|
Name |
Accession |
Description |
Interval |
E-value |
| MngR |
COG2188 |
DNA-binding transcriptional regulator, GntR family [Transcription]; |
8-239 |
6.66e-76 |
|
DNA-binding transcriptional regulator, GntR family [Transcription];
Pssm-ID: 441791 [Multi-domain] Cd Length: 238 Bit Score: 229.36 E-value: 6.66e-76
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494717 8 KSAKPLYKQLEDALKEAIARGEYKPGQQIPTENELSVRWQVSRVTVRKALDALTRENLLTRVSGKGTFVSSEKFQRSMIG 87
Cdd:COG2188 1 SSPVPLYLQIADALRERIESGELPPGDRLPSERELAEEFGVSRMTVRKALDELVEEGLLERRQGRGTFVAEPKIEYPLSR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494717 88 IMSFSELCQSQGRRPGSRTIKSVFESVDNETKALLNMNDGEKAVVIERIRYADDVAVSLETVHLPP-RFAFLLDEDLNNH 166
Cdd:COG2188 81 LTSFTEELRARGREPSTRVLSAERVPADEEVAEALGLPPGAPVLRIERLRLADGEPVALETSYLPAaLFPGLLEEDLETG 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446494717 167 SLYECLREKHHLWFTHSRKMIELVYASFEVAHYLGVNEGYPLILIKSEMIDNKGELSCVSQQLIVGDKIRFTV 239
Cdd:COG2188 161 SLYELLEERYGLRITRAEQRIEAVLADAEEAELLGVPPGAPVLVIERVTYDADGRPVEYSRSYYRGDRYRFVV 233
|
|
| PRK11402 |
PRK11402 |
transcriptional regulator PhoB; |
6-239 |
3.21e-44 |
|
transcriptional regulator PhoB;
Pssm-ID: 183118 [Multi-domain] Cd Length: 241 Bit Score: 148.83 E-value: 3.21e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494717 6 DSKSAKPLYKQLEDALKEAIARGEYKPGQQIPTENELSVRWQVSRVTVRKALDALTRENLLTRVSGKGTFVSSEKFQRSM 85
Cdd:PRK11402 3 DRYSHQLLYATVRQRLLDDIAQGVYQAGQQIPTENELCTQYNVSRITIRKAISDLVADGVLIRWQGKGTFVQSQKVENAL 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494717 86 IGIMSFSELCQSQGRRPGSRTIKSVFESVDNETKaLLNMNDGEKAVVIERIRYADDVAVSLETVHLP-PRFAFLLDEDLN 164
Cdd:PRK11402 83 LTVSGFTDFGVSQGKATKEKVIEQERVSAAPFCE-KLNIPGNSEVFHLCRVMYLDKEPLFIDSSWIPlSRYPDFDEIYVE 161
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446494717 165 NHSLYECLREKHHLWFTHSRKMIELVYASFEVAHYLGVNEGYPLILIKSEMIDNKGELSCVSQQLIVGDKIRFTV 239
Cdd:PRK11402 162 GSSTYQLFQERFDTRVVSDKKTIDIFAATRPEAKWLKCELGEPLFRISKIAFDQNDKPVHVSELFCRANRVTLTI 236
|
|
| UTRA |
pfam07702 |
UTRA domain; The UbiC transcription regulator-associated (UTRA) domain is a conserved ... |
97-236 |
7.92e-36 |
|
UTRA domain; The UbiC transcription regulator-associated (UTRA) domain is a conserved ligand-binding domain that has a similar fold to pfam04345. It is believed to modulate activity of bacterial transcription factors in response to binding small molecules sugar phosphates and urocanate, Matilla et. al., FEMS Microbiology Reviews, fuab043, 45, 2021, 1. https://doi.org/10.1093/femsre/fuab043).
Pssm-ID: 429607 [Multi-domain] Cd Length: 141 Bit Score: 123.86 E-value: 7.92e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494717 97 SQGRRPGSRTIKSVFESVDNETKALLNMNDGEKAVVIERIRYADDVAVSLETVHLPP-RFAFLLDEDLNNHSLYECLREK 175
Cdd:pfam07702 1 AQGREPKTEVLSLEEVPASAEIAEALGLPPGEPVYRIERLRYADGEPVALEEDYLPAeLVPDLLEEDLEEGSLYDYLEER 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446494717 176 HHLWFTHSRKMIELVYASFEVAHYLGVNEGYPLILIKSEMIDNKGELSCVSQQLIVGDKIR 236
Cdd:pfam07702 81 YGLPITRAEQTIEAVLADAEEAELLGISPGAPVLLIERVTYDQDGRPVEYSRSYYRGDRYR 141
|
|
| C_P_lyase_phnF |
TIGR02325 |
phosphonates metabolism transcriptional regulator PhnF; All members of the seed alignment for ... |
8-239 |
2.33e-31 |
|
phosphonates metabolism transcriptional regulator PhnF; All members of the seed alignment for this family are predicted helix-turn-helix transcriptional regulatory proteins of the broader gntR and are found associated with genes for the import and degradation of phosphonates and/or related compounds (e.g. phosphonites) with a direct C-P bond. [Transport and binding proteins, Anions, Regulatory functions, DNA interactions]
Pssm-ID: 131378 [Multi-domain] Cd Length: 238 Bit Score: 115.27 E-value: 2.33e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494717 8 KSAKPLYKQLEDALKEAIARGEYKPGQQIPTENELSVRWQVSRVTVRKALDALTRENLLTRVSGKGTFVSSEKFQRSMIG 87
Cdd:TIGR02325 4 TSGVALWRQIADKIEQEIAAGHLRAGDYLPAEMQLAERFGVNRHTVRRAIAALVERGLLRAEQGRGTFVAARRIDYPLSA 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494717 88 IMSFSELCQSQGRRPGSRTIKSVFESVDNETKALLNMNDGEKAVVIERIRYADDVAVSLETVHLPP-RFAFLLDEDLNNH 166
Cdd:TIGR02325 84 RTRFSQNLADQGREPTGELLLSDLEPASAELADALGLTVGAPLVRLETLRKADGRPLCRATTWFPAaRFPGIGQAYAASG 163
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446494717 167 SLYECLREKHHLWFTHSRKMIELVYASFEVAHYLGVNEGYPLILIKSEMIDNKGELSCVSQQLIVGDKIRFTV 239
Cdd:TIGR02325 164 SITDALREQGVADYRRSSTRISARHADAKDCARLELPPGRPLLVVQALNHDGEGRPVQYSVSRFRADRVEFTM 236
|
|
| UTRA |
smart00866 |
The UbiC transcription regulator-associated (UTRA) domain is a conserved ligand-binding domain; ... |
97-236 |
7.71e-27 |
|
The UbiC transcription regulator-associated (UTRA) domain is a conserved ligand-binding domain; It has a similar fold to HutC/FarR-like bacterial transcription factors of the GntR family. It is believed to modulate activity of bacterial transcription factors in response to binding small molecules.
Pssm-ID: 214869 [Multi-domain] Cd Length: 143 Bit Score: 100.83 E-value: 7.71e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494717 97 SQGRRPGSRTIKSVFESVDNETKALLNMNDGEKAVVIERIRYADDVAVSLETVHLPP-RFAFLLDEDLnNHSLYECLREK 175
Cdd:smart00866 1 AQGRKPTTKVLSFERVPADEELAEALGLPPGDPVYRIERLRLADGEPVALETTYLPAaLFPGLLEEDL-SGSLYEYLEER 79
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446494717 176 HHL---WFTHSRKMIELVYASFEVAHYLGVNEGYPLILIKSEMIDNKGELSCVSQQLIVGDKIR 236
Cdd:smart00866 80 LGLkivRSTRAEQTITAVLADEEEAELLGLPPGAPLLVVERVTYDDDGRPVEYSRSYYRGDRFR 143
|
|
| WHTH_GntR |
cd07377 |
Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional ... |
12-77 |
3.24e-26 |
|
Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; This CD represents the winged HTH DNA-binding domain of the GntR (named after the gluconate operon repressor in Bacillus subtilis) family of bacterial transcriptional regulators and their putative homologs found in eukaryota and archaea. The GntR family has over 6000 members distributed among almost all bacterial species, which is comprised of FadR, HutC, MocR, YtrA, AraR, PlmA, and other subfamilies for the regulation of the most varied biological process. The monomeric proteins of the GntR family are characterized by two function domains: a small highly conserved winged helix-turn-helix prokaryotic DNA binding domain in the N-terminus, and a very diverse regulatory ligand-binding domain in the C-terminus for effector-binding/oligomerization, which provides the basis for the subfamily classifications. Binding of the effector to GntR-like transcriptional regulators is presumed to result in a conformational change that regulates the DNA-binding affinity of the repressor. The GntR-like proteins bind as dimers, where each monomer recognizes a half-site of 2-fold symmetric DNA sequences.
Pssm-ID: 153418 [Multi-domain] Cd Length: 66 Bit Score: 96.75 E-value: 3.24e-26
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446494717 12 PLYKQLEDALKEAIARGEYKPGQQIPTENELSVRWQVSRVTVRKALDALTRENLLTRVSGKGTFVS 77
Cdd:cd07377 1 PLYEQIADQLREAILSGELKPGDRLPSERELAEELGVSRTTVREALRELEAEGLVERRPGRGTFVA 66
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| MngR |
COG2188 |
DNA-binding transcriptional regulator, GntR family [Transcription]; |
8-239 |
6.66e-76 |
|
DNA-binding transcriptional regulator, GntR family [Transcription];
Pssm-ID: 441791 [Multi-domain] Cd Length: 238 Bit Score: 229.36 E-value: 6.66e-76
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494717 8 KSAKPLYKQLEDALKEAIARGEYKPGQQIPTENELSVRWQVSRVTVRKALDALTRENLLTRVSGKGTFVSSEKFQRSMIG 87
Cdd:COG2188 1 SSPVPLYLQIADALRERIESGELPPGDRLPSERELAEEFGVSRMTVRKALDELVEEGLLERRQGRGTFVAEPKIEYPLSR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494717 88 IMSFSELCQSQGRRPGSRTIKSVFESVDNETKALLNMNDGEKAVVIERIRYADDVAVSLETVHLPP-RFAFLLDEDLNNH 166
Cdd:COG2188 81 LTSFTEELRARGREPSTRVLSAERVPADEEVAEALGLPPGAPVLRIERLRLADGEPVALETSYLPAaLFPGLLEEDLETG 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446494717 167 SLYECLREKHHLWFTHSRKMIELVYASFEVAHYLGVNEGYPLILIKSEMIDNKGELSCVSQQLIVGDKIRFTV 239
Cdd:COG2188 161 SLYELLEERYGLRITRAEQRIEAVLADAEEAELLGVPPGAPVLVIERVTYDADGRPVEYSRSYYRGDRYRFVV 233
|
|
| PRK11402 |
PRK11402 |
transcriptional regulator PhoB; |
6-239 |
3.21e-44 |
|
transcriptional regulator PhoB;
Pssm-ID: 183118 [Multi-domain] Cd Length: 241 Bit Score: 148.83 E-value: 3.21e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494717 6 DSKSAKPLYKQLEDALKEAIARGEYKPGQQIPTENELSVRWQVSRVTVRKALDALTRENLLTRVSGKGTFVSSEKFQRSM 85
Cdd:PRK11402 3 DRYSHQLLYATVRQRLLDDIAQGVYQAGQQIPTENELCTQYNVSRITIRKAISDLVADGVLIRWQGKGTFVQSQKVENAL 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494717 86 IGIMSFSELCQSQGRRPGSRTIKSVFESVDNETKaLLNMNDGEKAVVIERIRYADDVAVSLETVHLP-PRFAFLLDEDLN 164
Cdd:PRK11402 83 LTVSGFTDFGVSQGKATKEKVIEQERVSAAPFCE-KLNIPGNSEVFHLCRVMYLDKEPLFIDSSWIPlSRYPDFDEIYVE 161
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446494717 165 NHSLYECLREKHHLWFTHSRKMIELVYASFEVAHYLGVNEGYPLILIKSEMIDNKGELSCVSQQLIVGDKIRFTV 239
Cdd:PRK11402 162 GSSTYQLFQERFDTRVVSDKKTIDIFAATRPEAKWLKCELGEPLFRISKIAFDQNDKPVHVSELFCRANRVTLTI 236
|
|
| UTRA |
pfam07702 |
UTRA domain; The UbiC transcription regulator-associated (UTRA) domain is a conserved ... |
97-236 |
7.92e-36 |
|
UTRA domain; The UbiC transcription regulator-associated (UTRA) domain is a conserved ligand-binding domain that has a similar fold to pfam04345. It is believed to modulate activity of bacterial transcription factors in response to binding small molecules sugar phosphates and urocanate, Matilla et. al., FEMS Microbiology Reviews, fuab043, 45, 2021, 1. https://doi.org/10.1093/femsre/fuab043).
Pssm-ID: 429607 [Multi-domain] Cd Length: 141 Bit Score: 123.86 E-value: 7.92e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494717 97 SQGRRPGSRTIKSVFESVDNETKALLNMNDGEKAVVIERIRYADDVAVSLETVHLPP-RFAFLLDEDLNNHSLYECLREK 175
Cdd:pfam07702 1 AQGREPKTEVLSLEEVPASAEIAEALGLPPGEPVYRIERLRYADGEPVALEEDYLPAeLVPDLLEEDLEEGSLYDYLEER 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446494717 176 HHLWFTHSRKMIELVYASFEVAHYLGVNEGYPLILIKSEMIDNKGELSCVSQQLIVGDKIR 236
Cdd:pfam07702 81 YGLPITRAEQTIEAVLADAEEAELLGISPGAPVLLIERVTYDQDGRPVEYSRSYYRGDRYR 141
|
|
| C_P_lyase_phnF |
TIGR02325 |
phosphonates metabolism transcriptional regulator PhnF; All members of the seed alignment for ... |
8-239 |
2.33e-31 |
|
phosphonates metabolism transcriptional regulator PhnF; All members of the seed alignment for this family are predicted helix-turn-helix transcriptional regulatory proteins of the broader gntR and are found associated with genes for the import and degradation of phosphonates and/or related compounds (e.g. phosphonites) with a direct C-P bond. [Transport and binding proteins, Anions, Regulatory functions, DNA interactions]
Pssm-ID: 131378 [Multi-domain] Cd Length: 238 Bit Score: 115.27 E-value: 2.33e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494717 8 KSAKPLYKQLEDALKEAIARGEYKPGQQIPTENELSVRWQVSRVTVRKALDALTRENLLTRVSGKGTFVSSEKFQRSMIG 87
Cdd:TIGR02325 4 TSGVALWRQIADKIEQEIAAGHLRAGDYLPAEMQLAERFGVNRHTVRRAIAALVERGLLRAEQGRGTFVAARRIDYPLSA 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494717 88 IMSFSELCQSQGRRPGSRTIKSVFESVDNETKALLNMNDGEKAVVIERIRYADDVAVSLETVHLPP-RFAFLLDEDLNNH 166
Cdd:TIGR02325 84 RTRFSQNLADQGREPTGELLLSDLEPASAELADALGLTVGAPLVRLETLRKADGRPLCRATTWFPAaRFPGIGQAYAASG 163
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446494717 167 SLYECLREKHHLWFTHSRKMIELVYASFEVAHYLGVNEGYPLILIKSEMIDNKGELSCVSQQLIVGDKIRFTV 239
Cdd:TIGR02325 164 SITDALREQGVADYRRSSTRISARHADAKDCARLELPPGRPLLVVQALNHDGEGRPVQYSVSRFRADRVEFTM 236
|
|
| UTRA |
smart00866 |
The UbiC transcription regulator-associated (UTRA) domain is a conserved ligand-binding domain; ... |
97-236 |
7.71e-27 |
|
The UbiC transcription regulator-associated (UTRA) domain is a conserved ligand-binding domain; It has a similar fold to HutC/FarR-like bacterial transcription factors of the GntR family. It is believed to modulate activity of bacterial transcription factors in response to binding small molecules.
Pssm-ID: 214869 [Multi-domain] Cd Length: 143 Bit Score: 100.83 E-value: 7.71e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494717 97 SQGRRPGSRTIKSVFESVDNETKALLNMNDGEKAVVIERIRYADDVAVSLETVHLPP-RFAFLLDEDLnNHSLYECLREK 175
Cdd:smart00866 1 AQGRKPTTKVLSFERVPADEELAEALGLPPGDPVYRIERLRLADGEPVALETTYLPAaLFPGLLEEDL-SGSLYEYLEER 79
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446494717 176 HHL---WFTHSRKMIELVYASFEVAHYLGVNEGYPLILIKSEMIDNKGELSCVSQQLIVGDKIR 236
Cdd:smart00866 80 LGLkivRSTRAEQTITAVLADEEEAELLGLPPGAPLLVVERVTYDDDGRPVEYSRSYYRGDRFR 143
|
|
| WHTH_GntR |
cd07377 |
Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional ... |
12-77 |
3.24e-26 |
|
Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; This CD represents the winged HTH DNA-binding domain of the GntR (named after the gluconate operon repressor in Bacillus subtilis) family of bacterial transcriptional regulators and their putative homologs found in eukaryota and archaea. The GntR family has over 6000 members distributed among almost all bacterial species, which is comprised of FadR, HutC, MocR, YtrA, AraR, PlmA, and other subfamilies for the regulation of the most varied biological process. The monomeric proteins of the GntR family are characterized by two function domains: a small highly conserved winged helix-turn-helix prokaryotic DNA binding domain in the N-terminus, and a very diverse regulatory ligand-binding domain in the C-terminus for effector-binding/oligomerization, which provides the basis for the subfamily classifications. Binding of the effector to GntR-like transcriptional regulators is presumed to result in a conformational change that regulates the DNA-binding affinity of the repressor. The GntR-like proteins bind as dimers, where each monomer recognizes a half-site of 2-fold symmetric DNA sequences.
Pssm-ID: 153418 [Multi-domain] Cd Length: 66 Bit Score: 96.75 E-value: 3.24e-26
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446494717 12 PLYKQLEDALKEAIARGEYKPGQQIPTENELSVRWQVSRVTVRKALDALTRENLLTRVSGKGTFVS 77
Cdd:cd07377 1 PLYEQIADQLREAILSGELKPGDRLPSERELAEELGVSRTTVREALRELEAEGLVERRPGRGTFVA 66
|
|
| PRK09764 |
PRK09764 |
GntR family transcriptional regulator; |
9-239 |
4.74e-26 |
|
GntR family transcriptional regulator;
Pssm-ID: 182065 [Multi-domain] Cd Length: 240 Bit Score: 101.44 E-value: 4.74e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494717 9 SAKPLYKQLEDALKEAIARGEYKPGQQIPTENELSVRWQVSRVTVRKALDALTRENLLTRVSGKGTFVSSEKFQRSMIGI 88
Cdd:PRK09764 2 GHKPLYRQIADRIREQIARGELKPGDALPTESALQTEFGVSRVTVRQALRQLVEQQILESIQGSGTYVKEERVNYDIFQL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494717 89 MSFSElcQSQGRRPGSRTIKSVFESV--DNETKALLNMNDGEKAVVIERIRYADDVAVSLETVHLPPRFAFLLDEDLNNH 166
Cdd:PRK09764 82 TSFDE--KLSDRHVDTHSEVLIFEVIpaDDFLQQQLQITAQDRVWHVKRVRYRKQKPMALEETWMPLALFPDLTWQVMEN 159
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446494717 167 SLYECLREKHHLWFTHSRKMIELVYASFEVAHYLGVNEGYPLILIKSEMIDNKGELSCVSQQLIVGDKIRFTV 239
Cdd:PRK09764 160 SKYHFIEEVKKMVIDRSEQEIIPLMPTEEMSRLLNISQTKPILEKVSRGYLVDGRVFEYSRNAFNTDDYKFTL 232
|
|
| trehalos_R_Bsub |
TIGR02404 |
trehalose operon repressor, B. subtilis-type; This family consists of repressors of the GntR ... |
13-215 |
9.31e-24 |
|
trehalose operon repressor, B. subtilis-type; This family consists of repressors of the GntR family typically associated with trehalose utilization operons. Trehalose is imported as trehalose-6-phosphate and then hydrolyzed by alpha,alpha-phosphotrehalase to glucose and glucose-6-P. This family includes repressors mostly from Gram-positive lineages and does not include the TreR from E. coli. [Regulatory functions, DNA interactions]
Pssm-ID: 274116 [Multi-domain] Cd Length: 233 Bit Score: 95.12 E-value: 9.31e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494717 13 LYKQLEDAlkeaIARGEYKPGQQIPTENELSVRWQVSRVTVRKALDALTRENLLTRVSGKGTFV-SSEKFQRSMIGIMSF 91
Cdd:TIGR02404 5 IYQDLEQK----ITKGQYKEGDYLPSEHELMDQYGASRETVRKALNLLTERGYIQKIQGKGSIVlNRKQIEFPISGITSF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494717 92 SELCQSQGRRpgSRTIKSVFES---VDNETKALLNMNDGEKAVVIERIRYADDVAVSLETVHLPPRFAFLLDEDLNNHSL 168
Cdd:TIGR02404 81 KELNETLGLD--SKTEVVELDKedpLPETLAQLTGLEEGSLIWRIKRVRVIDGEAVILDIDYLLKELVPGLTKEIAEDSI 158
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 446494717 169 YECLREKHHLWFTHSRKMIELVYASFEVAHYLGVNEGYPLILIKSEM 215
Cdd:TIGR02404 159 YQYLENELGLAISYAQKEITVEPCTDEDKKLLDLDGDDHVVVVKSKT 205
|
|
| YhcF |
COG1725 |
DNA-binding transcriptional regulator YhcF, GntR family [Transcription]; |
6-78 |
1.13e-21 |
|
DNA-binding transcriptional regulator YhcF, GntR family [Transcription];
Pssm-ID: 441331 [Multi-domain] Cd Length: 114 Bit Score: 86.39 E-value: 1.13e-21
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446494717 6 DSKSAKPLYKQLEDALKEAIARGEYKPGQQIPTENELSVRWQVSRVTVRKALDALTRENLLTRVSGKGTFVSS 78
Cdd:COG1725 4 DFDSGVPIYEQIADQIKEAIASGELKPGDRLPSVRELAAELGVNPNTVAKAYRELEDEGLIETRRGKGTFVAE 76
|
|
| GntR |
pfam00392 |
Bacterial regulatory proteins, gntR family; This family of regulatory proteins consists of the ... |
13-76 |
2.88e-21 |
|
Bacterial regulatory proteins, gntR family; This family of regulatory proteins consists of the N-terminal HTH region of GntR-like bacterial transcription factors. At the C-terminus there is usually an effector-binding/oligomerization domain. The GntR-like proteins include the following sub-families: MocR, YtrR, FadR, AraR, HutC and PlmA, DevA, DasR. Many of these proteins have been shown experimentally to be autoregulatory, enabling the prediction of operator sites and the discovery of cis/trans relationships. The DasR regulator has been shown to be a global regulator of primary metabolism and development in Streptomyces coelicolor.
Pssm-ID: 306822 [Multi-domain] Cd Length: 64 Bit Score: 83.82 E-value: 2.88e-21
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446494717 13 LYKQLEDALKEAIARGEYKPGQQIPTENELSVRWQVSRVTVRKALDALTRENLLTRVSGKGTFV 76
Cdd:pfam00392 1 LYEQVYARLREDILSGRLRPGDKLPSERELAAEFGVSRTTVREALRRLEAEGLVERRQGRGTFV 64
|
|
| ARO8 |
COG1167 |
DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain ... |
1-78 |
4.31e-20 |
|
DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain [Transcription, Amino acid transport and metabolism]; DNA-binding transcriptional regulator, MocR family, contains an aminotransferase domain is part of the Pathway/BioSystem: Lysine biosynthesis
Pssm-ID: 440781 [Multi-domain] Cd Length: 471 Bit Score: 88.35 E-value: 4.31e-20
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446494717 1 MIEQPDSKSAKPLYKQLEDALKEAIARGEYKPGQQIPTENELSVRWQVSRVTVRKALDALTRENLLTRVSGKGTFVSS 78
Cdd:COG1167 1 MLIRLDRDSSGPLYLQLADALREAILSGRLPPGDRLPSSRELAAQLGVSRSTVVRAYEELEAEGLIESRPGSGTFVAA 78
|
|
| FadR |
COG2186 |
DNA-binding transcriptional regulator, FadR family [Transcription]; |
9-78 |
5.11e-20 |
|
DNA-binding transcriptional regulator, FadR family [Transcription];
Pssm-ID: 441789 [Multi-domain] Cd Length: 232 Bit Score: 84.99 E-value: 5.11e-20
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494717 9 SAKPLYKQLEDALKEAIARGEYKPGQQIPTENELSVRWQVSRVTVRKALDALTRENLLTRVSGKGTFVSS 78
Cdd:COG2186 4 RRRSLAEQVAEQLRELILSGELKPGDRLPSERELAEQLGVSRTTVREALRALEALGLVEVRQGGGTFVRE 73
|
|
| PRK14999 |
PRK14999 |
histidine utilization repressor; Provisional |
1-212 |
5.13e-19 |
|
histidine utilization repressor; Provisional
Pssm-ID: 184961 [Multi-domain] Cd Length: 241 Bit Score: 82.67 E-value: 5.13e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494717 1 MIEQPDSKSAKPLYKQLEDALKEAIARGEYKPGQQIPTENELSVRWQVSRVTVRKALDALTRENLLTRVSGKGTFVSSEK 80
Cdd:PRK14999 1 MYSSRSRSAPAPFYETVKQDICKKIAGGVWQPHDRIPSEAELVAQYGFSRMTINRALRELTDEGWLVRLQGVGTFVAEPK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494717 81 FQRSMIGIMSFSElcQSQGRRPGSRTIKSVFESV--DNETKALLNMNDGEKAVVIERIRYADDVAVSLE----TVHLPPR 154
Cdd:PRK14999 81 GQSALFEVRSIAE--EIAARRHQHRCEVLTLERVraNAIQASALNVNESDVIFHSIMVHYENDLPVQIEdrcvNADIAVD 158
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 446494717 155 FaflLDEDLNNHSLYECLREKHHLwfTHSRKMIELVYASFEVAHYLGVNEGYPLILIK 212
Cdd:PRK14999 159 Y---LTQDYRQTTPHAYLSRIAPL--TEGEHIVEAVRATAQECAWLTIKEHEPCLLIR 211
|
|
| HTH_GNTR |
smart00345 |
helix_turn_helix gluconate operon transcriptional repressor; |
17-76 |
1.19e-18 |
|
helix_turn_helix gluconate operon transcriptional repressor;
Pssm-ID: 197669 [Multi-domain] Cd Length: 60 Bit Score: 76.84 E-value: 1.19e-18
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494717 17 LEDALKEAIARGEYKPGQQIPTENELSVRWQVSRVTVRKALDALTRENLLTRVSGKGTFV 76
Cdd:smart00345 1 VAERLREDIVSGELRPGDKLPSERELAAQLGVSRTTVREALSRLEAEGLVQRRPGSGTFV 60
|
|
| GntR |
COG1802 |
DNA-binding transcriptional regulator, GntR family [Transcription]; |
4-78 |
3.03e-14 |
|
DNA-binding transcriptional regulator, GntR family [Transcription];
Pssm-ID: 441407 [Multi-domain] Cd Length: 222 Bit Score: 69.18 E-value: 3.03e-14
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446494717 4 QPDSKSAKPLYKQLEDALKEAIARGEYKPGQQIpTENELSVRWQVSRVTVRKALDALTRENLLTRVSGKGTFVSS 78
Cdd:COG1802 3 SPSPLRRESLAEQVYEALREAILSGELPPGERL-SEAELAERLGVSRTPVREALRRLEAEGLVEIRPNRGARVAP 76
|
|
| PRK10079 |
PRK10079 |
phosphonate metabolism transcriptional regulator PhnF; Provisional |
16-239 |
1.15e-13 |
|
phosphonate metabolism transcriptional regulator PhnF; Provisional
Pssm-ID: 182227 [Multi-domain] Cd Length: 241 Bit Score: 67.88 E-value: 1.15e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494717 16 QLEDALkeaiaRGEYKPGQQIPTENELSVRWQVSRVTVRKALDALTRENLLTRVSGKGTFVSSEKFQRSMIGIMSFSELC 95
Cdd:PRK10079 20 KLEQEL-----RQHYRCGDYLPAEQQLAARYEVNRHTLRRAIDQLVEKGWVQRRQGVGVLVLMRPYDYPLNAQARFSQNL 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494717 96 QSQGRRPGSRTIKSVFESVDNETKALLNMNDGEKAVVIERIRYADDVAVSLETVHLPPRFAFLLDEDLNNHSLYECLREK 175
Cdd:PRK10079 95 LDQGSHPTSEKLLSVLRPASGHVADALGITEGENVIHLRTLRRVNGVALCLIDHYFADLTWWPTLQRFDSGSLHDFLREQ 174
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446494717 176 HHLWFTHSRKMIELVYASFEVAHYLGVNEGYPLILIKS-EMIDNKGELSCVSQQLIVGDKIRFTV 239
Cdd:PRK10079 175 LGIALRRSQTRISARRAQAKESQLLEIPNMSPLLCVRTlNHRDGESSPAEYSVSLTRADMIEFTM 239
|
|
| pdhR |
PRK09464 |
pyruvate dehydrogenase complex transcriptional repressor PdhR; |
2-93 |
1.98e-09 |
|
pyruvate dehydrogenase complex transcriptional repressor PdhR;
Pssm-ID: 181879 [Multi-domain] Cd Length: 254 Bit Score: 56.18 E-value: 1.98e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494717 2 IEQPdsKSAKPLYKQLEdalkEAIARGEYKPGQQIPTENELSVRWQVSRVTVRKALDALTRENLLTRVSGKGTFVSSEKF 81
Cdd:PRK09464 6 IRQP--KLSDVIEQQLE----FLILEGTLRPGEKLPPERELAKQFDVSRPSLREAIQRLEAKGLLLRRQGGGTFVQSSLW 79
|
90
....*....|..
gi 446494717 82 QrsmigimSFSE 93
Cdd:PRK09464 80 Q-------SFSD 84
|
|
| PRK03837 |
PRK03837 |
transcriptional regulator NanR; Provisional |
1-77 |
2.54e-09 |
|
transcriptional regulator NanR; Provisional
Pssm-ID: 235166 [Multi-domain] Cd Length: 241 Bit Score: 55.80 E-value: 2.54e-09
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446494717 1 MIEQPDSKSAKPLYKQLEDALKEAIARGEYKPGQQIPTENELSVRWQVSRVTVRKALDALTRENLLTRVSGKGTFVS 77
Cdd:PRK03837 2 RNLRSRPIARKKLSEEVEERLEQMIRSGEFGPGDQLPSERELMAFFGVGRPAVREALQALKRKGLVQISHGERARVS 78
|
|
| PRK10225 |
PRK10225 |
Uxu operon transcriptional regulator; |
6-99 |
1.18e-07 |
|
Uxu operon transcriptional regulator;
Pssm-ID: 182318 [Multi-domain] Cd Length: 257 Bit Score: 51.17 E-value: 1.18e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494717 6 DSKSAKPLYKQLEDALKEAIARGEYKPGQQIPTENELSVRWQVSRVTVRKALDALTRENLLTRVSGKGTFVSSEKFQRSM 85
Cdd:PRK10225 3 SATSAQRPYQEVGAMIRDLIIKTPYNPGERLPPEREIAEMLDVTRTVVREALIMLEIKGLVEVRRGAGIYVLDSSGSHNT 82
|
90
....*....|....
gi 446494717 86 IGIMsfSELCQSQG 99
Cdd:PRK10225 83 DSPD--ANVCNDAG 94
|
|
| PRK10421 |
PRK10421 |
DNA-binding transcriptional repressor LldR; Provisional |
11-79 |
5.94e-07 |
|
DNA-binding transcriptional repressor LldR; Provisional
Pssm-ID: 236690 [Multi-domain] Cd Length: 253 Bit Score: 49.00 E-value: 5.94e-07
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446494717 11 KPLYKQLEDALKEAIARGEYKPGQQIPTENELSVRWQVSRVTVRKALDALTRENLLTRVSGKGTFVSSE 79
Cdd:PRK10421 1 RRLSDEVADRVRALIEEKNLEAGMKLPAERQLAMQLGVSRNSLREALAKLVSEGVLLSRRGGGTFIRWR 69
|
|
| PRK11523 |
PRK11523 |
transcriptional regulator ExuR; |
13-78 |
1.64e-04 |
|
transcriptional regulator ExuR;
Pssm-ID: 183176 [Multi-domain] Cd Length: 253 Bit Score: 41.75 E-value: 1.64e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446494717 13 LYKQLEDALKEAIARGEYKPGQQIPTENELSVRWQVSRVTVRKALDALTRENLLTRVSGKGTFVSS 78
Cdd:PRK11523 9 LYQQLAAELKERIEQGVYLVGDKLPAERFIADEKNVSRTVVREAIIMLEVEGYVEVRKGSGIHVVS 74
|
|
| PRK09990 |
PRK09990 |
DNA-binding transcriptional regulator GlcC; Provisional |
15-154 |
4.83e-04 |
|
DNA-binding transcriptional regulator GlcC; Provisional
Pssm-ID: 182186 [Multi-domain] Cd Length: 251 Bit Score: 40.13 E-value: 4.83e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446494717 15 KQLEDALKEAIAR----GEYKPGQQIPTENELSVRWQVSRVTVRKALDALTRENLLTRVSGKGTFVSSEKFQRSMIGIMs 90
Cdd:PRK09990 6 RPIADVVAERIERlivdGVLKVGQALPSERRLCEKLGFSRSALREGLTVLRGRGIIETAQGRGSFVARLNRVQDASPLM- 84
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446494717 91 fsELCQSQgrrpgSRTIKSVFesvdnETKALLnmnDGEKA------------VVIERiRYADDVAVSLETVHLPPR 154
Cdd:PRK09990 85 --HLFSSQ-----PRTLYDLL-----EVRALL---EGESArlaalrgtqadfVLITR-RYEEMLAAHENNKEIDPI 144
|
|
| GlpR |
COG1349 |
DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family [Transcription, ... |
40-85 |
7.14e-04 |
|
DNA-binding transcriptional regulator of sugar metabolism, DeoR/GlpR family [Transcription, Carbohydrate transport and metabolism];
Pssm-ID: 440960 [Multi-domain] Cd Length: 254 Bit Score: 39.73 E-value: 7.14e-04
10 20 30 40
....*....|....*....|....*....|....*....|....*.
gi 446494717 40 NELSVRWQVSRVTVRKALDALTRENLLTRVSGKGTFVSSEKFQRSM 85
Cdd:COG1349 23 EELAERLGVSEETIRRDLAELEEQGLLRRVHGGAVLVSSAAAEPPF 68
|
|
| |
