|
Name |
Accession |
Description |
Interval |
E-value |
| TagH |
COG1134 |
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate ... |
1-216 |
8.26e-107 |
|
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440749 [Multi-domain] Cd Length: 245 Bit Score: 307.39 E-value: 8.26e-107
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 1 MIKIENLTKSYR------------------TPTGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKI 62
Cdd:COG1134 4 MIEVENVSKSYRlyhepsrslkelllrrrrTRREEFWALKDVSFEVERGESVGIIGRNGAGKSTLLKLIAGILEPTSGRV 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 63 ITNKTISWPVGLAGGFQGSLTGRENVKFVARLY-AKQEELKEKIEFVEEFAELGKYFDMPIKTYSSGMRSRLGFGLSMAF 141
Cdd:COG1134 84 EVNGRVSALLELGAGFHPELTGRENIYLNGRLLgLSRKEIDEKFDEIVEFAELGDFIDQPVKTYSSGMRARLAFAVATAV 163
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446512897 142 KFDYYIVDEVTAVGDARFKEKCAQLFKERHKES-SFLMVSHSLNSLKEFCDVAIVFKNSYIIgYYENVQSGIDEYK 216
Cdd:COG1134 164 DPDILLVDEVLAVGDAAFQKKCLARIRELRESGrTVIFVSHSMGAVRRLCDRAIWLEKGRLV-MDGDPEEVIAAYE 238
|
|
| ABC_KpsT_Wzt |
cd03220 |
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC ... |
2-204 |
4.65e-100 |
|
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC transporter subfamily is involved in extracellular polysaccharide export. Among the variety of membrane-linked or extracellular polysaccharides excreted by bacteria, only capsular polysaccharides, lipopolysaccharides, and teichoic acids have been shown to be exported by ABC transporters. A typical system is made of a conserved integral membrane and an ABC. In addition to these proteins, capsular polysaccharide exporter systems require two 'accessory' proteins to perform their function: a periplasmic (E.coli) or a lipid-anchored outer membrane protein called OMA (Neisseria meningitidis and Haemophilus influenza) and a cytoplasmic membrane protein MPA2.
Pssm-ID: 213187 [Multi-domain] Cd Length: 224 Bit Score: 289.43 E-value: 4.65e-100
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 2 IKIENLTKSYRTPT------------------GRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKII 63
Cdd:cd03220 1 IELENVSKSYPTYKggssslkklgilgrkgevGEFWALKDVSFEVPRGERIGLIGRNGAGKSTLLRLLAGIYPPDSGTVT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 64 TNKTISWPVGLAGGFQGSLTGRENVKFVARLY-AKQEELKEKIEFVEEFAELGKYFDMPIKTYSSGMRSRLGFGLSMAFK 142
Cdd:cd03220 81 VRGRVSSLLGLGGGFNPELTGRENIYLNGRLLgLSRKEIDEKIDEIIEFSELGDFIDLPVKTYSSGMKARLAFAIATALE 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446512897 143 FDYYIVDEVTAVGDARFKEKCAQLFKERHKE-SSFLMVSHSLNSLKEFCDVAIVFKNSYIIGY 204
Cdd:cd03220 161 PDILLIDEVLAVGDAAFQEKCQRRLRELLKQgKTVILVSHDPSSIKRLCDRALVLEKGKIRFD 223
|
|
| CcmA |
COG1131 |
ABC-type multidrug transport system, ATPase component [Defense mechanisms]; |
2-202 |
4.17e-41 |
|
ABC-type multidrug transport system, ATPase component [Defense mechanisms];
Pssm-ID: 440746 [Multi-domain] Cd Length: 236 Bit Score: 139.81 E-value: 4.17e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 2 IKIENLTKSYrtptGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKI------ITNKTISW--PVG 73
Cdd:COG1131 1 IEVRGLTKRY----GDKTALDGVSLTVEPGEIFGLLGPNGAGKTTTIRMLLGLLRPTSGEVrvlgedVARDPAEVrrRIG 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 74 L---AGGFQGSLTGRENVKFVARLY-AKQEELKEKIEFVEEFAELGKYFDMPIKTYSSGMRSRLGFGLSMAFKFDYYIVD 149
Cdd:COG1131 77 YvpqEPALYPDLTVRENLRFFARLYgLPRKEARERIDELLELFGLTDAADRKVGTLSGGMKQRLGLALALLHDPELLILD 156
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 446512897 150 EVTA----VGDARFKEKCAQLFKERHkesSFLMVSHSLNSLKEFCDVAIVFKNSYII 202
Cdd:COG1131 157 EPTSgldpEARRELWELLRELAAEGK---TVLLSTHYLEEAERLCDRVAIIDKGRIV 210
|
|
| NatA |
COG4555 |
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, ... |
1-214 |
1.03e-38 |
|
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, Inorganic ion transport and metabolism];
Pssm-ID: 443618 [Multi-domain] Cd Length: 243 Bit Score: 133.83 E-value: 1.03e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 1 MIKIENLTKSYrtptGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKII---TNKTISWP-----V 72
Cdd:COG4555 1 MIEVENLSKKY----GKVPALKDVSFTAKDGEITGLLGPNGAGKTTLLRMLAGLLKPDSGSILidgEDVRKEPRearrqI 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 73 GLAGGFQGS---LTGRENVKFVARLYA-KQEELKEKIEFVEEFAELGKYFDMPIKTYSSGMRSRLGFGLSMAFKFDYYIV 148
Cdd:COG4555 77 GVLPDERGLydrLTVRENIRYFAELYGlFDEELKKRIEELIELLGLEEFLDRRVGELSTGMKKKVALARALVHDPKVLLL 156
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446512897 149 DEVTAVGDARFKEKCAQLFKE-RHKESSFLMVSHSLNSLKEFCDVAIVFKNSYIIgyYENVQSGIDE 214
Cdd:COG4555 157 DEPTNGLDVMARRLLREILRAlKKEGKTVLFSSHIMQEVEALCDRVVILHKGKVV--AQGSLDELRE 221
|
|
| tagH |
PRK13545 |
teichoic acids export protein ATP-binding subunit; Provisional |
2-224 |
3.00e-36 |
|
teichoic acids export protein ATP-binding subunit; Provisional
Pssm-ID: 184130 [Multi-domain] Cd Length: 549 Bit Score: 133.48 E-value: 3.00e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 2 IKIENLTKSY---------------RTPTGR-HYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKIITN 65
Cdd:PRK13545 5 VKFEHVTKKYkmynkpfdklkdlffRSKDGEyHYALNNISFEVPEGEIVGIIGLNGSGKSTLSNLIAGVTMPNKGTVDIK 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 66 KTISWpVGLAGGFQGSLTGRENVKFVARLYA-KQEELKEKIEFVEEFAELGKYFDMPIKTYSSGMRSRLGFGLSMAFKFD 144
Cdd:PRK13545 85 GSAAL-IAISSGLNGQLTGIENIELKGLMMGlTKEKIKEIIPEIIEFADIGKFIYQPVKTYSSGMKSRLGFAISVHINPD 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 145 YYIVDEVTAVGDARFKEKCAQL---FKERHKESSFlmVSHSLNSLKEFCDVAIVFKNSYiIGYYENVQSGIDEY----KM 217
Cdd:PRK13545 164 ILVIDEALSVGDQTFTKKCLDKmneFKEQGKTIFF--ISHSLSQVKSFCTKALWLHYGQ-VKEYGDIKEVVDHYdeflKK 240
|
....*..
gi 446512897 218 YQALDIE 224
Cdd:PRK13545 241 YNQMSVE 247
|
|
| ABC_BcrA_bacitracin_resist |
cd03268 |
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily ... |
2-202 |
1.58e-35 |
|
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily represents ABC transporters involved in peptide antibiotic resistance. Bacitracin is a dodecapeptide antibiotic produced by B. licheniformis and B. subtilis. The synthesis of bacitracin is non-ribosomally catalyzed by a multi-enzyme complex BcrABC. Bacitracin has potent antibiotic activity against gram-positive bacteria. The inhibition of peptidoglycan biosynthesis is the best characterized bacterial effect of bacitracin. The bacitracin resistance of B. licheniformis is mediated by the ABC transporter Bcr which is composed of two identical BcrA ATP-binding subunits and one each of the integral membrane proteins, BcrB and BcrC. B. subtilis cells carrying bcr genes on high-copy number plasmids develop collateral detergent sensitivity, a similar phenomenon in human cells with overexpressed multi-drug resistance P-glycoprotein.
Pssm-ID: 213235 [Multi-domain] Cd Length: 208 Bit Score: 124.64 E-value: 1.58e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 2 IKIENLTKSYrtptGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKI-----ITNKTISWP--VGL 74
Cdd:cd03268 1 LKTNDLTKTY----GKKRVLDDISLHVKKGEIYGFLGPNGAGKTTTMKIILGLIKPDSGEItfdgkSYQKNIEALrrIGA 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 75 ---AGGFQGSLTGRENVKFVARLYAKqeeLKEKIEFVEEFAELGKYFDMPIKTYSSGMRSRLGFGLSMAFKFDYYIVDEV 151
Cdd:cd03268 77 lieAPGFYPNLTARENLRLLARLLGI---RKKRIDEVLDVVGLKDSAKKKVKGFSLGMKQRLGIALALLGNPDLLILDEP 153
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 446512897 152 TAVGDAR-FKEKCAQLFKERHKESSFLMVSHSLNSLKEFCDVAIVFKNSYII 202
Cdd:cd03268 154 TNGLDPDgIKELRELILSLRDQGITVLISSHLLSEIQKVADRIGIINKGKLI 205
|
|
| PRK13546 |
PRK13546 |
teichoic acids export ABC transporter ATP-binding subunit TagH; |
2-190 |
4.13e-34 |
|
teichoic acids export ABC transporter ATP-binding subunit TagH;
Pssm-ID: 184131 [Multi-domain] Cd Length: 264 Bit Score: 122.62 E-value: 4.13e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 2 IKIENLTKSYR-------------TPTGRH---YVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKIITN 65
Cdd:PRK13546 5 VNIKNVTKEYRiyrtnkermkdalIPKHKNktfFALDDISLKAYEGDVIGLVGINGSGKSTLSNIIGGSLSPTVGKVDRN 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 66 KTISwPVGLAGGFQGSLTGRENVKFVARLYA-KQEELKEKIEFVEEFAELGKYFDMPIKTYSSGMRSRLGFGLSMAFKFD 144
Cdd:PRK13546 85 GEVS-VIAISAGLSGQLTGIENIEFKMLCMGfKRKEIKAMTPKIIEFSELGEFIYQPVKKYSSGMRAKLGFSINITVNPD 163
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 446512897 145 YYIVDEVTAVGDARFKEKC---AQLFKERHKesSFLMVSHSLNSLKEFC 190
Cdd:PRK13546 164 ILVIDEALSVGDQTFAQKCldkIYEFKEQNK--TIFFVSHNLGQVRQFC 210
|
|
| CcmA |
COG4133 |
ABC-type transport system involved in cytochrome c biogenesis, ATPase component ... |
1-181 |
4.23e-33 |
|
ABC-type transport system involved in cytochrome c biogenesis, ATPase component [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 443308 [Multi-domain] Cd Length: 206 Bit Score: 118.35 E-value: 4.23e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 1 MIKIENLTKSYrtptGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKI------ITNKTISWP--- 71
Cdd:COG4133 2 MLEAENLSCRR----GERLLFSGLSFTLAAGEALALTGPNGSGKTTLLRILAGLLPPSAGEVlwngepIRDAREDYRrrl 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 72 --VGLAGGFQGSLTGRENVKFVARLYAKQEElKEKIEFVEEFAELGKYFDMPIKTYSSGMRSRLGFGLSMAFKFDYYIVD 149
Cdd:COG4133 78 ayLGHADGLKPELTVRENLRFWAALYGLRAD-REAIDEALEAVGLAGLADLPVRQLSAGQKRRVALARLLLSPAPLWLLD 156
|
170 180 190
....*....|....*....|....*....|....
gi 446512897 150 EVTAVGDARFKEKCAQLFkERHKES--SFLMVSH 181
Cdd:COG4133 157 EPFTALDAAGVALLAELI-AAHLARggAVLLTTH 189
|
|
| ABC_ATPase |
cd00267 |
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large ... |
3-198 |
1.16e-31 |
|
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213179 [Multi-domain] Cd Length: 157 Bit Score: 113.11 E-value: 1.16e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 3 KIENLTKSYrtptGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKIItnktiswpvglaggFQGSL 82
Cdd:cd00267 1 EIENLSFRY----GGRTALDNVSLTLKAGEIVALVGPNGSGKSTLLRAIAGLLKPTSGEIL--------------IDGKD 62
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 83 TGRENVKfvarlyakqeELKEKIEFVEEFaelgkyfdmpiktySSGMRSRLGFGLSMAFKFDYYIVDEVTAVGDARFKEK 162
Cdd:cd00267 63 IAKLPLE----------ELRRRIGYVPQL--------------SGGQRQRVALARALLLNPDLLLLDEPTSGLDPASRER 118
|
170 180 190
....*....|....*....|....*....|....*..
gi 446512897 163 CAQLFKERHKE-SSFLMVSHSLNSLKEFCDVAIVFKN 198
Cdd:cd00267 119 LLELLRELAEEgRTVIIVTHDPELAELAADRVIVLKD 155
|
|
| ABC_subfamily_A |
cd03263 |
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily ... |
2-195 |
2.59e-31 |
|
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily mediates the transport of a variety of lipid compounds. Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency, degenerative retinopathies, and congenital keratinization disorders. The ABCA1 protein is involved in disorders of cholesterol transport and high-density lipoprotein (HDL) biosynthesis. The ABCA4 (ABCR) protein transports vitamin A derivatives in the outer segments of photoreceptor cells, and therefore, performs a crucial step in the visual cycle. The ABCA genes are not present in yeast. However, evolutionary studies of ABCA genes indicate that they arose as transporters that subsequently duplicated and that certain sets of ABCA genes were lost in different eukaryotic lineages.
Pssm-ID: 213230 [Multi-domain] Cd Length: 220 Bit Score: 114.14 E-value: 2.59e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 2 IKIENLTKSYrtPTGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKIITN--------KTISWPVG 73
Cdd:cd03263 1 LQIRNLTKTY--KKGTKPAVDDLSLNVYKGEIFGLLGHNGAGKTTTLKMLTGELRPTSGTAYINgysirtdrKAARQSLG 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 74 LAGGFQ---GSLTGRENVKFVARLYAK-QEELKEKIEFVEEFAELGKYFDMPIKTYSSGMRSRLGFGLSMAFKFDYYIVD 149
Cdd:cd03263 79 YCPQFDalfDELTVREHLRFYARLKGLpKSEIKEEVELLLRVLGLTDKANKRARTLSGGMKRKLSLAIALIGGPSVLLLD 158
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 446512897 150 EVTAVGDARFKEKCAQLFKERHKESSFLMVSHSLNSLKEFCD-VAIV 195
Cdd:cd03263 159 EPTSGLDPASRRAIWDLILEVRKGRSIILTTHSMDEAEALCDrIAIM 205
|
|
| ABC_DR_subfamily_A |
cd03230 |
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily ... |
2-198 |
2.88e-30 |
|
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; This family of ATP-binding proteins belongs to a multi-subunit transporter involved in drug resistance (BcrA and DrrA), nodulation, lipid transport, and lantibiotic immunity. In bacteria and archaea, these transporters usually include an ATP-binding protein and one or two integral membrane proteins. Eukaryotic systems of the ABCA subfamily display ABC domains that are quite similar to this family. The ATP-binding domain shows the highest similarity between all members of the ABC transporter family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213197 [Multi-domain] Cd Length: 173 Bit Score: 110.18 E-value: 2.88e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 2 IKIENLTKSYrtptGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKIITNKTISWPVGLA------ 75
Cdd:cd03230 1 IEVRNLSKRY----GKKTALDDISLTVEKGEIYGLLGPNGAGKTTLIKIILGLLKPDSGEIKVLGKDIKKEPEEvkrrig 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 76 -----GGFQGSLTGRENVKfvarlyakqeelkekiefveefaelgkyfdmpiktYSSGMRSRLGFGLSMAFKFDYYIVDE 150
Cdd:cd03230 77 ylpeePSLYENLTVRENLK-----------------------------------LSGGMKQRLALAQALLHDPELLILDE 121
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 446512897 151 VTAVGDARFKEKCAQLFKERHKE-SSFLMVSHSLNSLKEFCDVAIVFKN 198
Cdd:cd03230 122 PTSGLDPESRREFWELLRELKKEgKTILLSSHILEEAERLCDRVAILNN 170
|
|
| ABC_cobalt_CbiO_domain1 |
cd03225 |
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ... |
3-198 |
5.45e-30 |
|
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.
Pssm-ID: 213192 [Multi-domain] Cd Length: 211 Bit Score: 110.25 E-value: 5.45e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 3 KIENLTKSYrtPTGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKIITN---------KTISWPVG 73
Cdd:cd03225 1 ELKNLSFSY--PDGARPALDDISLTIKKGEFVLIVGPNGSGKSTLLRLLNGLLGPTSGEVLVDgkdltklslKELRRKVG 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 74 LAggFQGS------LTGRENVKFVAR-LYAKQEELKEKIEFVEEFAELGKYFDMPIKTYSSGMRSRLGFGLSMAFKFDYY 146
Cdd:cd03225 79 LV--FQNPddqffgPTVEEEVAFGLEnLGLPEEEIEERVEEALELVGLEGLRDRSPFTLSGGQKQRVAIAGVLAMDPDIL 156
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 446512897 147 IVDEVTAVGDARFKEKCAQLFKERHKE-SSFLMVSHSLNSLKEFCDVAIVFKN 198
Cdd:cd03225 157 LLDEPTAGLDPAGRRELLELLKKLKAEgKTIIIVTHDLDLLLELADRVIVLED 209
|
|
| ABC_DrrA |
cd03265 |
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein ... |
2-195 |
3.23e-29 |
|
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein component of a bacterial exporter complex that confers resistance to the antibiotics daunorubicin and doxorubicin. In addition to DrrA, the complex includes an integral membrane protein called DrrB. DrrA belongs to the ABC family of transporters and shares sequence and functional similarities with a protein found in cancer cells called P-glycoprotein. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213232 [Multi-domain] Cd Length: 220 Bit Score: 108.61 E-value: 3.23e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 2 IKIENLTKSYrtptGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKIITN------------KTIS 69
Cdd:cd03265 1 IEVENLVKKY----GDFEAVRGVSFRVRRGEIFGLLGPNGAGKTTTIKMLTTLLKPTSGRATVAghdvvreprevrRRIG 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 70 WpVGLAGGFQGSLTGRENVKFVARLYA-KQEELKEKIEFVEEFAELGKYFDMPIKTYSSGMRSRLGFGLSMAFKFDYYIV 148
Cdd:cd03265 77 I-VFQDLSVDDELTGWENLYIHARLYGvPGAERRERIDELLDFVGLLEAADRLVKTYSGGMRRRLEIARSLVHRPEVLFL 155
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 446512897 149 DEVTAVGDARFKEKCAQLFKERHKES--SFLMVSHSLNSLKEFCD-VAIV 195
Cdd:cd03265 156 DEPTIGLDPQTRAHVWEYIEKLKEEFgmTILLTTHYMEEAEQLCDrVAII 205
|
|
| MlaF |
COG1127 |
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall ... |
1-202 |
1.21e-26 |
|
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440744 [Multi-domain] Cd Length: 241 Bit Score: 102.37 E-value: 1.21e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 1 MIKIENLTKSYrtptGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKI-ITNKTISwpvGLAGG-- 77
Cdd:COG1127 5 MIEVRNLTKSF----GDRVVLDGVSLDVPRGEILAIIGGSGSGKSVLLKLIIGLLRPDSGEIlVDGQDIT---GLSEKel 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 78 ----------FQG-----SLTGRENVKFVARLYAK--QEELKEKIEFVEEFAELGKYFD-MP--IktySSGMRSRLGFGL 137
Cdd:COG1127 78 yelrrrigmlFQGgalfdSLTVFENVAFPLREHTDlsEAEIRELVLEKLELVGLPGAADkMPseL---SGGMRKRVALAR 154
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446512897 138 SMAFKFDYYIVDEVTA----VGDARFkekcAQLFKERHKE--SSFLMVSHSLNSLKEFCDVAIVFKNSYII 202
Cdd:COG1127 155 ALALDPEILLYDEPTAgldpITSAVI----DELIRELRDElgLTSVVVTHDLDSAFAIADRVAVLADGKII 221
|
|
| ABC_Org_Solvent_Resistant |
cd03261 |
ATP-binding cassette transport system involved in resistance to organic solvents; ABC ... |
2-203 |
2.57e-26 |
|
ATP-binding cassette transport system involved in resistance to organic solvents; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213228 [Multi-domain] Cd Length: 235 Bit Score: 101.42 E-value: 2.57e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 2 IKIENLTKSYrtptGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKIITNKTISWPVGLAG----- 76
Cdd:cd03261 1 IELRGLTKSF----GGRTVLKGVDLDVRRGEILAIIGPSGSGKSTLLRLIVGLLRPDSGEVLIDGEDISGLSEAElyrlr 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 77 ---G--FQG-----SLTGRENVKFVARLYAK--QEELKEKIEFVEEFAELGKYFD-MPIKTySSGMRSRLGFGLSMAFKF 143
Cdd:cd03261 77 rrmGmlFQSgalfdSLTVFENVAFPLREHTRlsEEEIREIVLEKLEAVGLRGAEDlYPAEL-SGGMKKRVALARALALDP 155
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446512897 144 DYYIVDEVTAVGDARFKEKCAQLFKERHKE--SSFLMVSHSLNSLKEFCDVAIVFKNSYIIG 203
Cdd:cd03261 156 ELLLYDEPTAGLDPIASGVIDDLIRSLKKElgLTSIMVTHDLDTAFAIADRIAVLYDGKIVA 217
|
|
| ABC_Mj1267_LivG_branched |
cd03219 |
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ... |
2-196 |
6.48e-25 |
|
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ABC transporter subfamily is involved in the transport of the hydrophobic amino acids leucine, isoleucine and valine. MJ1267 is a branched-chain amino acid transporter with 29% similarity to both the LivF and LivG components of the E. coli branched-chain amino acid transporter. MJ1267 contains an insertion from residues 114 to 123 characteristic of LivG (Leucine-Isoleucine-Valine) homologs. The branched-chain amino acid transporter from E. coli comprises a heterodimer of ABCs (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ).
Pssm-ID: 213186 [Multi-domain] Cd Length: 236 Bit Score: 97.89 E-value: 6.48e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 2 IKIENLTKSYrtptGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKI------ITNktisWPV--- 72
Cdd:cd03219 1 LEVRGLTKRF----GGLVALDDVSFSVRPGEIHGLIGPNGAGKTTLFNLISGFLRPTSGSVlfdgedITG----LPPhei 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 73 ---GLAGGFQ-----GSLTGRENVK-----------FVARLYAKQEELKEKIEFVEEFAELGKYFDMPIKTYSSGMRSRL 133
Cdd:cd03219 73 arlGIGRTFQiprlfPELTVLENVMvaaqartgsglLLARARREEREARERAEELLERVGLADLADRPAGELSYGQQRRL 152
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446512897 134 GFGLSMAFKFDYYIVDEVTA-VGDARfKEKCAQLFKE-RHKESSFLMVSHSLNSLKEFCDVAIVF 196
Cdd:cd03219 153 EIARALATDPKLLLLDEPAAgLNPEE-TEELAELIRElRERGITVLLVEHDMDVVMSLADRVTVL 216
|
|
| ABC_MJ0796_LolCDE_FtsE |
cd03255 |
ATP-binding cassette domain of the transporters involved in export of lipoprotein and ... |
2-198 |
8.85e-25 |
|
ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and Cell division ATP-binding protein FtsE; This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.
Pssm-ID: 213222 [Multi-domain] Cd Length: 218 Bit Score: 97.18 E-value: 8.85e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 2 IKIENLTKSYRTPTGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKI-ITNKTISwpvGLAGG--- 77
Cdd:cd03255 1 IELKNLSKTYGGGGEKVQALKGVSLSIEKGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVrVDGTDIS---KLSEKela 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 78 ----------FQ-----GSLTGRENVKFVARLYA-KQEELKEKIEFVEEFAELGKYFDMPIKTYSSGMRSRLGFGLSMAF 141
Cdd:cd03255 78 afrrrhigfvFQsfnllPDLTALENVELPLLLAGvPKKERRERAEELLERVGLGDRLNHYPSELSGGQQQRVAIARALAN 157
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 446512897 142 KFDYYIVDEVTAVGDARFKEKCAQLFKERHKES--SFLMVSHSlNSLKEFCDVAIVFKN 198
Cdd:cd03255 158 DPKIILADEPTGNLDSETGKEVMELLRELNKEAgtTIVVVTHD-PELAEYADRIIELRD 215
|
|
| ABC_putative_ATPase |
cd03269 |
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the ... |
2-204 |
9.47e-25 |
|
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the subfamily A transporters involved in drug resistance, nodulation, lipid transport, and bacteriocin and lantibiotic immunity. In eubacteria and archaea, the typical organization consists of one ABC and one or two integral membranes. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213236 [Multi-domain] Cd Length: 210 Bit Score: 96.58 E-value: 9.47e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 2 IKIENLTKSYrtptGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKI-ITNKTISWPVGLAGGF-- 78
Cdd:cd03269 1 LEVENVTKRF----GRVTALDDISFSVEKGEIFGLLGPNGAGKTTTIRMILGIILPDSGEVlFDGKPLDIAARNRIGYlp 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 79 --QG---SLTGRENVKFVARLYA--KQEELKEKIEFVEEFaELGKYFDMPIKTYSSGMRSRLGFGLSMAFKFDYYIVDEV 151
Cdd:cd03269 77 eeRGlypKMKVIDQLVYLAQLKGlkKEEARRRIDEWLERL-ELSEYANKRVEELSKGNQQKVQFIAAVIHDPELLILDEP 155
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 446512897 152 TA----VGDARFKEKCAQLfkeRHKESSFLMVSHSLNSLKEFCDVAIVFKNSYIIGY 204
Cdd:cd03269 156 FSgldpVNVELLKDVIREL---ARAGKTVILSTHQMELVEELCDRVLLLNKGRAVLY 209
|
|
| ABC_NrtD_SsuB_transporters |
cd03293 |
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ... |
2-183 |
1.62e-24 |
|
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ATP-binding subunits of the bacterial ABC-type nitrate and sulfonate transport systems, respectively. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213260 [Multi-domain] Cd Length: 220 Bit Score: 96.39 E-value: 1.62e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 2 IKIENLTKSYRTPTGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKIITNKTISWPVGLAGG--FQ 79
Cdd:cd03293 1 LEVRNVSKTYGGGGGAVTALEDISLSVEEGEFVALVGPSGCGKSTLLRIIAGLERPTSGEVLVDGEPVTGPGPDRGyvFQ 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 80 GS-----LTGRENVKFVARL-YAKQEELKEKIEFVEEFAELGKYFDMPIKTYSSGMRSRLGFGLSMAFKFDYYIVDEVTA 153
Cdd:cd03293 81 QDallpwLTVLDNVALGLELqGVPKAEARERAEELLELVGLSGFENAYPHQLSGGMRQRVALARALAVDPDVLLLDEPFS 160
|
170 180 190
....*....|....*....|....*....|..
gi 446512897 154 VGDARFKEKCAQLFKE--RHKESSFLMVSHSL 183
Cdd:cd03293 161 ALDALTREQLQEELLDiwRETGKTVLLVTHDI 192
|
|
| EcfA2 |
COG1122 |
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and ... |
2-198 |
1.87e-24 |
|
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and metabolism, General function prediction only];
Pssm-ID: 440739 [Multi-domain] Cd Length: 230 Bit Score: 96.25 E-value: 1.87e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 2 IKIENLTKSYRtptGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKIITN---------KTISWPV 72
Cdd:COG1122 1 IELENLSFSYP---GGTPALDDVSLSIEKGEFVAIIGPNGSGKSTLLRLLNGLLKPTSGEVLVDgkditkknlRELRRKV 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 73 GLAggFQG------SLTGRENVKFVAR-LYAKQEELKEKIEFVEEFAELGKYFDMPIKTYSSGMRSRLGFGLSMAFKFDY 145
Cdd:COG1122 78 GLV--FQNpddqlfAPTVEEDVAFGPEnLGLPREEIRERVEEALELVGLEHLADRPPHELSGGQKQRVAIAGVLAMEPEV 155
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 446512897 146 YIVDEVTAVGDARFKEKCAQLFKERHKE-SSFLMVSHSLNSLKEFCDVAIVFKN 198
Cdd:COG1122 156 LVLDEPTAGLDPRGRRELLELLKRLNKEgKTVIIVTHDLDLVAELADRVIVLDD 209
|
|
| ABC_NikE_OppD_transporters |
cd03257 |
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter ... |
1-202 |
4.42e-24 |
|
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter subfamily specific for the transport of dipeptides, oligopeptides (OppD), and nickel (NikDE). The NikABCDE system of E. coli belongs to this family and is composed of the periplasmic binding protein NikA, two integral membrane components (NikB and NikC), and two ATPase (NikD and NikE). The NikABCDE transporter is synthesized under anaerobic conditions to meet the increased demand for nickel resulting from hydrogenase synthesis. The molecular mechanism of nickel uptake in many bacteria and most archaea is not known. Many other members of this ABC family are also involved in the uptake of dipeptides and oligopeptides. The oligopeptide transport system (Opp) is a five-component ABC transport composed of a membrane-anchored substrate binding proteins (SRP), OppA, two transmembrane proteins, OppB and OppC, and two ATP-binding domains, OppD and OppF.
Pssm-ID: 213224 [Multi-domain] Cd Length: 228 Bit Score: 95.27 E-value: 4.42e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 1 MIKIENLTKSYRTPTGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKIITNKTISWPVGLAGG--- 77
Cdd:cd03257 1 LLEVKNLSVSFPTGGGSVKALDDVSFSIKKGETLGLVGESGSGKSTLARAILGLLKPTSGSIIFDGKDLLKLSRRLRkir 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 78 -------FQ---GSLTGRENVK-------FVARLYAKQEELKEKIEfvEEFAELG---KYFDMPIKTYSSGMRSRLGFGL 137
Cdd:cd03257 81 rkeiqmvFQdpmSSLNPRMTIGeqiaeplRIHGKLSKKEARKEAVL--LLLVGVGlpeEVLNRYPHELSGGQRQRVAIAR 158
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446512897 138 SMAFKFDYYIVDEVTAVGDARFKEKCAQLFKERHKES--SFLMVSHSLNSLKEFCDVAIVFKNSYII 202
Cdd:cd03257 159 ALALNPKLLIADEPTSALDVSVQAQILDLLKKLQEELglTLLFITHDLGVVAKIADRVAVMYAGKIV 225
|
|
| TauB |
COG1116 |
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion ... |
1-132 |
5.53e-24 |
|
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440733 [Multi-domain] Cd Length: 260 Bit Score: 95.93 E-value: 5.53e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 1 MIKIENLTKSYRTPTGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKI-ITNKTISWP---VGLAg 76
Cdd:COG1116 7 ALELRGVSKRFPTGGGGVTALDDVSLTVAAGEFVALVGPSGCGKSTLLRLIAGLEKPTSGEVlVDGKPVTGPgpdRGVV- 85
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446512897 77 gFQGS-----LTGRENVKFVARLyaKQEELKEKIEFVEEFAEL-------GKYfdmPiKTYSSGMRSR 132
Cdd:COG1116 86 -FQEPallpwLTVLDNVALGLEL--RGVPKAERRERARELLELvglagfeDAY---P-HQLSGGMRQR 146
|
|
| ABC_Carb_Solutes_like |
cd03259 |
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is ... |
2-184 |
6.14e-24 |
|
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is comprised of proteins involved in the transport of apparently unrelated solutes and proteins specific for di- and oligosaccharides and polyols. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213226 [Multi-domain] Cd Length: 213 Bit Score: 94.51 E-value: 6.14e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 2 IKIENLTKSYrtptGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKI-ITNKTIS-WP-----VGL 74
Cdd:cd03259 1 LELKGLSKTY----GSVRALDDLSLTVEPGEFLALLGPSGCGKTTLLRLIAGLERPDSGEIlIDGRDVTgVPperrnIGM 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 75 AggFQG-----SLTGRENVKFVARLYA-KQEELKEKIEFVEEFAELGKYFDMPIKTYSSGMRSRLGFGLSMAFKFDYYIV 148
Cdd:cd03259 77 V--FQDyalfpHLTVAENIAFGLKLRGvPKAEIRARVRELLELVGLEGLLNRYPHELSGGQQQRVALARALAREPSLLLL 154
|
170 180 190
....*....|....*....|....*....|....*...
gi 446512897 149 DEVTAVGDARFKEKCAQLFKERHKE--SSFLMVSHSLN 184
Cdd:cd03259 155 DEPLSALDAKLREELREELKELQRElgITTIYVTHDQE 192
|
|
| ABC_drug_resistance_like |
cd03264 |
ABC-type multidrug transport system, ATPase component; The biological function of this family ... |
2-202 |
1.44e-23 |
|
ABC-type multidrug transport system, ATPase component; The biological function of this family is not well characterized, but display ABC domains similar to members of ABCA subfamily. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213231 [Multi-domain] Cd Length: 211 Bit Score: 93.80 E-value: 1.44e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 2 IKIENLTKSYrtptGRHYVFKDLNIEIPSGKSvAFIGRNGAGKSTLLRMIGGIDRPDSGKIITN--KTISWPVGLAG--- 76
Cdd:cd03264 1 LQLENLTKRY----GKKRALDGVSLTLGPGMY-GLLGPNGAGKTTLMRILATLTPPSSGTIRIDgqDVLKQPQKLRRrig 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 77 ------GFQGSLTGRENVKFVARLYA-KQEELKEKIEFVEEFAELGKYFDMPIKTYSSGMRSRLGFGLSMAFKFDYYIVD 149
Cdd:cd03264 76 ylpqefGVYPNFTVREFLDYIAWLKGiPSKEVKARVDEVLELVNLGDRAKKKIGSLSGGMRRRVGIAQALVGDPSILIVD 155
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 446512897 150 EVTAVGDARFKEKCAQLFKERHKESSFLMVSHSLNSLKEFCDVAIVFKNSYII 202
Cdd:cd03264 156 EPTAGLDPEERIRFRNLLSELGEDRIVILSTHIVEDVESLCNQVAVLNKGKLV 208
|
|
| ABC_Class3 |
cd03229 |
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is ... |
2-198 |
3.36e-23 |
|
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is comprised of all BPD (Binding Protein Dependent) systems that are largely represented in archaea and eubacteria and are primarily involved in scavenging solutes from the environment. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213196 [Multi-domain] Cd Length: 178 Bit Score: 91.86 E-value: 3.36e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 2 IKIENLTKSYrtptGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKIitnktiswpvglaggfqgS 81
Cdd:cd03229 1 LELKNVSKRY----GQKTVLNDVSLNIEAGEIVALLGPSGSGKSTLLRCIAGLEEPDSGSI------------------L 58
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 82 LTGREnvkfVARLYAKQEELKEKIEFVeeFAELGKYFDMPIK---TY--SSGMRSRLGFGLSMAFKFDYYIVDEVTAVGD 156
Cdd:cd03229 59 IDGED----LTDLEDELPPLRRRIGMV--FQDFALFPHLTVLeniALglSGGQQQRVALARALAMDPDVLLLDEPTSALD 132
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 446512897 157 ARFKEKCAQLFKERHKES--SFLMVSHSLNSLKEFCDVAIVFKN 198
Cdd:cd03229 133 PITRREVRALLKSLQAQLgiTVVLVTHDLDEAARLADRVVVLRD 176
|
|
| ABC_NatA_sodium_exporter |
cd03266 |
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a ... |
1-195 |
8.61e-23 |
|
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of a single ATP-binding protein and a single integral membrane protein.
Pssm-ID: 213233 [Multi-domain] Cd Length: 218 Bit Score: 91.66 E-value: 8.61e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 1 MIKIENLTKSYRTPTGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKIITN--KTISWP------V 72
Cdd:cd03266 1 MITADALTKRFRDVKKTVQAVDGVSFTVKPGEVTGLLGPNGAGKTTTLRMLAGLLEPDAGFATVDgfDVVKEPaearrrL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 73 GLAGGFQG---SLTGRENVKFVARLYA-KQEELKEKIEFVEEFAELGKYFDMPIKTYSSGMRSRLGFGLSMAFKFDYYIV 148
Cdd:cd03266 81 GFVSDSTGlydRLTARENLEYFAGLYGlKGDELTARLEELADRLGMEELLDRRVGGFSTGMRQKVAIARALVHDPPVLLL 160
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 446512897 149 DEVTA----VGDARFKEKCAQLfkeRHKESSFLMVSHSLNSLKEFCDVAIV 195
Cdd:cd03266 161 DEPTTgldvMATRALREFIRQL---RALGKCILFSTHIMQEVERLCDRVVV 208
|
|
| ABC_MetN_methionine_transporter |
cd03258 |
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ... |
1-204 |
3.12e-22 |
|
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ABC-type transporter encoded by metN of the metNPQ operon in Bacillus subtilis that is involved in methionine transport. Other members of this system include the MetP permease and the MetQ substrate binding protein. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213225 [Multi-domain] Cd Length: 233 Bit Score: 90.72 E-value: 3.12e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 1 MIKIENLTKSYRTPTGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKIITNKTISwpVGLAGG--- 77
Cdd:cd03258 1 MIELKNVSKVFGDTGGKVTALKDVSLSVPKGEIFGIIGRSGAGKSTLIRCINGLERPTSGSVLVDGTDL--TLLSGKelr 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 78 ---------FQG-----SLTGRENVKF---VARLyaKQEELKEKIEFVEEFAELGKYFDMPIKTYSSGMRSRLGFGLSMA 140
Cdd:cd03258 79 karrrigmiFQHfnllsSRTVFENVALpleIAGV--PKAEIEERVLELLELVGLEDKADAYPAQLSGGQKQRVGIARALA 156
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446512897 141 FKFDYYIVDEVTAVGDARFKEKCAQLFKERHKES--SFLMVSHSLNSLKEFCDVAIVFKNSYIIGY 204
Cdd:cd03258 157 NNPKVLLCDEATSALDPETTQSILALLRDINRELglTIVLITHEMEVVKRICDRVAVMEKGEVVEE 222
|
|
| ABC_tran |
pfam00005 |
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ... |
21-153 |
5.60e-22 |
|
ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.
Pssm-ID: 394964 [Multi-domain] Cd Length: 150 Bit Score: 87.70 E-value: 5.60e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 21 FKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKI-------------ITNKTISWpVGLAGGFQGSLTGREN 87
Cdd:pfam00005 1 LKNVSLTLNPGEILALVGPNGAGKSTLLKLIAGLLSPTEGTIlldgqdltdderkSLRKEIGY-VFQDPQLFPRLTVREN 79
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446512897 88 VKFVARLYA-KQEELKEKIEFVEEFAELG----KYFDMPIKTYSSGMRSRLGFGLSMAFKFDYYIVDEVTA 153
Cdd:pfam00005 80 LRLGLLLKGlSKREKDARAEEALEKLGLGdladRPVGERPGTLSGGQRQRVAIARALLTKPKLLLLDEPTA 150
|
|
| LolD |
COG1136 |
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis]; |
1-94 |
5.70e-22 |
|
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440751 [Multi-domain] Cd Length: 227 Bit Score: 89.72 E-value: 5.70e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 1 MIKIENLTKSYRTPTGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKIIT---------------- 64
Cdd:COG1136 4 LLELRNLTKSYGTGEGEVTALRGVSLSIEAGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVLIdgqdisslserelarl 83
|
90 100 110
....*....|....*....|....*....|....*.
gi 446512897 65 -NKTISWpVglaggFQG-----SLTGRENVKFVARL 94
Cdd:COG1136 84 rRRHIGF-V-----FQFfnllpELTALENVALPLLL 113
|
|
| ABC_Metallic_Cations |
cd03235 |
ATP-binding cassette domain of the metal-type transporters; This family includes transporters ... |
3-198 |
8.26e-22 |
|
ATP-binding cassette domain of the metal-type transporters; This family includes transporters involved in the uptake of various metallic cations such as iron, manganese, and zinc. The ATPases of this group of transporters are very similar to members of iron-siderophore uptake family suggesting that they share a common ancestor. The best characterized metal-type ABC transporters are the YfeABCD system of Y. pestis, the SitABCD system of Salmonella enterica serovar Typhimurium, and the SitABCD transporter of Shigella flexneri. Moreover other uncharacterized homologs of these metal-type transporters are mainly found in pathogens like Haemophilus or enteroinvasive E. coli isolates.
Pssm-ID: 213202 [Multi-domain] Cd Length: 213 Bit Score: 89.13 E-value: 8.26e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 3 KIENLTKSYrtptGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKIITN-KTISWPVGLAG----- 76
Cdd:cd03235 1 EVEDLTVSY----GGHPVLEDVSFEVKPGEFLAIVGPNGAGKSTLLKAILGLLKPTSGSIRVFgKPLEKERKRIGyvpqr 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 77 -----GFQGS-----LTGRENVKFVARLYAKQEelKEKIEFVEEFAELGKYFDMPIKTYSSGMRSRLGFGLSMAFKFDYY 146
Cdd:cd03235 77 rsidrDFPISvrdvvLMGLYGHKGLFRRLSKAD--KAKVDEALERVGLSELADRQIGELSGGQQQRVLLARALVQDPDLL 154
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 446512897 147 IVDEVTAVGDARFKEKCAQLFKERHKES-SFLMVSHSLNSLKEFCDVAIVFKN 198
Cdd:cd03235 155 LLDEPFAGVDPKTQEDIYELLRELRREGmTILVVTHDLGLVLEYFDRVLLLNR 207
|
|
| ABC_MalK_N |
cd03301 |
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) ... |
2-181 |
2.48e-21 |
|
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) proteins function from bacteria to human, mediating the translocation of substances into and out of cells or organelles. ABC transporters contain two transmembrane-spanning domains (TMDs) or subunits and two nucleotide binding domains (NBDs) or subunits that couple transport to the hydrolysis of ATP. In the maltose transport system, the periplasmic maltose binding protein (MBP) stimulates the ATPase activity of the membrane-associated transporter, which consists of two transmembrane subunits, MalF and MalG, and two copies of the ATP binding subunit, MalK, and becomes tightly bound to the transporter in the catalytic transition state, ensuring that maltose is passed to the transporter as ATP is hydrolyzed.
Pssm-ID: 213268 [Multi-domain] Cd Length: 213 Bit Score: 87.70 E-value: 2.48e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 2 IKIENLTKSYrtptGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKII-----TNKTISWPVGLAG 76
Cdd:cd03301 1 VELENVTKRF----GNVTALDDLNLDIADGEFVVLLGPSGCGKTTTLRMIAGLEEPTSGRIYiggrdVTDLPPKDRDIAM 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 77 GFQG-----SLTGRENVKFVARL-YAKQEELKEKIEFVEEFAELGKYFDMPIKTYSSGMRSRLGFGLSMAFKFDYYIVDE 150
Cdd:cd03301 77 VFQNyalypHMTVYDNIAFGLKLrKVPKDEIDERVREVAELLQIEHLLDRKPKQLSGGQRQRVALGRAIVREPKVFLMDE 156
|
170 180 190
....*....|....*....|....*....|...
gi 446512897 151 VTAVGDARFKEKCAQLFKERHKE--SSFLMVSH 181
Cdd:cd03301 157 PLSNLDAKLRVQMRAELKRLQQRlgTTTIYVTH 189
|
|
| ABC_PstB_phosphate_transporter |
cd03260 |
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of ... |
2-183 |
2.48e-21 |
|
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of fundamental importance in the cell physiology of bacteria because phosphate is required as a nutrient. The Pst system of E. coli comprises four distinct subunits encoded by the pstS, pstA, pstB, and pstC genes. The PstS protein is a phosphate-binding protein located in the periplasmic space. PstA and PstC are hydrophobic and they form the transmembrane portion of the Pst system. PstB is the catalytic subunit, which couples the energy of ATP hydrolysis to the import of phosphate across cellular membranes through the Pst system, often referred as ABC-protein. PstB belongs to one of the largest superfamilies of proteins characterized by a highly conserved adenosine triphosphate (ATP) binding cassette (ABC), which is also a nucleotide binding domain (NBD).
Pssm-ID: 213227 [Multi-domain] Cd Length: 227 Bit Score: 88.01 E-value: 2.48e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 2 IKIENLTKSYrtptGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGI-----DRPDSGKII--------TNKTI 68
Cdd:cd03260 1 IELRDLNVYY----GDKHALKDISLDIPKGEITALIGPSGCGKSTLLRLLNRLndlipGAPDEGEVLldgkdiydLDVDV 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 69 SWP---VGLAggFQ------GSLtgRENVKFVARL--YAKQEELKEKIEFVEEFAELGKYFDMPIKTY--SSGMRSRLGF 135
Cdd:cd03260 77 LELrrrVGMV--FQkpnpfpGSI--YDNVAYGLRLhgIKLKEELDERVEEALRKAALWDEVKDRLHALglSGGQQQRLCL 152
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 446512897 136 GLSMAFKFDYYIVDEVTAVGDARFKEKCAQLFKERHKESSFLMVSHSL 183
Cdd:cd03260 153 ARALANEPEVLLLDEPTSALDPISTAKIEELIAELKKEYTIVIVTHNM 200
|
|
| ABCC_MRP_Like |
cd03228 |
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP ... |
2-198 |
1.32e-20 |
|
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP (Multidrug Resistance Protein)-like transporters are involved in drug, peptide, and lipid export. They belong to the subfamily C of the ATP-binding cassette (ABC) superfamily of transport proteins. The ABCC subfamily contains transporters with a diverse functional spectrum that includes ion transport, cell surface receptor, and toxin secretion activities. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains, each composed of six transmembrane (TM) helices, and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213195 [Multi-domain] Cd Length: 171 Bit Score: 84.74 E-value: 1.32e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 2 IKIENLTKSYrtPTGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKIITNKTiswpvglaggfqgs 81
Cdd:cd03228 1 IEFKNVSFSY--PGRPKPVLKDVSLTIKPGEKVAIVGPSGSGKSTLLKLLLRLYDPTSGEILIDGV-------------- 64
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 82 ltgreNVKFVARlyakqEELKEKIEFVEEFAELgkyFDMPIKT--YSSGMRSRLgfGLSMAF--KFDYYIVDEVTAVGDA 157
Cdd:cd03228 65 -----DLRDLDL-----ESLRKNIAYVPQDPFL---FSGTIREniLSGGQRQRI--AIARALlrDPPILILDEATSALDP 129
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 446512897 158 RFKEKCAQLFKERHKESSFLMVSHSLNSLKeFCDVAIVFKN 198
Cdd:cd03228 130 ETEALILEALRALAKGKTVIVIAHRLSTIR-DADRIIVLDD 169
|
|
| AbcC |
COG1135 |
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism]; |
1-63 |
2.61e-20 |
|
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 440750 [Multi-domain] Cd Length: 339 Bit Score: 87.44 E-value: 2.61e-20
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446512897 1 MIKIENLTKSYRTPTGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKII 63
Cdd:COG1135 1 MIELENLSKTFPTKGGPVTALDDVSLTIEKGEIFGIIGYSGAGKSTLIRCINLLERPTSGSVL 63
|
|
| ABC_Iron-Siderophores_B12_Hemin |
cd03214 |
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related ... |
3-198 |
3.77e-20 |
|
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; ABC transporters, involved in the uptake of siderophores, heme, and vitamin B12, are widely conserved in bacteria and archaea. Only very few species lack representatives of the siderophore family transporters. The E. coli BtuCD protein is an ABC transporter mediating vitamin B12 uptake. The two ATP-binding cassettes (BtuD) are in close contact with each other, as are the two membrane-spanning subunits (BtuC); this arrangement is distinct from that observed for the E. coli lipid flippase MsbA. The BtuC subunits provide 20 transmembrane helices grouped around a translocation pathway that is closed to the cytoplasm by a gate region, whereas the dimer arrangement of the BtuD subunits resembles the ATP-bound form of the Rad50 DNA repair enzyme. A prominent cytoplasmic loop of BtuC forms the contact region with the ATP-binding cassette and represent a conserved motif among the ABC transporters.
Pssm-ID: 213181 [Multi-domain] Cd Length: 180 Bit Score: 83.64 E-value: 3.77e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 3 KIENLTKSYrtptGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKI-ITNKTISwpvglaggfqgS 81
Cdd:cd03214 1 EVENLSVGY----GGRTVLDDLSLSIEAGEIVGILGPNGAGKSTLLKTLAGLLKPSSGEIlLDGKDLA-----------S 65
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 82 LTGRENVKFVArlYAKQ--EELKekiefVEEFAElgKYFDmpikTYSSGMRSRLGFGLSMAFKFDYYIVDEVTAVGDARF 159
Cdd:cd03214 66 LSPKELARKIA--YVPQalELLG-----LAHLAD--RPFN----ELSGGERQRVLLARALAQEPPILLLDEPTSHLDIAH 132
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 446512897 160 KEKCAQLFKERHKESSF--LMVSHSLNSLKEFCDVAIVFKN 198
Cdd:cd03214 133 QIELLELLRRLARERGKtvVMVLHDLNLAARYADRVILLKD 173
|
|
| ZnuC |
COG1121 |
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism]; ... |
1-191 |
5.31e-20 |
|
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440738 [Multi-domain] Cd Length: 245 Bit Score: 84.76 E-value: 5.31e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 1 MIKIENLTKSYrtptGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKI-ITNKTISWPVGLAG--- 76
Cdd:COG1121 6 AIELENLTVSY----GGRPVLEDVSLTIPPGEFVAIVGPNGAGKSTLLKAILGLLPPTSGTVrLFGKPPRRARRRIGyvp 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 77 -------GFQgsLTGREnvkFVA----------RLYAKQEelKEKIEFVEEFAELGKYFDMPIKTYSSGMRSRLGFGLSM 139
Cdd:COG1121 82 qraevdwDFP--ITVRD---VVLmgrygrrglfRRPSRAD--REAVDEALERVGLEDLADRPIGELSGGQQQRVLLARAL 154
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 446512897 140 AFKFDYYIVDE-VTAVgDARFKEKCAQLFKERHKES-SFLMVSHSLNSLKEFCD 191
Cdd:COG1121 155 AQDPDLLLLDEpFAGV-DAATEEALYELLRELRREGkTILVVTHDLGAVREYFD 207
|
|
| ABC_OpuCA_Osmoprotection |
cd03295 |
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding ... |
2-184 |
5.98e-20 |
|
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing in a hyperosmolar environment. ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition, to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213262 [Multi-domain] Cd Length: 242 Bit Score: 84.66 E-value: 5.98e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 2 IKIENLTKSYRtptGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKIITN--KTISW-PVGL---- 74
Cdd:cd03295 1 IEFENVTKRYG---GGKKAVNNLNLEIAKGEFLVLIGPSGSGKTTTMKMINRLIEPTSGEIFIDgeDIREQdPVELrrki 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 75 ------AGGFQgSLTGRENVKFVARLyakQEELKEKIEfvEEFAELGKYFDMPIKTY--------SSGMRSRLGFGLSMA 140
Cdd:cd03295 78 gyviqqIGLFP-HMTVEENIALVPKL---LKWPKEKIR--ERADELLALVGLDPAEFadryphelSGGQQQRVGVARALA 151
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 446512897 141 FKFDYYIVDEVTAVGDARFKEKCAQLFKERHKES--SFLMVSHSLN 184
Cdd:cd03295 152 ADPPLLLMDEPFGALDPITRDQLQEEFKRLQQELgkTIVFVTHDID 197
|
|
| ABC_Carb_Monos_I |
cd03216 |
First domain of the ATP-binding cassette component of monosaccharide transport system; This ... |
2-203 |
8.65e-20 |
|
First domain of the ATP-binding cassette component of monosaccharide transport system; This family represents the domain I of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. Pentoses include xylose, arabinose, and ribose. Important hexoses include glucose, galactose, and fructose. In members of the Carb_monos family, the single hydrophobic gene product forms a homodimer while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.
Pssm-ID: 213183 [Multi-domain] Cd Length: 163 Bit Score: 82.48 E-value: 8.65e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 2 IKIENLTKSYrtptGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKIITNktiswpvglaggfqgs 81
Cdd:cd03216 1 LELRGITKRF----GGVKALDGVSLSVRRGEVHALLGENGAGKSTLMKILSGLYKPDSGEILVD---------------- 60
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 82 ltGREnVKFVARlyakQEELKEKIEFVeefaelgkyFDMPIktyssGMRSRLGFGLSMAFKFDYYIVDEVTAVGDARFKE 161
Cdd:cd03216 61 --GKE-VSFASP----RDARRAGIAMV---------YQLSV-----GERQMVEIARALARNARLLILDEPTAALTPAEVE 119
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 446512897 162 kcaQLFK--ERHKES--SFLMVSHSLNSLKEFCDVAIVFKNSYIIG 203
Cdd:cd03216 120 ---RLFKviRRLRAQgvAVIFISHRLDEVFEIADRVTVLRDGRVVG 162
|
|
| SunT |
COG2274 |
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase ... |
2-202 |
1.40e-19 |
|
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms];
Pssm-ID: 441875 [Multi-domain] Cd Length: 711 Bit Score: 86.43 E-value: 1.40e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 2 IKIENLTKSYrtPTGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKIITN----KTISwPVGLAG- 76
Cdd:COG2274 474 IELENVSFRY--PGDSPPVLDNISLTIKPGERVAIVGRSGSGKSTLLKLLLGLYEPTSGRILIDgidlRQID-PASLRRq 550
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 77 -G--------FQGSLtgRENVKFvARLYAKQEELKE--KI----EFVEEFAeLGkyFDMPI----KTYSSGMRSRLGFGL 137
Cdd:COG2274 551 iGvvlqdvflFSGTI--RENITL-GDPDATDEEIIEaaRLaglhDFIEALP-MG--YDTVVgeggSNLSGGQRQRLAIAR 624
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446512897 138 SMAFKFDYYIVDEVTAVGDARFKEKCAQLFKERHKESSFLMVSHSLNSLKEfCDVAIVFKNSYII 202
Cdd:COG2274 625 ALLRNPRILILDEATSALDAETEAIILENLRRLLKGRTVIIIAHRLSTIRL-ADRIIVLDKGRIV 688
|
|
| CeuD |
COG4604 |
ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and ... |
1-62 |
1.55e-19 |
|
ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443654 [Multi-domain] Cd Length: 252 Bit Score: 83.98 E-value: 1.55e-19
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446512897 1 MIKIENLTKSYrtptGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKI 62
Cdd:COG4604 1 MIEIKNVSKRY----GGKVVLDDVSLTIPKGGITALIGPNGAGKSTLLSMISRLLPPDSGEV 58
|
|
| ABC_NatA_like |
cd03267 |
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; ... |
2-195 |
2.46e-19 |
|
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled to proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of the single ATP-binding protein and the single integral membrane protein.
Pssm-ID: 213234 [Multi-domain] Cd Length: 236 Bit Score: 83.15 E-value: 2.46e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 2 IKIENLTKSYRTPTG-------------RHY----VFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKIIT 64
Cdd:cd03267 1 IEVSNLSKSYRVYSKepgligslkslfkRKYreveALKGISFTIEKGEIVGFIGPNGAGKTTTLKILSGLLQPTSGEVRV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 65 NKTISWP--------VGLAGGfQGS-----LTGRENVKFVARLYA-KQEELKEKIEFVEEFAELGKYFDMPIKTYSSGMR 130
Cdd:cd03267 81 AGLVPWKrrkkflrrIGVVFG-QKTqlwwdLPVIDSFYLLAAIYDlPPARFKKRLDELSELLDLEELLDTPVRQLSLGQR 159
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446512897 131 SRLGFGLSMAFKFDYYIVDEVTAVGDARFKEKCAQLFKE--RHKESSFLMVSHSLNSLKEFCDVAIV 195
Cdd:cd03267 160 MRAEIAAALLHEPEILFLDEPTIGLDVVAQENIRNFLKEynRERGTTVLLTSHYMKDIEALARRVLV 226
|
|
| YhaQ |
COG4152 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
1-197 |
3.64e-19 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 443322 [Multi-domain] Cd Length: 298 Bit Score: 83.62 E-value: 3.64e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 1 MIKIENLTKSYrtptGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGkiitnkTISW---PVGLA-- 75
Cdd:COG4152 1 MLELKGLTKRF----GDKTAVDDVSFTVPKGEIFGLLGPNGAGKTTTIRIILGILAPDSG------EVLWdgePLDPEdr 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 76 ----------GGFQgSLTGRENVKFVARL--YAKQEELKEKIEFVEEFaELGKYFDMPIKTYSSGMRSRLGFGLSMAFKF 143
Cdd:COG4152 71 rrigylpeerGLYP-KMKVGEQLVYLARLkgLSKAEAKRRADEWLERL-GLGDRANKKVEELSKGNQQKVQLIAALLHDP 148
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446512897 144 DYYIVDE-------VTAvgdarfkEKCAQLFKERHKE-SSFLMVSHSLNSLKEFCD-VAIVFK 197
Cdd:COG4152 149 ELLILDEpfsgldpVNV-------ELLKDVIRELAAKgTTVIFSSHQMELVEELCDrIVIINK 204
|
|
| GsiA |
COG1123 |
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ... |
1-198 |
5.98e-19 |
|
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440740 [Multi-domain] Cd Length: 514 Bit Score: 84.57 E-value: 5.98e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 1 MIKIENLTKSYRT-PTGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKI-ITNKTISwpvGLAGG- 77
Cdd:COG1123 260 LLEVRNLSKRYPVrGKGGVRAVDDVSLTLRRGETLGLVGESGSGKSTLARLLLGLLRPTSGSIlFDGKDLT---KLSRRs 336
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 78 -----------FQ---GSL----TGRENVKFVARLY--AKQEELKEKIEFVEEFAELG-KYFDMPIKTYSSGMRSRLGFG 136
Cdd:COG1123 337 lrelrrrvqmvFQdpySSLnprmTVGDIIAEPLRLHglLSRAERRERVAELLERVGLPpDLADRYPHELSGGQRQRVAIA 416
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446512897 137 LSMAFKFDYYIVDEVTAVGDARFKEKCAQLFKERHKES--SFLMVSHSLNSLKEFCDVAIVFKN 198
Cdd:COG1123 417 RALALEPKLLILDEPTSALDVSVQAQILNLLRDLQRELglTYLFISHDLAVVRYIADRVAVMYD 480
|
|
| ABCF_EF-3 |
cd03221 |
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is ... |
2-198 |
1.12e-18 |
|
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is a cytosolic protein required by fungal ribosomes for in vitro protein synthesis and for in vivo growth. EF-3 stimulates the binding of the EF-1: GTP: aa-tRNA ternary complex to the ribosomal A site by facilitated release of the deacylated tRNA from the E site. The reaction requires ATP hydrolysis. EF-3 contains two ATP nucleotide binding sequence (NBS) motifs. NBSI is sufficient for the intrinsic ATPase activity. NBSII is essential for the ribosome-stimulated functions.
Pssm-ID: 213188 [Multi-domain] Cd Length: 144 Bit Score: 79.03 E-value: 1.12e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 2 IKIENLTKSYrtptGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKIITNKTIswpvglaggfqgs 81
Cdd:cd03221 1 IELENLSKTY----GGKLLLKDISLTINPGDRIGLVGRNGAGKSTLLKLIAGELEPDEGIVTWGSTV------------- 63
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 82 ltgrenvkfvarlyakqeelkeKIEFVEEFaelgkyfdmpiktySSGMRSRLGFGLSMAFKFDYYIVDEVTAVGDARFKE 161
Cdd:cd03221 64 ----------------------KIGYFEQL--------------SGGEKMRLALAKLLLENPNLLLLDEPTNHLDLESIE 107
|
170 180 190
....*....|....*....|....*....|....*..
gi 446512897 162 KCAQLFKErhKESSFLMVSHSLNSLKEFCDVAIVFKN 198
Cdd:cd03221 108 ALEEALKE--YPGTVILVSHDRYFLDQVATKIIELED 142
|
|
| MalK |
COG3839 |
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism]; ... |
1-114 |
1.64e-18 |
|
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism];
Pssm-ID: 443050 [Multi-domain] Cd Length: 352 Bit Score: 82.43 E-value: 1.64e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 1 MIKIENLTKSYrtptGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKI-ITNKTISW-PV---GLA 75
Cdd:COG3839 3 SLELENVSKSY----GGVEALKDIDLDIEDGEFLVLLGPSGCGKSTLLRMIAGLEDPTSGEIlIGGRDVTDlPPkdrNIA 78
|
90 100 110 120
....*....|....*....|....*....|....*....|....*..
gi 446512897 76 GGFQG-----SLTGRENVKF---VARLyaKQEELKEKiefVEEFAEL 114
Cdd:COG3839 79 MVFQSyalypHMTVYENIAFplkLRKV--PKAEIDRR---VREAAEL 120
|
|
| FepC |
COG1120 |
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion ... |
1-198 |
1.69e-18 |
|
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion transport and metabolism, Coenzyme transport and metabolism];
Pssm-ID: 440737 [Multi-domain] Cd Length: 254 Bit Score: 81.24 E-value: 1.69e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 1 MIKIENLTKSYrtptGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKI------ITN-------KT 67
Cdd:COG1120 1 MLEAENLSVGY----GGRPVLDDVSLSLPPGEVTALLGPNGSGKSTLLRALAGLLKPSSGEVlldgrdLASlsrrelaRR 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 68 ISW-PVGLAGGFqgSLTGRENVK-----FVARLYAKQEELKEKIEFVEEFAELGKYFDMPIKTYSSGMRSRLGFGLSMAF 141
Cdd:COG1120 77 IAYvPQEPPAPF--GLTVRELVAlgrypHLGLFGRPSAEDREAVEEALERTGLEHLADRPVDELSGGERQRVLIARALAQ 154
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 446512897 142 KFDYYIVDEVTAVGDARFKEKCAQLFKERHKES--SFLMVSHSLNSLKEFCDVAIVFKN 198
Cdd:COG1120 155 EPPLLLLDEPTSHLDLAHQLEVLELLRRLARERgrTVVMVLHDLNLAARYADRLVLLKD 213
|
|
| metN |
PRK11153 |
DL-methionine transporter ATP-binding subunit; Provisional |
1-65 |
4.92e-18 |
|
DL-methionine transporter ATP-binding subunit; Provisional
Pssm-ID: 236863 [Multi-domain] Cd Length: 343 Bit Score: 81.00 E-value: 4.92e-18
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446512897 1 MIKIENLTKSYRTPTGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKIITN 65
Cdd:PRK11153 1 MIELKNISKVFPQGGRTIHALNNVSLHIPAGEIFGVIGASGAGKSTLIRCINLLERPTSGRVLVD 65
|
|
| Uup |
COG0488 |
ATPase components of ABC transporters with duplicated ATPase domains [General function ... |
4-133 |
7.06e-18 |
|
ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];
Pssm-ID: 440254 [Multi-domain] Cd Length: 520 Bit Score: 81.65 E-value: 7.06e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 4 IENLTKSYrtptGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKIITNKTISwpVG-LA--GGFQG 80
Cdd:COG0488 1 LENLSKSF----GGRPLLDDVSLSINPGDRIGLVGRNGAGKSTLLKILAGELEPDSGEVSIPKGLR--IGyLPqePPLDD 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 81 SLTGRENV----KFVARLYAKQEELKEKIEFV-----------EEFAELGKY-------------------FDMPIKTYS 126
Cdd:COG0488 75 DLTVLDTVldgdAELRALEAELEELEAKLAEPdedlerlaelqEEFEALGGWeaearaeeilsglgfpeedLDRPVSELS 154
|
....*..
gi 446512897 127 SGMRSRL 133
Cdd:COG0488 155 GGWRRRV 161
|
|
| cbiO |
PRK13647 |
cobalt transporter ATP-binding subunit; Provisional |
2-204 |
2.03e-17 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237457 [Multi-domain] Cd Length: 274 Bit Score: 78.62 E-value: 2.03e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 2 IKIENLTksYRTPTGRHyVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKI------ITNKTISW---PV 72
Cdd:PRK13647 5 IEVEDLH--FRYKDGTK-ALKGLSLSIPEGSKTALLGPNGAGKSTLLLHLNGIYLPQRGRVkvmgreVNAENEKWvrsKV 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 73 GLAggFQG------SLTGRENVKFVAR-LYAKQEELKEKIEFVEEFAELGKYFDMPIKTYSSGMRSRLGFGLSMAFKFDY 145
Cdd:PRK13647 82 GLV--FQDpddqvfSSTVWDDVAFGPVnMGLDKDEVERRVEEALKAVRMWDFRDKPPYHLSYGQKKRVAIAGVLAMDPDV 159
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 146 YIVDEVTAVGDARFKEKCAQLFKERHKESSFLMVS-HSLNSLKEFCDVAIVFKNSYIIGY 204
Cdd:PRK13647 160 IVLDEPMAYLDPRGQETLMEILDRLHNQGKTVIVAtHDVDLAAEWADQVIVLKEGRVLAE 219
|
|
| PotA |
COG3842 |
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport ... |
1-63 |
4.43e-17 |
|
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443052 [Multi-domain] Cd Length: 353 Bit Score: 78.60 E-value: 4.43e-17
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446512897 1 MIKIENLTKSYrtptGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKII 63
Cdd:COG3842 5 ALELENVSKRY----GDVTALDDVSLSIEPGEFVALLGPSGCGKTTLLRMIAGFETPDSGRIL 63
|
|
| ABC_CysA_sulfate_importer |
cd03296 |
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex ... |
2-181 |
5.71e-17 |
|
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex cysAWTP involved in sulfate import. Responsible for energy coupling to the transport system. The complex is composed of two ATP-binding proteins (cysA), two transmembrane proteins (cysT and cysW), and a solute-binding protein (cysP). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213263 [Multi-domain] Cd Length: 239 Bit Score: 76.61 E-value: 5.71e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 2 IKIENLTKSYrtptGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKII------TNKTI-SWPVGL 74
Cdd:cd03296 3 IEVRNVSKRF----GDFVALDDVSLDIPSGELVALLGPSGSGKTTLLRLIAGLERPDSGTILfggedaTDVPVqERNVGF 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 75 AggFQG-----SLTGRENVKFVARLYAKQE-----ELKEKIEFVEEFAELGKYFDMPIKTYSSGMRSRLGFGLSMAFKFD 144
Cdd:cd03296 79 V--FQHyalfrHMTVFDNVAFGLRVKPRSErppeaEIRAKVHELLKLVQLDWLADRYPAQLSGGQRQRVALARALAVEPK 156
|
170 180 190
....*....|....*....|....*....|....*....
gi 446512897 145 YYIVDEVTAVGDARFKEKCAQLFKERHKESSF--LMVSH 181
Cdd:cd03296 157 VLLLDEPFGALDAKVRKELRRWLRRLHDELHVttVFVTH 195
|
|
| FtsE |
COG2884 |
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning]; |
1-63 |
6.00e-17 |
|
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442130 [Multi-domain] Cd Length: 223 Bit Score: 76.24 E-value: 6.00e-17
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446512897 1 MIKIENLTKSYRtptGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKII 63
Cdd:COG2884 1 MIRFENVSKRYP---GGREALSDVSLEIEKGEFVFLTGPSGAGKSTLLKLLYGEERPTSGQVL 60
|
|
| Uup |
COG0488 |
ATPase components of ABC transporters with duplicated ATPase domains [General function ... |
1-69 |
7.30e-17 |
|
ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];
Pssm-ID: 440254 [Multi-domain] Cd Length: 520 Bit Score: 78.57 E-value: 7.30e-17
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446512897 1 MIKIENLTKSYrtptGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKIITNKTIS 69
Cdd:COG0488 315 VLELEGLSKSY----GDKTLLDDLSLRIDRGDRIGLIGPNGAGKSTLLKLLAGELEPDSGTVKLGETVK 379
|
|
| GsiA |
COG1123 |
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ... |
1-202 |
7.38e-17 |
|
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440740 [Multi-domain] Cd Length: 514 Bit Score: 78.41 E-value: 7.38e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 1 MIKIENLTKSYrtPTGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPD---SGKIITNKT--ISWPVGLA 75
Cdd:COG1123 4 LLEVRDLSVRY--PGGDVPAVDGVSLTIAPGETVALVGESGSGKSTLALALMGLLPHGgriSGEVLLDGRdlLELSEALR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 76 GG-----FQG------SLTGRENVKFVARLY-AKQEELKEKIEFVEEFAELGKYFDMPIKTYSSGMRSRLGFGLSMAFKF 143
Cdd:COG1123 82 GRrigmvFQDpmtqlnPVTVGDQIAEALENLgLSRAEARARVLELLEAVGLERRLDRYPHQLSGGQRQRVAIAMALALDP 161
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446512897 144 DYYIVDEVTAVGDARFKEKCAQLFKERHKES--SFLMVSHSLNSLKEFCDVAIVFKNSYII 202
Cdd:COG1123 162 DLLIADEPTTALDVTTQAEILDLLRELQRERgtTVLLITHDLGVVAEIADRVVVMDDGRIV 222
|
|
| ABCC_Glucan_exporter_like |
cd03254 |
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan ... |
2-202 |
8.16e-17 |
|
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan exporter ATP-binding protein. In A. tumefaciens cyclic beta-1, 2-glucan must be transported into the periplasmic space to exert its action as a virulence factor. This subfamily belongs to the MRP-like family and is involved in drug, peptide, and lipid export. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains each composed of six transmembrane (TM) helices and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213221 [Multi-domain] Cd Length: 229 Bit Score: 76.11 E-value: 8.16e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 2 IKIENLTKSYRtptGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKI---------ITNKTISWPV 72
Cdd:cd03254 3 IEFENVNFSYD---EKKPVLKDINFSIKPGETVAIVGPTGAGKTTLINLLMRFYDPQKGQIlidgidirdISRKSLRSMI 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 73 GL----AGGFQGSLtgRENVKFvARLYAKQEELKEKI------EFVE--------EFAELGKYFdmpiktySSGMRSRLG 134
Cdd:cd03254 80 GVvlqdTFLFSGTI--MENIRL-GRPNATDEEVIEAAkeagahDFIMklpngydtVLGENGGNL-------SQGERQLLA 149
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446512897 135 FGLSMAFKFDYYIVDEVTAVGD----ARFKEKCAQLFKERhkesSFLMVSHSLNSLKeFCDVAIVFKNSYII 202
Cdd:cd03254 150 IARAMLRDPKILILDEATSNIDteteKLIQEALEKLMKGR----TSIIIAHRLSTIK-NADKILVLDDGKII 216
|
|
| cbiO |
PRK13632 |
cobalt transporter ATP-binding subunit; Provisional |
1-202 |
9.75e-17 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237452 [Multi-domain] Cd Length: 271 Bit Score: 76.57 E-value: 9.75e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 1 MIKIENLTKSYrtPTGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKI-ITNKTISWP-------- 71
Cdd:PRK13632 7 MIKVENVSFSY--PNSENNALKNVSFEINEGEYVAILGHNGSGKSTISKILTGLLKPQSGEIkIDGITISKEnlkeirkk 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 72 VGLAggFQ-------GSLT------GRENVKFvarlyaKQEELKEKIEFVEEFAELGKYFDMPIKTYSSGMRSRLGFGLS 138
Cdd:PRK13632 85 IGII--FQnpdnqfiGATVeddiafGLENKKV------PPKKMKDIIDDLAKKVGMEDYLDKEPQNLSGGQKQRVAIASV 156
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446512897 139 MAFKFDYYIVDEVTAVGDARFKEKCAQLFKERHKESSFLMVS--HSLNSLKEfCDVAIVFKNSYII 202
Cdd:PRK13632 157 LALNPEIIIFDESTSMLDPKGKREIKKIMVDLRKTRKKTLISitHDMDEAIL-ADKVIVFSEGKLI 221
|
|
| ABC_PhnC_transporter |
cd03256 |
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; ... |
2-202 |
9.77e-17 |
|
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Phosphonates are a class of organophosphorus compounds characterized by a chemically stable carbon-to-phosphorus (C-P) bond. Phosphonates are widespread among naturally occurring compounds in all kingdoms of wildlife, but only prokaryotic microorganisms are able to cleave this bond. Certain bacteria such as E. coli can use alkylphosphonates as a phosphorus source. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213223 [Multi-domain] Cd Length: 241 Bit Score: 76.07 E-value: 9.77e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 2 IKIENLTKSYrtPTGRHyVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKIITNKTiswPVGLAGG---- 77
Cdd:cd03256 1 IEVENLSKTY--PNGKK-ALKDVSLSINPGEFVALIGPSGAGKSTLLRCLNGLVEPTSGSVLIDGT---DINKLKGkalr 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 78 ---------FQG-SLTGR----ENV-----------KFVARLYAKqEELKEKIEFVEEFAELGKYFDMpIKTYSSGMRSR 132
Cdd:cd03256 75 qlrrqigmiFQQfNLIERlsvlENVlsgrlgrrstwRSLFGLFPK-EEKQRALAALERVGLLDKAYQR-ADQLSGGQQQR 152
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446512897 133 LGFGLSMAFKFDYYIVDEVTAVGDARFKEKCAQLFKE--RHKESSFLMVSHSLNSLKEFCDVAIVFKNSYII 202
Cdd:cd03256 153 VAIARALMQQPKLILADEPVASLDPASSRQVMDLLKRinREEGITVIVSLHQVDLAREYADRIVGLKDGRIV 224
|
|
| YbbA |
COG4181 |
Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase ... |
1-62 |
1.05e-16 |
|
Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 443338 [Multi-domain] Cd Length: 233 Bit Score: 75.93 E-value: 1.05e-16
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446512897 1 MIKIENLTKSYRTPTGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKI 62
Cdd:COG4181 8 IIELRGLTKTVGTGAGELTILKGISLEVEAGESVAIVGASGSGKSTLLGLLAGLDRPTSGTV 69
|
|
| LivG |
COG0411 |
ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid ... |
1-195 |
1.47e-16 |
|
ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid transport and metabolism];
Pssm-ID: 440180 [Multi-domain] Cd Length: 257 Bit Score: 75.85 E-value: 1.47e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 1 MIKIENLTKSYRtptGRHYVfKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKI------ITNktisWPV-- 72
Cdd:COG0411 4 LLEVRGLTKRFG---GLVAV-DDVSLEVERGEIVGLIGPNGAGKTTLFNLITGFYRPTSGRIlfdgrdITG----LPPhr 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 73 ----GLAGGFQ-----GSLTGRENVKfVARL----------------YAKQE-ELKEKIEFVEEFAELGKYFDMPIKTYS 126
Cdd:COG0411 76 iarlGIARTFQnprlfPELTVLENVL-VAAHarlgrgllaallrlprARREErEARERAEELLERVGLADRADEPAGNLS 154
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446512897 127 SGMRSRLGFGLSMAFKFDYYIVDEVTA-VGDARfKEKCAQLFKERHKES--SFLMVSHSLNSLKEFCDVAIV 195
Cdd:COG0411 155 YGQQRRLEIARALATEPKLLLLDEPAAgLNPEE-TEELAELIRRLRDERgiTILLIEHDMDLVMGLADRIVV 225
|
|
| CydD |
COG4988 |
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease ... |
2-202 |
2.08e-16 |
|
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444012 [Multi-domain] Cd Length: 563 Bit Score: 77.11 E-value: 2.08e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 2 IKIENLTKSYrtpTGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKIITN-------------KTI 68
Cdd:COG4988 337 IELEDVSFSY---PGGRPALDGLSLTIPPGERVALVGPSGAGKSTLLNLLLGFLPPYSGSILINgvdlsdldpaswrRQI 413
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 69 SWpVG----LaggFQGSLtgRENVKFvARLYAKQEELKEKIE--FVEEFaelgkyfdmpIKTYSSGMRSRL---GFGLSM 139
Cdd:COG4988 414 AW-VPqnpyL---FAGTI--RENLRL-GRPDASDEELEAALEaaGLDEF----------VAALPDGLDTPLgegGRGLSG 476
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446512897 140 ----------AFKFDY--YIVDEVTA----VGDARFKEKCAQLFKERhkesSFLMVSHSLNSLKEfCDVAIVFKNSYII 202
Cdd:COG4988 477 gqaqrlalarALLRDAplLLLDEPTAhldaETEAEILQALRRLAKGR----TVILITHRLALLAQ-ADRILVLDDGRIV 550
|
|
| PRK13539 |
PRK13539 |
cytochrome c biogenesis protein CcmA; Provisional |
1-170 |
2.35e-16 |
|
cytochrome c biogenesis protein CcmA; Provisional
Pssm-ID: 237421 [Multi-domain] Cd Length: 207 Bit Score: 74.53 E-value: 2.35e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 1 MIKIENLTkSYRtptGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKIITNK---TISWP------ 71
Cdd:PRK13539 2 MLEGEDLA-CVR---GGRVLFSGLSFTLAAGEALVLTGPNGSGKTTLLRLIAGLLPPAAGTIKLDGgdiDDPDVaeachy 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 72 VGLAGGFQGSLTGRENVKFVARLY-AKQEELKEKIEFVeefaELGKYFDMPIKTYSSGMRSRLGFGLSMAFKFDYYIVDE 150
Cdd:PRK13539 78 LGHRNAMKPALTVAENLEFWAAFLgGEELDIAAALEAV----GLAPLAHLPFGYLSAGQKRRVALARLLVSNRPIWILDE 153
|
170 180
....*....|....*....|
gi 446512897 151 VTAVGDARFKEKCAQLFKER 170
Cdd:PRK13539 154 PTAALDAAAVALFAELIRAH 173
|
|
| ABC_ModC_like |
cd03299 |
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely ... |
2-202 |
5.63e-16 |
|
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely related to ModC. ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213266 [Multi-domain] Cd Length: 235 Bit Score: 73.91 E-value: 5.63e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 2 IKIENLTKSYRtptgrHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKIITNKTISWPV-----GLAG 76
Cdd:cd03299 1 LKVENLSKDWK-----EFKLKNVSLEVERGDYFVILGPTGSGKSVLLETIAGFIKPDSGKILLNGKDITNLppekrDISY 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 77 GFQG-----SLTGRENVKFVARL-YAKQEELKEKIEFVEEFAELGKYFDMPIKTYSSGMRSRLGFGLSMAFKFDYYIVDE 150
Cdd:cd03299 76 VPQNyalfpHMTVYKNIAYGLKKrKVDKKEIERKVLEIAEMLGIDHLLNRKPETLSGGEQQRVAIARALVVNPKILLLDE 155
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 446512897 151 VTAVGDARFKEKCAQLFKERHKESSF--LMVSHSLNSLKEFCDVAIVFKNSYII 202
Cdd:cd03299 156 PFSALDVRTKEKLREELKKIRKEFGVtvLHVTHDFEEAWALADKVAIMLNGKLI 209
|
|
| ABC_ModC_molybdenum_transporter |
cd03297 |
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type ... |
16-204 |
5.71e-16 |
|
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213264 [Multi-domain] Cd Length: 214 Bit Score: 73.48 E-value: 5.71e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 16 GRHYVFK-DLNIEIPSGKsVAFIGRNGAGKSTLLRMIGGIDRPDSGKII--------TNKTISWP-----VGLAggFQGS 81
Cdd:cd03297 8 KRLPDFTlKIDFDLNEEV-TGIFGASGAGKSTLLRCIAGLEKPDGGTIVlngtvlfdSRKKINLPpqqrkIGLV--FQQY 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 82 -----LTGRENVKFVARLYAKQEELKEKIEFVEEFAeLGKYFDMPIKTYSSGMRSRLGFGLSMAFKFDYYIVDEVTAVGD 156
Cdd:cd03297 85 alfphLNVRENLAFGLKRKRNREDRISVDELLDLLG-LDHLLNRYPAQLSGGEKQRVALARALAAQPELLLLDEPFSALD 163
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 446512897 157 ARFKEKCAQLFKERHKESSF--LMVSHSLNSLKEFCDVAIVFKNSYIIGY 204
Cdd:cd03297 164 RALRLQLLPELKQIKKNLNIpvIFVTHDLSEAEYLADRIVVMEDGRLQYI 213
|
|
| PhnK |
COG1101 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
1-63 |
7.74e-16 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 440718 [Multi-domain] Cd Length: 264 Bit Score: 73.97 E-value: 7.74e-16
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446512897 1 MIKIENLTKSYRTPTGR-HYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKII 63
Cdd:COG1101 1 MLELKNLSKTFNPGTVNeKRALDGLNLTIEEGDFVTVIGSNGAGKSTLLNAIAGSLPPDSGSIL 64
|
|
| ccmA |
TIGR01189 |
heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein ... |
20-181 |
1.02e-15 |
|
heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein encoded by ccmA in bacteria. An exception is, an arabidopsis protein. Quite likely this is encoded by an organelle. Bacterial c-type cytocromes are located on the periplasmic side of the cytoplasmic membrane. Several gene products encoded in a locus designated as 'ccm' are implicated in the transport and assembly of the functional cytochrome C. This cluster includes genes: ccmA;B;C;D;E;F;G and H. The posttranslational pathway includes the transport of heme moiety, the secretion of the apoprotein and the covalent attachment of the heme with the apoprotein. The proteins ccmA and B represent an ABC transporter; ccmC and D participate in heme transfer to ccmE, which function as a periplasmic heme chaperone. The presence of ccmF, G and H is suggested to be obligatory for the final functional assembly of cytochrome c. [Protein fate, Protein and peptide secretion and trafficking, Transport and binding proteins, Other]
Pssm-ID: 273491 [Multi-domain] Cd Length: 198 Bit Score: 72.39 E-value: 1.02e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 20 VFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKIITNKT------------ISWpVGLAGGFQGSLTGREN 87
Cdd:TIGR01189 15 LFEGLSFTLNAGEALQVTGPNGIGKTTLLRILAGLLRPDSGEVRWNGTplaeqrdephenILY-LGHLPGLKPELSALEN 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 88 VKFVARLY-AKQEELKEKIEFVeefaELGKYFDMPIKTYSSGMRSRLGFGLSMAFKFDYYIVDEVTAVGDARFKEKCAQL 166
Cdd:TIGR01189 94 LHFWAAIHgGAQRTIEDALAAV----GLTGFEDLPAAQLSAGQQRRLALARLWLSRRPLWILDEPTTALDKAGVALLAGL 169
|
170
....*....|....*.
gi 446512897 167 FKER-HKESSFLMVSH 181
Cdd:TIGR01189 170 LRAHlARGGIVLLTTH 185
|
|
| cbiO |
PRK13636 |
cobalt transporter ATP-binding subunit; Provisional |
1-202 |
1.94e-15 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184196 [Multi-domain] Cd Length: 283 Bit Score: 73.34 E-value: 1.94e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 1 MIKIENLtkSYRTPTGRHyVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKII-TNKTISWP-------- 71
Cdd:PRK13636 5 ILKVEEL--NYNYSDGTH-ALKGININIKKGEVTAILGGNGAGKSTLFQNLNGILKPSSGRILfDGKPIDYSrkglmklr 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 72 --VGLAggFQG------SLTGRENVKF-VARLYAKQEELKEKIEFVEEFAELGKYFDMPIKTYSSGMRSRLGFGLSMAFK 142
Cdd:PRK13636 82 esVGMV--FQDpdnqlfSASVYQDVSFgAVNLKLPEDEVRKRVDNALKRTGIEHLKDKPTHCLSFGQKKRVAIAGVLVME 159
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446512897 143 FDYYIVDEVTAVGDARFKEKCAQLFKERHKES--SFLMVSHSLNSLKEFCDVAIVFKNSYII 202
Cdd:PRK13636 160 PKVLVLDEPTAGLDPMGVSEIMKLLVEMQKELglTIIIATHDIDIVPLYCDNVFVMKEGRVI 221
|
|
| ABCC_cytochrome_bd |
cd03247 |
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome ... |
2-202 |
2.63e-15 |
|
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome bd biogenesis. The CydC and CydD proteins are important for the formation of cytochrome bd terminal oxidase of E. coli and it has been proposed that they were necessary for biosynthesis of the cytochrome bd quinol oxidase and for periplasmic c-type cytochromes. CydCD were proposed to determine a heterooligomeric complex important for heme export into the periplasm or to be involved in the maintenance of the proper redox state of the periplasmic space. In Bacillus subtilis, the absence of CydCD does not affect the presence of halo-cytochrome c in the membrane and this observation suggests that CydCD proteins are not involved in the export of heme in this organism.
Pssm-ID: 213214 [Multi-domain] Cd Length: 178 Bit Score: 70.80 E-value: 2.63e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 2 IKIENLTKSYrtPTGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKIITNKTiswPVGLAggfqgs 81
Cdd:cd03247 1 LSINNVSFSY--PEQEQQVLKNLSLELKQGEKIALLGRSGSGKSTLLQLLTGDLKPQQGEITLDGV---PVSDL------ 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 82 ltgrenvkfvarlyakQEELKEKIEFVEEFAELgkyFDMPI-----KTYSSGMRSRLGFGLSMAFKFDYYIVDEVTAVGD 156
Cdd:cd03247 70 ----------------EKALSSLISVLNQRPYL---FDTTLrnnlgRRFSGGERQRLALARILLQDAPIVLLDEPTVGLD 130
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 446512897 157 ARFKEKCAQLFKERHKESSFLMVSHSLNSLKEFcDVAIVFKNSYII 202
Cdd:cd03247 131 PITERQLLSLIFEVLKDKTLIWITHHLTGIEHM-DKILFLENGKII 175
|
|
| ABC_PotA_N |
cd03300 |
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and ... |
2-181 |
9.62e-15 |
|
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and the ATPase component of the spermidine/putrescine-preferential uptake system consisting of PotA, -B, -C, and -D. PotA has two domains with the N-terminal domain containing the ATPase activity and the residues required for homodimerization with PotA and heterdimerization with PotB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213267 [Multi-domain] Cd Length: 232 Bit Score: 70.34 E-value: 9.62e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 2 IKIENLTKSYrtptGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKI-ITNKTIS------WPVGL 74
Cdd:cd03300 1 IELENVSKFY----GGFVALDGVSLDIKEGEFFTLLGPSGCGKTTLLRLIAGFETPTSGEIlLDGKDITnlpphkRPVNT 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 75 AggFQG-----SLTGRENVKFVARL-YAKQEELKEKIEFVEEFAELGKYFDMPIKTYSSGMRSRLGFGLSMAFKFDYYIV 148
Cdd:cd03300 77 V--FQNyalfpHLTVFENIAFGLRLkKLPKAEIKERVAEALDLVQLEGYANRKPSQLSGGQQQRVAIARALVNEPKVLLL 154
|
170 180 190
....*....|....*....|....*....|....*
gi 446512897 149 DEVTAVGDARFKEKCAQLFKERHKE--SSFLMVSH 181
Cdd:cd03300 155 DEPLGALDLKLRKDMQLELKRLQKElgITFVFVTH 189
|
|
| ABC_HisP_GlnQ |
cd03262 |
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ... |
2-63 |
1.03e-14 |
|
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ATP-binding components of the bacterial periplasmic histidine and glutamine permeases, respectively. Histidine permease is a multi-subunit complex containing the HisQ and HisM integral membrane subunits and two copies of HisP. HisP has properties intermediate between those of integral and peripheral membrane proteins and is accessible from both sides of the membrane, presumably by its interaction with HisQ and HisM. The two HisP subunits form a homodimer within the complex. The domain structure of the amino acid uptake systems is typical for prokaryotic extracellular solute binding protein-dependent uptake systems. All of the amino acid uptake systems also have at least one, and in a few cases, two extracellular solute binding proteins located in the periplasm of Gram-negative bacteria, or attached to the cell membrane of Gram-positive bacteria. The best-studied member of the PAAT (polar amino acid transport) family is the HisJQMP system of S. typhimurium, where HisJ is the extracellular solute binding proteins and HisP is the ABC protein.
Pssm-ID: 213229 [Multi-domain] Cd Length: 213 Bit Score: 70.25 E-value: 1.03e-14
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446512897 2 IKIENLTKSYrtptGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKII 63
Cdd:cd03262 1 IEIKNLHKSF----GDFHVLKGIDLTVKKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTII 58
|
|
| ABCC_Protease_Secretion |
cd03246 |
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of ... |
2-62 |
1.26e-14 |
|
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of the protease secretion system PrtD, a 60-kDa integral membrane protein sharing 37% identity with HlyB, the ABC component of the alpha-hemolysin secretion pathway, in the C-terminal domain. They export degradative enzymes by using a type I protein secretion system and lack an N-terminal signal peptide, but contain a C-terminal secretion signal. The Type I secretion apparatus is made up of three components, an ABC transporter, a membrane fusion protein (MFP), and an outer membrane protein (OMP). For the HlyA transporter complex, HlyB (ABC transporter) and HlyD (MFP) reside in the inner membrane of E. coli. The OMP component is TolC, which is thought to interact with the MFP to form a continuous channel across the periplasm from the cytoplasm to the exterior. HlyB belongs to the family of ABC transporters, which are ubiquitous, ATP-dependent transmembrane pumps or channels. The spectrum of transport substrates ranges from inorganic ions, nutrients such as amino acids, sugars, or peptides, hydrophobic drugs, to large polypeptides, such as HlyA.
Pssm-ID: 213213 [Multi-domain] Cd Length: 173 Bit Score: 69.17 E-value: 1.26e-14
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446512897 2 IKIENLtkSYRTPTGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKI 62
Cdd:cd03246 1 LEVENV--SFRYPGAEPPVLRNVSFSIEPGESLAIIGPSGSGKSTLARLILGLLRPTSGRV 59
|
|
| cbiO |
PRK13637 |
energy-coupling factor transporter ATPase; |
2-202 |
1.32e-14 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237455 [Multi-domain] Cd Length: 287 Bit Score: 70.85 E-value: 1.32e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 2 IKIENLTKSY--RTPTGRHyVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKIITN-----------KTI 68
Cdd:PRK13637 3 IKIENLTHIYmeGTPFEKK-ALDNVNIEIEDGEFVGLIGHTGSGKSTLIQHLNGLLKPTSGKIIIDgvditdkkvklSDI 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 69 SWPVGLAggFQG------SLTGRENVKF-VARLYAKQEELKEKIEFVEEFAELG--KYFDMPIKTYSSGMRSRLGFGLSM 139
Cdd:PRK13637 82 RKKVGLV--FQYpeyqlfEETIEKDIAFgPINLGLSEEEIENRVKRAMNIVGLDyeDYKDKSPFELSGGQKRRVAIAGVV 159
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446512897 140 AFKFDYYIVDEVTAVGDARFKEKCAQLFKERHKE--SSFLMVSHSLNSLKEFCDVAIVFKNSYII 202
Cdd:PRK13637 160 AMEPKILILDEPTAGLDPKGRDEILNKIKELHKEynMTIILVSHSMEDVAKLADRIIVMNKGKCE 224
|
|
| ABCC_bacteriocin_exporters |
cd03245 |
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic ... |
10-202 |
1.48e-14 |
|
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic bacteriocins of lactic acid bacteria are produced as precursors which have N-terminal leader peptides that share similarities in amino acid sequence and contain a conserved processing site of two glycine residues in positions -1 and -2. A dedicated ATP-binding cassette (ABC) transporter is responsible for the proteolytic cleavage of the leader peptides and subsequent translocation of the bacteriocins across the cytoplasmic membrane.
Pssm-ID: 213212 [Multi-domain] Cd Length: 220 Bit Score: 69.93 E-value: 1.48e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 10 SYRTPTGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKIITNKTISW---PVGLAGG--------- 77
Cdd:cd03245 9 SFSYPNQEIPALDNVSLTIRAGEKVAIIGRVGSGKSTLLKLLAGLYKPTSGSVLLDGTDIRqldPADLRRNigyvpqdvt 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 78 -FQGSLtgRENVKFvARLYAKQEELKEKIEF--VEEFAEL-GKYFDMPI----KTYSSGMRSrlGFGLSMAFKFDYYIV- 148
Cdd:cd03245 89 lFYGTL--RDNITL-GAPLADDERILRAAELagVTDFVNKhPNGLDLQIgergRGLSGGQRQ--AVALARALLNDPPILl 163
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 446512897 149 -DEVTAVGD----ARFKEKCAQLFKERhkesSFLMVSHSLnSLKEFCDVAIVFKNSYII 202
Cdd:cd03245 164 lDEPTSAMDmnseERLKERLRQLLGDK----TLIIITHRP-SLLDLVDRIIVMDSGRIV 217
|
|
| ABC_CcmA_heme_exporter |
cd03231 |
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the ... |
20-167 |
1.51e-14 |
|
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the bacterial CcmAB transporter. The CCM family is involved in bacterial cytochrome c biogenesis. Cytochrome c maturation in E. coli requires the ccm operon, which encodes eight membrane proteins (CcmABCDEFGH). CcmE is a periplasmic heme chaperon that binds heme covalently and transfers it onto apocytochrome c in the presence of CcmF, CcmG, and CcmH. The CcmAB proteins represent an ABC transporter and the CcmCD proteins participate in heme transfer to CcmE.
Pssm-ID: 213198 [Multi-domain] Cd Length: 201 Bit Score: 69.44 E-value: 1.51e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 20 VFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKIITNKT------------ISWpVGLAGGFQGSLTGREN 87
Cdd:cd03231 15 LFSGLSFTLAAGEALQVTGPNGSGKTTLLRILAGLSPPLAGRVLLNGGpldfqrdsiargLLY-LGHAPGIKTTLSVLEN 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 88 VKFVARLYAkqeelKEKIEFVEEFAELGKYFDMPIKTYSSGMRSRLGFGLSMAFKFDYYIVDEVTAVGDARFKEKCAQLF 167
Cdd:cd03231 94 LRFWHADHS-----DEQVEEALARVGLNGFEDRPVAQLSAGQQRRVALARLLLSGRPLWILDEPTTALDKAGVARFAEAM 168
|
|
| CydD |
TIGR02857 |
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family ... |
2-195 |
1.58e-14 |
|
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex. Unfortunately, the gene symbol nomenclature adopted based on this operon in B. subtilis assigns cydC to the third gene in the operon where this gene is actually homologous to the E. coli cydD gene. We have chosen to name all homologs in this family in accordance with the precedence of publication of the E. coli name, CydD
Pssm-ID: 274323 [Multi-domain] Cd Length: 529 Bit Score: 71.93 E-value: 1.58e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 2 IKIENLTKSYRtptGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKIITN-------------KTI 68
Cdd:TIGR02857 322 LEFSGVSVAYP---GRRPALRPVSFTVPPGERVALVGPSGAGKSTLLNLLLGFVDPTEGSIAVNgvpladadadswrDQI 398
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 69 SWPVGLAGGFQGSLtgRENVKFvARLYAKQEELKEKIEFVE--EF-AELGKYFDMPI----KTYSSGMRSRLgfGLSMAF 141
Cdd:TIGR02857 399 AWVPQHPFLFAGTI--AENIRL-ARPDASDAEIREALERAGldEFvAALPQGLDTPIgeggAGLSGGQAQRL--ALARAF 473
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 142 KFDYYIV--DEVTAVGD----ARFKEKCAQLFKERhkesSFLMVSHSLNsLKEFCDVAIV 195
Cdd:TIGR02857 474 LRDAPLLllDEPTAHLDaeteAEVLEALRALAQGR----TVLLVTHRLA-LAALADRIVV 528
|
|
| COG4586 |
COG4586 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
1-62 |
2.07e-14 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 443643 [Multi-domain] Cd Length: 323 Bit Score: 70.89 E-value: 2.07e-14
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446512897 1 MIKIENLTKSYRTP--------TGRHYVF---------KDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKI 62
Cdd:COG4586 1 IIEVENLSKTYRVYekepglkgALKGLFRreyreveavDDISFTIEPGEIVGFIGPNGAGKSTTIKMLTGILVPTSGEV 79
|
|
| LivF |
COG0410 |
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid ... |
1-108 |
2.08e-14 |
|
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid transport and metabolism];
Pssm-ID: 440179 [Multi-domain] Cd Length: 236 Bit Score: 69.63 E-value: 2.08e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 1 MIKIENLTKSYrtptGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKI------ITNktisWPV-- 72
Cdd:COG0410 3 MLEVENLHAGY----GGIHVLHGVSLEVEEGEIVALLGRNGAGKTTLLKAISGLLPPRSGSIrfdgedITG----LPPhr 74
|
90 100 110 120
....*....|....*....|....*....|....*....|....*.
gi 446512897 73 ----GLA------GGFqGSLTGRENVKFVARLYAKQEELKEKIEFV 108
Cdd:COG0410 75 iarlGIGyvpegrRIF-PSLTVEENLLLGAYARRDRAEVRADLERV 119
|
|
| ABC_ABC_ChvD |
TIGR03719 |
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ... |
2-68 |
3.56e-14 |
|
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.
Pssm-ID: 274744 [Multi-domain] Cd Length: 552 Bit Score: 70.73 E-value: 3.56e-14
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446512897 2 IKIENLTKSYrtptGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKIITNKTI 68
Cdd:TIGR03719 323 IEAENLTKAF----GDKLLIDDLSFKLPPGGIVGVIGPNGAGKSTLFRMITGQEQPDSGTIEIGETV 385
|
|
| ABC_YhbG |
cd03218 |
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the ... |
2-150 |
3.83e-14 |
|
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the YhbG family are similar to members of the Mj1267_LivG family, which is involved in the transport of branched-chain amino acids. The genes yhbG and yhbN are located in a single operon and may function together in cell envelope during biogenesis. YhbG is the putative ATP-binding cassette component and YhbN is the putative periplasmic-binding protein. Depletion of each gene product leads to growth arrest, irreversible cell damage and loss of viability in E. coli. The YhbG homolog (NtrA) is essential in Rhizobium meliloti, a symbiotic nitrogen-fixing bacterium.
Pssm-ID: 213185 [Multi-domain] Cd Length: 232 Bit Score: 68.72 E-value: 3.83e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 2 IKIENLTKSYrtptGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKI------ITNKTISWPVGLA 75
Cdd:cd03218 1 LRAENLSKRY----GKRKVVNGVSLSVKQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGKIlldgqdITKLPMHKRARLG 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 76 GGF--Q-----GSLTGRENVKFVARL-YAKQEELKEKIEFV-EEFaELGKYFDMPIKTYSSGMRSRLGFGLSMAFKFDYY 146
Cdd:cd03218 77 IGYlpQeasifRKLTVEENILAVLEIrGLSKKEREEKLEELlEEF-HITHLRKSKASSLSGGERRRVEIARALATNPKFL 155
|
....
gi 446512897 147 IVDE 150
Cdd:cd03218 156 LLDE 159
|
|
| PRK11000 |
PRK11000 |
maltose/maltodextrin ABC transporter ATP-binding protein MalK; |
2-150 |
4.58e-14 |
|
maltose/maltodextrin ABC transporter ATP-binding protein MalK;
Pssm-ID: 182893 [Multi-domain] Cd Length: 369 Bit Score: 70.06 E-value: 4.58e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 2 IKIENLTKSYrtptGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKI-ITNKTISW--P----VGL 74
Cdd:PRK11000 4 VTLRNVTKAY----GDVVISKDINLDIHEGEFVVFVGPSGCGKSTLLRMIAGLEDITSGDLfIGEKRMNDvpPaergVGM 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 75 AggFQG-----SLTGRENVKFVARLY-AKQEELKEKIEFVEEFAELGKYFDMPIKTYSSGMRSRLGFGLSMAFKFDYYIV 148
Cdd:PRK11000 80 V--FQSyalypHLSVAENMSFGLKLAgAKKEEINQRVNQVAEVLQLAHLLDRKPKALSGGQRQRVAIGRTLVAEPSVFLL 157
|
..
gi 446512897 149 DE 150
Cdd:PRK11000 158 DE 159
|
|
| PRK13537 |
PRK13537 |
nodulation factor ABC transporter ATP-binding protein NodI; |
2-191 |
9.82e-14 |
|
nodulation factor ABC transporter ATP-binding protein NodI;
Pssm-ID: 237420 [Multi-domain] Cd Length: 306 Bit Score: 68.68 E-value: 9.82e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 2 IKIENLTKSYrtptGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKI-ITNKTIswP--------- 71
Cdd:PRK13537 8 IDFRNVEKRY----GDKLVVDGLSFHVQRGECFGLLGPNGAGKTTTLRMLLGLTHPDAGSIsLCGEPV--Psrarharqr 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 72 VGLAGGFQG---SLTGRENVKFVARLYA-KQEELKEKIEFVEEFAELGKYFDMPIKTYSSGMRSRLGFGLSMAFKFDYYI 147
Cdd:PRK13537 82 VGVVPQFDNldpDFTVRENLLVFGRYFGlSAAAARALVPPLLEFAKLENKADAKVGELSGGMKRRLTLARALVNDPDVLV 161
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 446512897 148 VDEVTAVGDARFKekcaQLFKERHKE-----SSFLMVSHSLNSLKEFCD 191
Cdd:PRK13537 162 LDEPTTGLDPQAR----HLMWERLRSllargKTILLTTHFMEEAERLCD 206
|
|
| ABC_cobalt_CbiO_domain2 |
cd03226 |
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of ... |
4-198 |
2.50e-13 |
|
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. The CbiMNQO family ABC transport system is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.
Pssm-ID: 213193 [Multi-domain] Cd Length: 205 Bit Score: 66.13 E-value: 2.50e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 4 IENLTKSYRTPTgrhYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKIITNKTISWPVGLAG------- 76
Cdd:cd03226 2 IENISFSYKKGT---EILDDLSLDLYAGEIIALTGKNGAGKTTLAKILAGLIKESSGSILLNGKPIKAKERRKsigyvmq 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 77 --GFQ-GSLTGRENVKFVARLYAKQEELKEKIefVEEFaELGKYFDMPIKTYSSGMRSRLGFGLSMAFKFDYYIVDEVTA 153
Cdd:cd03226 79 dvDYQlFTDSVREELLLGLKELDAGNEQAETV--LKDL-DLYALKERHPLSLSGGQKQRLAIAAALLSGKDLLIFDEPTS 155
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 446512897 154 VGDARFKEKCAQLFKERHKE-SSFLMVSHSLNSLKEFCDVAIVFKN 198
Cdd:cd03226 156 GLDYKNMERVGELIRELAAQgKAVIVITHDYEFLAKVCDRVLLLAN 201
|
|
| PRK13536 |
PRK13536 |
nodulation factor ABC transporter ATP-binding protein NodI; |
2-191 |
3.95e-13 |
|
nodulation factor ABC transporter ATP-binding protein NodI;
Pssm-ID: 237419 [Multi-domain] Cd Length: 340 Bit Score: 67.16 E-value: 3.95e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 2 IKIENLTKSYrtptGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKIitnKTISWPV--------- 72
Cdd:PRK13536 42 IDLAGVSKSY----GDKAVVNGLSFTVASGECFGLLGPNGAGKSTIARMILGMTSPDAGKI---TVLGVPVpararlara 114
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 73 --GLAGGFQG---SLTGRENVKFVARLYA-KQEELKEKIEFVEEFAELGKYFDMPIKTYSSGMRSRLGFGLSMAFKFDYY 146
Cdd:PRK13536 115 riGVVPQFDNldlEFTVRENLLVFGRYFGmSTREIEAVIPSLLEFARLESKADARVSDLSGGMKRRLTLARALINDPQLL 194
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 446512897 147 IVDEVTAVGD--ARfkekcaQLFKERHKE-----SSFLMVSHSLNSLKEFCD 191
Cdd:PRK13536 195 ILDEPTTGLDphAR------HLIWERLRSllargKTILLTTHFMEEAERLCD 240
|
|
| PRK15177 |
PRK15177 |
Vi polysaccharide ABC transporter ATP-binding protein VexC; |
34-190 |
4.19e-13 |
|
Vi polysaccharide ABC transporter ATP-binding protein VexC;
Pssm-ID: 185099 [Multi-domain] Cd Length: 213 Bit Score: 65.85 E-value: 4.19e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 34 VAFIGRNGAGKSTLLRMIGGIDRPDSGKIITNKTISWPVGLAGGFQGSLTGRENVKFVARLYAKQEElkEKIEFVEEFAE 113
Cdd:PRK15177 16 IGILAAPGSGKTTLTRLLCGLDAPDEGDFIGLRGDALPLGANSFILPGLTGEENARMMASLYGLDGD--EFSHFCYQLTQ 93
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446512897 114 LGKYFDMPIKTYSSGMRSRLGFGLSMAFKFDYYIVDEVTAVGDARFKEKCAQLFKERHKESSFLMVSHSLNSLKEFC 190
Cdd:PRK15177 94 LEQCYTDRVSEYSVTMKTHLAFAINLLLPCRLYIADGKLYTGDNATQLRMQAALACQLQQKGLIVLTHNPRLIKEHC 170
|
|
| LptB |
COG1137 |
ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope ... |
1-111 |
4.26e-13 |
|
ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440752 [Multi-domain] Cd Length: 240 Bit Score: 66.21 E-value: 4.26e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 1 MIKIENLTKSYRtptGRHyVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKI------ITNktisWPV-- 72
Cdd:COG1137 3 TLEAENLVKSYG---KRT-VVKDVSLEVNQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGRIfldgedITH----LPMhk 74
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 446512897 73 ----GL------AGGFQGsLTGRENVKFVARL-YAKQEELKEKIEF-VEEF 111
Cdd:COG1137 75 rarlGIgylpqeASIFRK-LTVEDNILAVLELrKLSKKEREERLEElLEEF 124
|
|
| ssuB |
PRK11247 |
aliphatic sulfonates transport ATP-binding subunit; Provisional |
4-67 |
6.63e-13 |
|
aliphatic sulfonates transport ATP-binding subunit; Provisional
Pssm-ID: 183055 [Multi-domain] Cd Length: 257 Bit Score: 65.85 E-value: 6.63e-13
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446512897 4 IENLTKSYrtptGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKIITNKT 67
Cdd:PRK11247 15 LNAVSKRY----GERTVLNQLDLHIPAGQFVAVVGRSGCGKSTLLRLLAGLETPSAGELLAGTA 74
|
|
| cbiO |
PRK13644 |
energy-coupling factor transporter ATPase; |
1-210 |
8.00e-13 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 106587 [Multi-domain] Cd Length: 274 Bit Score: 65.78 E-value: 8.00e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 1 MIKIENLTKSYrtPTGRHyVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKIITN----------KTISW 70
Cdd:PRK13644 1 MIRLENVSYSY--PDGTP-ALENINLVIKKGEYIGIIGKNGSGKSTLALHLNGLLRPQKGKVLVSgidtgdfsklQGIRK 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 71 PVGLAggFQGSLT---GR---ENVKF-VARLYAKQEELKEKIEFVEEFAELGKYFDMPIKTYSSGMRSRLGFGLSMAFKF 143
Cdd:PRK13644 78 LVGIV--FQNPETqfvGRtveEDLAFgPENLCLPPIEIRKRVDRALAEIGLEKYRHRSPKTLSGGQGQCVALAGILTMEP 155
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 144 DYYIVDEVTAVGDARFKEKCAQLFKERH-KESSFLMVSHSLNSLKEfCDVAIVFKNSYII--GYYENVQS 210
Cdd:PRK13644 156 ECLIFDEVTSMLDPDSGIAVLERIKKLHeKGKTIVYITHNLEELHD-ADRIIVMDRGKIVleGEPENVLS 224
|
|
| PRK11819 |
PRK11819 |
putative ABC transporter ATP-binding protein; Reviewed |
2-68 |
1.01e-12 |
|
putative ABC transporter ATP-binding protein; Reviewed
Pssm-ID: 236992 [Multi-domain] Cd Length: 556 Bit Score: 66.30 E-value: 1.01e-12
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446512897 2 IKIENLTKSYrtptGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKIITNKTI 68
Cdd:PRK11819 325 IEAENLSKSF----GDRLLIDDLSFSLPPGGIVGIIGPNGAGKSTLFKMITGQEQPDSGTIKIGETV 387
|
|
| ABC_TM1139_LivF_branched |
cd03224 |
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of ... |
2-138 |
1.17e-12 |
|
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of the LIV-I bacterial ABC-type two-component transport system that imports neutral, branched-chain amino acids. The E. coli branched-chain amino acid transporter comprises a heterodimer of ABC transporters (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules.
Pssm-ID: 213191 [Multi-domain] Cd Length: 222 Bit Score: 64.76 E-value: 1.17e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 2 IKIENLTKSYrtptGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKI------ITNktisWPV--- 72
Cdd:cd03224 1 LEVENLNAGY----GKSQILFGVSLTVPEGEIVALLGRNGAGKTTLLKTIMGLLPPRSGSIrfdgrdITG----LPPher 72
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446512897 73 ---GLAGGFQG-----SLTGRENVKfVARLYAKQEELKEKIEFV-EEFAELGKyfdmpiktyssgMRSRLGFGLS 138
Cdd:cd03224 73 araGIGYVPEGrrifpELTVEENLL-LGAYARRRAKRKARLERVyELFPRLKE------------RRKQLAGTLS 134
|
|
| ABC_FtsE |
cd03292 |
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where ... |
2-181 |
1.92e-12 |
|
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages
Pssm-ID: 213259 [Multi-domain] Cd Length: 214 Bit Score: 63.97 E-value: 1.92e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 2 IKIENLTKSYrtPTGrHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKIITNKT------------IS 69
Cdd:cd03292 1 IEFINVTKTY--PNG-TAALDGINISISAGEFVFLVGPSGAGKSTLLKLIYKEELPTSGTIRVNGQdvsdlrgraipyLR 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 70 WPVGLAggFQGS-----LTGRENVKFVARL-YAKQEELKEKIEFVEEFAEL-GKYFDMPIKtYSSGMRSRLGFGLSMAFK 142
Cdd:cd03292 78 RKIGVV--FQDFrllpdRNVYENVAFALEVtGVPPREIRKRVPAALELVGLsHKHRALPAE-LSGGEQQRVAIARAIVNS 154
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 446512897 143 FDYYIVDEVTAVGDARFKEKCAQLFKERHKE-SSFLMVSH 181
Cdd:cd03292 155 PTILIADEPTGNLDPDTTWEIMNLLKKINKAgTTVVVATH 194
|
|
| MdlB |
COG1132 |
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms]; |
2-62 |
3.78e-12 |
|
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];
Pssm-ID: 440747 [Multi-domain] Cd Length: 579 Bit Score: 64.80 E-value: 3.78e-12
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446512897 2 IKIENLTKSYRtptGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKI 62
Cdd:COG1132 340 IEFENVSFSYP---GDRPVLKDISLTIPPGETVALVGPSGSGKSTLVNLLLRFYDPTSGRI 397
|
|
| MK0520 |
COG2401 |
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction ... |
2-159 |
3.90e-12 |
|
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction only];
Pssm-ID: 441957 [Multi-domain] Cd Length: 222 Bit Score: 63.05 E-value: 3.90e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 2 IKIENLTKSYRTPTGR-------------------HYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGI--DRPDSG 60
Cdd:COG2401 8 FVLMRVTKVYSSVLDLservaivleafgvelrvveRYVLRDLNLEIEPGEIVLIVGASGSGKSTLLRLLAGAlkGTPVAG 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 61 KIITnKTISWPvglaggfqgsltgrENVKFVARLYAKQeELKEKIEF------VEEFAELGKYfdmpiKTYSSGMRSRLG 134
Cdd:COG2401 88 CVDV-PDNQFG--------------REASLIDAIGRKG-DFKDAVELlnavglSDAVLWLRRF-----KELSTGQKFRFR 146
|
170 180
....*....|....*....|....*
gi 446512897 135 FGLSMAFKFDYYIVDEVTAVGDARF 159
Cdd:COG2401 147 LALLLAERPKLLVIDEFCSHLDRQT 171
|
|
| ABCD_peroxisomal_ALDP |
cd03223 |
ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding ... |
2-182 |
4.06e-12 |
|
ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding cassette transporter (Pat) is involved in the import of very long-chain fatty acids (VLCFA) into the peroxisome. The peroxisomal membrane forms a permeability barrier for a wide variety of metabolites required for and formed during fatty acid beta-oxidation. To communicate with the cytoplasm and mitochondria, peroxisomes need dedicated proteins to transport such hydrophilic molecules across their membranes. X-linked adrenoleukodystrophy (X-ALD) is caused by mutations in the ALD gene, which encodes ALDP (adrenoleukodystrophy protein ), a peroxisomal integral membrane protein that is a member of the ATP-binding cassette (ABC) transporter protein family. The disease is characterized by a striking and unpredictable variation in phenotypic expression. Phenotypes include the rapidly progressive childhood cerebral form (CCALD), the milder adult form, adrenomyeloneuropathy (AMN), and variants without neurologic involvement (i.e. asymptomatic).
Pssm-ID: 213190 [Multi-domain] Cd Length: 166 Bit Score: 62.17 E-value: 4.06e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 2 IKIENLTksYRTPTGRHYVfKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIdrpdsgkiitnktisWPVGlaggfQGS 81
Cdd:cd03223 1 IELENLS--LATPDGRVLL-KDLSFEIKPGDRLLITGPSGTGKSSLFRALAGL---------------WPWG-----SGR 57
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 82 LT--GRENVKFVA-RLYAKQEELKEKIEFveefaelgkyfdmP-IKTYSSGMRSRLGFGLSMAFKFDYYIVDEVTAVGDA 157
Cdd:cd03223 58 IGmpEGEDLLFLPqRPYLPLGTLREQLIY-------------PwDDVLSGGEQQRLAFARLLLHKPKFVFLDEATSALDE 124
|
170 180
....*....|....*....|....*
gi 446512897 158 RFKEKCAQLFKERHkeSSFLMVSHS 182
Cdd:cd03223 125 ESEDRLYQLLKELG--ITVISVGHR 147
|
|
| PRK13541 |
PRK13541 |
cytochrome c biogenesis protein CcmA; Provisional |
23-151 |
4.40e-12 |
|
cytochrome c biogenesis protein CcmA; Provisional
Pssm-ID: 184128 [Multi-domain] Cd Length: 195 Bit Score: 62.58 E-value: 4.40e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 23 DLNIE-IPSgkSVAFI-GRNGAGKSTLLRMIGGIDRPDSGKI----ITNKTISWP----VGLAGGFQGSLTGRENVKFVA 92
Cdd:PRK13541 18 DLSITfLPS--AITYIkGANGCGKSSLLRMIAGIMQPSSGNIyyknCNINNIAKPyctyIGHNLGLKLEMTVFENLKFWS 95
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*....
gi 446512897 93 RLYAKQEELKEKIEFVeefaELGKYFDMPIKTYSSGMRSRLGFGLSMAFKFDYYIVDEV 151
Cdd:PRK13541 96 EIYNSAETLYAAIHYF----KLHDLLDEKCYSLSSGMQKIVAIARLIACQSDLWLLDEV 150
|
|
| cbiO |
PRK13643 |
energy-coupling factor transporter ATPase; |
1-202 |
6.55e-12 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184203 [Multi-domain] Cd Length: 288 Bit Score: 63.60 E-value: 6.55e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 1 MIKIENLTKSYR--TPTGRHYVFkDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGK------IITN------- 65
Cdd:PRK13643 1 MIKFEKVNYTYQpnSPFASRALF-DIDLEVKKGSYTALIGHTGSGKSTLLQHLNGLLQPTEGKvtvgdiVVSStskqkei 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 66 KTISWPVGLAGGFQGSLTGRE----NVKFVARLYAKQEELKEKI--EFVEEFAELGKYFDMPIKTYSSGMRSRLGFGLSM 139
Cdd:PRK13643 80 KPVRKKVGVVFQFPESQLFEEtvlkDVAFGPQNFGIPKEKAEKIaaEKLEMVGLADEFWEKSPFELSGGQMRRVAIAGIL 159
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446512897 140 AFKFDYYIVDEVTAVGDARFKEKCAQLFKERHKE-SSFLMVSHSLNSLKEFCDVAIVFKNSYII 202
Cdd:PRK13643 160 AMEPEVLVLDEPTAGLDPKARIEMMQLFESIHQSgQTVVLVTHLMDDVADYADYVYLLEKGHII 223
|
|
| hmuV |
PRK13548 |
hemin importer ATP-binding subunit; Provisional |
1-62 |
7.28e-12 |
|
hemin importer ATP-binding subunit; Provisional
Pssm-ID: 237422 [Multi-domain] Cd Length: 258 Bit Score: 62.87 E-value: 7.28e-12
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446512897 1 MIKIENLTKSYrtptGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKI 62
Cdd:PRK13548 2 MLEARNLSVRL----GGRTLLDDVSLTLRPGEVVAILGPNGAGKSTLLRALSGELSPDSGEV 59
|
|
| PRK11174 |
PRK11174 |
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed |
24-210 |
8.24e-12 |
|
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
Pssm-ID: 236870 [Multi-domain] Cd Length: 588 Bit Score: 63.71 E-value: 8.24e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 24 LNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIdRPDSGKIITN-------------KTISWpVG----LaggFQGSLtgRE 86
Cdd:PRK11174 369 LNFTLPAGQRIALVGPSGAGKTSLLNALLGF-LPYQGSLKINgielreldpeswrKHLSW-VGqnpqL---PHGTL--RD 441
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 87 NVKFvARLYAKQEELKEKIE--FVEEF-AELGKYFDMPIKTYSSGMR----SRLGFGLSMAFKFDYYIVDEVTAVGDARF 159
Cdd:PRK11174 442 NVLL-GNPDASDEQLQQALEnaWVSEFlPLLPQGLDTPIGDQAAGLSvgqaQRLALARALLQPCQLLLLDEPTASLDAHS 520
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 446512897 160 KEKCAQLFKERHKESSFLMVSHSLNSLKEfCDVAIVFKNSYII--GYYENVQS 210
Cdd:PRK11174 521 EQLVMQALNAASRRQTTLMVTHQLEDLAQ-WDQIWVMQDGQIVqqGDYAELSQ 572
|
|
| COG4559 |
COG4559 |
ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism]; |
1-62 |
9.29e-12 |
|
ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443620 [Multi-domain] Cd Length: 258 Bit Score: 62.44 E-value: 9.29e-12
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446512897 1 MIKIENLtkSYRTptGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKI 62
Cdd:COG4559 1 MLEAENL--SVRL--GGRTLLDDVSLTLRPGELTAIIGPNGAGKSTLLKLLTGELTPSSGEV 58
|
|
| PRK10851 |
PRK10851 |
sulfate/thiosulfate ABC transporter ATP-binding protein CysA; |
2-62 |
1.15e-11 |
|
sulfate/thiosulfate ABC transporter ATP-binding protein CysA;
Pssm-ID: 182778 [Multi-domain] Cd Length: 353 Bit Score: 63.18 E-value: 1.15e-11
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446512897 2 IKIENLTKSYrtptGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKI 62
Cdd:PRK10851 3 IEIANIKKSF----GRTQVLNDISLDIPSGQMVALLGPSGSGKTTLLRIIAGLEHQTSGHI 59
|
|
| PRK13538 |
PRK13538 |
cytochrome c biogenesis heme-transporting ATPase CcmA; |
1-132 |
1.88e-11 |
|
cytochrome c biogenesis heme-transporting ATPase CcmA;
Pssm-ID: 184125 [Multi-domain] Cd Length: 204 Bit Score: 60.97 E-value: 1.88e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 1 MIKIENLTKSyRtptGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKIITN-KTIS---------- 69
Cdd:PRK13538 1 MLEARNLACE-R---DERILFSGLSFTLNAGELVQIEGPNGAGKTSLLRILAGLARPDAGEVLWQgEPIRrqrdeyhqdl 76
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446512897 70 -WpVGLAGGFQGSLTGRENVKFVARLYAKQEElkEKIEFVEEFAELGKYFDMPIKTYSSGMRSR 132
Cdd:PRK13538 77 lY-LGHQPGIKTELTALENLRFYQRLHGPGDD--EALWEALAQVGLAGFEDVPVRQLSAGQQRR 137
|
|
| ThiQ |
COG3840 |
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism]; |
1-65 |
2.09e-11 |
|
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];
Pssm-ID: 443051 [Multi-domain] Cd Length: 232 Bit Score: 61.31 E-value: 2.09e-11
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446512897 1 MIKIENLTKSYRtptgrHYVFKdLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKIITN 65
Cdd:COG3840 1 MLRLDDLTYRYG-----DFPLR-FDLTIAAGERVAILGPSGAGKSTLLNLIAGFLPPDSGRILWN 59
|
|
| PhnL |
COG4778 |
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion ... |
1-63 |
2.53e-11 |
|
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion transport and metabolism];
Pssm-ID: 443809 [Multi-domain] Cd Length: 229 Bit Score: 60.91 E-value: 2.53e-11
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446512897 1 MIKIENLTKSY--------RTPtgrhyVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKII 63
Cdd:COG4778 4 LLEVENLSKTFtlhlqggkRLP-----VLDGVSFSVAAGECVALTGPSGAGKSTLLKCIYGNYLPDSGSIL 69
|
|
| fecE |
PRK11231 |
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE; |
1-69 |
4.10e-11 |
|
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;
Pssm-ID: 183044 [Multi-domain] Cd Length: 255 Bit Score: 60.80 E-value: 4.10e-11
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 1 MIKIENLTKSYrtptGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKI-ITNKTIS 69
Cdd:PRK11231 2 TLRTENLTVGY----GTKRILNDLSLSLPTGKITALIGPNGCGKSTLLKCFARLLTPQSGTVfLGDKPIS 67
|
|
| ABCC_MRP_domain2 |
cd03244 |
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C ... |
2-204 |
4.29e-11 |
|
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resistance lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213211 [Multi-domain] Cd Length: 221 Bit Score: 60.20 E-value: 4.29e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 2 IKIENLTKSYRtPTGRhYVFKDLNIEIPSGKSVAFIGRNGAGKST----LLRMIggidRPDSGKI-ITNKTISwPVGL-- 74
Cdd:cd03244 3 IEFKNVSLRYR-PNLP-PVLKNISFSIKPGEKVGIVGRTGSGKSSlllaLFRLV----ELSSGSIlIDGVDIS-KIGLhd 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 75 -----------AGGFQGSLtgRENVKFvaRLYAKQEELKEKIEFV---EEFAELGKYFDMPIKT----YSSGMRSRLGFG 136
Cdd:cd03244 76 lrsrisiipqdPVLFSGTI--RSNLDP--FGEYSDEELWQALERVglkEFVESLPGGLDTVVEEggenLSVGQRQLLCLA 151
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446512897 137 LSMAFKFDYYIVDEVTAVGDARFKEKCAQLFKERHKESSFLMVSHSLNSLKEfCDVAIVFKNSYIIGY 204
Cdd:cd03244 152 RALLRKSKILVLDEATASVDPETDALIQKTIREAFKDCTVLTIAHRLDTIID-SDRILVLDKGRVVEF 218
|
|
| PRK11160 |
PRK11160 |
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed |
2-202 |
5.80e-11 |
|
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
Pssm-ID: 236865 [Multi-domain] Cd Length: 574 Bit Score: 61.38 E-value: 5.80e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 2 IKIENLTKSYrtPTGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKIITNKT-------------- 67
Cdd:PRK11160 339 LTLNNVSFTY--PDQPQPVLKGLSLQIKAGEKVALLGRTGCGKSTLLQLLTRAWDPQQGEILLNGQpiadyseaalrqai 416
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 68 --ISWPVGLaggFQGSLtgRENVKFVARLyAKQEELKEKIEFV--EEFAELGKYFDMPI----KTYSSGMRSRLgfGLSM 139
Cdd:PRK11160 417 svVSQRVHL---FSATL--RDNLLLAAPN-ASDEALIEVLQQVglEKLLEDDKGLNAWLgeggRQLSGGEQRRL--GIAR 488
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446512897 140 AFKFDYYIV--DEVTAVGDARFKEKCAQLFKERHKESSFLMVSHSLNSLKEFcDVAIVFKNSYII 202
Cdd:PRK11160 489 ALLHDAPLLllDEPTEGLDAETERQILELLAEHAQNKTVLMITHRLTGLEQF-DRICVMDNGQII 552
|
|
| MglA |
COG1129 |
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; |
1-63 |
6.40e-11 |
|
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440745 [Multi-domain] Cd Length: 497 Bit Score: 61.19 E-value: 6.40e-11
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446512897 1 MIKIENLTKSYrtptGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKII 63
Cdd:COG1129 4 LLEMRGISKSF----GGVKALDGVSLELRPGEVHALLGENGAGKSTLMKILSGVYQPDSGEIL 62
|
|
| PRK13540 |
PRK13540 |
cytochrome c biogenesis protein CcmA; Provisional |
1-190 |
7.30e-11 |
|
cytochrome c biogenesis protein CcmA; Provisional
Pssm-ID: 184127 [Multi-domain] Cd Length: 200 Bit Score: 59.19 E-value: 7.30e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 1 MIKIENLTKSYRTptgrHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKI------ITNKTISWP--- 71
Cdd:PRK13540 1 MLDVIELDFDYHD----QPLLQQISFHLPAGGLLHLKGSNGAGKTTLLKLIAGLLNPEKGEIlferqsIKKDLCTYQkql 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 72 --VGLAGGFQGSLTGRENVKFVARLYAKQEELKEKIEFVeefaELGKYFDMPIKTYSSGMRSRLGFGLSMAFKFDYYIVD 149
Cdd:PRK13540 77 cfVGHRSGINPYLTLRENCLYDIHFSPGAVGITELCRLF----SLEHLIDYPCGLLSSGQKRQVALLRLWMSKAKLWLLD 152
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 446512897 150 EVTAVGDARFKEKCAQLFKE-RHKESSFLMVSH---SLN--SLKEFC 190
Cdd:PRK13540 153 EPLVALDELSLLTIITKIQEhRAKGGAVLLTSHqdlPLNkaDYEEYH 199
|
|
| ugpC |
PRK11650 |
sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC; |
1-62 |
9.07e-11 |
|
sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;
Pssm-ID: 236947 [Multi-domain] Cd Length: 356 Bit Score: 60.24 E-value: 9.07e-11
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446512897 1 MIKIENLTKSYrtpTGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKI 62
Cdd:PRK11650 3 GLKLQAVRKSY---DGKTQVIKGIDLDVADGEFIVLVGPSGCGKSTLLRMVAGLERITSGEI 61
|
|
| cbiO |
PRK13641 |
energy-coupling factor transporter ATPase; |
23-202 |
2.09e-10 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237456 [Multi-domain] Cd Length: 287 Bit Score: 59.07 E-value: 2.09e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 23 DLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKI------ITNKT-------ISWPVGLAGGFQGSL----TGR 85
Cdd:PRK13641 25 NISFELEEGSFVALVGHTGSGKSTLMQHFNALLKPSSGTItiagyhITPETgnknlkkLRKKVSLVFQFPEAQlfenTVL 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 86 ENVKFVARLYAKQEElKEKIEFVEEFAELGKYFDMPIKT---YSSGMRSRLGFGLSMAFKFDYYIVDEVTAVGDARFKEK 162
Cdd:PRK13641 105 KDVEFGPKNFGFSED-EAKEKALKWLKKVGLSEDLISKSpfeLSGGQMRRVAIAGVMAYEPEILCLDEPAAGLDPEGRKE 183
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 446512897 163 CAQLFKERHKES-SFLMVSHSLNSLKEFCDVAIVFKNSYII 202
Cdd:PRK13641 184 MMQLFKDYQKAGhTVILVTHNMDDVAEYADDVLVLEHGKLI 224
|
|
| cbiO |
PRK13649 |
energy-coupling factor transporter ATPase; |
2-202 |
2.97e-10 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184208 [Multi-domain] Cd Length: 280 Bit Score: 58.60 E-value: 2.97e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 2 IKIENLTKSYR--TPTGRHYVFkDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKI------ITN-------K 66
Cdd:PRK13649 3 INLQNVSYTYQagTPFEGRALF-DVNLTIEDGSYTAFIGHTGSGKSTIMQLLNGLHVPTQGSVrvddtlITStsknkdiK 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 67 TISWPVGLAGGFQGSLTGRENV-KFVA----RLYAKQEE----LKEKIEFVEEFAELgkyFDMPIKTYSSGMRSRLGFGL 137
Cdd:PRK13649 82 QIRKKVGLVFQFPESQLFEETVlKDVAfgpqNFGVSQEEaealAREKLALVGISESL---FEKNPFELSGGQMRRVAIAG 158
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446512897 138 SMAFKFDYYIVDEVTAVGDARFKEKCAQLFKERHKES-SFLMVSHSLNSLKEFCDVAIVFKNSYII 202
Cdd:PRK13649 159 ILAMEPKILVLDEPTAGLDPKGRKELMTLFKKLHQSGmTIVLVTHLMDDVANYADFVYVLEKGKLV 224
|
|
| PRK14247 |
PRK14247 |
phosphate ABC transporter ATP-binding protein; Provisional |
2-181 |
3.19e-10 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172735 [Multi-domain] Cd Length: 250 Bit Score: 58.39 E-value: 3.19e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 2 IKIENLTKSYrtptGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRM------------IGGIDRPDSGKIITNKTIS 69
Cdd:PRK14247 4 IEIRDLKVSF----GQVEVLDGVNLEIPDNTITALMGPSGSGKSTLLRVfnrlielypearVSGEVYLDGQDIFKMDVIE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 70 WPVGLAGGFQ-----GSLTGRENVKF---VARLYAKQEELKEKIEFVEEFAEL----GKYFDMPIKTYSSGMRSRLGFGL 137
Cdd:PRK14247 80 LRRRVQMVFQipnpiPNLSIFENVALglkLNRLVKSKKELQERVRWALEKAQLwdevKDRLDAPAGKLSGGQQQRLCIAR 159
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 446512897 138 SMAFKFDYYIVDEVTAVGDARFKEKCAQLFKERHKESSFLMVSH 181
Cdd:PRK14247 160 ALAFQPEVLLADEPTANLDPENTAKIESLFLELKKDMTIVLVTH 203
|
|
| ABCC_MRP_domain1 |
cd03250 |
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This ... |
2-69 |
3.36e-10 |
|
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This subfamily is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213217 [Multi-domain] Cd Length: 204 Bit Score: 57.48 E-value: 3.36e-10
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446512897 2 IKIENLTKSY-RTPTGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKIITNKTIS 69
Cdd:cd03250 1 ISVEDASFTWdSGEQETSFTLKDINLEVPKGELVAIVGPVGSGKSSLLSALLGELEKLSGSVSVPGSIA 69
|
|
| nikE |
PRK10419 |
nickel ABC transporter ATP-binding protein NikE; |
1-62 |
3.71e-10 |
|
nickel ABC transporter ATP-binding protein NikE;
Pssm-ID: 236689 [Multi-domain] Cd Length: 268 Bit Score: 58.16 E-value: 3.71e-10
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446512897 1 MIKIENLTKSYRT-----PTGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKI 62
Cdd:PRK10419 3 LLNVSGLSHHYAHgglsgKHQHQTVLNNVSLSLKSGETVALLGRSGCGKSTLARLLVGLESPSQGNV 69
|
|
| cbiO |
PRK13634 |
cobalt transporter ATP-binding subunit; Provisional |
2-203 |
3.93e-10 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237454 [Multi-domain] Cd Length: 290 Bit Score: 58.11 E-value: 3.93e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 2 IKIENLTKSY--RTPTGRHYVFkDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKI-ITNKTISwpvglAGGF 78
Cdd:PRK13634 3 ITFQKVEHRYqyKTPFERRALY-DVNVSIPSGSYVAIIGHTGSGKSTLLQHLNGLLQPTSGTVtIGERVIT-----AGKK 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 79 QGSL-TGRENVKFVARLYAKQ--EELKEK-IEF--------VEEFAELGKY----------------FDMpiktySSGMR 130
Cdd:PRK13634 77 NKKLkPLRKKVGIVFQFPEHQlfEETVEKdICFgpmnfgvsEEDAKQKAREmielvglpeellarspFEL-----SGGQM 151
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446512897 131 SRLGFGLSMAFKFDYYIVDEVTAVGDARFKEKCAQLFKERHKES--SFLMVSHSLNSLKEFCDVAIVFKNSYIIG 203
Cdd:PRK13634 152 RRVAIAGVLAMEPEVLVLDEPTAGLDPKGRKEMMEMFYKLHKEKglTTVLVTHSMEDAARYADQIVVMHKGTVFL 226
|
|
| PRK15064 |
PRK15064 |
ABC transporter ATP-binding protein; Provisional |
4-62 |
3.97e-10 |
|
ABC transporter ATP-binding protein; Provisional
Pssm-ID: 237894 [Multi-domain] Cd Length: 530 Bit Score: 58.75 E-value: 3.97e-10
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 446512897 4 IENLTKSYrtptGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKI 62
Cdd:PRK15064 322 VENLTKGF----DNGPLFKNLNLLLEAGERLAIIGENGVGKTTLLRTLVGELEPDSGTV 376
|
|
| PRK11831 |
PRK11831 |
phospholipid ABC transporter ATP-binding protein MlaF; |
16-62 |
4.21e-10 |
|
phospholipid ABC transporter ATP-binding protein MlaF;
Pssm-ID: 236997 [Multi-domain] Cd Length: 269 Bit Score: 57.85 E-value: 4.21e-10
10 20 30 40
....*....|....*....|....*....|....*....|....*..
gi 446512897 16 GRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKI 62
Cdd:PRK11831 18 GNRCIFDNISLTVPRGKITAIMGPSGIGKTTLLRLIGGQIAPDHGEI 64
|
|
| met_CoM_red_A2 |
TIGR03269 |
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ... |
2-65 |
5.17e-10 |
|
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]
Pssm-ID: 132313 [Multi-domain] Cd Length: 520 Bit Score: 58.66 E-value: 5.17e-10
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446512897 2 IKIENLTKSYrtptGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGID--RPDSGKIITN 65
Cdd:TIGR03269 1 IEVKNLTKKF----DGKEVLKNISFTIEEGEVLGILGRSGAGKSVLMHVLRGMDqyEPTSGRIIYH 62
|
|
| potG |
PRK11607 |
putrescine ABC transporter ATP-binding subunit PotG; |
1-63 |
5.94e-10 |
|
putrescine ABC transporter ATP-binding subunit PotG;
Pssm-ID: 183226 [Multi-domain] Cd Length: 377 Bit Score: 58.31 E-value: 5.94e-10
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446512897 1 MIKIENLTKSYrtpTGRHYVfKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKII 63
Cdd:PRK11607 19 LLEIRNLTKSF---DGQHAV-DDVSLTIYKGEIFALLGASGCGKSTLLRMLAGFEQPTAGQIM 77
|
|
| CydC |
TIGR02868 |
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family ... |
10-157 |
6.83e-10 |
|
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex.
Pssm-ID: 274331 [Multi-domain] Cd Length: 530 Bit Score: 58.14 E-value: 6.83e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 10 SYRTPTGRHyVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKIITN-------------KTISWPVGLAG 76
Cdd:TIGR02868 341 SAGYPGAPP-VLDGVSLDLPPGERVAILGPSGSGKSTLLATLAGLLDPLQGEVTLDgvpvssldqdevrRRVSVCAQDAH 419
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 77 GFQGSLtgRENVKfVARLYAKQEELKEKIEFV---EEFAELGKYFDMPI----KTYSSGMRSRLGFGLSMAFKFDYYIVD 149
Cdd:TIGR02868 420 LFDTTV--RENLR-LARPDATDEELWAALERVglaDWLRALPDGLDTVLgeggARLSGGERQRLALARALLADAPILLLD 496
|
....*...
gi 446512897 150 EVTAVGDA 157
Cdd:TIGR02868 497 EPTEHLDA 504
|
|
| PRK10253 |
PRK10253 |
iron-enterobactin ABC transporter ATP-binding protein; |
5-202 |
7.53e-10 |
|
iron-enterobactin ABC transporter ATP-binding protein;
Pssm-ID: 182336 [Multi-domain] Cd Length: 265 Bit Score: 57.30 E-value: 7.53e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 5 ENLTKSYrtptGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKI---------ITNKTISWPVGLA 75
Cdd:PRK10253 11 EQLTLGY----GKYTVAENLTVEIPDGHFTAIIGPNGCGKSTLLRTLSRLMTPAHGHVwldgehiqhYASKEVARRIGLL 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 76 ---GGFQGSLTGREnvkFVAR-------LYAK-QEELKEKIEFVEEFAELGKYFDMPIKTYSSGMRSRLGFGLSMAFKFD 144
Cdd:PRK10253 87 aqnATTPGDITVQE---LVARgryphqpLFTRwRKEDEEAVTKAMQATGITHLADQSVDTLSGGQRQRAWIAMVLAQETA 163
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 145 YYIVDEVTAVGDARFKEKCAQLFKERHKESSFLM--VSHSLNSLKEFCDVAIVFKNSYII 202
Cdd:PRK10253 164 IMLLDEPTTWLDISHQIDLLELLSELNREKGYTLaaVLHDLNQACRYASHLIALREGKIV 223
|
|
| fbpC |
PRK11432 |
ferric ABC transporter ATP-binding protein; |
4-68 |
7.92e-10 |
|
ferric ABC transporter ATP-binding protein;
Pssm-ID: 183133 [Multi-domain] Cd Length: 351 Bit Score: 57.81 E-value: 7.92e-10
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446512897 4 IENLTKSYrtptGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKI------ITNKTI 68
Cdd:PRK11432 9 LKNITKRF----GSNTVIDNLNLTIKQGTMVTLLGPSGCGKTTVLRLVAGLEKPTEGQIfidgedVTHRSI 75
|
|
| PRK11264 |
PRK11264 |
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional |
1-62 |
8.16e-10 |
|
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional
Pssm-ID: 183063 [Multi-domain] Cd Length: 250 Bit Score: 57.07 E-value: 8.16e-10
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446512897 1 MIKIENLTKSYRTPTgrhyVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKI 62
Cdd:PRK11264 3 AIEVKNLVKKFHGQT----VLHGIDLEVKPGEVVAIIGPSGSGKTTLLRCINLLEQPEAGTI 60
|
|
| PRK09700 |
PRK09700 |
D-allose ABC transporter ATP-binding protein AlsA; |
1-198 |
8.87e-10 |
|
D-allose ABC transporter ATP-binding protein AlsA;
Pssm-ID: 182036 [Multi-domain] Cd Length: 510 Bit Score: 57.87 E-value: 8.87e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 1 MIKIENLTKSYrtptGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKIITNKT--------ISWPV 72
Cdd:PRK09700 5 YISMAGIGKSF----GPVHALKSVNLTVYPGEIHALLGENGAGKSTLMKVLSGIHEPTKGTITINNInynkldhkLAAQL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 73 GLAGGFQ-----GSLTGRENVkFVARLYAKQ---------EELKEKIEFVEEFAELGKYFDMPIKTYSSGMRSRLGFGLS 138
Cdd:PRK09700 81 GIGIIYQelsviDELTVLENL-YIGRHLTKKvcgvniidwREMRVRAAMMLLRVGLKVDLDEKVANLSISHKQMLEIAKT 159
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446512897 139 MAFKFDYYIVDEVTAvgdARFKEKCAQLF----KERHKESSFLMVSHSLNSLKEFCDVAIVFKN 198
Cdd:PRK09700 160 LMLDAKVIIMDEPTS---SLTNKEVDYLFlimnQLRKEGTAIVYISHKLAEIRRICDRYTVMKD 220
|
|
| cbiO |
PRK13640 |
energy-coupling factor transporter ATPase; |
2-202 |
8.91e-10 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184200 [Multi-domain] Cd Length: 282 Bit Score: 57.12 E-value: 8.91e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 2 IKIENLTKSYrtPTGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDS---------GKIITNKTIsWPV 72
Cdd:PRK13640 6 VEFKHVSFTY--PDSKKPALNDISFSIPRGSWTALIGHNGSGKSTISKLINGLLLPDDnpnskitvdGITLTAKTV-WDI 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 73 GLAGG---------FQGSLTGrENVKFvaRLYAKQEELKEKIEFVEE-FAELG--KYFDMPIKTYSSGMRSRLGFGLSMA 140
Cdd:PRK13640 83 REKVGivfqnpdnqFVGATVG-DDVAF--GLENRAVPRPEMIKIVRDvLADVGmlDYIDSEPANLSGGQKQRVAIAGILA 159
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446512897 141 FKFDYYIVDEVTAVGDARFKEKCAQLFKERHKESSFLMVS--HSLNSlKEFCDVAIVFKNSYII 202
Cdd:PRK13640 160 VEPKIIILDESTSMLDPAGKEQILKLIRKLKKKNNLTVISitHDIDE-ANMADQVLVLDDGKLL 222
|
|
| PRK15112 |
PRK15112 |
peptide ABC transporter ATP-binding protein SapF; |
1-65 |
9.63e-10 |
|
peptide ABC transporter ATP-binding protein SapF;
Pssm-ID: 185067 [Multi-domain] Cd Length: 267 Bit Score: 57.11 E-value: 9.63e-10
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 1 MIKIENLTKSYRTPTG---RHYV--FKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKIITN 65
Cdd:PRK15112 4 LLEVRNLSKTFRYRTGwfrRQTVeaVKPLSFTLREGQTLAIIGENGSGKSTLAKMLAGMIEPTSGELLID 73
|
|
| ModF |
COG1119 |
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA ... |
1-133 |
1.07e-09 |
|
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA [Inorganic ion transport and metabolism];
Pssm-ID: 440736 [Multi-domain] Cd Length: 250 Bit Score: 56.63 E-value: 1.07e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 1 MIKIENLTKSYrtptGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKIIT---NKTISWPV----- 72
Cdd:COG1119 3 LLELRNVTVRR----GGKTILDDISWTVKPGEHWAILGPNGAGKSTLLSLITGDLPPTYGNDVRlfgERRGGEDVwelrk 78
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446512897 73 -------GLAGGFQGSLTGRENV---KF-VARLYAK-QEELKEKIEFVEEFAELGKYFDMPIKTYSSGMRSRL 133
Cdd:COG1119 79 riglvspALQLRFPRDETVLDVVlsgFFdSIGLYREpTDEQRERARELLELLGLAHLADRPFGTLSQGEQRRV 151
|
|
| PRK15056 |
PRK15056 |
manganese/iron ABC transporter ATP-binding protein; |
2-199 |
1.12e-09 |
|
manganese/iron ABC transporter ATP-binding protein;
Pssm-ID: 185016 [Multi-domain] Cd Length: 272 Bit Score: 56.81 E-value: 1.12e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 2 IKIENLTKSYRTPtgrHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKII-----TNKTI-------- 68
Cdd:PRK15056 7 IVVNDVTVTWRNG---HTALRDASFTVPGGSIAALVGVNGSGKSTLFKALMGFVRLASGKISilgqpTRQALqknlvayv 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 69 --------SWPVGLaggfqgsltgrENVKFVAR------LYAKQEELKEKIEFVEEFAELGKYFDMPIKTYSSGMRSRLG 134
Cdd:PRK15056 84 pqseevdwSFPVLV-----------EDVVMMGRyghmgwLRRAKKRDRQIVTAALARVDMVEFRHRQIGELSGGQKKRVF 152
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446512897 135 FGLSMAFKFDYYIVDEVTAVGDARFKEKCAQLFKERHKESSFLMVS-HSLNSLKEFCDVAIVFKNS 199
Cdd:PRK15056 153 LARAIAQQGQVILLDEPFTGVDVKTEARIISLLRELRDEGKTMLVStHNLGSVTEFCDYTVMVKGT 218
|
|
| cbiO |
PRK13646 |
energy-coupling factor transporter ATPase; |
2-202 |
1.28e-09 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184205 [Multi-domain] Cd Length: 286 Bit Score: 56.71 E-value: 1.28e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 2 IKIENLTKSYRTPTGRHYV-FKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKI------ITNKT------- 67
Cdd:PRK13646 3 IRFDNVSYTYQKGTPYEHQaIHDVNTEFEQGKYYAIVGQTGSGKSTLIQNINALLKPTTGTVtvdditITHKTkdkyirp 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 68 ISWPVGLAGGFQGSLTGRENVKFVARLYAKQeeLKEKIEFVEEFA-----ELGKYFDM----PIKTYSSGMRsRLGFGLS 138
Cdd:PRK13646 83 VRKRIGMVFQFPESQLFEDTVEREIIFGPKN--FKMNLDEVKNYAhrllmDLGFSRDVmsqsPFQMSGGQMR-KIAIVSI 159
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446512897 139 MAFKFDYYIVDEVTAVGDARFKEKCAQLFKERHKES--SFLMVSHSLNSLKEFCDVAIVFKNSYII 202
Cdd:PRK13646 160 LAMNPDIIVLDEPTAGLDPQSKRQVMRLLKSLQTDEnkTIILVSHDMNEVARYADEVIVMKEGSIV 225
|
|
| ABC_MTABC3_MDL1_MDL2 |
cd03249 |
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 ... |
2-202 |
1.57e-09 |
|
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 (also known as ABCB6) is a mitochondrial ATP-binding cassette protein involved in iron homeostasis and one of four ABC transporters expressed in the mitochondrial inner membrane, the other three being MDL1(ABC7), MDL2, and ATM1. In fact, the yeast MDL1 (multidrug resistance-like protein 1) and MDL2 (multidrug resistance-like protein 2) transporters are also included in this CD. MDL1 is an ATP-dependent permease that acts as a high-copy suppressor of ATM1 and is thought to have a role in resistance to oxidative stress. Interestingly, subfamily B is more closely related to the carboxyl-terminal component of subfamily C than the two halves of ABCC molecules are with one another.
Pssm-ID: 213216 [Multi-domain] Cd Length: 238 Bit Score: 56.01 E-value: 1.57e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 2 IKIENLTKSYRT-PTgrHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKI------ITNKTISW---P 71
Cdd:cd03249 1 IEFKNVSFRYPSrPD--VPILKGLSLTIPPGKTVALVGSSGCGKSTVVSLLERFYDPTSGEIlldgvdIRDLNLRWlrsQ 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 72 VGLAGG----FQGSLtgRENVKFvARLYAKQEELKEKIEFVE--EF-AELGKYFDMPI----KTYSSGMRSRLGFGLSMA 140
Cdd:cd03249 79 IGLVSQepvlFDGTI--AENIRY-GKPDATDEEVEEAAKKANihDFiMSLPDGYDTLVgergSQLSGGQKQRIAIARALL 155
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446512897 141 FKFDYYIVDEVTAVGDARFKEKCAQLFKERHKESSFLMVSHSLNSLKEfCDVAIVFKNSYII 202
Cdd:cd03249 156 RNPKILLLDEATSALDAESEKLVQEALDRAMKGRTTIVIAHRLSTIRN-ADLIAVLQNGQVV 216
|
|
| lolD |
PRK11629 |
lipoprotein-releasing ABC transporter ATP-binding protein LolD; |
6-63 |
2.34e-09 |
|
lipoprotein-releasing ABC transporter ATP-binding protein LolD;
Pssm-ID: 183244 [Multi-domain] Cd Length: 233 Bit Score: 55.59 E-value: 2.34e-09
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 446512897 6 NLTKSYRTPTGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKII 63
Cdd:PRK11629 10 NLCKRYQEGSVQTDVLHNVSFSIGEGEMMAIVGSSGSGKSTLLHLLGGLDTPTSGDVI 67
|
|
| potA |
PRK09452 |
spermidine/putrescine ABC transporter ATP-binding protein PotA; |
2-65 |
3.15e-09 |
|
spermidine/putrescine ABC transporter ATP-binding protein PotA;
Pssm-ID: 236523 [Multi-domain] Cd Length: 375 Bit Score: 56.11 E-value: 3.15e-09
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446512897 2 IKIENLTKSYrtptGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKIITN 65
Cdd:PRK09452 15 VELRGISKSF----DGKEVISNLDLTINNGEFLTLLGPSGCGKTTVLRLIAGFETPDSGRIMLD 74
|
|
| ABCC_TAP |
cd03248 |
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; ... |
2-187 |
3.62e-09 |
|
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; TAP (Transporter Associated with Antigen Processing) is essential for peptide delivery from the cytosol into the lumen of the endoplasmic reticulum (ER), where these peptides are loaded on major histocompatibility complex (MHC) I molecules. Loaded MHC I leave the ER and display their antigenic cargo on the cell surface to cytotoxic T cells. Subsequently, virus-infected or malignantly transformed cells can be eliminated. TAP belongs to the large family of ATP-binding cassette (ABC) transporters, which translocate a vast variety of solutes across membranes.
Pssm-ID: 213215 [Multi-domain] Cd Length: 226 Bit Score: 54.78 E-value: 3.62e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 2 IKIENLTKSYRTPTGrHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKIITN-KTISWPVGLAGGFQG 80
Cdd:cd03248 12 VKFQNVTFAYPTRPD-TLVLQDVSFTLHPGEVTALVGPSGSGKSTVVALLENFYQPQGGQVLLDgKPISQYEHKYLHSKV 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 81 SLTGRENVKFVARL-----YAKQEELKEKI----------EFVEEFaELGKYFDMPIK--TYSSGMRSRLGFGLSMAFKF 143
Cdd:cd03248 91 SLVGQEPVLFARSLqdniaYGLQSCSFECVkeaaqkahahSFISEL-ASGYDTEVGEKgsQLSGGQKQRVAIARALIRNP 169
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 446512897 144 DYYIVDEVTAVGDARFKEKCAQLFKERHKESSFLMVSHSLNSLK 187
Cdd:cd03248 170 QVLILDEATSALDAESEQQVQQALYDWPERRTVLVIAHRLSTVE 213
|
|
| PRK13633 |
PRK13633 |
energy-coupling factor transporter ATPase; |
1-174 |
3.66e-09 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237453 [Multi-domain] Cd Length: 280 Bit Score: 55.48 E-value: 3.66e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 1 MIKIENLTKSYR--TPTGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKII------TNKTISWPV 72
Cdd:PRK13633 4 MIKCKNVSYKYEsnEESTEKLALDDVNLEVKKGEFLVILGRNGSGKSTIAKHMNALLIPSEGKVYvdgldtSDEENLWDI 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 73 GLAGG--FQG------SLTGRENVKF-VARLYAKQEELKEKIEFVEEFAELGKYFDMPIKTYSSGMRSRLGFGLSMAFKF 143
Cdd:PRK13633 84 RNKAGmvFQNpdnqivATIVEEDVAFgPENLGIPPEEIRERVDESLKKVGMYEYRRHAPHLLSGGQKQRVAIAGILAMRP 163
|
170 180 190
....*....|....*....|....*....|.
gi 446512897 144 DYYIVDEVTAVGDARFKEKCAQLFKERHKES 174
Cdd:PRK13633 164 ECIIFDEPTAMLDPSGRREVVNTIKELNKKY 194
|
|
| cbiO |
PRK13635 |
energy-coupling factor ABC transporter ATP-binding protein; |
2-62 |
4.77e-09 |
|
energy-coupling factor ABC transporter ATP-binding protein;
Pssm-ID: 184195 [Multi-domain] Cd Length: 279 Bit Score: 55.02 E-value: 4.77e-09
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446512897 2 IKIENLtkSYRTPTGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKI 62
Cdd:PRK13635 6 IRVEHI--SFRYPDAATYALKDVSFSVYEGEWVAIVGHNGSGKSTLAKLLNGLLLPEAGTI 64
|
|
| YddA |
COG4178 |
ABC-type uncharacterized transport system, permease and ATPase components [General function ... |
1-62 |
6.07e-09 |
|
ABC-type uncharacterized transport system, permease and ATPase components [General function prediction only];
Pssm-ID: 443337 [Multi-domain] Cd Length: 571 Bit Score: 55.20 E-value: 6.07e-09
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 1 MIKIENLTksYRTPTGRHyVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGG--------IDRPDSGKI 62
Cdd:COG4178 362 ALALEDLT--LRTPDGRP-LLEDLSLSLKPGERLLITGPSGSGKSTLLRAIAGlwpygsgrIARPAGARV 428
|
|
| cbiO |
PRK13639 |
cobalt transporter ATP-binding subunit; Provisional |
1-203 |
6.43e-09 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184199 [Multi-domain] Cd Length: 275 Bit Score: 54.70 E-value: 6.43e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 1 MIKIENLtkSYRTPTGRHyVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKI-ITNKTISW--------- 70
Cdd:PRK13639 1 ILETRDL--KYSYPDGTE-ALKGINFKAEKGEMVALLGPNGAGKSTLFLHFNGILKPTSGEVlIKGEPIKYdkksllevr 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 71 -PVGLAggFQG------SLTGRENVKF-VARLYAKQEELKEKIEFVEEFAELGKYFDMPIKTYSSGMRSRLGFGLSMAFK 142
Cdd:PRK13639 78 kTVGIV--FQNpddqlfAPTVEEDVAFgPLNLGLSKEEVEKRVKEALKAVGMEGFENKPPHHLSGGQKKRVAIAGILAMK 155
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446512897 143 FDYYIVDEVTAVGDARFKEKCAQLFKERHKESSFLMVS-HSLNSLKEFCDVAIVFKNSYIIG 203
Cdd:PRK13639 156 PEIIVLDEPTSGLDPMGASQIMKLLYDLNKEGITIIIStHDVDLVPVYADKVYVMSDGKIIK 217
|
|
| ABCC_ATM1_transporter |
cd03253 |
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC ... |
2-62 |
6.51e-09 |
|
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC transporter that is expressed in the mitochondria. Although the specific function of ATM1 is unknown, its disruption results in the accumulation of excess mitochondrial iron, loss of mitochondrial cytochromes, oxidative damage to mitochondrial DNA, and decreased levels of cytosolic heme proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213220 [Multi-domain] Cd Length: 236 Bit Score: 54.16 E-value: 6.51e-09
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446512897 2 IKIENLTKSYrtPTGRHyVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKI 62
Cdd:cd03253 1 IEFENVTFAY--DPGRP-VLKDVSFTIPAGKKVAIVGPSGSGKSTILRLLFRFYDVSSGSI 58
|
|
| PRK14267 |
PRK14267 |
phosphate ABC transporter ATP-binding protein; Provisional |
2-182 |
6.55e-09 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 184596 [Multi-domain] Cd Length: 253 Bit Score: 54.46 E-value: 6.55e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 2 IKIENLTKSYrtptGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGG-IDRPDSGKI-----ITNKTISWP---- 71
Cdd:PRK14267 5 IETVNLRVYY----GSNHVIKGVDLKIPQNGVFALMGPSGCGKSTLLRTFNRlLELNEEARVegevrLFGRNIYSPdvdp 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 72 ------VGLAggFQ-----GSLTGRENVKF---VARLYAKQEELKEKIEFVEEFAELGKYFDMPIKTY----SSGMRSRL 133
Cdd:PRK14267 81 ievrreVGMV--FQypnpfPHLTIYDNVAIgvkLNGLVKSKKELDERVEWALKKAALWDEVKDRLNDYpsnlSGGQRQRL 158
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 446512897 134 GFGLSMAFKFDYYIVDEVTAVGDARFKEKCAQLFKERHKESSFLMVSHS 182
Cdd:PRK14267 159 VIARALAMKPKILLMDEPTANIDPVGTAKIEELLFELKKEYTIVLVTHS 207
|
|
| glnQ |
PRK09493 |
glutamine ABC transporter ATP-binding protein GlnQ; |
1-63 |
8.39e-09 |
|
glutamine ABC transporter ATP-binding protein GlnQ;
Pssm-ID: 181906 [Multi-domain] Cd Length: 240 Bit Score: 53.94 E-value: 8.39e-09
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446512897 1 MIKIENLTKSYrtptGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKII 63
Cdd:PRK09493 1 MIEFKNVSKHF----GPTQVLHNIDLNIDQGEVVVIIGPSGSGKSTLLRCINKLEEITSGDLI 59
|
|
| artP |
PRK11124 |
arginine transporter ATP-binding subunit; Provisional |
2-65 |
1.44e-08 |
|
arginine transporter ATP-binding subunit; Provisional
Pssm-ID: 182980 [Multi-domain] Cd Length: 242 Bit Score: 53.48 E-value: 1.44e-08
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446512897 2 IKIENLTKSYrtptGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKI-ITN 65
Cdd:PRK11124 3 IQLNGINCFY----GAHQALFDITLDCPQGETLVLLGPSGAGKSSLLRVLNLLEMPRSGTLnIAG 63
|
|
| PRK10790 |
PRK10790 |
SmdB family multidrug efflux ABC transporter permease/ATP-binding protein; |
2-188 |
1.66e-08 |
|
SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;
Pssm-ID: 182733 [Multi-domain] Cd Length: 592 Bit Score: 53.95 E-value: 1.66e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 2 IKIENLTKSYRTptgRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKI-ITNKTISW---------- 70
Cdd:PRK10790 341 IDIDNVSFAYRD---DNLVLQNINLSVPSRGFVALVGHTGSGKSTLASLLMGYYPLTEGEIrLDGRPLSSlshsvlrqgv 417
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 71 ------PVGLAGGFQGSLT-GREnvkfvarlyAKQEELKEKIEFVeEFAELgkyfdmpIKTYSSGMRSRLG-------FG 136
Cdd:PRK10790 418 amvqqdPVVLADTFLANVTlGRD---------ISEEQVWQALETV-QLAEL-------ARSLPDGLYTPLGeqgnnlsVG 480
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 137 ----LSMA----FKFDYYIVDEVTAVGDARFKEKCAQLFKERHKESSFLMVSHSLNSLKE 188
Cdd:PRK10790 481 qkqlLALArvlvQTPQILILDEATANIDSGTEQAIQQALAAVREHTTLVVIAHRLSTIVE 540
|
|
| PstB |
COG1117 |
ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism]; ... |
2-49 |
1.69e-08 |
|
ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440734 [Multi-domain] Cd Length: 258 Bit Score: 53.12 E-value: 1.69e-08
10 20 30 40
....*....|....*....|....*....|....*....|....*...
gi 446512897 2 IKIENLTKSYrtptGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLR 49
Cdd:COG1117 12 IEVRNLNVYY----GDKQALKDINLDIPENKVTALIGPSGCGKSTLLR 55
|
|
| PRK10908 |
PRK10908 |
cell division ATP-binding protein FtsE; |
1-200 |
2.39e-08 |
|
cell division ATP-binding protein FtsE;
Pssm-ID: 182829 [Multi-domain] Cd Length: 222 Bit Score: 52.57 E-value: 2.39e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 1 MIKIENLTKSYrtpTGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKIitnktiswpvgLAGGFQG 80
Cdd:PRK10908 1 MIRFEHVSKAY---LGGRQALQGVTFHMRPGEMAFLTGHSGAGKSTLLKLICGIERPSAGKI-----------WFSGHDI 66
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 81 SLTGRENVKFVAR----------------LY-----------AKQEELKEKIE-FVEEFAELGKYFDMPIKtYSSGMRSR 132
Cdd:PRK10908 67 TRLKNREVPFLRRqigmifqdhhllmdrtVYdnvaipliiagASGDDIRRRVSaALDKVGLLDKAKNFPIQ-LSGGEQQR 145
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446512897 133 LGFGLSMAFKFDYYIVDEVTAVGDARFKEKCAQLFKERHKES-SFLMVSHslnslkefcDVAIVFKNSY 200
Cdd:PRK10908 146 VGIARAVVNKPAVLLADEPTGNLDDALSEGILRLFEEFNRVGvTVLMATH---------DIGLISRRSY 205
|
|
| rim_protein |
TIGR01257 |
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ... |
4-210 |
2.86e-08 |
|
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]
Pssm-ID: 130324 [Multi-domain] Cd Length: 2272 Bit Score: 53.48 E-value: 2.86e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 4 IENLTKSYRtPTGRHYVFKdLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKII-------TN-KTISWPVGLA 75
Cdd:TIGR01257 931 VKNLVKIFE-PSGRPAVDR-LNITFYENQITAFLGHNGAGKTTTLSILTGLLPPTSGTVLvggkdieTNlDAVRQSLGMC 1008
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 76 GGFQ---GSLTGRENVKFVARLYAK-QEELKEKIEFVEEFAELGKYFDMPIKTYSSGMRSRLGFGLSMAFKFDYYIVDEV 151
Cdd:TIGR01257 1009 PQHNilfHHLTVAEHILFYAQLKGRsWEEAQLEMEAMLEDTGLHHKRNEEAQDLSGGMQRKLSVAIAFVGDAKVVVLDEP 1088
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 152 TAVGDARFKEKCAQLFKERHKESSFLMVSHSLNSLKEFCD-VAIV-------------FKNSYIIGYY-------ENVQS 210
Cdd:TIGR01257 1089 TSGVDPYSRRSIWDLLLKYRSGRTIIMSTHHMDEADLLGDrIAIIsqgrlycsgtplfLKNCFGTGFYltlvrkmKNIQS 1168
|
|
| ABC2_perm_RbbA |
NF033858 |
ribosome-associated ATPase/putative transporter RbbA; |
2-95 |
4.32e-08 |
|
ribosome-associated ATPase/putative transporter RbbA;
Pssm-ID: 468210 [Multi-domain] Cd Length: 907 Bit Score: 52.82 E-value: 4.32e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 2 IKIENLTKSYrtptGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKI------ITNKT-------- 67
Cdd:NF033858 2 ARLEGVSHRY----GKTVALDDVSLDIPAGCMVGLIGPDGVGKSSLLSLIAGARKIQQGRVevlggdMADARhrravcpr 77
|
90 100
....*....|....*....|....*....
gi 446512897 68 ISW-PVGLAGGFQGSLTGRENVKFVARLY 95
Cdd:NF033858 78 IAYmPQGLGKNLYPTLSVFENLDFFGRLF 106
|
|
| NupO |
COG3845 |
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ... |
1-63 |
4.88e-08 |
|
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];
Pssm-ID: 443055 [Multi-domain] Cd Length: 504 Bit Score: 52.72 E-value: 4.88e-08
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446512897 1 MIKIENLTKSYrtptGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKII 63
Cdd:COG3845 5 ALELRGITKRF----GGVVANDDVSLTVRPGEIHALLGENGAGKSTLMKILYGLYQPDSGEIL 63
|
|
| cbiO |
PRK13650 |
energy-coupling factor transporter ATPase; |
1-198 |
5.16e-08 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184209 [Multi-domain] Cd Length: 279 Bit Score: 52.04 E-value: 5.16e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 1 MIKIENLTKSYRTPTgRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKII------TNKTIsWPVGL 74
Cdd:PRK13650 4 IIEVKNLTFKYKEDQ-EKYTLNDVSFHVKQGEWLSIIGHNGSGKSTTVRLIDGLLEAESGQIIidgdllTEENV-WDIRH 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 75 AGG--FQG------SLTGRENVKFvaRLYAKQEELKEKIEFVEEFAELGKYFDMPIKT---YSSGMRSRLGFGLSMAFKF 143
Cdd:PRK13650 82 KIGmvFQNpdnqfvGATVEDDVAF--GLENKGIPHEEMKERVNEALELVGMQDFKEREparLSGGQKQRVAIAGAVAMRP 159
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 446512897 144 DYYIVDEVTAVGDARFKEKCAQLFKERHKESSFLMVS--HSLNSLKeFCDVAIVFKN 198
Cdd:PRK13650 160 KIIILDEATSMLDPEGRLELIKTIKGIRDDYQMTVISitHDLDEVA-LSDRVLVMKN 215
|
|
| ABC_ABC_ChvD |
TIGR03719 |
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ... |
6-119 |
5.48e-08 |
|
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.
Pssm-ID: 274744 [Multi-domain] Cd Length: 552 Bit Score: 52.63 E-value: 5.48e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 6 NLTKSYrtPTGRHyVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKIITNKTISwpVG-LAGGFQ--GSL 82
Cdd:TIGR03719 9 RVSKVV--PPKKE-ILKDISLSFFPGAKIGVLGLNGAGKSTLLRIMAGVDKDFNGEARPQPGIK--VGyLPQEPQldPTK 83
|
90 100 110
....*....|....*....|....*....|....*....
gi 446512897 83 TGRENVKF-VARLYAKQEELKE-KIEFVEEFAELGKYFD 119
Cdd:TIGR03719 84 TVRENVEEgVAEIKDALDRFNEiSAKYAEPDADFDKLAA 122
|
|
| ABC_ThiQ_thiamine_transporter |
cd03298 |
ATP-binding cassette domain of the thiamine transport system; Part of the ... |
23-202 |
5.86e-08 |
|
ATP-binding cassette domain of the thiamine transport system; Part of the binding-protein-dependent transport system tbpA-thiPQ for thiamine and TPP. Probably responsible for the translocation of thiamine across the membrane. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213265 [Multi-domain] Cd Length: 211 Bit Score: 51.34 E-value: 5.86e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 23 DLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKIITNKT-------ISWPVGLAggFQ-----GSLTGRENVKF 90
Cdd:cd03298 16 HFDLTFAQGEITAIVGPSGSGKSTLLNLIAGFETPQSGRVLINGVdvtaappADRPVSML--FQennlfAHLTVEQNVGL 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 91 VA----RLYAKQEELKEKIEFVEEFAELGKyfDMPiKTYSSGMRSRLGFGLSMAFKFDYYIVDEVTAVGDARFKEKCAQL 166
Cdd:cd03298 94 GLspglKLTAEDRQAIEVALARVGLAGLEK--RLP-GELSGGERQRVALARVLVRDKPVLLLDEPFAALDPALRAEMLDL 170
|
170 180 190
....*....|....*....|....*....|....*...
gi 446512897 167 FKERHKES--SFLMVSHSLNSLKEFCDVAIVFKNSYII 202
Cdd:cd03298 171 VLDLHAETkmTVLMVTHQPEDAKRLAQRVVFLDNGRIA 208
|
|
| PRK10535 |
PRK10535 |
macrolide ABC transporter ATP-binding protein/permease MacB; |
1-60 |
6.98e-08 |
|
macrolide ABC transporter ATP-binding protein/permease MacB;
Pssm-ID: 182528 [Multi-domain] Cd Length: 648 Bit Score: 52.42 E-value: 6.98e-08
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 1 MIKIENLTKSYRTPTGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSG 60
Cdd:PRK10535 4 LLELKDIRRSYPSGEEQVEVLKGISLDIYAGEMVAIVGASGSGKSTLMNILGCLDKPTSG 63
|
|
| PRK13651 |
PRK13651 |
cobalt transporter ATP-binding subunit; Provisional |
2-202 |
8.87e-08 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184210 [Multi-domain] Cd Length: 305 Bit Score: 51.63 E-value: 8.87e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 2 IKIENLTKSYRTPTGRHY-VFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKII-------TNKTISWPVG 73
Cdd:PRK13651 3 IKVKNIVKIFNKKLPTELkALDNVSVEINQGEFIAIIGQTGSGKTTFIEHLNALLLPDTGTIEwifkdekNKKKTKEKEK 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 74 LAGGFQGSLTGRENVKFVarlyakqEELKEKIEFVEEFAE------------------LG-----------KYFDM---P 121
Cdd:PRK13651 83 VLEKLVIQKTRFKKIKKI-------KEIRRRVGVVFQFAEyqlfeqtiekdiifgpvsMGvskeeakkraaKYIELvglD 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 122 IK-------TYSSGMRSRLGFGLSMAFKFDYYIVDEVTAVGDARFKEKCAQLFKERHKE-SSFLMVSHSLNSLKEFCDVA 193
Cdd:PRK13651 156 ESylqrspfELSGGQKRRVALAGILAMEPDFLVFDEPTAGLDPQGVKEILEIFDNLNKQgKTIILVTHDLDNVLEWTKRT 235
|
....*....
gi 446512897 194 IVFKNSYII 202
Cdd:PRK13651 236 IFFKDGKII 244
|
|
| thiQ |
PRK10771 |
thiamine ABC transporter ATP-binding protein ThiQ; |
1-65 |
9.36e-08 |
|
thiamine ABC transporter ATP-binding protein ThiQ;
Pssm-ID: 182716 [Multi-domain] Cd Length: 232 Bit Score: 50.74 E-value: 9.36e-08
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446512897 1 MIKIENLTKSYRTPTGRhyvFkDLNIEipSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKIITN 65
Cdd:PRK10771 1 MLKLTDITWLYHHLPMR---F-DLTVE--RGERVAILGPSGAGKSTLLNLIAGFLTPASGSLTLN 59
|
|
| znuC |
PRK09544 |
high-affinity zinc transporter ATPase; Reviewed |
1-62 |
1.13e-07 |
|
high-affinity zinc transporter ATPase; Reviewed
Pssm-ID: 181939 [Multi-domain] Cd Length: 251 Bit Score: 50.88 E-value: 1.13e-07
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446512897 1 MIKIENLTKSYrtptGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKI 62
Cdd:PRK09544 4 LVSLENVSVSF----GQRRVLSDVSLELKPGKILTLLGPNGAGKSTLVRVVLGLVAPDEGVI 61
|
|
| cbiO |
PRK13648 |
cobalt transporter ATP-binding subunit; Provisional |
1-183 |
1.31e-07 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184207 [Multi-domain] Cd Length: 269 Bit Score: 50.91 E-value: 1.31e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 1 MIKIENLTKSYRTPTGrhYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKIITN---------KTISWP 71
Cdd:PRK13648 7 IIVFKNVSFQYQSDAS--FTLKDVSFNIPKGQWTSIVGHNGSGKSTIAKLMIGIEKVKSGEIFYNnqaitddnfEKLRKH 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 72 VGLA-----GGFQGSLtgrenVKF-VARLYAKQ----EELKEKIEFVEEFAELGKYFDMPIKTYSSGMRSRLGFGLSMAF 141
Cdd:PRK13648 85 IGIVfqnpdNQFVGSI-----VKYdVAFGLENHavpyDEMHRRVSEALKQVDMLERADYEPNALSGGQKQRVAIAGVLAL 159
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 446512897 142 KFDYYIVDEVTAVGDARFKEKCAQLFKE--RHKESSFLMVSHSL 183
Cdd:PRK13648 160 NPSVIILDEATSMLDPDARQNLLDLVRKvkSEHNITIISITHDL 203
|
|
| cbiO |
PRK13652 |
cobalt transporter ATP-binding subunit; Provisional |
1-204 |
1.51e-07 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 172200 [Multi-domain] Cd Length: 277 Bit Score: 50.57 E-value: 1.51e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 1 MIKIENLTKSYRtptGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKI------ITNKTISWP--- 71
Cdd:PRK13652 3 LIETRDLCYSYS---GSKEALNNINFIAPRNSRIAVIGPNGAGKSTLFRHFNGILKPTSGSVlirgepITKENIREVrkf 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 72 VGLAggFQG------SLTGRENVKF-VARLYAKQEELKEKIEFVEEFAELGKYFDMPIKTYSSGMRSRLGFGLSMAFKFD 144
Cdd:PRK13652 80 VGLV--FQNpddqifSPTVEQDIAFgPINLGLDEETVAHRVSSALHMLGLEELRDRVPHHLSGGEKKRVAIAGVIAMEPQ 157
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446512897 145 YYIVDEVTAVGDARFKEKCAQLFKERHKESSFLMV--SHSLNSLKEFCDVAIVFKNSYIIGY 204
Cdd:PRK13652 158 VLVLDEPTAGLDPQGVKELIDFLNDLPETYGMTVIfsTHQLDLVPEMADYIYVMDKGRIVAY 219
|
|
| ABCC_Hemolysin |
cd03252 |
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a ... |
2-63 |
1.80e-07 |
|
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a central component of the secretion machinery that translocates the toxin, hemolysin A, in a Sec-independent fashion across both membranes of E. coli. The hemolysin A (HlyA) transport machinery is composed of the ATP-binding cassette (ABC) transporter HlyB located in the inner membrane, hemolysin D (HlyD), also anchored in the inner membrane, and TolC, which resides in the outer membrane. HlyD apparently forms a continuous channel that bridges the entire periplasm, interacting with TolC and HlyB. This arrangement prevents the appearance of periplasmic intermediates of HlyA during substrate transport. Little is known about the molecular details of HlyA transport, but it is evident that ATP-hydrolysis by the ABC-transporter HlyB is a necessary source of energy.
Pssm-ID: 213219 [Multi-domain] Cd Length: 237 Bit Score: 50.18 E-value: 1.80e-07
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446512897 2 IKIENLTKSYRtPTGRhYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKII 63
Cdd:cd03252 1 ITFEHVRFRYK-PDGP-VILDNISLRIKPGEVVGIVGRSGSGKSTLTKLIQRFYVPENGRVL 60
|
|
| PRK10895 |
PRK10895 |
lipopolysaccharide ABC transporter ATP-binding protein; Provisional |
5-65 |
2.58e-07 |
|
lipopolysaccharide ABC transporter ATP-binding protein; Provisional
Pssm-ID: 182817 [Multi-domain] Cd Length: 241 Bit Score: 49.89 E-value: 2.58e-07
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446512897 5 ENLTKSYRtptGRHyVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKIITN 65
Cdd:PRK10895 7 KNLAKAYK---GRR-VVEDVSLTVNSGEIVGLLGPNGAGKTTTFYMVVGIVPRDAGNIIID 63
|
|
| ABCC_MsbA |
cd03251 |
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; ... |
2-62 |
2.70e-07 |
|
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; MsbA is an essential ABC transporter, closely related to eukaryotic MDR proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213218 [Multi-domain] Cd Length: 234 Bit Score: 49.54 E-value: 2.70e-07
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446512897 2 IKIENLTKSYRtPTGRHyVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKI 62
Cdd:cd03251 1 VEFKNVTFRYP-GDGPP-VLRDISLDIPAGETVALVGPSGSGKSTLVNLIPRFYDVDSGRI 59
|
|
| PRK11176 |
PRK11176 |
lipid A ABC transporter ATP-binding protein/permease MsbA; |
2-63 |
3.09e-07 |
|
lipid A ABC transporter ATP-binding protein/permease MsbA;
Pssm-ID: 183016 [Multi-domain] Cd Length: 582 Bit Score: 50.40 E-value: 3.09e-07
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446512897 2 IKIENLTKSYrtPTGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKII 63
Cdd:PRK11176 342 IEFRNVTFTY--PGKEVPALRNINFKIPAGKTVALVGRSGSGKSTIANLLTRFYDIDEGEIL 401
|
|
| Rli1 |
COG1245 |
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ... |
2-153 |
3.36e-07 |
|
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];
Pssm-ID: 440858 [Multi-domain] Cd Length: 592 Bit Score: 50.17 E-value: 3.36e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 2 IKIENLTKSYRTptgrhyvFKdLNIE---IPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKIITNKTISW-PVGLAGG 77
Cdd:COG1245 342 VEYPDLTKSYGG-------FS-LEVEggeIREGEVLGIVGPNGIGKTTFAKILAGVLKPDEGEVDEDLKISYkPQYISPD 413
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 78 FQGSltgrenVKFVARlyakqEELKEKIE---FVEEFAE---LGKYFDMPIKTYSSGMRSRLGFGLSMAFKFDYYIVDEV 151
Cdd:COG1245 414 YDGT------VEEFLR-----SANTDDFGssyYKTEIIKplgLEKLLDKNVKDLSGGELQRVAIAACLSRDADLYLLDEP 482
|
..
gi 446512897 152 TA 153
Cdd:COG1245 483 SA 484
|
|
| btuD |
PRK09536 |
corrinoid ABC transporter ATPase; Reviewed |
1-201 |
3.67e-07 |
|
corrinoid ABC transporter ATPase; Reviewed
Pssm-ID: 236554 [Multi-domain] Cd Length: 402 Bit Score: 49.84 E-value: 3.67e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 1 MIKIENLTKSYrtptGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKI--------------ITNK 66
Cdd:PRK09536 3 MIDVSDLSVEF----GDTTVLDGVDLSVREGSLVGLVGPNGAGKTTLLRAINGTLTPTAGTVlvagddvealsaraASRR 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 67 TISWPVGLAGGFQgsLTGRENVKF-----VARLYAKQEELKEKIEFVEEFAELGKYFDMPIKTYSSGMRSRLGFGLSMAF 141
Cdd:PRK09536 79 VASVPQDTSLSFE--FDVRQVVEMgrtphRSRFDTWTETDRAAVERAMERTGVAQFADRPVTSLSGGERQRVLLARALAQ 156
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446512897 142 KFDYYIVDEVTAVGDARFKEKCAQLFKERHKESSFLMVS-HSLNSLKEFCDVAIVFKNSYI 201
Cdd:PRK09536 157 ATPVLLLDEPTASLDINHQVRTLELVRRLVDDGKTAVAAiHDLDLAARYCDELVLLADGRV 217
|
|
| PRK10575 |
PRK10575 |
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC; |
10-70 |
4.08e-07 |
|
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;
Pssm-ID: 182561 [Multi-domain] Cd Length: 265 Bit Score: 49.40 E-value: 4.08e-07
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446512897 10 SYRTPtGRhYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKIITNKTI--SW 70
Cdd:PRK10575 18 SFRVP-GR-TLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPleSW 78
|
|
| ABC_Pro_Gly_Betaine |
cd03294 |
ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This ... |
2-184 |
4.53e-07 |
|
ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This family comprises the glycine betaine/L-proline ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporters is the obligatory coupling of ATP hydrolysis to substrate translocation. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213261 [Multi-domain] Cd Length: 269 Bit Score: 49.18 E-value: 4.53e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 2 IKIENLTKSYRTPTGRHY-----------VFK---------DLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGK 61
Cdd:cd03294 1 IKIKGLYKIFGKNPQKAFkllakgkskeeILKktgqtvgvnDVSLDVREGEIFVIMGLSGSGKSTLLRCINRLIEPTSGK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 62 I-ITNKTISwpvGLAGG-------------FQG-----SLTGRENVKF------VARlyakqEELKEKIEFVEEFAELGK 116
Cdd:cd03294 81 VlIDGQDIA---AMSRKelrelrrkkismvFQSfallpHRTVLENVAFglevqgVPR-----AEREERAAEALELVGLEG 152
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446512897 117 YFDMPIKTYSSGMRSRLGFGLSMAFKFDYYIVDEVTAVGD----ARFKEKCAQLFKERHKESSFlmVSHSLN 184
Cdd:cd03294 153 WEHKYPDELSGGMQQRVGLARALAVDPDILLMDEAFSALDplirREMQDELLRLQAELQKTIVF--ITHDLD 222
|
|
| PTZ00265 |
PTZ00265 |
multidrug resistance protein (mdr1); Provisional |
20-67 |
4.80e-07 |
|
multidrug resistance protein (mdr1); Provisional
Pssm-ID: 240339 [Multi-domain] Cd Length: 1466 Bit Score: 50.03 E-value: 4.80e-07
10 20 30 40
....*....|....*....|....*....|....*....|....*...
gi 446512897 20 VFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKIITNKT 67
Cdd:PTZ00265 400 IYKDLNFTLTEGKTYAFVGESGCGKSTILKLIERLYDPTEGDIIINDS 447
|
|
| PRK11819 |
PRK11819 |
putative ABC transporter ATP-binding protein; Reviewed |
6-119 |
4.90e-07 |
|
putative ABC transporter ATP-binding protein; Reviewed
Pssm-ID: 236992 [Multi-domain] Cd Length: 556 Bit Score: 49.73 E-value: 4.90e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 6 NLTKSYrtPTGRHyVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKIITNKTISwpVG-LAggfQ----- 79
Cdd:PRK11819 11 RVSKVV--PPKKQ-ILKDISLSFFPGAKIGVLGLNGAGKSTLLRIMAGVDKEFEGEARPAPGIK--VGyLP---Qepqld 82
|
90 100 110 120
....*....|....*....|....*....|....*....|.
gi 446512897 80 GSLTGRENVKF-VARLYAKQEELKekiEFVEEFAELGKYFD 119
Cdd:PRK11819 83 PEKTVRENVEEgVAEVKAALDRFN---EIYAAYAEPDADFD 120
|
|
| araG |
PRK11288 |
L-arabinose ABC transporter ATP-binding protein AraG; |
23-197 |
6.90e-07 |
|
L-arabinose ABC transporter ATP-binding protein AraG;
Pssm-ID: 183077 [Multi-domain] Cd Length: 501 Bit Score: 49.14 E-value: 6.90e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 23 DLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKI--------ITNKTISWPVGLAGGFQG-----SLTGRENVk 89
Cdd:PRK11288 22 DISFDCRAGQVHALMGENGAGKSTLLKILSGNYQPDAGSIlidgqemrFASTTAALAAGVAIIYQElhlvpEMTVAENL- 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 90 FVARLYAK-----QEELKEkiEFVEEFAELGKYFD--MPIKTYSSGMRS--RLGFGLS-----MAFkfdyyivDEVTAVG 155
Cdd:PRK11288 101 YLGQLPHKggivnRRLLNY--EAREQLEHLGVDIDpdTPLKYLSIGQRQmvEIAKALArnarvIAF-------DEPTSSL 171
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 446512897 156 DARFKEkcaQLFKE----RHKESSFLMVSHSLNSLKEFCDVAIVFK 197
Cdd:PRK11288 172 SAREIE---QLFRVirelRAEGRVILYVSHRMEEIFALCDAITVFK 214
|
|
| 3a01208 |
TIGR00958 |
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other] |
20-197 |
1.27e-06 |
|
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273363 [Multi-domain] Cd Length: 711 Bit Score: 48.57 E-value: 1.27e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 20 VFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKI---------ITNKTISWPVGLAGG----FQGSLtgRE 86
Cdd:TIGR00958 496 VLKGLTFTLHPGEVVALVGPSGSGKSTVAALLQNLYQPTGGQVlldgvplvqYDHHYLHRQVALVGQepvlFSGSV--RE 573
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 87 NVKFVARLYAKQEELK-EKIEFVEEF-AELGKYFDMPIKTY----SSGMRSRLGFGLSMAFKFDYYIVDEVTAVGDARfk 160
Cdd:TIGR00958 574 NIAYGLTDTPDEEIMAaAKAANAHDFiMEFPNGYDTEVGEKgsqlSGGQKQRIAIARALVRKPRVLILDEATSALDAE-- 651
|
170 180 190
....*....|....*....|....*....|....*....
gi 446512897 161 ekCAQLFKE--RHKESSFLMVSHSLnSLKEFCDVAIVFK 197
Cdd:TIGR00958 652 --CEQLLQEsrSRASRTVLLIAHRL-STVERADQILVLK 687
|
|
| met_CoM_red_A2 |
TIGR03269 |
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ... |
1-202 |
1.57e-06 |
|
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]
Pssm-ID: 132313 [Multi-domain] Cd Length: 520 Bit Score: 48.26 E-value: 1.57e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 1 MIKIENLTKSY-RTPTGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKIITNKTISWPVGLAGGFQ 79
Cdd:TIGR03269 279 IIKVRNVSKRYiSVDRGVVKAVDNVSLEVKEGEIFGIVGTSGAGKTTLSKIIAGVLEPTSGEVNVRVGDEWVDMTKPGPD 358
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 80 GSLTGRENVKFVARLYAKQ------EELKEKI--EFVEEFAE--------------------LGKYFDmpikTYSSGMRS 131
Cdd:TIGR03269 359 GRGRAKRYIGILHQEYDLYphrtvlDNLTEAIglELPDELARmkavitlkmvgfdeekaeeiLDKYPD----ELSEGERH 434
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446512897 132 RLGFGLSMAFKFDYYIVDEVTAVGDARFKEKCAQ-LFKERHK-ESSFLMVSHSLNSLKEFCDVAIVFKNSYII 202
Cdd:TIGR03269 435 RVALAQVLIKEPRIVILDEPTGTMDPITKVDVTHsILKAREEmEQTFIIVSHDMDFVLDVCDRAALMRDGKIV 507
|
|
| modC |
PRK11144 |
molybdenum ABC transporter ATP-binding protein ModC; |
23-68 |
1.57e-06 |
|
molybdenum ABC transporter ATP-binding protein ModC;
Pssm-ID: 182993 [Multi-domain] Cd Length: 352 Bit Score: 47.95 E-value: 1.57e-06
10 20 30 40
....*....|....*....|....*....|....*....|....*.
gi 446512897 23 DLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKIITNKTI 68
Cdd:PRK11144 16 TVNLTLPAQGITAIFGRSGAGKTSLINAISGLTRPQKGRIVLNGRV 61
|
|
| rim_protein |
TIGR01257 |
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ... |
1-200 |
2.21e-06 |
|
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]
Pssm-ID: 130324 [Multi-domain] Cd Length: 2272 Bit Score: 48.09 E-value: 2.21e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 1 MIKIENLTKSYrtPTGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSG-------KIITN-KTISWPV 72
Cdd:TIGR01257 1937 ILRLNELTKVY--SGTSSPAVDRLCVGVRPGECFGLLGVNGAGKTTTFKMLTGDTTVTSGdatvagkSILTNiSDVHQNM 2014
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 73 GLAGGFQGS---LTGRENVKFVARLYA-KQEELKEKIEFVEEFAELGKYFDMPIKTYSSGMRSRLGFGLSMAFKFDYYIV 148
Cdd:TIGR01257 2015 GYCPQFDAIddlLTGREHLYLYARLRGvPAEEIEKVANWSIQSLGLSLYADRLAGTYSGGNKRKLSTAIALIGCPPLVLL 2094
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 446512897 149 DEVTAVGDARFKEKCAQLFKERHKES-SFLMVSHSLNSLKEFCD-VAIVFKNSY 200
Cdd:TIGR01257 2095 DEPTTGMDPQARRMLWNTIVSIIREGrAVVLTSHSMEECEALCTrLAIMVKGAF 2148
|
|
| PRK13543 |
PRK13543 |
heme ABC exporter ATP-binding protein CcmA; |
20-133 |
2.35e-06 |
|
heme ABC exporter ATP-binding protein CcmA;
Pssm-ID: 184129 [Multi-domain] Cd Length: 214 Bit Score: 46.77 E-value: 2.35e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 20 VFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKIITN----------KTISWpVGLAGGFQGSLTGRENVK 89
Cdd:PRK13543 26 VFGPLDFHVDAGEALLVQGDNGAGKTTLLRVLAGLLHVESGQIQIDgktatrgdrsRFMAY-LGHLPGLKADLSTLENLH 104
|
90 100 110 120
....*....|....*....|....*....|....*....|....
gi 446512897 90 FVARLYAKQEelKEKIEFVEEFAELGKYFDMPIKTYSSGMRSRL 133
Cdd:PRK13543 105 FLCGLHGRRA--KQMPGSALAIVGLAGYEDTLVRQLSAGQKKRL 146
|
|
| PRK10619 |
PRK10619 |
histidine ABC transporter ATP-binding protein HisP; |
2-65 |
2.85e-06 |
|
histidine ABC transporter ATP-binding protein HisP;
Pssm-ID: 182592 [Multi-domain] Cd Length: 257 Bit Score: 46.89 E-value: 2.85e-06
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446512897 2 IKIENLTKSYrtptGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKIITN 65
Cdd:PRK10619 6 LNVIDLHKRY----GEHEVLKGVSLQANAGDVISIIGSSGSGKSTFLRCINFLEKPSEGSIVVN 65
|
|
| ABCC_NFT1 |
cd03369 |
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type ... |
2-204 |
2.92e-06 |
|
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type transporter 1). NFT1 belongs to the MRP (multidrug resistance-associated protein) family of ABC transporters. Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213269 [Multi-domain] Cd Length: 207 Bit Score: 46.25 E-value: 2.92e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 2 IKIENLTKSYRTPTGRhyVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKI-ITNKTISW---------- 70
Cdd:cd03369 7 IEVENLSVRYAPDLPP--VLKNVSFKVKAGEKIGIVGRTGAGKSTLILALFRFLEAEEGKIeIDGIDISTipledlrssl 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 71 ------PVGLAGgfqgslTGRENVKfvarLYAKQEElkEKIEFVEEFAELGKYFdmpiktySSGMRSRLGFGLSMAFKFD 144
Cdd:cd03369 85 tiipqdPTLFSG------TIRSNLD----PFDEYSD--EEIYGALRVSEGGLNL-------SQGQRQLLCLARALLKRPR 145
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 145 YYIVDEVTAVGDARFKEKCAQLFKERHKESSFLMVSHSLNSLKEfCDVAIVFKNSYIIGY 204
Cdd:cd03369 146 VLVLDEATASIDYATDALIQKTIREEFTNSTILTIAHRLRTIID-YDKILVMDAGEVKEY 204
|
|
| PRK15439 |
PRK15439 |
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional |
20-120 |
3.17e-06 |
|
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
Pssm-ID: 185336 [Multi-domain] Cd Length: 510 Bit Score: 47.35 E-value: 3.17e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 20 VFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKIITNKTISWPVGLAGGFQ-------------GSLTGRE 86
Cdd:PRK15439 26 VLKGIDFTLHAGEVHALLGGNGAGKSTLMKIIAGIVPPDSGTLEIGGNPCARLTPAKAHQlgiylvpqepllfPNLSVKE 105
|
90 100 110
....*....|....*....|....*....|....
gi 446512897 87 NVKFvaRLyAKQEELKEKIEfvEEFAELGKYFDM 120
Cdd:PRK15439 106 NILF--GL-PKRQASMQKMK--QLLAALGCQLDL 134
|
|
| 3a01203 |
TIGR00954 |
Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, ... |
1-54 |
3.19e-06 |
|
Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]
Pssm-ID: 273360 [Multi-domain] Cd Length: 659 Bit Score: 47.44 E-value: 3.19e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....
gi 446512897 1 MIKIENLtkSYRTPTGRHYVfKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGI 54
Cdd:TIGR00954 451 GIKFENI--PLVTPNGDVLI-ESLSFEVPSGNNLLICGPNGCGKSSLFRILGEL 501
|
|
| ABC_RNaseL_inhibitor_domain2 |
cd03237 |
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ... |
27-196 |
3.47e-06 |
|
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity of more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.
Pssm-ID: 213204 [Multi-domain] Cd Length: 246 Bit Score: 46.63 E-value: 3.47e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 27 EIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKIIT-NKTISW-PVGLAGGFQGSLTgrenvkfvARLYAKQEELKEK 104
Cdd:cd03237 21 SISESEVIGILGPNGIGKTTFIKMLAGVLKPDEGDIEIeLDTVSYkPQYIKADYEGTVR--------DLLSSITKDFYTH 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 105 IEFVEEFA---ELGKYFDMPIKTYSSGMRSRLGFGLSMAFKFDYYIVDEVTAVGDARFKEKCAQLFKE--RHKESSFLMV 179
Cdd:cd03237 93 PYFKTEIAkplQIEQILDREVPELSGGELQRVAIAACLSKDADIYLLDEPSAYLDVEQRLMASKVIRRfaENNEKTAFVV 172
|
170
....*....|....*..
gi 446512897 180 SHSLNSLKEFCDVAIVF 196
Cdd:cd03237 173 EHDIIMIDYLADRLIVF 189
|
|
| hmuV |
PRK13547 |
heme ABC transporter ATP-binding protein; |
1-53 |
3.53e-06 |
|
heme ABC transporter ATP-binding protein;
Pssm-ID: 184132 [Multi-domain] Cd Length: 272 Bit Score: 46.74 E-value: 3.53e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 446512897 1 MIKIENLTKSYRTptgrHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGG 53
Cdd:PRK13547 1 MLTADHLHVARRH----RAILRDLSLRIEPGRVTALLGRNGAGKSTLLKALAG 49
|
|
| PRK13409 |
PRK13409 |
ribosome biogenesis/translation initiation ATPase RLI; |
21-215 |
3.75e-06 |
|
ribosome biogenesis/translation initiation ATPase RLI;
Pssm-ID: 184037 [Multi-domain] Cd Length: 590 Bit Score: 47.11 E-value: 3.75e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 21 FKDLNIEIPS-GKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKiiTNKTISWPVGLAgGFQGSltgrENVKFVARLYAKQ- 98
Cdd:PRK13409 88 FKLYGLPIPKeGKVTGILGPNGIGKTTAVKILSGELIPNLGD--YEEEPSWDEVLK-RFRGT----ELQNYFKKLYNGEi 160
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 99 --------------------EELKEKI-------EFVEEFaELGKYFDMPIKTYSSGMRSRLGFGLSMAFKFDYYIVDEV 151
Cdd:PRK13409 161 kvvhkpqyvdlipkvfkgkvRELLKKVdergkldEVVERL-GLENILDRDISELSGGELQRVAIAAALLRDADFYFFDEP 239
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446512897 152 TAVGDARFKEKCAQLFKERHKESSFLMVSHSLNSLKEFCD-VAIVF--KNSY-IIGYYENVQSGIDEY 215
Cdd:PRK13409 240 TSYLDIRQRLNVARLIRELAEGKYVLVVEHDLAVLDYLADnVHIAYgePGAYgVVSKPKGVRVGINEY 307
|
|
| ABCG_White |
cd03234 |
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ... |
20-152 |
5.89e-06 |
|
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ABC transporters homologous to the Drosophila white gene, which acts as a dimeric importer for eye pigment precursors. The eye pigmentation of Drosophila is developed from the synthesis and deposition in the cells of red pigments, which are synthesized from guanine, and brown pigments, which are synthesized from tryptophan. The pigment precursors are encoded by the white, brown, and scarlet genes, respectively. Evidence from genetic and biochemical studies suggest that the White and Brown proteins function as heterodimers to import guanine, while the White and Scarlet proteins function to import tryptophan. However, a recent study also suggests that White may be involved in the transport of a metabolite, such as 3-hydroxykynurenine, across intracellular membranes. Mammalian ABC transporters belonging to the White subfamily (ABCG1, ABCG5, and ABCG8) have been shown to be involved in the regulation of lipid-trafficking mechanisms in macrophages, hepatocytes, and intestinal mucosa cells. ABCG1 (ABC8), the human homolog of the Drosophila white gene is induced in monocyte-derived macrophages during cholesterol influx mediated by acetylated low-density lipoprotein. It is possible that human ABCG1 forms heterodimers with several heterologous partners.
Pssm-ID: 213201 [Multi-domain] Cd Length: 226 Bit Score: 45.72 E-value: 5.89e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 20 VFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPD---SGKIITN----KTISWPVGLAGGFQ-----GSLTGREN 87
Cdd:cd03234 22 ILNDVSLHVESGQVMAILGSSGSGKTTLLDAISGRVEGGgttSGQILFNgqprKPDQFQKCVAYVRQddillPGLTVRET 101
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446512897 88 VKFVARLyAKQEELKEKI-EFVEEFAELGKYFDMPI-----KTYSSGMRSRLGFGLSMAFKFDYYIVDEVT 152
Cdd:cd03234 102 LTYTAIL-RLPRKSSDAIrKKRVEDVLLRDLALTRIggnlvKGISGGERRRVSIAVQLLWDPKVLILDEPT 171
|
|
| phnK |
PRK11701 |
phosphonate C-P lyase system protein PhnK; Provisional |
1-63 |
6.15e-06 |
|
phosphonate C-P lyase system protein PhnK; Provisional
Pssm-ID: 183280 [Multi-domain] Cd Length: 258 Bit Score: 45.69 E-value: 6.15e-06
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446512897 1 MIKIENLTKSYrtptGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKII 63
Cdd:PRK11701 6 LLSVRGLTKLY----GPRKGCRDVSFDLYPGEVLGIVGESGSGKTTLLNALSARLAPDAGEVH 64
|
|
| cbiO |
PRK13645 |
energy-coupling factor transporter ATPase; |
2-202 |
6.38e-06 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184204 [Multi-domain] Cd Length: 289 Bit Score: 45.77 E-value: 6.38e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 2 IKIENLTKSY--RTPtgrhYVFKDLN---IEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKIITN----------- 65
Cdd:PRK13645 7 IILDNVSYTYakKTP----FEFKALNntsLTFKKNKVTCVIGTTGSGKSTMIQLTNGLIISETGQTIVGdyaipanlkki 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 66 ---KTISWPVGLAGGFQGSLTGRENV-KFVA-----------RLYAKQEELKEKIEFVEEFAELGKYfdmpikTYSSGMR 130
Cdd:PRK13645 83 kevKRLRKEIGLVFQFPEYQLFQETIeKDIAfgpvnlgenkqEAYKKVPELLKLVQLPEDYVKRSPF------ELSGGQK 156
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446512897 131 SRLGFGLSMAFKFDYYIVDEVTAVGDARFKEKCAQLFKERHKE--SSFLMVSHSLNSLKEFCDVAIVFKNSYII 202
Cdd:PRK13645 157 RRVALAGIIAMDGNTLVLDEPTGGLDPKGEEDFINLFERLNKEykKRIIMVTHNMDQVLRIADEVIVMHEGKVI 230
|
|
| ATM1 |
COG5265 |
ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components ... |
22-62 |
7.60e-06 |
|
ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444078 [Multi-domain] Cd Length: 605 Bit Score: 45.97 E-value: 7.60e-06
10 20 30 40
....*....|....*....|....*....|....*....|.
gi 446512897 22 KDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKI 62
Cdd:COG5265 375 KGVSFEVPAGKTVAIVGPSGAGKSTLARLLFRFYDVTSGRI 415
|
|
| PRK09984 |
PRK09984 |
phosphonate ABC transporter ATP-binding protein; |
1-59 |
7.97e-06 |
|
phosphonate ABC transporter ATP-binding protein;
Pssm-ID: 182182 [Multi-domain] Cd Length: 262 Bit Score: 45.39 E-value: 7.97e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 446512897 1 MIKIENLTKSYRTPTGRHYVfkDLNIEipSGKSVAFIGRNGAGKSTLLRMIGGIDRPDS 59
Cdd:PRK09984 4 IIRVEKLAKTFNQHQALHAV--DLNIH--HGEMVALLGPSGSGKSTLLRHLSGLITGDK 58
|
|
| CFTR_protein |
TIGR01271 |
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ... |
11-149 |
9.19e-06 |
|
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]
Pssm-ID: 273530 [Multi-domain] Cd Length: 1490 Bit Score: 46.06 E-value: 9.19e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 11 YRTPtgrhyVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKIITNKTISWPVGLAGGFQGSLtgRENV-- 88
Cdd:TIGR01271 437 YVTP-----VLKNISFKLEKGQLLAVAGSTGSGKSSLLMMIMGELEPSEGKIKHSGRISFSPQTSWIMPGTI--KDNIif 509
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446512897 89 -----KFVARLYAKQEELKEKIEFveeFAELGKYFDMPIK-TYSSGMRSRLGFGLSMAFKFDYYIVD 149
Cdd:TIGR01271 510 glsydEYRYTSVIKACQLEEDIAL---FPEKDKTVLGEGGiTLSGGQRARISLARAVYKDADLYLLD 573
|
|
| ABC_FeS_Assembly |
cd03217 |
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of ... |
2-63 |
9.40e-06 |
|
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of iron-sulfur clusters (Fe-S) depends on multi-protein systems. The SUF system of E. coli and Erwinia chrysanthemi is important for Fe-S biogenesis under stressful conditions. The SUF system is made of six proteins: SufC is an atypical cytoplasmic ABC-ATPase, which forms a complex with SufB and SufD; SufA plays the role of a scaffold protein for assembly of iron-sulfur clusters and delivery to target proteins; SufS is a cysteine desulfurase which mobilizes the sulfur atom from cysteine and provides it to the cluster; SufE has no associated function yet.
Pssm-ID: 213184 [Multi-domain] Cd Length: 200 Bit Score: 44.83 E-value: 9.40e-06
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446512897 2 IKIENLTKSyrtpTGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGID--RPDSGKII 63
Cdd:cd03217 1 LEIKDLHVS----VGGKEILKGVNLTIKKGEVHALMGPNGSGKSTLAKTIMGHPkyEVTEGEIL 60
|
|
| PRK10522 |
PRK10522 |
multidrug transporter membrane component/ATP-binding component; Provisional |
2-63 |
1.06e-05 |
|
multidrug transporter membrane component/ATP-binding component; Provisional
Pssm-ID: 236707 [Multi-domain] Cd Length: 547 Bit Score: 45.73 E-value: 1.06e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446512897 2 IKIENLTKSYRTPTgrhYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKII 63
Cdd:PRK10522 323 LELRNVTFAYQDNG---FSVGPINLTIKRGELLFLIGGNGSGKSTLAMLLTGLYQPQSGEIL 381
|
|
| PRK13409 |
PRK13409 |
ribosome biogenesis/translation initiation ATPase RLI; |
1-153 |
1.11e-05 |
|
ribosome biogenesis/translation initiation ATPase RLI;
Pssm-ID: 184037 [Multi-domain] Cd Length: 590 Bit Score: 45.57 E-value: 1.11e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 1 MIKIENLTKSYRTptgrhyvFKdLNIE---IPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKIITNKTISW-PVGLAG 76
Cdd:PRK13409 340 LVEYPDLTKKLGD-------FS-LEVEggeIYEGEVIGIVGPNGIGKTTFAKLLAGVLKPDEGEVDPELKISYkPQYIKP 411
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 77 GFQGS---LTGRENVKFVARLYakqeelkeKIEFVEEFAeLGKYFDMPIKTYSSGMRSRLGFGLSMAFKFDYYIVDEVTA 153
Cdd:PRK13409 412 DYDGTvedLLRSITDDLGSSYY--------KSEIIKPLQ-LERLLDKNVKDLSGGELQRVAIAACLSRDADLYLLDEPSA 482
|
|
| PRK14243 |
PRK14243 |
phosphate transporter ATP-binding protein; Provisional |
2-49 |
1.14e-05 |
|
phosphate transporter ATP-binding protein; Provisional
Pssm-ID: 184588 [Multi-domain] Cd Length: 264 Bit Score: 45.16 E-value: 1.14e-05
10 20 30 40
....*....|....*....|....*....|....*....|....*...
gi 446512897 2 IKIENLTKSYrtptGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLR 49
Cdd:PRK14243 11 LRTENLNVYY----GSFLAVKNVWLDIPKNQITAFIGPSGCGKSTILR 54
|
|
| ABCG_EPDR |
cd03213 |
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette ... |
5-94 |
1.27e-05 |
|
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily; ABCG transporters are involved in eye pigment (EP) precursor transport, regulation of lipid-trafficking mechanisms, and pleiotropic drug resistance (DR). DR is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. Compared to other members of the ABC transporter subfamilies, the ABCG transporter family is composed of proteins that have an ATP-binding cassette domain at the N-terminus and a TM (transmembrane) domain at the C-terminus.
Pssm-ID: 213180 [Multi-domain] Cd Length: 194 Bit Score: 44.46 E-value: 1.27e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 5 ENLTKSYRTPTGRHY--VFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGG--IDRPDSGKIITNKTISWPVGLAG--GF 78
Cdd:cd03213 7 RNLTVTVKSSPSKSGkqLLKNVSGKAKPGELTAIMGPSGAGKSTLLNALAGrrTGLGVSGEVLINGRPLDKRSFRKiiGY 86
|
90 100
....*....|....*....|...
gi 446512897 79 --Q-----GSLTGRENVKFVARL 94
Cdd:cd03213 87 vpQddilhPTLTVRETLMFAAKL 109
|
|
| MRP_assoc_pro |
TIGR00957 |
multi drug resistance-associated protein (MRP); This model describes multi drug ... |
2-197 |
1.69e-05 |
|
multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]
Pssm-ID: 188098 [Multi-domain] Cd Length: 1522 Bit Score: 45.32 E-value: 1.69e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 2 IKIENLTKSYRTptGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKIITNKTISWPVGLAG-GFQG 80
Cdd:TIGR00957 1285 VEFRNYCLRYRE--DLDLVLRHINVTIHGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDGLNIAKIGLHDlRFKI 1362
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 81 SLTGRENVKFVARL---------YAKQE-----ELKEKIEFVE--------EFAELGkyfdmpiKTYSSGMRSRLGFGLS 138
Cdd:TIGR00957 1363 TIIPQDPVLFSGSLrmnldpfsqYSDEEvwwalELAHLKTFVSalpdkldhECAEGG-------ENLSVGQRQLVCLARA 1435
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 446512897 139 MAFKFDYYIVDEVTAVGDARFKEKCAQLFKERHKESSFLMVSHSLNSLKEFCDVAIVFK 197
Cdd:TIGR00957 1436 LLRKTKILVLDEATAAVDLETDNLIQSTIRTQFEDCTVLTIAHRLNTIMDYTRVIVLDK 1494
|
|
| PRK11147 |
PRK11147 |
ABC transporter ATPase component; Reviewed |
4-62 |
2.06e-05 |
|
ABC transporter ATPase component; Reviewed
Pssm-ID: 236861 [Multi-domain] Cd Length: 635 Bit Score: 44.94 E-value: 2.06e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 4 IENLtkSYRTPtGRHYVfKDLNIEIPSGKSVAFIGRNGAGKSTLLR-MIGGIdRPDSGKI 62
Cdd:PRK11147 322 MENV--NYQID-GKQLV-KDFSAQVQRGDKIALIGPNGCGKTTLLKlMLGQL-QADSGRI 376
|
|
| PRK11147 |
PRK11147 |
ABC transporter ATPase component; Reviewed |
23-63 |
2.32e-05 |
|
ABC transporter ATPase component; Reviewed
Pssm-ID: 236861 [Multi-domain] Cd Length: 635 Bit Score: 44.56 E-value: 2.32e-05
10 20 30 40
....*....|....*....|....*....|....*....|.
gi 446512897 23 DLNIEipSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKII 63
Cdd:PRK11147 23 ELHIE--DNERVCLVGRNGAGKSTLMKILNGEVLLDDGRII 61
|
|
| PLN03073 |
PLN03073 |
ABC transporter F family; Provisional |
20-181 |
2.96e-05 |
|
ABC transporter F family; Provisional
Pssm-ID: 215558 [Multi-domain] Cd Length: 718 Bit Score: 44.47 E-value: 2.96e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 20 VFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKIITNKTISWPVGLAGGFQGSLTGRENVKFVARLYAKQE 99
Cdd:PLN03073 524 LFKNLNFGIDLDSRIAMVGPNGIGKSTILKLISGELQPSSGTVFRSAKVRMAVFSQHHVDGLDLSSNPLLYMMRCFPGVP 603
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 100 ELKEKIEfVEEFAELGKYFDMPIKTYSSGMRSRLGFGlSMAFKFDYYI-VDEVTAVGDARFKEKCAQ---LFkerhkESS 175
Cdd:PLN03073 604 EQKLRAH-LGSFGVTGNLALQPMYTLSGGQKSRVAFA-KITFKKPHILlLDEPSNHLDLDAVEALIQglvLF-----QGG 676
|
....*.
gi 446512897 176 FLMVSH 181
Cdd:PLN03073 677 VLMVSH 682
|
|
| livF |
PRK11614 |
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF; |
1-150 |
4.85e-05 |
|
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;
Pssm-ID: 183231 [Multi-domain] Cd Length: 237 Bit Score: 42.94 E-value: 4.85e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 1 MIKIENLTKSYrtptGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKII-TNKTIS-WPVG----- 73
Cdd:PRK11614 5 MLSFDKVSAHY----GKIQALHEVSLHINQGEIVTLIGANGAGKTTLLGTLCGDPRATSGRIVfDGKDITdWQTAkimre 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 74 -LAGGFQG-----SLTGRENVKfVARLYAKQEELKEKIEFVEE-FAELGKYFDMPIKTYSSGMRSRLGFGLSMAFKFDYY 146
Cdd:PRK11614 81 aVAIVPEGrrvfsRMTVEENLA-MGGFFAERDQFQERIKWVYElFPRLHERRIQRAGTMSGGEQQMLAIGRALMSQPRLL 159
|
....
gi 446512897 147 IVDE 150
Cdd:PRK11614 160 LLDE 163
|
|
| 3a01205 |
TIGR00956 |
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other] |
31-158 |
5.10e-05 |
|
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273362 [Multi-domain] Cd Length: 1394 Bit Score: 43.94 E-value: 5.10e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 31 GKSVAFIGRNGAGKSTLLRMIGGidRPDSGKIITNKTISWPVGLAGGFQ-------------GSLTGRENVKFVARLYAK 97
Cdd:TIGR00956 789 GTLTALMGASGAGKTTLLNVLAE--RVTTGVITGGDRLVNGRPLDSSFQrsigyvqqqdlhlPTSTVRESLRFSAYLRQP 866
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 98 QE-ELKEKIEFVEE---FAELGKYFDMPIKTYSSGM----RSRLGFGLSMAFKFDYYI-VDEVTAVGDAR 158
Cdd:TIGR00956 867 KSvSKSEKMEYVEEvikLLEMESYADAVVGVPGEGLnveqRKRLTIGVELVAKPKLLLfLDEPTSGLDSQ 936
|
|
| AAA |
smart00382 |
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ... |
30-159 |
5.17e-05 |
|
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.
Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 41.98 E-value: 5.17e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 30 SGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKIITNKTiswpvglaggfqgsltgrenvkfvarlyakqeelkEKIEFVE 109
Cdd:smart00382 1 PGEVILIVGPPGSGKTTLARALARELGPPGGGVIYIDG-----------------------------------EDILEEV 45
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|
gi 446512897 110 EFAELGKYFDMPIKTYSSGMRSRLGFGLSMAFKFDYYIVDEVTAVGDARF 159
Cdd:smart00382 46 LDQLLLIIVGGKKASGSGELRLRLALALARKLKPDVLILDEITSLLDAEQ 95
|
|
| tauB |
PRK11248 |
taurine ABC transporter ATP-binding subunit; |
1-166 |
5.45e-05 |
|
taurine ABC transporter ATP-binding subunit;
Pssm-ID: 183056 [Multi-domain] Cd Length: 255 Bit Score: 43.15 E-value: 5.45e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 1 MIKIENLTKSYrtptGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKI-ITNKTISWPvGLAGG-- 77
Cdd:PRK11248 1 MLQISHLYADY----GGKPALEDINLTLESGELLVVLGPSGCGKTTLLNLIAGFVPYQHGSItLDGKPVEGP-GAERGvv 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 78 FQ--GSLTGR---ENVKFVARL----YAKQEELKEKIEFVEEFAELGKYFdmpIKTYSSGMRSRLGFGLSMAFKFDYYIV 148
Cdd:PRK11248 76 FQneGLLPWRnvqDNVAFGLQLagveKMQRLEIAHQMLKKVGLEGAEKRY---IWQLSGGQRQRVGIARALAANPQLLLL 152
|
170
....*....|....*...
gi 446512897 149 DEVTAVGDARFKEKCAQL 166
Cdd:PRK11248 153 DEPFGALDAFTREQMQTL 170
|
|
| ABCC_CFTR1 |
cd03291 |
ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The ... |
20-90 |
5.54e-05 |
|
ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The CFTR subfamily domain 1. The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits, or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.
Pssm-ID: 213258 [Multi-domain] Cd Length: 282 Bit Score: 42.92 E-value: 5.54e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446512897 20 VFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKIITNKTISWPVGLAGGFQGSLtgRENVKF 90
Cdd:cd03291 52 VLKNINLKIEKGEMLAITGSTGSGKTSLLMLILGELEPSEGKIKHSGRISFSSQFSWIMPGTI--KENIIF 120
|
|
| PRK10636 |
PRK10636 |
putative ABC transporter ATP-binding protein; Provisional |
1-68 |
9.62e-05 |
|
putative ABC transporter ATP-binding protein; Provisional
Pssm-ID: 236729 [Multi-domain] Cd Length: 638 Bit Score: 42.85 E-value: 9.62e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446512897 1 MIKIENLTKSYrtptGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKIITNKTI 68
Cdd:PRK10636 312 LLKMEKVSAGY----GDRIILDSIKLNLVPGSRIGLLGRNGAGKSTLIKLLAGELAPVSGEIGLAKGI 375
|
|
| ABCG_PDR_domain2 |
cd03232 |
Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding ... |
5-158 |
9.64e-05 |
|
Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213199 [Multi-domain] Cd Length: 192 Bit Score: 41.85 E-value: 9.64e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 5 ENLTKSYRTPTGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGidRPDSGKIITNKTISwpvglaggfqgsltG 84
Cdd:cd03232 7 KNLNYTVPVKGGKRQLLNNISGYVKPGTLTALMGESGAGKTTLLDVLAG--RKTAGVITGEILIN--------------G 70
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446512897 85 RENVKFVARL--YAKQEELKEKIEFVEEFAElgkyFDMPIKTYSSGMRSRLGFGLSMAFKFDYYIVDEVTAVGDAR 158
Cdd:cd03232 71 RPLDKNFQRStgYVEQQDVHSPNLTVREALR----FSALLRGLSVEQRKRLTIGVELAAKPSILFLDEPTSGLDSQ 142
|
|
| PRK15134 |
PRK15134 |
microcin C ABC transporter ATP-binding protein YejF; Provisional |
1-197 |
1.59e-04 |
|
microcin C ABC transporter ATP-binding protein YejF; Provisional
Pssm-ID: 237917 [Multi-domain] Cd Length: 529 Bit Score: 42.00 E-value: 1.59e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 1 MIKIENLTKSY-------RTPTGRHYVFKDLNIEIPSGKSVAFIGRNGAGKST----LLRMI---GGIDRPDSGKIITNK 66
Cdd:PRK15134 275 LLDVEQLQVAFpirkgilKRTVDHNVVVKNISFTLRPGETLGLVGESGSGKSTtglaLLRLInsqGEIWFDGQPLHNLNR 354
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 67 TISWPV--GLAGGFQ---GSLTGRENV-KFVA--------RLYAKQEELkekiEFVEEFAELG-------KYfdmPIKtY 125
Cdd:PRK15134 355 RQLLPVrhRIQVVFQdpnSSLNPRLNVlQIIEeglrvhqpTLSAAQREQ----QVIAVMEEVGldpetrhRY---PAE-F 426
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446512897 126 SSGMRSRLGFGLSMAFKFDYYIVDEVTAVGDARFKEKCAQLFK---ERHKeSSFLMVSHSLNSLKEFCDVAIVFK 197
Cdd:PRK15134 427 SGGQRQRIAIARALILKPSLIILDEPTSSLDKTVQAQILALLKslqQKHQ-LAYLFISHDLHVVRALCHQVIVLR 500
|
|
| CFTR_protein |
TIGR01271 |
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ... |
4-48 |
1.77e-04 |
|
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]
Pssm-ID: 273530 [Multi-domain] Cd Length: 1490 Bit Score: 42.20 E-value: 1.77e-04
10 20 30 40
....*....|....*....|....*....|....*....|....*
gi 446512897 4 IENLTKSYrTPTGRHyVFKDLNIEIPSGKSVAFIGRNGAGKSTLL 48
Cdd:TIGR01271 1220 VQGLTAKY-TEAGRA-VLQDLSFSVEGGQRVGLLGRTGSGKSTLL 1262
|
|
| PRK10982 |
PRK10982 |
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional |
23-63 |
2.04e-04 |
|
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
Pssm-ID: 182880 [Multi-domain] Cd Length: 491 Bit Score: 41.64 E-value: 2.04e-04
10 20 30 40
....*....|....*....|....*....|....*....|.
gi 446512897 23 DLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKII 63
Cdd:PRK10982 16 NVNLKVRPHSIHALMGENGAGKSTLLKCLFGIYQKDSGSIL 56
|
|
| PRK10762 |
PRK10762 |
D-ribose transporter ATP binding protein; Provisional |
31-63 |
2.18e-04 |
|
D-ribose transporter ATP binding protein; Provisional
Pssm-ID: 236755 [Multi-domain] Cd Length: 501 Bit Score: 41.53 E-value: 2.18e-04
10 20 30
....*....|....*....|....*....|...
gi 446512897 31 GKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKII 63
Cdd:PRK10762 30 GRVMALVGENGAGKSTMMKVLTGIYTRDAGSIL 62
|
|
| PRK03695 |
PRK03695 |
vitamin B12-transporter ATPase; Provisional |
24-67 |
4.67e-04 |
|
vitamin B12-transporter ATPase; Provisional
Pssm-ID: 235150 [Multi-domain] Cd Length: 248 Bit Score: 40.30 E-value: 4.67e-04
10 20 30 40
....*....|....*....|....*....|....*....|....
gi 446512897 24 LNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIdRPDSGKIITNKT 67
Cdd:PRK03695 15 LSAEVRAGEILHLVGPNGAGKSTLLARMAGL-LPGSGSIQFAGQ 57
|
|
| COG3950 |
COG3950 |
Predicted ATP-binding protein involved in virulence [General function prediction only]; |
2-51 |
4.96e-04 |
|
Predicted ATP-binding protein involved in virulence [General function prediction only];
Pssm-ID: 443150 [Multi-domain] Cd Length: 276 Bit Score: 39.98 E-value: 4.96e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 446512897 2 IKIENLtksyrtptgRHyvFKDLNIEIPSGKSV-AFIGRNGAGKSTLLRMI 51
Cdd:COG3950 6 LTIENF---------RG--FEDLEIDFDNPPRLtVLVGENGSGKTTLLEAI 45
|
|
| YbjD |
COG3593 |
Predicted ATP-dependent endonuclease of the OLD family, contains P-loop ATPase and TOPRIM ... |
2-49 |
5.07e-04 |
|
Predicted ATP-dependent endonuclease of the OLD family, contains P-loop ATPase and TOPRIM domains [Replication, recombination and repair];
Pssm-ID: 442812 [Multi-domain] Cd Length: 359 Bit Score: 40.37 E-value: 5.07e-04
10 20 30 40
....*....|....*....|....*....|....*....|....*...
gi 446512897 2 IKIENltksYRTptgrhyvFKDLNIEIPSGKSVaFIGRNGAGKSTLLR 49
Cdd:COG3593 6 IKIKN----FRS-------IKDLSIELSDDLTV-LVGENNSGKSSILE 41
|
|
| MglA |
COG1129 |
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; |
3-62 |
5.18e-04 |
|
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440745 [Multi-domain] Cd Length: 497 Bit Score: 40.39 E-value: 5.18e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 3 KIENLTksyrtptgRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKI 62
Cdd:COG1129 258 EVEGLS--------VGGVVRDVSFSVRAGEILGIAGLVGAGRTELARALFGADPADSGEI 309
|
|
| PRK10584 |
PRK10584 |
putative ABC transporter ATP-binding protein YbbA; Provisional |
28-191 |
5.89e-04 |
|
putative ABC transporter ATP-binding protein YbbA; Provisional
Pssm-ID: 182569 [Multi-domain] Cd Length: 228 Bit Score: 39.76 E-value: 5.89e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 28 IPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKI-ITNKTIS------------WPVGLAggFQG-----SLTGRENVK 89
Cdd:PRK10584 33 VKRGETIALIGESGSGKSTLLAILAGLDDGSSGEVsLVGQPLHqmdeearaklraKHVGFV--FQSfmlipTLNALENVE 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 90 FVARLYAKQE--ELKEKIEFVEEFAeLGKYFD-MPIKtYSSGMRSRLGFGLSMAFKFDYYIVDEVTAVGDARFKEKCAQL 166
Cdd:PRK10584 111 LPALLRGESSrqSRNGAKALLEQLG-LGKRLDhLPAQ-LSGGEQQRVALARAFNGRPDVLFADEPTGNLDRQTGDKIADL 188
|
170 180
....*....|....*....|....*..
gi 446512897 167 FKERHKE--SSFLMVSHSlNSLKEFCD 191
Cdd:PRK10584 189 LFSLNREhgTTLILVTHD-LQLAARCD 214
|
|
| PRK13657 |
PRK13657 |
glucan ABC transporter ATP-binding protein/ permease; |
2-211 |
5.89e-04 |
|
glucan ABC transporter ATP-binding protein/ permease;
Pssm-ID: 184214 [Multi-domain] Cd Length: 588 Bit Score: 40.33 E-value: 5.89e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 2 IKIENLTKSYrtPTGRHYVFkDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKI---------ITNKTISWPV 72
Cdd:PRK13657 335 VEFDDVSFSY--DNSRQGVE-DVSFEAKPGQTVAIVGPTGAGKSTLINLLQRVFDPQSGRIlidgtdirtVTRASLRRNI 411
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 73 GL----AGGFQGSLtgRENVKfVARLYAKQEELKEKIE------FVEEfAELGkyFDMPI----KTYSSGMRSRLGFGLS 138
Cdd:PRK13657 412 AVvfqdAGLFNRSI--EDNIR-VGRPDATDEEMRAAAEraqahdFIER-KPDG--YDTVVgergRQLSGGERQRLAIARA 485
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446512897 139 MAFKFDYYIVDEVTAVGDARFKEKCAQLFKE-RHKESSFLmVSHSLNSLKEfCDVAIVFKNSYII---GYYENVQSG 211
Cdd:PRK13657 486 LLKDPPILILDEATSALDVETEAKVKAALDElMKGRTTFI-IAHRLSTVRN-ADRILVFDNGRVVesgSFDELVARG 560
|
|
| 3a01204 |
TIGR00955 |
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, ... |
30-137 |
6.79e-04 |
|
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273361 [Multi-domain] Cd Length: 617 Bit Score: 40.03 E-value: 6.79e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 30 SGKSVAFIGRNGAGKSTLLRMIGGIDRPD---SGKIITN---------KTISWPVGLAGGFQGSLTGRENVKFVARLYAK 97
Cdd:TIGR00955 50 PGELLAVMGSSGAGKTTLMNALAFRSPKGvkgSGSVLLNgmpidakemRAISAYVQQDDLFIPTLTVREHLMFQAHLRMP 129
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|
gi 446512897 98 QEELK-EKIEFVEEFAE---LGKYFDMPI------KTYSSGMRSRLGFGL 137
Cdd:TIGR00955 130 RRVTKkEKRERVDEVLQalgLRKCANTRIgvpgrvKGLSGGERKRLAFAS 179
|
|
| ycf16 |
CHL00131 |
sulfate ABC transporter protein; Validated |
1-53 |
8.24e-04 |
|
sulfate ABC transporter protein; Validated
Pssm-ID: 214372 [Multi-domain] Cd Length: 252 Bit Score: 39.24 E-value: 8.24e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 446512897 1 MIKIENLTKSyrtpTGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGG 53
Cdd:CHL00131 7 ILEIKNLHAS----VNENEILKGLNLSINKGEIHAIMGPNGSGKSTLSKVIAG 55
|
|
| PLN03232 |
PLN03232 |
ABC transporter C family member; Provisional |
2-90 |
1.17e-03 |
|
ABC transporter C family member; Provisional
Pssm-ID: 215640 [Multi-domain] Cd Length: 1495 Bit Score: 39.57 E-value: 1.17e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 2 IKIENLTKSYRTPTGRHyVFKDLNIEIPSGKSVAFIGRNGAGKSTLLR-MIGGIDRPDSGKIITNKTISWPVGLAGGFQG 80
Cdd:PLN03232 615 ISIKNGYFSWDSKTSKP-TLSDINLEIPVGSLVAIVGGTGEGKTSLISaMLGELSHAETSSVVIRGSVAYVPQVSWIFNA 693
|
90
....*....|
gi 446512897 81 SLtgRENVKF 90
Cdd:PLN03232 694 TV--RENILF 701
|
|
| livG |
PRK11300 |
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional |
25-63 |
1.53e-03 |
|
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional
Pssm-ID: 183080 [Multi-domain] Cd Length: 255 Bit Score: 38.43 E-value: 1.53e-03
10 20 30
....*....|....*....|....*....|....*....
gi 446512897 25 NIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKII 63
Cdd:PRK11300 25 NLEVREQEIVSLIGPNGAGKTTVFNCLTGFYKPTGGTIL 63
|
|
| DLIC |
pfam05783 |
Dynein light intermediate chain (DLIC); This family consists of several eukaryotic dynein ... |
27-61 |
1.53e-03 |
|
Dynein light intermediate chain (DLIC); This family consists of several eukaryotic dynein light intermediate chain proteins. The light intermediate chains (LICs) of cytoplasmic dynein consist of multiple isoforms, which undergo post-translational modification to produce a large number of species. DLIC1 is known to be involved in assembly, organization, and function of centrosomes and mitotic spindles when bound to pericentrin. DLIC2 is a subunit of cytoplasmic dynein 2 that may play a role in maintaining Golgi organization by binding cytoplasmic dynein 2 to its Golgi-associated cargo.
Pssm-ID: 368612 Cd Length: 468 Bit Score: 39.06 E-value: 1.53e-03
10 20 30
....*....|....*....|....*....|....*
gi 446512897 27 EIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGK 61
Cdd:pfam05783 21 KLPSGKNVLVLGEDGSGKTTLIAKLQGVEHPKKGR 55
|
|
| Rli1 |
COG1245 |
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ... |
21-183 |
1.54e-03 |
|
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];
Pssm-ID: 440858 [Multi-domain] Cd Length: 592 Bit Score: 39.00 E-value: 1.54e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 21 FKDLNIEIP-SGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKIitNKTISWPVGLAgGFQGSltgrENVKFVARLYAKQ- 98
Cdd:COG1245 88 FRLYGLPVPkKGKVTGILGPNGIGKSTALKILSGELKPNLGDY--DEEPSWDEVLK-RFRGT----ELQDYFKKLANGEi 160
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 99 --------------------EELKEKI-------EFVEEFaELGKYFDMPIKTYSSGMRSRLGFGLSMAFKFDYYIVDEV 151
Cdd:COG1245 161 kvahkpqyvdlipkvfkgtvRELLEKVdergkldELAEKL-GLENILDRDISELSGGELQRVAIAAALLRDADFYFFDEP 239
|
170 180 190
....*....|....*....|....*....|...
gi 446512897 152 TAVGDARFKEKCAQLFKERHKE-SSFLMVSHSL 183
Cdd:COG1245 240 SSYLDIYQRLNVARLIRELAEEgKYVLVVEHDL 272
|
|
| ABCC_CFTR2 |
cd03289 |
ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator ... |
2-48 |
2.00e-03 |
|
ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.
Pssm-ID: 213256 [Multi-domain] Cd Length: 275 Bit Score: 38.30 E-value: 2.00e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*..
gi 446512897 2 IKIENLTKSYRTptGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTLL 48
Cdd:cd03289 3 MTVKDLTAKYTE--GGNAVLENISFSISPGQRVGLLGRTGSGKSTLL 47
|
|
| YejF |
COG4172 |
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ... |
1-62 |
2.77e-03 |
|
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 443332 [Multi-domain] Cd Length: 533 Bit Score: 38.13 E-value: 2.77e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446512897 1 MIKIENLTKSYRTPTGRHYVFKDLNIEIPSGKSVAFIGRNGAGKS----TLLRMIGGIDRPDSGKI 62
Cdd:COG4172 6 LLSVEDLSVAFGQGGGTVEAVKGVSFDIAAGETLALVGESGSGKSvtalSILRLLPDPAAHPSGSI 71
|
|
| COG4637 |
COG4637 |
Predicted ATPase [General function prediction only]; |
2-151 |
4.17e-03 |
|
Predicted ATPase [General function prediction only];
Pssm-ID: 443675 [Multi-domain] Cd Length: 371 Bit Score: 37.60 E-value: 4.17e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446512897 2 IKIENLtKSYRtptgrhyvfkdlNIEIPSGKSVAFIGRNGAGKSTL---LRMIGGIdrpdsgkiitnktiswpvgLAGGF 78
Cdd:COG4637 5 IRIKNF-KSLR------------DLELPLGPLTVLIGANGSGKSNLldaLRFLSDA-------------------ARGGL 52
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446512897 79 QGSLTGRENVKFVarLYAKQEELKEKIEFVEEFAELgkyfDMPIKTYssgmrsRLGFGLSmAFKFDYYIVDEV 151
Cdd:COG4637 53 QDALARRGGLEEL--LWRGPRTITEPIRLELEFAEE----DERDLRY------ELELGLP-EPGGRPEVKEER 112
|
|
| BtuD |
COG4138 |
ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism]; ... |
24-62 |
4.95e-03 |
|
ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism];
Pssm-ID: 443313 [Multi-domain] Cd Length: 248 Bit Score: 37.13 E-value: 4.95e-03
10 20 30
....*....|....*....|....*....|....*....
gi 446512897 24 LNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIdRPDSGKI 62
Cdd:COG4138 15 ISAQVNAGELIHLIGPNGAGKSTLLARMAGL-LPGQGEI 52
|
|
| PTZ00243 |
PTZ00243 |
ABC transporter; Provisional |
22-70 |
8.90e-03 |
|
ABC transporter; Provisional
Pssm-ID: 240327 [Multi-domain] Cd Length: 1560 Bit Score: 37.07 E-value: 8.90e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 446512897 22 KDLNIEIPSGKSVAFIGRNGAGKSTLLRMIGGIDRPDSGKIITNKTISW 70
Cdd:PTZ00243 677 RDVSVSVPRGKLTVVLGATGSGKSTLLQSLLSQFEISEGRVWAERSIAY 725
|
|
| YejF |
COG4172 |
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ... |
2-63 |
9.92e-03 |
|
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 443332 [Multi-domain] Cd Length: 533 Bit Score: 36.59 E-value: 9.92e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446512897 2 IKIENLTKSY-------RTPTGRHYVFKDLNIEIPSGKSVAFIGRNGAGKSTL----LRMIggidrPDSGKII 63
Cdd:COG4172 276 LEARDLKVWFpikrglfRRTVGHVKAVDGVSLTLRRGETLGLVGESGSGKSTLglalLRLI-----PSEGEIR 343
|
|
| |
