domain] Cd Length: 178 Bit Score: 169.68 E-value: 2.09e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 2 IKMTNVYKEYpNGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLaERDVPYFRRQL 81
Cdd:cd03229 1 LELKNVSKRY-GQKTVLNDVSLNIEAGEIVALLGPSGSGKSTLLRCIAGLEEPDSGSILIDGEDLTDL-EDELPPLRRRI 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 82 GVIFQDFKLLPKLTVYENVSFAlevieeepdairervtevlglvgledradalpseLSGGEQQRVAIARAIVNRPKVVIA 161
Cdd:cd03229 79 GMVFQDFALFPHLTVLENIALG----------------------------------LSGGQQQRVALARALAMDPDVLLL 124
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 446516975 162 DEPTGNLDIETALDIMNIFTRINER-GTTIVMATHNADIVNTIRHRVIAIEGGK 214
Cdd:cd03229 125 DEPTSALDPITRREVRALLKSLQAQlGITVVLVTHDLDEAARLADRVVVLRDGK 178
|
|
| glnQ |
PRK09493 |
glutamine ABC transporter ATP-binding protein GlnQ; |
1-218 |
3.85e-53 |
|
glutamine ABC transporter ATP-binding protein GlnQ;
Pssm-ID: 181906 [Multi-domain] Cd Length: 240 Bit Score: 171.04 E-value: 3.85e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 1 MIKMTNVYKEYpNGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETlAERDVPYFRRQ 80
Cdd:PRK09493 1 MIEFKNVSKHF-GPTQVLHNIDLNIDQGEVVVIIGPSGSGKSTLLRCINKLEEITSGDLIVDGLKVND-PKVDERLIRQE 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 81 LGVIFQDFKLLPKLTVYENVSFA-LEVIEEEPDAIRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIVNRPKVV 159
Cdd:PRK09493 79 AGMVFQQFYLFPHLTALENVMFGpLRVRGASKEEAEKQARELLAKVGLAERAHHYPSELSGGQQQRVAIARALAVKPKLM 158
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 446516975 160 IADEPTGNLDIETALDIMNIFTRINERGTTIVMATHNADIVNTIRHRVIAIEGGKIVRD 218
Cdd:PRK09493 159 LFDEPTSALDPELRHEVLKVMQDLAEEGMTMVIVTHEIGFAEKVASRLIFIDKGRIAED 217
|
|
| ABC_OpuCA_Osmoprotection |
cd03295 |
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding ... |
2-216 |
5.80e-53 |
|
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing in a hyperosmolar environment. ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition, to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213262 [Multi-domain] Cd Length: 242 Bit Score: 170.56 E-value: 5.80e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 2 IKMTNVYKEYPNGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGltiETLAERDVPYFRRQL 81
Cdd:cd03295 1 IEFENVTKRYGGGKKAVNNLNLEIAKGEFLVLIGPSGSGKTTTMKMINRLIEPTSGEIFIDG---EDIREQDPVELRRKI 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 82 GVIFQDFKLLPKLTVYENVSFALEVIEEEPDAIRERVTEVLGLVGLEDR--ADALPSELSGGEQQRVAIARAIVNRPKVV 159
Cdd:cd03295 78 GYVIQQIGLFPHMTVEENIALVPKLLKWPKEKIRERADELLALVGLDPAefADRYPHELSGGQQQRVGVARALAADPPLL 157
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 446516975 160 IADEPTGNLDIETALDIMNIFTRINER-GTTIVMATHNADIVNTIRHRVIAIEGGKIV 216
Cdd:cd03295 158 LMDEPFGALDPITRDQLQEEFKRLQQElGKTIVFVTHDIDEAFRLADRIAIMKNGEIV 215
|
|
| NatA |
COG4555 |
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, ... |
1-219 |
1.02e-52 |
|
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, Inorganic ion transport and metabolism];
Pssm-ID: 443618 [Multi-domain] Cd Length: 243 Bit Score: 170.04 E-value: 1.02e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 1 MIKMTNVYKEYpNGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTietlAERDVPYFRRQ 80
Cdd:COG4555 1 MIEVENLSKKY-GKVPALKDVSFTAKDGEITGLLGPNGAGKTTLLRMLAGLLKPDSGSILIDGED----VRKEPREARRQ 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 81 LGVIFQDFKLLPKLTVYENVSFALEVIEEEPDAIRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIVNRPKVVI 160
Cdd:COG4555 76 IGVLPDERGLYDRLTVRENIRYFAELYGLFDEELKKRIEELIELLGLEEFLDRRVGELSTGMKKKVALARALVHDPKVLL 155
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 446516975 161 ADEPTGNLDIETALDIMNIFTRINERGTTIVMATHNADIVNTIRHRVIAIEGGKIVRDE 219
Cdd:COG4555 156 LDEPTNGLDVMARRLLREILRALKKEGKTVLFSSHIMQEVEALCDRVVILHKGKVVAQG 214
|
|
| DppF |
COG1124 |
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ... |
1-218 |
1.18e-51 |
|
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];
Pssm-ID: 440741 [Multi-domain] Cd Length: 248 Bit Score: 167.29 E-value: 1.18e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 1 MIKMTNVYKEYPNGMK---AIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLAERDvpyF 77
Cdd:COG1124 1 MLEVRNLSVSYGQGGRrvpVLKDVSLEVAPGESFGLVGESGSGKSTLLRALAGLERPWSGEVTFDGRPVTRRRRKA---F 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 78 RRQLGVIFQDFK--LLPKLTVYENVSFALEVIEEepDAIRERVTEVLGLVGLEDR-ADALPSELSGGEQQRVAIARAIVN 154
Cdd:COG1124 78 RRRVQMVFQDPYasLHPRHTVDRILAEPLRIHGL--PDREERIAELLEQVGLPPSfLDRYPHQLSGGQRQRVAIARALIL 155
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446516975 155 RPKVVIADEPTGNLDIETALDIMNIFTRIN-ERGTTIVMATHNADIVNTIRHRVIAIEGGKIVRD 218
Cdd:COG1124 156 EPELLLLDEPTSALDVSVQAEILNLLKDLReERGLTYLFVSHDLAVVAHLCDRVAVMQNGRIVEE 220
|
|
| L_ocin_972_ABC |
TIGR03608 |
putative bacteriocin export ABC transporter, lactococcin 972 group; A gene pair with a fairly ... |
4-210 |
2.75e-51 |
|
putative bacteriocin export ABC transporter, lactococcin 972 group; A gene pair with a fairly wide distribution consists of a polypeptide related to the lactococcin 972 (see TIGR01653) and multiple-membrane-spanning putative immunity protein (see TIGR01654). This model represents a small clade within the ABC transporters that regularly are found adjacent to these bacteriocin system gene pairs and are likely serve as export proteins. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Unknown substrate]
Pssm-ID: 188353 [Multi-domain] Cd Length: 206 Bit Score: 165.10 E-value: 2.75e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 4 MTNVYKEYpNGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLAERDVPYFRR-QLG 82
Cdd:TIGR03608 1 LKNISKKF-GDKVILDDLNLTIEKGKMYAIIGESGSGKSTLLNIIGLLEKFDSGQVYLNGQETPPLNSKKASKFRReKLG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 83 VIFQDFKLLPKLTVYENVSFALEVIEEEPDAIRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIVNRPKVVIAD 162
Cdd:TIGR03608 80 YLFQNFALIENETVEENLDLGLKYKKLSKKEKREKKKEALEKVGLNLKLKQKIYELSGGEQQRVALARAILKPPPLILAD 159
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 446516975 163 EPTGNLDIETALDIMNIFTRINERGTTIVMATHNADIVNtIRHRVIAI 210
Cdd:TIGR03608 160 EPTGSLDPKNRDEVLDLLLELNDEGKTIIIVTHDPEVAK-QADRVIEL 206
|
|
| FepC |
COG1120 |
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion ... |
1-218 |
6.66e-51 |
|
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion transport and metabolism, Coenzyme transport and metabolism];
Pssm-ID: 440737 [Multi-domain] Cd Length: 254 Bit Score: 165.60 E-value: 6.66e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 1 MIKMTNVYKEYPnGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLAERDVpyfRRQ 80
Cdd:COG1120 1 MLEAENLSVGYG-GRPVLDDVSLSLPPGEVTALLGPNGSGKSTLLRALAGLLKPSSGEVLLDGRDLASLSRREL---ARR 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 81 LGVIFQDFKLLPKLTVYENVSFA----LEVIEEEPDAIRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIVNRP 156
Cdd:COG1120 77 IAYVPQEPPAPFGLTVRELVALGryphLGLFGRPSAEDREAVEEALERTGLEHLADRPVDELSGGERQRVLIARALAQEP 156
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446516975 157 KVVIADEPTGNLDIETALDIMNIFTRIN-ERGTTIVMATHnaDIVNTIRH--RVIAIEGGKIVRD 218
Cdd:COG1120 157 PLLLLDEPTSHLDLAHQLEVLELLRRLArERGRTVVMVLH--DLNLAARYadRLVLLKDGRIVAQ 219
|
|
| ABC_MalK_N |
cd03301 |
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) ... |
2-216 |
3.91e-50 |
|
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) proteins function from bacteria to human, mediating the translocation of substances into and out of cells or organelles. ABC transporters contain two transmembrane-spanning domains (TMDs) or subunits and two nucleotide binding domains (NBDs) or subunits that couple transport to the hydrolysis of ATP. In the maltose transport system, the periplasmic maltose binding protein (MBP) stimulates the ATPase activity of the membrane-associated transporter, which consists of two transmembrane subunits, MalF and MalG, and two copies of the ATP binding subunit, MalK, and becomes tightly bound to the transporter in the catalytic transition state, ensuring that maltose is passed to the transporter as ATP is hydrolyzed.
Pssm-ID: 213268 [Multi-domain] Cd Length: 213 Bit Score: 162.42 E-value: 3.91e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 2 IKMTNVYKEYPNgMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIEtlaerDVPYFRRQL 81
Cdd:cd03301 1 VELENVTKRFGN-VTALDDLNLDIADGEFVVLLGPSGCGKTTTLRMIAGLEEPTSGRIYIGGRDVT-----DLPPKDRDI 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 82 GVIFQDFKLLPKLTVYENVSFALEVIEEEPDAIRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIVNRPKVVIA 161
Cdd:cd03301 75 AMVFQNYALYPHMTVYDNIAFGLKLRKVPKDEIDERVREVAELLQIEHLLDRKPKQLSGGQRQRVALGRAIVREPKVFLM 154
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 446516975 162 DEPTGNLDIETALDIMNIFTRINER-GTTIVMATHNADIVNTIRHRVIAIEGGKIV 216
Cdd:cd03301 155 DEPLSNLDAKLRVQMRAELKRLQQRlGTTTIYVTHDQVEAMTMADRIAVMNDGQIQ 210
|
|
| ABC_Mj1267_LivG_branched |
cd03219 |
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ... |
2-216 |
1.11e-49 |
|
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ABC transporter subfamily is involved in the transport of the hydrophobic amino acids leucine, isoleucine and valine. MJ1267 is a branched-chain amino acid transporter with 29% similarity to both the LivF and LivG components of the E. coli branched-chain amino acid transporter. MJ1267 contains an insertion from residues 114 to 123 characteristic of LivG (Leucine-Isoleucine-Valine) homologs. The branched-chain amino acid transporter from E. coli comprises a heterodimer of ABCs (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ).
Pssm-ID: 213186 [Multi-domain] Cd Length: 236 Bit Score: 161.84 E-value: 1.11e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 2 IKMTNVYKEYpNGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLAerdvPYFRRQL 81
Cdd:cd03219 1 LEVRGLTKRF-GGLVALDDVSFSVRPGEIHGLIGPNGAGKTTLFNLISGFLRPTSGSVLFDGEDITGLP----PHEIARL 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 82 GVI--FQDFKLLPKLTVYENV----------SFALEVIEEEPDAIRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIA 149
Cdd:cd03219 76 GIGrtFQIPRLFPELTVLENVmvaaqartgsGLLLARARREEREARERAEELLERVGLADLADRPAGELSYGQQRRLEIA 155
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446516975 150 RAIVNRPKVVIADEPTGNLDIETALDIMNIFTRINERGTTIVMATHNADIVNTIRHRVIAIEGGKIV 216
Cdd:cd03219 156 RALATDPKLLLLDEPAAGLNPEETEELAELIRELRERGITVLLVEHDMDVVMSLADRVTVLDQGRVI 222
|
|
| ABC_PstB_phosphate_transporter |
cd03260 |
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of ... |
2-216 |
2.18e-49 |
|
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of fundamental importance in the cell physiology of bacteria because phosphate is required as a nutrient. The Pst system of E. coli comprises four distinct subunits encoded by the pstS, pstA, pstB, and pstC genes. The PstS protein is a phosphate-binding protein located in the periplasmic space. PstA and PstC are hydrophobic and they form the transmembrane portion of the Pst system. PstB is the catalytic subunit, which couples the energy of ATP hydrolysis to the import of phosphate across cellular membranes through the Pst system, often referred as ABC-protein. PstB belongs to one of the largest superfamilies of proteins characterized by a highly conserved adenosine triphosphate (ATP) binding cassette (ABC), which is also a nucleotide binding domain (NBD).
Pssm-ID: 213227 [Multi-domain] Cd Length: 227 Bit Score: 161.19 E-value: 2.18e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 2 IKMTNVYKEYpNGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYR-----EEKPSTGSINVNGLTIETLAErDVPY 76
Cdd:cd03260 1 IELRDLNVYY-GDKHALKDISLDIPKGEITALIGPSGCGKSTLLRLLNRlndliPGAPDEGEVLLDGKDIYDLDV-DVLE 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 77 FRRQLGVIFQDFKLLPKlTVYENVSFALEVIEEEP-DAIRERVTEVLGLVGL----EDRADALpsELSGGEQQRVAIARA 151
Cdd:cd03260 79 LRRRVGMVFQKPNPFPG-SIYDNVAYGLRLHGIKLkEELDERVEEALRKAALwdevKDRLHAL--GLSGGQQQRLCLARA 155
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446516975 152 IVNRPKVVIADEPTGNLDIETALDIMNIFTRINERgTTIVMATHNADIVNTIRHRVIAIEGGKIV 216
Cdd:cd03260 156 LANEPEVLLLDEPTSALDPISTAKIEELIAELKKE-YTIVIVTHNMQQAARVADRTAFLLNGRLV 219
|
|
| ECF_ATPase_1 |
TIGR04520 |
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette ... |
2-218 |
5.13e-49 |
|
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the upstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 275313 [Multi-domain] Cd Length: 268 Bit Score: 161.44 E-value: 5.13e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 2 IKMTNVYKEYPNG-MKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGltIETLAERDVPYFRRQ 80
Cdd:TIGR04520 1 IEVENVSFSYPESeKPALKNVSLSIEKGEFVAIIGHNGSGKSTLAKLLNGLLLPTSGKVTVDG--LDTLDEENLWEIRKK 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 81 LGVIFQDfkllPK-----LTVYENVSFALEVIEEEPDAIRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIVNR 155
Cdd:TIGR04520 79 VGMVFQN----PDnqfvgATVEDDVAFGLENLGVPREEMRKRVDEALKLVGMEDFRDREPHLLSGGQKQRVAIAGVLAMR 154
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446516975 156 PKVVIADEPTGNLDIETALDIMNIFTRIN-ERGTTIVMATHNAD-IVNTirHRVIAIEGGKIVRD 218
Cdd:TIGR04520 155 PDIIILDEATSMLDPKGRKEVLETIRKLNkEEGITVISITHDMEeAVLA--DRVIVMNKGKIVAE 217
|
|
| GsiA |
COG1123 |
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ... |
1-218 |
1.18e-48 |
|
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440740 [Multi-domain] Cd Length: 514 Bit Score: 166.62 E-value: 1.18e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 1 MIKMTNVYKEYPNGMK-AIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPS---TGSINVNGLTIETLAERDvpy 76
Cdd:COG1123 4 LLEVRDLSVRYPGGDVpAVDGVSLTIAPGETVALVGESGSGKSTLALALMGLLPHGgriSGEVLLDGRDLLELSEAL--- 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 77 FRRQLGVIFQDFK--LLPkLTVYENVSFALEVIEEEPDAIRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIVN 154
Cdd:COG1123 81 RGRRIGMVFQDPMtqLNP-VTVGDQIAEALENLGLSRAEARARVLELLEAVGLERRLDRYPHQLSGGQRQRVAIAMALAL 159
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446516975 155 RPKVVIADEPTGNLDIETALDIMNIFTRIN-ERGTTIVMATHNADIVNTIRHRVIAIEGGKIVRD 218
Cdd:COG1123 160 DPDLLIADEPTTALDVTTQAEILDLLRELQrERGTTVLLITHDLGVVAEIADRVVVMDDGRIVED 224
|
|
| CysA |
COG1118 |
ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and ... |
6-216 |
2.32e-48 |
|
ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440735 [Multi-domain] Cd Length: 348 Bit Score: 161.85 E-value: 2.32e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 6 NVYKEYPNgMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETlaerDVPYFRRQLGVIF 85
Cdd:COG1118 7 NISKRFGS-FTLLDDVSLEIASGELVALLGPSGSGKTTLLRIIAGLETPDSGRIVLNGRDLFT----NLPPRERRVGFVF 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 86 QDFKLLPKLTVYENVSFALEVIEEEPDAIRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIVNRPKVVIADEPT 165
Cdd:COG1118 82 QHYALFPHMTVAENIAFGLRVRPPSKAEIRARVEELLELVQLEGLADRYPSQLSGGQRQRVALARALAVEPEVLLLDEPF 161
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 446516975 166 GNLDIETALDIMNIFTRI-NERGTTIVMATHN-------ADivntirhRVIAIEGGKIV 216
Cdd:COG1118 162 GALDAKVRKELRRWLRRLhDELGGTTVFVTHDqeealelAD-------RVVVMNQGRIE 213
|
|
| OpuBA |
COG1125 |
ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and ... |
1-216 |
3.44e-48 |
|
ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 440742 [Multi-domain] Cd Length: 306 Bit Score: 160.26 E-value: 3.44e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 1 MIKMTNVYKEYPNGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGltiETLAERDVPYFRRQ 80
Cdd:COG1125 1 MIEFENVTKRYPDGTVAVDDLSLTIPAGEFTVLVGPSGCGKTTTLRMINRLIEPTSGRILIDG---EDIRDLDPVELRRR 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 81 LG-VIfQDFKLLPKLTVYENVSFALEVIEEEPDAIRERVTEVLGLVGL--EDRADALPSELSGGEQQRVAIARAIVNRPK 157
Cdd:COG1125 78 IGyVI-QQIGLFPHMTVAENIATVPRLLGWDKERIRARVDELLELVGLdpEEYRDRYPHELSGGQQQRVGVARALAADPP 156
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446516975 158 VVIADEPTGNLDIETALDIMNIFTRINER-GTTIVMATHnaDIVNTIR--HRVIAIEGGKIV 216
Cdd:COG1125 157 ILLMDEPFGALDPITREQLQDELLRLQRElGKTIVFVTH--DIDEALKlgDRIAVMREGRIV 216
|
|
| SunT |
COG2274 |
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase ... |
2-218 |
3.61e-48 |
|
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms];
Pssm-ID: 441875 [Multi-domain] Cd Length: 711 Bit Score: 168.09 E-value: 3.61e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 2 IKMTNVYKEYP-NGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLaerDVPYFRRQ 80
Cdd:COG2274 474 IELENVSFRYPgDSPPVLDNISLTIKPGERVAIVGRSGSGKSTLLKLLLGLYEPTSGRILIDGIDLRQI---DPASLRRQ 550
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 81 LGVIFQDFKLLPKlTVYENVSFAlevieeEPDAIRERVTEVLGLVGLEDRADALP-----------SELSGGEQQRVAIA 149
Cdd:COG2274 551 IGVVLQDVFLFSG-TIRENITLG------DPDATDEEIIEAARLAGLHDFIEALPmgydtvvgeggSNLSGGQRQRLAIA 623
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446516975 150 RAIVNRPKVVIADEPTGNLDIETALDIMNIFTRINeRGTTIVMATHNADivnTIRH--RVIAIEGGKIVRD 218
Cdd:COG2274 624 RALLRNPRILILDEATSALDAETEAIILENLRRLL-KGRTVIIIAHRLS---TIRLadRIIVLDKGRIVED 690
|
|
| lolD |
PRK11629 |
lipoprotein-releasing ABC transporter ATP-binding protein LolD; |
1-196 |
1.17e-47 |
|
lipoprotein-releasing ABC transporter ATP-binding protein LolD;
Pssm-ID: 183244 [Multi-domain] Cd Length: 233 Bit Score: 156.90 E-value: 1.17e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 1 MIKMTNVYKEYPNG---MKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLAERDVPYF 77
Cdd:PRK11629 5 LLQCDNLCKRYQEGsvqTDVLHNVSFSIGEGEMMAIVGSSGSGKSTLLHLLGGLDTPTSGDVIFNGQPMSKLSSAAKAEL 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 78 R-RQLGVIFQDFKLLPKLTVYENVSFALEVIEEEPDAIRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIVNRP 156
Cdd:PRK11629 85 RnQKLGFIYQFHHLLPDFTALENVAMPLLIGKKKPAEINSRALEMLAAVGLEHRANHRPSELSGGERQRVAIARALVNNP 164
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 446516975 157 KVVIADEPTGNLDIETALDIMNIFTRINER-GTTIVMATHN 196
Cdd:PRK11629 165 RLVLADEPTGNLDARNADSIFQLLGELNRLqGTAFLVVTHD 205
|
|
| CydD |
COG4988 |
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease ... |
2-216 |
1.99e-47 |
|
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444012 [Multi-domain] Cd Length: 563 Bit Score: 164.16 E-value: 1.99e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 2 IKMTNVYKEYPNGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLAERDvpyFRRQL 81
Cdd:COG4988 337 IELEDVSFSYPGGRPALDGLSLTIPPGERVALVGPSGAGKSTLLNLLLGFLPPYSGSILINGVDLSDLDPAS---WRRQI 413
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 82 GVIFQDfKLLPKLTVYENVSFAlevieeEPDAIRERVTEVLGLVGLEDRADALP-----------SELSGGEQQRVAIAR 150
Cdd:COG4988 414 AWVPQN-PYLFAGTIRENLRLG------RPDASDEELEAALEAAGLDEFVAALPdgldtplgeggRGLSGGQAQRLALAR 486
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446516975 151 AIVNRPKVVIADEPTGNLDIETALDIMNIFTRINeRGTTIVMATHNADivnTIRH--RVIAIEGGKIV 216
Cdd:COG4988 487 ALLRDAPLLLLDEPTAHLDAETEAEILQALRRLA-KGRTVILITHRLA---LLAQadRILVLDDGRIV 550
|
|
| ABC_DR_subfamily_A |
cd03230 |
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily ... |
2-215 |
2.94e-47 |
|
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; This family of ATP-binding proteins belongs to a multi-subunit transporter involved in drug resistance (BcrA and DrrA), nodulation, lipid transport, and lantibiotic immunity. In bacteria and archaea, these transporters usually include an ATP-binding protein and one or two integral membrane proteins. Eukaryotic systems of the ABCA subfamily display ABC domains that are quite similar to this family. The ATP-binding domain shows the highest similarity between all members of the ABC transporter family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213197 [Multi-domain] Cd Length: 173 Bit Score: 153.71 E-value: 2.94e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 2 IKMTNVYKEYPNGmKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLAERdvpyFRRQL 81
Cdd:cd03230 1 IEVRNLSKRYGKK-TALDDISLTVEKGEIYGLLGPNGAGKTTLIKIILGLLKPDSGEIKVLGKDIKKEPEE----VKRRI 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 82 GVIFQDFKLLPKLTVYENVsfalevieeepdairervtevlglvgledradalpsELSGGEQQRVAIARAIVNRPKVVIA 161
Cdd:cd03230 76 GYLPEEPSLYENLTVRENL------------------------------------KLSGGMKQRLALAQALLHDPELLIL 119
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 446516975 162 DEPTGNLDIETALDIMNIFTRINERGTTIVMATHNADIVNTIRHRVIAIEGGKI 215
Cdd:cd03230 120 DEPTSGLDPESRREFWELLRELKKEGKTILLSSHILEEAERLCDRVAILNNGRI 173
|
|
| ABC_tran |
pfam00005 |
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ... |
20-165 |
5.07e-47 |
|
ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.
Pssm-ID: 394964 [Multi-domain] Cd Length: 150 Bit Score: 152.42 E-value: 5.07e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 20 GLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGltiETLAERDVPYFRRQLGVIFQDFKLLPKLTVYEN 99
Cdd:pfam00005 3 NVSLTLNPGEILALVGPNGAGKSTLLKLIAGLLSPTEGTILLDG---QDLTDDERKSLRKEIGYVFQDPQLFPRLTVREN 79
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 100 VSFALEVIEEEPDAIRERVTEVLGLVGLED----RADALPSELSGGEQQRVAIARAIVNRPKVVIADEPT 165
Cdd:pfam00005 80 LRLGLLLKGLSKREKDARAEEALEKLGLGDladrPVGERPGTLSGGQRQRVAIARALLTKPKLLLLDEPT 149
|
|
| PRK10535 |
PRK10535 |
macrolide ABC transporter ATP-binding protein/permease MacB; |
1-218 |
7.31e-47 |
|
macrolide ABC transporter ATP-binding protein/permease MacB;
Pssm-ID: 182528 [Multi-domain] Cd Length: 648 Bit Score: 163.74 E-value: 7.31e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 1 MIKMTNVYKEYPNG---MKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLAERDVPYF 77
Cdd:PRK10535 4 LLELKDIRRSYPSGeeqVEVLKGISLDIYAGEMVAIVGASGSGKSTLMNILGCLDKPTSGTYRVAGQDVATLDADALAQL 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 78 RRQ-LGVIFQDFKLLPKLTVYENVSFALEVIEEEPDAIRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIVNRP 156
Cdd:PRK10535 84 RREhFGFIFQRYHLLSHLTAAQNVEVPAVYAGLERKQRLLRAQELLQRLGLEDRVEYQPSQLSGGQQQRVSIARALMNGG 163
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446516975 157 KVVIADEPTGNLDIETALDIMNIFTRINERGTTIVMATHNADIVNTIRhRVIAIEGGKIVRD 218
Cdd:PRK10535 164 QVILADEPTGALDSHSGEEVMAILHQLRDRGHTVIIVTHDPQVAAQAE-RVIEIRDGEIVRN 224
|
|
| CydC |
COG4987 |
ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease ... |
2-216 |
1.04e-46 |
|
ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444011 [Multi-domain] Cd Length: 569 Bit Score: 162.24 E-value: 1.04e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 2 IKMTNVYKEYPNGMK-AIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLAERDVpyfRRQ 80
Cdd:COG4987 334 LELEDVSFRYPGAGRpVLDGLSLTLPPGERVAIVGPSGSGKSTLLALLLRFLDPQSGSITLGGVDLRDLDEDDL---RRR 410
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 81 LGVIFQDfkllPKL---TVYENVSFALevieeePDAIRERVTEVLGLVGLEDRADALP-----------SELSGGEQQRV 146
Cdd:COG4987 411 IAVVPQR----PHLfdtTLRENLRLAR------PDATDEELWAALERVGLGDWLAALPdgldtwlgeggRRLSGGERRRL 480
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446516975 147 AIARAIVNRPKVVIADEPTGNLDIETALDIMN-IFTRINERgtTIVMATHNADIVNTIrHRVIAIEGGKIV 216
Cdd:COG4987 481 ALARALLRDAPILLLDEPTEGLDAATEQALLAdLLEALAGR--TVLLITHRLAGLERM-DRILVLEDGRIV 548
|
|
| ABC_CysA_sulfate_importer |
cd03296 |
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex ... |
2-215 |
1.31e-46 |
|
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex cysAWTP involved in sulfate import. Responsible for energy coupling to the transport system. The complex is composed of two ATP-binding proteins (cysA), two transmembrane proteins (cysT and cysW), and a solute-binding protein (cysP). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213263 [Multi-domain] Cd Length: 239 Bit Score: 154.42 E-value: 1.31e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 2 IKMTNVYKEYPNgMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLAERDvpyfrRQL 81
Cdd:cd03296 3 IEVRNVSKRFGD-FVALDDVSLDIPSGELVALLGPSGSGKTTLLRLIAGLERPDSGTILFGGEDATDVPVQE-----RNV 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 82 GVIFQDFKLLPKLTVYENVSFALEV--IEEEPDA--IRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIVNRPK 157
Cdd:cd03296 77 GFVFQHYALFRHMTVFDNVAFGLRVkpRSERPPEaeIRAKVHELLKLVQLDWLADRYPAQLSGGQRQRVALARALAVEPK 156
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 446516975 158 VVIADEPTGNLDIETALDIMNIFTRINER-GTTIVMATHNADIVNTIRHRVIAIEGGKI 215
Cdd:cd03296 157 VLLLDEPFGALDAKVRKELRRWLRRLHDElHVTTVFVTHDQEEALEVADRVVVMNKGRI 215
|
|
| FetA |
COG4619 |
ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism]; |
18-215 |
5.73e-46 |
|
ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443661 [Multi-domain] Cd Length: 209 Bit Score: 151.51 E-value: 5.73e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 18 IAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLaerDVPYFRRQLGVIFQDFKLLPKlTVY 97
Cdd:COG4619 16 LSPVSLTLEAGECVAITGPSGSGKSTLLRALADLDPPTSGEIYLDGKPLSAM---PPPEWRRQVAYVPQEPALWGG-TVR 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 98 ENVSFALEVIEEEPDaiRERVTEVLGLVGLEDRA-DALPSELSGGEQQRVAIARAIVNRPKVVIADEPTGNLDIETALDI 176
Cdd:COG4619 92 DNLPFPFQLRERKFD--RERALELLERLGLPPDIlDKPVERLSGGERQRLALIRALLLQPDVLLLDEPTSALDPENTRRV 169
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 446516975 177 MNIFTR-INERGTTIVMATHNADIVNTIRHRVIAIEGGKI 215
Cdd:COG4619 170 EELLREyLAEEGRAVLWVSHDPEQIERVADRVLTLEAGRL 209
|
|
| PRK11264 |
PRK11264 |
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional |
1-216 |
1.89e-45 |
|
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional
Pssm-ID: 183063 [Multi-domain] Cd Length: 250 Bit Score: 151.83 E-value: 1.89e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 1 MIKMTNVYKEYpNGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETL-----AERDVP 75
Cdd:PRK11264 3 AIEVKNLVKKF-HGQTVLHGIDLEVKPGEVVAIIGPSGSGKTTLLRCINLLEQPEAGTIRVGDITIDTArslsqQKGLIR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 76 YFRRQLGVIFQDFKLLPKLTVYENVSFALEVIEEEP-DAIRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIVN 154
Cdd:PRK11264 82 QLRQHVGFVFQNFNLFPHRTVLENIIEGPVIVKGEPkEEATARARELLAKVGLAGKETSYPRRLSGGQQQRVAIARALAM 161
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446516975 155 RPKVVIADEPTGNLDIETALDIMNIFTRINERGTTIVMATHNADIVNTIRHRVIAIEGGKIV 216
Cdd:PRK11264 162 RPEVILFDEPTSALDPELVGEVLNTIRQLAQEKRTMVIVTHEMSFARDVADRAIFMDQGRIV 223
|
|
| ABC_Pro_Gly_Betaine |
cd03294 |
ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This ... |
25-216 |
2.41e-45 |
|
ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This family comprises the glycine betaine/L-proline ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporters is the obligatory coupling of ATP hydrolysis to substrate translocation. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213261 [Multi-domain] Cd Length: 269 Bit Score: 152.03 E-value: 2.41e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 25 IKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLAERDVPYFRRQ-LGVIFQDFKLLPKLTVYENVSFA 103
Cdd:cd03294 47 VREGEIFVIMGLSGSGKSTLLRCINRLIEPTSGKVLIDGQDIAAMSRKELRELRRKkISMVFQSFALLPHRTVLENVAFG 126
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 104 LEVIEEEPDAIRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIVNRPKVVIADEPTGNLDIETALDIMNIFTRI 183
Cdd:cd03294 127 LEVQGVPRAEREERAAEALELVGLEGWEHKYPDELSGGMQQRVGLARALAVDPDILLMDEAFSALDPLIRREMQDELLRL 206
|
170 180 190
....*....|....*....|....*....|....
gi 446516975 184 N-ERGTTIVMATHNADIVNTIRHRVIAIEGGKIV 216
Cdd:cd03294 207 QaELQKTIVFITHDLDEALRLGDRIAIMKDGRLV 240
|
|
| potA |
PRK09452 |
spermidine/putrescine ABC transporter ATP-binding protein PotA; |
2-218 |
3.05e-45 |
|
spermidine/putrescine ABC transporter ATP-binding protein PotA;
Pssm-ID: 236523 [Multi-domain] Cd Length: 375 Bit Score: 154.72 E-value: 3.05e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 2 IKMTNVYKEYpNGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIEtlaerDVPYFRRQL 81
Cdd:PRK09452 15 VELRGISKSF-DGKEVISNLDLTINNGEFLTLLGPSGCGKTTVLRLIAGFETPDSGRIMLDGQDIT-----HVPAENRHV 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 82 GVIFQDFKLLPKLTVYENVSFALEVIEEEPDAIRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIVNRPKVVIA 161
Cdd:PRK09452 89 NTVFQSYALFPHMTVFENVAFGLRMQKTPAAEITPRVMEALRMVQLEEFAQRKPHQLSGGQQQRVAIARAVVNKPKVLLL 168
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 446516975 162 DEPTGNLDIETALDIMNIFTRIN-ERGTTIVMATHNADIVNTIRHRVIAIEGGKIVRD 218
Cdd:PRK09452 169 DESLSALDYKLRKQMQNELKALQrKLGITFVFVTHDQEEALTMSDRIVVMRDGRIEQD 226
|
|
| potA |
TIGR01187 |
spermidine/putrescine ABC transporter ATP-binding subunit; This model describes spermidine ... |
33-218 |
9.95e-45 |
|
spermidine/putrescine ABC transporter ATP-binding subunit; This model describes spermidine/putrescine ABC transporter, ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. Polyamines like spermidine and putrescine play vital role in cell proliferation, differentiation, and ion homeostasis. The concentration of polyamines within the cell are regulated by biosynthesis, degradation and transport (uptake and efflux included). [Transport and binding proteins, Amino acids, peptides and amines]
Pssm-ID: 162242 [Multi-domain] Cd Length: 325 Bit Score: 151.88 E-value: 9.95e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 33 VVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIEtlaerDVPYFRRQLGVIFQDFKLLPKLTVYENVSFALEVIEEEPD 112
Cdd:TIGR01187 1 LLGPSGCGKTTLLRLLAGFEQPDSGSIMLDGEDVT-----NVPPHLRHINMVFQSYALFPHMTVEENVAFGLKMRKVPRA 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 113 AIRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIVNRPKVVIADEPTGNLDIETALDIMNIFTRINER-GTTIV 191
Cdd:TIGR01187 76 EIKPRVLEALRLVQLEEFADRKPHQLSGGQQQRVALARALVFKPKILLLDEPLSALDKKLRDQMQLELKTIQEQlGITFV 155
|
170 180
....*....|....*....|....*..
gi 446516975 192 MATHNADIVNTIRHRVIAIEGGKIVRD 218
Cdd:TIGR01187 156 FVTHDQEEAMTMSDRIAIMRKGKIAQI 182
|
|
| ArtP |
COG4161 |
ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism]; |
2-216 |
1.06e-44 |
|
ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443326 [Multi-domain] Cd Length: 242 Bit Score: 149.39 E-value: 1.06e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 2 IKMTNVYKEYpNGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTI---ETLAERDVPYFR 78
Cdd:COG4161 3 IQLKNINCFY-GSHQALFDINLECPSGETLVLLGPSGAGKSSLLRVLNLLETPDSGQLNIAGHQFdfsQKPSEKAIRLLR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 79 RQLGVIFQDFKLLPKLTVYENVSFA-LEVIEEEPDAIRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIVNRPK 157
Cdd:COG4161 82 QKVGMVFQQYNLWPHLTVMENLIEApCKVLGLSKEQAREKAMKLLARLRLTDKADRFPLHLSGGQQQRVAIARALMMEPQ 161
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 446516975 158 VVIADEPTGNLDIETALDIMNIFTRINERGTTIVMATHNADIVNTIRHRVIAIEGGKIV 216
Cdd:COG4161 162 VLLFDEPTAALDPEITAQVVEIIRELSQTGITQVIVTHEVEFARKVASQVVYMEKGRII 220
|
|
| ZnuC |
COG1121 |
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism]; ... |
1-215 |
2.52e-44 |
|
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440738 [Multi-domain] Cd Length: 245 Bit Score: 148.70 E-value: 2.52e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 1 MIKMTNVYKEYpNGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLAERD--VPyfr 78
Cdd:COG1121 6 AIELENLTVSY-GGRPVLEDVSLTIPPGEFVAIVGPNGAGKSTLLKAILGLLPPTSGTVRLFGKPPRRARRRIgyVP--- 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 79 rQLGVIFQDFkllPkLTVYENVS---------FALEVIEEepdaiRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIA 149
Cdd:COG1121 82 -QRAEVDWDF---P-ITVRDVVLmgrygrrglFRRPSRAD-----REAVDEALERVGLEDLADRPIGELSGGQQQRVLLA 151
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446516975 150 RAIVNRPKVVIADEPTGNLDIETALDIMNIFTRINERGTTIVMATHNADIVNTIRHRVIAIEGGKI 215
Cdd:COG1121 152 RALAQDPDLLLLDEPFAGVDAATEEALYELLRELRREGKTILVVTHDLGAVREYFDRVLLLNRGLV 217
|
|
| artP |
PRK11124 |
arginine transporter ATP-binding subunit; Provisional |
2-216 |
3.39e-44 |
|
arginine transporter ATP-binding subunit; Provisional
Pssm-ID: 182980 [Multi-domain] Cd Length: 242 Bit Score: 148.24 E-value: 3.39e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 2 IKMTNVYKEYPNGmKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTI---ETLAERDVPYFR 78
Cdd:PRK11124 3 IQLNGINCFYGAH-QALFDITLDCPQGETLVLLGPSGAGKSSLLRVLNLLEMPRSGTLNIAGNHFdfsKTPSDKAIRELR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 79 RQLGVIFQDFKLLPKLTVYENVSFA----LEVIEEEPdaiRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIVN 154
Cdd:PRK11124 82 RNVGMVFQQYNLWPHLTVQQNLIEApcrvLGLSKDQA---LARAEKLLERLRLKPYADRFPLHLSGGQQQRVAIARALMM 158
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446516975 155 RPKVVIADEPTGNLDIETALDIMNIFTRINERGTTIVMATHNADIVNTIRHRVIAIEGGKIV 216
Cdd:PRK11124 159 EPQVLLFDEPTAALDPEITAQIVSIIRELAETGITQVIVTHEVEVARKTASRVVYMENGHIV 220
|
|
| PhnT2 |
TIGR03265 |
putative 2-aminoethylphosphonate ABC transporter, ATP-binding protein; This ABC transporter ... |
2-216 |
4.29e-44 |
|
putative 2-aminoethylphosphonate ABC transporter, ATP-binding protein; This ABC transporter ATP-binding protein is found in a number of genomes in operon-like contexts strongly suggesting a substrate specificity for 2-aminoethylphosphonate (2-AEP). The characterized PhnSTUV system is absent in the genomes in which this system is found. These genomes encode systems for the catabolism of 2-AEP, making the need for a 2-AEP-specific transporter likely. [Transport and binding proteins, Amino acids, peptides and amines]
Pssm-ID: 274496 [Multi-domain] Cd Length: 353 Bit Score: 150.96 E-value: 4.29e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 2 IKMTNVYKEYpNGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLaerdvPYFRRQL 81
Cdd:TIGR03265 5 LSIDNIRKRF-GAFTALKDISLSVKKGEFVCLLGPSGCGKTTLLRIIAGLERQTAGTIYQGGRDITRL-----PPQKRDY 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 82 GVIFQDFKLLPKLTVYENVSFALEVIEEEPDAIRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIVNRPKVVIA 161
Cdd:TIGR03265 79 GIVFQSYALFPNLTVADNIAYGLKNRGMGRAEVAERVAELLDLVGLPGSERKYPGQLSGGQQQRVALARALATSPGLLLL 158
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 446516975 162 DEPTGNLDIETALDIMNIFTRINER-GTTIVMATHNADIVNTIRHRVIAIEGGKIV 216
Cdd:TIGR03265 159 DEPLSALDARVREHLRTEIRQLQRRlGVTTIMVTHDQEEALSMADRIVVMNHGVIE 214
|
|
| ABCC_MRP_Like |
cd03228 |
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP ... |
2-214 |
4.67e-44 |
|
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP (Multidrug Resistance Protein)-like transporters are involved in drug, peptide, and lipid export. They belong to the subfamily C of the ATP-binding cassette (ABC) superfamily of transport proteins. The ABCC subfamily contains transporters with a diverse functional spectrum that includes ion transport, cell surface receptor, and toxin secretion activities. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains, each composed of six transmembrane (TM) helices, and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213195 [Multi-domain] Cd Length: 171 Bit Score: 145.60 E-value: 4.67e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 2 IKMTNVYKEYPNGMK-AIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLAERDVpyfRRQ 80
Cdd:cd03228 1 IEFKNVSFSYPGRPKpVLKDVSLTIKPGEKVAIVGPSGSGKSTLLKLLLRLYDPTSGEILIDGVDLRDLDLESL---RKN 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 81 LGVIFQDFKLLPKlTVYENVsfalevieeepdairervtevlglvgledradalpseLSGGEQQRVAIARAIVNRPKVVI 160
Cdd:cd03228 78 IAYVPQDPFLFSG-TIRENI-------------------------------------LSGGQRQRIAIARALLRDPPILI 119
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 446516975 161 ADEPTGNLDIETALDIMNIFTRInERGTTIVMATHNadiVNTIRH--RVIAIEGGK 214
Cdd:cd03228 120 LDEATSALDPETEALILEALRAL-AKGKTVIVIAHR---LSTIRDadRIIVLDDGR 171
|
|
| ABC_Iron-Siderophores_B12_Hemin |
cd03214 |
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related ... |
3-218 |
4.79e-44 |
|
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; ABC transporters, involved in the uptake of siderophores, heme, and vitamin B12, are widely conserved in bacteria and archaea. Only very few species lack representatives of the siderophore family transporters. The E. coli BtuCD protein is an ABC transporter mediating vitamin B12 uptake. The two ATP-binding cassettes (BtuD) are in close contact with each other, as are the two membrane-spanning subunits (BtuC); this arrangement is distinct from that observed for the E. coli lipid flippase MsbA. The BtuC subunits provide 20 transmembrane helices grouped around a translocation pathway that is closed to the cytoplasm by a gate region, whereas the dimer arrangement of the BtuD subunits resembles the ATP-bound form of the Rad50 DNA repair enzyme. A prominent cytoplasmic loop of BtuC forms the contact region with the ATP-binding cassette and represent a conserved motif among the ABC transporters.
Pssm-ID: 213181 [Multi-domain] Cd Length: 180 Bit Score: 145.66 E-value: 4.79e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 3 KMTNVYKEYPNGmKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLAERDvpyFRRQLG 82
Cdd:cd03214 1 EVENLSVGYGGR-TVLDDLSLSIEAGEIVGILGPNGAGKSTLLKTLAGLLKPSSGEILLDGKDLASLSPKE---LARKIA 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 83 VIFQdfkllpkltvyenvsfALEvieeepdairervtevlgLVGLEDRADALPSELSGGEQQRVAIARAIVNRPKVVIAD 162
Cdd:cd03214 77 YVPQ----------------ALE------------------LLGLAHLADRPFNELSGGERQRVLLARALAQEPPILLLD 122
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 446516975 163 EPTGNLDIETALDIMNIFTRIN-ERGTTIVMATHNADIVNTIRHRVIAIEGGKIVRD 218
Cdd:cd03214 123 EPTSHLDIAHQIELLELLRRLArERGKTVVMVLHDLNLAARYADRVILLKDGRIVAQ 179
|
|
| DppD |
COG0444 |
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ... |
1-216 |
7.54e-44 |
|
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];
Pssm-ID: 440213 [Multi-domain] Cd Length: 320 Bit Score: 149.43 E-value: 7.54e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 1 MIKMTNVYKEYP--NGM-KAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKP---STGSINVNGLTIETLAERDV 74
Cdd:COG0444 1 LLEVRNLKVYFPtrRGVvKAVDGVSFDVRRGETLGLVGESGSGKSTLARAILGLLPPpgiTSGEILFDGEDLLKLSEKEL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 75 PYFR-RQLGVIFQD-FKLL-PKLTVYENVSFALEVIEEEP-DAIRERVTEVLGLVGL---EDRADALPSELSGGEQQRVA 147
Cdd:COG0444 81 RKIRgREIQMIFQDpMTSLnPVMTVGDQIAEPLRIHGGLSkAEARERAIELLERVGLpdpERRLDRYPHELSGGMRQRVM 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446516975 148 IARAIVNRPKVVIADEPTgnldieTALD------IMNIFTRIN-ERGTTIVMATHNADIVNTIRHRVIAIEGGKIV 216
Cdd:COG0444 161 IARALALEPKLLIADEPT------TALDvtiqaqILNLLKDLQrELGLAILFITHDLGVVAEIADRVAVMYAGRIV 230
|
|
| ThiQ |
COG3840 |
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism]; |
1-216 |
9.24e-44 |
|
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];
Pssm-ID: 443051 [Multi-domain] Cd Length: 232 Bit Score: 146.82 E-value: 9.24e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 1 MIKMTNVYKEYPN-GMKAiaglTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLAerdvPYfRR 79
Cdd:COG3840 1 MLRLDDLTYRYGDfPLRF----DLTIAAGERVAILGPSGAGKSTLLNLIAGFLPPDSGRILWNGQDLTALP----PA-ER 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 80 QLGVIFQDFKLLPKLTVYENVSFALEvieeePD-----AIRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIV- 153
Cdd:COG3840 72 PVSMLFQENNLFPHLTVAQNIGLGLR-----PGlkltaEQRAQVEQALERVGLAGLLDRLPGQLSGGQRQRVALARCLVr 146
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446516975 154 NRPkVVIADEPTGNLDIetAL--DIMNIFTRIN-ERGTTIVMATHNADIVNTIRHRVIAIEGGKIV 216
Cdd:COG3840 147 KRP-ILLLDEPFSALDP--ALrqEMLDLVDELCrERGLTVLMVTHDPEDAARIADRVLLVADGRIA 209
|
|
| ABC_ModC_molybdenum_transporter |
cd03297 |
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type ... |
16-216 |
1.49e-43 |
|
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213264 [Multi-domain] Cd Length: 214 Bit Score: 145.52 E-value: 1.49e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 16 KAIAGLTVNIK---QGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTI-ETLAERDVPYFRRQLGVIFQDFKLL 91
Cdd:cd03297 8 KRLPDFTLKIDfdlNEEVTGIFGASGAGKSTLLRCIAGLEKPDGGTIVLNGTVLfDSRKKINLPPQQRKIGLVFQQYALF 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 92 PKLTVYENVSFALEVIEEEPDaiRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIVNRPKVVIADEPTGNLDIE 171
Cdd:cd03297 88 PHLNVRENLAFGLKRKRNRED--RISVDELLDLLGLDHLLNRYPAQLSGGEKQRVALARALAAQPELLLLDEPFSALDRA 165
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 446516975 172 TALDIMNIFTRINER-GTTIVMATHNADIVNTIRHRVIAIEGGKIV 216
Cdd:cd03297 166 LRLQLLPELKQIKKNlNIPVIFVTHDLSEAEYLADRIVVMEDGRLQ 211
|
|
| ABC_ATPase |
cd00267 |
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large ... |
3-214 |
2.74e-43 |
|
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213179 [Multi-domain] Cd Length: 157 Bit Score: 143.15 E-value: 2.74e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 3 KMTNVYKEYPNGmKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGltiETLAERDVPYFRRQLG 82
Cdd:cd00267 1 EIENLSFRYGGR-TALDNVSLTLKAGEIVALVGPNGSGKSTLLRAIAGLLKPTSGEILIDG---KDIAKLPLEELRRRIG 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 83 VIFQdfkllpkltvyenvsfalevieeepdairervtevlglvgledradalpseLSGGEQQRVAIARAIVNRPKVVIAD 162
Cdd:cd00267 77 YVPQ---------------------------------------------------LSGGQRQRVALARALLLNPDLLLLD 105
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 446516975 163 EPTGNLDIETALDIMNIFTRINERGTTIVMATHNADIVNTIRHRVIAIEGGK 214
Cdd:cd00267 106 EPTSGLDPASRERLLELLRELAEEGRTVIIVTHDPELAELAADRVIVLKDGK 157
|
|
| CcmA |
COG4133 |
ABC-type transport system involved in cytochrome c biogenesis, ATPase component ... |
1-214 |
1.41e-42 |
|
ABC-type transport system involved in cytochrome c biogenesis, ATPase component [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 443308 [Multi-domain] Cd Length: 206 Bit Score: 143.00 E-value: 1.41e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 1 MIKMTNVYKEYpNGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLAERdvpyFRRQ 80
Cdd:COG4133 2 MLEAENLSCRR-GERLLFSGLSFTLAAGEALALTGPNGSGKTTLLRILAGLLPPSAGEVLWNGEPIRDARED----YRRR 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 81 LGVIFQDFKLLPKLTVYENVSFALEVIEEEPDaiRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIVNRPKVVI 160
Cdd:COG4133 77 LAYLGHADGLKPELTVRENLRFWAALYGLRAD--REAIDEALEAVGLAGLADLPVRQLSAGQKRRVALARLLLSPAPLWL 154
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 446516975 161 ADEPTGNLDIETALDIMNIFTRINERGTTIVMATHnaDIVNTIRHRVIAIEGGK 214
Cdd:COG4133 155 LDEPFTALDAAGVALLAELIAAHLARGGAVLLTTH--QPLELAAARVLDLGDFK 206
|
|
| cbiO |
TIGR01166 |
cobalt transport protein ATP-binding subunit; This model describes the ATP binding subunit of ... |
11-199 |
2.81e-42 |
|
cobalt transport protein ATP-binding subunit; This model describes the ATP binding subunit of the multisubunit cobalt transporter in bacteria and its equivalents in archaea. The model is restricted to ATP subunit that is a part of the cobalt transporter, which belongs to the ABC transporter superfamily (ATP Binding Cassette). The model excludes ATP binding subunit that are associated with other transporters belonging to ABC transporter superfamily. This superfamily includes two groups, one which catalyze the uptake of small molecules, including ions from the external milieu and the other group which is engaged in the efflux of small molecular weight compounds and ions from within the cell. Energy derived from the hydrolysis of ATP drive the both the process of uptake and efflux. [Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 130234 [Multi-domain] Cd Length: 190 Bit Score: 141.79 E-value: 2.81e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 11 YPNGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIEtLAERDVPYFRRQLGVIFQDF-K 89
Cdd:TIGR01166 1 YPGGPEVLKGLNFAAERGEVLALLGANGAGKSTLLLHLNGLLRPQSGAVLIDGEPLD-YSRKGLLERRQRVGLVFQDPdD 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 90 LLPKLTVYENVSFALEVIEEEPDAIRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIVNRPKVVIADEPTGNLD 169
Cdd:TIGR01166 80 QLFAADVDQDVAFGPLNLGLSEAEVERRVREALTAVGASGLRERPTHCLSGGEKKRVAIAGAVAMRPDVLLLDEPTAGLD 159
|
170 180 190
....*....|....*....|....*....|
gi 446516975 170 IETALDIMNIFTRINERGTTIVMATHNADI 199
Cdd:TIGR01166 160 PAGREQMLAILRRLRAEGMTVVISTHDVDL 189
|
|
| MdlB |
COG1132 |
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms]; |
11-216 |
3.18e-42 |
|
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];
Pssm-ID: 440747 [Multi-domain] Cd Length: 579 Bit Score: 150.32 E-value: 3.18e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 11 YPNGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLAERDVpyfRRQLGVIFQDFKL 90
Cdd:COG1132 349 YPGDRPVLKDISLTIPPGETVALVGPSGSGKSTLVNLLLRFYDPTSGRILIDGVDIRDLTLESL---RRQIGVVPQDTFL 425
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 91 LpKLTVYENVSFAlevieeEPDAIRERVTEVLGLVGLEDRADALP-----------SELSGGEQQRVAIARAIVNRPKVV 159
Cdd:COG1132 426 F-SGTIRENIRYG------RPDATDEEVEEAAKAAQAHEFIEALPdgydtvvgergVNLSGGQRQRIAIARALLKDPPIL 498
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 446516975 160 IADEPTGNLDIETALDIMNIFTRINERGTTIVMAtHNadiVNTIRH--RVIAIEGGKIV 216
Cdd:COG1132 499 ILDEATSALDTETEALIQEALERLMKGRTTIVIA-HR---LSTIRNadRILVLDDGRIV 553
|
|
| LivG |
COG0411 |
ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid ... |
14-216 |
5.85e-42 |
|
ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid transport and metabolism];
Pssm-ID: 440180 [Multi-domain] Cd Length: 257 Bit Score: 142.87 E-value: 5.85e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 14 GMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLAerdvPYFRRQLGVI--FQDFKLL 91
Cdd:COG0411 16 GLVAVDDVSLEVERGEIVGLIGPNGAGKTTLFNLITGFYRPTSGRILFDGRDITGLP----PHRIARLGIArtFQNPRLF 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 92 PKLTVYENV---------------SFALEVIEEEPDAIRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIVNRP 156
Cdd:COG0411 92 PELTVLENVlvaaharlgrgllaaLLRLPRARREEREARERAEELLERVGLADRADEPAGNLSYGQQRRLEIARALATEP 171
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446516975 157 KVVIADEPTGNLDIETALDIMNIFTRIN-ERGTTIVMATHNADIVNTIRHRVIAIEGGKIV 216
Cdd:COG0411 172 KLLLLDEPAAGLNPEETEELAELIRRLRdERGITILLIEHDMDLVMGLADRIVVLDFGRVI 232
|
|
| ABC_Metallic_Cations |
cd03235 |
ATP-binding cassette domain of the metal-type transporters; This family includes transporters ... |
13-215 |
8.99e-42 |
|
ATP-binding cassette domain of the metal-type transporters; This family includes transporters involved in the uptake of various metallic cations such as iron, manganese, and zinc. The ATPases of this group of transporters are very similar to members of iron-siderophore uptake family suggesting that they share a common ancestor. The best characterized metal-type ABC transporters are the YfeABCD system of Y. pestis, the SitABCD system of Salmonella enterica serovar Typhimurium, and the SitABCD transporter of Shigella flexneri. Moreover other uncharacterized homologs of these metal-type transporters are mainly found in pathogens like Haemophilus or enteroinvasive E. coli isolates.
Pssm-ID: 213202 [Multi-domain] Cd Length: 213 Bit Score: 141.13 E-value: 8.99e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 13 NGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLAERD--VPyfrrQLGVIFQDFkl 90
Cdd:cd03235 10 GGHPVLEDVSFEVKPGEFLAIVGPNGAGKSTLLKAILGLLKPTSGSIRVFGKPLEKERKRIgyVP----QRRSIDRDF-- 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 91 lPkLTVYENVSFAL----EVIEEEPDAIRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIVNRPKVVIADEPTG 166
Cdd:cd03235 84 -P-ISVRDVVLMGLyghkGLFRRLSKADKAKVDEALERVGLSELADRQIGELSGGQQQRVLLARALVQDPDLLLLDEPFA 161
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 446516975 167 NLDIETALDIMNIFTRINERGTTIVMATHNADIVNTIRHRVIAIEGGKI 215
Cdd:cd03235 162 GVDPKTQEDIYELLRELRREGMTILVVTHDLGLVLEYFDRVLLLNRTVV 210
|
|
| potG |
PRK11607 |
putrescine ABC transporter ATP-binding subunit PotG; |
1-217 |
1.11e-41 |
|
putrescine ABC transporter ATP-binding subunit PotG;
Pssm-ID: 183226 [Multi-domain] Cd Length: 377 Bit Score: 145.36 E-value: 1.11e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 1 MIKMTNVYKEYpNGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIEtlaerDVPYFRRQ 80
Cdd:PRK11607 19 LLEIRNLTKSF-DGQHAVDDVSLTIYKGEIFALLGASGCGKSTLLRMLAGFEQPTAGQIMLDGVDLS-----HVPPYQRP 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 81 LGVIFQDFKLLPKLTVYENVSFALEVIEEEPDAIRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIVNRPKVVI 160
Cdd:PRK11607 93 INMMFQSYALFPHMTVEQNIAFGLKQDKLPKAEIASRVNEMLGLVHMQEFAKRKPHQLSGGQRQRVALARSLAKRPKLLL 172
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446516975 161 ADEPTGNLDIE----TALDIMNIFTRInerGTTIVMATHNADIVNTIRHRVIAIEGGKIVR 217
Cdd:PRK11607 173 LDEPMGALDKKlrdrMQLEVVDILERV---GVTCVMVTHDQEEAMTMAGRIAIMNRGKFVQ 230
|
|
| ABC_ModC_like |
cd03299 |
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely ... |
25-216 |
1.83e-41 |
|
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely related to ModC. ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213266 [Multi-domain] Cd Length: 235 Bit Score: 140.93 E-value: 1.83e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 25 IKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLaerdvPYFRRQLGVIFQDFKLLPKLTVYENVSFAL 104
Cdd:cd03299 22 VERGDYFVILGPTGSGKSVLLETIAGFIKPDSGKILLNGKDITNL-----PPEKRDISYVPQNYALFPHMTVYKNIAYGL 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 105 EVIEEEPDAIRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIVNRPKVVIADEPTGNLDIETALDIMNIFTRI- 183
Cdd:cd03299 97 KKRKVDKKEIERKVLEIAEMLGIDHLLNRKPETLSGGEQQRVAIARALVVNPKILLLDEPFSALDVRTKEKLREELKKIr 176
|
170 180 190
....*....|....*....|....*....|...
gi 446516975 184 NERGTTIVMATHNADIVNTIRHRVIAIEGGKIV 216
Cdd:cd03299 177 KEFGVTVLHVTHDFEEAWALADKVAIMLNGKLI 209
|
|
| TauB |
COG4525 |
ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism]; |
1-169 |
1.06e-40 |
|
ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443596 [Multi-domain] Cd Length: 262 Bit Score: 139.61 E-value: 1.06e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 1 MIKMTNVYKEYPNGMK---AIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETL-AERdvpy 76
Cdd:COG4525 3 MLTVRHVSVRYPGGGQpqpALQDVSLTIESGEFVVALGASGCGKTTLLNLIAGFLAPSSGEITLDGVPVTGPgADR---- 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 77 frrqlGVIFQDFKLLPKLTVYENVSFALEVIEEEPDAIRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIVNRP 156
Cdd:COG4525 79 -----GVVFQKDALLPWLNVLDNVAFGLRLRGVPKAERRARAEELLALVGLADFARRRIWQLSGGMRQRVGIARALAADP 153
|
170
....*....|...
gi 446516975 157 KVVIADEPTGNLD 169
Cdd:COG4525 154 RFLLMDEPFGALD 166
|
|
| AppF |
COG4608 |
ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism]; ... |
16-220 |
1.68e-40 |
|
ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443658 [Multi-domain] Cd Length: 329 Bit Score: 141.02 E-value: 1.68e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 16 KAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLAERDVPYFRRQLGVIFQD-FKLL-PK 93
Cdd:COG4608 32 KAVDGVSFDIRRGETLGLVGESGCGKSTLGRLLLRLEEPTSGEILFDGQDITGLSGRELRPLRRRMQMVFQDpYASLnPR 111
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 94 LTVYENVSFALEVIEEEPDA-IRERVTEVLGLVGL-EDRADALPSELSGGEQQRVAIARAIVNRPKVVIADEPTgnldie 171
Cdd:COG4608 112 MTVGDIIAEPLRIHGLASKAeRRERVAELLELVGLrPEHADRYPHEFSGGQRQRIGIARALALNPKLIVCDEPV------ 185
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 172 TALD------IMNIFTRI-NERGTTIVMATHNADIVNTIRHRVIAIEGGKIV----RDEI 220
Cdd:COG4608 186 SALDvsiqaqVLNLLEDLqDELGLTYLFISHDLSVVRHISDRVAVMYLGKIVeiapRDEL 245
|
|
| PRK13651 |
PRK13651 |
cobalt transporter ATP-binding subunit; Provisional |
2-218 |
2.38e-40 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184210 [Multi-domain] Cd Length: 305 Bit Score: 140.22 E-value: 2.38e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 2 IKMTNVYKEY----PNGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINV---------NGLTIET 68
Cdd:PRK13651 3 IKVKNIVKIFnkklPTELKALDNVSVEINQGEFIAIIGQTGSGKTTFIEHLNALLLPDTGTIEWifkdeknkkKTKEKEK 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 69 LAERDV---PYF---------RRQLGVIFQ--DFKLLpKLTVYENVSFALEVIEEEPDAIRERVTEVLGLVGL-EDRADA 133
Cdd:PRK13651 83 VLEKLViqkTRFkkikkikeiRRRVGVVFQfaEYQLF-EQTIEKDIIFGPVSMGVSKEEAKKRAAKYIELVGLdESYLQR 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 134 LPSELSGGEQQRVAIARAIVNRPKVVIADEPTGNLDIETALDIMNIFTRINERGTTIVMATHNADIVNTIRHRVIAIEGG 213
Cdd:PRK13651 162 SPFELSGGQKRRVALAGILAMEPDFLVFDEPTAGLDPQGVKEILEIFDNLNKQGKTIILVTHDLDNVLEWTKRTIFFKDG 241
|
....*
gi 446516975 214 KIVRD 218
Cdd:PRK13651 242 KIIKD 246
|
|
| ABC_drug_resistance_like |
cd03264 |
ABC-type multidrug transport system, ATPase component; The biological function of this family ... |
2-218 |
4.04e-40 |
|
ABC-type multidrug transport system, ATPase component; The biological function of this family is not well characterized, but display ABC domains similar to members of ABCA subfamily. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213231 [Multi-domain] Cd Length: 211 Bit Score: 136.55 E-value: 4.04e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 2 IKMTNVYKEYPNGmKAIAGLTVNIKQGEFVyVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIEtlaeRDVPYFRRQL 81
Cdd:cd03264 1 LQLENLTKRYGKK-RALDGVSLTLGPGMYG-LLGPNGAGKTTLMRILATLTPPSSGTIRIDGQDVL----KQPQKLRRRI 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 82 GVIFQDFKLLPKLTVYENVSFALEVIEEEPDAIRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIVNRPKVVIA 161
Cdd:cd03264 75 GYLPQEFGVYPNFTVREFLDYIAWLKGIPSKEVKARVDEVLELVNLGDRAKKKIGSLSGGMRRRVGIAQALVGDPSILIV 154
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 446516975 162 DEPTGNLDIETALDIMNIFTRINErGTTIVMATHNADIVNTIRHRVIAIEGGKIVRD 218
Cdd:cd03264 155 DEPTAGLDPEERIRFRNLLSELGE-DRIVILSTHIVEDVESLCNQVAVLNKGKLVFE 210
|
|
| ntrCD |
TIGR01184 |
nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits ... |
18-213 |
9.63e-40 |
|
nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits of nitrate transport in bacteria and archaea. This protein belongs to the ATP-binding cassette (ABC) superfamily. It is thought that the two subunits encoded by ntrC and ntrD form the binding surface for interaction with ATP. This model is restricted in identifying ATP binding subunit associated with the nitrate transport. Nitrate assimilation is aided by other proteins derived from the operon which among others include products of ntrA - a regulatory protein; ntrB - a hydropbobic transmembrane permease and narB - a reductase. [Transport and binding proteins, Anions, Transport and binding proteins, Other]
Pssm-ID: 130252 [Multi-domain] Cd Length: 230 Bit Score: 136.44 E-value: 9.63e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 18 IAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIetlaerDVPYFRRQlgVIFQDFKLLPKLTVY 97
Cdd:TIGR01184 1 LKGVNLTIQQGEFISLIGHSGCGKSTLLNLISGLAQPTSGGVILEGKQI------TEPGPDRM--VVFQNYSLLPWLTVR 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 98 ENVSFAL-EVIEEEPDAIRER-VTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIVNRPKVVIADEPTGNLDIETALD 175
Cdd:TIGR01184 73 ENIALAVdRVLPDLSKSERRAiVEEHIALVGLTEAADKRPGQLSGGMKQRVAIARALSIRPKVLLLDEPFGALDALTRGN 152
|
170 180 190
....*....|....*....|....*....|....*....
gi 446516975 176 IMNIFTRI-NERGTTIVMATHNADIVNTIRHRVIAIEGG 213
Cdd:TIGR01184 153 LQEELMQIwEEHRVTVLMVTHDVDEALLLSDRVVMLTNG 191
|
|
| PRK10619 |
PRK10619 |
histidine ABC transporter ATP-binding protein HisP; |
2-215 |
1.30e-39 |
|
histidine ABC transporter ATP-binding protein HisP;
Pssm-ID: 182592 [Multi-domain] Cd Length: 257 Bit Score: 137.02 E-value: 1.30e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 2 IKMTNVYKEYPNgMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLAERD-------- 73
Cdd:PRK10619 6 LNVIDLHKRYGE-HEVLKGVSLQANAGDVISIIGSSGSGKSTFLRCINFLEKPSEGSIVVNGQTINLVRDKDgqlkvadk 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 74 --VPYFRRQLGVIFQDFKLLPKLTVYENVSFA-LEVIEEEPDAIRERVTEVLGLVGLEDRA-DALPSELSGGEQQRVAIA 149
Cdd:PRK10619 85 nqLRLLRTRLTMVFQHFNLWSHMTVLENVMEApIQVLGLSKQEARERAVKYLAKVGIDERAqGKYPVHLSGGQQQRVSIA 164
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446516975 150 RAIVNRPKVVIADEPTGNLDIETALDIMNIFTRINERGTTIVMATHNADIVNTIRHRVIAIEGGKI 215
Cdd:PRK10619 165 RALAMEPEVLLFDEPTSALDPELVGEVLRIMQQLAEEGKTMVVVTHEMGFARHVSSHVIFLHQGKI 230
|
|
| ABC_subfamily_A |
cd03263 |
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily ... |
2-216 |
5.00e-39 |
|
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily mediates the transport of a variety of lipid compounds. Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency, degenerative retinopathies, and congenital keratinization disorders. The ABCA1 protein is involved in disorders of cholesterol transport and high-density lipoprotein (HDL) biosynthesis. The ABCA4 (ABCR) protein transports vitamin A derivatives in the outer segments of photoreceptor cells, and therefore, performs a crucial step in the visual cycle. The ABCA genes are not present in yeast. However, evolutionary studies of ABCA genes indicate that they arose as transporters that subsequently duplicated and that certain sets of ABCA genes were lost in different eukaryotic lineages.
Pssm-ID: 213230 [Multi-domain] Cd Length: 220 Bit Score: 134.17 E-value: 5.00e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 2 IKMTNVYKEYPNGMK-AIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETlaerDVPYFRRQ 80
Cdd:cd03263 1 LQIRNLTKTYKKGTKpAVDDLSLNVYKGEIFGLLGHNGAGKTTTLKMLTGELRPTSGTAYINGYSIRT----DRKAARQS 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 81 LGVIFQDFKLLPKLTVYENVSFALEVIEEEPDAIRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIVNRPKVVI 160
Cdd:cd03263 77 LGYCPQFDALFDELTVREHLRFYARLKGLPKSEIKEEVELLLRVLGLTDKANKRARTLSGGMKRKLSLAIALIGGPSVLL 156
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 446516975 161 ADEPTGNLDIETALDIMNIFTRInERGTTIVMATHNADIVNTIRHRVIAIEGGKIV 216
Cdd:cd03263 157 LDEPTSGLDPASRRAIWDLILEV-RKGRSIILTTHSMDEAEALCDRIAIMSDGKLR 211
|
|
| PRK10584 |
PRK10584 |
putative ABC transporter ATP-binding protein YbbA; Provisional |
18-212 |
5.78e-39 |
|
putative ABC transporter ATP-binding protein YbbA; Provisional
Pssm-ID: 182569 [Multi-domain] Cd Length: 228 Bit Score: 134.52 E-value: 5.78e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 18 IAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLAERDVPYFR-RQLGVIFQDFKLLPKLTV 96
Cdd:PRK10584 26 LTGVELVVKRGETIALIGESGSGKSTLLAILAGLDDGSSGEVSLVGQPLHQMDEEARAKLRaKHVGFVFQSFMLIPTLNA 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 97 YENVSF-ALEVIEEEPDAiRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIVNRPKVVIADEPTGNLDIETALD 175
Cdd:PRK10584 106 LENVELpALLRGESSRQS-RNGAKALLEQLGLGKRLDHLPAQLSGGEQQRVALARAFNGRPDVLFADEPTGNLDRQTGDK 184
|
170 180 190
....*....|....*....|....*....|....*...
gi 446516975 176 IMNIFTRIN-ERGTTIVMATHNADIVNTIRHRVIAIEG 212
Cdd:PRK10584 185 IADLLFSLNrEHGTTLILVTHDLQLAARCDRRLRLVNG 222
|
|
| ABC_NatA_sodium_exporter |
cd03266 |
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a ... |
1-216 |
6.34e-39 |
|
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of a single ATP-binding protein and a single integral membrane protein.
Pssm-ID: 213233 [Multi-domain] Cd Length: 218 Bit Score: 134.03 E-value: 6.34e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 1 MIKMTNVYKEYPN---GMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETlAERDVpyf 77
Cdd:cd03266 1 MITADALTKRFRDvkkTVQAVDGVSFTVKPGEVTGLLGPNGAGKTTTLRMLAGLLEPDAGFATVDGFDVVK-EPAEA--- 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 78 RRQLGVIFQDFKLLPKLTVYENVSFALEVIEEEPDAIRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIVNRPK 157
Cdd:cd03266 77 RRRLGFVSDSTGLYDRLTARENLEYFAGLYGLKGDELTARLEELADRLGMEELLDRRVGGFSTGMRQKVAIARALVHDPP 156
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 446516975 158 VVIADEPTGNLDIETALDIMNIFTRINERGTTIVMATHNADIVNTIRHRVIAIEGGKIV 216
Cdd:cd03266 157 VLLLDEPTTGLDVMATRALREFIRQLRALGKCILFSTHIMQEVERLCDRVVVLHRGRVV 215
|
|
| ugpC |
PRK11650 |
sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC; |
1-215 |
7.23e-39 |
|
sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;
Pssm-ID: 236947 [Multi-domain] Cd Length: 356 Bit Score: 137.28 E-value: 7.23e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 1 MIKMTNVYKEYPNGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETL--AERDVpyfr 78
Cdd:PRK11650 3 GLKLQAVRKSYDGKTQVIKGIDLDVADGEFIVLVGPSGCGKSTLLRMVAGLERITSGEIWIGGRVVNELepADRDI---- 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 79 rqlGVIFQDFKLLPKLTVYENVSFALEVIEEEPDAIRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIVNRPKV 158
Cdd:PRK11650 79 ---AMVFQNYALYPHMSVRENMAYGLKIRGMPKAEIEERVAEAARILELEPLLDRKPRELSGGQRQRVAMGRAIVREPAV 155
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446516975 159 VIADEPTGNLD----IETALDIMNIFTRInerGTTIVMATHnaDIVN--TIRHRVIAIEGGKI 215
Cdd:PRK11650 156 FLFDEPLSNLDaklrVQMRLEIQRLHRRL---KTTSLYVTH--DQVEamTLADRVVVMNGGVA 213
|
|
| CydD |
TIGR02857 |
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family ... |
2-195 |
9.63e-39 |
|
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex. Unfortunately, the gene symbol nomenclature adopted based on this operon in B. subtilis assigns cydC to the third gene in the operon where this gene is actually homologous to the E. coli cydD gene. We have chosen to name all homologs in this family in accordance with the precedence of publication of the E. coli name, CydD
Pssm-ID: 274323 [Multi-domain] Cd Length: 529 Bit Score: 140.11 E-value: 9.63e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 2 IKMTNVYKEYPNGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGltiETLAERDVPYFRRQL 81
Cdd:TIGR02857 322 LEFSGVSVAYPGRRPALRPVSFTVPPGERVALVGPSGAGKSTLLNLLLGFVDPTEGSIAVNG---VPLADADADSWRDQI 398
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 82 GVIFQDFKLLPKlTVYENVSFAlevieeEPDAIRERVTEVLGLVGLEDRADALP-----------SELSGGEQQRVAIAR 150
Cdd:TIGR02857 399 AWVPQHPFLFAG-TIAENIRLA------RPDASDAEIREALERAGLDEFVAALPqgldtpigeggAGLSGGQAQRLALAR 471
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 446516975 151 AIVNRPKVVIADEPTGNLDIETALDIMNIFTRInERGTTIVMATH 195
Cdd:TIGR02857 472 AFLRDAPLLLLDEPTAHLDAETEAEVLEALRAL-AQGRTVLLVTH 515
|
|
| YejF |
COG4172 |
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ... |
16-216 |
1.50e-38 |
|
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 443332 [Multi-domain] Cd Length: 533 Bit Score: 139.82 E-value: 1.50e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 16 KAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEkPSTGSINVNGLTIETLAERDVPYFRRQLGVIFQD-F-KLLPK 93
Cdd:COG4172 300 KAVDGVSLTLRRGETLGLVGESGSGKSTLGLALLRLI-PSEGEIRFDGQDLDGLSRRALRPLRRRMQVVFQDpFgSLSPR 378
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 94 LTVYENVSFALEVIEEEPDA--IRERVTEVLGLVGL-EDRADALPSELSGGEQQRVAIARAIVNRPKVVIADEPTGNLDI 170
Cdd:COG4172 379 MTVGQIIAEGLRVHGPGLSAaeRRARVAEALEEVGLdPAARHRYPHEFSGGQRQRIAIARALILEPKLLVLDEPTSALDV 458
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 446516975 171 ETALDIMNIFTRIN-ERGTTIVMATHNADIVNTIRHRVIAIEGGKIV 216
Cdd:COG4172 459 SVQAQILDLLRDLQrEHGLAYLFISHDLAVVRALAHRVMVMKDGKVV 505
|
|
| cbiO |
PRK13647 |
cobalt transporter ATP-binding subunit; Provisional |
2-216 |
2.80e-38 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237457 [Multi-domain] Cd Length: 274 Bit Score: 133.71 E-value: 2.80e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 2 IKMTNVYKEYPNGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLAERDVpyfRRQL 81
Cdd:PRK13647 5 IEVEDLHFRYKDGTKALKGLSLSIPEGSKTALLGPNGAGKSTLLLHLNGIYLPQRGRVKVMGREVNAENEKWV---RSKV 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 82 GVIFQDfkllP-----KLTVYENVSFALEVIEEEPDAIRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIVNRP 156
Cdd:PRK13647 82 GLVFQD----PddqvfSSTVWDDVAFGPVNMGLDKDEVERRVEEALKAVRMWDFRDKPPYHLSYGQKKRVAIAGVLAMDP 157
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 157 KVVIADEPTGNLDIETALDIMNIFTRINERGTTIVMATHNADIVNTIRHRVIAIEGGKIV 216
Cdd:PRK13647 158 DVIVLDEPMAYLDPRGQETLMEILDRLHNQGKTVIVATHDVDLAAEWADQVIVLKEGRVL 217
|
|
| HisP |
COG4598 |
ABC-type histidine transport system, ATPase component [Amino acid transport and metabolism]; |
1-195 |
3.19e-38 |
|
ABC-type histidine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443652 [Multi-domain] Cd Length: 259 Bit Score: 133.39 E-value: 3.19e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 1 MIKMTNVYKEYpNGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLAERD------- 73
Cdd:COG4598 8 ALEVRDLHKSF-GDLEVLKGVSLTARKGDVISIIGSSGSGKSTFLRCINLLETPDSGEIRVGGEEIRLKPDRDgelvpad 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 74 ---VPYFRRQLGVIFQDFKLLPKLTVYENVSFA-LEVIEEEPDAIRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIA 149
Cdd:COG4598 87 rrqLQRIRTRLGMVFQSFNLWSHMTVLENVIEApVHVLGRPKAEAIERAEALLAKVGLADKRDAYPAHLSGGQQQRAAIA 166
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 446516975 150 RAIVNRPKVVIADEPTGNLDIETALDIMNIFTRINERGTTIVMATH 195
Cdd:COG4598 167 RALAMEPEVMLFDEPTSALDPELVGEVLKVMRDLAEEGRTMLVVTH 212
|
|
| cbiO |
PRK13639 |
cobalt transporter ATP-binding subunit; Provisional |
1-217 |
6.87e-38 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184199 [Multi-domain] Cd Length: 275 Bit Score: 132.89 E-value: 6.87e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 1 MIKMTNVYKEYPNGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIEtLAERDVPYFRRQ 80
Cdd:PRK13639 1 ILETRDLKYSYPDGTEALKGINFKAEKGEMVALLGPNGAGKSTLFLHFNGILKPTSGEVLIKGEPIK-YDKKSLLEVRKT 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 81 LGVIFQ--DFKLLPKlTVYENVSFA---LEVIEEEpdaIRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIVNR 155
Cdd:PRK13639 80 VGIVFQnpDDQLFAP-TVEEDVAFGplnLGLSKEE---VEKRVKEALKAVGMEGFENKPPHHLSGGQKKRVAIAGILAMK 155
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446516975 156 PKVVIADEPTGNLDIETALDIMNIFTRINERGTTIVMATHNADIVNTIRHRVIAIEGGKIVR 217
Cdd:PRK13639 156 PEIIVLDEPTSGLDPMGASQIMKLLYDLNKEGITIIISTHDVDLVPVYADKVYVMSDGKIIK 217
|
|
| ABC_TM1139_LivF_branched |
cd03224 |
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of ... |
17-216 |
1.87e-37 |
|
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of the LIV-I bacterial ABC-type two-component transport system that imports neutral, branched-chain amino acids. The E. coli branched-chain amino acid transporter comprises a heterodimer of ABC transporters (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules.
Pssm-ID: 213191 [Multi-domain] Cd Length: 222 Bit Score: 130.25 E-value: 1.87e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 17 AIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLAERDVPyfRRQLGVIFQDFKLLPKLTV 96
Cdd:cd03224 15 ILFGVSLTVPEGEIVALLGRNGAGKTTLLKTIMGLLPPRSGSIRFDGRDITGLPPHERA--RAGIGYVPEGRRIFPELTV 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 97 YENVSFALEVIEeePDAIRERVTEVLGLV-GLEDRADALPSELSGGEQQRVAIARAIVNRPKVVIADEPTGNLDIETALD 175
Cdd:cd03224 93 EENLLLGAYARR--RAKRKARLERVYELFpRLKERRKQLAGTLSGGEQQMLAIARALMSRPKLLLLDEPSEGLAPKIVEE 170
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 446516975 176 IMNIFTRINERGTTIVMATHNADIVNTIRHRVIAIEGGKIV 216
Cdd:cd03224 171 IFEAIRELRDEGVTILLVEQNARFALEIADRAYVLERGRVV 211
|
|
| ABC_DrrA |
cd03265 |
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein ... |
2-216 |
1.91e-37 |
|
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein component of a bacterial exporter complex that confers resistance to the antibiotics daunorubicin and doxorubicin. In addition to DrrA, the complex includes an integral membrane protein called DrrB. DrrA belongs to the ABC family of transporters and shares sequence and functional similarities with a protein found in cancer cells called P-glycoprotein. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213232 [Multi-domain] Cd Length: 220 Bit Score: 130.18 E-value: 1.91e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 2 IKMTNVYKEYpNGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIEtlaeRDVPYFRRQL 81
Cdd:cd03265 1 IEVENLVKKY-GDFEAVRGVSFRVRRGEIFGLLGPNGAGKTTTIKMLTTLLKPTSGRATVAGHDVV----REPREVRRRI 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 82 GVIFQDFKLLPKLTVYENVSFALEVIEEEPDAIRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIVNRPKVVIA 161
Cdd:cd03265 76 GIVFQDLSVDDELTGWENLYIHARLYGVPGAERRERIDELLDFVGLLEAADRLVKTYSGGMRRRLEIARSLVHRPEVLFL 155
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 446516975 162 DEPTGNLDIETALDIMNIFTRINER-GTTIVMATHNADIVNTIRHRVIAIEGGKIV 216
Cdd:cd03265 156 DEPTIGLDPQTRAHVWEYIEKLKEEfGMTILLTTHYMEEAEQLCDRVAIIDHGRII 211
|
|
| PRK11000 |
PRK11000 |
maltose/maltodextrin ABC transporter ATP-binding protein MalK; |
2-215 |
5.20e-37 |
|
maltose/maltodextrin ABC transporter ATP-binding protein MalK;
Pssm-ID: 182893 [Multi-domain] Cd Length: 369 Bit Score: 132.85 E-value: 5.20e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 2 IKMTNVYKEYpnGMKAIA-GLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGltietlaER--DVPYFR 78
Cdd:PRK11000 4 VTLRNVTKAY--GDVVISkDINLDIHEGEFVVFVGPSGCGKSTLLRMIAGLEDITSGDLFIGE-------KRmnDVPPAE 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 79 RQLGVIFQDFKLLPKLTVYENVSFALEVIEEEPDAIRERVT---EVLGLVGLEDRadaLPSELSGGEQQRVAIARAIVNR 155
Cdd:PRK11000 75 RGVGMVFQSYALYPHLSVAENMSFGLKLAGAKKEEINQRVNqvaEVLQLAHLLDR---KPKALSGGQRQRVAIGRTLVAE 151
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446516975 156 PKVVIADEPTGNLDieTALDI-MNI-FTRINER-GTTIVMATHNADIVNTIRHRVIAIEGGKI 215
Cdd:PRK11000 152 PSVFLLDEPLSNLD--AALRVqMRIeISRLHKRlGRTMIYVTHDQVEAMTLADKIVVLDAGRV 212
|
|
| nikE |
PRK10419 |
nickel ABC transporter ATP-binding protein NikE; |
20-218 |
9.98e-37 |
|
nickel ABC transporter ATP-binding protein NikE;
Pssm-ID: 236689 [Multi-domain] Cd Length: 268 Bit Score: 129.81 E-value: 9.98e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 20 GLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLAERDVPYFRRQLGVIFQDF--KLLPKLTVY 97
Cdd:PRK10419 30 NVSLSLKSGETVALLGRSGCGKSTLARLLVGLESPSQGNVSWRGEPLAKLNRAQRKAFRRDIQMVFQDSisAVNPRKTVR 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 98 ENVSFALEVIEEEPDAIRE-RVTEVLGLVGLEDR-ADALPSELSGGEQQRVAIARAIVNRPKVVIADEPTGNLDIETALD 175
Cdd:PRK10419 110 EIIREPLRHLLSLDKAERLaRASEMLRAVDLDDSvLDKRPPQLSGGQLQRVCLARALAVEPKLLILDEAVSNLDLVLQAG 189
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 446516975 176 IMNIFTRINER-GTTIVMATHNADIVNTIRHRVIAIEGGKIVRD 218
Cdd:PRK10419 190 VIRLLKKLQQQfGTACLFITHDLRLVERFCQRVMVMDNGQIVET 233
|
|
| YnjD |
COG4136 |
ABC-type uncharacterized transport system YnjBCD, ATPase component [General function ... |
18-198 |
1.77e-36 |
|
ABC-type uncharacterized transport system YnjBCD, ATPase component [General function prediction only];
Pssm-ID: 443311 [Multi-domain] Cd Length: 211 Bit Score: 127.21 E-value: 1.77e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 18 IAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKP---STGSINVNGLTIETLaerdvPYFRRQLGVIFQDFKLLPKL 94
Cdd:COG4136 17 LAPLSLTVAPGEILTLMGPSGSGKSTLLAAIAGTLSPafsASGEVLLNGRRLTAL-----PAEQRRIGILFQDDLLFPHL 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 95 TVYENVSFALevieeePDAI-----RERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIVNRPKVVIADEPTGNLD 169
Cdd:COG4136 92 SVGENLAFAL------PPTIgraqrRARVEQALEEAGLAGFADRDPATLSGGQRARVALLRALLAEPRALLLDEPFSKLD 165
|
170 180 190
....*....|....*....|....*....|
gi 446516975 170 IETALDIMN-IFTRINERGTTIVMATHNAD 198
Cdd:COG4136 166 AALRAQFREfVFEQIRQRGIPALLVTHDEE 195
|
|
| ssuB |
PRK11247 |
aliphatic sulfonates transport ATP-binding subunit; Provisional |
20-215 |
2.03e-36 |
|
aliphatic sulfonates transport ATP-binding subunit; Provisional
Pssm-ID: 183055 [Multi-domain] Cd Length: 257 Bit Score: 128.64 E-value: 2.03e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 20 GLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSInVNGLTieTLAErdvpyFRRQLGVIFQDFKLLPKLTVYEN 99
Cdd:PRK11247 30 QLDLHIPAGQFVAVVGRSGCGKSTLLRLLAGLETPSAGEL-LAGTA--PLAE-----AREDTRLMFQDARLLPWKKVIDN 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 100 VSFALEvieeepDAIRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIVNRPKVVIADEPTGNLDIETALDIMNI 179
Cdd:PRK11247 102 VGLGLK------GQWRDAALQALAAVGLADRANEWPAALSGGQKQRVALARALIHRPGLLLLDEPLGALDALTRIEMQDL 175
|
170 180 190
....*....|....*....|....*....|....*..
gi 446516975 180 FTRI-NERGTTIVMATHNADIVNTIRHRVIAIEGGKI 215
Cdd:PRK11247 176 IESLwQQHGFTVLLVTHDVSEAVAMADRVLLIEEGKI 212
|
|
| ABC_ThiQ_thiamine_transporter |
cd03298 |
ATP-binding cassette domain of the thiamine transport system; Part of the ... |
21-218 |
2.43e-36 |
|
ATP-binding cassette domain of the thiamine transport system; Part of the binding-protein-dependent transport system tbpA-thiPQ for thiamine and TPP. Probably responsible for the translocation of thiamine across the membrane. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213265 [Multi-domain] Cd Length: 211 Bit Score: 127.22 E-value: 2.43e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 21 LTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLaerdvPYFRRQLGVIFQDFKLLPKLTVYENV 100
Cdd:cd03298 17 FDLTFAQGEITAIVGPSGSGKSTLLNLIAGFETPQSGRVLINGVDVTAA-----PPADRPVSMLFQENNLFAHLTVEQNV 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 101 SFA----LEVIEEEpdaiRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIVNRPKVVIADEPTGNLDIETALDI 176
Cdd:cd03298 92 GLGlspgLKLTAED----RQAIEVALARVGLAGLEKRLPGELSGGERQRVALARVLVRDKPVLLLDEPFAALDPALRAEM 167
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 446516975 177 MNIFTRIN-ERGTTIVMATHNADIVNTIRHRVIAIEGGKIVRD 218
Cdd:cd03298 168 LDLVLDLHaETKMTVLMVTHQPEDAKRLAQRVVFLDNGRIAAQ 210
|
|
| ABCC_ATM1_transporter |
cd03253 |
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC ... |
2-216 |
2.95e-36 |
|
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC transporter that is expressed in the mitochondria. Although the specific function of ATM1 is unknown, its disruption results in the accumulation of excess mitochondrial iron, loss of mitochondrial cytochromes, oxidative damage to mitochondrial DNA, and decreased levels of cytosolic heme proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213220 [Multi-domain] Cd Length: 236 Bit Score: 127.35 E-value: 2.95e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 2 IKMTNVYKEYPNGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLaerDVPYFRRQL 81
Cdd:cd03253 1 IEFENVTFAYDPGRPVLKDVSFTIPAGKKVAIVGPSGSGKSTILRLLFRFYDVSSGSILIDGQDIREV---TLDSLRRAI 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 82 GVIFQDFKLLPKlTVYENVSFAlevieeEPDAIRERVTEVLGLVGLEDRADALPS-----------ELSGGEQQRVAIAR 150
Cdd:cd03253 78 GVVPQDTVLFND-TIGYNIRYG------RPDATDEEVIEAAKAAQIHDKIMRFPDgydtivgerglKLSGGEKQRVAIAR 150
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446516975 151 AIVNRPKVVIADEPTGNLDIETALDIMNIFTRINERGTTIVMAtHNadiVNTIRH--RVIAIEGGKIV 216
Cdd:cd03253 151 AILKNPPILLLDEATSALDTHTEREIQAALRDVSKGRTTIVIA-HR---LSTIVNadKIIVLKDGRIV 214
|
|
| ModF |
COG1119 |
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA ... |
1-218 |
5.28e-36 |
|
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA [Inorganic ion transport and metabolism];
Pssm-ID: 440736 [Multi-domain] Cd Length: 250 Bit Score: 127.12 E-value: 5.28e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 1 MIKMTNVYKEYpNGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGsinvNGLTI--ETLAERDVPYFR 78
Cdd:COG1119 3 LLELRNVTVRR-GGKTILDDISWTVKPGEHWAILGPNGAGKSTLLSLITGDLPPTYG----NDVRLfgERRGGEDVWELR 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 79 RQLGVIFQDfkLLPKLTVYENVsfaLEVI-----------EEEPDAIRERVTEVLGLVGLEDRADALPSELSGGEQQRVA 147
Cdd:COG1119 78 KRIGLVSPA--LQLRFPRDETV---LDVVlsgffdsiglyREPTDEQRERARELLELLGLAHLADRPFGTLSQGEQRRVL 152
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446516975 148 IARAIVNRPKVVIADEPTGNLDIETALDIMNIFTRINERG-TTIVMATHNA-DIVNTIRHrVIAIEGGKIVRD 218
Cdd:COG1119 153 IARALVKDPELLILDEPTAGLDLGARELLLALLDKLAAEGaPTLVLVTHHVeEIPPGITH-VLLLKDGRVVAA 224
|
|
| cbiO |
PRK13637 |
energy-coupling factor transporter ATPase; |
2-216 |
5.87e-36 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237455 [Multi-domain] Cd Length: 287 Bit Score: 128.24 E-value: 5.87e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 2 IKMTNVYKEYPNGM----KAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIeTLAERDVPYF 77
Cdd:PRK13637 3 IKIENLTHIYMEGTpfekKALDNVNIEIEDGEFVGLIGHTGSGKSTLIQHLNGLLKPTSGKIIIDGVDI-TDKKVKLSDI 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 78 RRQLGVIFQ--DFKLLPKlTVYENVSFALEVIEEEPDAIRERVTEVLGLVGL--EDRADALPSELSGGEQQRVAIARAIV 153
Cdd:PRK13637 82 RKKVGLVFQypEYQLFEE-TIEKDIAFGPINLGLSEEEIENRVKRAMNIVGLdyEDYKDKSPFELSGGQKRRVAIAGVVA 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446516975 154 NRPKVVIADEPTGNLDIETALDIMNIFTRINER-GTTIVMATHNADIVNTIRHRVIAIEGGKIV 216
Cdd:PRK13637 161 MEPKILILDEPTAGLDPKGRDEILNKIKELHKEyNMTIILVSHSMEDVAKLADRIIVMNKGKCE 224
|
|
| PRK10851 |
PRK10851 |
sulfate/thiosulfate ABC transporter ATP-binding protein CysA; |
2-215 |
7.81e-36 |
|
sulfate/thiosulfate ABC transporter ATP-binding protein CysA;
Pssm-ID: 182778 [Multi-domain] Cd Length: 353 Bit Score: 129.43 E-value: 7.81e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 2 IKMTNVYKEYPNgMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLAERDvpyfrRQL 81
Cdd:PRK10851 3 IEIANIKKSFGR-TQVLNDISLDIPSGQMVALLGPSGSGKTTLLRIIAGLEHQTSGHIRFHGTDVSRLHARD-----RKV 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 82 GVIFQDFKLLPKLTVYENVSFALEVI--EEEPD--AIRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIVNRPK 157
Cdd:PRK10851 77 GFVFQHYALFRHMTVFDNIAFGLTVLprRERPNaaAIKAKVTQLLEMVQLAHLADRYPAQLSGGQKQRVALARALAVEPQ 156
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 446516975 158 VVIADEPTGNLDIETALDIMNIFTRINER-GTTIVMATHNADIVNTIRHRVIAIEGGKI 215
Cdd:PRK10851 157 ILLLDEPFGALDAQVRKELRRWLRQLHEElKFTSVFVTHDQEEAMEVADRVVVMSQGNI 215
|
|
| nickel_nikE |
TIGR02769 |
nickel import ATP-binding protein NikE; This family represents the NikE subunit of a ... |
20-216 |
1.36e-35 |
|
nickel import ATP-binding protein NikE; This family represents the NikE subunit of a multisubunit nickel import ABC transporter complex. Nickel, once imported, may be used in urease and in certain classes of hydrogenase and superoxide dismutase. [Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 131816 [Multi-domain] Cd Length: 265 Bit Score: 126.84 E-value: 1.36e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 20 GLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLAERDVPYFRRQLGVIFQDF--KLLPKLTVY 97
Cdd:TIGR02769 29 NVSLSIEEGETVGLLGRSGCGKSTLARLLLGLEKPAQGTVSFRGQDLYQLDRKQRRAFRRDVQLVFQDSpsAVNPRMTVR 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 98 ENVSFALEVIEEEPDAIRE-RVTEVLGLVGLEDR-ADALPSELSGGEQQRVAIARAIVNRPKVVIADEPTGNLDIETALD 175
Cdd:TIGR02769 109 QIIGEPLRHLTSLDESEQKaRIAELLDMVGLRSEdADKLPRQLSGGQLQRINIARALAVKPKLIVLDEAVSNLDMVLQAV 188
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 446516975 176 IMNIFTRINER-GTTIVMATHNADIVNTIRHRVIAIEGGKIV 216
Cdd:TIGR02769 189 ILELLRKLQQAfGTAYLFITHDLRLVQSFCQRVAVMDKGQIV 230
|
|
| cbiO |
PRK13635 |
energy-coupling factor ABC transporter ATP-binding protein; |
2-216 |
2.01e-35 |
|
energy-coupling factor ABC transporter ATP-binding protein;
Pssm-ID: 184195 [Multi-domain] Cd Length: 279 Bit Score: 126.67 E-value: 2.01e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 2 IKMTNVYKEYPNGMK-AIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTietLAERDVPYFRRQ 80
Cdd:PRK13635 6 IRVEHISFRYPDAATyALKDVSFSVYEGEWVAIVGHNGSGKSTLAKLLNGLLLPEAGTITVGGMV---LSEETVWDVRRQ 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 81 LGVIFQDfkllPK-----LTVYENVSFALEVIEEEPDAIRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIVNR 155
Cdd:PRK13635 83 VGMVFQN----PDnqfvgATVQDDVAFGLENIGVPREEMVERVDQALRQVGMEDFLNREPHRLSGGQKQRVAIAGVLALQ 158
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446516975 156 PKVVIADEPTGNLDIETALDIMNIFTRIN-ERGTTIVMATHNADIVNTiRHRVIAIEGGKIV 216
Cdd:PRK13635 159 PDIIILDEATSMLDPRGRREVLETVRQLKeQKGITVLSITHDLDEAAQ-ADRVIVMNKGEIL 219
|
|
| PRK13633 |
PRK13633 |
energy-coupling factor transporter ATPase; |
1-218 |
2.07e-35 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237453 [Multi-domain] Cd Length: 280 Bit Score: 126.74 E-value: 2.07e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 1 MIKMTNVYKEYPNGMK-----AIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLtiETLAERDVP 75
Cdd:PRK13633 4 MIKCKNVSYKYESNEEsteklALDDVNLEVKKGEFLVILGRNGSGKSTIAKHMNALLIPSEGKVYVDGL--DTSDEENLW 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 76 YFRRQLGVIFQ--DFKLLPKLtVYENVSFALEVIEEEPDAIRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIV 153
Cdd:PRK13633 82 DIRNKAGMVFQnpDNQIVATI-VEEDVAFGPENLGIPPEEIRERVDESLKKVGMYEYRRHAPHLLSGGQKQRVAIAGILA 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446516975 154 NRPKVVIADEPTGNLDIETALDIMNIFTRINER-GTTIVMATH------NADivntirhRVIAIEGGKIVRD 218
Cdd:PRK13633 161 MRPECIIFDEPTAMLDPSGRREVVNTIKELNKKyGITIILITHymeeavEAD-------RIIVMDSGKVVME 225
|
|
| ABC_MTABC3_MDL1_MDL2 |
cd03249 |
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 ... |
2-216 |
3.10e-35 |
|
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 (also known as ABCB6) is a mitochondrial ATP-binding cassette protein involved in iron homeostasis and one of four ABC transporters expressed in the mitochondrial inner membrane, the other three being MDL1(ABC7), MDL2, and ATM1. In fact, the yeast MDL1 (multidrug resistance-like protein 1) and MDL2 (multidrug resistance-like protein 2) transporters are also included in this CD. MDL1 is an ATP-dependent permease that acts as a high-copy suppressor of ATM1 and is thought to have a role in resistance to oxidative stress. Interestingly, subfamily B is more closely related to the carboxyl-terminal component of subfamily C than the two halves of ABCC molecules are with one another.
Pssm-ID: 213216 [Multi-domain] Cd Length: 238 Bit Score: 124.96 E-value: 3.10e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 2 IKMTNVYKEYPN--GMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLAerdVPYFRR 79
Cdd:cd03249 1 IEFKNVSFRYPSrpDVPILKGLSLTIPPGKTVALVGSSGCGKSTVVSLLERFYDPTSGEILLDGVDIRDLN---LRWLRS 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 80 QLGVIFQDfkllPKL---TVYENVSFALevieeePDAIRERVTEVLGLVGLEDRADALP-----------SELSGGEQQR 145
Cdd:cd03249 78 QIGLVSQE----PVLfdgTIAENIRYGK------PDATDEEVEEAAKKANIHDFIMSLPdgydtlvgergSQLSGGQKQR 147
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446516975 146 VAIARAIVNRPKVVIADEPTGNLDIETALDIMNIFTRINERGTTIVMAtHNadiVNTIRH--RVIAIEGGKIV 216
Cdd:cd03249 148 IAIARALLRNPKILLLDEATSALDAESEKLVQEALDRAMKGRTTIVIA-HR---LSTIRNadLIAVLQNGQVV 216
|
|
| fbpC |
PRK11432 |
ferric ABC transporter ATP-binding protein; |
18-169 |
3.23e-35 |
|
ferric ABC transporter ATP-binding protein;
Pssm-ID: 183133 [Multi-domain] Cd Length: 351 Bit Score: 127.91 E-value: 3.23e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 18 IAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGltiETLAERDVPyfRRQLGVIFQDFKLLPKLTVY 97
Cdd:PRK11432 22 IDNLNLTIKQGTMVTLLGPSGCGKTTVLRLVAGLEKPTEGQIFIDG---EDVTHRSIQ--QRDICMVFQSYALFPHMSLG 96
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446516975 98 ENVSFALEVIEEEPDAIRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIVNRPKVVIADEPTGNLD 169
Cdd:PRK11432 97 ENVGYGLKMLGVPKEERKQRVKEALELVDLAGFEDRYVDQISGGQQQRVALARALILKPKVLLFDEPLSNLD 168
|
|
| ModC |
COG4148 |
ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and ... |
33-217 |
4.34e-35 |
|
ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and metabolism]; ABC-type molybdate transport system, ATPase component ModC is part of the Pathway/BioSystem: Molybdopterin biosynthesis
Pssm-ID: 443319 [Multi-domain] Cd Length: 358 Bit Score: 127.52 E-value: 4.34e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 33 VVGPSGAGKSTFIKMMYREEKPSTGSINVNGltiETL----AERDVPYFRRQLGVIFQDFKLLPKLTVYENVSFALEVIE 108
Cdd:COG4148 30 LFGPSGSGKTTLLRAIAGLERPDSGRIRLGG---EVLqdsaRGIFLPPHRRRIGYVFQEARLFPHLSVRGNLLYGRKRAP 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 109 EEPDAIR-ERVTEVLGLVGLEDRAdalPSELSGGEQQRVAIARAIVNRPKVVIADEPTGNLDIETALDIMNIFTRINER- 186
Cdd:COG4148 107 RAERRISfDEVVELLGIGHLLDRR---PATLSGGERQRVAIGRALLSSPRLLLMDEPLAALDLARKAEILPYLERLRDEl 183
|
170 180 190
....*....|....*....|....*....|.
gi 446516975 187 GTTIVMATHNADIVNTIRHRVIAIEGGKIVR 217
Cdd:COG4148 184 DIPILYVSHSLDEVARLADHVVLLEQGRVVA 214
|
|
| PRK09984 |
PRK09984 |
phosphonate ABC transporter ATP-binding protein; |
1-218 |
6.48e-35 |
|
phosphonate ABC transporter ATP-binding protein;
Pssm-ID: 182182 [Multi-domain] Cd Length: 262 Bit Score: 124.74 E-value: 6.48e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 1 MIKMTNVYKEYpNGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMM---YREEKPSTGSINVNGLTIETLAE--RDVP 75
Cdd:PRK09984 4 IIRVEKLAKTF-NQHQALHAVDLNIHHGEMVALLGPSGSGKSTLLRHLsglITGDKSAGSHIELLGRTVQREGRlaRDIR 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 76 YFRRQLGVIFQDFKLLPKLTVYENV--------SFALEVIEEEPDAIRERVTEVLGLVGLEDRADALPSELSGGEQQRVA 147
Cdd:PRK09984 83 KSRANTGYIFQQFNLVNRLSVLENVligalgstPFWRTCFSWFTREQKQRALQALTRVGMVHFAHQRVSTLSGGQQQRVA 162
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446516975 148 IARAIVNRPKVVIADEPTGNLDIETALDIMNIFTRINER-GTTIVMATHNADIVNTIRHRVIAIEGGKIVRD 218
Cdd:PRK09984 163 IARALMQQAKVILADEPIASLDPESARIVMDTLRDINQNdGITVVVTLHQVDYALRYCERIVALRQGHVFYD 234
|
|
| ABCC_Glucan_exporter_like |
cd03254 |
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan ... |
2-216 |
6.84e-35 |
|
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan exporter ATP-binding protein. In A. tumefaciens cyclic beta-1, 2-glucan must be transported into the periplasmic space to exert its action as a virulence factor. This subfamily belongs to the MRP-like family and is involved in drug, peptide, and lipid export. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains each composed of six transmembrane (TM) helices and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213221 [Multi-domain] Cd Length: 229 Bit Score: 123.87 E-value: 6.84e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 2 IKMTNVYKEYPNGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLAERDVpyfRRQL 81
Cdd:cd03254 3 IEFENVNFSYDEKKPVLKDINFSIKPGETVAIVGPTGAGKTTLINLLMRFYDPQKGQILIDGIDIRDISRKSL---RSMI 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 82 GVIFQDFKLLPKlTVYENVSFAlevieeEPDAIRERVTEVLGLVGLEDRADALP-----------SELSGGEQQRVAIAR 150
Cdd:cd03254 80 GVVLQDTFLFSG-TIMENIRLG------RPNATDEEVIEAAKEAGAHDFIMKLPngydtvlgengGNLSQGERQLLAIAR 152
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446516975 151 AIVNRPKVVIADEPTGNLDIETALDIMNIFTRINERGTTIVMATHnadiVNTIRH--RVIAIEGGKIV 216
Cdd:cd03254 153 AMLRDPKILILDEATSNIDTETEKLIQEALEKLMKGRTSIIIAHR----LSTIKNadKILVLDDGKII 216
|
|
| cbiO |
PRK13632 |
cobalt transporter ATP-binding subunit; Provisional |
1-217 |
7.32e-35 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237452 [Multi-domain] Cd Length: 271 Bit Score: 124.72 E-value: 7.32e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 1 MIKMTNVYKEYPNGMK-AIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIetlAERDVPYFRR 79
Cdd:PRK13632 7 MIKVENVSFSYPNSENnALKNVSFEINEGEYVAILGHNGSGKSTISKILTGLLKPQSGEIKIDGITI---SKENLKEIRK 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 80 QLGVIFQDfkllPK-----LTVYENVSFALEVIEEEPDAIRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIVN 154
Cdd:PRK13632 84 KIGIIFQN----PDnqfigATVEDDIAFGLENKKVPPKKMKDIIDDLAKKVGMEDYLDKEPQNLSGGQKQRVAIASVLAL 159
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446516975 155 RPKVVIADEPTGNLDIETALDIMNIFTRINERGT-TIVMATHNADIVnTIRHRVIAIEGGKIVR 217
Cdd:PRK13632 160 NPEIIIFDESTSMLDPKGKREIKKIMVDLRKTRKkTLISITHDMDEA-ILADKVIVFSEGKLIA 222
|
|
| ABCC_Hemolysin |
cd03252 |
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a ... |
2-218 |
8.75e-35 |
|
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a central component of the secretion machinery that translocates the toxin, hemolysin A, in a Sec-independent fashion across both membranes of E. coli. The hemolysin A (HlyA) transport machinery is composed of the ATP-binding cassette (ABC) transporter HlyB located in the inner membrane, hemolysin D (HlyD), also anchored in the inner membrane, and TolC, which resides in the outer membrane. HlyD apparently forms a continuous channel that bridges the entire periplasm, interacting with TolC and HlyB. This arrangement prevents the appearance of periplasmic intermediates of HlyA during substrate transport. Little is known about the molecular details of HlyA transport, but it is evident that ATP-hydrolysis by the ABC-transporter HlyB is a necessary source of energy.
Pssm-ID: 213219 [Multi-domain] Cd Length: 237 Bit Score: 123.75 E-value: 8.75e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 2 IKMTNVYKEY-PNGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLaerDVPYFRRQ 80
Cdd:cd03252 1 ITFEHVRFRYkPDGPVILDNISLRIKPGEVVGIVGRSGSGKSTLTKLIQRFYVPENGRVLVDGHDLALA---DPAWLRRQ 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 81 LGVIFQDFKLLPKlTVYENVSFAlevieeEPDAIRERVTEVLGLVGLEDRADALP-----------SELSGGEQQRVAIA 149
Cdd:cd03252 78 VGVVLQENVLFNR-SIRDNIALA------DPGMSMERVIEAAKLAGAHDFISELPegydtivgeqgAGLSGGQRQRIAIA 150
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446516975 150 RAIVNRPKVVIADEPTGNLDIETALDIMNIFTRINERGTTIVMATHNADIVNTirHRVIAIEGGKIVRD 218
Cdd:cd03252 151 RALIHNPRILIFDEATSALDYESEHAIMRNMHDICAGRTVIIIAHRLSTVKNA--DRIIVMEKGRIVEQ 217
|
|
| ABCC_bacteriocin_exporters |
cd03245 |
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic ... |
6-218 |
2.03e-34 |
|
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic bacteriocins of lactic acid bacteria are produced as precursors which have N-terminal leader peptides that share similarities in amino acid sequence and contain a conserved processing site of two glycine residues in positions -1 and -2. A dedicated ATP-binding cassette (ABC) transporter is responsible for the proteolytic cleavage of the leader peptides and subsequent translocation of the bacteriocins across the cytoplasmic membrane.
Pssm-ID: 213212 [Multi-domain] Cd Length: 220 Bit Score: 122.31 E-value: 2.03e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 6 NVYKEYPNG-MKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLAERDVpyfRRQLGVI 84
Cdd:cd03245 7 NVSFSYPNQeIPALDNVSLTIRAGEKVAIIGRVGSGKSTLLKLLAGLYKPTSGSVLLDGTDIRQLDPADL---RRNIGYV 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 85 FQDFKLLpKLTVYENVSFALevieeePDAIRERVTEVLGLVGLEDRADALP-----------SELSGGEQQRVAIARAIV 153
Cdd:cd03245 84 PQDVTLF-YGTLRDNITLGA------PLADDERILRAAELAGVTDFVNKHPngldlqigergRGLSGGQRQAVALARALL 156
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 154 NRPKVVIADEPTGNLDIETAldiMNIFTRINE--RGTTIVMATHNA---DIVNtirhRVIAIEGGKIVRD 218
Cdd:cd03245 157 NDPPILLLDEPTSAMDMNSE---ERLKERLRQllGDKTLIIITHRPsllDLVD----RIIVMDSGRIVAD 219
|
|
| thiQ |
PRK10771 |
thiamine ABC transporter ATP-binding protein ThiQ; |
1-218 |
2.17e-34 |
|
thiamine ABC transporter ATP-binding protein ThiQ;
Pssm-ID: 182716 [Multi-domain] Cd Length: 232 Bit Score: 122.77 E-value: 2.17e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 1 MIKMTNV---YKEYPngMKaiagLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTietlaERDVPYF 77
Cdd:PRK10771 1 MLKLTDItwlYHHLP--MR----FDLTVERGERVAILGPSGAGKSTLLNLIAGFLTPASGSLTLNGQD-----HTTTPPS 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 78 RRQLGVIFQDFKLLPKLTVYENVSFALEVIEEEPDAIRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIVNRPK 157
Cdd:PRK10771 70 RRPVSMLFQENNLFSHLTVAQNIGLGLNPGLKLNAAQREKLHAIARQMGIEDLLARLPGQLSGGQRQRVALARCLVREQP 149
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446516975 158 VVIADEPTGNLDieTAL--DIMNIFTRI-NERGTTIVMATHNADIVNTIRHRVIAIEGGKIVRD 218
Cdd:PRK10771 150 ILLLDEPFSALD--PALrqEMLTLVSQVcQERQLTLLMVSHSLEDAARIAPRSLVVADGRIAWD 211
|
|
| ABC_YhbG |
cd03218 |
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the ... |
2-215 |
2.26e-34 |
|
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the YhbG family are similar to members of the Mj1267_LivG family, which is involved in the transport of branched-chain amino acids. The genes yhbG and yhbN are located in a single operon and may function together in cell envelope during biogenesis. YhbG is the putative ATP-binding cassette component and YhbN is the putative periplasmic-binding protein. Depletion of each gene product leads to growth arrest, irreversible cell damage and loss of viability in E. coli. The YhbG homolog (NtrA) is essential in Rhizobium meliloti, a symbiotic nitrogen-fixing bacterium.
Pssm-ID: 213185 [Multi-domain] Cd Length: 232 Bit Score: 122.65 E-value: 2.26e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 2 IKMTNVYKEYpNGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLaerdvPYFRR-Q 80
Cdd:cd03218 1 LRAENLSKRY-GKRKVVNGVSLSVKQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGKILLDGQDITKL-----PMHKRaR 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 81 LGVIF--QDFKLLPKLTVYENVSFALEVIEEEPDAIRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIVNRPKV 158
Cdd:cd03218 75 LGIGYlpQEASIFRKLTVEENILAVLEIRGLSKKEREEKLEELLEEFHITHLRKSKASSLSGGERRRVEIARALATNPKF 154
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 446516975 159 VIADEPTGNLDIETALDIMNIFTRINERGTTIVMATHNADIVNTIRHRVIAIEGGKI 215
Cdd:cd03218 155 LLLDEPFAGVDPIAVQDIQKIIKILKDRGIGVLITDHNVRETLSITDRAYIIYEGKV 211
|
|
| LivF |
COG0410 |
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid ... |
14-218 |
3.53e-34 |
|
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid transport and metabolism];
Pssm-ID: 440179 [Multi-domain] Cd Length: 236 Bit Score: 122.01 E-value: 3.53e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 14 GMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLAerdvPYFRRQLGVIF--QDFKLL 91
Cdd:COG0410 15 GIHVLHGVSLEVEEGEIVALLGRNGAGKTTLLKAISGLLPPRSGSIRFDGEDITGLP----PHRIARLGIGYvpEGRRIF 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 92 PKLTVYENvsfaLEV---IEEEPDAIRERVTEVLGL--VgLEDRADALPSELSGGEQQRVAIARAIVNRPKVVIADEPT- 165
Cdd:COG0410 91 PSLTVEEN----LLLgayARRDRAEVRADLERVYELfpR-LKERRRQRAGTLSGGEQQMLAIGRALMSRPKLLLLDEPSl 165
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 446516975 166 GnldietaL------DIMNIFTRINERGTTIVMATHNADIVNTIRHRVIAIEGGKIVRD 218
Cdd:COG0410 166 G-------LapliveEIFEIIRRLNREGVTILLVEQNARFALEIADRAYVLERGRIVLE 217
|
|
| cbiO |
PRK13650 |
energy-coupling factor transporter ATPase; |
20-215 |
4.46e-34 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184209 [Multi-domain] Cd Length: 279 Bit Score: 122.92 E-value: 4.46e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 20 GLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGltiETLAERDVPYFRRQLGVIFQDfkllPK-----L 94
Cdd:PRK13650 25 DVSFHVKQGEWLSIIGHNGSGKSTTVRLIDGLLEAESGQIIIDG---DLLTEENVWDIRHKIGMVFQN----PDnqfvgA 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 95 TVYENVSFALEVIEEEPDAIRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIVNRPKVVIADEPTGNLDIETAL 174
Cdd:PRK13650 98 TVEDDVAFGLENKGIPHEEMKERVNEALELVGMQDFKEREPARLSGGQKQRVAIAGAVAMRPKIIILDEATSMLDPEGRL 177
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 446516975 175 DIMNIFTRINER-GTTIVMATHNADIVnTIRHRVIAIEGGKI 215
Cdd:PRK13650 178 ELIKTIKGIRDDyQMTVISITHDLDEV-ALSDRVLVMKNGQV 218
|
|
| cbiO |
PRK13644 |
energy-coupling factor transporter ATPase; |
1-216 |
6.94e-34 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 106587 [Multi-domain] Cd Length: 274 Bit Score: 122.40 E-value: 6.94e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 1 MIKMTNVYKEYPNGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGltIETLAERDVPYFRRQ 80
Cdd:PRK13644 1 MIRLENVSYSYPDGTPALENINLVIKKGEYIGIIGKNGSGKSTLALHLNGLLRPQKGKVLVSG--IDTGDFSKLQGIRKL 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 81 LGVIFQDfkllPKL-----TVYENVSFALEVIEEEPDAIRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIVNR 155
Cdd:PRK13644 79 VGIVFQN----PETqfvgrTVEEDLAFGPENLCLPPIEIRKRVDRALAEIGLEKYRHRSPKTLSGGQGQCVALAGILTME 154
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446516975 156 PKVVIADEPTGNLDIETALDIMNIFTRINERGTTIVMATHNADIVNtIRHRVIAIEGGKIV 216
Cdd:PRK13644 155 PECLIFDEVTSMLDPDSGIAVLERIKKLHEKGKTIVYITHNLEELH-DADRIIVMDRGKIV 214
|
|
| ABC_NatA_like |
cd03267 |
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; ... |
17-218 |
6.45e-33 |
|
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled to proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of the single ATP-binding protein and the single integral membrane protein.
Pssm-ID: 213234 [Multi-domain] Cd Length: 236 Bit Score: 118.97 E-value: 6.45e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 17 AIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLtietlaerdVPY-----FRRQLGVIF-QDFKL 90
Cdd:cd03267 36 ALKGISFTIEKGEIVGFIGPNGAGKTTTLKILSGLLQPTSGEVRVAGL---------VPWkrrkkFLRRIGVVFgQKTQL 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 91 LPKLTVYENVSFALEVIEEEPDAIRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIVNRPKVVIADEPTGNLDI 170
Cdd:cd03267 107 WWDLPVIDSFYLLAAIYDLPPARFKKRLDELSELLDLEELLDTPVRQLSLGQRMRAEIAAALLHEPEILFLDEPTIGLDV 186
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 446516975 171 ETALDIMNIFTRIN-ERGTTIVMATHNADIVNTIRHRVIAIEGGKIVRD 218
Cdd:cd03267 187 VAQENIRNFLKEYNrERGTTVLLTSHYMKDIEALARRVLVIDKGRLLYD 235
|
|
| PhnL |
COG4778 |
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion ... |
1-213 |
8.36e-33 |
|
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion transport and metabolism];
Pssm-ID: 443809 [Multi-domain] Cd Length: 229 Bit Score: 118.31 E-value: 8.36e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 1 MIKMTNVYKEYP----NGMK--AIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVN----GLTIETLA 70
Cdd:COG4778 4 LLEVENLSKTFTlhlqGGKRlpVLDGVSFSVAAGECVALTGPSGAGKSTLLKCIYGNYLPDSGSILVRhdggWVDLAQAS 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 71 ERDVPYFRRQ-LGVIFQDFKLLPKLTVYENVSFALEVIEEEPDAIRERVTEVLGLVGLEDR-ADALPSELSGGEQQRVAI 148
Cdd:COG4778 84 PREILALRRRtIGYVSQFLRVIPRVSALDVVAEPLLERGVDREEARARARELLARLNLPERlWDLPPATFSGGEQQRVNI 163
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446516975 149 ARAIVNRPKVVIADEPTGNLDI---ETALDIMNiftRINERGTTIVMATHNADIVNTIRHRVIAIEGG 213
Cdd:COG4778 164 ARGFIADPPLLLLDEPTASLDAanrAVVVELIE---EAKARGTAIIGIFHDEEVREAVADRVVDVTPF 228
|
|
| 3a0107s01c2 |
TIGR00972 |
phosphate ABC transporter, ATP-binding protein; This model represents the ATP-binding protein ... |
2-196 |
9.02e-33 |
|
phosphate ABC transporter, ATP-binding protein; This model represents the ATP-binding protein of a family of ABC transporters for inorganic phosphate. In the model species Escherichia coli, a constitutive transporter for inorganic phosphate, with low affinity, is also present. The high affinity transporter that includes this polypeptide is induced when extracellular phosphate concentrations are low. The proteins most similar to the members of this family but not included appear to be amino acid transporters. [Transport and binding proteins, Anions]
Pssm-ID: 273372 [Multi-domain] Cd Length: 247 Bit Score: 118.94 E-value: 9.02e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 2 IKMTNVYKEYpNGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYR-----EEKPSTGSINVNGLTIeTLAERDVPY 76
Cdd:TIGR00972 2 IEIENLNLFY-GEKEALKNINLDIPKNQVTALIGPSGCGKSTLLRSLNRmndlvPGVRIEGKVLFDGQDI-YDKKIDVVE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 77 FRRQLGVIFQDFKLLPKlTVYENVSFALEVIEEEPDA-IRERVTEVLGLVGL----EDRADALPSELSGGEQQRVAIARA 151
Cdd:TIGR00972 80 LRRRVGMVFQKPNPFPM-SIYDNIAYGPRLHGIKDKKeLDEIVEESLKKAALwdevKDRLHDSALGLSGGQQQRLCIARA 158
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 446516975 152 IVNRPKVVIADEPTGNLDIETALDIMNIFTRINERgTTIVMATHN 196
Cdd:TIGR00972 159 LAVEPEVLLLDEPTSALDPIATGKIEELIQELKKK-YTIVIVTHN 202
|
|
| cbiO |
PRK13636 |
cobalt transporter ATP-binding subunit; Provisional |
1-216 |
1.00e-32 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184196 [Multi-domain] Cd Length: 283 Bit Score: 119.57 E-value: 1.00e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 1 MIKMTNVYKEYPNGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIEtLAERDVPYFRRQ 80
Cdd:PRK13636 5 ILKVEELNYNYSDGTHALKGININIKKGEVTAILGGNGAGKSTLFQNLNGILKPSSGRILFDGKPID-YSRKGLMKLRES 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 81 LGVIFQD-FKLLPKLTVYENVSFALEVIEEEPDAIRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIVNRPKVV 159
Cdd:PRK13636 84 VGMVFQDpDNQLFSASVYQDVSFGAVNLKLPEDEVRKRVDNALKRTGIEHLKDKPTHCLSFGQKKRVAIAGVLVMEPKVL 163
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 446516975 160 IADEPTGNLDIETALDIMNIFTRI-NERGTTIVMATHNADIVNTIRHRVIAIEGGKIV 216
Cdd:PRK13636 164 VLDEPTAGLDPMGVSEIMKLLVEMqKELGLTIIIATHDIDIVPLYCDNVFVMKEGRVI 221
|
|
| ABCC_MsbA |
cd03251 |
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; ... |
6-216 |
2.20e-32 |
|
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; MsbA is an essential ABC transporter, closely related to eukaryotic MDR proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213218 [Multi-domain] Cd Length: 234 Bit Score: 117.33 E-value: 2.20e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 6 NVYKEYPN-GMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIetlaeRDVPY--FRRQLG 82
Cdd:cd03251 5 NVTFRYPGdGPPVLRDISLDIPAGETVALVGPSGSGKSTLVNLIPRFYDVDSGRILIDGHDV-----RDYTLasLRRQIG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 83 VIFQDFKLLPKlTVYENVSFALevieeePDAIRERVTEVLGLVGLEDRADALP-----------SELSGGEQQRVAIARA 151
Cdd:cd03251 80 LVSQDVFLFND-TVAENIAYGR------PGATREEVEEAARAANAHEFIMELPegydtvigergVKLSGGQRQRIAIARA 152
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446516975 152 IVNRPKVVIADEPTGNLDIETALDIMNIFTRINERGTTIVMAtHNadiVNTIRH--RVIAIEGGKIV 216
Cdd:cd03251 153 LLKDPPILILDEATSALDTESERLVQAALERLMKNRTTFVIA-HR---LSTIENadRIVVLEDGKIV 215
|
|
| tauB |
PRK11248 |
taurine ABC transporter ATP-binding subunit; |
1-199 |
3.57e-32 |
|
taurine ABC transporter ATP-binding subunit;
Pssm-ID: 183056 [Multi-domain] Cd Length: 255 Bit Score: 117.49 E-value: 3.57e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 1 MIKMTNVYKEYPnGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETL-AERdvpyfrr 79
Cdd:PRK11248 1 MLQISHLYADYG-GKPALEDINLTLESGELLVVLGPSGCGKTTLLNLIAGFVPYQHGSITLDGKPVEGPgAER------- 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 80 qlGVIFQDFKLLPKLTVYENVSFALEVIEEEPDAIRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIVNRPKVV 159
Cdd:PRK11248 73 --GVVFQNEGLLPWRNVQDNVAFGLQLAGVEKMQRLEIAHQMLKKVGLEGAEKRYIWQLSGGQRQRVGIARALAANPQLL 150
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 446516975 160 IADEPTGNLDIETALDIMNIFTRI-NERGTTIVMATHnaDI 199
Cdd:PRK11248 151 LLDEPFGALDAFTREQMQTLLLKLwQETGKQVLLITH--DI 189
|
|
| PhnK |
COG1101 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
1-218 |
3.82e-32 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 440718 [Multi-domain] Cd Length: 264 Bit Score: 117.49 E-value: 3.82e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 1 MIKMTNVYK----EYPNGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLAErdvpY 76
Cdd:COG1101 1 MLELKNLSKtfnpGTVNEKRALDGLNLTIEEGDFVTVIGSNGAGKSTLLNAIAGSLPPDSGSILIDGKDVTKLPE----Y 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 77 FR-RQLGVIFQDFKL--LPKLTVYENVSFALE----------VIEEEPDAIRERVtEVLGLvGLEDRADALPSELSGGEQ 143
Cdd:COG1101 77 KRaKYIGRVFQDPMMgtAPSMTIEENLALAYRrgkrrglrrgLTKKRRELFRELL-ATLGL-GLENRLDTKVGLLSGGQR 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 144 QRVAIARAIVNRPKVVIADEPTGNLDIETALDIMNIfTR--INERGTTIVMATHNadivntIRH------RVIAIEGGKI 215
Cdd:COG1101 155 QALSLLMATLTKPKLLLLDEHTAALDPKTAALVLEL-TEkiVEENNLTTLMVTHN------MEQaldygnRLIMMHEGRI 227
|
...
gi 446516975 216 VRD 218
Cdd:COG1101 228 ILD 230
|
|
| ABC_BcrA_bacitracin_resist |
cd03268 |
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily ... |
2-216 |
4.69e-32 |
|
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily represents ABC transporters involved in peptide antibiotic resistance. Bacitracin is a dodecapeptide antibiotic produced by B. licheniformis and B. subtilis. The synthesis of bacitracin is non-ribosomally catalyzed by a multi-enzyme complex BcrABC. Bacitracin has potent antibiotic activity against gram-positive bacteria. The inhibition of peptidoglycan biosynthesis is the best characterized bacterial effect of bacitracin. The bacitracin resistance of B. licheniformis is mediated by the ABC transporter Bcr which is composed of two identical BcrA ATP-binding subunits and one each of the integral membrane proteins, BcrB and BcrC. B. subtilis cells carrying bcr genes on high-copy number plasmids develop collateral detergent sensitivity, a similar phenomenon in human cells with overexpressed multi-drug resistance P-glycoprotein.
Pssm-ID: 213235 [Multi-domain] Cd Length: 208 Bit Score: 115.78 E-value: 4.69e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 2 IKMTNVYKEYpNGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLAERdvpyfRRQL 81
Cdd:cd03268 1 LKTNDLTKTY-GKKRVLDDISLHVKKGEIYGFLGPNGAGKTTTMKIILGLIKPDSGEITFDGKSYQKNIEA-----LRRI 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 82 GVIFQDFKLLPKLTVYENvsfaLEVIEEEPDAIRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIVNRPKVVIA 161
Cdd:cd03268 75 GALIEAPGFYPNLTAREN----LRLLARLLGIRKKRIDEVLDVVGLKDSAKKKVKGFSLGMKQRLGIALALLGNPDLLIL 150
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 446516975 162 DEPTGNLDIETALDIMNIFTRINERGTTIVMATHNADIVNTIRHRVIAIEGGKIV 216
Cdd:cd03268 151 DEPTNGLDPDGIKELRELILSLRDQGITVLISSHLLSEIQKVADRIGIINKGKLI 205
|
|
| ABC_cobalt_CbiO_domain2 |
cd03226 |
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of ... |
6-216 |
6.14e-32 |
|
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. The CbiMNQO family ABC transport system is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.
Pssm-ID: 213193 [Multi-domain] Cd Length: 205 Bit Score: 115.43 E-value: 6.14e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 6 NVYKEYPNGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLAERDVPYF-----RRQ 80
Cdd:cd03226 4 NISFSYKKGTEILDDLSLDLYAGEIIALTGKNGAGKTTLAKILAGLIKESSGSILLNGKPIKAKERRKSIGYvmqdvDYQ 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 81 LgviFQDfkllpklTVYENVSFALEvieeEPDAIRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIVNRPKVVI 160
Cdd:cd03226 84 L---FTD-------SVREELLLGLK----ELDAGNEQAETVLKDLDLYALKERHPLSLSGGQKQRLAIAAALLSGKDLLI 149
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 446516975 161 ADEPTGNLDIETALDIMNIFTRINERGTTIVMATHNADIVNTIRHRVIAIEGGKIV 216
Cdd:cd03226 150 FDEPTSGLDYKNMERVGELIRELAAQGKAVIVITHDYEFLAKVCDRVLLLANGAIV 205
|
|
| ABCG_EPDR |
cd03213 |
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette ... |
25-195 |
1.37e-31 |
|
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily; ABCG transporters are involved in eye pigment (EP) precursor transport, regulation of lipid-trafficking mechanisms, and pleiotropic drug resistance (DR). DR is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. Compared to other members of the ABC transporter subfamilies, the ABCG transporter family is composed of proteins that have an ATP-binding cassette domain at the N-terminus and a TM (transmembrane) domain at the C-terminus.
Pssm-ID: 213180 [Multi-domain] Cd Length: 194 Bit Score: 114.19 E-value: 1.37e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 25 IKQGEFVYVVGPSGAGKSTFIK--MMYREEKPSTGSINVNGLTIETLAerdvpyFRRQLGVIFQDFKLLPKLTVYENVSF 102
Cdd:cd03213 32 AKPGELTAIMGPSGAGKSTLLNalAGRRTGLGVSGEVLINGRPLDKRS------FRKIIGYVPQDDILHPTLTVRETLMF 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 103 AlevieeepdairervtevlglvgledradALPSELSGGEQQRVAIARAIVNRPKVVIADEPTGNLDIETALDIMNIFTR 182
Cdd:cd03213 106 A-----------------------------AKLRGLSGGERKRVSIALELVSNPSLLFLDEPTSGLDSSSALQVMSLLRR 156
|
170
....*....|...
gi 446516975 183 INERGTTIVMATH 195
Cdd:cd03213 157 LADTGRTIICSIH 169
|
|
| ABC_putative_ATPase |
cd03269 |
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the ... |
2-216 |
1.67e-31 |
|
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the subfamily A transporters involved in drug resistance, nodulation, lipid transport, and bacteriocin and lantibiotic immunity. In eubacteria and archaea, the typical organization consists of one ABC and one or two integral membranes. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213236 [Multi-domain] Cd Length: 210 Bit Score: 114.30 E-value: 1.67e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 2 IKMTNVYKEYPNgMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLAERDVPYFRRQL 81
Cdd:cd03269 1 LEVENVTKRFGR-VTALDDISFSVEKGEIFGLLGPNGAGKTTTIRMILGIILPDSGEVLFDGKPLDIAARNRIGYLPEER 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 82 GvifqdfkLLPKLTVYENVSFALEVIEEEPDAIRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIVNRPKVVIA 161
Cdd:cd03269 80 G-------LYPKMKVIDQLVYLAQLKGLKKEEARRRIDEWLERLELSEYANKRVEELSKGNQQKVQFIAAVIHDPELLIL 152
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 446516975 162 DEPTGNLDIETALDIMNIFTRINERGTTIVMATHNADIVNTIRHRVIAIEGGKIV 216
Cdd:cd03269 153 DEPFSGLDPVNVELLKDVIRELARAGKTVILSTHQMELVEELCDRVLLLNKGRAV 207
|
|
| SapF |
COG4167 |
ABC-type antimicrobial peptide export system, ATPase component SapF [Defense mechanisms]; |
2-216 |
1.88e-31 |
|
ABC-type antimicrobial peptide export system, ATPase component SapF [Defense mechanisms];
Pssm-ID: 443328 [Multi-domain] Cd Length: 265 Bit Score: 115.70 E-value: 1.88e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 2 IKMTNVYKEYPNG--------MKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGltiETLAERD 73
Cdd:COG4167 5 LEVRNLSKTFKYRtglfrrqqFEAVKPVSFTLEAGQTLAIIGENGSGKSTLAKMLAGIIEPTSGEILING---HKLEYGD 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 74 VPYFRRQLGVIFQDFK--LLPKLTVYEnvsfalevIEEEP-------DAI--RERVTEVLGLVGL-EDRADALPSELSGG 141
Cdd:COG4167 82 YKYRCKHIRMIFQDPNtsLNPRLNIGQ--------ILEEPlrlntdlTAEerEERIFATLRLVGLlPEHANFYPHMLSSG 153
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446516975 142 EQQRVAIARAIVNRPKVVIADEPTGNLDIETALDIMNIFTRINER-GTTIVMATHNADIVNTIRHRVIAIEGGKIV 216
Cdd:COG4167 154 QKQRVALARALILQPKIIIADEALAALDMSVRSQIINLMLELQEKlGISYIYVSQHLGIVKHISDKVLVMHQGEVV 229
|
|
| CydC |
TIGR02868 |
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family ... |
11-196 |
2.13e-31 |
|
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex.
Pssm-ID: 274331 [Multi-domain] Cd Length: 530 Bit Score: 120.16 E-value: 2.13e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 11 YPNGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLAERDVpyfRRQLGVIFQDFKL 90
Cdd:TIGR02868 344 YPGAPPVLDGVSLDLPPGERVAILGPSGSGKSTLLATLAGLLDPLQGEVTLDGVPVSSLDQDEV---RRRVSVCAQDAHL 420
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 91 LPKlTVYENVSFAlevieeEPDAIRERVTEVLGLVGLEDRADALP-----------SELSGGEQQRVAIARAIVNRPKVV 159
Cdd:TIGR02868 421 FDT-TVRENLRLA------RPDATDEELWAALERVGLADWLRALPdgldtvlgeggARLSGGERQRLALARALLADAPIL 493
|
170 180 190
....*....|....*....|....*....|....*..
gi 446516975 160 IADEPTGNLDIETALDIMNIFtRINERGTTIVMATHN 196
Cdd:TIGR02868 494 LLDEPTEHLDAETADELLEDL-LAALSGRTVVLITHH 529
|
|
| cbiO |
PRK13641 |
energy-coupling factor transporter ATPase; |
2-217 |
2.61e-31 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237456 [Multi-domain] Cd Length: 287 Bit Score: 116.08 E-value: 2.61e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 2 IKMTNVYKEYPNGM----KAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTI--ETlAERDVP 75
Cdd:PRK13641 3 IKFENVDYIYSPGTpmekKGLDNISFELEEGSFVALVGHTGSGKSTLMQHFNALLKPSSGTITIAGYHItpET-GNKNLK 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 76 YFRRQLGVIFQdfklLPKLTVYENVsfALEVIEEEP-------DAIRERVTEVLGLVGL-EDRADALPSELSGGEQQRVA 147
Cdd:PRK13641 82 KLRKKVSLVFQ----FPEAQLFENT--VLKDVEFGPknfgfseDEAKEKALKWLKKVGLsEDLISKSPFELSGGQMRRVA 155
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 148 IARAIVNRPKVVIADEPTGNLDIETALDIMNIFTRINERGTTIVMATHNADIVNTIRHRVIAIEGGKIVR 217
Cdd:PRK13641 156 IAGVMAYEPEILCLDEPAAGLDPEGRKEMMQLFKDYQKAGHTVILVTHNMDDVAEYADDVLVLEHGKLIK 225
|
|
| YejF |
COG4172 |
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ... |
17-216 |
2.89e-31 |
|
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 443332 [Multi-domain] Cd Length: 533 Bit Score: 119.79 E-value: 2.89e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 17 AIAGLTVNIKQGEFVYVVGPSGAGKS-TFIKMM----YREEKPStGSINVNGLTIETLAERDVPYFR-RQLGVIFQD--F 88
Cdd:COG4172 25 AVKGVSFDIAAGETLALVGESGSGKSvTALSILrllpDPAAHPS-GSILFDGQDLLGLSERELRRIRgNRIAMIFQEpmT 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 89 KLLPKLTVYENVSfalEVIEE----EPDAIRERVTEVLGLVGL---EDRADALPSELSGGEQQRVAIARAIVNRPKVVIA 161
Cdd:COG4172 104 SLNPLHTIGKQIA---EVLRLhrglSGAAARARALELLERVGIpdpERRLDAYPHQLSGGQRQRVMIAMALANEPDLLIA 180
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446516975 162 DEPTgnldieTALD------IMNIFTRI-NERGTTIVMATHNADIVNTIRHRVIAIEGGKIV 216
Cdd:COG4172 181 DEPT------TALDvtvqaqILDLLKDLqRELGMALLLITHDLGVVRRFADRVAVMRQGEIV 236
|
|
| modC_ABC |
TIGR02142 |
molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding ... |
35-215 |
3.08e-31 |
|
molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding cassette (ABC) protein of the three subunit molybdate ABC transporter. The three proteins of this complex are homologous to proteins of the sulfate ABC transporter. Molybdenum may be used in nitrogenases of nitrogen-fixing bacteria and in molybdopterin cofactors. In some cases, molybdate may be transported by a sulfate transporter rather than by a specific molybdate transporter. [Transport and binding proteins, Anions]
Pssm-ID: 131197 [Multi-domain] Cd Length: 354 Bit Score: 117.14 E-value: 3.08e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 35 GPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLAER-DVPYFRRQLGVIFQDFKLLPKLTVYENVSFALEVIEEEPDA 113
Cdd:TIGR02142 30 GRSGSGKTTLIRLIAGLTRPDEGEIVLNGRTLFDSRKGiFLPPEKRRIGYVFQEARLFPHLSVRGNLRYGMKRARPSERR 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 114 IR-ERVTEVLGLVGLEDRadaLPSELSGGEQQRVAIARAIVNRPKVVIADEPTGNLDIETALDIMNIFTRIN-ERGTTIV 191
Cdd:TIGR02142 110 ISfERVIELLGIGHLLGR---LPGRLSGGEKQRVAIGRALLSSPRLLLMDEPLAALDDPRKYEILPYLERLHaEFGIPIL 186
|
170 180
....*....|....*....|....
gi 446516975 192 MATHNADIVNTIRHRVIAIEGGKI 215
Cdd:TIGR02142 187 YVSHSLQEVLRLADRVVVLEDGRV 210
|
|
| MglA |
COG1129 |
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; |
1-195 |
3.67e-31 |
|
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440745 [Multi-domain] Cd Length: 497 Bit Score: 118.97 E-value: 3.67e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 1 MIKMTNVYKEYPnGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLAERDVpyfrRQ 80
Cdd:COG1129 4 LLEMRGISKSFG-GVKALDGVSLELRPGEVHALLGENGAGKSTLMKILSGVYQPDSGEILLDGEPVRFRSPRDA----QA 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 81 LGV--IFQDFKLLPKLTVYENVsfaleVIEEEP--------DAIRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIAR 150
Cdd:COG1129 79 AGIaiIHQELNLVPNLSVAENI-----FLGREPrrgglidwRAMRRRARELLARLGLDIDPDTPVGDLSVAQQQLVEIAR 153
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 446516975 151 AIVNRPKVVIADEPTGNL---DIETALDIMNiftRINERGTTIVMATH 195
Cdd:COG1129 154 ALSRDARVLILDEPTASLterEVERLFRIIR---RLKAQGVAIIYISH 198
|
|
| CeuD |
COG4604 |
ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and ... |
1-220 |
4.90e-31 |
|
ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443654 [Multi-domain] Cd Length: 252 Bit Score: 114.41 E-value: 4.90e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 1 MIKMTNVYKEYpNGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLAERDVPyfrRQ 80
Cdd:COG4604 1 MIEIKNVSKRY-GGKVVLDDVSLTIPKGGITALIGPNGAGKSTLLSMISRLLPPDSGEVLVDGLDVATTPSRELA---KR 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 81 LGVIFQDFKLLPKLTVYENVSF--------ALEVIEeepdaiRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAI 152
Cdd:COG4604 77 LAILRQENHINSRLTVRELVAFgrfpyskgRLTAED------REIIDEAIAYLDLEDLADRYLDELSGGQRQRAFIAMVL 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 153 VNRPKVVIADEPTGNLDIETALDIMNIFTRI-NERGTTIVM-------ATHNADivntirhRVIAIEGGKIVR----DEI 220
Cdd:COG4604 151 AQDTDYVLLDEPLNNLDMKHSVQMMKLLRRLaDELGKTVVIvlhdinfASCYAD-------HIVAMKDGRVVAqgtpEEI 223
|
|
| PstB |
COG1117 |
ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism]; ... |
16-196 |
8.59e-31 |
|
ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440734 [Multi-domain] Cd Length: 258 Bit Score: 113.98 E-value: 8.59e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 16 KAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYR--EEKPS---TGSINVNGLTIETlAERDVPYFRRQLGVIFQDFKL 90
Cdd:COG1117 25 QALKDINLDIPENKVTALIGPSGCGKSTLLRCLNRmnDLIPGarvEGEILLDGEDIYD-PDVDVVELRRRVGMVFQKPNP 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 91 LPKlTVYENVSFALEVIEEEPDA-IRERVTEVLGLVGL----EDRADALPSELSGGEQQRVAIARAIVNRPKVVIADEPT 165
Cdd:COG1117 104 FPK-SIYDNVAYGLRLHGIKSKSeLDEIVEESLRKAALwdevKDRLKKSALGLSGGQQQRLCIARALAVEPEVLLMDEPT 182
|
170 180 190
....*....|....*....|....*....|....*...
gi 446516975 166 GNLD-IETAldimniftRINE-----RGT-TIVMATHN 196
Cdd:COG1117 183 SALDpISTA--------KIEElilelKKDyTIVIVTHN 212
|
|
| ABCC_Protease_Secretion |
cd03246 |
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of ... |
2-215 |
1.73e-30 |
|
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of the protease secretion system PrtD, a 60-kDa integral membrane protein sharing 37% identity with HlyB, the ABC component of the alpha-hemolysin secretion pathway, in the C-terminal domain. They export degradative enzymes by using a type I protein secretion system and lack an N-terminal signal peptide, but contain a C-terminal secretion signal. The Type I secretion apparatus is made up of three components, an ABC transporter, a membrane fusion protein (MFP), and an outer membrane protein (OMP). For the HlyA transporter complex, HlyB (ABC transporter) and HlyD (MFP) reside in the inner membrane of E. coli. The OMP component is TolC, which is thought to interact with the MFP to form a continuous channel across the periplasm from the cytoplasm to the exterior. HlyB belongs to the family of ABC transporters, which are ubiquitous, ATP-dependent transmembrane pumps or channels. The spectrum of transport substrates ranges from inorganic ions, nutrients such as amino acids, sugars, or peptides, hydrophobic drugs, to large polypeptides, such as HlyA.
Pssm-ID: 213213 [Multi-domain] Cd Length: 173 Bit Score: 110.77 E-value: 1.73e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 2 IKMTNVYKEYPNGMKAI-AGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLAERDvpyFRRQ 80
Cdd:cd03246 1 LEVENVSFRYPGAEPPVlRNVSFSIEPGESLAIIGPSGSGKSTLARLILGLLRPTSGRVRLDGADISQWDPNE---LGDH 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 81 LGVIFQDFKLLPKlTVYENVsfalevieeepdairervtevlglvgledradalpseLSGGEQQRVAIARAIVNRPKVVI 160
Cdd:cd03246 78 VGYLPQDDELFSG-SIAENI-------------------------------------LSGGQRQRLGLARALYGNPRILV 119
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 446516975 161 ADEPTGNLDIETALDIMNIFTRINERGTTIVMATHNADIVNTIrHRVIAIEGGKI 215
Cdd:cd03246 120 LDEPNSHLDVEGERALNQAIAALKAAGATRIVIAHRPETLASA-DRILVLEDGRV 173
|
|
| cbiO |
PRK13649 |
energy-coupling factor transporter ATPase; |
2-217 |
2.02e-30 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184208 [Multi-domain] Cd Length: 280 Bit Score: 113.69 E-value: 2.02e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 2 IKMTNVYKEYPNGM----KAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLAE-RDVPY 76
Cdd:PRK13649 3 INLQNVSYTYQAGTpfegRALFDVNLTIEDGSYTAFIGHTGSGKSTIMQLLNGLHVPTQGSVRVDDTLITSTSKnKDIKQ 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 77 FRRQLGVIFQ--DFKLLPKlTVYENVSFALE---VIEEEPDAIRErvtEVLGLVGL-EDRADALPSELSGGEQQRVAIAR 150
Cdd:PRK13649 83 IRKKVGLVFQfpESQLFEE-TVLKDVAFGPQnfgVSQEEAEALAR---EKLALVGIsESLFEKNPFELSGGQMRRVAIAG 158
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446516975 151 AIVNRPKVVIADEPTGNLDIETALDIMNIFTRINERGTTIVMATHNADIVNTIRHRVIAIEGGKIVR 217
Cdd:PRK13649 159 ILAMEPKILVLDEPTAGLDPKGRKELMTLFKKLHQSGMTIVLVTHLMDDVANYADFVYVLEKGKLVL 225
|
|
| PRK13537 |
PRK13537 |
nodulation factor ABC transporter ATP-binding protein NodI; |
2-214 |
2.07e-30 |
|
nodulation factor ABC transporter ATP-binding protein NodI;
Pssm-ID: 237420 [Multi-domain] Cd Length: 306 Bit Score: 114.13 E-value: 2.07e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 2 IKMTNVYKEYpnGMKAIA-GLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLAerdvPYFRRQ 80
Cdd:PRK13537 8 IDFRNVEKRY--GDKLVVdGLSFHVQRGECFGLLGPNGAGKTTTLRMLLGLTHPDAGSISLCGEPVPSRA----RHARQR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 81 LGVIFQDFKLLPKLTVYENVSFALEVIEEEPDAIRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIVNRPKVVI 160
Cdd:PRK13537 82 VGVVPQFDNLDPDFTVRENLLVFGRYFGLSAAAARALVPPLLEFAKLENKADAKVGELSGGMKRRLTLARALVNDPDVLV 161
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 446516975 161 ADEPTGNLDIETALDIMNIFTRINERGTTIVMATHNADIVNTIRHRVIAIEGGK 214
Cdd:PRK13537 162 LDEPTTGLDPQARHLMWERLRSLLARGKTILLTTHFMEEAERLCDRLCVIEEGR 215
|
|
| ABCG_White |
cd03234 |
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ... |
9-216 |
3.99e-30 |
|
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ABC transporters homologous to the Drosophila white gene, which acts as a dimeric importer for eye pigment precursors. The eye pigmentation of Drosophila is developed from the synthesis and deposition in the cells of red pigments, which are synthesized from guanine, and brown pigments, which are synthesized from tryptophan. The pigment precursors are encoded by the white, brown, and scarlet genes, respectively. Evidence from genetic and biochemical studies suggest that the White and Brown proteins function as heterodimers to import guanine, while the White and Scarlet proteins function to import tryptophan. However, a recent study also suggests that White may be involved in the transport of a metabolite, such as 3-hydroxykynurenine, across intracellular membranes. Mammalian ABC transporters belonging to the White subfamily (ABCG1, ABCG5, and ABCG8) have been shown to be involved in the regulation of lipid-trafficking mechanisms in macrophages, hepatocytes, and intestinal mucosa cells. ABCG1 (ABC8), the human homolog of the Drosophila white gene is induced in monocyte-derived macrophages during cholesterol influx mediated by acetylated low-density lipoprotein. It is possible that human ABCG1 forms heterodimers with several heterologous partners.
Pssm-ID: 213201 [Multi-domain] Cd Length: 226 Bit Score: 111.21 E-value: 3.99e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 9 KEYPNGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTF---IKMMYREEKPSTGSINVNGltietlAERDVPYFRRQLGVIF 85
Cdd:cd03234 14 KNWNKYARILNDVSLHVESGQVMAILGSSGSGKTTLldaISGRVEGGGTTSGQILFNG------QPRKPDQFQKCVAYVR 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 86 QDFKLLPKLTVYENVSFA--LEVIEEEPDAIRERVTEVLGL--VGLEDRADALPSELSGGEQQRVAIARAIVNRPKVVIA 161
Cdd:cd03234 88 QDDILLPGLTVRETLTYTaiLRLPRKSSDAIRKKRVEDVLLrdLALTRIGGNLVKGISGGERRRVSIAVQLLWDPKVLIL 167
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 446516975 162 DEPTGNLDIETALDIMNIFTRINERGTTIVMATHN--ADIVNTIrHRVIAIEGGKIV 216
Cdd:cd03234 168 DEPTSGLDSFTALNLVSTLSQLARRNRIVILTIHQprSDLFRLF-DRILLLSSGEIV 223
|
|
| MsbA_lipidA |
TIGR02203 |
lipid A export permease/ATP-binding protein MsbA; This family consists of a single polypeptide ... |
2-216 |
4.07e-30 |
|
lipid A export permease/ATP-binding protein MsbA; This family consists of a single polypeptide chain transporter in the ATP-binding cassette (ABC) transporter family, MsbA, which exports lipid A. It may also act in multidrug resistance. Lipid A, a part of lipopolysaccharide, is found in the outer leaflet of the outer membrane of most Gram-negative bacteria. Members of this family are restricted to the Proteobacteria (although lipid A is more broadly distributed) and often are clustered with lipid A biosynthesis genes. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides, Transport and binding proteins, Other]
Pssm-ID: 131258 [Multi-domain] Cd Length: 571 Bit Score: 116.74 E-value: 4.07e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 2 IKMTNVYKEYP-NGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLAERDVpyfRRQ 80
Cdd:TIGR02203 331 VEFRNVTFRYPgRDRPALDSISLVIEPGETVALVGRSGSGKSTLVNLIPRFYEPDSGQILLDGHDLADYTLASL---RRQ 407
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 81 LGVIFQDFKLLPKlTVYENVSFAlevieEEPDAIRERVTEVLGLVGLEDRADALP-----------SELSGGEQQRVAIA 149
Cdd:TIGR02203 408 VALVSQDVVLFND-TIANNIAYG-----RTEQADRAEIERALAAAYAQDFVDKLPlgldtpigengVLLSGGQRQRLAIA 481
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446516975 150 RAIVNRPKVVIADEPTGNLDIETALDIMNIFTRINERGTTIVMAtHNadiVNTIRH--RVIAIEGGKIV 216
Cdd:TIGR02203 482 RALLKDAPILILDEATSALDNESERLVQAALERLMQGRTTLVIA-HR---LSTIEKadRIVVMDDGRIV 546
|
|
| PRK14247 |
PRK14247 |
phosphate ABC transporter ATP-binding protein; Provisional |
16-216 |
4.29e-30 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172735 [Multi-domain] Cd Length: 250 Bit Score: 111.93 E-value: 4.29e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 16 KAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYR-----EEKPSTGSINVNGLTIETLaerDVPYFRRQLGVIFQDFKL 90
Cdd:PRK14247 17 EVLDGVNLEIPDNTITALMGPSGSGKSTLLRVFNRlielyPEARVSGEVYLDGQDIFKM---DVIELRRRVQMVFQIPNP 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 91 LPKLTVYENVSFALEV--IEEEPDAIRERVTEVLGLVGL----EDRADALPSELSGGEQQRVAIARAIVNRPKVVIADEP 164
Cdd:PRK14247 94 IPNLSIFENVALGLKLnrLVKSKKELQERVRWALEKAQLwdevKDRLDAPAGKLSGGQQQRLCIARALAFQPEVLLADEP 173
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 446516975 165 TGNLDIETALDIMNIFTRInERGTTIVMATHNADIVNTIRHRVIAIEGGKIV 216
Cdd:PRK14247 174 TANLDPENTAKIESLFLEL-KKDMTIVLVTHFPQQAARISDYVAFLYKGQIV 224
|
|
| met_CoM_red_A2 |
TIGR03269 |
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ... |
1-217 |
4.83e-30 |
|
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]
Pssm-ID: 132313 [Multi-domain] Cd Length: 520 Bit Score: 116.44 E-value: 4.83e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 1 MIKMTNVYKEYPN----GMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVN------GLTIETLA 70
Cdd:TIGR03269 279 IIKVRNVSKRYISvdrgVVKAVDNVSLEVKEGEIFGIVGTSGAGKTTLSKIIAGVLEPTSGEVNVRvgdewvDMTKPGPD 358
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 71 ERDVPyfRRQLGVIFQDFKLLPKLTVYENVSFALEVieEEPDAI-RERVTEVLGLVGLEDRA-----DALPSELSGGEQQ 144
Cdd:TIGR03269 359 GRGRA--KRYIGILHQEYDLYPHRTVLDNLTEAIGL--ELPDELaRMKAVITLKMVGFDEEKaeeilDKYPDELSEGERH 434
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446516975 145 RVAIARAIVNRPKVVIADEPTGNLDIETALDIMN-IFTRINERGTTIVMATHNADIVNTIRHRVIAIEGGKIVR 217
Cdd:TIGR03269 435 RVALAQVLIKEPRIVILDEPTGTMDPITKVDVTHsILKAREEMEQTFIIVSHDMDFVLDVCDRAALMRDGKIVK 508
|
|
| cbiO |
PRK13645 |
energy-coupling factor transporter ATPase; |
9-216 |
4.95e-30 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184204 [Multi-domain] Cd Length: 289 Bit Score: 112.79 E-value: 4.95e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 9 KEYPNGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLAER--DVPYFRRQLGVIFQ 86
Cdd:PRK13645 18 KKTPFEFKALNNTSLTFKKNKVTCVIGTTGSGKSTMIQLTNGLIISETGQTIVGDYAIPANLKKikEVKRLRKEIGLVFQ 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 87 --DFKLLPKlTVYENVSFALEVIEEEPDAIRERVTEVLGLVGL-EDRADALPSELSGGEQQRVAIARAIVNRPKVVIADE 163
Cdd:PRK13645 98 fpEYQLFQE-TIEKDIAFGPVNLGENKQEAYKKVPELLKLVQLpEDYVKRSPFELSGGQKRRVALAGIIAMDGNTLVLDE 176
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 446516975 164 PTGNLDIETALDIMNIFTRIN-ERGTTIVMATHNADIVNTIRHRVIAIEGGKIV 216
Cdd:PRK13645 177 PTGGLDPKGEEDFINLFERLNkEYKKRIIMVTHNMDQVLRIADEVIVMHEGKVI 230
|
|
| COG4559 |
COG4559 |
ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism]; |
18-216 |
1.17e-29 |
|
ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443620 [Multi-domain] Cd Length: 258 Bit Score: 110.98 E-value: 1.17e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 18 IAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLAERDVPyfrRQLGVIFQDFKL-LPkLTV 96
Cdd:COG4559 17 LDDVSLTLRPGELTAIIGPNGAGKSTLLKLLTGELTPSSGEVRLNGRPLAAWSPWELA---RRRAVLPQHSSLaFP-FTV 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 97 YENVSFALEVIEEEPDAIRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIV-------NRPKVVIADEPTGNLD 169
Cdd:COG4559 93 EEVVALGRAPHGSSAAQDRQIVREALALVGLAHLAGRSYQTLSGGEQQRVQLARVLAqlwepvdGGPRWLFLDEPTSALD 172
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 446516975 170 IETALDIMNIFTRINERGTTIVMATH--N-----ADivntirhRVIAIEGGKIV 216
Cdd:COG4559 173 LAHQHAVLRLARQLARRGGGVVAVLHdlNlaaqyAD-------RILLLHQGRLV 219
|
|
| PRK13657 |
PRK13657 |
glucan ABC transporter ATP-binding protein/ permease; |
6-216 |
3.26e-29 |
|
glucan ABC transporter ATP-binding protein/ permease;
Pssm-ID: 184214 [Multi-domain] Cd Length: 588 Bit Score: 114.29 E-value: 3.26e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 6 NVYKEYPNGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLAERDVpyfRRQLGVIF 85
Cdd:PRK13657 339 DVSFSYDNSRQGVEDVSFEAKPGQTVAIVGPTGAGKSTLINLLQRVFDPQSGRILIDGTDIRTVTRASL---RRNIAVVF 415
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 86 QDFKLLPKlTVYENVSFAlevieeEPDAIRERVTEVLGLV-----------GLEDRADALPSELSGGEQQRVAIARAIVN 154
Cdd:PRK13657 416 QDAGLFNR-SIEDNIRVG------RPDATDEEMRAAAERAqahdfierkpdGYDTVVGERGRQLSGGERQRLAIARALLK 488
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446516975 155 RPKVVIADEPTGNLDIETALDIMNIFTRINERGTTIVMAtHNadiVNTIRH--RVIAIEGGKIV 216
Cdd:PRK13657 489 DPPILILDEATSALDVETEAKVKAALDELMKGRTTFIIA-HR---LSTVRNadRILVFDNGRVV 548
|
|
| cbiO |
PRK13634 |
cobalt transporter ATP-binding subunit; Provisional |
16-217 |
3.44e-29 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237454 [Multi-domain] Cd Length: 290 Bit Score: 110.49 E-value: 3.44e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 16 KAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIE-TLAERDVPYFRRQLGVIFQ--DFKLLP 92
Cdd:PRK13634 21 RALYDVNVSIPSGSYVAIIGHTGSGKSTLLQHLNGLLQPTSGTVTIGERVITaGKKNKKLKPLRKKVGIVFQfpEHQLFE 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 93 KlTVYENVSFA---LEVIEEEPdaiRERVTEVLGLVGL-EDRADALPSELSGGEQQRVAIARAIVNRPKVVIADEPTGNL 168
Cdd:PRK13634 101 E-TVEKDICFGpmnFGVSEEDA---KQKAREMIELVGLpEELLARSPFELSGGQMRRVAIAGVLAMEPEVLVLDEPTAGL 176
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 446516975 169 DIETALDIMNIFTRIN-ERGTTIVMATHNADIVNTIRHRVIAIEGGKIVR 217
Cdd:PRK13634 177 DPKGRKEMMEMFYKLHkEKGLTTVLVTHSMEDAARYADQIVVMHKGTVFL 226
|
|
| LPS_export_lptB |
TIGR04406 |
LPS export ABC transporter ATP-binding protein; Members of this fmaily are LptB, the ... |
2-216 |
6.62e-29 |
|
LPS export ABC transporter ATP-binding protein; Members of this fmaily are LptB, the ATP-binding cassette protein of an ABC transporter involved in lipopolysaccharide export. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides, Transport and binding proteins, Other]
Pssm-ID: 275199 [Multi-domain] Cd Length: 239 Bit Score: 108.52 E-value: 6.62e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 2 IKMTNVYKEYpNGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIetlaeRDVP-YFRRQ 80
Cdd:TIGR04406 2 LVAENLIKSY-KKRKVVNDVSLSVKSGEIVGLLGPNGAGKTTSFYMIVGLVRPDAGKILIDGQDI-----THLPmHERAR 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 81 LGVIF--QDFKLLPKLTVYENVSFALEVIEE-EPDAIRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIVNRPK 157
Cdd:TIGR04406 76 LGIGYlpQEASIFRKLTVEENIMAVLEIRKDlDRAEREERLEALLEEFQISHLRDNKAMSLSGGERRRVEIARALATNPK 155
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 446516975 158 VVIADEPTGNLDIETALDIMNIFTRINERGTTIVMATHNADIVNTIRHRVIAIEGGKIV 216
Cdd:TIGR04406 156 FILLDEPFAGVDPIAVGDIKKIIKHLKERGIGVLITDHNVRETLDICDRAYIISDGKVL 214
|
|
| cbiO |
PRK13652 |
cobalt transporter ATP-binding subunit; Provisional |
1-216 |
7.51e-29 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 172200 [Multi-domain] Cd Length: 277 Bit Score: 109.51 E-value: 7.51e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 1 MIKMTNVYKEYPNGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGltiETLAERDVPYFRRQ 80
Cdd:PRK13652 3 LIETRDLCYSYSGSKEALNNINFIAPRNSRIAVIGPNGAGKSTLFRHFNGILKPTSGSVLIRG---EPITKENIREVRKF 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 81 LGVIFQ---DFKLLPklTVYENVSFALEVIEEEPDAIRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIVNRPK 157
Cdd:PRK13652 80 VGLVFQnpdDQIFSP--TVEQDIAFGPINLGLDEETVAHRVSSALHMLGLEELRDRVPHHLSGGEKKRVAIAGVIAMEPQ 157
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 158 VVIADEPTGNLDIETALDIMNIFTRINER-GTTIVMATHNADIVNTIRHRVIAIEGGKIV 216
Cdd:PRK13652 158 VLVLDEPTAGLDPQGVKELIDFLNDLPETyGMTVIFSTHQLDLVPEMADYIYVMDKGRIV 217
|
|
| dppF |
PRK11308 |
dipeptide transporter ATP-binding subunit; Provisional |
16-216 |
7.52e-29 |
|
dipeptide transporter ATP-binding subunit; Provisional
Pssm-ID: 236898 [Multi-domain] Cd Length: 327 Bit Score: 110.44 E-value: 7.52e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 16 KAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLAERDVPYFRRQLGVIFQD--FKLLPK 93
Cdd:PRK11308 29 KALDGVSFTLERGKTLAVVGESGCGKSTLARLLTMIETPTGGELYYQGQDLLKADPEAQKLLRQKIQIVFQNpyGSLNPR 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 94 LTVyenvsfalEVIEEEPDAI---------RERVTEVLGLVGLE-DRADALPSELSGGEQQRVAIARAIVNRPKVVIADE 163
Cdd:PRK11308 109 KKV--------GQILEEPLLIntslsaaerREKALAMMAKVGLRpEHYDRYPHMFSGGQRQRIAIARALMLDPDVVVADE 180
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 446516975 164 PTGNLDIETALDIMNIFTRI-NERGTTIVMATHNADIVNTIRHRVIAIEGGKIV 216
Cdd:PRK11308 181 PVSALDVSVQAQVLNLMMDLqQELGLSYVFISHDLSVVEHIADEVMVMYLGRCV 234
|
|
| NupO |
COG3845 |
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ... |
1-216 |
7.87e-29 |
|
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];
Pssm-ID: 443055 [Multi-domain] Cd Length: 504 Bit Score: 112.81 E-value: 7.87e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 1 MIKMTNVYKEYPnGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGltietlaeRDVPyFR-- 78
Cdd:COG3845 5 ALELRGITKRFG-GVVANDDVSLTVRPGEIHALLGENGAGKSTLMKILYGLYQPDSGEILIDG--------KPVR-IRsp 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 79 ---RQLGV--IFQDFKLLPKLTVYENVSFALE---VIEEEPDAIRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIAR 150
Cdd:COG3845 75 rdaIALGIgmVHQHFMLVPNLTVAENIVLGLEptkGGRLDRKAARARIRELSERYGLDVDPDAKVEDLSVGEQQRVEILK 154
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446516975 151 AIVNRPKVVIADEPTGNLDIETALDIMNIFTRINERGTTIVMATHNADIVNTIRHRVIAIEGGKIV 216
Cdd:COG3845 155 ALYRGARILILDEPTAVLTPQEADELFEILRRLAAEGKSIIFITHKLREVMAIADRVTVLRRGKVV 220
|
|
| COG4586 |
COG4586 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
1-218 |
1.08e-28 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 443643 [Multi-domain] Cd Length: 323 Bit Score: 109.79 E-value: 1.08e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 1 MIKMTNVYKEYP-----NGMK---------------AIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMM----YreekPST 56
Cdd:COG4586 1 IIEVENLSKTYRvyekePGLKgalkglfrreyreveAVDDISFTIEPGEIVGFIGPNGAGKSTTIKMLtgilV----PTS 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 57 GSINVNGLtietlaerdVPY-----FRRQLGVIF-QDFKLLPKLTVYEnvSFAL--EVIEEEPDAIRERVTEVLGLVGLE 128
Cdd:COG4586 77 GEVRVLGY---------VPFkrrkeFARRIGVVFgQRSQLWWDLPAID--SFRLlkAIYRIPDAEYKKRLDELVELLDLG 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 129 D------RadalpsELSGGEQQRVAIARAIVNRPKVVIADEPTGNLDIETALDIMNIFTRIN-ERGTTIVMATHN-ADIV 200
Cdd:COG4586 146 ElldtpvR------QLSLGQRMRCELAAALLHRPKILFLDEPTIGLDVVSKEAIREFLKEYNrERGTTILLTSHDmDDIE 219
|
250
....*....|....*...
gi 446516975 201 NTIRhRVIAIEGGKIVRD 218
Cdd:COG4586 220 ALCD-RVIVIDHGRIIYD 236
|
|
| cbiO |
PRK13643 |
energy-coupling factor transporter ATPase; |
1-216 |
1.57e-28 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184203 [Multi-domain] Cd Length: 288 Bit Score: 108.67 E-value: 1.57e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 1 MIKMTNVYKEY----PNGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTI-ETLAERDVP 75
Cdd:PRK13643 1 MIKFEKVNYTYqpnsPFASRALFDIDLEVKKGSYTALIGHTGSGKSTLLQHLNGLLQPTEGKVTVGDIVVsSTSKQKEIK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 76 YFRRQLGVIFQ--DFKLLPKlTVYENVSFALE---VIEEEPDAIRERVTEVLGLVglEDRADALPSELSGGEQQRVAIAR 150
Cdd:PRK13643 81 PVRKKVGVVFQfpESQLFEE-TVLKDVAFGPQnfgIPKEKAEKIAAEKLEMVGLA--DEFWEKSPFELSGGQMRRVAIAG 157
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446516975 151 AIVNRPKVVIADEPTGNLDIETALDIMNIFTRINERGTTIVMATHNADIVNTIRHRVIAIEGGKIV 216
Cdd:PRK13643 158 ILAMEPEVLVLDEPTAGLDPKARIEMMQLFESIHQSGQTVVLVTHLMDDVADYADYVYLLEKGHII 223
|
|
| PRK10070 |
PRK10070 |
proline/glycine betaine ABC transporter ATP-binding protein ProV; |
22-220 |
5.56e-28 |
|
proline/glycine betaine ABC transporter ATP-binding protein ProV;
Pssm-ID: 182221 [Multi-domain] Cd Length: 400 Bit Score: 109.35 E-value: 5.56e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 22 TVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLAERDVPYFRRQ-LGVIFQDFKLLPKLTVYENV 100
Cdd:PRK10070 48 SLAIEEGEIFVIMGLSGSGKSTMVRLLNRLIEPTRGQVLIDGVDIAKISDAELREVRRKkIAMVFQSFALMPHMTVLDNT 127
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 101 SFALEVIEEEPDAIRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIVNRPKVVIADEPTGNLDIETALDIMNIF 180
Cdd:PRK10070 128 AFGMELAGINAEERREKALDALRQVGLENYAHSYPDELSGGMRQRVGLARALAINPDILLMDEAFSALDPLIRTEMQDEL 207
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 446516975 181 TRINERGT-TIVMATHNADIVNTIRHRVIAIEGGKIVR----DEI 220
Cdd:PRK10070 208 VKLQAKHQrTIVFISHDLDEAMRIGDRIAIMQNGEVVQvgtpDEI 252
|
|
| YhaQ |
COG4152 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
1-226 |
7.59e-28 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 443322 [Multi-domain] Cd Length: 298 Bit Score: 107.12 E-value: 7.59e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 1 MIKMTNVYKEYpNGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGltiETLAERDvpyfRRQ 80
Cdd:COG4152 1 MLELKGLTKRF-GDKTAVDDVSFTVPKGEIFGLLGPNGAGKTTTIRIILGILAPDSGEVLWDG---EPLDPED----RRR 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 81 LGvifqdfkLLP-------KLTVYENVSF--ALEVIEeePDAIRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARA 151
Cdd:COG4152 73 IG-------YLPeerglypKMKVGEQLVYlaRLKGLS--KAEAKRRADEWLERLGLGDRANKKVEELSKGNQQKVQLIAA 143
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446516975 152 IVNRPKVVIADEPTGNLDIETALDIMNIFTRINERGTTIVMATHNADIVNTIRHRVIAIEGGKIV----RDEIEGGYGY 226
Cdd:COG4152 144 LLHDPELLILDEPFSGLDPVNVELLKDVIRELAAKGTTVIFSSHQMELVEELCDRIVIINKGRKVlsgsVDEIRRQFGR 222
|
|
| PRK11160 |
PRK11160 |
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed |
2-216 |
7.88e-28 |
|
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
Pssm-ID: 236865 [Multi-domain] Cd Length: 574 Bit Score: 110.30 E-value: 7.88e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 2 IKMTNVYKEYPNG-MKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLAERDVpyfRRQ 80
Cdd:PRK11160 339 LTLNNVSFTYPDQpQPVLKGLSLQIKAGEKVALLGRTGCGKSTLLQLLTRAWDPQQGEILLNGQPIADYSEAAL---RQA 415
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 81 LGVIFQDFKLLPKlTVYENVSFALevieeePDAIRERVTEVLGLVGLEDRADALPS----------ELSGGEQQRVAIAR 150
Cdd:PRK11160 416 ISVVSQRVHLFSA-TLRDNLLLAA------PNASDEALIEVLQQVGLEKLLEDDKGlnawlgeggrQLSGGEQRRLGIAR 488
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 151 AIVNRPKVVIADEPTGNLDIETALDIMNIftrINE--RGTTIVMATHNAdivNTIRH--RVIAIEGGKIV 216
Cdd:PRK11160 489 ALLHDAPLLLLDEPTEGLDAETERQILEL---LAEhaQNKTVLMITHRL---TGLEQfdRICVMDNGQII 552
|
|
| PRK14246 |
PRK14246 |
phosphate ABC transporter ATP-binding protein; Provisional |
11-216 |
1.14e-27 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172734 [Multi-domain] Cd Length: 257 Bit Score: 105.90 E-value: 1.14e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 11 YPNGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTI---ETLAERDVPYFRRQLGVIFQD 87
Cdd:PRK14246 19 YINDKAILKDITIKIPNNSIFGIMGPSGSGKSTLLKVLNRLIEIYDSKIKVDGKVLyfgKDIFQIDAIKLRKEVGMVFQQ 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 88 FKLLPKLTVYENVSFALEV--IEEEPDaIRERVTEVLGLVGL----EDRADALPSELSGGEQQRVAIARAIVNRPKVVIA 161
Cdd:PRK14246 99 PNPFPHLSIYDNIAYPLKShgIKEKRE-IKKIVEECLRKVGLwkevYDRLNSPASQLSGGQQQRLTIARALALKPKVLLM 177
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 446516975 162 DEPTGNLDIETALDIMNIFTRINERgTTIVMATHNADIVNTIRHRVIAIEGGKIV 216
Cdd:PRK14246 178 DEPTSMIDIVNSQAIEKLITELKNE-IAIVIVSHNPQQVARVADYVAFLYNGELV 231
|
|
| hmuV |
PRK13548 |
hemin importer ATP-binding subunit; Provisional |
18-216 |
1.17e-27 |
|
hemin importer ATP-binding subunit; Provisional
Pssm-ID: 237422 [Multi-domain] Cd Length: 258 Bit Score: 105.62 E-value: 1.17e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 18 IAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLAERDVPyfrRQLGVIFQDFKLLPKLTVY 97
Cdd:PRK13548 18 LDDVSLTLRPGEVVAILGPNGAGKSTLLRALSGELSPDSGEVRLNGRPLADWSPAELA---RRRAVLPQHSSLSFPFTVE 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 98 ENVSFALEVIEEEPDAIRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIV------NRPKVVIADEPTGNLDIE 171
Cdd:PRK13548 95 EVVAMGRAPHGLSRAEDDALVAAALAQVDLAHLAGRDYPQLSGGEQQRVQLARVLAqlwepdGPPRWLLLDEPTSALDLA 174
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 446516975 172 TALDIMNI---FTRinERGTTIV-------MATHNADivntirhRVIAIEGGKIV 216
Cdd:PRK13548 175 HQHHVLRLarqLAH--ERGLAVIvvlhdlnLAARYAD-------RIVLLHQGRLV 220
|
|
| PRK15079 |
PRK15079 |
oligopeptide ABC transporter ATP-binding protein OppF; Provisional |
12-208 |
1.34e-27 |
|
oligopeptide ABC transporter ATP-binding protein OppF; Provisional
Pssm-ID: 185037 [Multi-domain] Cd Length: 331 Bit Score: 107.10 E-value: 1.34e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 12 PNGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLAERDVPYFRRQLGVIFQD--FK 89
Cdd:PRK15079 31 PKTLKAVDGVTLRLYEGETLGVVGESGCGKSTFARAIIGLVKATDGEVAWLGKDLLGMKDDEWRAVRSDIQMIFQDplAS 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 90 LLPKLTVYENVSFALEVIEEE--PDAIRERVTEVLGLVGL-EDRADALPSELSGGEQQRVAIARAIVNRPKVVIADEPTG 166
Cdd:PRK15079 111 LNPRMTIGEIIAEPLRTYHPKlsRQEVKDRVKAMMLKVGLlPNLINRYPHEFSGGQCQRIGIARALILEPKLIICDEPVS 190
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 446516975 167 NLDIETALDIMNIFTRIN-ERGTTIVMATHNADIVNTIRHRVI 208
Cdd:PRK15079 191 ALDVSIQAQVVNLLQQLQrEMGLSLIFIAHDLAVVKHISDRVL 233
|
|
| AztA |
NF040873 |
zinc ABC transporter ATP-binding protein AztA; |
13-208 |
4.24e-27 |
|
zinc ABC transporter ATP-binding protein AztA;
Pssm-ID: 468810 [Multi-domain] Cd Length: 191 Bit Score: 102.31 E-value: 4.24e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 13 NGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGltietlaERDVPYFRRQLGVIfqdfKLLP 92
Cdd:NF040873 3 GGRPVLHGVDLTIPAGSLTAVVGPNGSGKSTLLKVLAGVLRPTSGTVRRAG-------GARVAYVPQRSEVP----DSLP 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 93 kLTVYENVS---FALEVIEEEPDAI-RERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIVNRPKVVIADEPTGNL 168
Cdd:NF040873 72 -LTVRDLVAmgrWARRGLWRRLTRDdRAAVDDALERVGLADLAGRQLGELSGGQRQRALLAQGLAQEADLLLLDEPTTGL 150
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 446516975 169 DIETALDIMNIFTRINERGTTIVMATHNADIVNTIRHRVI 208
Cdd:NF040873 151 DAESRERIIALLAEEHARGATVVVVTHDLELVRRADPCVL 190
|
|
| ATM1 |
COG5265 |
ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components ... |
20-216 |
4.81e-27 |
|
ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444078 [Multi-domain] Cd Length: 605 Bit Score: 108.37 E-value: 4.81e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 20 GLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIetlaeRDVP--YFRRQLGVIFQDfKLLPKLTVY 97
Cdd:COG5265 376 GVSFEVPAGKTVAIVGPSGAGKSTLARLLFRFYDVTSGRILIDGQDI-----RDVTqaSLRAAIGIVPQD-TVLFNDTIA 449
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 98 ENVSFAlevieeEPDAIRERVTEVLGLVGLEDRADALPS-----------ELSGGEQQRVAIARAIVNRPKVVIADEPTG 166
Cdd:COG5265 450 YNIAYG------RPDASEEEVEAAARAAQIHDFIESLPDgydtrvgerglKLSGGEKQRVAIARTLLKNPPILIFDEATS 523
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 446516975 167 NLDIETALDIMNIFTRINERGTTIVMAtHNadiVNTIRH--RVIAIEGGKIV 216
Cdd:COG5265 524 ALDSRTERAIQAALREVARGRTTLVIA-HR---LSTIVDadEILVLEAGRIV 571
|
|
| cbiO |
PRK13648 |
cobalt transporter ATP-binding subunit; Provisional |
24-198 |
6.75e-27 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184207 [Multi-domain] Cd Length: 269 Bit Score: 104.06 E-value: 6.75e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 24 NIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLAERDVpyfRRQLGVIFQDfkllPK-----LTVYE 98
Cdd:PRK13648 31 NIPKGQWTSIVGHNGSGKSTIAKLMIGIEKVKSGEIFYNNQAITDDNFEKL---RKHIGIVFQN----PDnqfvgSIVKY 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 99 NVSFALEVIEEEPDAIRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIVNRPKVVIADEPTGNLDIETALDIMN 178
Cdd:PRK13648 104 DVAFGLENHAVPYDEMHRRVSEALKQVDMLERADYEPNALSGGQKQRVAIAGVLALNPSVIILDEATSMLDPDARQNLLD 183
|
170 180
....*....|....*....|.
gi 446516975 179 IFTRIN-ERGTTIVMATHNAD 198
Cdd:PRK13648 184 LVRKVKsEHNITIISITHDLS 204
|
|
| PRK10261 |
PRK10261 |
glutathione transporter ATP-binding protein; Provisional |
17-216 |
7.33e-27 |
|
glutathione transporter ATP-binding protein; Provisional
Pssm-ID: 182342 [Multi-domain] Cd Length: 623 Bit Score: 107.63 E-value: 7.33e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 17 AIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLAERDVPYFRRQLGVIFQD--FKLLPKL 94
Cdd:PRK10261 339 AVEKVSFDLWPGETLSLVGESGSGKSTTGRALLRLVESQGGEIIFNGQRIDTLSPGKLQALRRDIQFIFQDpyASLDPRQ 418
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 95 TVYENVSFALEVIE-EEPDAIRERVTEVLGLVGLE-DRADALPSELSGGEQQRVAIARAIVNRPKVVIADEPTGNLDIET 172
Cdd:PRK10261 419 TVGDSIMEPLRVHGlLPGKAAAARVAWLLERVGLLpEHAWRYPHEFSGGQRQRICIARALALNPKVIIADEAVSALDVSI 498
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 446516975 173 ALDIMNIFTRIN-ERGTTIVMATHNADIVNTIRHRVIAIEGGKIV 216
Cdd:PRK10261 499 RGQIINLLLDLQrDFGIAYLFISHDMAVVERISHRVAVMYLGQIV 543
|
|
| type_I_sec_PrtD |
TIGR01842 |
type I secretion system ABC transporter, PrtD family; Type I protein secretion is a system in ... |
6-220 |
9.51e-27 |
|
type I secretion system ABC transporter, PrtD family; Type I protein secretion is a system in some Gram-negative bacteria to export proteins (often proteases) across both inner and outer membranes to the extracellular medium. This is one of three proteins of the type I secretion apparatus. Targeted proteins are not cleaved at the N-terminus, but rather carry signals located toward the extreme C-terminus to direct type I secretion. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 200134 [Multi-domain] Cd Length: 544 Bit Score: 107.05 E-value: 9.51e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 6 NVYKEYPNGMKAI-AGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIEtlaERDVPYFRRQLGVI 84
Cdd:TIGR01842 321 NVTIVPPGGKKPTlRGISFSLQAGEALAIIGPSGSGKSTLARLIVGIWPPTSGSVRLDGADLK---QWDRETFGKHIGYL 397
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 85 FQDFKLLPKlTVYENVSfaleVIEEEPDAirERVTEVLGLVGLEDRADALP-----------SELSGGEQQRVAIARAIV 153
Cdd:TIGR01842 398 PQDVELFPG-TVAENIA----RFGENADP--EKIIEAAKLAGVHELILRLPdgydtvigpggATLSGGQRQRIALARALY 470
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446516975 154 NRPKVVIADEPTGNLDIETALDIMNIFTRINERGTTIVMATHNADIVNTIrHRVIAIEGGKIV----RDEI 220
Cdd:TIGR01842 471 GDPKLVVLDEPNSNLDEEGEQALANAIKALKARGITVVVITHRPSLLGCV-DKILVLQDGRIArfgeRDEV 540
|
|
| PRK15134 |
PRK15134 |
microcin C ABC transporter ATP-binding protein YejF; Provisional |
17-216 |
1.68e-26 |
|
microcin C ABC transporter ATP-binding protein YejF; Provisional
Pssm-ID: 237917 [Multi-domain] Cd Length: 529 Bit Score: 106.33 E-value: 1.68e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 17 AIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREeKPSTGSINVNGLTIETLAERDVPYFRRQLGVIFQD--FKLLPKL 94
Cdd:PRK15134 301 VVKNISFTLRPGETLGLVGESGSGKSTTGLALLRL-INSQGEIWFDGQPLHNLNRRQLLPVRHRIQVVFQDpnSSLNPRL 379
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 95 TVYENVSFALEVIEEEPDAIR--ERVTEVLGLVGLE-DRADALPSELSGGEQQRVAIARAIVNRPKVVIADEPTGNLDIE 171
Cdd:PRK15134 380 NVLQIIEEGLRVHQPTLSAAQreQQVIAVMEEVGLDpETRHRYPAEFSGGQRQRIAIARALILKPSLIILDEPTSSLDKT 459
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 446516975 172 TALDIMNIFTRINER-GTTIVMATHNADIVNTIRHRVIAIEGGKIV 216
Cdd:PRK15134 460 VQAQILALLKSLQQKhQLAYLFISHDLHVVRALCHQVIVLRQGEVV 505
|
|
| PRK13536 |
PRK13536 |
nodulation factor ABC transporter ATP-binding protein NodI; |
2-214 |
1.85e-26 |
|
nodulation factor ABC transporter ATP-binding protein NodI;
Pssm-ID: 237419 [Multi-domain] Cd Length: 340 Bit Score: 104.14 E-value: 1.85e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 2 IKMTNVYKEYpnGMKAIA-GLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLAERDvpyfRRQ 80
Cdd:PRK13536 42 IDLAGVSKSY--GDKAVVnGLSFTVASGECFGLLGPNGAGKSTIARMILGMTSPDAGKITVLGVPVPARARLA----RAR 115
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 81 LGVIFQDFKLLPKLTVYENVSFALEVIEEEPDAIRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIVNRPKVVI 160
Cdd:PRK13536 116 IGVVPQFDNLDLEFTVRENLLVFGRYFGMSTREIEAVIPSLLEFARLESKADARVSDLSGGMKRRLTLARALINDPQLLI 195
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 446516975 161 ADEPTGNLDIETALDIMNIFTRINERGTTIVMATHNADIVNTIRHRVIAIEGGK 214
Cdd:PRK13536 196 LDEPTTGLDPHARHLIWERLRSLLARGKTILLTTHFMEEAERLCDRLCVLEAGR 249
|
|
| YddA |
COG4178 |
ABC-type uncharacterized transport system, permease and ATPase components [General function ... |
12-213 |
1.86e-26 |
|
ABC-type uncharacterized transport system, permease and ATPase components [General function prediction only];
Pssm-ID: 443337 [Multi-domain] Cd Length: 571 Bit Score: 106.43 E-value: 1.86e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 12 PNGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMyreekpstgsinvNGL------TIETLAERDV------PYF-- 77
Cdd:COG4178 373 PDGRPLLEDLSLSLKPGERLLITGPSGSGKSTLLRAI-------------AGLwpygsgRIARPAGARVlflpqrPYLpl 439
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 78 ---RRQLgvifqdfkLLPKltvyenvsfalevieeEPDAI-RERVTEVLGLVGLEDRADAL------PSELSGGEQQRVA 147
Cdd:COG4178 440 gtlREAL--------LYPA----------------TAEAFsDAELREALEAVGLGHLAERLdeeadwDQVLSLGEQQRLA 495
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446516975 148 IARAIVNRPKVVIADEPTGNLDIETALDIMnifTRINER--GTTIVMATHNADIVNtiRH-RVIAIEGG 213
Cdd:COG4178 496 FARLLLHKPDWLFLDEATSALDEENEAALY---QLLREElpGTTVISVGHRSTLAA--FHdRVLELTGD 559
|
|
| Uup |
COG0488 |
ATPase components of ABC transporters with duplicated ATPase domains [General function ... |
1-224 |
2.75e-26 |
|
ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];
Pssm-ID: 440254 [Multi-domain] Cd Length: 520 Bit Score: 105.53 E-value: 2.75e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 1 MIKMTNVYKEYPnGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVnGLTIEtlaerdVPYFRrq 80
Cdd:COG0488 315 VLELEGLSKSYG-DKTLLDDLSLRIDRGDRIGLIGPNGAGKSTLLKLLAGELEPDSGTVKL-GETVK------IGYFD-- 384
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 81 lgvifQDFKLL-PKLTVYENVSfaleviEEEPDAIRERVTEVLGLVGL-EDRADALPSELSGGEQQRVAIARAIVNRPKV 158
Cdd:COG0488 385 -----QHQEELdPDKTVLDELR------DGAPGGTEQEVRGYLGRFLFsGDDAFKPVGVLSGGEKARLALAKLLLSPPNV 453
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446516975 159 VIADEPTGNLDIETaLDIMNIFtrINERGTTIVMATHNADIVNTIRHRVIAIEGGKIVrdEIEGGY 224
Cdd:COG0488 454 LLLDEPTNHLDIET-LEALEEA--LDDFPGTVLLVSHDRYFLDRVATRILEFEDGGVR--EYPGGY 514
|
|
| met_CoM_red_A2 |
TIGR03269 |
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ... |
2-216 |
5.98e-26 |
|
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]
Pssm-ID: 132313 [Multi-domain] Cd Length: 520 Bit Score: 104.88 E-value: 5.98e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 2 IKMTNVYKEYpNGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMM--YREEKPSTGSINVNGLTIE------------ 67
Cdd:TIGR03269 1 IEVKNLTKKF-DGKEVLKNISFTIEEGEVLGILGRSGAGKSVLMHVLrgMDQYEPTSGRIIYHVALCEkcgyverpskvg 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 68 --------TLAERDVPY----------FRRQLGVIFQ-DFKLLPKLTVYENVSFALEVIEEEPDAIRERVTEVLGLVGLE 128
Cdd:TIGR03269 80 epcpvcggTLEPEEVDFwnlsdklrrrIRKRIAIMLQrTFALYGDDTVLDNVLEALEEIGYEGKEAVGRAVDLIEMVQLS 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 129 DRADALPSELSGGEQQRVAIARAIVNRPKVVIADEPTGNLDIETALDIMN-IFTRINERGTTIVMATHNADIVNTIRHRV 207
Cdd:TIGR03269 160 HRITHIARDLSGGEKQRVVLARQLAKEPFLFLADEPTGTLDPQTAKLVHNaLEEAVKASGISMVLTSHWPEVIEDLSDKA 239
|
....*....
gi 446516975 208 IAIEGGKIV 216
Cdd:TIGR03269 240 IWLENGEIK 248
|
|
| LptB |
COG1137 |
ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope ... |
1-196 |
5.99e-26 |
|
ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440752 [Multi-domain] Cd Length: 240 Bit Score: 100.87 E-value: 5.99e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 1 MIKMTNVYKEYpNGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLaerdvPYFRR- 79
Cdd:COG1137 3 TLEAENLVKSY-GKRTVVKDVSLEVNQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGRIFLDGEDITHL-----PMHKRa 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 80 QLGV--------IFQdfkllpKLTVYENVSFALEVIEEEPDAIRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARA 151
Cdd:COG1137 77 RLGIgylpqeasIFR------KLTVEDNILAVLELRKLSKKEREERLEELLEEFGITHLRKSKAYSLSGGERRRVEIARA 150
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 446516975 152 IVNRPKVVIADEPTGNLDIETALDIMNIFTRINERGTTIVMATHN 196
Cdd:COG1137 151 LATNPKFILLDEPFAGVDPIAVADIQKIIRHLKERGIGVLITDHN 195
|
|
| PRK14258 |
PRK14258 |
phosphate ABC transporter ATP-binding protein; Provisional |
2-196 |
6.78e-26 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 184593 [Multi-domain] Cd Length: 261 Bit Score: 101.27 E-value: 6.78e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 2 IKMTNVYKEYpNGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPStGSINVNG---LTIETLAERDVPY-- 76
Cdd:PRK14258 8 IKVNNLSFYY-DTQKILEGVSMEIYQSKVTAIIGPSGCGKSTFLKCLNRMNELE-SEVRVEGrveFFNQNIYERRVNLnr 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 77 FRRQLGVIFQDFKLLPkLTVYENVSFALEVIEEEP----DAIRE---RVTEVLGLVGLEDRADALpsELSGGEQQRVAIA 149
Cdd:PRK14258 86 LRRQVSMVHPKPNLFP-MSVYDNVAYGVKIVGWRPkleiDDIVEsalKDADLWDEIKHKIHKSAL--DLSGGQQQRLCIA 162
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 446516975 150 RAIVNRPKVVIADEPTGNLDIETALDIMNIFTRINERGT-TIVMATHN 196
Cdd:PRK14258 163 RALAVKPKVLLMDEPCFGLDPIASMKVESLIQSLRLRSElTMVIVSHN 210
|
|
| ABC_Carb_Monos_I |
cd03216 |
First domain of the ATP-binding cassette component of monosaccharide transport system; This ... |
2-216 |
9.44e-26 |
|
First domain of the ATP-binding cassette component of monosaccharide transport system; This family represents the domain I of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. Pentoses include xylose, arabinose, and ribose. Important hexoses include glucose, galactose, and fructose. In members of the Carb_monos family, the single hydrophobic gene product forms a homodimer while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.
Pssm-ID: 213183 [Multi-domain] Cd Length: 163 Bit Score: 98.27 E-value: 9.44e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 2 IKMTNVYKEYPnGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLAERDvpyfRRQL 81
Cdd:cd03216 1 LELRGITKRFG-GVKALDGVSLSVRRGEVHALLGENGAGKSTLMKILSGLYKPDSGEILVDGKEVSFASPRD----ARRA 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 82 GV--IFQdfkllpkltvyenvsfalevieeepdairervtevlglvgledradalpseLSGGEQQRVAIARAIVNRPKVV 159
Cdd:cd03216 76 GIamVYQ---------------------------------------------------LSVGERQMVEIARALARNARLL 104
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 446516975 160 IADEPTGNLDIETALDIMNIFTRINERGTTIVMATHNADIVNTIRHRVIAIEGGKIV 216
Cdd:cd03216 105 ILDEPTAALTPAEVERLFKVIRRLRAQGVAVIFISHRLDEVFEIADRVTVLRDGRVV 161
|
|
| dppD |
PRK11022 |
dipeptide transporter ATP-binding subunit; Provisional |
16-216 |
1.29e-25 |
|
dipeptide transporter ATP-binding subunit; Provisional
Pssm-ID: 182906 [Multi-domain] Cd Length: 326 Bit Score: 101.74 E-value: 1.29e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 16 KAIAGLTVNIKQGEFVYVVGPSGAGKS-TFIKMMYREEKP---STGSINVNGLTIETLAERDvpyfRRQL-----GVIFQ 86
Cdd:PRK11022 21 RAVDRISYSVKQGEVVGIVGESGSGKSvSSLAIMGLIDYPgrvMAEKLEFNGQDLQRISEKE----RRNLvgaevAMIFQ 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 87 D--FKLLPKLTVYENVSFALEVIEEEPDAIR-ERVTEVLGLVGLED---RADALPSELSGGEQQRVAIARAIVNRPKVVI 160
Cdd:PRK11022 97 DpmTSLNPCYTVGFQIMEAIKVHQGGNKKTRrQRAIDLLNQVGIPDpasRLDVYPHQLSGGMSQRVMIAMAIACRPKLLI 176
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 446516975 161 ADEPTGNLDIETALDIMNIFTRINER-GTTIVMATHNADIVNTIRHRVIAIEGGKIV 216
Cdd:PRK11022 177 ADEPTTALDVTIQAQIIELLLELQQKeNMALVLITHDLALVAEAAHKIIVMYAGQVV 233
|
|
| PRK11174 |
PRK11174 |
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed |
12-195 |
1.68e-25 |
|
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
Pssm-ID: 236870 [Multi-domain] Cd Length: 588 Bit Score: 103.77 E-value: 1.68e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 12 PNGmKAIAG-LTVNIKQGEFVYVVGPSGAGKSTFIKMM-----YReekpstGSINVNGltIEtLAERDVPYFRRQLGVIF 85
Cdd:PRK11174 360 PDG-KTLAGpLNFTLPAGQRIALVGPSGAGKTSLLNALlgflpYQ------GSLKING--IE-LRELDPESWRKHLSWVG 429
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 86 QDfKLLPKLTVYENVSFAlevieeEPDAIRERVTEVLGLVGLEDRADALP-----------SELSGGEQQRVAIARAIVN 154
Cdd:PRK11174 430 QN-PQLPHGTLRDNVLLG------NPDASDEQLQQALENAWVSEFLPLLPqgldtpigdqaAGLSVGQAQRLALARALLQ 502
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 446516975 155 RPKVVIADEPTGNLDIETALDIMNIFTRINERGTTIvMATH 195
Cdd:PRK11174 503 PCQLLLLDEPTASLDAHSEQLVMQALNAASRRQTTL-MVTH 542
|
|
| ABCC_TAP |
cd03248 |
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; ... |
2-215 |
1.91e-25 |
|
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; TAP (Transporter Associated with Antigen Processing) is essential for peptide delivery from the cytosol into the lumen of the endoplasmic reticulum (ER), where these peptides are loaded on major histocompatibility complex (MHC) I molecules. Loaded MHC I leave the ER and display their antigenic cargo on the cell surface to cytotoxic T cells. Subsequently, virus-infected or malignantly transformed cells can be eliminated. TAP belongs to the large family of ATP-binding cassette (ABC) transporters, which translocate a vast variety of solutes across membranes.
Pssm-ID: 213215 [Multi-domain] Cd Length: 226 Bit Score: 99.08 E-value: 1.91e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 2 IKMTNVYKEYPN--GMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLAERdvpYFRR 79
Cdd:cd03248 12 VKFQNVTFAYPTrpDTLVLQDVSFTLHPGEVTALVGPSGSGKSTVVALLENFYQPQGGQVLLDGKPISQYEHK---YLHS 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 80 QLGVIFQDFKLLPKlTVYENVSFALevieeePDAIRERVTEVLGLVGLEDRADALP-----------SELSGGEQQRVAI 148
Cdd:cd03248 89 KVSLVGQEPVLFAR-SLQDNIAYGL------QSCSFECVKEAAQKAHAHSFISELAsgydtevgekgSQLSGGQKQRVAI 161
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446516975 149 ARAIVNRPKVVIADEPTGNLDIETALDIMNIFTRINERGTTIVMATHnadiVNTIR--HRVIAIEGGKI 215
Cdd:cd03248 162 ARALIRNPQVLILDEATSALDAESEQQVQQALYDWPERRTVLVIAHR----LSTVEraDQILVLDGGRI 226
|
|
| ABCC_MRP_domain2 |
cd03244 |
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C ... |
2-216 |
2.24e-25 |
|
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resistance lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213211 [Multi-domain] Cd Length: 221 Bit Score: 98.72 E-value: 2.24e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 2 IKMTNVYKEY-PNGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLAERDVpyfRRQ 80
Cdd:cd03244 3 IEFKNVSLRYrPNLPPVLKNISFSIKPGEKVGIVGRTGSGKSSLLLALFRLVELSSGSILIDGVDISKIGLHDL---RSR 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 81 LGVIFQDfkllPKL---TVYENvsfaLEVIEEEPDairERVTEVLGLVGLEDRADALP-----------SELSGGEQQRV 146
Cdd:cd03244 80 ISIIPQD----PVLfsgTIRSN----LDPFGEYSD---EELWQALERVGLKEFVESLPggldtvveeggENLSVGQRQLL 148
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446516975 147 AIARAIVNRPKVVIADEPTGNLDIETALDIMNIfTRINERGTTIVMATHNadiVNTIRH--RVIAIEGGKIV 216
Cdd:cd03244 149 CLARALLRKSKILVLDEATASVDPETDALIQKT-IREAFKDCTVLTIAHR---LDTIIDsdRILVLDKGRVV 216
|
|
| ArpD |
COG4618 |
ABC-type protease/lipase transport system, ATPase and permease components [Intracellular ... |
11-220 |
4.64e-25 |
|
ABC-type protease/lipase transport system, ATPase and permease components [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 443660 [Multi-domain] Cd Length: 563 Bit Score: 102.52 E-value: 4.64e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 11 YPNGMKAI-AGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLAERDvpyFRRQLGVIFQDFK 89
Cdd:COG4618 340 PPGSKRPIlRGVSFSLEPGEVLGVIGPSGSGKSTLARLLVGVWPPTAGSVRLDGADLSQWDREE---LGRHIGYLPQDVE 416
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 90 LLPKlTVYENVS-FalevieeePDAIRERVTEVLGLVGLEDRADALP-----------SELSGGEQQRVAIARAIVNRPK 157
Cdd:COG4618 417 LFDG-TIAENIArF--------GDADPEKVVAAAKLAGVHEMILRLPdgydtrigeggARLSGGQRQRIGLARALYGDPR 487
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446516975 158 VVIADEPTGNLD--IETALdiMNIFTRINERGTTIVMATHNADIVNTIrHRVIAIEGGKIV----RDEI 220
Cdd:COG4618 488 LVVLDEPNSNLDdeGEAAL--AAAIRALKARGATVVVITHRPSLLAAV-DKLLVLRDGRVQafgpRDEV 553
|
|
| Uup |
COG0488 |
ATPase components of ABC transporters with duplicated ATPase domains [General function ... |
4-224 |
4.82e-25 |
|
ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];
Pssm-ID: 440254 [Multi-domain] Cd Length: 520 Bit Score: 102.07 E-value: 4.82e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 4 MTNVYKEYPNgmKAI-AGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINV-NGLTIETLAerdvpyfrrql 81
Cdd:COG0488 1 LENLSKSFGG--RPLlDDVSLSINPGDRIGLVGRNGAGKSTLLKILAGELEPDSGEVSIpKGLRIGYLP----------- 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 82 gvifQDFKLLPKLTVYENV--SF-----------ALEVIEEEPDAIRERVTEVLG-----------------LVGL---E 128
Cdd:COG0488 68 ----QEPPLDDDLTVLDTVldGDaelraleaeleELEAKLAEPDEDLERLAELQEefealggweaearaeeiLSGLgfpE 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 129 DRADALPSELSGGEQQRVAIARAIVNRPKVVIADEPTGNLDIETAL---DIMNiftriNERGtTIVMATHNADIVNTIRH 205
Cdd:COG0488 144 EDLDRPVSELSGGWRRRVALARALLSEPDLLLLDEPTNHLDLESIEwleEFLK-----NYPG-TVLVVSHDRYFLDRVAT 217
|
250
....*....|....*....
gi 446516975 206 RVIAIEGGKIvrDEIEGGY 224
Cdd:COG0488 218 RILELDRGKL--TLYPGNY 234
|
|
| urea_trans_UrtE |
TIGR03410 |
urea ABC transporter, ATP-binding protein UrtE; Members of this protein family are ABC ... |
17-216 |
5.90e-25 |
|
urea ABC transporter, ATP-binding protein UrtE; Members of this protein family are ABC transporter ATP-binding subunits associated with urea transport and metabolism. This protein is found in a conserved five-gene transport operon typically found adjacent to urease genes. It was shown in Cyanobacteria that disruption leads to the loss of high-affinity urea transport activity. [Transport and binding proteins, Amino acids, peptides and amines]
Pssm-ID: 274567 [Multi-domain] Cd Length: 230 Bit Score: 97.98 E-value: 5.90e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 17 AIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLAerdvPYFRRQLGVIF--QDFKLLPKL 94
Cdd:TIGR03410 15 ILRGVSLEVPKGEVTCVLGRNGVGKTTLLKTLMGLLPVKSGSIRLDGEDITKLP----PHERARAGIAYvpQGREIFPRL 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 95 TVYENVSFALEVIeeePDAIRERVTEVLGLVG-LEDRADALPSELSGGEQQRVAIARAIVNRPKVVIADEPTGNLDIETA 173
Cdd:TIGR03410 91 TVEENLLTGLAAL---PRRSRKIPDEIYELFPvLKEMLGRRGGDLSGGQQQQLAIARALVTRPKLLLLDEPTEGIQPSII 167
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 446516975 174 LDIMNIFTRIN-ERGTTIVMATHNADIVNTIRHRVIAIEGGKIV 216
Cdd:TIGR03410 168 KDIGRVIRRLRaEGGMAILLVEQYLDFARELADRYYVMERGRVV 211
|
|
| PRK10575 |
PRK10575 |
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC; |
21-216 |
1.28e-24 |
|
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;
Pssm-ID: 182561 [Multi-domain] Cd Length: 265 Bit Score: 97.94 E-value: 1.28e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 21 LTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGltiETLAERDVPYFRRQLGVIFQDFKLLPKLTVYENV 100
Cdd:PRK10575 30 LSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDA---QPLESWSSKAFARKVAYLPQQLPAAEGMTVRELV 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 101 SF-------ALEVIEEEPdaiRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIVNRPKVVIADEPTGNLDIETA 173
Cdd:PRK10575 107 AIgrypwhgALGRFGAAD---REKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLLLDEPTSALDIAHQ 183
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 446516975 174 LDIMNIFTRIN-ERGTTIVMATHNADIVNTIRHRVIAIEGGKIV 216
Cdd:PRK10575 184 VDVLALVHRLSqERGLTVIAVLHDINMAARYCDYLVALRGGEMI 227
|
|
| PRK10253 |
PRK10253 |
iron-enterobactin ABC transporter ATP-binding protein; |
14-216 |
3.94e-24 |
|
iron-enterobactin ABC transporter ATP-binding protein;
Pssm-ID: 182336 [Multi-domain] Cd Length: 265 Bit Score: 96.59 E-value: 3.94e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 14 GMKAIA-GLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLAERDVPyfrRQLGVIFQDFKLLP 92
Cdd:PRK10253 18 GKYTVAeNLTVEIPDGHFTAIIGPNGCGKSTLLRTLSRLMTPAHGHVWLDGEHIQHYASKEVA---RRIGLLAQNATTPG 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 93 KLTVYENVS---------FALEVIEEEpdairERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIVNRPKVVIADE 163
Cdd:PRK10253 95 DITVQELVArgryphqplFTRWRKEDE-----EAVTKAMQATGITHLADQSVDTLSGGQRQRAWIAMVLAQETAIMLLDE 169
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 446516975 164 PTGNLDIETALDIMNIFTRIN-ERGTTIVMATHNADIVNTIRHRVIAIEGGKIV 216
Cdd:PRK10253 170 PTTWLDISHQIDLLELLSELNrEKGYTLAAVLHDLNQACRYASHLIALREGKIV 223
|
|
| ccmA |
TIGR01189 |
heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein ... |
13-197 |
6.25e-24 |
|
heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein encoded by ccmA in bacteria. An exception is, an arabidopsis protein. Quite likely this is encoded by an organelle. Bacterial c-type cytocromes are located on the periplasmic side of the cytoplasmic membrane. Several gene products encoded in a locus designated as 'ccm' are implicated in the transport and assembly of the functional cytochrome C. This cluster includes genes: ccmA;B;C;D;E;F;G and H. The posttranslational pathway includes the transport of heme moiety, the secretion of the apoprotein and the covalent attachment of the heme with the apoprotein. The proteins ccmA and B represent an ABC transporter; ccmC and D participate in heme transfer to ccmE, which function as a periplasmic heme chaperone. The presence of ccmF, G and H is suggested to be obligatory for the final functional assembly of cytochrome c. [Protein fate, Protein and peptide secretion and trafficking, Transport and binding proteins, Other]
Pssm-ID: 273491 [Multi-domain] Cd Length: 198 Bit Score: 94.35 E-value: 6.25e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 13 NGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLaeRDVPYfrRQLGVIFQDFKLLP 92
Cdd:TIGR01189 11 GERMLFEGLSFTLNAGEALQVTGPNGIGKTTLLRILAGLLRPDSGEVRWNGTPLAEQ--RDEPH--ENILYLGHLPGLKP 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 93 KLTVYENVSFALEVIEEEpdaiRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIVNRPKVVIADEPTGNLDIET 172
Cdd:TIGR01189 87 ELSALENLHFWAAIHGGA----QRTIEDALAAVGLTGFEDLPAAQLSAGQQRRLALARLWLSRRPLWILDEPTTALDKAG 162
|
170 180
....*....|....*....|....*
gi 446516975 173 ALDIMNIFTRINERGTTIVMATHNA 197
Cdd:TIGR01189 163 VALLAGLLRAHLARGGIVLLTTHQD 187
|
|
| PRK11831 |
PRK11831 |
phospholipid ABC transporter ATP-binding protein MlaF; |
21-216 |
6.69e-24 |
|
phospholipid ABC transporter ATP-binding protein MlaF;
Pssm-ID: 236997 [Multi-domain] Cd Length: 269 Bit Score: 95.99 E-value: 6.69e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 21 LTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLAERDVPYFRRQLGVIFQDFKLLPKLTVYENV 100
Cdd:PRK11831 26 ISLTVPRGKITAIMGPSGIGKTTLLRLIGGQIAPDHGEILFDGENIPAMSRSRLYTVRKRMSMLFQSGALFTDMNVFDNV 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 101 SFALEVIEEEPDAI-RERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIVNRPKVVIADEPTGNLDIETALDIMNI 179
Cdd:PRK11831 106 AYPLREHTQLPAPLlHSTVMMKLEAVGLRGAAKLMPSELSGGMARRAALARAIALEPDLIMFDEPFVGQDPITMGVLVKL 185
|
170 180 190
....*....|....*....|....*....|....*...
gi 446516975 180 FTRINER-GTTIVMATHNADIVNTIRHRVIAIEGGKIV 216
Cdd:PRK11831 186 ISELNSAlGVTCVVVSHDVPEVLSIADHAYIVADKKIV 223
|
|
| PRK14239 |
PRK14239 |
phosphate transporter ATP-binding protein; Provisional |
11-196 |
9.42e-24 |
|
phosphate transporter ATP-binding protein; Provisional
Pssm-ID: 184585 [Multi-domain] Cd Length: 252 Bit Score: 95.23 E-value: 9.42e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 11 YPNGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYR-----EEKPSTGSINVNGLTIETlAERDVPYFRRQLGVIF 85
Cdd:PRK14239 14 YYNKKKALNSVSLDFYPNEITALIGPSGSGKSTLLRSINRmndlnPEVTITGSIVYNGHNIYS-PRTDTVDLRKEIGMVF 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 86 QDFKLLPkLTVYENVSFALEVIEEEPDAIRERVTEVlGLVG------LEDRADALPSELSGGEQQRVAIARAIVNRPKVV 159
Cdd:PRK14239 93 QQPNPFP-MSIYENVVYGLRLKGIKDKQVLDEAVEK-SLKGasiwdeVKDRLHDSALGLSGGQQQRVCIARVLATSPKII 170
|
170 180 190
....*....|....*....|....*....|....*..
gi 446516975 160 IADEPTGNLDIETALDIMNIFTRINERgTTIVMATHN 196
Cdd:PRK14239 171 LLDEPTSALDPISAGKIEETLLGLKDD-YTMLLVTRS 206
|
|
| oppD |
PRK09473 |
oligopeptide transporter ATP-binding component; Provisional |
12-214 |
1.21e-23 |
|
oligopeptide transporter ATP-binding component; Provisional
Pssm-ID: 181888 [Multi-domain] Cd Length: 330 Bit Score: 96.33 E-value: 1.21e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 12 PNG-MKAIAGLTVNIKQGEFVYVVGPSGAGKS--TFIKM-MYREEKPSTGSINVNGLTIETLAERDVPYFR-RQLGVIFQ 86
Cdd:PRK09473 25 PDGdVTAVNDLNFSLRAGETLGIVGESGSGKSqtAFALMgLLAANGRIGGSATFNGREILNLPEKELNKLRaEQISMIFQ 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 87 D--FKLLPKLTVYENVsfaLEVIE-----EEPDAIRERVtEVLGLVGLED---RADALPSELSGGEQQRVAIARAIVNRP 156
Cdd:PRK09473 105 DpmTSLNPYMRVGEQL---MEVLMlhkgmSKAEAFEESV-RMLDAVKMPEarkRMKMYPHEFSGGMRQRVMIAMALLCRP 180
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 446516975 157 KVVIADEPTGNLDIETALDIMNIFTRI-NERGTTIVMATHNADIVNTIRHRVIAIEGGK 214
Cdd:PRK09473 181 KLLIADEPTTALDVTVQAQIMTLLNELkREFNTAIIMITHDLGVVAGICDKVLVMYAGR 239
|
|
| MK0520 |
COG2401 |
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction ... |
15-216 |
1.25e-23 |
|
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction only];
Pssm-ID: 441957 [Multi-domain] Cd Length: 222 Bit Score: 94.25 E-value: 1.25e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 15 MKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEK--PSTGSINVNGLTIEtlaerdvpyfrrqlgvifqdfkllP 92
Cdd:COG2401 43 RYVLRDLNLEIEPGEIVLIVGASGSGKSTLLRLLAGALKgtPVAGCVDVPDNQFG------------------------R 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 93 KLTVYENVSfalevIEEEPDAirerVTEVLGLVGLEDRAD--ALPSELSGGEQQRVAIARAIVNRPKVVIADEPTGNLDI 170
Cdd:COG2401 99 EASLIDAIG-----RKGDFKD----AVELLNAVGLSDAVLwlRRFKELSTGQKFRFRLALLLAERPKLLVIDEFCSHLDR 169
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 446516975 171 ETALDIMNIFTRI-NERGTTIVMATHNADIVNTIRHRVIAIEGGKIV 216
Cdd:COG2401 170 QTAKRVARNLQKLaRRAGITLVVATHHYDVIDDLQPDLLIFVGYGGV 216
|
|
| ABCC_cytochrome_bd |
cd03247 |
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome ... |
2-216 |
1.35e-23 |
|
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome bd biogenesis. The CydC and CydD proteins are important for the formation of cytochrome bd terminal oxidase of E. coli and it has been proposed that they were necessary for biosynthesis of the cytochrome bd quinol oxidase and for periplasmic c-type cytochromes. CydCD were proposed to determine a heterooligomeric complex important for heme export into the periplasm or to be involved in the maintenance of the proper redox state of the periplasmic space. In Bacillus subtilis, the absence of CydCD does not affect the presence of halo-cytochrome c in the membrane and this observation suggests that CydCD proteins are not involved in the export of heme in this organism.
Pssm-ID: 213214 [Multi-domain] Cd Length: 178 Bit Score: 93.15 E-value: 1.35e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 2 IKMTNVYKEYP-NGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLAERdvpyFRRQ 80
Cdd:cd03247 1 LSINNVSFSYPeQEQQVLKNLSLELKQGEKIALLGRSGSGKSTLLQLLTGDLKPQQGEITLDGVPVSDLEKA----LSSL 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 81 LGVIFQDFKLLPKlTVYENvsfalevieeepdairervtevLGLvgledradalpsELSGGEQQRVAIARAIVNRPKVVI 160
Cdd:cd03247 77 ISVLNQRPYLFDT-TLRNN----------------------LGR------------RFSGGERQRLALARILLQDAPIVL 121
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 446516975 161 ADEPTGNLDIETALDIMNIFTRInERGTTIVMATHNadiVNTIRH--RVIAIEGGKIV 216
Cdd:cd03247 122 LDEPTVGLDPITERQLLSLIFEV-LKDKTLIWITHH---LTGIEHmdKILFLENGKII 175
|
|
| 3a01204 |
TIGR00955 |
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, ... |
25-195 |
1.65e-23 |
|
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273361 [Multi-domain] Cd Length: 617 Bit Score: 98.20 E-value: 1.65e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 25 IKQGEFVYVVGPSGAGKSTFIK-MMYREEKPST--GSINVNGLTIetlaerDVPYFRRQLGVIFQDFKLLPKLTVYENVS 101
Cdd:TIGR00955 48 AKPGELLAVMGSSGAGKTTLMNaLAFRSPKGVKgsGSVLLNGMPI------DAKEMRAISAYVQQDDLFIPTLTVREHLM 121
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 102 FALEVIEEEP---DAIRERVTEVLGLVGLEDRADAL---PSE---LSGGEQQRVAIARAIVNRPKVVIADEPTGNLDIET 172
Cdd:TIGR00955 122 FQAHLRMPRRvtkKEKRERVDEVLQALGLRKCANTRigvPGRvkgLSGGERKRLAFASELLTDPPLLFCDEPTSGLDSFM 201
|
170 180
....*....|....*....|...
gi 446516975 173 ALDIMNIFTRINERGTTIVMATH 195
Cdd:TIGR00955 202 AYSVVQVLKGLAQKGKTIICTIH 224
|
|
| btuD |
PRK09536 |
corrinoid ABC transporter ATPase; Reviewed |
1-199 |
1.68e-23 |
|
corrinoid ABC transporter ATPase; Reviewed
Pssm-ID: 236554 [Multi-domain] Cd Length: 402 Bit Score: 97.22 E-value: 1.68e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 1 MIKMTNVYKEYpNGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLAERDVPyfrRQ 80
Cdd:PRK09536 3 MIDVSDLSVEF-GDTTVLDGVDLSVREGSLVGLVGPNGAGKTTLLRAINGTLTPTAGTVLVAGDDVEALSARAAS---RR 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 81 LGVIFQDFKLLPKLTVYENVSFA-------LEVIEEEPDAIRERVTEVLGLVGLEDRAdalPSELSGGEQQRVAIARAIV 153
Cdd:PRK09536 79 VASVPQDTSLSFEFDVRQVVEMGrtphrsrFDTWTETDRAAVERAMERTGVAQFADRP---VTSLSGGERQRVLLARALA 155
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 446516975 154 NRPKVVIADEPTGNLDIETALDIMNIFTRINERGTTIVMATHNADI 199
Cdd:PRK09536 156 QATPVLLLDEPTASLDINHQVRTLELVRRLVDDGKTAVAAIHDLDL 201
|
|
| cbiO |
PRK13646 |
energy-coupling factor transporter ATPase; |
2-216 |
3.96e-23 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184205 [Multi-domain] Cd Length: 286 Bit Score: 94.46 E-value: 3.96e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 2 IKMTNVYKEYPNGM----KAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTI-ETLAERDVPY 76
Cdd:PRK13646 3 IRFDNVSYTYQKGTpyehQAIHDVNTEFEQGKYYAIVGQTGSGKSTLIQNINALLKPTTGTVTVDDITItHKTKDKYIRP 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 77 FRRQLGVIFQdfklLPKLTVYEN-----VSFALEVIEEEPDAIRERVTEVLGLVGLE-DRADALPSELSGGEQQRVAIAR 150
Cdd:PRK13646 83 VRKRIGMVFQ----FPESQLFEDtvereIIFGPKNFKMNLDEVKNYAHRLLMDLGFSrDVMSQSPFQMSGGQMRKIAIVS 158
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446516975 151 AIVNRPKVVIADEPTGNLDIETALDIMNIFTRIN-ERGTTIVMATHNADIVNTIRHRVIAIEGGKIV 216
Cdd:PRK13646 159 ILAMNPDIIVLDEPTAGLDPQSKRQVMRLLKSLQtDENKTIILVSHDMNEVARYADEVIVMKEGSIV 225
|
|
| CP_lyasePhnK |
TIGR02323 |
phosphonate C-P lyase system protein PhnK; Members of this family are the PhnK protein of C-P ... |
1-216 |
4.02e-23 |
|
phosphonate C-P lyase system protein PhnK; Members of this family are the PhnK protein of C-P lyase systems for utilization of phosphonates. These systems resemble phosphonatase-based systems in having a three component ABC transporter, where TIGR01097 is the permease, TIGR01098 is the phosphonates binding protein, and TIGR02315 is the ATP-binding cassette (ABC) protein. They differ, however, in having, typically, ten or more additional genes, many of which are believed to form a membrane-associated complex. This protein (PhnK) and the adjacent-encoded PhnL resemble transporter ATP-binding proteins but are suggested, based on mutatgenesis studies, to be part of this complex rather than part of a transporter per se. [Central intermediary metabolism, Phosphorus compounds]
Pssm-ID: 188208 [Multi-domain] Cd Length: 253 Bit Score: 93.74 E-value: 4.02e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 1 MIKMTNVYKEYPNGmKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSI---NVNGLTIE--TLAERDvp 75
Cdd:TIGR02323 3 LLQVSGLSKSYGGG-KGCRDVSFDLYPGEVLGIVGESGSGKSTLLGCLAGRLAPDHGTAtyiMRSGAELElyQLSEAE-- 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 76 yfRRQL-----GVIFQDfkllPKLTVYENVSfALEVIEEEPDA--------IRERVTEVLGLVGLE-DRADALPSELSGG 141
Cdd:TIGR02323 80 --RRRLmrtewGFVHQN----PRDGLRMRVS-AGANIGERLMAigarhygnIRATAQDWLEEVEIDpTRIDDLPRAFSGG 152
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446516975 142 EQQRVAIARAIVNRPKVVIADEPTGNLDIETALDIMNIFTR-INERGTTIVMATHNADIVNTIRHRVIAIEGGKIV 216
Cdd:TIGR02323 153 MQQRLQIARNLVTRPRLVFMDEPTGGLDVSVQARLLDLLRGlVRDLGLAVIIVTHDLGVARLLAQRLLVMQQGRVV 228
|
|
| cbiO |
PRK13640 |
energy-coupling factor transporter ATPase; |
11-216 |
4.36e-23 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184200 [Multi-domain] Cd Length: 282 Bit Score: 94.10 E-value: 4.36e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 11 YPNGMK-AIAGLTVNIKQGEFVYVVGPSGAGKSTFIKM----MYREEKPSTgSINVNGLTietLAERDVPYFRRQLGVIF 85
Cdd:PRK13640 15 YPDSKKpALNDISFSIPRGSWTALIGHNGSGKSTISKLinglLLPDDNPNS-KITVDGIT---LTAKTVWDIREKVGIVF 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 86 Q--DFKLLPKlTVYENVSFALE---VIEEEPDAIrerVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIVNRPKVVI 160
Cdd:PRK13640 91 QnpDNQFVGA-TVGDDVAFGLEnraVPRPEMIKI---VRDVLADVGMLDYIDSEPANLSGGQKQRVAIAGILAVEPKIII 166
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 446516975 161 ADEPTGNLDIETALDIMNIFTRI-NERGTTIVMATHNADIVNtIRHRVIAIEGGKIV 216
Cdd:PRK13640 167 LDESTSMLDPAGKEQILKLIRKLkKKNNLTVISITHDIDEAN-MADQVLVLDDGKLL 222
|
|
| PRK14267 |
PRK14267 |
phosphate ABC transporter ATP-binding protein; Provisional |
18-216 |
5.87e-23 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 184596 [Multi-domain] Cd Length: 253 Bit Score: 93.37 E-value: 5.87e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 18 IAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYR-----EEKPSTGSINVNGLTIETlAERDVPYFRRQLGVIFQDFKLLP 92
Cdd:PRK14267 20 IKGVDLKIPQNGVFALMGPSGCGKSTLLRTFNRllelnEEARVEGEVRLFGRNIYS-PDVDPIEVRREVGMVFQYPNPFP 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 93 KLTVYENVSFALEV--IEEEPDAIRERVTEVLGLVGL----EDRADALPSELSGGEQQRVAIARAIVNRPKVVIADEPTG 166
Cdd:PRK14267 99 HLTIYDNVAIGVKLngLVKSKKELDERVEWALKKAALwdevKDRLNDYPSNLSGGQRQRLVIARALAMKPKILLMDEPTA 178
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 446516975 167 NLDIETALDIMNIFTRINERgTTIVMATHNADIVNTIRHRVIAIEGGKIV 216
Cdd:PRK14267 179 NIDPVGTAKIEELLFELKKE-YTIVLVTHSPAQAARVSDYVAFLYLGKLI 227
|
|
| ABC_KpsT_Wzt |
cd03220 |
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC ... |
2-219 |
6.92e-23 |
|
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC transporter subfamily is involved in extracellular polysaccharide export. Among the variety of membrane-linked or extracellular polysaccharides excreted by bacteria, only capsular polysaccharides, lipopolysaccharides, and teichoic acids have been shown to be exported by ABC transporters. A typical system is made of a conserved integral membrane and an ABC. In addition to these proteins, capsular polysaccharide exporter systems require two 'accessory' proteins to perform their function: a periplasmic (E.coli) or a lipid-anchored outer membrane protein called OMA (Neisseria meningitidis and Haemophilus influenza) and a cytoplasmic membrane protein MPA2.
Pssm-ID: 213187 [Multi-domain] Cd Length: 224 Bit Score: 92.21 E-value: 6.92e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 2 IKMTNVYKEYPNGMK---------------------AIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSIN 60
Cdd:cd03220 1 IELENVSKSYPTYKGgssslkklgilgrkgevgefwALKDVSFEVPRGERIGLIGRNGAGKSTLLRLLAGIYPPDSGTVT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 61 VNGltietlaeRDVPYFRrqLGVIFQdfkllPKLTVYENVSFALEVIEEEPDAIRERVTEVLGLVGLEDRADALPSELSG 140
Cdd:cd03220 81 VRG--------RVSSLLG--LGGGFN-----PELTGRENIYLNGRLLGLSRKEIDEKIDEIIEFSELGDFIDLPVKTYSS 145
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446516975 141 GEQQRVAIARAIVNRPKVVIADEPTGNLDIETALDIMNIFTRINERGTTIVMATHNADIVNTIRHRVIAIEGGKIVRDE 219
Cdd:cd03220 146 GMKARLAFAIATALEPDILLIDEVLAVGDAAFQEKCQRRLRELLKQGKTVILVSHDPSSIKRLCDRALVLEKGKIRFDG 224
|
|
| PRK10895 |
PRK10895 |
lipopolysaccharide ABC transporter ATP-binding protein; Provisional |
6-216 |
1.05e-22 |
|
lipopolysaccharide ABC transporter ATP-binding protein; Provisional
Pssm-ID: 182817 [Multi-domain] Cd Length: 241 Bit Score: 92.26 E-value: 1.05e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 6 NVYKEYpNGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVN--GLTIETLAERDvpyfRRQLGV 83
Cdd:PRK10895 8 NLAKAY-KGRRVVEDVSLTVNSGEIVGLLGPNGAGKTTTFYMVVGIVPRDAGNIIIDdeDISLLPLHARA----RRGIGY 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 84 IFQDFKLLPKLTVYENVSFALEVIEEEPDAIRE-RVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIVNRPKVVIAD 162
Cdd:PRK10895 83 LPQEASIFRRLSVYDNLMAVLQIRDDLSAEQREdRANELMEEFHIEHLRDSMGQSLSGGERRRVEIARALAANPKFILLD 162
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 446516975 163 EPTGNLDIETALDIMNIFTRINERGTTIVMATHNADIVNTIRHRVIAIEGGKIV 216
Cdd:PRK10895 163 EPFAGVDPISVIDIKRIIEHLRDSGLGVLITDHNVRETLAVCERAYIVSQGHLI 216
|
|
| 3a01208 |
TIGR00958 |
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other] |
2-216 |
1.27e-22 |
|
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273363 [Multi-domain] Cd Length: 711 Bit Score: 95.56 E-value: 1.27e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 2 IKMTNVYKEYPN--GMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGltiETLAERDVPYFRR 79
Cdd:TIGR00958 479 IEFQDVSFSYPNrpDVPVLKGLTFTLHPGEVVALVGPSGSGKSTVAALLQNLYQPTGGQVLLDG---VPLVQYDHHYLHR 555
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 80 QLGVIFQDfKLLPKLTVYENVSFALEVIEEEpdaireRVTEVLGLVGLEDRADALP-----------SELSGGEQQRVAI 148
Cdd:TIGR00958 556 QVALVGQE-PVLFSGSVRENIAYGLTDTPDE------EIMAAAKAANAHDFIMEFPngydtevgekgSQLSGGQKQRIAI 628
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446516975 149 ARAIVNRPKVVIADEPTGNLDIEtaldIMNIFTRINERGT-TIVMATHNadiVNTIR--HRVIAIEGGKIV 216
Cdd:TIGR00958 629 ARALVRKPRVLILDEATSALDAE----CEQLLQESRSRASrTVLLIAHR---LSTVEraDQILVLKKGSVV 692
|
|
| PRK15112 |
PRK15112 |
peptide ABC transporter ATP-binding protein SapF; |
15-216 |
1.54e-22 |
|
peptide ABC transporter ATP-binding protein SapF;
Pssm-ID: 185067 [Multi-domain] Cd Length: 267 Bit Score: 92.55 E-value: 1.54e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 15 MKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGltiETLAERDVPYFRRQLGVIFQD--FKLLP 92
Cdd:PRK15112 26 VEAVKPLSFTLREGQTLAIIGENGSGKSTLAKMLAGMIEPTSGELLIDD---HPLHFGDYSYRSQRIRMIFQDpsTSLNP 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 93 KLTVYENVSFALEV-IEEEPDAIRERVTEVLGLVGL-EDRADALPSELSGGEQQRVAIARAIVNRPKVVIADEPTGNLDI 170
Cdd:PRK15112 103 RQRISQILDFPLRLnTDLEPEQREKQIIETLRQVGLlPDHASYYPHMLAPGQKQRLGLARALILRPKVIIADEALASLDM 182
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 446516975 171 ETALDIMNIFTRINER-GTTIVMATHNADIVNTIRHRVIAIEGGKIV 216
Cdd:PRK15112 183 SMRSQLINLMLELQEKqGISYIYVTQHLGMMKHISDQVLVMHQGEVV 229
|
|
| BtuD |
COG4138 |
ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism]; ... |
19-216 |
2.94e-22 |
|
ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism];
Pssm-ID: 443313 [Multi-domain] Cd Length: 248 Bit Score: 91.06 E-value: 2.94e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 19 AGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEkPSTGSINVNGltiETLAERDVPYFRRQLGVIFQDFKLLPKLTVYE 98
Cdd:COG4138 13 GPISAQVNAGELIHLIGPNGAGKSTLLARMAGLL-PGQGEILLNG---RPLSDWSAAELARHRAYLSQQQSPPFAMPVFQ 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 99 NVSFALEVIEEEPdAIRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAI------VN-RPKVVIADEPTGNLDI- 170
Cdd:COG4138 89 YLALHQPAGASSE-AVEQLLAQLAEALGLEDKLSRPLTQLSGGEWQRVRLAAVLlqvwptINpEGQLLLLDEPMNSLDVa 167
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 446516975 171 -ETALDimNIFTRINERGTTIVMATHnaDIVNTIRH--RVIAIEGGKIV 216
Cdd:COG4138 168 qQAALD--RLLRELCQQGITVVMSSH--DLNHTLRHadRVWLLKQGKLV 212
|
|
| livF |
PRK11614 |
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF; |
1-216 |
4.09e-22 |
|
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;
Pssm-ID: 183231 [Multi-domain] Cd Length: 237 Bit Score: 90.71 E-value: 4.09e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 1 MIKMTNVYKEYpNGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLAERDVpyFRRQ 80
Cdd:PRK11614 5 MLSFDKVSAHY-GKIQALHEVSLHINQGEIVTLIGANGAGKTTLLGTLCGDPRATSGRIVFDGKDITDWQTAKI--MREA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 81 LGVIFQDFKLLPKLTVYENVsfALEVIEEEPDAIRERVTEVLGLVG-LEDRADALPSELSGGEQQRVAIARAIVNRPKVV 159
Cdd:PRK11614 82 VAIVPEGRRVFSRMTVEENL--AMGGFFAERDQFQERIKWVYELFPrLHERRIQRAGTMSGGEQQMLAIGRALMSQPRLL 159
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 446516975 160 IADEPTGNLDIETALDIMNIFTRINERGTTIVMATHNADIVNTIRHRVIAIEGGKIV 216
Cdd:PRK11614 160 LLDEPSLGLAPIIIQQIFDTIEQLREQGMTIFLVEQNANQALKLADRGYVLENGHVV 216
|
|
| ABC_Carb_Monos_II |
cd03215 |
Second domain of the ATP-binding cassette component of monosaccharide transport system; This ... |
16-215 |
4.80e-22 |
|
Second domain of the ATP-binding cassette component of monosaccharide transport system; This family represents domain II of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. In members of Carb_Monos family the single hydrophobic gene product forms a homodimer, while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.
Pssm-ID: 213182 [Multi-domain] Cd Length: 182 Bit Score: 89.03 E-value: 4.80e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 16 KAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIEtlaeRDVPYFRRQLGVIF-----QDFKL 90
Cdd:cd03215 14 GAVRDVSFEVRAGEIVGIAGLVGNGQTELAEALFGLRPPASGEITLDGKPVT----RRSPRDAIRAGIAYvpedrKREGL 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 91 LPKLTVYENVsfalevieeepdairervtevlglvgledradALPSELSGGEQQRVAIARAIVNRPKVVIADEPTGNLDI 170
Cdd:cd03215 90 VLDLSVAENI--------------------------------ALSSLLSGGNQQKVVLARWLARDPRVLILDEPTRGVDV 137
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 446516975 171 ETALDIMNIFTRINERGTTIVMAT-------HNADivntirhRVIAIEGGKI 215
Cdd:cd03215 138 GAKAEIYRLIRELADAGKAVLLISseldellGLCD-------RILVMYEGRI 182
|
|
| phnK |
PRK11701 |
phosphonate C-P lyase system protein PhnK; Provisional |
28-216 |
5.10e-22 |
|
phosphonate C-P lyase system protein PhnK; Provisional
Pssm-ID: 183280 [Multi-domain] Cd Length: 258 Bit Score: 90.76 E-value: 5.10e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 28 GEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNG-----LTIETLAERDvpyfRRQL-----GVIFQDFK--LLPKLT 95
Cdd:PRK11701 32 GEVLGIVGESGSGKTTLLNALSARLAPDAGEVHYRMrdgqlRDLYALSEAE----RRRLlrtewGFVHQHPRdgLRMQVS 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 96 VYENVSFALEVI-EEEPDAIRERVTEVLGLVGLE-DRADALPSELSGGEQQRVAIARAIVNRPKVVIADEPTGNLDIETA 173
Cdd:PRK11701 108 AGGNIGERLMAVgARHYGDIRATAGDWLERVEIDaARIDDLPTTFSGGMQQRLQIARNLVTHPRLVFMDEPTGGLDVSVQ 187
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 446516975 174 ---LDIMNIFTRinERGTTIVMATHNADIVNTIRHRVIAIEGGKIV 216
Cdd:PRK11701 188 arlLDLLRGLVR--ELGLAVVIVTHDLAVARLLAHRLLVMKQGRVV 231
|
|
| PRK13538 |
PRK13538 |
cytochrome c biogenesis heme-transporting ATPase CcmA; |
20-195 |
7.47e-22 |
|
cytochrome c biogenesis heme-transporting ATPase CcmA;
Pssm-ID: 184125 [Multi-domain] Cd Length: 204 Bit Score: 89.09 E-value: 7.47e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 20 GLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLAE---RDVPYFRRQLGVifqdfKllPKLTV 96
Cdd:PRK13538 19 GLSFTLNAGELVQIEGPNGAGKTSLLRILAGLARPDAGEVLWQGEPIRRQRDeyhQDLLYLGHQPGI-----K--TELTA 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 97 YENVSFALEvIEEEPDaiRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIVNRPKVVIADEPTGNLDIETALDI 176
Cdd:PRK13538 92 LENLRFYQR-LHGPGD--DEALWEALAQVGLAGFEDVPVRQLSAGQQRRVALARLWLTRAPLWILDEPFTAIDKQGVARL 168
|
170
....*....|....*....
gi 446516975 177 MNIFTRINERGTTIVMATH 195
Cdd:PRK13538 169 EALLAQHAEQGGMVILTTH 187
|
|
| cbiO |
PRK13631 |
cobalt transporter ATP-binding subunit; Provisional |
4-217 |
1.15e-21 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237451 [Multi-domain] Cd Length: 320 Bit Score: 91.07 E-value: 1.15e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 4 MTNVYKE-YPNGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTI--ETLAERDVPY---- 76
Cdd:PRK13631 27 LYCVFDEkQENELVALNNISYTFEKNKIYFIIGNSGSGKSTLVTHFNGLIKSKYGTIQVGDIYIgdKKNNHELITNpysk 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 77 -------FRRQLGVIFQ--DFKLLpKLTVYENVSF---ALEVIEEEPdaiRERVTEVLGLVGL-EDRADALPSELSGGEQ 143
Cdd:PRK13631 107 kiknfkeLRRRVSMVFQfpEYQLF-KDTIEKDIMFgpvALGVKKSEA---KKLAKFYLNKMGLdDSYLERSPFGLSGGQK 182
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446516975 144 QRVAIARAIVNRPKVVIADEPTGNLDIETALDIMNIFTRINERGTTIVMATHNADIVNTIRHRVIAIEGGKIVR 217
Cdd:PRK13631 183 RRVAIAGILAIQPEILIFDEPTAGLDPKGEHEMMQLILDAKANNKTVFVITHTMEHVLEVADEVIVMDKGKILK 256
|
|
| cbiO |
PRK13642 |
energy-coupling factor transporter ATPase; |
10-218 |
2.02e-21 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184202 [Multi-domain] Cd Length: 277 Bit Score: 89.77 E-value: 2.02e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 10 EYPNGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGltiETLAERDVPYFRRQLGVIFQD-F 88
Cdd:PRK13642 15 EKESDVNQLNGVSFSITKGEWVSIIGQNGSGKSTTARLIDGLFEEFEGKVKIDG---ELLTAENVWNLRRKIGMVFQNpD 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 89 KLLPKLTVYENVSFALEVIEEEPDAIRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIVNRPKVVIADEPTGNL 168
Cdd:PRK13642 92 NQFVGATVEDDVAFGMENQGIPREEMIKRVDEALLAVNMLDFKTREPARLSGGQKQRVAVAGIIALRPEIIILDESTSML 171
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 446516975 169 DIETALDIMNIFTRINER-GTTIVMATHNADIVNTiRHRVIAIEGGKIVRD 218
Cdd:PRK13642 172 DPTGRQEIMRVIHEIKEKyQLTVLSITHDLDEAAS-SDRILVMKAGEIIKE 221
|
|
| bacteriocin_ABC |
TIGR01193 |
ABC-type bacteriocin transporter; This model describes ABC-type bacteriocin transporter. The ... |
2-218 |
3.04e-21 |
|
ABC-type bacteriocin transporter; This model describes ABC-type bacteriocin transporter. The amino terminal domain (pfam03412) processes the N-terminal leader peptide from the bacteriocin while C-terminal domains resemble ABC transporter membrane protein and ATP-binding cassette domain. In general, bacteriocins are agents which are responsible for killing or inhibiting the closely related species or even different strains of the same species. Bacteriocins are usually encoded by bacterial plasmids. Bacteriocins are named after the species and hence in literature one encounters various names e.g., leucocin from Leuconostic geldium; pedicocin from Pedicoccus acidilactici; sakacin from Lactobacillus sake etc. [Protein fate, Protein and peptide secretion and trafficking, Protein fate, Protein modification and repair, Transport and binding proteins, Other]
Pssm-ID: 130261 [Multi-domain] Cd Length: 708 Bit Score: 91.72 E-value: 3.04e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 2 IKMTNVYKEYPNGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLaerDVPYFRRQL 81
Cdd:TIGR01193 474 IVINDVSYSYGYGSNILSDISLTIKMNSKTTIVGMSGSGKSTLAKLLVGFFQARSGEILLNGFSLKDI---DRHTLRQFI 550
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 82 GVIFQDFKLLPKlTVYENVsfaleVIEEEPDAIRERVTEVLGLVGLEDRADALP-----------SELSGGEQQRVAIAR 150
Cdd:TIGR01193 551 NYLPQEPYIFSG-SILENL-----LLGAKENVSQDEIWAACEIAEIKDDIENMPlgyqtelseegSSISGGQKQRIALAR 624
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446516975 151 AIVNRPKVVIADEPTGNLDIETALDIMNIFTRINERgtTIVMATHNADIVNTIrHRVIAIEGGKIVRD 218
Cdd:TIGR01193 625 ALLTDSKVLILDESTSNLDTITEKKIVNNLLNLQDK--TIIFVAHRLSVAKQS-DKIIVLDHGKIIEQ 689
|
|
| PRK09700 |
PRK09700 |
D-allose ABC transporter ATP-binding protein AlsA; |
1-216 |
6.87e-21 |
|
D-allose ABC transporter ATP-binding protein AlsA;
Pssm-ID: 182036 [Multi-domain] Cd Length: 510 Bit Score: 90.23 E-value: 6.87e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 1 MIKMTNVYKEYPnGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLAERDVpyFRRQ 80
Cdd:PRK09700 5 YISMAGIGKSFG-PVHALKSVNLTVYPGEIHALLGENGAGKSTLMKVLSGIHEPTKGTITINNINYNKLDHKLA--AQLG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 81 LGVIFQDFKLLPKLTVYENV---------SFALEVIEEEpdAIRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARA 151
Cdd:PRK09700 82 IGIIYQELSVIDELTVLENLyigrhltkkVCGVNIIDWR--EMRVRAAMMLLRVGLKVDLDEKVANLSISHKQMLEIAKT 159
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446516975 152 IVNRPKVVIADEPTGNL---DIETALDIMNiftRINERGTTIVMATHNADIVNTIRHRVIAIEGGKIV 216
Cdd:PRK09700 160 LMLDAKVIIMDEPTSSLtnkEVDYLFLIMN---QLRKEGTAIVYISHKLAEIRRICDRYTVMKDGSSV 224
|
|
| rim_protein |
TIGR01257 |
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ... |
12-215 |
8.19e-21 |
|
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]
Pssm-ID: 130324 [Multi-domain] Cd Length: 2272 Bit Score: 90.46 E-value: 8.19e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 12 PNGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETlaerDVPYFRRQLGVIFQDFKLL 91
Cdd:TIGR01257 940 PSGRPAVDRLNITFYENQITAFLGHNGAGKTTTLSILTGLLPPTSGTVLVGGKDIET----NLDAVRQSLGMCPQHNILF 1015
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 92 PKLTVYENVSFALEVIEEEPDAIRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIVNRPKVVIADEPTGNLDIE 171
Cdd:TIGR01257 1016 HHLTVAEHILFYAQLKGRSWEEAQLEMEAMLEDTGLHHKRNEEAQDLSGGMQRKLSVAIAFVGDAKVVVLDEPTSGVDPY 1095
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 446516975 172 TALDIMNIFTRINErGTTIVMATHNADIVNTIRHRVIAIEGGKI 215
Cdd:TIGR01257 1096 SRRSIWDLLLKYRS-GRTIIMSTHHMDEADLLGDRIAIISQGRL 1138
|
|
| fecE |
PRK11231 |
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE; |
1-216 |
1.12e-20 |
|
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;
Pssm-ID: 183044 [Multi-domain] Cd Length: 255 Bit Score: 86.99 E-value: 1.12e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 1 MIKMTNVYKEYPNgMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLAERDvpyFRRQ 80
Cdd:PRK11231 2 TLRTENLTVGYGT-KRILNDLSLSLPTGKITALIGPNGCGKSTLLKCFARLLTPQSGTVFLGDKPISMLSSRQ---LARR 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 81 LGVIFQDFkLLPK-LTVYENVSFA----LEVIEEEPDAIRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIVNR 155
Cdd:PRK11231 78 LALLPQHH-LTPEgITVRELVAYGrspwLSLWGRLSAEDNARVNQAMEQTRINHLADRRLTDLSGGQRQRAFLAMVLAQD 156
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446516975 156 PKVVIADEPTGNLDIETALDIMNIFTRINERGTTIVMATHnaDIVNTIRH--RVIAIEGGKIV 216
Cdd:PRK11231 157 TPVVLLDEPTTYLDINHQVELMRLMRELNTQGKTVVTVLH--DLNQASRYcdHLVVLANGHVM 217
|
|
| ABCD_peroxisomal_ALDP |
cd03223 |
ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding ... |
12-195 |
1.16e-20 |
|
ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding cassette transporter (Pat) is involved in the import of very long-chain fatty acids (VLCFA) into the peroxisome. The peroxisomal membrane forms a permeability barrier for a wide variety of metabolites required for and formed during fatty acid beta-oxidation. To communicate with the cytoplasm and mitochondria, peroxisomes need dedicated proteins to transport such hydrophilic molecules across their membranes. X-linked adrenoleukodystrophy (X-ALD) is caused by mutations in the ALD gene, which encodes ALDP (adrenoleukodystrophy protein ), a peroxisomal integral membrane protein that is a member of the ATP-binding cassette (ABC) transporter protein family. The disease is characterized by a striking and unpredictable variation in phenotypic expression. Phenotypes include the rapidly progressive childhood cerebral form (CCALD), the milder adult form, adrenomyeloneuropathy (AMN), and variants without neurologic involvement (i.e. asymptomatic).
Pssm-ID: 213190 [Multi-domain] Cd Length: 166 Bit Score: 84.90 E-value: 1.16e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 12 PNGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMyreekpstgsinvNGL------TIETLAERDV------PYFrr 79
Cdd:cd03223 11 PDGRVLLKDLSFEIKPGDRLLITGPSGTGKSSLFRAL-------------AGLwpwgsgRIGMPEGEDLlflpqrPYL-- 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 80 qlgvifqdfkllPKLTVYENVSFALEvieeepdairervtevlglvgledradalpSELSGGEQQRVAIARAIVNRPKVV 159
Cdd:cd03223 76 ------------PLGTLREQLIYPWD------------------------------DVLSGGEQQRLAFARLLLHKPKFV 113
|
170 180 190
....*....|....*....|....*....|....*.
gi 446516975 160 IADEPTGNLDIETALDIMNIftrINERGTTIVMATH 195
Cdd:cd03223 114 FLDEATSALDEESEDRLYQL---LKELGITVISVGH 146
|
|
| PRK15439 |
PRK15439 |
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional |
1-216 |
1.54e-20 |
|
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
Pssm-ID: 185336 [Multi-domain] Cd Length: 510 Bit Score: 89.34 E-value: 1.54e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 1 MIKMTNVYKEYpNGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLAerdvPYFRRQ 80
Cdd:PRK15439 11 LLCARSISKQY-SGVEVLKGIDFTLHAGEVHALLGGNGAGKSTLMKIIAGIVPPDSGTLEIGGNPCARLT----PAKAHQ 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 81 LGV--IFQDFKLLPKLTVYENVSFALEvieeEPDAIRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIVNRPKV 158
Cdd:PRK15439 86 LGIylVPQEPLLFPNLSVKENILFGLP----KRQASMQKMKQLLAALGCQLDLDSSAGSLEVADRQIVEILRGLMRDSRI 161
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446516975 159 VIADEPTGNLdieTALDIMNIFTRINE---RGTTIVMATHNADIVNTIRHRVIAIEGGKIV 216
Cdd:PRK15439 162 LILDEPTASL---TPAETERLFSRIREllaQGVGIVFISHKLPEIRQLADRISVMRDGTIA 219
|
|
| ABC_CcmA_heme_exporter |
cd03231 |
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the ... |
20-195 |
1.67e-20 |
|
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the bacterial CcmAB transporter. The CCM family is involved in bacterial cytochrome c biogenesis. Cytochrome c maturation in E. coli requires the ccm operon, which encodes eight membrane proteins (CcmABCDEFGH). CcmE is a periplasmic heme chaperon that binds heme covalently and transfers it onto apocytochrome c in the presence of CcmF, CcmG, and CcmH. The CcmAB proteins represent an ABC transporter and the CcmCD proteins participate in heme transfer to CcmE.
Pssm-ID: 213198 [Multi-domain] Cd Length: 201 Bit Score: 85.62 E-value: 1.67e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 20 GLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGltieTLAERDVPYFRRQLGVIFQDFKLLPKLTVYEN 99
Cdd:cd03231 18 GLSFTLAAGEALQVTGPNGSGKTTLLRILAGLSPPLAGRVLLNG----GPLDFQRDSIARGLLYLGHAPGIKTTLSVLEN 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 100 VSFAlevieeEPDAIRERVTEVL---GLVGLEDRADAlpsELSGGEQQRVAIARAIVNRPKVVIADEPTGNLDIETALDI 176
Cdd:cd03231 94 LRFW------HADHSDEQVEEALarvGLNGFEDRPVA---QLSAGQQRRVALARLLLSGRPLWILDEPTTALDKAGVARF 164
|
170
....*....|....*....
gi 446516975 177 MNIFTRINERGTTIVMATH 195
Cdd:cd03231 165 AEAMAGHCARGGMVVLTTH 183
|
|
| PRK03695 |
PRK03695 |
vitamin B12-transporter ATPase; Provisional |
21-220 |
2.13e-20 |
|
vitamin B12-transporter ATPase; Provisional
Pssm-ID: 235150 [Multi-domain] Cd Length: 248 Bit Score: 86.14 E-value: 2.13e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 21 LTVNIKQGEFVYVVGPSGAGKSTFIKMMyREEKPSTGSINVNGLTIETLAERDVPYFRRQLGvifQDFKLLPKLTVYENV 100
Cdd:PRK03695 15 LSAEVRAGEILHLVGPNGAGKSTLLARM-AGLLPGSGSIQFAGQPLEAWSAAELARHRAYLS---QQQTPPFAMPVFQYL 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 101 SFALEViEEEPDAIRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAI-----VNRP--KVVIADEPTGNLDI--E 171
Cdd:PRK03695 91 TLHQPD-KTRTEAVASALNEVAEALGLDDKLGRSVNQLSGGEWQRVRLAAVVlqvwpDINPagQLLLLDEPMNSLDVaqQ 169
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 446516975 172 TALDimNIFTRINERGTTIVMATHnaDIVNTIRH--RVIAIEGGKIV----RDEI 220
Cdd:PRK03695 170 AALD--RLLSELCQQGIAVVMSSH--DLNHTLRHadRVWLLKQGKLLasgrRDEV 220
|
|
| PRK10247 |
PRK10247 |
putative ABC transporter ATP-binding protein YbbL; Provisional |
13-201 |
2.44e-20 |
|
putative ABC transporter ATP-binding protein YbbL; Provisional
Pssm-ID: 182331 [Multi-domain] Cd Length: 225 Bit Score: 85.54 E-value: 2.44e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 13 NGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLA-ERdvpyFRRQLGVIFQDfkll 91
Cdd:PRK10247 18 GDAKILNNISFSLRAGEFKLITGPSGCGKSTLLKIVASLISPTSGTLLFEGEDISTLKpEI----YRQQVSYCAQT---- 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 92 PKL---TVYENVSFALEVIEEEPDaiRERVTEVLGLVGL-EDRADALPSELSGGEQQRVAIARAIVNRPKVVIADEPTGN 167
Cdd:PRK10247 90 PTLfgdTVYDNLIFPWQIRNQQPD--PAIFLDDLERFALpDTILTKNIAELSGGEKQRISLIRNLQFMPKVLLLDEITSA 167
|
170 180 190
....*....|....*....|....*....|....*
gi 446516975 168 LDIETALDIMNIFTRIN-ERGTTIVMATHNADIVN 201
Cdd:PRK10247 168 LDESNKHNVNEIIHRYVrEQNIAVLWVTHDKDEIN 202
|
|
| ABCC_MRP_domain1 |
cd03250 |
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This ... |
20-214 |
3.10e-20 |
|
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This subfamily is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213217 [Multi-domain] Cd Length: 204 Bit Score: 84.83 E-value: 3.10e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 20 GLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGltieTLAErdVPyfrrQLGVIFQDfkllpklTVYEN 99
Cdd:cd03250 23 DINLEVPKGELVAIVGPVGSGKSSLLSALLGELEKLSGSVSVPG----SIAY--VS----QEPWIQNG-------TIREN 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 100 VSFALEVIEEepdaireRVTEVLGLVGLEDRADALP-----------SELSGGEQQRVAIARAIVNRPKVVIADEPTGNL 168
Cdd:cd03250 86 ILFGKPFDEE-------RYEKVIKACALEPDLEILPdgdlteigekgINLSGGQKQRISLARAVYSDADIYLLDDPLSAV 158
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 446516975 169 DIETALDIM-NIFTRINERGTTIVMATHNadiVNTIRH--RVIAIEGGK 214
Cdd:cd03250 159 DAHVGRHIFeNCILGLLLNNKTRILVTHQ---LQLLPHadQIVVLDNGR 204
|
|
| PRK13539 |
PRK13539 |
cytochrome c biogenesis protein CcmA; Provisional |
19-196 |
3.12e-20 |
|
cytochrome c biogenesis protein CcmA; Provisional
Pssm-ID: 237421 [Multi-domain] Cd Length: 207 Bit Score: 84.93 E-value: 3.12e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 19 AGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGltietlAERDVPYFRRQ---LGviFQDFkLLPKLT 95
Cdd:PRK13539 19 SGLSFTLAAGEALVLTGPNGSGKTTLLRLIAGLLPPAAGTIKLDG------GDIDDPDVAEAchyLG--HRNA-MKPALT 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 96 VYENVSFALEVIEEEPDAIrERVTEVLGLVGLEDRADAlpsELSGGEQQRVAIAR-AIVNRPkVVIADEPTGNLDIETAL 174
Cdd:PRK13539 90 VAENLEFWAAFLGGEELDI-AAALEAVGLAPLAHLPFG---YLSAGQKRRVALARlLVSNRP-IWILDEPTAALDAAAVA 164
|
170 180
....*....|....*....|..
gi 446516975 175 DIMNIFTRINERGTTIVMATHN 196
Cdd:PRK13539 165 LFAELIRAHLAQGGIVIAATHI 186
|
|
| SapD |
COG4170 |
ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms]; |
12-196 |
3.44e-20 |
|
ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms];
Pssm-ID: 443330 [Multi-domain] Cd Length: 331 Bit Score: 86.88 E-value: 3.44e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 12 PNG-MKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPST---------GSINVNGLTIEtlAERDVpyFRRQL 81
Cdd:COG4170 16 PQGrVKAVDRVSLTLNEGEIRGLVGESGSGKSLIAKAICGITKDNWhvtadrfrwNGIDLLKLSPR--ERRKI--IGREI 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 82 GVIFQDFK--LLPKLTVYENVSFALEVIE------EEPDAIRERVTEVLGLVGLEDRAD---ALPSELSGGEQQRVAIAR 150
Cdd:COG4170 92 AMIFQEPSscLDPSAKIGDQLIEAIPSWTfkgkwwQRFKWRKKRAIELLHRVGIKDHKDimnSYPHELTEGECQKVMIAM 171
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 446516975 151 AIVNRPKVVIADEPTGNLDIETALDIMNIFTRINE-RGTTIVMATHN 196
Cdd:COG4170 172 AIANQPRLLIADEPTNAMESTTQAQIFRLLARLNQlQGTSILLISHD 218
|
|
| TagH |
COG1134 |
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate ... |
1-219 |
5.69e-20 |
|
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440749 [Multi-domain] Cd Length: 245 Bit Score: 85.13 E-value: 5.69e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 1 MIKMTNVYKEYPNGMK---------------------AIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSI 59
Cdd:COG1134 4 MIEVENVSKSYRLYHEpsrslkelllrrrrtrreefwALKDVSFEVERGESVGIIGRNGAGKSTLLKLIAGILEPTSGRV 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 60 NVNGlTIETLAErdvpyfrrqLGVIFQdfkllPKLTVYENVSFALEVIEEEPDAIRERVTEVLGLVGLEDRADaLP-SEL 138
Cdd:COG1134 84 EVNG-RVSALLE---------LGAGFH-----PELTGRENIYLNGRLLGLSRKEIDEKFDEIVEFAELGDFID-QPvKTY 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 139 SGGEQQRVAIARAIVNRPKVVIADEptgnldietAL---DI------MNIFTRINERGTTIVMATHNADIVNTIRHRVIA 209
Cdd:COG1134 148 SSGMRARLAFAVATAVDPDILLVDE---------VLavgDAafqkkcLARIRELRESGRTVIFVSHSMGAVRRLCDRAIW 218
|
250
....*....|
gi 446516975 210 IEGGKIVRDE 219
Cdd:COG1134 219 LEKGRLVMDG 228
|
|
| cbiO |
PRK13638 |
energy-coupling factor ABC transporter ATP-binding protein; |
1-216 |
6.67e-20 |
|
energy-coupling factor ABC transporter ATP-binding protein;
Pssm-ID: 184198 [Multi-domain] Cd Length: 271 Bit Score: 85.44 E-value: 6.67e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 1 MIKMTNVYKEYPNGmKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIEtLAERDVPYFRRQ 80
Cdd:PRK13638 1 MLATSDLWFRYQDE-PVLKGLNLDFSLSPVTGLVGANGCGKSTLFMNLSGLLRPQKGAVLWQGKPLD-YSKRGLLALRQQ 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 81 LGVIFQDfkllPKLTVY-----ENVSFALEVIEEEPDAIRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIVNR 155
Cdd:PRK13638 79 VATVFQD----PEQQIFytdidSDIAFSLRNLGVPEAEITRRVDEALTLVDAQHFRHQPIQCLSHGQKKRVAIAGALVLQ 154
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446516975 156 PKVVIADEPTGNLDIETALDIMNIFTRINERGTTIVMATHNADIVNTIRHRVIAIEGGKIV 216
Cdd:PRK13638 155 ARYLLLDEPTAGLDPAGRTQMIAIIRRIVAQGNHVIISSHDIDLIYEISDAVYVLRQGQIL 215
|
|
| ABCC_NFT1 |
cd03369 |
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type ... |
2-216 |
9.60e-20 |
|
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type transporter 1). NFT1 belongs to the MRP (multidrug resistance-associated protein) family of ABC transporters. Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213269 [Multi-domain] Cd Length: 207 Bit Score: 83.62 E-value: 9.60e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 2 IKMTNVYKEY-PNGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLAERDVpyfRRQ 80
Cdd:cd03369 7 IEVENLSVRYaPDLPPVLKNVSFKVKAGEKIGIVGRTGAGKSTLILALFRFLEAEEGKIEIDGIDISTIPLEDL---RSS 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 81 LGVIFQDFKLLPKlTVYENvsfaLEVIEEEPDairERVTEVLglvgledRADALPSELSGGEQQRVAIARAIVNRPKVVI 160
Cdd:cd03369 84 LTIIPQDPTLFSG-TIRSN----LDPFDEYSD---EEIYGAL-------RVSEGGLNLSQGQRQLLCLARALLKRPRVLV 148
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 446516975 161 ADEPTGNLDIETALDIMNIFtRINERGTTIVMATHNadiVNTIR--HRVIAIEGGKIV 216
Cdd:cd03369 149 LDEATASIDYATDALIQKTI-REEFTNSTILTIAHR---LRTIIdyDKILVMDAGEVK 202
|
|
| modC |
PRK11144 |
molybdenum ABC transporter ATP-binding protein ModC; |
33-216 |
1.63e-19 |
|
molybdenum ABC transporter ATP-binding protein ModC;
Pssm-ID: 182993 [Multi-domain] Cd Length: 352 Bit Score: 85.31 E-value: 1.63e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 33 VVGPSGAGKSTFIKMMYREEKPSTGSINVNGltiETL--AERDV--PYFRRQLGVIFQDFKLLPKLTVYENVSFAlevIE 108
Cdd:PRK11144 29 IFGRSGAGKTSLINAISGLTRPQKGRIVLNG---RVLfdAEKGIclPPEKRRIGYVFQDARLFPHYKVRGNLRYG---MA 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 109 EEPDAIRERVTEVLGLVGLEDRadaLPSELSGGEQQRVAIARAIVNRPKVVIADEPTGNLDIETALDIMNIFTRINER-G 187
Cdd:PRK11144 103 KSMVAQFDKIVALLGIEPLLDR---YPGSLSGGEKQRVAIGRALLTAPELLLMDEPLASLDLPRKRELLPYLERLAREiN 179
|
170 180
....*....|....*....|....*....
gi 446516975 188 TTIVMATHNADIVNTIRHRVIAIEGGKIV 216
Cdd:PRK11144 180 IPILYVSHSLDEILRLADRVVVLEQGKVK 208
|
|
| PLN03211 |
PLN03211 |
ABC transporter G-25; Provisional |
18-195 |
2.01e-19 |
|
ABC transporter G-25; Provisional
Pssm-ID: 215634 [Multi-domain] Cd Length: 659 Bit Score: 86.47 E-value: 2.01e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 18 IAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMyreekpsTGSINVNGLTIETLAERDVPY--FRRQLGVIFQDFKLLPKLT 95
Cdd:PLN03211 84 LNGVTGMASPGEILAVLGPSGSGKSTLLNAL-------AGRIQGNNFTGTILANNRKPTkqILKRTGFVTQDDILYPHLT 156
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 96 VYENVSFAL------EVIEEEPDAIRERVTEVLGLVGLEDR--ADALPSELSGGEQQRVAIARAIVNRPKVVIADEPTGN 167
Cdd:PLN03211 157 VRETLVFCSllrlpkSLTKQEKILVAESVISELGLTKCENTiiGNSFIRGISGGERKRVSIAHEMLINPSLLILDEPTSG 236
|
170 180
....*....|....*....|....*...
gi 446516975 168 LDIETALDIMNIFTRINERGTTIVMATH 195
Cdd:PLN03211 237 LDATAAYRLVLTLGSLAQKGKTIVTSMH 264
|
|
| PRK14271 |
PRK14271 |
phosphate ABC transporter ATP-binding protein; Provisional |
33-218 |
2.13e-19 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172759 [Multi-domain] Cd Length: 276 Bit Score: 83.99 E-value: 2.13e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 33 VVGPSGAGKSTFIKMMYR-EEKPS----TGSINVNGLTIetLAERDVPYFRRQLGVIFQDFKLLPkLTVYENV-----SF 102
Cdd:PRK14271 52 LMGPTGSGKTTFLRTLNRmNDKVSgyrySGDVLLGGRSI--FNYRDVLEFRRRVGMLFQRPNPFP-MSIMDNVlagvrAH 128
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 103 ALEVIEEEPDAIRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIVNRPKVVIADEPTGNLDIETALDIMNIFTR 182
Cdd:PRK14271 129 KLVPRKEFRGVAQARLTEVGLWDAVKDRLSDSPFRLSGGQQQLLCLARTLAVNPEVLLLDEPTSALDPTTTEKIEEFIRS 208
|
170 180 190
....*....|....*....|....*....|....*.
gi 446516975 183 INERgTTIVMATHNADIVNTIRHRVIAIEGGKIVRD 218
Cdd:PRK14271 209 LADR-LTVIIVTHNLAQAARISDRAALFFDGRLVEE 243
|
|
| PRK14243 |
PRK14243 |
phosphate transporter ATP-binding protein; Provisional |
6-196 |
3.50e-19 |
|
phosphate transporter ATP-binding protein; Provisional
Pssm-ID: 184588 [Multi-domain] Cd Length: 264 Bit Score: 83.29 E-value: 3.50e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 6 NVYkeYPNGMkAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYR-----EEKPSTGSINVNGLTIETlAERDVPYFRRQ 80
Cdd:PRK14243 17 NVY--YGSFL-AVKNVWLDIPKNQITAFIGPSGCGKSTILRCFNRlndliPGFRVEGKVTFHGKNLYA-PDVDPVEVRRR 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 81 LGVIFQDFKLLPKlTVYENVSFALEVIEEEPDaIRERVTEVLGLVGLEDRA-DALP---SELSGGEQQRVAIARAIVNRP 156
Cdd:PRK14243 93 IGMVFQKPNPFPK-SIYDNIAYGARINGYKGD-MDELVERSLRQAALWDEVkDKLKqsgLSLSGGQQQRLCIARAIAVQP 170
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 446516975 157 KVVIADEPTGNLDIETALDIMNIFTRINERgTTIVMATHN 196
Cdd:PRK14243 171 EVILMDEPCSALDPISTLRIEELMHELKEQ-YTIIIVTHN 209
|
|
| PRK11147 |
PRK11147 |
ABC transporter ATPase component; Reviewed |
25-216 |
6.04e-19 |
|
ABC transporter ATPase component; Reviewed
Pssm-ID: 236861 [Multi-domain] Cd Length: 635 Bit Score: 85.00 E-value: 6.04e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 25 IKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLAERDVPyfRRQLGVIFqDF------KLLPKLTVYE 98
Cdd:PRK11147 26 IEDNERVCLVGRNGAGKSTLMKILNGEVLLDDGRIIYEQDLIVARLQQDPP--RNVEGTVY-DFvaegieEQAEYLKRYH 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 99 NVSfalEVIEEEPD--------AIRE------------RVTEVLGLVGLEdrADALPSELSGGEQQRVAIARAIVNRPKV 158
Cdd:PRK11147 103 DIS---HLVETDPSeknlnelaKLQEqldhhnlwqlenRINEVLAQLGLD--PDAALSSLSGGWLRKAALGRALVSNPDV 177
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 446516975 159 VIADEPTGNLDIETaLDIMNIFTRiNERGtTIVMATHNADIVNTIRHRVIAIEGGKIV 216
Cdd:PRK11147 178 LLLDEPTNHLDIET-IEWLEGFLK-TFQG-SIIFISHDRSFIRNMATRIVDLDRGKLV 232
|
|
| PRK10762 |
PRK10762 |
D-ribose transporter ATP binding protein; Provisional |
1-195 |
6.07e-19 |
|
D-ribose transporter ATP binding protein; Provisional
Pssm-ID: 236755 [Multi-domain] Cd Length: 501 Bit Score: 84.67 E-value: 6.07e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 1 MIKMTNVYKEYPnGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLAERDvpyfrRQ 80
Cdd:PRK10762 4 LLQLKGIDKAFP-GVKALSGAALNVYPGRVMALVGENGAGKSTMMKVLTGIYTRDAGSILYLGKEVTFNGPKS-----SQ 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 81 ---LGVIFQDFKLLPKLTVYENVSFALEVIE-----------EEPDAIRERVtevlglvGLEDRADALPSELSGGEQQRV 146
Cdd:PRK10762 78 eagIGIIHQELNLIPQLTIAENIFLGREFVNrfgridwkkmyAEADKLLARL-------NLRFSSDKLVGELSIGEQQMV 150
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 446516975 147 AIARAIVNRPKVVIADEPTGNL-DIETAldimNIFTRINE---RGTTIVMATH 195
Cdd:PRK10762 151 EIAKVLSFESKVIIMDEPTDALtDTETE----SLFRVIRElksQGRGIVYISH 199
|
|
| PRK15134 |
PRK15134 |
microcin C ABC transporter ATP-binding protein YejF; Provisional |
18-216 |
7.30e-19 |
|
microcin C ABC transporter ATP-binding protein YejF; Provisional
Pssm-ID: 237917 [Multi-domain] Cd Length: 529 Bit Score: 84.37 E-value: 7.30e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 18 IAGLTVNIKQGEFVYVVGPSGAGKS-TFIKMMYREEKPS----TGSINVNGltiETLAERDVPYFRR----QLGVIFQD- 87
Cdd:PRK15134 25 VNDVSLQIEAGETLALVGESGSGKSvTALSILRLLPSPPvvypSGDIRFHG---ESLLHASEQTLRGvrgnKIAMIFQEp 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 88 -FKLLPKLTV----YENVSFALEVIEEepdAIRERVTEVLGLVGLEDRADAL---PSELSGGEQQRVAIARAIVNRPKVV 159
Cdd:PRK15134 102 mVSLNPLHTLekqlYEVLSLHRGMRRE---AARGEILNCLDRVGIRQAAKRLtdyPHQLSGGERQRVMIAMALLTRPELL 178
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 446516975 160 IADEPTGNLDIETALDIMNIFTRI-NERGTTIVMATHNADIVNTIRHRVIAIEGGKIV 216
Cdd:PRK15134 179 IADEPTTALDVSVQAQILQLLRELqQELNMGLLFITHNLSIVRKLADRVAVMQNGRCV 236
|
|
| xylG |
TIGR02633 |
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ... |
1-216 |
1.36e-18 |
|
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]
Pssm-ID: 131681 [Multi-domain] Cd Length: 500 Bit Score: 83.72 E-value: 1.36e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 1 MIKMTNVYKEYpNGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPST--GSINVNGLTIETLAERDVPyfR 78
Cdd:TIGR02633 1 LLEMKGIVKTF-GGVKALDGIDLEVRPGECVGLCGENGAGKSTLMKILSGVYPHGTwdGEIYWSGSPLKASNIRDTE--R 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 79 RQLGVIFQDFKLLPKLTVYENVSFALEVIEE----EPDAIRERVTEVLGLVGLEDRADALP-SELSGGEQQRVAIARAIV 153
Cdd:TIGR02633 78 AGIVIIHQELTLVPELSVAENIFLGNEITLPggrmAYNAMYLRAKNLLRELQLDADNVTRPvGDYGGGQQQLVEIAKALN 157
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446516975 154 NRPKVVIADEPTGNLDIETALDIMNIFTRINERGTTIVMATHNADIVNTIRHRVIAIEGGKIV 216
Cdd:TIGR02633 158 KQARLLILDEPSSSLTEKETEILLDIIRDLKAHGVACVYISHKLNEVKAVCDTICVIRDGQHV 220
|
|
| ABCF_EF-3 |
cd03221 |
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is ... |
2-214 |
3.58e-18 |
|
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is a cytosolic protein required by fungal ribosomes for in vitro protein synthesis and for in vivo growth. EF-3 stimulates the binding of the EF-1: GTP: aa-tRNA ternary complex to the ribosomal A site by facilitated release of the deacylated tRNA from the E site. The reaction requires ATP hydrolysis. EF-3 contains two ATP nucleotide binding sequence (NBS) motifs. NBSI is sufficient for the intrinsic ATPase activity. NBSII is essential for the ribosome-stimulated functions.
Pssm-ID: 213188 [Multi-domain] Cd Length: 144 Bit Score: 77.87 E-value: 3.58e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 2 IKMTNVYKEYPNGmKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGsinvnglTIETLAERDVPYFrrql 81
Cdd:cd03221 1 IELENLSKTYGGK-LLLKDISLTINPGDRIGLVGRNGAGKSTLLKLIAGELEPDEG-------IVTWGSTVKIGYF---- 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 82 gvifqdfkllpkltvyenvsfalevieeepdairervtevlglvgledradalpSELSGGEQQRVAIARAIVNRPKVVIA 161
Cdd:cd03221 69 ------------------------------------------------------EQLSGGEKMRLALAKLLLENPNLLLL 94
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 446516975 162 DEPTGNLDIETaLDIMNIFtrINERGTTIVMATHNADIVNTIRHRVIAIEGGK 214
Cdd:cd03221 95 DEPTNHLDLES-IEALEEA--LKEYPGTVILVSHDRYFLDQVATKIIELEDGK 144
|
|
| PRK10790 |
PRK10790 |
SmdB family multidrug efflux ABC transporter permease/ATP-binding protein; |
2-214 |
5.01e-18 |
|
SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;
Pssm-ID: 182733 [Multi-domain] Cd Length: 592 Bit Score: 82.07 E-value: 5.01e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 2 IKMTNVYKEYPNGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLAERdvpYFRRQL 81
Cdd:PRK10790 341 IDIDNVSFAYRDDNLVLQNINLSVPSRGFVALVGHTGSGKSTLASLLMGYYPLTEGEIRLDGRPLSSLSHS---VLRQGV 417
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 82 GVIFQDFKLLPKlTVYENVSFALEVIEEepdaireRVTEVLGLVGLEDRADALP-----------SELSGGEQQRVAIAR 150
Cdd:PRK10790 418 AMVQQDPVVLAD-TFLANVTLGRDISEE-------QVWQALETVQLAELARSLPdglytplgeqgNNLSVGQKQLLALAR 489
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446516975 151 AIVNRPKVVIADEPTGNLDIETALDIMNIFTRINERGTTIVMATHNADIV--NTIR--HRVIAIEGGK 214
Cdd:PRK10790 490 VLVQTPQILILDEATANIDSGTEQAIQQALAAVREHTTLVVIAHRLSTIVeaDTILvlHRGQAVEQGT 557
|
|
| ABC_RNaseL_inhibitor_domain2 |
cd03237 |
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ... |
11-212 |
5.02e-18 |
|
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity of more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.
Pssm-ID: 213204 [Multi-domain] Cd Length: 246 Bit Score: 79.76 E-value: 5.02e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 11 YPNGMKAIAGLTVNIKQGEF-----VYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIEtlaerdvpyFRRQlgVIF 85
Cdd:cd03237 3 YPTMKKTLGEFTLEVEGGSIsesevIGILGPNGIGKTTFIKMLAGVLKPDEGDIEIELDTVS---------YKPQ--YIK 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 86 QDFKLlpklTVYENVSFALEVIEEEPDAIrervTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIVNRPKVVIADEPT 165
Cdd:cd03237 72 ADYEG----TVRDLLSSITKDFYTHPYFK----TEIAKPLQIEQILDREVPELSGGELQRVAIAACLSKDADIYLLDEPS 143
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 446516975 166 GNLDIETALDIMNIFTRI--NERGTTIV------MATHNADivntirhRVIAIEG 212
Cdd:cd03237 144 AYLDVEQRLMASKVIRRFaeNNEKTAFVvehdiiMIDYLAD-------RLIVFEG 191
|
|
| livG |
PRK11300 |
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional |
14-214 |
5.04e-18 |
|
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional
Pssm-ID: 183080 [Multi-domain] Cd Length: 255 Bit Score: 80.03 E-value: 5.04e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 14 GMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLAERDVPyfrrQLGVI--FQDFKLL 91
Cdd:PRK11300 17 GLLAVNNVNLEVREQEIVSLIGPNGAGKTTVFNCLTGFYKPTGGTILLRGQHIEGLPGHQIA----RMGVVrtFQHVRLF 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 92 PKLTVYENVSFA----LEV------------IEEEPDAIrERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIVNR 155
Cdd:PRK11300 93 REMTVIENLLVAqhqqLKTglfsgllktpafRRAESEAL-DRAATWLERVGLLEHANRQAGNLAYGQQRRLEIARCMVTQ 171
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 156 PKVVIADEPTGNLDIETALDIMNIFTRI-NERGTTIVMATHNADIVNTIRHRVIAIEGGK 214
Cdd:PRK11300 172 PEILMLDEPAAGLNPKETKELDELIAELrNEHNVTVLLIEHDMKLVMGISDRIYVVNQGT 231
|
|
| SufC |
COG0396 |
Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, ... |
20-228 |
3.13e-17 |
|
Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440165 [Multi-domain] Cd Length: 245 Bit Score: 77.41 E-value: 3.13e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 20 GLTVNIKQGEFVYVVGPSGAGKSTFIK-MMYREE-KPSTGSINVNG-----LTIEtlaERdvpyFRRQLGVIFQDFKLLP 92
Cdd:COG0396 18 GVNLTIKPGEVHAIMGPNGSGKSTLAKvLMGHPKyEVTSGSILLDGedileLSPD---ER----ARAGIFLAFQYPVEIP 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 93 KLTVYENVSFAL-EVIEEEPDAI--RERVTEVLGLVGLEDraDALPSEL----SGGEQQRVAIARAIVNRPKVVIADEPT 165
Cdd:COG0396 91 GVSVSNFLRTALnARRGEELSARefLKLLKEKMKELGLDE--DFLDRYVnegfSGGEKKRNEILQMLLLEPKLAILDETD 168
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446516975 166 GNLDIEtALDIM-NIFTRINERGTTIVMATHNADIVNTIR-HRVIAIEGGKIVR-------DEIEgGYGYEG 228
Cdd:COG0396 169 SGLDID-ALRIVaEGVNKLRSPDRGILIITHYQRILDYIKpDFVHVLVDGRIVKsggkelaLELE-EEGYDW 238
|
|
| araG |
PRK11288 |
L-arabinose ABC transporter ATP-binding protein AraG; |
6-217 |
3.88e-17 |
|
L-arabinose ABC transporter ATP-binding protein AraG;
Pssm-ID: 183077 [Multi-domain] Cd Length: 501 Bit Score: 79.57 E-value: 3.88e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 6 NVYKEYPnGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLAERDVpyFRRQLGVIF 85
Cdd:PRK11288 9 GIGKTFP-GVKALDDISFDCRAGQVHALMGENGAGKSTLLKILSGNYQPDAGSILIDGQEMRFASTTAA--LAAGVAIIY 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 86 QDFKLLPKLTVYENVSF-----ALEVIEEEpdAIRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIVNRPKVVI 160
Cdd:PRK11288 86 QELHLVPEMTVAENLYLgqlphKGGIVNRR--LLNYEAREQLEHLGVDIDPDTPLKYLSIGQRQMVEIAKALARNARVIA 163
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 161 ADEPTGNLdieTALDIMNIFTRINE---RGTTIVMATHNADIVNTIRHRVIAIEGGKIVR 217
Cdd:PRK11288 164 FDEPTSSL---SAREIEQLFRVIRElraEGRVILYVSHRMEEIFALCDAITVFKDGRYVA 220
|
|
| PRK13549 |
PRK13549 |
xylose transporter ATP-binding subunit; Provisional |
1-214 |
9.80e-17 |
|
xylose transporter ATP-binding subunit; Provisional
Pssm-ID: 184134 [Multi-domain] Cd Length: 506 Bit Score: 78.43 E-value: 9.80e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 1 MIKMTNVYKEYPnGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMM---YreekPS---TGSINVNGLTIETLAERDV 74
Cdd:PRK13549 5 LLEMKNITKTFG-GVKALDNVSLKVRAGEIVSLCGENGAGKSTLMKVLsgvY----PHgtyEGEIIFEGEELQASNIRDT 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 75 PyfRRQLGVIFQDFKLLPKLTVYENVSFALEVIEE---EPDAIRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARA 151
Cdd:PRK13549 80 E--RAGIAIIHQELALVKELSVLENIFLGNEITPGgimDYDAMYLRAQKLLAQLKLDINPATPVGNLGLGQQQLVEIAKA 157
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446516975 152 IVNRPKVVIADEPTGNL-DIETALdIMNIFTRINERGTTIVMATHNADIVNTIRHRVIAIEGGK 214
Cdd:PRK13549 158 LNKQARLLILDEPTASLtESETAV-LLDIIRDLKAHGIACIYISHKLNEVKAISDTICVIRDGR 220
|
|
| ABC_ABC_ChvD |
TIGR03719 |
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ... |
2-172 |
3.68e-16 |
|
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.
Pssm-ID: 274744 [Multi-domain] Cd Length: 552 Bit Score: 76.51 E-value: 3.68e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 2 IKMTNVYKEYPNGMkAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVnGLTIetlaerdvpyfrrQL 81
Cdd:TIGR03719 323 IEAENLTKAFGDKL-LIDDLSFKLPPGGIVGVIGPNGAGKSTLFRMITGQEQPDSGTIEI-GETV-------------KL 387
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 82 GVIFQDFKLL-PKLTVYENVSFALEVIEeepdairervtevLGLVGLEDRA------------DALPSELSGGEQQRVAI 148
Cdd:TIGR03719 388 AYVDQSRDALdPNKTVWEEISGGLDIIK-------------LGKREIPSRAyvgrfnfkgsdqQKKVGQLSGGERNRVHL 454
|
170 180
....*....|....*....|....
gi 446516975 149 ARAIVNRPKVVIADEPTGNLDIET 172
Cdd:TIGR03719 455 AKTLKSGGNVLLLDEPTNDLDVET 478
|
|
| PRK15056 |
PRK15056 |
manganese/iron ABC transporter ATP-binding protein; |
2-212 |
1.80e-15 |
|
manganese/iron ABC transporter ATP-binding protein;
Pssm-ID: 185016 [Multi-domain] Cd Length: 272 Bit Score: 73.38 E-value: 1.80e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 2 IKMTNVYKEYPNGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLAERDVPYFRRQL 81
Cdd:PRK15056 7 IVVNDVTVTWRNGHTALRDASFTVPGGSIAALVGVNGSGKSTLFKALMGFVRLASGKISILGQPTRQALQKNLVAYVPQS 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 82 GVIFQDFKLLPKLTVYENVSFALEVIEEEPDAIRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIVNRPKVVIA 161
Cdd:PRK15056 87 EEVDWSFPVLVEDVVMMGRYGHMGWLRRAKKRDRQIVTAALARVDMVEFRHRQIGELSGGQKKRVFLARAIAQQGQVILL 166
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 446516975 162 DEPTGNLDIETALDIMNIFTRINERGTTIVMATHNADIVNTIRHRVIAIEG 212
Cdd:PRK15056 167 DEPFTGVDVKTEARIISLLRELRDEGKTMLVSTHNLGSVTEFCDYTVMVKG 217
|
|
| ABCG_PDR_domain1 |
cd03233 |
First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette ... |
13-216 |
2.01e-15 |
|
First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213200 [Multi-domain] Cd Length: 202 Bit Score: 71.91 E-value: 2.01e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 13 NGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMM--YREEKPS-TGSINVNGLTIETLAErdvpYFRRQlgVIF---Q 86
Cdd:cd03233 18 SKIPILKDFSGVVKPGEMVLVLGRPGSGCSTLLKALanRTEGNVSvEGDIHYNGIPYKEFAE----KYPGE--IIYvseE 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 87 DFKLlPKLTVYENVSFALEVieeepdairervtevlglvgledRADALPSELSGGEQQRVAIARAIVNRPKVVIADEPTG 166
Cdd:cd03233 92 DVHF-PTLTVRETLDFALRC-----------------------KGNEFVRGISGGERKRVSIAEALVSRASVLCWDNSTR 147
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 446516975 167 NLDIETALDIMNI---FTRInERGTTIVMATHNADIVNTIRHRVIAIEGGKIV 216
Cdd:cd03233 148 GLDSSTALEILKCirtMADV-LKTTTFVSLYQASDEIYDLFDKVLVLYEGRQI 199
|
|
| ABC_ABC_ChvD |
TIGR03719 |
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ... |
4-172 |
2.27e-15 |
|
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.
Pssm-ID: 274744 [Multi-domain] Cd Length: 552 Bit Score: 74.20 E-value: 2.27e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 4 MTNVYKEYPNGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGsinvngltiETLAERDVpyfrrQLGV 83
Cdd:TIGR03719 7 MNRVSKVVPPKKEILKDISLSFFPGAKIGVLGLNGAGKSTLLRIMAGVDKDFNG---------EARPQPGI-----KVGY 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 84 IFQDFKLLPKLTVYENVSFALEVIEE-------------EPDA-----IRE--RVTEVLGLVG-------LEDRADAL-- 134
Cdd:TIGR03719 73 LPQEPQLDPTKTVRENVEEGVAEIKDaldrfneisakyaEPDAdfdklAAEqaELQEIIDAADawdldsqLEIAMDALrc 152
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 446516975 135 P------SELSGGEQQRVAIARAIVNRPKVVIADEPTGNLDIET 172
Cdd:TIGR03719 153 PpwdadvTKLSGGERRRVALCRLLLSKPDMLLLDEPTNHLDAES 196
|
|
| PTZ00265 |
PTZ00265 |
multidrug resistance protein (mdr1); Provisional |
21-205 |
2.37e-15 |
|
multidrug resistance protein (mdr1); Provisional
Pssm-ID: 240339 [Multi-domain] Cd Length: 1466 Bit Score: 74.68 E-value: 2.37e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 21 LTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNglTIETLAERDVPYFRRQLGVIFQDfKLLPKLTVYENV 100
Cdd:PTZ00265 404 LNFTLTEGKTYAFVGESGCGKSTILKLIERLYDPTEGDIIIN--DSHNLKDINLKWWRSKIGVVSQD-PLLFSNSIKNNI 480
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 101 SFAL----------EVIEEEPDAIRE-----------------------------------------RVTEVLGLVGLED 129
Cdd:PTZ00265 481 KYSLyslkdlealsNYYNEDGNDSQEnknkrnscrakcagdlndmsnttdsneliemrknyqtikdsEVVDVSKKVLIHD 560
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 130 RADALP-----------SELSGGEQQRVAIARAIVNRPKVVIADEPTGNLDIETALDIMNIFTRI--NERGTTIVMATHn 196
Cdd:PTZ00265 561 FVSALPdkyetlvgsnaSKLSGGQKQRISIARAIIRNPKILILDEATSSLDNKSEYLVQKTINNLkgNENRITIIIAHR- 639
|
....*....
gi 446516975 197 adiVNTIRH 205
Cdd:PTZ00265 640 ---LSTIRY 645
|
|
| PRK15093 |
PRK15093 |
peptide ABC transporter ATP-binding protein SapD; |
15-216 |
2.44e-15 |
|
peptide ABC transporter ATP-binding protein SapD;
Pssm-ID: 185049 [Multi-domain] Cd Length: 330 Bit Score: 73.68 E-value: 2.44e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 15 MKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKP----STGSINVNGLTIETLAERDvpyfRRQL-----GVIF 85
Cdd:PRK15093 20 VKAVDRVSMTLTEGEIRGLVGESGSGKSLIAKAICGVTKDnwrvTADRMRFDDIDLLRLSPRE----RRKLvghnvSMIF 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 86 QDfkllPKLTVYENVSFALEVIEEEPDAI------------RERVTEVLGLVGLEDRADAL---PSELSGGEQQRVAIAR 150
Cdd:PRK15093 96 QE----PQSCLDPSERVGRQLMQNIPGWTykgrwwqrfgwrKRRAIELLHRVGIKDHKDAMrsfPYELTEGECQKVMIAI 171
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446516975 151 AIVNRPKVVIADEPTGNLDIETALDIMNIFTRINER-GTTIVMATHNADIVNTIRHRVIAIEGGKIV 216
Cdd:PRK15093 172 ALANQPRLLIADEPTNAMEPTTQAQIFRLLTRLNQNnNTTILLISHDLQMLSQWADKINVLYCGQTV 238
|
|
| PRK13543 |
PRK13543 |
heme ABC exporter ATP-binding protein CcmA; |
21-212 |
3.46e-15 |
|
heme ABC exporter ATP-binding protein CcmA;
Pssm-ID: 184129 [Multi-domain] Cd Length: 214 Bit Score: 71.42 E-value: 3.46e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 21 LTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETlAERDvpyfrRQLGVIFQDFKLLPKLTVYENV 100
Cdd:PRK13543 30 LDFHVDAGEALLVQGDNGAGKTTLLRVLAGLLHVESGQIQIDGKTATR-GDRS-----RFMAYLGHLPGLKADLSTLENL 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 101 SFALEVIEEEPdaiRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIVNRPKVVIADEPTGNLDIE--TALDIMn 178
Cdd:PRK13543 104 HFLCGLHGRRA---KQMPGSALAIVGLAGYEDTLVRQLSAGQKKRLALARLWLSPAPLWLLDEPYANLDLEgiTLVNRM- 179
|
170 180 190
....*....|....*....|....*....|....
gi 446516975 179 IFTRINERGTTIVmATHNADIVNTIRHRVIAIEG 212
Cdd:PRK13543 180 ISAHLRGGGAALV-TTHGAYAAPPVRTRMLTLEA 212
|
|
| PRK11176 |
PRK11176 |
lipid A ABC transporter ATP-binding protein/permease MsbA; |
2-216 |
7.41e-15 |
|
lipid A ABC transporter ATP-binding protein/permease MsbA;
Pssm-ID: 183016 [Multi-domain] Cd Length: 582 Bit Score: 72.74 E-value: 7.41e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 2 IKMTNVYKEYPNGMK-AIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIE--TLAErdvpyFR 78
Cdd:PRK11176 342 IEFRNVTFTYPGKEVpALRNINFKIPAGKTVALVGRSGSGKSTIANLLTRFYDIDEGEILLDGHDLRdyTLAS-----LR 416
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 79 RQLGVIFQDFKLLPKlTVYENVSFALEVIEEEPDAIRE-RVTEVLGLV-GLEDRADALPSE----LSGGEQQRVAIARAI 152
Cdd:PRK11176 417 NQVALVSQNVHLFND-TIANNIAYARTEQYSREQIEEAaRMAYAMDFInKMDNGLDTVIGEngvlLSGGQRQRIAIARAL 495
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 153 VNRPKVVIADEPTGNLDIETALDIMNIFTRINERGTTIVMAtH------NADivntirhRVIAIEGGKIV 216
Cdd:PRK11176 496 LRDSPILILDEATSALDTESERAIQAALDELQKNRTSLVIA-HrlstieKAD-------EILVVEDGEIV 557
|
|
| ABCG_PDR_domain2 |
cd03232 |
Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding ... |
25-216 |
9.92e-15 |
|
Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213199 [Multi-domain] Cd Length: 192 Bit Score: 69.96 E-value: 9.92e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 25 IKQGEFVYVVGPSGAGKSTFIKMM-YREEKPS-TGSINVNGLTIEtlaerdvPYFRRQLGVIFQDFKLLPKLTVYENVSF 102
Cdd:cd03232 30 VKPGTLTALMGESGAGKTTLLDVLaGRKTAGViTGEILINGRPLD-------KNFQRSTGYVEQQDVHSPNLTVREALRF 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 103 AlevieeepdairervtevlglvgledradALPSELSGGEQQRVAIARAIVNRPKVVIADEPTGNLDIETALDIMNIFTR 182
Cdd:cd03232 103 S-----------------------------ALLRGLSVEQRKRLTIGVELAAKPSILFLDEPTSGLDSQAAYNIVRFLKK 153
|
170 180 190
....*....|....*....|....*....|....*.
gi 446516975 183 INERGTTIVMATH--NADIVNTIRHRVIAIEGGKIV 216
Cdd:cd03232 154 LADSGQAILCTIHqpSASIFEKFDRLLLLKRGGKTV 189
|
|
| 3a01205 |
TIGR00956 |
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other] |
25-216 |
1.27e-14 |
|
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273362 [Multi-domain] Cd Length: 1394 Bit Score: 72.45 E-value: 1.27e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 25 IKQGEFVYVVGPSGAGKSTFIKMM----YREEKPSTGSINVNGLTIETLaerdVPYFRRQLGVIFQDFKLLPKLTVYENV 100
Cdd:TIGR00956 84 IKPGELTVVLGRPGSGCSTLLKTIasntDGFHIGVEGVITYDGITPEEI----KKHYRGDVVYNAETDVHFPHLTVGETL 159
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 101 SFA--LEVIEEEPDAI-----RERVTEV----LGL-------VGledraDALPSELSGGEQQRVAIARAIVNRPKVVIAD 162
Cdd:TIGR00956 160 DFAarCKTPQNRPDGVsreeyAKHIADVymatYGLshtrntkVG-----NDFVRGVSGGERKRVSIAEASLGGAKIQCWD 234
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 446516975 163 EPTGNLDIETALDIMN-IFTRINERGTTIVMATHNA--DIVNTIrHRVIAIEGGKIV 216
Cdd:TIGR00956 235 NATRGLDSATALEFIRaLKTSANILDTTPLVAIYQCsqDAYELF-DKVIVLYEGYQI 290
|
|
| Rli1 |
COG1245 |
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ... |
3-212 |
1.55e-14 |
|
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];
Pssm-ID: 440858 [Multi-domain] Cd Length: 592 Bit Score: 72.12 E-value: 1.55e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 3 KMTNVYKEYPNGMKAIAG--LTVN---IKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNgLTIEtlaerdvpyF 77
Cdd:COG1245 336 KEEETLVEYPDLTKSYGGfsLEVEggeIREGEVLGIVGPNGIGKTTFAKILAGVLKPDEGEVDED-LKIS---------Y 405
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 78 RRQLGVIFQDfkllpkLTVYENVSfalevieeepDAIRERV------TEVLGLVGLEDRADALPSELSGGEQQRVAIARA 151
Cdd:COG1245 406 KPQYISPDYD------GTVEEFLR----------SANTDDFgssyykTEIIKPLGLEKLLDKNVKDLSGGELQRVAIAAC 469
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446516975 152 IVNRPKVVIADEPTGNLDIETALDIMNIFTRINE-RGTTIVMATHNADIVNTIRHRVIAIEG 212
Cdd:COG1245 470 LSRDADLYLLDEPSAHLDVEQRLAVAKAIRRFAEnRGKTAMVVDHDIYLIDYISDRLMVFEG 531
|
|
| MglA |
COG1129 |
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; |
25-223 |
1.57e-14 |
|
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440745 [Multi-domain] Cd Length: 497 Bit Score: 71.97 E-value: 1.57e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 25 IKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLAERD--------VPYFRRQLGvifqdfkLLPKLTV 96
Cdd:COG1129 275 VRAGEILGIAGLVGAGRTELARALFGADPADSGEIRLDGKPVRIRSPRDairagiayVPEDRKGEG-------LVLDLSI 347
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 97 YENVSFAleVIEE-------EPDAIRERVTEVLGLVGLE-DRADALPSELSGGEQQRVAIARAIVNRPKVVIADEPTGNL 168
Cdd:COG1129 348 RENITLA--SLDRlsrggllDRRRERALAEEYIKRLRIKtPSPEQPVGNLSGGNQQKVVLAKWLATDPKVLILDEPTRGI 425
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446516975 169 DIETALDIMNIFTRINERGTTIVMAT-------HNADivntirhRVIAIEGGKIVRdEIEGG 223
Cdd:COG1129 426 DVGAKAEIYRLIRELAAEGKAVIVISselpellGLSD-------RILVMREGRIVG-ELDRE 479
|
|
| znuC |
PRK09544 |
high-affinity zinc transporter ATPase; Reviewed |
1-200 |
2.06e-14 |
|
high-affinity zinc transporter ATPase; Reviewed
Pssm-ID: 181939 [Multi-domain] Cd Length: 251 Bit Score: 70.14 E-value: 2.06e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 1 MIKMTNVYKEYPNgMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSInvngltietlaERDVPYfrrQ 80
Cdd:PRK09544 4 LVSLENVSVSFGQ-RRVLSDVSLELKPGKILTLLGPNGAGKSTLVRVVLGLVAPDEGVI-----------KRNGKL---R 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 81 LGVIFQDFKLLPKLTVyeNVSFALEVieeEPDAIRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIVNRPKVVI 160
Cdd:PRK09544 69 IGYVPQKLYLDTTLPL--TVNRFLRL---RPGTKKEDILPALKRVQAGHLIDAPMQKLSGGETQRVLLARALLNRPQLLV 143
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 446516975 161 ADEPTGNLDIETALDIMNIFTRI-NERGTTIVMATHNADIV 200
Cdd:PRK09544 144 LDEPTQGVDVNGQVALYDLIDQLrRELDCAVLMVSHDLHLV 184
|
|
| PRK10261 |
PRK10261 |
glutathione transporter ATP-binding protein; Provisional |
17-216 |
2.18e-14 |
|
glutathione transporter ATP-binding protein; Provisional
Pssm-ID: 182342 [Multi-domain] Cd Length: 623 Bit Score: 71.42 E-value: 2.18e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 17 AIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIE-------TLAERDVPYFRR----QLGVIF 85
Cdd:PRK10261 31 AVRNLSFSLQRGETLAIVGESGSGKSVTALALMRLLEQAGGLVQCDKMLLRrrsrqviELSEQSAAQMRHvrgaDMAMIF 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 86 QD--FKLLPKLTVYENVSFALEVIE----EEPDAIRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIVNRPKVV 159
Cdd:PRK10261 111 QEpmTSLNPVFTVGEQIAESIRLHQgasrEEAMVEAKRMLDQVRIPEAQTILSRYPHQLSGGMRQRVMIAMALSCRPAVL 190
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 446516975 160 IADEPTGNLDIETALDIMNIFTRIN-ERGTTIVMATHNADIVNTIRHRVIAIEGGKIV 216
Cdd:PRK10261 191 IADEPTTALDVTIQAQILQLIKVLQkEMSMGVIFITHDMGVVAEIADRVLVMYQGEAV 248
|
|
| ABC2_perm_RbbA |
NF033858 |
ribosome-associated ATPase/putative transporter RbbA; |
25-165 |
2.63e-14 |
|
ribosome-associated ATPase/putative transporter RbbA;
Pssm-ID: 468210 [Multi-domain] Cd Length: 907 Bit Score: 71.31 E-value: 2.63e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 25 IKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGS-------INVNGltIETlaerdvpyfRRQLGVIFQDFKLLPKLTVY 97
Cdd:NF033858 289 IRRGEIFGFLGSNGCGKSTTMKMLTGLLPASEGEawlfgqpVDAGD--IAT---------RRRVGYMSQAFSLYGELTVR 357
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446516975 98 ENVS-----FALEvieeePDAIRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIVNRPKVVIADEPT 165
Cdd:NF033858 358 QNLElharlFHLP-----AAEIAARVAEMLERFDLADVADALPDSLPLGIRQRLSLAVAVIHKPELLILDEPT 425
|
|
| PRK13409 |
PRK13409 |
ribosome biogenesis/translation initiation ATPase RLI; |
7-212 |
2.68e-14 |
|
ribosome biogenesis/translation initiation ATPase RLI;
Pssm-ID: 184037 [Multi-domain] Cd Length: 590 Bit Score: 71.38 E-value: 2.68e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 7 VYKEYPNGMKAIAG--LTVN---IKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNgLTIEtlaerdvpyFRRQL 81
Cdd:PRK13409 339 TLVEYPDLTKKLGDfsLEVEggeIYEGEVIGIVGPNGIGKTTFAKLLAGVLKPDEGEVDPE-LKIS---------YKPQY 408
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 82 gvIFQDFkllpKLTVYENVSFALEVIEEEPdaIRERVTEVLGLVGLEDRAdalPSELSGGEQQRVAIARAIVNRPKVVIA 161
Cdd:PRK13409 409 --IKPDY----DGTVEDLLRSITDDLGSSY--YKSEIIKPLQLERLLDKN---VKDLSGGELQRVAIAACLSRDADLYLL 477
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 446516975 162 DEPTGNLDIETALDIMNIFTRINE-RGTTIVMATHNADIVNTIRHRVIAIEG 212
Cdd:PRK13409 478 DEPSAHLDVEQRLAVAKAIRRIAEeREATALVVDHDIYMIDYISDRLMVFEG 529
|
|
| ABCC_SUR1_N |
cd03290 |
ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The ... |
2-195 |
4.15e-14 |
|
ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The sulfonylurea receptor SUR is an ATP transporter of the ABCC/MRP family with tandem ATPase binding domains. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.
Pssm-ID: 213257 [Multi-domain] Cd Length: 218 Bit Score: 68.51 E-value: 4.15e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 2 IKMTNVYKEYPNGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSIN-VNGLTIETLAERDVPYFRRQ 80
Cdd:cd03290 1 VQVTNGYFSWGSGLATLSNINIRIPTGQLTMIVGQVGCGKSSLLLAILGEMQTLEGKVHwSNKNESEPSFEATRSRNRYS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 81 LGVIFQDFKLLpKLTVYENVSFalevieEEPDAiRERVTEVLGLVGLEDRADALPS-----------ELSGGEQQRVAIA 149
Cdd:cd03290 81 VAYAAQKPWLL-NATVEENITF------GSPFN-KQRYKAVTDACSLQPDIDLLPFgdqteigergiNLSGGQRQRICVA 152
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 446516975 150 RAIVNRPKVVIADEPTGNLDIETALDIMN--IFTRINERGTTIVMATH 195
Cdd:cd03290 153 RALYQNTNIVFLDDPFSALDIHLSDHLMQegILKFLQDDKRTLVLVTH 200
|
|
| PRK10762 |
PRK10762 |
D-ribose transporter ATP binding protein; Provisional |
24-215 |
4.17e-14 |
|
D-ribose transporter ATP binding protein; Provisional
Pssm-ID: 236755 [Multi-domain] Cd Length: 501 Bit Score: 70.80 E-value: 4.17e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 24 NIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLAERDVpyFRRQLGVIFQDFK---LLPKLTVYENV 100
Cdd:PRK10762 274 TLRKGEILGVSGLMGAGRTELMKVLYGALPRTSGYVTLDGHEVVTRSPQDG--LANGIVYISEDRKrdgLVLGMSVKENM 351
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 101 SF-ALEVIEEEPDAIR--ERVTEVLGLVGLED----RADALPSELSGGEQQRVAIARAIVNRPKVVIADEPTGNLDIETA 173
Cdd:PRK10762 352 SLtALRYFSRAGGSLKhaDEQQAVSDFIRLFNiktpSMEQAIGLLSGGNQQKVAIARGLMTRPKVLILDEPTRGVDVGAK 431
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 446516975 174 LDIMNIFTRINERGTTIVMATHNADIVNTIRHRVIAIEGGKI 215
Cdd:PRK10762 432 KEIYQLINQFKAEGLSIILVSSEMPEVLGMSDRILVMHEGRI 473
|
|
| PTZ00265 |
PTZ00265 |
multidrug resistance protein (mdr1); Provisional |
33-216 |
4.39e-14 |
|
multidrug resistance protein (mdr1); Provisional
Pssm-ID: 240339 [Multi-domain] Cd Length: 1466 Bit Score: 70.83 E-value: 4.39e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 33 VVGPSGAGKSTFIKMMYR----------------------------EEKPSTGSINVN--GLTIETLAERDVPYFR---- 78
Cdd:PTZ00265 1199 IVGETGSGKSTVMSLLMRfydlkndhhivfknehtndmtneqdyqgDEEQNVGMKNVNefSLTKEGGSGEDSTVFKnsgk 1278
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 79 ----------------RQLGVIFQDFKLLPKLTVYENVSFALEvieeepDAIRERVTEVLGLVGLEDRADALPSE----- 137
Cdd:PTZ00265 1279 illdgvdicdynlkdlRNLFSIVSQEPMLFNMSIYENIKFGKE------DATREDVKRACKFAAIDEFIESLPNKydtnv 1352
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 138 ------LSGGEQQRVAIARAIVNRPKVVIADEPTGNLDIETaldimnifTRINERgtTIVMATHNAD-IVNTIRHRVIAI 210
Cdd:PTZ00265 1353 gpygksLSGGQKQRIAIARALLREPKILLLDEATSSLDSNS--------EKLIEK--TIVDIKDKADkTIITIAHRIASI 1422
|
....*..
gi 446516975 211 E-GGKIV 216
Cdd:PTZ00265 1423 KrSDKIV 1429
|
|
| nikD |
PRK10418 |
nickel transporter ATP-binding protein NikD; Provisional |
18-216 |
4.96e-14 |
|
nickel transporter ATP-binding protein NikD; Provisional
Pssm-ID: 236688 [Multi-domain] Cd Length: 254 Bit Score: 68.96 E-value: 4.96e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 18 IAGLTVNIKQGEFVYVVGPSGAGKS----TFIKMMYREEKPSTGSINVNGLTIETLAERDvpyfrRQLGVIFQD----FK 89
Cdd:PRK10418 19 VHGVSLTLQRGRVLALVGGSGSGKSltcaAALGILPAGVRQTAGRVLLDGKPVAPCALRG-----RKIATIMQNprsaFN 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 90 llPKLTVYENVSFALEVIEEEPDaiRERVTEVLGLVGLEDRADAL---PSELSGGEQQRVAIARAIVNRPKVVIADEPTG 166
Cdd:PRK10418 94 --PLHTMHTHARETCLALGKPAD--DATLTAALEAVGLENAARVLklyPFEMSGGMLQRMMIALALLCEAPFIIADEPTT 169
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 446516975 167 NLDIETALDIMNIFTRI-NERGTTIVMATHNADIVNTIRHRVIAIEGGKIV 216
Cdd:PRK10418 170 DLDVVAQARILDLLESIvQKRALGMLLVTHDMGVVARLADDVAVMSHGRIV 220
|
|
| MRP_assoc_pro |
TIGR00957 |
multi drug resistance-associated protein (MRP); This model describes multi drug ... |
21-215 |
1.49e-13 |
|
multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]
Pssm-ID: 188098 [Multi-domain] Cd Length: 1522 Bit Score: 69.20 E-value: 1.49e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 21 LTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLAERDVpyfRRQLGVIFQDfKLLPKLTVYENV 100
Cdd:TIGR00957 1305 INVTIHGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDGLNIAKIGLHDL---RFKITIIPQD-PVLFSGSLRMNL 1380
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 101 SFALEVIEEEpdairerVTEVLGLVGLEDRADALPSE-----------LSGGEQQRVAIARAIVNRPKVVIADEPTGNLD 169
Cdd:TIGR00957 1381 DPFSQYSDEE-------VWWALELAHLKTFVSALPDKldhecaeggenLSVGQRQLVCLARALLRKTKILVLDEATAAVD 1453
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 446516975 170 IETAlDIMNIFTRINERGTTIVMATHNadiVNTIRH--RVIAIEGGKI 215
Cdd:TIGR00957 1454 LETD-NLIQSTIRTQFEDCTVLTIAHR---LNTIMDytRVIVLDKGEV 1497
|
|
| PLN03130 |
PLN03130 |
ABC transporter C family member; Provisional |
2-216 |
1.67e-13 |
|
ABC transporter C family member; Provisional
Pssm-ID: 215595 [Multi-domain] Cd Length: 1622 Bit Score: 69.38 E-value: 1.67e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 2 IKMTNVYKEY-PNGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLAERDVpyfRRQ 80
Cdd:PLN03130 1238 IKFEDVVLRYrPELPPVLHGLSFEISPSEKVGIVGRTGAGKSSMLNALFRIVELERGRILIDGCDISKFGLMDL---RKV 1314
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 81 LGVIFQDFKLLPKltvyeNVSFALEVIEEEPDAireRVTEVLGLVGLEDRA-------DALPSE----LSGGEQQRVAIA 149
Cdd:PLN03130 1315 LGIIPQAPVLFSG-----TVRFNLDPFNEHNDA---DLWESLERAHLKDVIrrnslglDAEVSEagenFSVGQRQLLSLA 1386
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446516975 150 RAIVNRPKVVIADEPTGNLDIET-ALdimnIFTRINE--RGTTIVMATHNadiVNTI--RHRVIAIEGGKIV 216
Cdd:PLN03130 1387 RALLRRSKILVLDEATAAVDVRTdAL----IQKTIREefKSCTMLIIAHR---LNTIidCDRILVLDAGRVV 1451
|
|
| ABC_FeS_Assembly |
cd03217 |
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of ... |
20-224 |
2.10e-13 |
|
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of iron-sulfur clusters (Fe-S) depends on multi-protein systems. The SUF system of E. coli and Erwinia chrysanthemi is important for Fe-S biogenesis under stressful conditions. The SUF system is made of six proteins: SufC is an atypical cytoplasmic ABC-ATPase, which forms a complex with SufB and SufD; SufA plays the role of a scaffold protein for assembly of iron-sulfur clusters and delivery to target proteins; SufS is a cysteine desulfurase which mobilizes the sulfur atom from cysteine and provides it to the cluster; SufE has no associated function yet.
Pssm-ID: 213184 [Multi-domain] Cd Length: 200 Bit Score: 66.40 E-value: 2.10e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 20 GLTVNIKQGEFVYVVGPSGAGKSTFIK--MMYREEKPSTGSINVNGLTIETLA--ERdvpyFRRQLGVIFQDFKLLPKLT 95
Cdd:cd03217 18 GVNLTIKKGEVHALMGPNGSGKSTLAKtiMGHPKYEVTEGEILFKGEDITDLPpeER----ARLGIFLAFQYPPEIPGVK 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 96 V-----YENVSFalevieeepdairervtevlglvgledradalpselSGGEQQRVAIARAIVNRPKVVIADEPTGNLDI 170
Cdd:cd03217 94 NadflrYVNEGF------------------------------------SGGEKKRNEILQLLLLEPDLAILDEPDSGLDI 137
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446516975 171 ETALDIMNIFTRINERGTTIVMATHNADIVNTIR--------HRVIAIEGGKIVRDEIE-GGY 224
Cdd:cd03217 138 DALRLVAEVINKLREEGKSVLIITHYQRLLDYIKpdrvhvlyDGRIVKSGDKELALEIEkKGY 200
|
|
| PRK11147 |
PRK11147 |
ABC transporter ATPase component; Reviewed |
22-172 |
2.87e-13 |
|
ABC transporter ATPase component; Reviewed
Pssm-ID: 236861 [Multi-domain] Cd Length: 635 Bit Score: 68.44 E-value: 2.87e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 22 TVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVnGLTIEtlaerdVPYF---RRQLGvifqdfkllPKLTVYE 98
Cdd:PRK11147 339 SAQVQRGDKIALIGPNGCGKTTLLKLMLGQLQADSGRIHC-GTKLE------VAYFdqhRAELD---------PEKTVMD 402
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 99 NVSFALEVIEeepdaIRERVTEVLGLvgLED------RADALPSELSGGEQQRVAIARAIVNRPKVVIADEPTGNLDIET 172
Cdd:PRK11147 403 NLAEGKQEVM-----VNGRPRHVLGY--LQDflfhpkRAMTPVKALSGGERNRLLLARLFLKPSNLLILDEPTNDLDVET 475
|
|
| PRK15439 |
PRK15439 |
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional |
21-215 |
3.64e-13 |
|
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
Pssm-ID: 185336 [Multi-domain] Cd Length: 510 Bit Score: 67.77 E-value: 3.64e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 21 LTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLAERD--------VPYFRRQLGvIFQDFKL-- 90
Cdd:PRK15439 282 ISLEVRAGEILGLAGVVGAGRTELAETLYGLRPARGGRIMLNGKEINALSTAQrlarglvyLPEDRQSSG-LYLDAPLaw 360
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 91 -LPKLTvYENVSFALEVIEEEpdAIRERVTEVLGlVGLEDrADALPSELSGGEQQRVAIARAIVNRPKVVIADEPTGNLD 169
Cdd:PRK15439 361 nVCALT-HNRRGFWIKPAREN--AVLERYRRALN-IKFNH-AEQAARTLSGGNQQKVLIAKCLEASPQLLIVDEPTRGVD 435
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 446516975 170 IETALDIMNIFTRINERGTTIVMATHNADIVNTIRHRVIAIEGGKI 215
Cdd:PRK15439 436 VSARNDIYQLIRSIAAQNVAVLFISSDLEEIEQMADRVLVMHQGEI 481
|
|
| 3a01205 |
TIGR00956 |
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other] |
25-195 |
4.71e-13 |
|
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273362 [Multi-domain] Cd Length: 1394 Bit Score: 67.83 E-value: 4.71e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 25 IKQGEFVYVVGPSGAGKSTFIKMMyrEEKPSTGSIN-----VNGLTIETlaerdvpYFRRQLGVIFQDFKLLPKLTVYEN 99
Cdd:TIGR00956 786 VKPGTLTALMGASGAGKTTLLNVL--AERVTTGVITggdrlVNGRPLDS-------SFQRSIGYVQQQDLHLPTSTVRES 856
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 100 VSFAL------EVIEEEPDairERVTEVLGLVGLEDRADAL---PSE-LSGGEQQRVAIARAIVNRPKVVI-ADEPTGNL 168
Cdd:TIGR00956 857 LRFSAylrqpkSVSKSEKM---EYVEEVIKLLEMESYADAVvgvPGEgLNVEQRKRLTIGVELVAKPKLLLfLDEPTSGL 933
|
170 180
....*....|....*....|....*..
gi 446516975 169 DIETALDIMNIFTRINERGTTIVMATH 195
Cdd:TIGR00956 934 DSQTAWSICKLMRKLADHGQAILCTIH 960
|
|
| PLN03232 |
PLN03232 |
ABC transporter C family member; Provisional |
1-216 |
9.57e-13 |
|
ABC transporter C family member; Provisional
Pssm-ID: 215640 [Multi-domain] Cd Length: 1495 Bit Score: 66.92 E-value: 9.57e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 1 MIKMTNVYKEYPNGMKAIA-GLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLAERDVpyfRR 79
Cdd:PLN03232 1234 SIKFEDVHLRYRPGLPPVLhGLSFFVSPSEKVGVVGRTGAGKSSMLNALFRIVELEKGRIMIDDCDVAKFGLTDL---RR 1310
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 80 QLGVIFQDFKLLPKltvyeNVSFALEVIEEEPDAIRERVTEVLGLVGLEDRA----DALPSE----LSGGEQQRVAIARA 151
Cdd:PLN03232 1311 VLSIIPQSPVLFSG-----TVRFNIDPFSEHNDADLWEALERAHIKDVIDRNpfglDAEVSEggenFSVGQRQLLSLARA 1385
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446516975 152 IVNRPKVVIADEPTGNLDIETALDIMNIFtRINERGTTIVMATHNadiVNTIR--HRVIAIEGGKIV 216
Cdd:PLN03232 1386 LLRRSKILVLDEATASVDVRTDSLIQRTI-REEFKSCTMLVIAHR---LNTIIdcDKILVLSSGQVL 1448
|
|
| PRK11819 |
PRK11819 |
putative ABC transporter ATP-binding protein; Reviewed |
18-172 |
1.72e-12 |
|
putative ABC transporter ATP-binding protein; Reviewed
Pssm-ID: 236992 [Multi-domain] Cd Length: 556 Bit Score: 65.91 E-value: 1.72e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 18 IAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVnGLTIEtLA----ERDvpyfrrqlgvifqdfKLLPK 93
Cdd:PRK11819 340 IDDLSFSLPPGGIVGIIGPNGAGKSTLFKMITGQEQPDSGTIKI-GETVK-LAyvdqSRD---------------ALDPN 402
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 94 LTVYENVSFALEVIEeepdairervtevLGLVGLEDRA------------DALPSELSGGEQQRVAIARAIVNRPKVVIA 161
Cdd:PRK11819 403 KTVWEEISGGLDIIK-------------VGNREIPSRAyvgrfnfkggdqQKKVGVLSGGERNRLHLAKTLKQGGNVLLL 469
|
170
....*....|.
gi 446516975 162 DEPTGNLDIET 172
Cdd:PRK11819 470 DEPTNDLDVET 480
|
|
| ABC_RNaseL_inhibitor_domain1 |
cd03236 |
The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ... |
12-196 |
2.48e-12 |
|
The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI s are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLIs have an N-terminal Fe-S domain and two nucleotide binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.
Pssm-ID: 213203 [Multi-domain] Cd Length: 255 Bit Score: 64.31 E-value: 2.48e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 12 PNGMKaIAGLTVnIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLAE-RDVP---YFRR----QLGV 83
Cdd:cd03236 12 PNSFK-LHRLPV-PREGQVLGLVGPNGIGKSTALKILAGKLKPNLGKFDDPPDWDEILDEfRGSElqnYFTKllegDVKV 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 84 IF--QDFKLLPKlTVYENVSFALEVIEEEpdAIRERVTEVLGLVGLEDRAdalPSELSGGEQQRVAIARAIVNRPKVVIA 161
Cdd:cd03236 90 IVkpQYVDLIPK-AVKGKVGELLKKKDER--GKLDELVDQLELRHVLDRN---IDQLSGGELQRVAIAAALARDADFYFF 163
|
170 180 190
....*....|....*....|....*....|....*
gi 446516975 162 DEPTGNLDIETALDIMNIFTRINERGTTIVMATHN 196
Cdd:cd03236 164 DEPSSYLDIKQRLNAARLIRELAEDDNYVLVVEHD 198
|
|
| NupO |
COG3845 |
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ... |
12-216 |
2.88e-12 |
|
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];
Pssm-ID: 443055 [Multi-domain] Cd Length: 504 Bit Score: 65.05 E-value: 2.88e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 12 PNGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLAERDvpyfRRQLGVIF-----Q 86
Cdd:COG3845 268 DRGVPALKDVSLEVRAGEILGIAGVAGNGQSELAEALAGLRPPASGSIRLDGEDITGLSPRE----RRRLGVAYipedrL 343
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 87 DFKLLPKLTVYENvsFALEVIEEEP---------DAIRERVTEVLG-----LVGLEDRADALpselSGGEQQRVAIARAI 152
Cdd:COG3845 344 GRGLVPDMSVAEN--LILGRYRRPPfsrggfldrKAIRAFAEELIEefdvrTPGPDTPARSL----SGGNQQKVILAREL 417
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446516975 153 VNRPKVVIADEPTGNLDIETALDIMNIFTRINERGTTIVMATHNADIVNTIRHRVIAIEGGKIV 216
Cdd:COG3845 418 SRDPKLLIAAQPTRGLDVGAIEFIHQRLLELRDAGAAVLLISEDLDEILALSDRIAVMYEGRIV 481
|
|
| GguA |
NF040905 |
sugar ABC transporter ATP-binding protein; |
4-204 |
3.92e-12 |
|
sugar ABC transporter ATP-binding protein;
Pssm-ID: 468840 [Multi-domain] Cd Length: 500 Bit Score: 64.81 E-value: 3.92e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 4 MTNVYKEYPnGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMM--------YreekpsTGSINVNGLTIETLAERDvp 75
Cdd:NF040905 4 MRGITKTFP-GVKALDDVNLSVREGEIHALCGENGAGKSTLMKVLsgvyphgsY------EGEILFDGEVCRFKDIRD-- 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 76 yfRRQLGV--IFQDFKLLPKLTVYENVSFALE-----VIEEepDAIRERVTEVLGLVGLEDRADALPSELSGGEQQRVAI 148
Cdd:NF040905 75 --SEALGIviIHQELALIPYLSIAENIFLGNErakrgVIDW--NETNRRARELLAKVGLDESPDTLVTDIGVGKQQLVEI 150
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446516975 149 ARAIVNRPKVVIADEPTGNL---DIETALDIMNIFTrinERGTTIVMATHN-------ADIVNTIR 204
Cdd:NF040905 151 AKALSKDVKLLILDEPTAALneeDSAALLDLLLELK---AQGITSIIISHKlneirrvADSITVLR 213
|
|
| PRK11819 |
PRK11819 |
putative ABC transporter ATP-binding protein; Reviewed |
4-172 |
8.76e-12 |
|
putative ABC transporter ATP-binding protein; Reviewed
Pssm-ID: 236992 [Multi-domain] Cd Length: 556 Bit Score: 63.98 E-value: 8.76e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 4 MTNVYKEYPNGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINV-NGLTIetlaerdvpyfrrqlG 82
Cdd:PRK11819 9 MNRVSKVVPPKKQILKDISLSFFPGAKIGVLGLNGAGKSTLLRIMAGVDKEFEGEARPaPGIKV---------------G 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 83 VIFQDFKLLPKLTVYENVSFAL-----------EVIEE--EPDA-----IRE--RVTEVLGLVG-------LEDRADAL- 134
Cdd:PRK11819 74 YLPQEPQLDPEKTVRENVEEGVaevkaaldrfnEIYAAyaEPDAdfdalAAEqgELQEIIDAADawdldsqLEIAMDALr 153
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 446516975 135 -P------SELSGGEQQRVAIARAIVNRPKVVIADEPTGNLDIET 172
Cdd:PRK11819 154 cPpwdakvTKLSGGERRRVALCRLLLEKPDMLLLDEPTNHLDAES 198
|
|
| rim_protein |
TIGR01257 |
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ... |
1-198 |
9.83e-12 |
|
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]
Pssm-ID: 130324 [Multi-domain] Cd Length: 2272 Bit Score: 63.88 E-value: 9.83e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 1 MIKMTNVYKEYP-NGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETlaerDVPYFRR 79
Cdd:TIGR01257 1937 ILRLNELTKVYSgTSSPAVDRLCVGVRPGECFGLLGVNGAGKTTTFKMLTGDTTVTSGDATVAGKSILT----NISDVHQ 2012
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 80 QLGVIFQdFKLLPKLTVYENVSFALEVIEEEPDAIRERVTE-VLGLVGLEDRADALPSELSGGEQQRVAIARAIVNRPKV 158
Cdd:TIGR01257 2013 NMGYCPQ-FDAIDDLLTGREHLYLYARLRGVPAEEIEKVANwSIQSLGLSLYADRLAGTYSGGNKRKLSTAIALIGCPPL 2091
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 446516975 159 VIADEPTGNLDIETALDIMNIFTRINERGTTIVMATHNAD 198
Cdd:TIGR01257 2092 VLLDEPTTGMDPQARRMLWNTIVSIIREGRAVVLTSHSME 2131
|
|
| PTZ00243 |
PTZ00243 |
ABC transporter; Provisional |
20-207 |
1.35e-11 |
|
ABC transporter; Provisional
Pssm-ID: 240327 [Multi-domain] Cd Length: 1560 Bit Score: 63.64 E-value: 1.35e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 20 GLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLAERDVpyfRRQLGVIFQDfkllPKL---TV 96
Cdd:PTZ00243 1328 GVSFRIAPREKVGIVGRTGSGKSTLLLTFMRMVEVCGGEIRVNGREIGAYGLREL---RRQFSMIPQD----PVLfdgTV 1400
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 97 YENVSFALEVIEEEPDA------IRERVTEVLGlvGLEDRADALPSELSGGEQQRVAIARAIVNRPKVVI-ADEPTGNLD 169
Cdd:PTZ00243 1401 RQNVDPFLEASSAEVWAalelvgLRERVASESE--GIDSRVLEGGSNYSVGQRQLMCMARALLKKGSGFIlMDEATANID 1478
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 446516975 170 ieTALD--IMNiftrinergttIVMATHNADIVNTIRHRV 207
Cdd:PTZ00243 1479 --PALDrqIQA-----------TVMSAFSAYTVITIAHRL 1505
|
|
| ycf16 |
CHL00131 |
sulfate ABC transporter protein; Validated |
13-227 |
1.43e-11 |
|
sulfate ABC transporter protein; Validated
Pssm-ID: 214372 [Multi-domain] Cd Length: 252 Bit Score: 61.97 E-value: 1.43e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 13 NGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMM--YREEKPSTGSINVNGLTIETLAerdvPYFRRQLGVI--FQ-- 86
Cdd:CHL00131 18 NENEILKGLNLSINKGEIHAIMGPNGSGKSTLSKVIagHPAYKILEGDILFKGESILDLE----PEERAHLGIFlaFQyp 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 87 ---------DFKLLpkltVYENVSFALEVIEEEPDAIRERVTEVLGLVGLEdradalPSEL--------SGGEQQRVAIA 149
Cdd:CHL00131 94 ieipgvsnaDFLRL----AYNSKRKFQGLPELDPLEFLEIINEKLKLVGMD------PSFLsrnvnegfSGGEKKRNEIL 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 150 RAIVNRPKVVIADEPTGNLDIETALDIMNIFTRINERGTTIVMATH--------NADIVNTIRHRVIAIEGGKIVRDEIE 221
Cdd:CHL00131 164 QMALLDSELAILDETDSGLDIDALKIIAEGINKLMTSENSIILITHyqrlldyiKPDYVHVMQNGKIIKTGDAELAKELE 243
|
....*.
gi 446516975 222 gGYGYE 227
Cdd:CHL00131 244 -KKGYD 248
|
|
| PRK10938 |
PRK10938 |
putative molybdenum transport ATP-binding protein ModF; Provisional |
2-217 |
2.12e-11 |
|
putative molybdenum transport ATP-binding protein ModF; Provisional
Pssm-ID: 182852 [Multi-domain] Cd Length: 490 Bit Score: 62.72 E-value: 2.12e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 2 IKMTNVYKEYpNGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMyREEKPSTGSinvNGLTI--------ETLAE-- 71
Cdd:PRK10938 261 IVLNNGVVSY-NDRPILHNLSWQVNPGEHWQIVGPNGAGKSTLLSLI-TGDHPQGYS---NDLTLfgrrrgsgETIWDik 335
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 72 RDVPYFRRQL-----------GVIFQDFklLPKLTVYENVSfalevieeepDAIRERVTEVLGLVGLEDR-ADALPSELS 139
Cdd:PRK10938 336 KHIGYVSSSLhldyrvstsvrNVILSGF--FDSIGIYQAVS----------DRQQKLAQQWLDILGIDKRtADAPFHSLS 403
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 140 GGEQQRVAIARAIVNRPKVVIADEPTGNLD------IETALDIMniftrINERGTTIVMATHNA-DIVNTIRHRVIAIEG 212
Cdd:PRK10938 404 WGQQRLALIVRALVKHPTLLILDEPLQGLDplnrqlVRRFVDVL-----ISEGETQLLFVSHHAeDAPACITHRLEFVPD 478
|
....*
gi 446516975 213 GKIVR 217
Cdd:PRK10938 479 GDIYR 483
|
|
| PRK13540 |
PRK13540 |
cytochrome c biogenesis protein CcmA; Provisional |
21-195 |
2.32e-11 |
|
cytochrome c biogenesis protein CcmA; Provisional
Pssm-ID: 184127 [Multi-domain] Cd Length: 200 Bit Score: 60.73 E-value: 2.32e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 21 LTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIetlaERDVPYFRRQLGVIFQDFKLLPKLTVYENV 100
Cdd:PRK13540 20 ISFHLPAGGLLHLKGSNGAGKTTLLKLIAGLLNPEKGEILFERQSI----KKDLCTYQKQLCFVGHRSGINPYLTLRENC 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 101 SFALEVieeepDAIRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIVNRPKVVIADEPTGNLDietALDIMNIF 180
Cdd:PRK13540 96 LYDIHF-----SPGAVGITELCRLFSLEHLIDYPCGLLSSGQKRQVALLRLWMSKAKLWLLDEPLVALD---ELSLLTII 167
|
170
....*....|....*...
gi 446516975 181 TRINE---RGTTIVMATH 195
Cdd:PRK13540 168 TKIQEhraKGGAVLLTSH 185
|
|
| PRK10789 |
PRK10789 |
SmdA family multidrug ABC transporter permease/ATP-binding protein; |
11-193 |
2.70e-11 |
|
SmdA family multidrug ABC transporter permease/ATP-binding protein;
Pssm-ID: 182732 [Multi-domain] Cd Length: 569 Bit Score: 62.42 E-value: 2.70e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 11 YPNGMK-AIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLAERDvpyFRRQLGVIFQdfk 89
Cdd:PRK10789 323 YPQTDHpALENVNFTLKPGQMLGICGPTGSGKSTLLSLIQRHFDVSEGDIRFHDIPLTKLQLDS---WRSRLAVVSQ--- 396
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 90 lLPKL---TVYENVSFAlevieeEPDAIRERVTEVLGLVGLEDRADALPS-----------ELSGGEQQRVAIARAIVNR 155
Cdd:PRK10789 397 -TPFLfsdTVANNIALG------RPDATQQEIEHVARLASVHDDILRLPQgydtevgergvMLSGGQKQRISIARALLLN 469
|
170 180 190
....*....|....*....|....*....|....*...
gi 446516975 156 PKVVIADEPTGNLDIETALDIMNIFTRINERGTTIVMA 193
Cdd:PRK10789 470 AEILILDDALSAVDGRTEHQILHNLRQWGEGRTVIISA 507
|
|
| ABCC_SUR2 |
cd03288 |
ATP-binding cassette domain 2 of the sulfonylurea receptor SUR; The SUR domain 2. The ... |
2-216 |
4.59e-11 |
|
ATP-binding cassette domain 2 of the sulfonylurea receptor SUR; The SUR domain 2. The sulfonylurea receptor SUR is an ATP binding cassette (ABC) protein of the ABCC/MRP family. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.
Pssm-ID: 213255 [Multi-domain] Cd Length: 257 Bit Score: 60.69 E-value: 4.59e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 2 IKMTNVYKEYPNGMKAI-AGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLAerdVPYFRRQ 80
Cdd:cd03288 20 IKIHDLCVRYENNLKPVlKHVKAYIKPGQKVGICGRTGSGKSSLSLAFFRMVDIFDGKIVIDGIDISKLP---LHTLRSR 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 81 LGVIFQDFKLLPKltvyeNVSFALEvieEEPDAIRERVTEVLGLVGLEDRADALPSEL-----------SGGEQQRVAIA 149
Cdd:cd03288 97 LSIILQDPILFSG-----SIRFNLD---PECKCTDDRLWEALEIAQLKNMVKSLPGGLdavvteggenfSVGQRQLFCLA 168
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446516975 150 RAIVNRPKVVIADEPTGNLDIETAldimNIFTRinergttIVMATHNADIVNTIRHRVIAIEGGKIV 216
Cdd:cd03288 169 RAFVRKSSILIMDEATASIDMATE----NILQK-------VVMTAFADRTVVTIAHRVSTILDADLV 224
|
|
| PTZ00243 |
PTZ00243 |
ABC transporter; Provisional |
21-216 |
5.46e-11 |
|
ABC transporter; Provisional
Pssm-ID: 240327 [Multi-domain] Cd Length: 1560 Bit Score: 61.72 E-value: 5.46e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 21 LTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSInvngltietLAERDVPYFRRQLGVIfqdfkllpKLTVYENV 100
Cdd:PTZ00243 679 VSVSVPRGKLTVVLGATGSGKSTLLQSLLSQFEISEGRV---------WAERSIAYVPQQAWIM--------NATVRGNI 741
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 101 SFaleVIEEEP----DAIR----ERVTEVLGlVGLEDRADALPSELSGGEQQRVAIARAIVNRPKVVIADEPTGNLDIET 172
Cdd:PTZ00243 742 LF---FDEEDAarlaDAVRvsqlEADLAQLG-GGLETEIGEKGVNLSGGQKARVSLARAVYANRDVYLLDDPLSALDAHV 817
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 446516975 173 ALDIMNIFTRINERGTTIVMATHNADIVNTIRHrVIAIEGGKIV 216
Cdd:PTZ00243 818 GERVVEECFLGALAGKTRVLATHQVHVVPRADY-VVALGDGRVE 860
|
|
| PRK13541 |
PRK13541 |
cytochrome c biogenesis protein CcmA; Provisional |
32-217 |
9.51e-11 |
|
cytochrome c biogenesis protein CcmA; Provisional
Pssm-ID: 184128 [Multi-domain] Cd Length: 195 Bit Score: 59.11 E-value: 9.51e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 32 YVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLAERDVPYFRRQLGVifqdfKLlpKLTVYENVSFALEVIEEEp 111
Cdd:PRK13541 30 YIKGANGCGKSSLLRMIAGIMQPSSGNIYYKNCNINNIAKPYCTYIGHNLGL-----KL--EMTVFENLKFWSEIYNSA- 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 112 dairERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIVNRPKVVIADEPTGNLDIETAlDIMNiftrinergTTIV 191
Cdd:PRK13541 102 ----ETLYAAIHYFKLHDLLDEKCYSLSSGMQKIVAIARLIACQSDLWLLDEVETNLSKENR-DLLN---------NLIV 167
|
170 180
....*....|....*....|....*.
gi 446516975 192 MATHNADIVNTIRHRVIAIEGGKIVR 217
Cdd:PRK13541 168 MKANSGGIVLLSSHLESSIKSAQILQ 193
|
|
| xylG |
TIGR02633 |
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ... |
16-220 |
1.11e-10 |
|
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]
Pssm-ID: 131681 [Multi-domain] Cd Length: 500 Bit Score: 60.61 E-value: 1.11e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 16 KAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYRE-EKPSTGSINVNGLTIETLAERD--------VPYFRRQLGVIfq 86
Cdd:TIGR02633 274 KRVDDVSFSLRRGEILGVAGLVGAGRTELVQALFGAyPGKFEGNVFINGKPVDIRNPAQairagiamVPEDRKRHGIV-- 351
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 87 dfkllPKLTVYENVSFA-------LEVIEE--EPDAIRERVTEVlglvGLEDRADALP-SELSGGEQQRVAIARAIVNRP 156
Cdd:TIGR02633 352 -----PILGVGKNITLSvlksfcfKMRIDAaaELQIIGSAIQRL----KVKTASPFLPiGRLSGGNQQKAVLAKMLLTNP 422
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446516975 157 KVVIADEPTGNLDIETALDIMNIFTRINERGTTIVMATHNADIVNTIRHRVIAIEGGKIVRDEI 220
Cdd:TIGR02633 423 RVLILDEPTRGVDVGAKYEIYKLINQLAQEGVAIIVVSSELAEVLGLSDRVLVIGEGKLKGDFV 486
|
|
| 3a01203 |
TIGR00954 |
Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, ... |
1-195 |
2.86e-10 |
|
Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]
Pssm-ID: 273360 [Multi-domain] Cd Length: 659 Bit Score: 59.38 E-value: 2.86e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 1 MIKMTNVYKEYPNGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMY--------REEKPSTGSINVngltietLAER 72
Cdd:TIGR00954 451 GIKFENIPLVTPNGDVLIESLSFEVPSGNNLLICGPNGCGKSSLFRILGelwpvyggRLTKPAKGKLFY-------VPQR 523
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 73 dvPY-----FRRQlgVIFQDFKLLPKLTVYENVSfaLEVIEEEPDaIRERVTEVLGLVGLEDRADalpsELSGGEQQRVA 147
Cdd:TIGR00954 524 --PYmtlgtLRDQ--IIYPDSSEDMKRRGLSDKD--LEQILDNVQ-LTHILEREGGWSAVQDWMD----VLSGGEKQRIA 592
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 446516975 148 IARAIVNRPKVVIADEPTG--NLDIETAldimnIFTRINERGTTIVMATH 195
Cdd:TIGR00954 593 MARLFYHKPQFAILDECTSavSVDVEGY-----MYRLCREFGITLFSVSH 637
|
|
| ABC_RNaseL_inhibitor |
cd03222 |
ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a ... |
25-212 |
2.89e-10 |
|
ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins, and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains, which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.
Pssm-ID: 213189 [Multi-domain] Cd Length: 177 Bit Score: 57.20 E-value: 2.89e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 25 IKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIetlaerdvpyfrrqlgvifqdfkllpkltVYEnvsfal 104
Cdd:cd03222 22 VKEGEVIGIVGPNGTGKTTAVKILAGQLIPNGDNDEWDGITP-----------------------------VYK------ 66
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 105 evieeePDAIrervtevlglvgledradalpsELSGGEQQRVAIARAIVNRPKVVIADEPTGNLDIETALDIMNIFTRIN 184
Cdd:cd03222 67 ------PQYI----------------------DLSGGELQRVAIAAALLRNATFYLFDEPSAYLDIEQRLNAARAIRRLS 118
|
170 180
....*....|....*....|....*....
gi 446516975 185 ERGT-TIVMATHNADIVNTIRHRVIAIEG 212
Cdd:cd03222 119 EEGKkTALVVEHDLAVLDYLSDRIHVFEG 147
|
|
| PLN03232 |
PLN03232 |
ABC transporter C family member; Provisional |
18-212 |
3.34e-10 |
|
ABC transporter C family member; Provisional
Pssm-ID: 215640 [Multi-domain] Cd Length: 1495 Bit Score: 59.60 E-value: 3.34e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 18 IAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPS-TGSINVNGltieTLAErdVPyfrrQLGVIFQdfkllpkLTV 96
Cdd:PLN03232 633 LSDINLEIPVGSLVAIVGGTGEGKTSLISAMLGELSHAeTSSVVIRG----SVAY--VP----QVSWIFN-------ATV 695
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 97 YENVSFALEVieeEPdairERVTEVLGLVGLEDRADALPSE-----------LSGGEQQRVAIARAIVNRPKVVIADEPT 165
Cdd:PLN03232 696 RENILFGSDF---ES----ERYWRAIDVTALQHDLDLLPGRdlteigergvnISGGQKQRVSMARAVYSNSDIYIFDDPL 768
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 446516975 166 GNLDIETALDIMNIFTRINERGTTIVMATHNADIVNTIRHRVIAIEG 212
Cdd:PLN03232 769 SALDAHVAHQVFDSCMKDELKGKTRVLVTNQLHFLPLMDRIILVSEG 815
|
|
| araG |
PRK11288 |
L-arabinose ABC transporter ATP-binding protein AraG; |
14-216 |
3.78e-10 |
|
L-arabinose ABC transporter ATP-binding protein AraG;
Pssm-ID: 183077 [Multi-domain] Cd Length: 501 Bit Score: 58.77 E-value: 3.78e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 14 GMKAIAGLTVniKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLAERDV--------PYFRRQLGVIf 85
Cdd:PRK11288 267 GLREPISFSV--RAGEIVGLFGLVGAGRSELMKLLYGATRRTAGQVYLDGKPIDIRSPRDAiragimlcPEDRKAEGII- 343
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 86 qdfkllPKLTVYENV--------SFALEVIeeepDAIRERVTEVLGLVGLEDR---ADALPSELSGGEQQRVAIARAIVN 154
Cdd:PRK11288 344 ------PVHSVADNInisarrhhLRAGCLI----NNRWEAENADRFIRSLNIKtpsREQLIMNLSGGNQQKAILGRWLSE 413
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446516975 155 RPKVVIADEPTGNLDIETALDIMNIFTRINERGTTIVMATHNADIVNTIRHRVIAIEGGKIV 216
Cdd:PRK11288 414 DMKVILLDEPTRGIDVGAKHEIYNVIYELAAQGVAVLFVSSDLPEVLGVADRIVVMREGRIA 475
|
|
| 40850658_otr |
NF000106 |
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit; |
15-218 |
6.35e-10 |
|
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;
Pssm-ID: 411078 [Multi-domain] Cd Length: 351 Bit Score: 58.21 E-value: 6.35e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 15 MKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMY--------REEKPSTGSINVNGLTIETLAERDVPYFRRQlgvifq 86
Cdd:NF000106 26 VKAVDGVDLDVREGTVLGVLGP*GAA**RGALPAHv*gpdagrRPWRF*TWCANRRALRRTIG*HRPVR*GRRE------ 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 87 dfkllpKLTVYENVSFALEVIEEEPDAIRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIVNRPKVVIADEPTG 166
Cdd:NF000106 100 ------SFSGRENLYMIGR*LDLSRKDARARADELLERFSLTEAAGRAAAKYSGGMRRRLDLAASMIGRPAVLYLDEPTT 173
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 446516975 167 NLDIETALDIMNIFTRINERGTTIVMATHNADIVNTIRHRVIAIEGGKIVRD 218
Cdd:NF000106 174 GLDPRTRNEVWDEVRSMVRDGATVLLTTQYMEEAEQLAHELTVIDRGRVIAD 225
|
|
| PRK09700 |
PRK09700 |
D-allose ABC transporter ATP-binding protein AlsA; |
16-215 |
1.29e-09 |
|
D-allose ABC transporter ATP-binding protein AlsA;
Pssm-ID: 182036 [Multi-domain] Cd Length: 510 Bit Score: 57.49 E-value: 1.29e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 16 KAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLAERD--------VPYFRRQLGV---- 83
Cdd:PRK09700 277 KKVRDISFSVCRGEILGFAGLVGSGRTELMNCLFGVDKRAGGEIRLNGKDISPRSPLDavkkgmayITESRRDNGFfpnf 356
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 84 -IFQDFKLLP--KLTVYENVSFALEVIEEEPDAIRERVTEVLGLVGLEDRAdalpSELSGGEQQRVAIARAIVNRPKVVI 160
Cdd:PRK09700 357 sIAQNMAISRslKDGGYKGAMGLFHEVDEQRTAENQRELLALKCHSVNQNI----TELSGGNQQKVLISKWLCCCPEVII 432
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 446516975 161 ADEPTGNLDIETALDIMNIFTRINERGTTIVMATHNADIVNTIRHRVIAIEGGKI 215
Cdd:PRK09700 433 FDEPTRGIDVGAKAEIYKVMRQLADDGKVILMVSSELPEIITVCDRIAVFCEGRL 487
|
|
| PRK13409 |
PRK13409 |
ribosome biogenesis/translation initiation ATPase RLI; |
12-170 |
1.64e-09 |
|
ribosome biogenesis/translation initiation ATPase RLI;
Pssm-ID: 184037 [Multi-domain] Cd Length: 590 Bit Score: 57.13 E-value: 1.64e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 12 PNGMKaIAGLTVnIKQGEFVYVVGPSGAGKSTFIKMMYREEKPstgsiNVNGLTIETLAERDVPYFRR-QLGVIFQDFK- 89
Cdd:PRK13409 85 VNGFK-LYGLPI-PKEGKVTGILGPNGIGKTTAVKILSGELIP-----NLGDYEEEPSWDEVLKRFRGtELQNYFKKLYn 157
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 90 -------------LLPKLtVYENVSFALEVIEEepdaiRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIVNRP 156
Cdd:PRK13409 158 geikvvhkpqyvdLIPKV-FKGKVRELLKKVDE-----RGKLDEVVERLGLENILDRDISELSGGELQRVAIAAALLRDA 231
|
170
....*....|....
gi 446516975 157 KVVIADEPTGNLDI 170
Cdd:PRK13409 232 DFYFFDEPTSYLDI 245
|
|
| PLN03130 |
PLN03130 |
ABC transporter C family member; Provisional |
23-215 |
1.87e-09 |
|
ABC transporter C family member; Provisional
Pssm-ID: 215595 [Multi-domain] Cd Length: 1622 Bit Score: 57.06 E-value: 1.87e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 23 VNIKQGEFVYVVGPSGAGKSTFIKMMYREEKP-STGSINVNGltieTLAErdVPyfrrQLGVIFQdfkllpkLTVYENVS 101
Cdd:PLN03130 638 LDVPVGSLVAIVGSTGEGKTSLISAMLGELPPrSDASVVIRG----TVAY--VP----QVSWIFN-------ATVRDNIL 700
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 102 FALEVieeepDAIR-ERVTEVlglVGLEDRADALPS-----------ELSGGEQQRVAIARAIVNRPKVVIADEPTGNLD 169
Cdd:PLN03130 701 FGSPF-----DPERyERAIDV---TALQHDLDLLPGgdlteigergvNISGGQKQRVSMARAVYSNSDVYIFDDPLSALD 772
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 446516975 170 IETALDIMNIFTRINERGTTIVMATHNADIVNTIrHRVIAIEGGKI 215
Cdd:PLN03130 773 AHVGRQVFDKCIKDELRGKTRVLVTNQLHFLSQV-DRIILVHEGMI 817
|
|
| Rli1 |
COG1245 |
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ... |
26-170 |
2.44e-09 |
|
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];
Pssm-ID: 440858 [Multi-domain] Cd Length: 592 Bit Score: 56.72 E-value: 2.44e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 26 KQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINvNGLTIETLAERdvpyFRrqlGVIFQD-FK--------------- 89
Cdd:COG1245 97 KKGKVTGILGPNGIGKSTALKILSGELKPNLGDYD-EEPSWDEVLKR----FR---GTELQDyFKklangeikvahkpqy 168
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 90 --LLPKLtVYENVSFALEVIEEepdaiRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIVNRPKVVIADEPTGN 167
Cdd:COG1245 169 vdLIPKV-FKGTVRELLEKVDE-----RGKLDELAEKLGLENILDRDISELSGGELQRVAIAAALLRDADFYFFDEPSSY 242
|
...
gi 446516975 168 LDI 170
Cdd:COG1245 243 LDI 245
|
|
| PRK10522 |
PRK10522 |
multidrug transporter membrane component/ATP-binding component; Provisional |
2-163 |
2.57e-09 |
|
multidrug transporter membrane component/ATP-binding component; Provisional
Pssm-ID: 236707 [Multi-domain] Cd Length: 547 Bit Score: 56.52 E-value: 2.57e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 2 IKMTNVYKEYPNGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNG--LTIETLAErdvpyFRR 79
Cdd:PRK10522 323 LELRNVTFAYQDNGFSVGPINLTIKRGELLFLIGGNGSGKSTLAMLLTGLYQPQSGEILLDGkpVTAEQPED-----YRK 397
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 80 QLGVIFQDFKLLPKLTVYENvsfaleviEEEPDAIRERVTEVLGL---VGLEDrADALPSELSGGEQQRVAIARAIVNRP 156
Cdd:PRK10522 398 LFSAVFTDFHLFDQLLGPEG--------KPANPALVEKWLERLKMahkLELED-GRISNLKLSKGQKKRLALLLALAEER 468
|
....*..
gi 446516975 157 KVVIADE 163
Cdd:PRK10522 469 DILLLDE 475
|
|
| PRK10982 |
PRK10982 |
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional |
4-198 |
2.59e-09 |
|
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
Pssm-ID: 182880 [Multi-domain] Cd Length: 491 Bit Score: 56.66 E-value: 2.59e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 4 MTNVYKEYPnGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLAERDVpyFRRQLGV 83
Cdd:PRK10982 1 MSNISKSFP-GVKALDNVNLKVRPHSIHALMGENGAGKSTLLKCLFGIYQKDSGSILFQGKEIDFKSSKEA--LENGISM 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 84 IFQDFKLLPKLTVYENV---SFALEVIEEEPDAIRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIVNRPKVVI 160
Cdd:PRK10982 78 VHQELNLVLQRSVMDNMwlgRYPTKGMFVDQDKMYRDTKAIFDELDIDIDPRAKVATLSVSQMQMIEIAKAFSYNAKIVI 157
|
170 180 190
....*....|....*....|....*....|....*...
gi 446516975 161 ADEPTGNLDIETALDIMNIFTRINERGTTIVMATHNAD 198
Cdd:PRK10982 158 MDEPTSSLTEKEVNHLFTIIRKLKERGCGIVYISHKME 195
|
|
| PLN03140 |
PLN03140 |
ABC transporter G family member; Provisional |
6-199 |
4.95e-09 |
|
ABC transporter G family member; Provisional
Pssm-ID: 215599 [Multi-domain] Cd Length: 1470 Bit Score: 56.01 E-value: 4.95e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 6 NVYKEYPNGMKA----------IAGLTVNIKQGEFVYVVGPSGAGKSTFIKMM-------YREekpstGSINVNGLTI-- 66
Cdd:PLN03140 874 NYFVDMPAEMKEqgvtedrlqlLREVTGAFRPGVLTALMGVSGAGKTTLMDVLagrktggYIE-----GDIRISGFPKkq 948
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 67 ETlaerdvpyFRRQLGVIFQDFKLLPKLTVYENVSFAL------EVIEEEPDAIRERVTEVLGLVGLEDRADALP--SEL 138
Cdd:PLN03140 949 ET--------FARISGYCEQNDIHSPQVTVRESLIYSAflrlpkEVSKEEKMMFVDEVMELVELDNLKDAIVGLPgvTGL 1020
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446516975 139 SGGEQQRVAIARAIVNRPKVVIADEPTGNLDIETALDIMNIFTRINERGTTIVMATHNADI 199
Cdd:PLN03140 1021 STEQRKRLTIAVELVANPSIIFMDEPTSGLDARAAAIVMRTVRNTVDTGRTVVCTIHQPSI 1081
|
|
| MRP_assoc_pro |
TIGR00957 |
multi drug resistance-associated protein (MRP); This model describes multi drug ... |
20-215 |
6.02e-09 |
|
multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]
Pssm-ID: 188098 [Multi-domain] Cd Length: 1522 Bit Score: 55.72 E-value: 6.02e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 20 GLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGltietlaerDVPYFRRQlgvifqdfKLLPKLTVYEN 99
Cdd:TIGR00957 656 GITFSIPEGALVAVVGQVGCGKSSLLSALLAEMDKVEGHVHMKG---------SVAYVPQQ--------AWIQNDSLREN 718
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 100 VSFALEVieEEPdaireRVTEVLGLVGLEDRADALPS-----------ELSGGEQQRVAIARAIVNRPKVVIADEPTGNL 168
Cdd:TIGR00957 719 ILFGKAL--NEK-----YYQQVLEACALLPDLEILPSgdrteigekgvNLSGGQKQRVSLARAVYSNADIYLFDDPLSAV 791
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 446516975 169 DIETAldiMNIFTRINE-----RGTTIVMATHNADIVNTIrHRVIAIEGGKI 215
Cdd:TIGR00957 792 DAHVG---KHIFEHVIGpegvlKNKTRILVTHGISYLPQV-DVIIVMSGGKI 839
|
|
| CFTR_protein |
TIGR01271 |
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ... |
21-176 |
6.51e-09 |
|
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]
Pssm-ID: 273530 [Multi-domain] Cd Length: 1490 Bit Score: 55.69 E-value: 6.51e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 21 LTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTietlaerdvpYFRRQLGVIfqdfklLPKlTVYENV 100
Cdd:TIGR01271 445 ISFKLEKGQLLAVAGSTGSGKSSLLMMIMGELEPSEGKIKHSGRI----------SFSPQTSWI------MPG-TIKDNI 507
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 101 SFALEVIEeepdairERVTEVLGLVGLEDRADALPSE-----------LSGGEQQRVAIARAIVNRPKVVIADEPTGNLD 169
Cdd:TIGR01271 508 IFGLSYDE-------YRYTSVIKACQLEEDIALFPEKdktvlgeggitLSGGQRARISLARAVYKDADLYLLDSPFTHLD 580
|
....*..
gi 446516975 170 IETALDI 176
Cdd:TIGR01271 581 VVTEKEI 587
|
|
| ABCC_CFTR1 |
cd03291 |
ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The ... |
21-176 |
1.89e-08 |
|
ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The CFTR subfamily domain 1. The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits, or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.
Pssm-ID: 213258 [Multi-domain] Cd Length: 282 Bit Score: 53.32 E-value: 1.89e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 21 LTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNG-LTIETLAERDVPYFRRQ---LGVIFQDFKllpkltv 96
Cdd:cd03291 56 INLKIEKGEMLAITGSTGSGKTSLLMLILGELEPSEGKIKHSGrISFSSQFSWIMPGTIKEniiFGVSYDEYR------- 128
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 97 YENVSFALEvIEEEPDAIRERVTEVLGLVGLedradalpsELSGGEQQRVAIARAIVNRPKVVIADEPTGNLDIETALDI 176
Cdd:cd03291 129 YKSVVKACQ-LEEDITKFPEKDNTVLGEGGI---------TLSGGQRARISLARAVYKDADLYLLDSPFGYLDVFTEKEI 198
|
|
| ABC_UvrA_II |
cd03271 |
ATP-binding cassette domain II of the excision repair protein UvrA; Nucleotide excision repair ... |
94-216 |
2.56e-08 |
|
ATP-binding cassette domain II of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins and UvrB having one ATP binding site that is structurally related to that of helicases.
Pssm-ID: 213238 [Multi-domain] Cd Length: 261 Bit Score: 53.00 E-value: 2.56e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 94 LTVYEnvsfALEVIEEEPdAIRERVtEVLGLVGLEDRADALPS-ELSGGEQQRVAIARAIVNR---PKVVIADEPTGNL- 168
Cdd:cd03271 131 MTVEE----ALEFFENIP-KIARKL-QTLCDVGLGYIKLGQPAtTLSGGEAQRIKLAKELSKRstgKTLYILDEPTTGLh 204
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*.
gi 446516975 169 --DIETALDIMNiftRINERGTTIVMATHNADIVNTIRHrVIAI------EGGKIV 216
Cdd:cd03271 205 fhDVKKLLEVLQ---RLVDKGNTVVVIEHNLDVIKCADW-IIDLgpeggdGGGQVV 256
|
|
| PRK15064 |
PRK15064 |
ABC transporter ATP-binding protein; Provisional |
6-216 |
2.60e-08 |
|
ABC transporter ATP-binding protein; Provisional
Pssm-ID: 237894 [Multi-domain] Cd Length: 530 Bit Score: 53.36 E-value: 2.60e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 6 NVYKEYPNGMkAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINvngltietLAER-DVPYFRRQLGVI 84
Cdd:PRK15064 324 NLTKGFDNGP-LFKNLNLLLEAGERLAIIGENGVGKTTLLRTLVGELEPDSGTVK--------WSENaNIGYYAQDHAYD 394
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 85 FQDfkllpKLTVYENVSfalEVIEEEPD--AIRErvteVLG-LVGLEDRADALPSELSGGEQQRVAIARAIVNRPKVVIA 161
Cdd:PRK15064 395 FEN-----DLTLFDWMS---QWRQEGDDeqAVRG----TLGrLLFSQDDIKKSVKVLSGGEKGRMLFGKLMMQKPNVLVM 462
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446516975 162 DEPTGNLDIE------TALDimniftriNERGTTIVMaTHNADIVNTIRHRVIAIEGGKIV 216
Cdd:PRK15064 463 DEPTNHMDMEsieslnMALE--------KYEGTLIFV-SHDREFVSSLATRIIEITPDGVV 514
|
|
| PRK10636 |
PRK10636 |
putative ABC transporter ATP-binding protein; Provisional |
1-171 |
3.45e-08 |
|
putative ABC transporter ATP-binding protein; Provisional
Pssm-ID: 236729 [Multi-domain] Cd Length: 638 Bit Score: 53.25 E-value: 3.45e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 1 MIKMTNVYKEYpnGMKAI-AGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINV-NGLTIETLAERDVPYFR 78
Cdd:PRK10636 312 LLKMEKVSAGY--GDRIIlDSIKLNLVPGSRIGLLGRNGAGKSTLIKLLAGELAPVSGEIGLaKGIKLGYFAQHQLEFLR 389
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 79 RQLGVIFQDFKLLPKLTvyenvsfalevieeepdaiRERVTEVLGLVGLE-DRADALPSELSGGEQQRVAIARAIVNRPK 157
Cdd:PRK10636 390 ADESPLQHLARLAPQEL-------------------EQKLRDYLGGFGFQgDKVTEETRRFSGGEKARLVLALIVWQRPN 450
|
170
....*....|....
gi 446516975 158 VVIADEPTGNLDIE 171
Cdd:PRK10636 451 LLLLDEPTNHLDLD 464
|
|
| PRK13549 |
PRK13549 |
xylose transporter ATP-binding subunit; Provisional |
138-215 |
3.45e-08 |
|
xylose transporter ATP-binding subunit; Provisional
Pssm-ID: 184134 [Multi-domain] Cd Length: 506 Bit Score: 53.01 E-value: 3.45e-08
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446516975 138 LSGGEQQRVAIARAIVNRPKVVIADEPTGNLDIETALDIMNIFTRINERGTTIVMATHNADIVNTIRHRVIAIEGGKI 215
Cdd:PRK13549 406 LSGGNQQKAVLAKCLLLNPKILILDEPTRGIDVGAKYEIYKLINQLVQQGVAIIVISSELPEVLGLSDRVLVMHEGKL 483
|
|
| CFTR_protein |
TIGR01271 |
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ... |
1-169 |
3.68e-08 |
|
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]
Pssm-ID: 273530 [Multi-domain] Cd Length: 1490 Bit Score: 53.38 E-value: 3.68e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 1 MIKMTNVYKEYPN-GMKAIAGLTV---------------NIKQGEFVYVVGPSGAGKSTFIKMMYREEKpSTGSINVNGL 64
Cdd:TIGR01271 1202 VIENPHAQKCWPSgGQMDVQGLTAkyteagravlqdlsfSVEGGQRVGLLGRTGSGKSTLLSALLRLLS-TEGEIQIDGV 1280
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 65 TIETLAerdVPYFRRQLGVIFQDFKLLPKlTVYENvsfaLEVIEEEPDAIRERVTEVlglVGLEDRADALPSEL------ 138
Cdd:TIGR01271 1281 SWNSVT---LQTWRKAFGVIPQKVFIFSG-TFRKN----LDPYEQWSDEEIWKVAEE---VGLKSVIEQFPDKLdfvlvd 1349
|
170 180 190
....*....|....*....|....*....|....*.
gi 446516975 139 -----SGGEQQRVAIARAIVNRPKVVIADEPTGNLD 169
Cdd:TIGR01271 1350 ggyvlSNGHKQLMCLARSILSKAKILLLDEPSAHLD 1385
|
|
| ABC_UvrA |
cd03238 |
ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in ... |
17-202 |
4.01e-08 |
|
ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins, and UvrB having one ATP binding site that is structurally related to that of helicases.
Pssm-ID: 213205 [Multi-domain] Cd Length: 176 Bit Score: 51.17 E-value: 4.01e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 17 AIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKpstgsinvngltiETLAERDVPYFRRQLGVIFQDFKLLPKLTv 96
Cdd:cd03238 10 NLQNLDVSIPLNVLVVVTGVSGSGKSTLVNEGLYASG-------------KARLISFLPKFSRNKLIFIDQLQFLIDVG- 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 97 yenvsfalevieeepdairervtevLGLVGLEDRAdalpSELSGGEQQRVAIARAIVNRPK--VVIADEPTGNLDIETAL 174
Cdd:cd03238 76 -------------------------LGYLTLGQKL----STLSGGELQRVKLASELFSEPPgtLFILDEPSTGLHQQDIN 126
|
170 180
....*....|....*....|....*...
gi 446516975 175 DIMNIFTRINERGTTIVMATHNADIVNT 202
Cdd:cd03238 127 QLLEVIKGLIDLGNTVILIEHNLDVLSS 154
|
|
| PLN03073 |
PLN03073 |
ABC transporter F family; Provisional |
11-171 |
1.27e-07 |
|
ABC transporter F family; Provisional
Pssm-ID: 215558 [Multi-domain] Cd Length: 718 Bit Score: 51.78 E-value: 1.27e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 11 YPNGMKAIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGsinvnglTIETLAERDVPYFRrQLGVIFQDFKL 90
Cdd:PLN03073 518 YPGGPLLFKNLNFGIDLDSRIAMVGPNGIGKSTILKLISGELQPSSG-------TVFRSAKVRMAVFS-QHHVDGLDLSS 589
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 91 LPKLtvYENVSFalevieeePDAIRERVTEVLGLVGLEDRADALPS-ELSGGEQQRVAIARAIVNRPKVVIADEPTGNLD 169
Cdd:PLN03073 590 NPLL--YMMRCF--------PGVPEQKLRAHLGSFGVTGNLALQPMyTLSGGQKSRVAFAKITFKKPHILLLDEPSNHLD 659
|
..
gi 446516975 170 IE 171
Cdd:PLN03073 660 LD 661
|
|
| uvra |
TIGR00630 |
excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of ... |
94-216 |
1.34e-07 |
|
excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of proteins of which all members for which functions are known except the UvrA proteins are involved in the transport of material through membranes. UvrA orthologs are involved in the recognition of DNA damage as a step in nucleotide excision repair. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273184 [Multi-domain] Cd Length: 925 Bit Score: 51.55 E-value: 1.34e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 94 LTVYEnvsfALEVIEEEPdAIReRVTEVLGLVGLEDRADALPS-ELSGGEQQRVAIARAIVNR---PKVVIADEPTGNLD 169
Cdd:TIGR00630 791 MTVEE----AYEFFEAVP-SIS-RKLQTLCDVGLGYIRLGQPAtTLSGGEAQRIKLAKELSKRstgRTLYILDEPTTGLH 864
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|...
gi 446516975 170 IETALDIMNIFTRINERGTTIVMATHNADIVNTIRHrVIAI------EGGKIV 216
Cdd:TIGR00630 865 FDDIKKLLEVLQRLVDKGNTVVVIEHNLDVIKTADY-IIDLgpeggdGGGTVV 916
|
|
| AAA |
smart00382 |
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ... |
27-199 |
1.45e-07 |
|
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.
Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 49.29 E-value: 1.45e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 27 QGEFVYVVGPSGAGKSTFIKMMYREekpstgsinvngltietlaerdvpYFRRQLGVIFQDfkllpkltvyenvsfalev 106
Cdd:smart00382 1 PGEVILIVGPPGSGKTTLARALARE------------------------LGPPGGGVIYID------------------- 37
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 107 ieeePDAIRERVTEVLGLVGLEDRadalPSELSGGEQQRVAIARAIVNRPKVVIADEPTGNLDIETALDIMNI------F 180
Cdd:smart00382 38 ----GEDILEEVLDQLLLIIVGGK----KASGSGELRLRLALALARKLKPDVLILDEITSLLDAEQEALLLLLeelrllL 109
|
170
....*....|....*....
gi 446516975 181 TRINERGTTIVMATHNADI 199
Cdd:smart00382 110 LLKSEKNLTVILTTNDEKD 128
|
|
| ABCC_CFTR2 |
cd03289 |
ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator ... |
2-169 |
3.75e-07 |
|
ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.
Pssm-ID: 213256 [Multi-domain] Cd Length: 275 Bit Score: 49.47 E-value: 3.75e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 2 IKMTNVYKEYPNGMKAI-AGLTVNIKQGEFVYVVGPSGAGKST----FIKMMYREekpstGSINVNGLTIETLAERDvpy 76
Cdd:cd03289 3 MTVKDLTAKYTEGGNAVlENISFSISPGQRVGLLGRTGSGKSTllsaFLRLLNTE-----GDIQIDGVSWNSVPLQK--- 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 77 FRRQLGVIFQDFKLLPKlTVYENvsfaLEVIEEEPDairERVTEVLGLVGLEDRADALPSEL-----------SGGEQQR 145
Cdd:cd03289 75 WRKAFGVIPQKVFIFSG-TFRKN----LDPYGKWSD---EEIWKVAEEVGLKSVIEQFPGQLdfvlvdggcvlSHGHKQL 146
|
170 180
....*....|....*....|....
gi 446516975 146 VAIARAIVNRPKVVIADEPTGNLD 169
Cdd:cd03289 147 MCLARSVLSKAKILLLDEPSAHLD 170
|
|
| PRK10636 |
PRK10636 |
putative ABC transporter ATP-binding protein; Provisional |
22-211 |
6.83e-07 |
|
putative ABC transporter ATP-binding protein; Provisional
Pssm-ID: 236729 [Multi-domain] Cd Length: 638 Bit Score: 49.40 E-value: 6.83e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 22 TVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSIN---------VNGLT-------IETLAERDVPYfrRQLGVIF 85
Cdd:PRK10636 21 TATINPGQKVGLVGKNGCGKSTLLALLKNEISADGGSYTfpgnwqlawVNQETpalpqpaLEYVIDGDREY--RQLEAQL 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 86 QDFKllpkltvYENVSFALEVIEEEPDA-----IRERVTEVLGLVGLEDRADALP-SELSGGEQQRVAIARAIVNRPKVV 159
Cdd:PRK10636 99 HDAN-------ERNDGHAIATIHGKLDAidawtIRSRAASLLHGLGFSNEQLERPvSDFSGGWRMRLNLAQALICRSDLL 171
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 446516975 160 IADEPTGNLDietaLDIMNIFTR-INERGTTIVMATHNADIVNTIRHRVIAIE 211
Cdd:PRK10636 172 LLDEPTNHLD----LDAVIWLEKwLKSYQGTLILISHDRDFLDPIVDKIIHIE 220
|
|
| PRK15064 |
PRK15064 |
ABC transporter ATP-binding protein; Provisional |
34-203 |
1.35e-06 |
|
ABC transporter ATP-binding protein; Provisional
Pssm-ID: 237894 [Multi-domain] Cd Length: 530 Bit Score: 48.35 E-value: 1.35e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 34 VGPSGAGKSTFIKMMYREEKPSTG--SINVNgltietlaERdvpyfrrqLGVIFQD-FkllpkltVYENVSFALEVI--- 107
Cdd:PRK15064 33 IGANGCGKSTFMKILGGDLEPSAGnvSLDPN--------ER--------LGKLRQDqF-------AFEEFTVLDTVImgh 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 108 ------EEEPDAI-----------------------------RERVTEVLGLVGL-EDRADALPSELSGGEQQRVAIARA 151
Cdd:PRK15064 90 telwevKQERDRIyalpemseedgmkvadlevkfaemdgytaEARAGELLLGVGIpEEQHYGLMSEVAPGWKLRVLLAQA 169
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 446516975 152 IVNRPKVVIADEPTGNLDIETaldIMNIFTRINERGTTIVMATHNADIVNTI 203
Cdd:PRK15064 170 LFSNPDILLLDEPTNNLDINT---IRWLEDVLNERNSTMIIISHDRHFLNSV 218
|
|
| ABC2_perm_RbbA |
NF033858 |
ribosome-associated ATPase/putative transporter RbbA; |
17-165 |
1.63e-06 |
|
ribosome-associated ATPase/putative transporter RbbA;
Pssm-ID: 468210 [Multi-domain] Cd Length: 907 Bit Score: 48.20 E-value: 1.63e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 17 AIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGLTIETLAERD-----VPYFRRQLGvifqdfK-L 90
Cdd:NF033858 16 ALDDVSLDIPAGCMVGLIGPDGVGKSSLLSLIAGARKIQQGRVEVLGGDMADARHRRavcprIAYMPQGLG------KnL 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 91 LPKLTVYENVSF-----ALEVIEEepdaiRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIVNRPKVVIADEPT 165
Cdd:NF033858 90 YPTLSVFENLDFfgrlfGQDAAER-----RRRIDELLRATGLAPFADRPAGKLSGGMKQKLGLCCALIHDPDLLILDEPT 164
|
|
| hmuV |
PRK13547 |
heme ABC transporter ATP-binding protein; |
21-170 |
3.74e-06 |
|
heme ABC transporter ATP-binding protein;
Pssm-ID: 184132 [Multi-domain] Cd Length: 272 Bit Score: 46.74 E-value: 3.74e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 21 LTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPS--------TGSINVNGltiETLAERDVPYFRRQLGVIFQDFKLLP 92
Cdd:PRK13547 20 LSLRIEPGRVTALLGRNGAGKSTLLKALAGDLTGGgaprgarvTGDVTLNG---EPLAAIDAPRLARLRAVLPQAAQPAF 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 93 KLTVYENVSFALEVIEEEPDAIRERVTEV----LGLVGledrADALP----SELSGGEQQRVAIARAIVN---------R 155
Cdd:PRK13547 97 AFSAREIVLLGRYPHARRAGALTHRDGEIawqaLALAG----ATALVgrdvTTLSGGELARVQFARVLAQlwpphdaaqP 172
|
170
....*....|....*
gi 446516975 156 PKVVIADEPTGNLDI 170
Cdd:PRK13547 173 PRYLLLDEPTAALDL 187
|
|
| PRK00635 |
PRK00635 |
excinuclease ABC subunit A; Provisional |
94-224 |
4.68e-06 |
|
excinuclease ABC subunit A; Provisional
Pssm-ID: 234806 [Multi-domain] Cd Length: 1809 Bit Score: 47.13 E-value: 4.68e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 94 LTVYENVSFALEvieeEPdAIRERVtEVLGLVGLedraDALP-----SELSGGEQQRVAIARAIVN---RPKVVIADEPT 165
Cdd:PRK00635 771 MTAYEAEKFFLD----EP-SIHEKI-HALCSLGL----DYLPlgrplSSLSGGEIQRLKLAYELLApskKPTLYVLDEPT 840
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446516975 166 GNLDIETALDIMNIFTRINERGTTIVMATHNADIVNTIRHrVIAI--EGGKIvrdeieGGY 224
Cdd:PRK00635 841 TGLHTHDIKALIYVLQSLTHQGHTVVIIEHNMHVVKVADY-VLELgpEGGNL------GGY 894
|
|
| ABC_UvrA_I |
cd03270 |
ATP-binding cassette domain I of the excision repair protein UvrA; Nucleotide excision repair ... |
21-216 |
5.14e-06 |
|
ATP-binding cassette domain I of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins, and UvrB having one ATP binding site that is structurally related to that of helicases.
Pssm-ID: 213237 [Multi-domain] Cd Length: 226 Bit Score: 45.71 E-value: 5.14e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 21 LTVNIKQGEFVYVVGPSGAGKSTF-IKMMYREEKPStgsinvnglTIETLAerdvPYFRRQLGVIFQdfkllPKLTVYEN 99
Cdd:cd03270 14 VDVDIPRNKLVVITGVSGSGKSSLaFDTIYAEGQRR---------YVESLS----AYARQFLGQMDK-----PDVDSIEG 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 100 VSFALEV----IEEEPDAIRERVTEV---LGL----VGLEDRADAL-------------PSELSGGEQQRVAIARAIVNR 155
Cdd:cd03270 76 LSPAIAIdqktTSRNPRSTVGTVTEIydyLRLlfarVGIRERLGFLvdvglgyltlsrsAPTLSGGEAQRIRLATQIGSG 155
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446516975 156 PKVV--IADEPTGNLDIETALDIMNIFTRINERGTTIVMATHNADivnTIRH--RVI------AIEGGKIV 216
Cdd:cd03270 156 LTGVlyVLDEPSIGLHPRDNDRLIETLKRLRDLGNTVLVVEHDED---TIRAadHVIdigpgaGVHGGEIV 223
|
|
| PLN03073 |
PLN03073 |
ABC transporter F family; Provisional |
139-216 |
2.37e-05 |
|
ABC transporter F family; Provisional
Pssm-ID: 215558 [Multi-domain] Cd Length: 718 Bit Score: 44.85 E-value: 2.37e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446516975 139 SGGEQQRVAIARAIVNRPKVVIADEPTGNLDIETALDIMNIFTRINErgtTIVMATHNADIVNTIRHRVIAIEGGKIV 216
Cdd:PLN03073 346 SGGWRMRIALARALFIEPDLLLLDEPTNHLDLHAVLWLETYLLKWPK---TFIVVSHAREFLNTVVTDILHLHGQKLV 420
|
|
| PRK10982 |
PRK10982 |
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional |
138-192 |
6.78e-05 |
|
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
Pssm-ID: 182880 [Multi-domain] Cd Length: 491 Bit Score: 43.18 E-value: 6.78e-05
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 446516975 138 LSGGEQQRVAIARAIVNRPKVVIADEPTGNLDIETALDIMNIFTRINERGTTIVM 192
Cdd:PRK10982 392 LSGGNQQKVIIGRWLLTQPEILMLDEPTRGIDVGAKFEIYQLIAELAKKDKGIII 446
|
|
| PRK13546 |
PRK13546 |
teichoic acids export ABC transporter ATP-binding subunit TagH; |
17-215 |
1.28e-04 |
|
teichoic acids export ABC transporter ATP-binding subunit TagH;
Pssm-ID: 184131 [Multi-domain] Cd Length: 264 Bit Score: 42.11 E-value: 1.28e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 17 AIAGLTVNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSINVNGltietlaerdvpyfrrQLGVIFQDFKLLPKLTV 96
Cdd:PRK13546 39 ALDDISLKAYEGDVIGLVGINGSGKSTLSNIIGGSLSPTVGKVDRNG----------------EVSVIAISAGLSGQLTG 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 97 YENVSFALEVIEEEPDAIRERVTEVLGLVGLEDRADALPSELSGGEQQRVAIARAIVNRPKVVIADEPTGNLDIETALDI 176
Cdd:PRK13546 103 IENIEFKMLCMGFKRKEIKAMTPKIIEFSELGEFIYQPVKKYSSGMRAKLGFSINITVNPDILVIDEALSVGDQTFAQKC 182
|
170 180 190
....*....|....*....|....*....|....*....
gi 446516975 177 MNIFTRINERGTTIVMATHNADIVNTIRHRVIAIEGGKI 215
Cdd:PRK13546 183 LDKIYEFKEQNKTIFFVSHNLGQVRQFCTKIAWIEGGKL 221
|
|
| UvrA |
COG0178 |
Excinuclease UvrABC ATPase subunit [Replication, recombination and repair]; |
138-216 |
1.46e-04 |
|
Excinuclease UvrABC ATPase subunit [Replication, recombination and repair];
Pssm-ID: 439948 [Multi-domain] Cd Length: 941 Bit Score: 42.32 E-value: 1.46e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 138 LSGGEQQRVAIARAIVNRPK---VVIADEPTGNL---DIETALDIMNiftRINERGTTIVMATHNADIVNTIRHrVIAI- 210
Cdd:COG0178 827 LSGGEAQRVKLASELSKRSTgktLYILDEPTTGLhfhDIRKLLEVLH---RLVDKGNTVVVIEHNLDVIKTADW-IIDLg 902
|
90
....*....|.
gi 446516975 211 -----EGGKIV 216
Cdd:COG0178 903 peggdGGGEIV 913
|
|
| uvrA |
PRK00349 |
excinuclease ABC subunit UvrA; |
138-216 |
1.62e-04 |
|
excinuclease ABC subunit UvrA;
Pssm-ID: 234734 [Multi-domain] Cd Length: 943 Bit Score: 42.37 E-value: 1.62e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 138 LSGGEQQRVAIARAIVNRPK---VVIADEPTGNL---DIETALDIMNiftRINERGTTIVMATHNADIVNTIRHrVIAI- 210
Cdd:PRK00349 831 LSGGEAQRVKLAKELSKRSTgktLYILDEPTTGLhfeDIRKLLEVLH---RLVDKGNTVVVIEHNLDVIKTADW-IIDLg 906
|
90
....*....|.
gi 446516975 211 -----EGGKIV 216
Cdd:PRK00349 907 peggdGGGEIV 917
|
|
| PRK10938 |
PRK10938 |
putative molybdenum transport ATP-binding protein ModF; Provisional |
23-192 |
1.71e-04 |
|
putative molybdenum transport ATP-binding protein ModF; Provisional
Pssm-ID: 182852 [Multi-domain] Cd Length: 490 Bit Score: 41.92 E-value: 1.71e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 23 VNIKQGEFVYVVGPSGAGKSTFIKMMYREEKPSTGSIN-----VNGLTIETLAERDVPYFRRQ----LGVIFQDFKLlpk 93
Cdd:PRK10938 24 LTLNAGDSWAFVGANGSGKSALARALAGELPLLSGERQsqfshITRLSFEQLQKLVSDEWQRNntdmLSPGEDDTGR--- 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 94 ltvyenvsFALEVIEEE-PDAIR-ERVTEVLGLVGLEDRADalpSELSGGEQQRVAIARAIVNRPKVVIADEPTGNLDIE 171
Cdd:PRK10938 101 --------TTAEIIQDEvKDPARcEQLAQQFGITALLDRRF---KYLSTGETRKTLLCQALMSEPDLLILDEPFDGLDVA 169
|
170 180
....*....|....*....|.
gi 446516975 172 TALDIMNIFTRINERGTTIVM 192
Cdd:PRK10938 170 SRQQLAELLASLHQSGITLVL 190
|
|
| uvra |
TIGR00630 |
excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of ... |
53-216 |
1.77e-04 |
|
excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of proteins of which all members for which functions are known except the UvrA proteins are involved in the transport of material through membranes. UvrA orthologs are involved in the recognition of DNA damage as a step in nucleotide excision repair. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273184 [Multi-domain] Cd Length: 925 Bit Score: 42.31 E-value: 1.77e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 53 KPSTGSINVNGLTIETLAERDVpyfrRQLGVIFQDFKLLPkltvyENVSFALEVIEEepdaIRERVTeVLGLVGLE---- 128
Cdd:TIGR00630 417 KPEALAVTVGGKSIADVSELSI----REAHEFFNQLTLTP-----EEKKIAEEVLKE----IRERLG-FLIDVGLDylsl 482
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 129 DRAdalPSELSGGEQQRVAIARAIVNRPKVV--IADEPTGNLDIETALDIMNIFTRINERGTTIVMATHNADivnTIRH- 205
Cdd:TIGR00630 483 SRA---AGTLSGGEAQRIRLATQIGSGLTGVlyVLDEPSIGLHQRDNRRLINTLKRLRDLGNTLIVVEHDED---TIRAa 556
|
170
....*....|....*...
gi 446516975 206 -RVI------AIEGGKIV 216
Cdd:TIGR00630 557 dYVIdigpgaGEHGGEVV 574
|
|
| ABC_Rad50 |
cd03240 |
ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ... |
33-214 |
2.11e-04 |
|
ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ATP-binding cassette of ABC transporters, but are not associated with membrane-spanning domains. The conserved ATP-binding motifs common to Rad50 and the ABC transporter family include the Walker A and Walker B motifs, the Q loop, a histidine residue in the switch region, a D-loop, and a conserved LSGG sequence. This conserved sequence, LSGG, is the most specific and characteristic motif of this family and is thus known as the ABC signature sequence.
Pssm-ID: 213207 [Multi-domain] Cd Length: 204 Bit Score: 41.05 E-value: 2.11e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 33 VVGPSGAGKSTFI---KMMYREEKPSTGSINVNGLTI----ETLAERDVpYFRRQLGVifqDFKLLPKLTVYENVSFale 105
Cdd:cd03240 27 IVGQNGAGKTTIIealKYALTGELPPNSKGGAHDPKLiregEVRAQVKL-AFENANGK---KYTITRSLAILENVIF--- 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 106 VIEEEPDAIrervtevlglvgLEDRADAlpseLSGGEQQ------RVAIARAIVNRPKVVIADEPTGNLD---IETAL-D 175
Cdd:cd03240 100 CHQGESNWP------------LLDMRGR----CSGGEKVlasliiRLALAETFGSNCGILALDEPTTNLDeenIEESLaE 163
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 446516975 176 IMNifTRINERGTTIVMATHNADIVNTIRH--RVIAIEGGK 214
Cdd:cd03240 164 IIE--ERKSQKNFQLIVITHDEELVDAADHiyRVEKDGRQK 202
|
|
| PRK00635 |
PRK00635 |
excinuclease ABC subunit A; Provisional |
82-216 |
3.14e-04 |
|
excinuclease ABC subunit A; Provisional
Pssm-ID: 234806 [Multi-domain] Cd Length: 1809 Bit Score: 41.35 E-value: 3.14e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 82 GVIFQDFKLLP--KLTVYEN-VSFALEVIEEEPDAIRERVTEV--LGLVGLE-DRADAlpsELSGGEQQRVAIARAIVNR 155
Cdd:PRK00635 418 GKTFAEFQQMSlqELFIFLSqLPSKSLSIEEVLQGLKSRLSILidLGLPYLTpERALA---TLSGGEQERTALAKHLGAE 494
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446516975 156 PKVV--IADEPTGNLDIETALDIMNIFTRINERGTTIVMATHNADIVnTIRHRVI------AIEGGKIV 216
Cdd:PRK00635 495 LIGItyILDEPSIGLHPQDTHKLINVIKKLRDQGNTVLLVEHDEQMI-SLADRIIdigpgaGIFGGEVL 562
|
|
| GguA |
NF040905 |
sugar ABC transporter ATP-binding protein; |
138-192 |
4.37e-04 |
|
sugar ABC transporter ATP-binding protein;
Pssm-ID: 468840 [Multi-domain] Cd Length: 500 Bit Score: 40.93 E-value: 4.37e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 446516975 138 LSGGEQQRVAIARAIVNRPKVVIADEPTGNLDIETALDIMNIFTRINERGTTIVM 192
Cdd:NF040905 405 LSGGNQQKVVLSKWLFTDPDVLILDEPTRGIDVGAKYEIYTIINELAAEGKGVIV 459
|
|
| SbcC |
COG0419 |
DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]; |
22-183 |
6.80e-04 |
|
DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair];
Pssm-ID: 440188 [Multi-domain] Cd Length: 204 Bit Score: 39.61 E-value: 6.80e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 22 TVNIKQGEFVyVVGPSGAGKSTFI-------------KMMYREEKPSTGSinvNGLTIE-TLAERDVPY--FRRQlGVIF 85
Cdd:COG0419 18 TIDFDDGLNL-IVGPNGAGKSTILeairyalygkarsRSKLRSDLINVGS---EEASVElEFEHGGKRYriERRQ-GEFA 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 86 QDFKLLPK-----------LTVYENVSFALEVIEEEPDAIRERVTEVLGLvgLEDRADAL-----PSELSGGEQQRVAIA 149
Cdd:COG0419 93 EFLEAKPSerkealkrllgLEIYEELKERLKELEEALESALEELAELQKL--KQEILAQLsgldpIETLSGGERLRLALA 170
|
170 180 190
....*....|....*....|....*....|....
gi 446516975 150 RAIvnrpkVVIADepTGNLDIETALDIMNIFTRI 183
Cdd:COG0419 171 DLL-----SLILD--FGSLDEERLERLLDALEEL 197
|
|
| ABC_Class2 |
cd03227 |
ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems ... |
138-205 |
1.02e-03 |
|
ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems involved in cellular processes other than transport. These families are characterized by the fact that the ABC subunit is made up of duplicated, fused ABC modules (ABC2). No known transmembrane proteins or domains are associated with these proteins.
Pssm-ID: 213194 [Multi-domain] Cd Length: 162 Bit Score: 38.49 E-value: 1.02e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446516975 138 LSGGEQQRVAIA-----RAIVNRPKVVIaDEPTGNLDIETALDIMNIFTRINERGTTIVMATHNADIVNTIRH 205
Cdd:cd03227 78 LSGGEKELSALAlilalASLKPRPLYIL-DEIDRGLDPRDGQALAEAILEHLVKGAQVIVITHLPELAELADK 149
|
|
| AAA_21 |
pfam13304 |
AAA domain, putative AbiEii toxin, Type IV TA system; Several members are annotated as being ... |
99-201 |
1.05e-03 |
|
AAA domain, putative AbiEii toxin, Type IV TA system; Several members are annotated as being of the abortive phage resistance system, in which case the family would be acting as the toxin for a type IV toxin-antitoxin resistance system.
Pssm-ID: 433102 [Multi-domain] Cd Length: 303 Bit Score: 39.30 E-value: 1.05e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 99 NVSFALEVIEEEPDAIRERVTEVLGLVGLEDRADALPSELSGGEQQ---RVAIARAIVNRPKVVIADEPTGNLDIETALD 175
Cdd:pfam13304 198 NLSDLGEGIEKSLLVDDRLRERGLILLENGGGGELPAFELSDGTKRllaLLAALLSALPKGGLLLIDEPESGLHPKLLRR 277
|
90 100
....*....|....*....|....*.
gi 446516975 176 IMNIFTRINERGTTIVMATHNADIVN 201
Cdd:pfam13304 278 LLELLKELSRNGAQLILTTHSPLLLD 303
|
|
| AAA_33 |
pfam13671 |
AAA domain; This family of domains contain only a P-loop motif, that is characteriztic of the ... |
31-118 |
3.83e-03 |
|
AAA domain; This family of domains contain only a P-loop motif, that is characteriztic of the AAA superfamily. Many of the proteins in this family are just short fragments so there is no Walker B motif.
Pssm-ID: 463952 [Multi-domain] Cd Length: 143 Bit Score: 36.52 E-value: 3.83e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446516975 31 VYVVGPSGAGKSTF------------------IKMMYREEKPS-TGSINVNGLTIETLAERDVPYFRRQLGVIFqDFKLL 91
Cdd:pfam13671 2 ILLVGLPGSGKSTLarrlleelgavrlssddeRKRLFGEGRPSiSYYTDATDRTYERLHELARIALRAGRPVIL-DATNL 80
|
90 100 110
....*....|....*....|....*....|....*
gi 446516975 92 ------PKLTVYE--NVSFALEVIEEEPDAIRERV 118
Cdd:pfam13671 81 rrderaRLLALAReyGVPVRIVVFEAPEEVLRERL 115
|
|
| PhnN |
COG3709 |
Ribose 1,5-bisphosphate kinase PhnN [Carbohydrate transport and metabolism]; |
28-45 |
6.07e-03 |
|
Ribose 1,5-bisphosphate kinase PhnN [Carbohydrate transport and metabolism];
Pssm-ID: 442923 Cd Length: 188 Bit Score: 36.32 E-value: 6.07e-03
|
| phosphon_PhnN |
TIGR02322 |
phosphonate metabolism protein/1,5-bisphosphokinase (PRPP-forming) PhnN; Members of this ... |
28-45 |
6.65e-03 |
|
phosphonate metabolism protein/1,5-bisphosphokinase (PRPP-forming) PhnN; Members of this family resemble PhnN of phosphonate utilization operons, where different such operons confer the ability to use somewhat different profiles of C-P bond-containing compounds (see ), including phosphites as well as phosphonates. PhnN in E. coli shows considerable homology to guanylate kinases (EC 2.7.4.8), and has actually been shown to act as a ribose 1,5-bisphosphokinase (PRPP forming). This suggests an analogous kinase reaction for phosphonate metabolism, converting 5-phosphoalpha-1-(methylphosphono)ribose to methylphosphono-PRPP. [Central intermediary metabolism, Phosphorus compounds]
Pssm-ID: 274078 Cd Length: 179 Bit Score: 36.19 E-value: 6.65e-03
|
| |
