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MULTISPECIES: autotransporter YejO [Escherichia]
Protein Classification
autotransporter outer membrane beta-barrel domain-containing protein ( domain architecture ID 11465958 )
autotransporter outer membrane beta-barrel domain-containing protein may function as an adhesin that mediates bacterial attachment to host cells, and may play a role in virulence
List of domain hits
Name
Accession
Description
Interval
E-value
autotrans_barl
TIGR01414 outer membrane autotransporter barrel domain; A number of Gram-negative bacterial proteins, ...
468-863
1.21e-104
outer membrane autotransporter barrel domain; A number of Gram-negative bacterial proteins, mostly found in pathogens and associated with virulence, contain a conserved C-terminal domain that integrates into the outer membrane and enables the N-terminal region to be delivered across the membrane. This C-terminal autotransporter domain is about 400 amino acids in length and includes the aromatic amino acid-rich OMP signal, typically ending with a Phe or Trp residue, at the extreme C-terminus. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis]
Pssm-ID: 273608 [Multi-domain]
Cd Length: 431
Bit Score: 330.11
E-value: 1.21e-104
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 468 S GNG N F Y M R TD MA -- N H Q S D Q L N V T G Q A T G DFKIF V TDT G ASP A A - GD SL TLVT T - GG G DAAFTL G N ag G V VD I G T Y E YT 543
Cdd:TIGR01414 15 T GNG G F V M N TD LG gd N S Q T D R L V V N G N A S G TTGVV V NNI G GEG A Q t GD GI TLVT V n GG S DAAFTL A N -- G K VD A G A Y T YT 92
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 544 L LD NG --- N HS W S L AENRAQI TP STTDV --------- LNM A A A QPLV F D AELDT V R E R L G SVKGVSY D TA -- M W SSAINT 609
Cdd:TIGR01414 93 L YK NG ted N NN W Y L TSSLPDL TP PGQQL sptyraeag SYA A N A NAAL F L AELDT L R Q R M G DLRSAAR D AG ng V W ARIFGG 172
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 610 R N NVTT DAG - AG FE Q TL TG LT LG I D SRFSR - EESSTIR GL FF GY SHS DI GFD --- R GGKG N VD S Y T LG A Y AG W EHQN GAY 684
Cdd:TIGR01414 173 D N HLDG DAG a AG YD Q NT TG VQ LG G D ILLAG n ADGDLHV GL MA GY AKA DI KTR syk Y GGKG K VD G Y G LG L Y GT W LQDS GAY 252
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 685 VDGV VKVD RF A N TIHGKM SNG a TAF G D Y S SNG AG A HV E S G F R W -- VDGL W S V R P YLAFTG F TTD G Q DY TL SNG M R ADV G N 762
Cdd:TIGR01414 253 VDGV LQYS RF R N DVSSTG SNG - KVS G K Y N SNG FT A SL E A G Y R Y nl GGNG W Y V E P QAQLSY F GVS G D DY KE SNG T R VLG G G 331
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 763 TRI L RAEA G TA V S Y HM DL QN G TTLE P W LKA A V RQ E YADSNQ V K VN DD g KFN ND VA GTR GV Y QA G IRSSFTPT LS GHLS V S 842
Cdd:TIGR01414 332 GDS L QGRL G LR V G Y QF DL GT G RAVK P Y LKA N V LH E FKGGTG V R VN GV - TIR ND FS GTR AE Y GV G VNAKIKDN LS LYAD V D 410
410 420
....*....|....*....|.
gi 446476363 843 Y GN G AGVESPWNTQA GV VWT F 863
Cdd:TIGR01414 411 Y QK G GKKYTDNQGNL GV RYS F 431
AidA super family
cl34620 Autotransporter adhesin AidA [Cell wall/membrane/envelope biogenesis, Intracellular ...
71-863
1.92e-48
Autotransporter adhesin AidA [Cell wall/membrane/envelope biogenesis, Intracellular trafficking, secretion, and vesicular transport];
COG3468 :Pssm-ID: 442691 [Multi-domain]
Cd Length: 846
Bit Score: 185.15
E-value: 1.92e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 71 G ISSNTEIN GG YQYIEMNGTAEY S VLND G YQIVQM GG AANQTTLNN G VLQVYGAANEPTIK GG RLIIEKD G ITVFAAIEK 150
Cdd:COG3468 58 G GGGGAGGG GG GAGSGGGLAGAG S GGTG G NSTGGG GG NSGTGGTGG G GGGGGSGNGGGGGG GG GGGGTGG G GGGGTGSAG 137
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 151 GG LLEVKE G GLAFAVDQK A G G AIKTTTRAMEVF G TNRL G QFDIKD G IANNMLLENG G SLRVEENDFAYNTTVDS GG L le V 230
Cdd:COG3468 138 GG GGGGGG G TGVGGTGAA A A G GGTGSGGGGSGG G GGAG G GGGGGA G GSGGAGSTGS G AGGGGGGSGGGGGAAGT GG G -- G 215
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 231 MD GG T A T G VDKK AG GKLIVSTNALEVS G TNSKGQFSIKD G VSKNYELDD G S G LIVMEDTQAIDTILDEHATMQSLGKD TG 310
Cdd:COG3468 216 GG GG G A G G ATGG AG SGGNTGGGVGGGG G SAGGTGGGGLT G GGAAGTGGG G G G TGTGSGGGGGGGANGGGSGGGGGASG TG 295
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 311 TRVQ A NAVYDL G RSDQ NG SITYSSKAISENMVINN G RANVWA G TMVNVSVR G ND G IL evmkpqinyapaml V G KVVVSE G 390
Cdd:COG3468 296 GGGT A STGGGG G GGGG NG GGGGGGSNAGGGSGGGG G GGGGGG G GGTTLNGA G SA G GG -------------- T G AALAGT G 361
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 391 A S LRTH G AVDT S KADVSLENSAWTIIA D ITT T NQN T PLNLA N LAMSGANVIMMAEPV T RSSV T ASAENF ttlttntl SG N 470
Cdd:COG3468 362 G S GSGG G GGGG S GGGGGAGGGGANTGS D GVG T GLT T GGTGN N GGGGVGGGGGGGLTL T GGTL T VNGNYT -------- GN N 433
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 471 G NFYMR T DMANHQ S -- D Q L N V T G QAT G DFKIF V TDT G ASP A A - GDSLTL V TTG G G - D A AFTLG NA ggv V DI G T YEYTL -- 544
Cdd:COG3468 434 G TLVLN T VLGDDN S pt D R L V V N G NTS G TTGVR V NNA G GLG A Q t VNGIEV V EVN G A s D G AFTLG GR --- V VA G A YEYTL yq 510
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 545 -- LDNGNHS W S L ------- AENRAQIT P STTDV L NMA AA qp LVFDA EL D T VRE RLG ---- SVK G V S YDTAM W SSAINTR N 611
Cdd:COG3468 511 gg SGGDDGN W Y L rstltpp DPPTPVYR P EVPSY L ANP AA -- ANGLF EL G T LHD RLG erry TDT G E S DNSGA W LRVEGGH N 588
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 612 NVTTDA G - AGFEQTLT GL T LG I D SRFSREESSTIR - G LFF GY SHS D I ---- GFDRG GKG N VD S Y T LG A Y AG W EHQ NG A YV 685
Cdd:COG3468 589 RSRDSS G q LDYDSNRY GL Q LG G D LLQWEDGGGRLH v G VMA GY GNG D S dvrs RATGT GKG D VD G Y S LG L Y GT W YGN NG F YV 668
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 686 DGV VKVDR F A N TIHGKMSN G A T af G D Y SS NG AG A HV E S G FRW - VDGL WS VR P YLAFTGFTT D GQ D Y T L SNG M R ADVGNTR 764
Cdd:COG3468 669 DGV LQYSW F D N DVSSDDLG G V T -- G S Y DG NG YS A SL E A G YPF k LGEG WS LE P QAQLIYQGV D FD D F T D SNG T R VSGDDGD 746
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 765 I L RAEA G TAVS Y HMDLQN G TT L E P W L K A AVRQ E YADS N Q V K VN DD g K F NN D VA GT R G VYQA G IRSSFTPT LS GHLS V S Y - 843
Cdd:COG3468 747 S L QGRL G LRLG Y EFHWDD G RA L Q P Y L E A NWLH E FLGD N S V T VN GV - S F SQ D GS GT W G ELGL G VTGQLNKN LS LYGD V G Y q 825
810 820
....*....|....*....|.
gi 446476363 844 - G NGAGVE S PWNTQA GV VWT F 863
Cdd:COG3468 826 t G LDGYDS S DTSGNL GV RYS F 846
Name
Accession
Description
Interval
E-value
autotrans_barl
TIGR01414 outer membrane autotransporter barrel domain; A number of Gram-negative bacterial proteins, ...
468-863
1.21e-104
outer membrane autotransporter barrel domain; A number of Gram-negative bacterial proteins, mostly found in pathogens and associated with virulence, contain a conserved C-terminal domain that integrates into the outer membrane and enables the N-terminal region to be delivered across the membrane. This C-terminal autotransporter domain is about 400 amino acids in length and includes the aromatic amino acid-rich OMP signal, typically ending with a Phe or Trp residue, at the extreme C-terminus. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis]
Pssm-ID: 273608 [Multi-domain]
Cd Length: 431
Bit Score: 330.11
E-value: 1.21e-104
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 468 S GNG N F Y M R TD MA -- N H Q S D Q L N V T G Q A T G DFKIF V TDT G ASP A A - GD SL TLVT T - GG G DAAFTL G N ag G V VD I G T Y E YT 543
Cdd:TIGR01414 15 T GNG G F V M N TD LG gd N S Q T D R L V V N G N A S G TTGVV V NNI G GEG A Q t GD GI TLVT V n GG S DAAFTL A N -- G K VD A G A Y T YT 92
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 544 L LD NG --- N HS W S L AENRAQI TP STTDV --------- LNM A A A QPLV F D AELDT V R E R L G SVKGVSY D TA -- M W SSAINT 609
Cdd:TIGR01414 93 L YK NG ted N NN W Y L TSSLPDL TP PGQQL sptyraeag SYA A N A NAAL F L AELDT L R Q R M G DLRSAAR D AG ng V W ARIFGG 172
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 610 R N NVTT DAG - AG FE Q TL TG LT LG I D SRFSR - EESSTIR GL FF GY SHS DI GFD --- R GGKG N VD S Y T LG A Y AG W EHQN GAY 684
Cdd:TIGR01414 173 D N HLDG DAG a AG YD Q NT TG VQ LG G D ILLAG n ADGDLHV GL MA GY AKA DI KTR syk Y GGKG K VD G Y G LG L Y GT W LQDS GAY 252
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 685 VDGV VKVD RF A N TIHGKM SNG a TAF G D Y S SNG AG A HV E S G F R W -- VDGL W S V R P YLAFTG F TTD G Q DY TL SNG M R ADV G N 762
Cdd:TIGR01414 253 VDGV LQYS RF R N DVSSTG SNG - KVS G K Y N SNG FT A SL E A G Y R Y nl GGNG W Y V E P QAQLSY F GVS G D DY KE SNG T R VLG G G 331
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 763 TRI L RAEA G TA V S Y HM DL QN G TTLE P W LKA A V RQ E YADSNQ V K VN DD g KFN ND VA GTR GV Y QA G IRSSFTPT LS GHLS V S 842
Cdd:TIGR01414 332 GDS L QGRL G LR V G Y QF DL GT G RAVK P Y LKA N V LH E FKGGTG V R VN GV - TIR ND FS GTR AE Y GV G VNAKIKDN LS LYAD V D 410
410 420
....*....|....*....|.
gi 446476363 843 Y GN G AGVESPWNTQA GV VWT F 863
Cdd:TIGR01414 411 Y QK G GKKYTDNQGNL GV RYS F 431
AidA
COG3468 Autotransporter adhesin AidA [Cell wall/membrane/envelope biogenesis, Intracellular ...
71-863
1.92e-48
Autotransporter adhesin AidA [Cell wall/membrane/envelope biogenesis, Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 442691 [Multi-domain]
Cd Length: 846
Bit Score: 185.15
E-value: 1.92e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 71 G ISSNTEIN GG YQYIEMNGTAEY S VLND G YQIVQM GG AANQTTLNN G VLQVYGAANEPTIK GG RLIIEKD G ITVFAAIEK 150
Cdd:COG3468 58 G GGGGAGGG GG GAGSGGGLAGAG S GGTG G NSTGGG GG NSGTGGTGG G GGGGGSGNGGGGGG GG GGGGTGG G GGGGTGSAG 137
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 151 GG LLEVKE G GLAFAVDQK A G G AIKTTTRAMEVF G TNRL G QFDIKD G IANNMLLENG G SLRVEENDFAYNTTVDS GG L le V 230
Cdd:COG3468 138 GG GGGGGG G TGVGGTGAA A A G GGTGSGGGGSGG G GGAG G GGGGGA G GSGGAGSTGS G AGGGGGGSGGGGGAAGT GG G -- G 215
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 231 MD GG T A T G VDKK AG GKLIVSTNALEVS G TNSKGQFSIKD G VSKNYELDD G S G LIVMEDTQAIDTILDEHATMQSLGKD TG 310
Cdd:COG3468 216 GG GG G A G G ATGG AG SGGNTGGGVGGGG G SAGGTGGGGLT G GGAAGTGGG G G G TGTGSGGGGGGGANGGGSGGGGGASG TG 295
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 311 TRVQ A NAVYDL G RSDQ NG SITYSSKAISENMVINN G RANVWA G TMVNVSVR G ND G IL evmkpqinyapaml V G KVVVSE G 390
Cdd:COG3468 296 GGGT A STGGGG G GGGG NG GGGGGGSNAGGGSGGGG G GGGGGG G GGTTLNGA G SA G GG -------------- T G AALAGT G 361
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 391 A S LRTH G AVDT S KADVSLENSAWTIIA D ITT T NQN T PLNLA N LAMSGANVIMMAEPV T RSSV T ASAENF ttlttntl SG N 470
Cdd:COG3468 362 G S GSGG G GGGG S GGGGGAGGGGANTGS D GVG T GLT T GGTGN N GGGGVGGGGGGGLTL T GGTL T VNGNYT -------- GN N 433
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 471 G NFYMR T DMANHQ S -- D Q L N V T G QAT G DFKIF V TDT G ASP A A - GDSLTL V TTG G G - D A AFTLG NA ggv V DI G T YEYTL -- 544
Cdd:COG3468 434 G TLVLN T VLGDDN S pt D R L V V N G NTS G TTGVR V NNA G GLG A Q t VNGIEV V EVN G A s D G AFTLG GR --- V VA G A YEYTL yq 510
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 545 -- LDNGNHS W S L ------- AENRAQIT P STTDV L NMA AA qp LVFDA EL D T VRE RLG ---- SVK G V S YDTAM W SSAINTR N 611
Cdd:COG3468 511 gg SGGDDGN W Y L rstltpp DPPTPVYR P EVPSY L ANP AA -- ANGLF EL G T LHD RLG erry TDT G E S DNSGA W LRVEGGH N 588
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 612 NVTTDA G - AGFEQTLT GL T LG I D SRFSREESSTIR - G LFF GY SHS D I ---- GFDRG GKG N VD S Y T LG A Y AG W EHQ NG A YV 685
Cdd:COG3468 589 RSRDSS G q LDYDSNRY GL Q LG G D LLQWEDGGGRLH v G VMA GY GNG D S dvrs RATGT GKG D VD G Y S LG L Y GT W YGN NG F YV 668
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 686 DGV VKVDR F A N TIHGKMSN G A T af G D Y SS NG AG A HV E S G FRW - VDGL WS VR P YLAFTGFTT D GQ D Y T L SNG M R ADVGNTR 764
Cdd:COG3468 669 DGV LQYSW F D N DVSSDDLG G V T -- G S Y DG NG YS A SL E A G YPF k LGEG WS LE P QAQLIYQGV D FD D F T D SNG T R VSGDDGD 746
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 765 I L RAEA G TAVS Y HMDLQN G TT L E P W L K A AVRQ E YADS N Q V K VN DD g K F NN D VA GT R G VYQA G IRSSFTPT LS GHLS V S Y - 843
Cdd:COG3468 747 S L QGRL G LRLG Y EFHWDD G RA L Q P Y L E A NWLH E FLGD N S V T VN GV - S F SQ D GS GT W G ELGL G VTGQLNKN LS LYGD V G Y q 825
810 820
....*....|....*....|.
gi 446476363 844 - G NGAGVE S PWNTQA GV VWT F 863
Cdd:COG3468 826 t G LDGYDS S DTSGNL GV RYS F 846
auto_BafA_Cterm
NF040482 BafA family autotransporter C-terminal domain; BafA from both Bartonella henselae and ...
306-846
2.38e-47
BafA family autotransporter C-terminal domain; BafA from both Bartonella henselae and Bartonella quintana, and possibly all Bartonella BafA, are mitogenic autotransporter virulence factors that help induce vasoproliferative lesions during infection. This HMM represents the more conserved C-terminal portion only, as the passenger region is more highly variable in length and sequence.
Pssm-ID: 468508 [Multi-domain]
Cd Length: 617
Bit Score: 179.07
E-value: 2.38e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 306 G KDTG T R V QANA V YDLGRSD Q N gsi TYSSKAISENM V INN G RAN V W AG TMV n VS V RG N DGILEVMKP ------- Q IN --- 375
Cdd:NF040482 30 G IAWN T K V MQGG V QNVAKKS Q S --- AKNGGFAFNTE V FGG G KQR V L AG GKA - IG V TL N ETAVQEIYA ggfvknl T IN dea 105
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 376 ---- YA P A M L V GK VV V SEGAS L RTHGAV D --- T SKA D VS L -- ENSAWTI I A D ITTTNQNTPLN L anlam SG ANVIMM A ep 446
Cdd:NF040482 106 kswv YA G A T L E GK TL V NHSGQ L YLYAGD D khh T TVE D II L ng RDTKLYS I V D EFDGKSSLIQK L ----- SG EGSVIF A -- 178
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 447 vtrss V T A S AENFTT L TT N T LSG NGN F YMR T DM A NHQS D Q L NV t GQAT G DFK I F V T D T G A -- SPAAGDSLT L V T TGG G D A 524
Cdd:NF040482 179 ----- S T G S DPYYSQ L HV N N LSG SLH F KFN T SI A GNRG D Y L FI - ENGK G NHT I S V A D S G V ei TDPFSNKRD L I T DQS G G A 252
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 525 A FTL G N AG G ---- V VD I GTY E Y T L --- L D NGNHS W S L AEN R AQ ------------------- I TPST TD VL N MA A A QP L V 578
Cdd:NF040482 253 N FTL T N LS G ekin A VD G GTY M Y G L kqr K D ENGKI W Y L SAD R IS gqessspdpseplsvsdfl T TPST DA VL S MA V A PG L I 332
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 579 F DA EL D TVR ERL G SVKGVSYD TA M W SS AI NTRNNVT T DA g AG F EQTL TG LT LG I D SRFSREESSTIR G L F FG Y SHSD I GF 658
Cdd:NF040482 333 F NN EL Q TVR TGR G ILDRNKKN TA L W TY AI KSKERIA T GH - TH F KLEQ TG IV LG A D GLSELTHGDLYI G G F GS Y DQAR I AH 411
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 659 D RGG KGNVDS Y TL GAYA GWEHQN G A Y V DG VV K VDRFA N TIHGKMS NG ATAF GDY SSNGA G AHV E S G F R WVDGLWS - VR PY 737
Cdd:NF040482 412 A RGG VSDINT Y SI GAYA TYFDHR G W Y L DG IL K YNYYQ N NLKAVST NG LAIQ GDY NQWAI G TSF E A G Y R FETAQNT w MQ PY 491
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 738 LAF T GFTTD G QDYT LSNGM RA D VGNTRI LR A E A G TAVSYHMDLQNG T T L EPWLK AA VRQ E YA D S N QVKV N DDG KF NN D VA 817
Cdd:NF040482 492 GQL T WLQVE G KKIK LSNGM TG D ISPSTS LR S E V G LSAGHEFIVGAE T S L TAYIT AA WLR E NI D N N HTTI N KQH KF IT D LS 571
570 580
....*....|....*....|....*....
gi 446476363 818 G TR G VYQA G IR S SFTPT L SGHLSVS Y GN G 846
Cdd:NF040482 572 G NA G KLGI G LN S FVSDK L TLYAEAH Y LK G 600
Pertactin
pfam03212 Pertactin;
430-556
2.39e-39
Pertactin;
Pssm-ID: 460848 [Multi-domain]
Cd Length: 121
Bit Score: 141.76
E-value: 2.39e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 430 L A N LA M SG AN V IM maepvtr S S VTAS A EN F T TLTT N TLSG N G N F Y M RT D M A NHQS DQL N V T G Q A T G DFKIF V TD TG AS PA 509
Cdd:pfam03212 1 V A A LA L SG GT V DF ------- A S PAEP A GA F K TLTT Q TLSG S G T F V M NA D V A SGTG DQL V V S G N A S G QHVLL V RN TG SE PA 73
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 446476363 510 A G DS - LTLV T TGGGDAAFTLGN A GG V VD I GTY E Y T L LDN GN HS WSL AE 556
Cdd:pfam03212 74 S G NT k LTLV E TGGGDAAFTLGN K GG K VD A GTY R Y R L TAD GN GN WSL TA 121
PL1_Passenger_AT
cd01343 Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 1, of ...
302-561
4.62e-38
Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 1, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of Neisseria and Haemophilus IgA1 proteases, SPATEs (serine protease autotransporters secreted by Enterobacteriaceae), Bordetella pertacins, and nonprotease autotransporters, TibA and similar AIDA-like proteins.
Pssm-ID: 238653 [Multi-domain]
Cd Length: 233
Bit Score: 142.11
E-value: 4.62e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 302 MQSLGKDTGTRVQA NA VYD LG RS - DQNG S I T YSSK A -- ISE N MVINNGRAN vwa G T MVNVSV RG N dgi LEVMKP Q INY A P 378
Cdd:cd01343 1 GRLVSDGGNITAGD NA QLT LG GG a LYGS S V T LTNG A vl DAG N ANLSAAASY --- A T LSGSNI RG T --- VVLGAG Q PLQ A L 74
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 379 A mlvg KVVVSEG A SL rt H GA VDTSK A D VSL E - NS A WT IIA D I tttnqntpl N LA NL AMS G AN V IMMAEPVTR - SSV T A sa 456
Cdd:cd01343 75 A ---- ELLLGGN A AW -- T GA IQGLN A T VSL N l NS V WT LTG D S --------- N VN NL TLN G GT V DFNGPSAGK f NTL T V -- 137
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 457 enfttltt NTLSGNG N F Y MRTD M A NH Q S D Q L N VTG Q ATGDF KIF V TD TG AS P AA G DS LTLV T T G - GGDA A FTL G N ag G V V 535
Cdd:cd01343 138 -------- NTLSGNG T F V MRTD L A GG Q G D K L V VTG S ATGDF NLL V VN TG KE P TS G LN LTLV S T P k GGDA E FTL A N -- G T V 207
250 260
....*....|....*....|....*.
gi 446476363 536 D I G T Y E YTL LDN GN HS W S L AENRAQI 561
Cdd:cd01343 208 D L G A Y R YTL VKD GN GN W T L TGPKKES 233
Autotransporter
smart00869 Autotransporter beta-domain; Secretion of protein products occurs by a number of different ...
608-846
2.45e-30
Autotransporter beta-domain; Secretion of protein products occurs by a number of different pathways in bacteria. One of these pathways known as the type IV pathway was first described for the IgA1 protease. The protein component that mediates secretion through the outer membrane is contained within the secreted protein itself, hence the proteins secreted in this way are called autotransporters. This family corresponds to the presumed integral membrane beta-barrel domain that transports the protein. This domain is found at the C-terminus of the proteins it occurs in. The N-terminus contains the variable passenger domain that is translocated across the membrane. Once the passenger domain is exported it is cleaved auto-catalytically in some proteins, in others a different peptidase is used and in some cases no cleavage occurs.
Pssm-ID: 214872 [Multi-domain]
Cd Length: 268
Bit Score: 120.75
E-value: 2.45e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 608 NTRNNVTTDAG AGF EQTLT GL T LG I D S R F S r EESSTIR G LFF GY SH S DIG F D --- RG GKG N VDSY T LG A YAG WEHQ NG A Y 684
Cdd:smart00869 8 LRQDSSGSGGS AGF DYDSY GL Q LG A D Y R L S - DNGNLSL G FAA GY GN S KVD F S gnk GS GKG D VDSY G LG L YAG YSLG NG L Y 86
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 685 V D GVVKVD R FA N TIHG K MSN G -- AT A F G D Y SSN G A GA HV E S G F R W - VD G LWSVR P YLAFTGFTTDGQDY T L S N G ---- MR 757
Cdd:smart00869 87 L D AQLGYG R SD N DTKR K VTL G ga GR A K G S Y DGT G Y GA SL E A G Y R F y LG G GLTLT P FAGLAYSRVRQDGF T E S G G gafg LS 166
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 758 A D VGNTRI L RAEA G TAVS Y HMD L QN G T TL E P W L KA A VRQEYA D S N Q V KVN ------- DDGKFNN D VAGTRGVYQA G IRSS 830
Cdd:smart00869 167 V D SQSLDS L SLPL G LRLE Y RLA L GD G A TL T P Y L RL A YVHDFY D D N P V VTA sllgsga SFTTSGT D LDRNAAELGL G LSAK 246
250
....*....|....*.
gi 446476363 831 FTPT LS GH L SVSYGN G 846
Cdd:smart00869 247 LSNG LS LS L NYDGEF G 262
PRK09945
PRK09945 hypothetical protein; Provisional
89-503
2.42e-23
hypothetical protein; Provisional
Pssm-ID: 137602 [Multi-domain]
Cd Length: 418
Bit Score: 103.64
E-value: 2.42e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 89 G TAEYSVLN DG - Y QIV QM G GAANQ T T L NN G -- VLQVY G A A NEPTIK G - G R L IIEKD GI TVFAAIEKG G L L E V KE G GL A FA 164
Cdd:PRK09945 2 G SDAKNLMS DG n V QIV KT G EVIGA T Q L TE G el IVEAG G R A ENTVVT G a G W L KVATG GI AKCTQYGNN G T L S V SD G AI A TD 81
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 165 VD Q KA GGAI KTT T R A M e V F G TNRL G Q F DIKD G I A NNM LLENGG S LRV E E NDF A YNTTV D SG G L L E V md G GT ATG V DKKA G 244
Cdd:PRK09945 82 IV Q SE GGAI SLS T L A T - V N G RHPE G E F SVDQ G Y A CGL LLENGG N LRV L E GHR A EKIIL D QE G G L L V -- N GT TSA V VVDE G 158
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 245 G K L I V STN alevsgtnskgqfsikd G VSK N Y E LDD G S gl IV M EDTQ A I DT I L DE h A TM QS L - G K D TG T R V QANAV Y D LG r 323
Cdd:PRK09945 159 G E L L V YPG ----------------- G EAS N C E INQ G G -- VF M LAGK A S DT L L AG - G TM NN L g G E D SD T I V ENGSI Y R LG - 217
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 324 sd QN G SIT YSS KA i SE N MVI N - N GRA N V W AGT MV N VSVR G NDG IL ------- E VMKPQINY AP AM L V G K V VVSE GAS LRT 395
Cdd:PRK09945 218 -- TD G LQL YSS GK - TQ N LSV N v G GRA E V H AGT LE N AVIQ G GTV IL lsptsad E NFVVEEDR AP VE L T G S V ALLD GAS MII 294
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 396 HGAV D TSKADVSLENSAWT I IADI T TTNQNTPLNLA N LAMS G ANVIMMAEPV T RSSVTAS aenfttlttn T L S G N G NFYM 475
Cdd:PRK09945 295 GYGA D LQQSTITVQQGGVL I LDGS T VKGDSVTFSVG N INLN G GKLWLITGAA T HVQLKVK ---------- R L R G E G AICL 364
410 420
....*....|....*....|....*...
gi 446476363 476 R T DMANHQS D QL NV T G QA TGD FKIFV TD 503
Cdd:PRK09945 365 Q T SAKEISP D FI NV K G EV TGD IHVEI TD 392
PL_Passenger_AT
cd00253 Pertactin-like passenger domains (virulence factors) of autotransporter proteins of the type V ...
395-554
3.66e-19
Pertactin-like passenger domains (virulence factors) of autotransporter proteins of the type V secretion system. Autotransporters are proteins used by Gram-negative bacteria to transport proteins across their outer membranes. The C-terminal (beta) domain of autotransporters forms a pore in the outer membrane through which the N-terminal passenger domain is transported. Following transport, the passenger domain is generally cleaved by an outer membrane protease with the passenger domain either remaining in contact with the surface via a noncovalent interaction with the beta domain or cleaved to release a soluble protein. These proteins are highly diverse and perform a variety of functions that promote virulence, including catalyzing proteolysis, serving as an adhesin, mediating actin-promoted motility, or serving as a cytotoxin. Proteins in this family share similarity in the C-terminal region of the passenger domain as seen in the pertactin structure P.69, a Bordetella pertussis agglutinogen responsible for human pertussis. The P.69 protein consists of a 16-stranded parallel beta-helix with a V-shaped cross-section, and is one of the largest beta-helix known to date.
Pssm-ID: 238156 [Multi-domain]
Cd Length: 186
Bit Score: 86.27
E-value: 3.66e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 395 TH G AVDTSKAD VSL ENSAWTIIADIT T T N qntplnl A NL AM SG AN V IMMAEPVTRSSV T A saenfttl TT N T L S GNG N F Y 474
Cdd:cd00253 31 WL G TLQAGGGT VSL NSNSLWTLTGDS T V N ------- G NL TN SG GT V DFGSASGAFNTL T V -------- NG N Y L G GNG T F V 95
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 475 MR TD MA -- N HQS D Q L N VTG Q A T G DFKIF V TDT G ASP A - A GD SLT LV TT - GG G DAAF T L GNA ggv VD I G T YEYTL LDN G -- 548
Cdd:cd00253 96 LN TD LG gd N SPT D K L V VTG N A S G TTNVA V VNA G GEG A s T GD GIE LV EV n GG S DAAF S L AGR --- VD A G A YEYTL YKG G vg 172
....*..
gi 446476363 549 - N HS W S L 554
Cdd:cd00253 173 n N GN W Y L 179
AIDA
pfam16168 Adhesin of bacterial autotransporter system, probable stalk; The AIDA repeat is found on ...
189-245
3.81e-16
Adhesin of bacterial autotransporter system, probable stalk; The AIDA repeat is found on bacterial autotransporter proteins. As the repeat is short and occurs multiple times, it is likely to be the region of the transporter that acts as the stalk between the beta-barrel inserted into the membrane and the N-terminal head domain.
Pssm-ID: 406554 [Multi-domain]
Cd Length: 57
Bit Score: 73.14
E-value: 3.81e-16
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*..
gi 446476363 189 G Q F D I KD G I A N N M LLENGGSL R V EENDF A YN TTVD S GG L L E V MD GGTATG VDKKA GG 245
Cdd:pfam16168 1 G A F S I SG G V A D N V LLENGGSL T V VAGTS A TD TTVD K GG T L D V QS GGTATG TVVNN GG 57
auto_AIDA-I
NF033176 autotransporter adhesin AIDA-I;
52-239
5.79e-15
autotransporter adhesin AIDA-I;
Pssm-ID: 380183 [Multi-domain]
Cd Length: 1287
Bit Score: 79.70
E-value: 5.79e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 52 G TANNTKI N PG G EQHIKEFGISSNTEING G Y QYI EMNGT A EYS V L N - D G YQI V QM GG A A NQ T T LN N G V LQ VY --- G A A NE 127
Cdd:NF033176 505 G SVSGASV N LN G RLNVFAGNVTGTILNQE G R QYI YSGAS A TST V A N n E G REY V LS GG V A DG T V LN S G G LQ AV ssg G S A SA 584
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 128 PT I - K GG RLIIEKD G ITVFAA I EK GG LLE V KE G GL A FAVDQKA GG AIK T T T R A M e V F GTN RL G Q F DIKDGI A N N ML LENG 206
Cdd:NF033176 585 TV I n E GG SQFVYEG G NVTGTV I KN GG AIR V DS G AS A LNIALSS GG NLF T S T G A T - V T GTN HY G S F SVSQNH A S N VV LENG 663
170 180 190
....*....|....*....|....*....|...
gi 446476363 207 G S L R V EENDF A YN TTV D S G G L L EVMD GG TAT G V 239
Cdd:NF033176 664 G L L A V TSGST A TD TTV N S A G R L RIDE GG ALD G T 696
auto_AIDA-I
NF033176 autotransporter adhesin AIDA-I;
27-363
1.71e-14
autotransporter adhesin AIDA-I;
Pssm-ID: 380183 [Multi-domain]
Cd Length: 1287
Bit Score: 78.16
E-value: 1.71e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 27 A L A STVEY G ETVD GVV LEKDI Q L VY -- G TAN N TKI N P GG E Q HIKEF G ISSN T EI N - G G Y Q YIEMN GTA EYSVL N D G - Y Q I 102
Cdd:NF033176 47 A F A QNISS G VVSG GVV SSGET Q V VY sn G QTS N ATV N S GG I Q NVNNG G KTTS T TV N s S G A Q NVGNS GTA ISTIV N S G g V Q R 126
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 103 V QM GG AANQ T T L NN G VLQV Y G --- A A N EPTIK GG RLI I EKD GI TVFAA I EK GG LLE V KE GG L A FAVDQKAG G A -- I KTTT 177
Cdd:NF033176 127 V SS GG VTSA T S L SG G AQNI Y N lgh A S N TVIFN GG NQT I FSG GI SDDTN I SS GG QQR V SS GG V A SNTTINSS G T qn I LSGG 206
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 178 RAMEVFGTNRLG Q FDIKD G I A NNMLLEN GG SL RV EENDF A YN T TV d SGG LLE V MD GG T A TGVDKKAG G KLI V STN A LEVS 257
Cdd:NF033176 207 STVSTHISSGGN Q YISAG G N A SATVVSS GG FQ RV SSGGT A TG T VL - SGG TQN V SS GG S A ISTSVYSS G VQT V YAG A TVTD 285
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 258 G T - NS K G QFS I KD G VSKNYELDDG SG L -------- IVMEDTQAIDTILDEHATMQS L GK D T G TR - VQANA V YDLGRSD Q N 327
Cdd:NF033176 286 T T v NS G G KQN I SS G GIVSGTIVNS SG T qniysggs ALSANIKGSQIVNSDGTAINT L VN D G G YQ h IRNGG V ASGTIIN Q S 365
330 340 350 360
....*....|....*....|....*....|....*....|..
gi 446476363 328 G SITY SS KAIS E NMV IN N G RAN ------ VWA GT MV N V S V R G N 363
Cdd:NF033176 366 G RVNI SS GGYA E STI IN S G GTQ svlsgg YAS GT LI N N S G R E N 407
auto_AIDA-I
NF033176 autotransporter adhesin AIDA-I;
52-402
5.58e-14
autotransporter adhesin AIDA-I;
Pssm-ID: 380183 [Multi-domain]
Cd Length: 1287
Bit Score: 76.62
E-value: 5.58e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 52 G TANN T K I NP GG E Q H I KEF G IS S N T EIN - GG Y Q YIEMN GTA EYS VL ND G Y Q I V QM GG A A NQ T TL - NN GV LQ VY GA A NEPT 129
Cdd:NF033176 206 G STVS T H I SS GG N Q Y I SAG G NA S A T VVS s GG F Q RVSSG GTA TGT VL SG G T Q N V SS GG S A IS T SV y SS GV QT VY AG A TVTD 285
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 130 I --- K GG RLI I EKD GI TVFAAIEKG G LLEVKE GG L A FAVDQ K AGGAIKTTTR A MEVFGTNRLG Q FDIKD G I A NNMLLENG 206
Cdd:NF033176 286 T tvn S GG KQN I SSG GI VSGTIVNSS G TQNIYS GG S A LSANI K GSQIVNSDGT A INTLVNDGGY Q HIRNG G V A SGTIINQS 365
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 207 G SLRVEENDF A YN T TVD SGG LLE V MD GG T A T G VDKKAG G KLI VS TNALEVSGTNSK G -- Q FSIKD G VSKNYELDDGSGLI 284
Cdd:NF033176 366 G RVNISSGGY A ES T IIN SGG TQS V LS GG Y A S G TLINNS G REN VS NGGSAYNTIINA G gn Q YIYSN G EASGTTVNTSGFQR 445
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 285 V MEDTQ A ID T I L DEHATMQ S lgkd T G TRVQ A NA VY DL G R sdqng SIT Y SSKAI S ENMVINN G RA NV WA G TMVNV SV R gnd 364
Cdd:NF033176 446 V NSGGT A TG T K L SGGNQNV S ---- S G GKAI A AE VY SG G K ----- QTV Y AGGEA S GTQIFDG G VV NV SG G SVSGA SV N --- 513
330 340 350
....*....|....*....|....*....|....*...
gi 446476363 365 gilev MKPQI N YAPAMLV G KVVVS EG ASLRTH GA VD TS 402
Cdd:NF033176 514 ----- LNGRL N VFAGNVT G TILNQ EG RQYIYS GA SA TS 546
YhjY
COG5571 Uncharacterized conserved protein YhjY, contains autotransporter beta-barrel domain [General ...
372-863
1.26e-11
Uncharacterized conserved protein YhjY, contains autotransporter beta-barrel domain [General function prediction only];
Pssm-ID: 444313 [Multi-domain]
Cd Length: 648
Bit Score: 68.37
E-value: 1.26e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 372 PQINY A PAMLVGKVVVSEG A SLRTHG A VDTSK A DV --- SLENS A WTII A DITTTNQNTP L NLANL A MS GA NVIMM -- A EP 446
Cdd:COG5571 162 GVAGT A ALNGATANTGLGA A AALAAA A AAAAA A AA aaa AAAAA A TAAA A AAAAAAAAAV L ASPAP A AG GA AAAAA ga A AA 241
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 447 VTRSSVT A SAENFTT L TTNT L SG NGN FYMRTDMANHQSD ql NVT G QAT GD FKIFVTDTGASPA A GDSLTLV T TGGGDAAF 526
Cdd:COG5571 242 AASAAAN A ATQANLL L LALA L GS NGN AVGLNAVGLANEA -- AAP G AVG GD AGSTGATPSTLSS A SCVASSL T AANANTLY 319
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 527 TLGNAG G VVDIGTY eytlldngnhsw SL A ENR A QITPSTTDVLNMA A AQPLVFD A ELDT V RERL G SVKGVSYDTAMWS sa 606
Cdd:COG5571 320 AAADTA G PAGATAA ------------ LA A AAA A VLASAAAVAQAAL A LAAAGGQ A RSLA V AAGQ G RGARGGQTRGGGG -- 385
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 607 i NTRNNVTTDAGA G FEQTLTG LTLG I D S R F S R ees STIR G LFFG Y SHS D IG F DR GG KGNVD S YT L GA YAG W e HQN G AY VD 686
Cdd:COG5571 386 - AGGTTGGGVGAG G GDGDGPN LTLG V D Y R L S D --- NLLL G AALS Y GRQ D LD F GD GG SYDAR S TS L SL YAG Y - RAG G LW VD 460
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 687 GVVKVDRFANT I HGKMSN G A --- T AF GD YSSNGA GA HVES G FRWVD G LWSVR P YLAFT ------- G F T TD G QD ytl S NGM 756
Cdd:COG5571 461 ADLSYGDLDYD I RRHIRL G P atr T ET GD TDGSQW GA RLTA G YDFTA G RLRTG P FAGLD yqkvkvd G Y T ET G AG --- S TAL 537
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 757 RADVGNTRI L RAEA G TAVS Y HM dlqn GTTLE P WLKA A VRQ E YA D SN ----- QVKVNDD G K F --- NNDVAGTR G VYQA G IR 828
Cdd:COG5571 538 SFGDQDRDS L VGSL G WRAD Y QL ---- LGRFN P YAEV A YEH E FG D DD rdvta GLASLPA G S F slp AAAPDKNW G RATL G AS 613
490 500 510
....*....|....*....|....*....|....*
gi 446476363 829 SSF T PTL S GHLSV S YGN G AGVESPWNTQA G VVWT F 863
Cdd:COG5571 614 AAL T NGV S LFAGY S GTF G RDDGRQTSVNL G LSAR F 648
auto_AIDA-I
NF033176 autotransporter adhesin AIDA-I;
52-296
1.47e-08
autotransporter adhesin AIDA-I;
Pssm-ID: 380183 [Multi-domain]
Cd Length: 1287
Bit Score: 58.90
E-value: 1.47e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 52 G T A NN T K IN PG G EQHIKEF G ISS NT E IN - GG Y QYI EM NG T A EYSVL N - D G Y Q I V QM GG A A NQ T T L NN G vlqvygaa N EPT 129
Cdd:NF033176 393 G Y A SG T L IN NS G RENVSNG G SAY NT I IN a GG N QYI YS NG E A SGTTV N t S G F Q R V NS GG T A TG T K L SG G -------- N QNV 464
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 130 IK GG RL I I ekdgitvf A AIEK GG LLE V KE GG L A FAVDQKA GG AIKTTTRAMEVFGT N RL G QFDIKD G IANNML L ENG G SL 209
Cdd:NF033176 465 SS GG KA I A -------- A EVYS GG KQT V YA GG E A SGTQIFD GG VVNVSGGSVSGASV N LN G RLNVFA G NVTGTI L NQE G RQ 536
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 210 RVEENDF A YN T TVDSG G LLE V MD GG T A T G VDKKA GG KLI VS TNALEVSGTNSK G -- QF SIKD G VSKNYELDD G SGLI V ME 287
Cdd:NF033176 537 YIYSGAS A TS T VANNE G REY V LS GG V A D G TVLNS GG LQA VS SGGSASATVINE G gs QF VYEG G NVTGTVIKN G GAIR V DS 616
....*....
gi 446476363 288 DTQ A IDTI L 296
Cdd:NF033176 617 GAS A LNIA L 625
PRK14849
PRK14849 autotransporter barrel domain-containing lipoprotein;
481-759
1.32e-05
autotransporter barrel domain-containing lipoprotein;
Pssm-ID: 184851 [Multi-domain]
Cd Length: 1806
Bit Score: 49.35
E-value: 1.32e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 481 N HQS D QL NV T G QAT G DFKIF V TDT G ASP A AGDSLTLVTTG GG DA A FTLGNAG G V V DI G T Y E YTL LD --- N GNHS W S L AEN 557
Cdd:PRK14849 1375 N SPT D KM NV K G DTQ G NTRVR V DNI G GVG A QTVNGIELIEV GG NS A GNFALTT G T V EA G A Y V YTL AK gkg N DEKN W Y L TSK 1454
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 558 RAQI TP - S T T D VL N maaa Q P L V F D A E LDT V - R ERL GS - VKGVSYDTAMW S SAINT R ------- NNVTTDAG A -------- 619
Cdd:PRK14849 1455 WDGV TP p D T P D PI N ---- N P P V V D P E GPS V y R PEA GS y ISNIAAANSLF S HRLHD R lgepqyi DSLHSQGS A ssmwmrhv 1530
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 620 - G F E QTLT G ------------ L T LG I D -- SRF S REESSTIR G LFF GY S -- HS DIGFD R G G --- K G NVDS Y TL G A YA G W -- 677
Cdd:PRK14849 1531 g G H E RSRA G dgqlntqanryv L Q LG G D la QWS S NAQDRWHL G VMA GY A nq HS NTQSN R V G yks D G RISG Y SA G L YA T W yq 1610
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 678 -- EHQN GAYVD GVVKVDR F A N TI hgkm S NGATAFG DY S S N G AG A H VE S G FRWVD G ---------- L W S V R P YLAF T GFTT 745
Cdd:PRK14849 1611 nd ANKT GAYVD SWALYNW F D N SV ---- S SDNRSAD DY D S R G VT A S VE G G YTFEA G tfsgsegtln T W Y V Q P QAQI T WMGV 1686
330
....*....|....
gi 446476363 746 DGQ D Y T LSN G M R AD 759
Cdd:PRK14849 1687 KDS D H T RKD G T R IE 1700
Name
Accession
Description
Interval
E-value
autotrans_barl
TIGR01414 outer membrane autotransporter barrel domain; A number of Gram-negative bacterial proteins, ...
468-863
1.21e-104
outer membrane autotransporter barrel domain; A number of Gram-negative bacterial proteins, mostly found in pathogens and associated with virulence, contain a conserved C-terminal domain that integrates into the outer membrane and enables the N-terminal region to be delivered across the membrane. This C-terminal autotransporter domain is about 400 amino acids in length and includes the aromatic amino acid-rich OMP signal, typically ending with a Phe or Trp residue, at the extreme C-terminus. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis]
Pssm-ID: 273608 [Multi-domain]
Cd Length: 431
Bit Score: 330.11
E-value: 1.21e-104
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 468 S GNG N F Y M R TD MA -- N H Q S D Q L N V T G Q A T G DFKIF V TDT G ASP A A - GD SL TLVT T - GG G DAAFTL G N ag G V VD I G T Y E YT 543
Cdd:TIGR01414 15 T GNG G F V M N TD LG gd N S Q T D R L V V N G N A S G TTGVV V NNI G GEG A Q t GD GI TLVT V n GG S DAAFTL A N -- G K VD A G A Y T YT 92
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 544 L LD NG --- N HS W S L AENRAQI TP STTDV --------- LNM A A A QPLV F D AELDT V R E R L G SVKGVSY D TA -- M W SSAINT 609
Cdd:TIGR01414 93 L YK NG ted N NN W Y L TSSLPDL TP PGQQL sptyraeag SYA A N A NAAL F L AELDT L R Q R M G DLRSAAR D AG ng V W ARIFGG 172
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 610 R N NVTT DAG - AG FE Q TL TG LT LG I D SRFSR - EESSTIR GL FF GY SHS DI GFD --- R GGKG N VD S Y T LG A Y AG W EHQN GAY 684
Cdd:TIGR01414 173 D N HLDG DAG a AG YD Q NT TG VQ LG G D ILLAG n ADGDLHV GL MA GY AKA DI KTR syk Y GGKG K VD G Y G LG L Y GT W LQDS GAY 252
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 685 VDGV VKVD RF A N TIHGKM SNG a TAF G D Y S SNG AG A HV E S G F R W -- VDGL W S V R P YLAFTG F TTD G Q DY TL SNG M R ADV G N 762
Cdd:TIGR01414 253 VDGV LQYS RF R N DVSSTG SNG - KVS G K Y N SNG FT A SL E A G Y R Y nl GGNG W Y V E P QAQLSY F GVS G D DY KE SNG T R VLG G G 331
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 763 TRI L RAEA G TA V S Y HM DL QN G TTLE P W LKA A V RQ E YADSNQ V K VN DD g KFN ND VA GTR GV Y QA G IRSSFTPT LS GHLS V S 842
Cdd:TIGR01414 332 GDS L QGRL G LR V G Y QF DL GT G RAVK P Y LKA N V LH E FKGGTG V R VN GV - TIR ND FS GTR AE Y GV G VNAKIKDN LS LYAD V D 410
410 420
....*....|....*....|.
gi 446476363 843 Y GN G AGVESPWNTQA GV VWT F 863
Cdd:TIGR01414 411 Y QK G GKKYTDNQGNL GV RYS F 431
AidA
COG3468 Autotransporter adhesin AidA [Cell wall/membrane/envelope biogenesis, Intracellular ...
71-863
1.92e-48
Autotransporter adhesin AidA [Cell wall/membrane/envelope biogenesis, Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 442691 [Multi-domain]
Cd Length: 846
Bit Score: 185.15
E-value: 1.92e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 71 G ISSNTEIN GG YQYIEMNGTAEY S VLND G YQIVQM GG AANQTTLNN G VLQVYGAANEPTIK GG RLIIEKD G ITVFAAIEK 150
Cdd:COG3468 58 G GGGGAGGG GG GAGSGGGLAGAG S GGTG G NSTGGG GG NSGTGGTGG G GGGGGSGNGGGGGG GG GGGGTGG G GGGGTGSAG 137
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 151 GG LLEVKE G GLAFAVDQK A G G AIKTTTRAMEVF G TNRL G QFDIKD G IANNMLLENG G SLRVEENDFAYNTTVDS GG L le V 230
Cdd:COG3468 138 GG GGGGGG G TGVGGTGAA A A G GGTGSGGGGSGG G GGAG G GGGGGA G GSGGAGSTGS G AGGGGGGSGGGGGAAGT GG G -- G 215
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 231 MD GG T A T G VDKK AG GKLIVSTNALEVS G TNSKGQFSIKD G VSKNYELDD G S G LIVMEDTQAIDTILDEHATMQSLGKD TG 310
Cdd:COG3468 216 GG GG G A G G ATGG AG SGGNTGGGVGGGG G SAGGTGGGGLT G GGAAGTGGG G G G TGTGSGGGGGGGANGGGSGGGGGASG TG 295
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 311 TRVQ A NAVYDL G RSDQ NG SITYSSKAISENMVINN G RANVWA G TMVNVSVR G ND G IL evmkpqinyapaml V G KVVVSE G 390
Cdd:COG3468 296 GGGT A STGGGG G GGGG NG GGGGGGSNAGGGSGGGG G GGGGGG G GGTTLNGA G SA G GG -------------- T G AALAGT G 361
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 391 A S LRTH G AVDT S KADVSLENSAWTIIA D ITT T NQN T PLNLA N LAMSGANVIMMAEPV T RSSV T ASAENF ttlttntl SG N 470
Cdd:COG3468 362 G S GSGG G GGGG S GGGGGAGGGGANTGS D GVG T GLT T GGTGN N GGGGVGGGGGGGLTL T GGTL T VNGNYT -------- GN N 433
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 471 G NFYMR T DMANHQ S -- D Q L N V T G QAT G DFKIF V TDT G ASP A A - GDSLTL V TTG G G - D A AFTLG NA ggv V DI G T YEYTL -- 544
Cdd:COG3468 434 G TLVLN T VLGDDN S pt D R L V V N G NTS G TTGVR V NNA G GLG A Q t VNGIEV V EVN G A s D G AFTLG GR --- V VA G A YEYTL yq 510
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 545 -- LDNGNHS W S L ------- AENRAQIT P STTDV L NMA AA qp LVFDA EL D T VRE RLG ---- SVK G V S YDTAM W SSAINTR N 611
Cdd:COG3468 511 gg SGGDDGN W Y L rstltpp DPPTPVYR P EVPSY L ANP AA -- ANGLF EL G T LHD RLG erry TDT G E S DNSGA W LRVEGGH N 588
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 612 NVTTDA G - AGFEQTLT GL T LG I D SRFSREESSTIR - G LFF GY SHS D I ---- GFDRG GKG N VD S Y T LG A Y AG W EHQ NG A YV 685
Cdd:COG3468 589 RSRDSS G q LDYDSNRY GL Q LG G D LLQWEDGGGRLH v G VMA GY GNG D S dvrs RATGT GKG D VD G Y S LG L Y GT W YGN NG F YV 668
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 686 DGV VKVDR F A N TIHGKMSN G A T af G D Y SS NG AG A HV E S G FRW - VDGL WS VR P YLAFTGFTT D GQ D Y T L SNG M R ADVGNTR 764
Cdd:COG3468 669 DGV LQYSW F D N DVSSDDLG G V T -- G S Y DG NG YS A SL E A G YPF k LGEG WS LE P QAQLIYQGV D FD D F T D SNG T R VSGDDGD 746
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 765 I L RAEA G TAVS Y HMDLQN G TT L E P W L K A AVRQ E YADS N Q V K VN DD g K F NN D VA GT R G VYQA G IRSSFTPT LS GHLS V S Y - 843
Cdd:COG3468 747 S L QGRL G LRLG Y EFHWDD G RA L Q P Y L E A NWLH E FLGD N S V T VN GV - S F SQ D GS GT W G ELGL G VTGQLNKN LS LYGD V G Y q 825
810 820
....*....|....*....|.
gi 446476363 844 - G NGAGVE S PWNTQA GV VWT F 863
Cdd:COG3468 826 t G LDGYDS S DTSGNL GV RYS F 846
auto_BafA_Cterm
NF040482 BafA family autotransporter C-terminal domain; BafA from both Bartonella henselae and ...
306-846
2.38e-47
BafA family autotransporter C-terminal domain; BafA from both Bartonella henselae and Bartonella quintana, and possibly all Bartonella BafA, are mitogenic autotransporter virulence factors that help induce vasoproliferative lesions during infection. This HMM represents the more conserved C-terminal portion only, as the passenger region is more highly variable in length and sequence.
Pssm-ID: 468508 [Multi-domain]
Cd Length: 617
Bit Score: 179.07
E-value: 2.38e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 306 G KDTG T R V QANA V YDLGRSD Q N gsi TYSSKAISENM V INN G RAN V W AG TMV n VS V RG N DGILEVMKP ------- Q IN --- 375
Cdd:NF040482 30 G IAWN T K V MQGG V QNVAKKS Q S --- AKNGGFAFNTE V FGG G KQR V L AG GKA - IG V TL N ETAVQEIYA ggfvknl T IN dea 105
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 376 ---- YA P A M L V GK VV V SEGAS L RTHGAV D --- T SKA D VS L -- ENSAWTI I A D ITTTNQNTPLN L anlam SG ANVIMM A ep 446
Cdd:NF040482 106 kswv YA G A T L E GK TL V NHSGQ L YLYAGD D khh T TVE D II L ng RDTKLYS I V D EFDGKSSLIQK L ----- SG EGSVIF A -- 178
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 447 vtrss V T A S AENFTT L TT N T LSG NGN F YMR T DM A NHQS D Q L NV t GQAT G DFK I F V T D T G A -- SPAAGDSLT L V T TGG G D A 524
Cdd:NF040482 179 ----- S T G S DPYYSQ L HV N N LSG SLH F KFN T SI A GNRG D Y L FI - ENGK G NHT I S V A D S G V ei TDPFSNKRD L I T DQS G G A 252
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 525 A FTL G N AG G ---- V VD I GTY E Y T L --- L D NGNHS W S L AEN R AQ ------------------- I TPST TD VL N MA A A QP L V 578
Cdd:NF040482 253 N FTL T N LS G ekin A VD G GTY M Y G L kqr K D ENGKI W Y L SAD R IS gqessspdpseplsvsdfl T TPST DA VL S MA V A PG L I 332
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 579 F DA EL D TVR ERL G SVKGVSYD TA M W SS AI NTRNNVT T DA g AG F EQTL TG LT LG I D SRFSREESSTIR G L F FG Y SHSD I GF 658
Cdd:NF040482 333 F NN EL Q TVR TGR G ILDRNKKN TA L W TY AI KSKERIA T GH - TH F KLEQ TG IV LG A D GLSELTHGDLYI G G F GS Y DQAR I AH 411
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 659 D RGG KGNVDS Y TL GAYA GWEHQN G A Y V DG VV K VDRFA N TIHGKMS NG ATAF GDY SSNGA G AHV E S G F R WVDGLWS - VR PY 737
Cdd:NF040482 412 A RGG VSDINT Y SI GAYA TYFDHR G W Y L DG IL K YNYYQ N NLKAVST NG LAIQ GDY NQWAI G TSF E A G Y R FETAQNT w MQ PY 491
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 738 LAF T GFTTD G QDYT LSNGM RA D VGNTRI LR A E A G TAVSYHMDLQNG T T L EPWLK AA VRQ E YA D S N QVKV N DDG KF NN D VA 817
Cdd:NF040482 492 GQL T WLQVE G KKIK LSNGM TG D ISPSTS LR S E V G LSAGHEFIVGAE T S L TAYIT AA WLR E NI D N N HTTI N KQH KF IT D LS 571
570 580
....*....|....*....|....*....
gi 446476363 818 G TR G VYQA G IR S SFTPT L SGHLSVS Y GN G 846
Cdd:NF040482 572 G NA G KLGI G LN S FVSDK L TLYAEAH Y LK G 600
Pertactin
pfam03212 Pertactin;
430-556
2.39e-39
Pertactin;
Pssm-ID: 460848 [Multi-domain]
Cd Length: 121
Bit Score: 141.76
E-value: 2.39e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 430 L A N LA M SG AN V IM maepvtr S S VTAS A EN F T TLTT N TLSG N G N F Y M RT D M A NHQS DQL N V T G Q A T G DFKIF V TD TG AS PA 509
Cdd:pfam03212 1 V A A LA L SG GT V DF ------- A S PAEP A GA F K TLTT Q TLSG S G T F V M NA D V A SGTG DQL V V S G N A S G QHVLL V RN TG SE PA 73
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 446476363 510 A G DS - LTLV T TGGGDAAFTLGN A GG V VD I GTY E Y T L LDN GN HS WSL AE 556
Cdd:pfam03212 74 S G NT k LTLV E TGGGDAAFTLGN K GG K VD A GTY R Y R L TAD GN GN WSL TA 121
PL1_Passenger_AT
cd01343 Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 1, of ...
302-561
4.62e-38
Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 1, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of Neisseria and Haemophilus IgA1 proteases, SPATEs (serine protease autotransporters secreted by Enterobacteriaceae), Bordetella pertacins, and nonprotease autotransporters, TibA and similar AIDA-like proteins.
Pssm-ID: 238653 [Multi-domain]
Cd Length: 233
Bit Score: 142.11
E-value: 4.62e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 302 MQSLGKDTGTRVQA NA VYD LG RS - DQNG S I T YSSK A -- ISE N MVINNGRAN vwa G T MVNVSV RG N dgi LEVMKP Q INY A P 378
Cdd:cd01343 1 GRLVSDGGNITAGD NA QLT LG GG a LYGS S V T LTNG A vl DAG N ANLSAAASY --- A T LSGSNI RG T --- VVLGAG Q PLQ A L 74
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 379 A mlvg KVVVSEG A SL rt H GA VDTSK A D VSL E - NS A WT IIA D I tttnqntpl N LA NL AMS G AN V IMMAEPVTR - SSV T A sa 456
Cdd:cd01343 75 A ---- ELLLGGN A AW -- T GA IQGLN A T VSL N l NS V WT LTG D S --------- N VN NL TLN G GT V DFNGPSAGK f NTL T V -- 137
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 457 enfttltt NTLSGNG N F Y MRTD M A NH Q S D Q L N VTG Q ATGDF KIF V TD TG AS P AA G DS LTLV T T G - GGDA A FTL G N ag G V V 535
Cdd:cd01343 138 -------- NTLSGNG T F V MRTD L A GG Q G D K L V VTG S ATGDF NLL V VN TG KE P TS G LN LTLV S T P k GGDA E FTL A N -- G T V 207
250 260
....*....|....*....|....*.
gi 446476363 536 D I G T Y E YTL LDN GN HS W S L AENRAQI 561
Cdd:cd01343 208 D L G A Y R YTL VKD GN GN W T L TGPKKES 233
Autotransporter
pfam03797 Autotransporter beta-domain; Secretion of protein products occurs by a number of different ...
602-842
4.17e-35
Autotransporter beta-domain; Secretion of protein products occurs by a number of different pathways in bacteria. One of these pathways known as the type V pathway was first described for the IgA1 protease. The protein component that mediates secretion through the outer membrane is contained within the secreted protein itself, hence the proteins secreted in this way are called autotransporters. This family corresponds to the presumed integral membrane beta-barrel domain that transports the protein. This domain is found at the C terminus of the proteins it occurs in. The N terminus contains the variable passenger domain that is translocated across the membrane. Once the passenger domain is exported it is cleaved auto-catalytically in some proteins, in others a different protease is used and in some cases no cleavage occurs.
Pssm-ID: 461054 [Multi-domain]
Cd Length: 255
Bit Score: 134.43
E-value: 4.17e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 602 M W SSAINT R NNV - TTDAG AG FEQTLT GL TL G I D S R FS ree SSTIR G LF FGYS H SD IGF D - RGG K G NV DSY T LG A Y AGWEH 679
Cdd:pfam03797 1 V W ARGFGG R GKQ d GDGGA AG YDADTG GL QV G A D Y R LG --- DNLRL G VA FGYS R SD ADV D g RGG S G DS DSY S LG L Y GTYYG 77
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 680 QN G A Y V DG VVKVDRFA N TIHGKMSN G A --- TA F GDY SS NG A GA HV E S G F R W - VD G L W SVR P YLAFTGFTTDGQDY T L S N G 755
Cdd:pfam03797 78 DG G W Y L DG GLGYGWHD N DTRRSVDL G G fse TA K GDY DG NG F GA SL E A G Y R F a LG G G W TLE P FAGLAYVRLRLDGF T E S G G 157
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 756 --- MRA D VGNTRI L RAEA G TAV SY HM DL QN G t TL E P WLKAAV R Q E YA D SNQ V KVNDDGK --------- FNN D V A GTRGVY 823
Cdd:pfam03797 158 aaa LSV D SQSYDS L TGRL G LRL SY TF DL GG G - TL T P YARLGW R H E FG D DDP V TTAAFAG lsgagsftv AGA D L A RDSLEL 236
250
....*....|....*....
gi 446476363 824 Q AG IRSSFTPT LS GHLSVS 842
Cdd:pfam03797 237 G AG LSAQLSDN LS LYANYD 255
Autotransporter
smart00869 Autotransporter beta-domain; Secretion of protein products occurs by a number of different ...
608-846
2.45e-30
Autotransporter beta-domain; Secretion of protein products occurs by a number of different pathways in bacteria. One of these pathways known as the type IV pathway was first described for the IgA1 protease. The protein component that mediates secretion through the outer membrane is contained within the secreted protein itself, hence the proteins secreted in this way are called autotransporters. This family corresponds to the presumed integral membrane beta-barrel domain that transports the protein. This domain is found at the C-terminus of the proteins it occurs in. The N-terminus contains the variable passenger domain that is translocated across the membrane. Once the passenger domain is exported it is cleaved auto-catalytically in some proteins, in others a different peptidase is used and in some cases no cleavage occurs.
Pssm-ID: 214872 [Multi-domain]
Cd Length: 268
Bit Score: 120.75
E-value: 2.45e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 608 NTRNNVTTDAG AGF EQTLT GL T LG I D S R F S r EESSTIR G LFF GY SH S DIG F D --- RG GKG N VDSY T LG A YAG WEHQ NG A Y 684
Cdd:smart00869 8 LRQDSSGSGGS AGF DYDSY GL Q LG A D Y R L S - DNGNLSL G FAA GY GN S KVD F S gnk GS GKG D VDSY G LG L YAG YSLG NG L Y 86
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 685 V D GVVKVD R FA N TIHG K MSN G -- AT A F G D Y SSN G A GA HV E S G F R W - VD G LWSVR P YLAFTGFTTDGQDY T L S N G ---- MR 757
Cdd:smart00869 87 L D AQLGYG R SD N DTKR K VTL G ga GR A K G S Y DGT G Y GA SL E A G Y R F y LG G GLTLT P FAGLAYSRVRQDGF T E S G G gafg LS 166
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 758 A D VGNTRI L RAEA G TAVS Y HMD L QN G T TL E P W L KA A VRQEYA D S N Q V KVN ------- DDGKFNN D VAGTRGVYQA G IRSS 830
Cdd:smart00869 167 V D SQSLDS L SLPL G LRLE Y RLA L GD G A TL T P Y L RL A YVHDFY D D N P V VTA sllgsga SFTTSGT D LDRNAAELGL G LSAK 246
250
....*....|....*.
gi 446476363 831 FTPT LS GH L SVSYGN G 846
Cdd:smart00869 247 LSNG LS LS L NYDGEF G 262
PRK09945
PRK09945 hypothetical protein; Provisional
89-503
2.42e-23
hypothetical protein; Provisional
Pssm-ID: 137602 [Multi-domain]
Cd Length: 418
Bit Score: 103.64
E-value: 2.42e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 89 G TAEYSVLN DG - Y QIV QM G GAANQ T T L NN G -- VLQVY G A A NEPTIK G - G R L IIEKD GI TVFAAIEKG G L L E V KE G GL A FA 164
Cdd:PRK09945 2 G SDAKNLMS DG n V QIV KT G EVIGA T Q L TE G el IVEAG G R A ENTVVT G a G W L KVATG GI AKCTQYGNN G T L S V SD G AI A TD 81
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 165 VD Q KA GGAI KTT T R A M e V F G TNRL G Q F DIKD G I A NNM LLENGG S LRV E E NDF A YNTTV D SG G L L E V md G GT ATG V DKKA G 244
Cdd:PRK09945 82 IV Q SE GGAI SLS T L A T - V N G RHPE G E F SVDQ G Y A CGL LLENGG N LRV L E GHR A EKIIL D QE G G L L V -- N GT TSA V VVDE G 158
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 245 G K L I V STN alevsgtnskgqfsikd G VSK N Y E LDD G S gl IV M EDTQ A I DT I L DE h A TM QS L - G K D TG T R V QANAV Y D LG r 323
Cdd:PRK09945 159 G E L L V YPG ----------------- G EAS N C E INQ G G -- VF M LAGK A S DT L L AG - G TM NN L g G E D SD T I V ENGSI Y R LG - 217
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 324 sd QN G SIT YSS KA i SE N MVI N - N GRA N V W AGT MV N VSVR G NDG IL ------- E VMKPQINY AP AM L V G K V VVSE GAS LRT 395
Cdd:PRK09945 218 -- TD G LQL YSS GK - TQ N LSV N v G GRA E V H AGT LE N AVIQ G GTV IL lsptsad E NFVVEEDR AP VE L T G S V ALLD GAS MII 294
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 396 HGAV D TSKADVSLENSAWT I IADI T TTNQNTPLNLA N LAMS G ANVIMMAEPV T RSSVTAS aenfttlttn T L S G N G NFYM 475
Cdd:PRK09945 295 GYGA D LQQSTITVQQGGVL I LDGS T VKGDSVTFSVG N INLN G GKLWLITGAA T HVQLKVK ---------- R L R G E G AICL 364
410 420
....*....|....*....|....*...
gi 446476363 476 R T DMANHQS D QL NV T G QA TGD FKIFV TD 503
Cdd:PRK09945 365 Q T SAKEISP D FI NV K G EV TGD IHVEI TD 392
PL_Passenger_AT
cd00253 Pertactin-like passenger domains (virulence factors) of autotransporter proteins of the type V ...
395-554
3.66e-19
Pertactin-like passenger domains (virulence factors) of autotransporter proteins of the type V secretion system. Autotransporters are proteins used by Gram-negative bacteria to transport proteins across their outer membranes. The C-terminal (beta) domain of autotransporters forms a pore in the outer membrane through which the N-terminal passenger domain is transported. Following transport, the passenger domain is generally cleaved by an outer membrane protease with the passenger domain either remaining in contact with the surface via a noncovalent interaction with the beta domain or cleaved to release a soluble protein. These proteins are highly diverse and perform a variety of functions that promote virulence, including catalyzing proteolysis, serving as an adhesin, mediating actin-promoted motility, or serving as a cytotoxin. Proteins in this family share similarity in the C-terminal region of the passenger domain as seen in the pertactin structure P.69, a Bordetella pertussis agglutinogen responsible for human pertussis. The P.69 protein consists of a 16-stranded parallel beta-helix with a V-shaped cross-section, and is one of the largest beta-helix known to date.
Pssm-ID: 238156 [Multi-domain]
Cd Length: 186
Bit Score: 86.27
E-value: 3.66e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 395 TH G AVDTSKAD VSL ENSAWTIIADIT T T N qntplnl A NL AM SG AN V IMMAEPVTRSSV T A saenfttl TT N T L S GNG N F Y 474
Cdd:cd00253 31 WL G TLQAGGGT VSL NSNSLWTLTGDS T V N ------- G NL TN SG GT V DFGSASGAFNTL T V -------- NG N Y L G GNG T F V 95
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 475 MR TD MA -- N HQS D Q L N VTG Q A T G DFKIF V TDT G ASP A - A GD SLT LV TT - GG G DAAF T L GNA ggv VD I G T YEYTL LDN G -- 548
Cdd:cd00253 96 LN TD LG gd N SPT D K L V VTG N A S G TTNVA V VNA G GEG A s T GD GIE LV EV n GG S DAAF S L AGR --- VD A G A YEYTL YKG G vg 172
....*..
gi 446476363 549 - N HS W S L 554
Cdd:cd00253 173 n N GN W Y L 179
AIDA
pfam16168 Adhesin of bacterial autotransporter system, probable stalk; The AIDA repeat is found on ...
189-245
3.81e-16
Adhesin of bacterial autotransporter system, probable stalk; The AIDA repeat is found on bacterial autotransporter proteins. As the repeat is short and occurs multiple times, it is likely to be the region of the transporter that acts as the stalk between the beta-barrel inserted into the membrane and the N-terminal head domain.
Pssm-ID: 406554 [Multi-domain]
Cd Length: 57
Bit Score: 73.14
E-value: 3.81e-16
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*..
gi 446476363 189 G Q F D I KD G I A N N M LLENGGSL R V EENDF A YN TTVD S GG L L E V MD GGTATG VDKKA GG 245
Cdd:pfam16168 1 G A F S I SG G V A D N V LLENGGSL T V VAGTS A TD TTVD K GG T L D V QS GGTATG TVVNN GG 57
auto_AIDA-I
NF033176 autotransporter adhesin AIDA-I;
52-239
5.79e-15
autotransporter adhesin AIDA-I;
Pssm-ID: 380183 [Multi-domain]
Cd Length: 1287
Bit Score: 79.70
E-value: 5.79e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 52 G TANNTKI N PG G EQHIKEFGISSNTEING G Y QYI EMNGT A EYS V L N - D G YQI V QM GG A A NQ T T LN N G V LQ VY --- G A A NE 127
Cdd:NF033176 505 G SVSGASV N LN G RLNVFAGNVTGTILNQE G R QYI YSGAS A TST V A N n E G REY V LS GG V A DG T V LN S G G LQ AV ssg G S A SA 584
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 128 PT I - K GG RLIIEKD G ITVFAA I EK GG LLE V KE G GL A FAVDQKA GG AIK T T T R A M e V F GTN RL G Q F DIKDGI A N N ML LENG 206
Cdd:NF033176 585 TV I n E GG SQFVYEG G NVTGTV I KN GG AIR V DS G AS A LNIALSS GG NLF T S T G A T - V T GTN HY G S F SVSQNH A S N VV LENG 663
170 180 190
....*....|....*....|....*....|...
gi 446476363 207 G S L R V EENDF A YN TTV D S G G L L EVMD GG TAT G V 239
Cdd:NF033176 664 G L L A V TSGST A TD TTV N S A G R L RIDE GG ALD G T 696
auto_AIDA-I
NF033176 autotransporter adhesin AIDA-I;
27-363
1.71e-14
autotransporter adhesin AIDA-I;
Pssm-ID: 380183 [Multi-domain]
Cd Length: 1287
Bit Score: 78.16
E-value: 1.71e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 27 A L A STVEY G ETVD GVV LEKDI Q L VY -- G TAN N TKI N P GG E Q HIKEF G ISSN T EI N - G G Y Q YIEMN GTA EYSVL N D G - Y Q I 102
Cdd:NF033176 47 A F A QNISS G VVSG GVV SSGET Q V VY sn G QTS N ATV N S GG I Q NVNNG G KTTS T TV N s S G A Q NVGNS GTA ISTIV N S G g V Q R 126
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 103 V QM GG AANQ T T L NN G VLQV Y G --- A A N EPTIK GG RLI I EKD GI TVFAA I EK GG LLE V KE GG L A FAVDQKAG G A -- I KTTT 177
Cdd:NF033176 127 V SS GG VTSA T S L SG G AQNI Y N lgh A S N TVIFN GG NQT I FSG GI SDDTN I SS GG QQR V SS GG V A SNTTINSS G T qn I LSGG 206
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 178 RAMEVFGTNRLG Q FDIKD G I A NNMLLEN GG SL RV EENDF A YN T TV d SGG LLE V MD GG T A TGVDKKAG G KLI V STN A LEVS 257
Cdd:NF033176 207 STVSTHISSGGN Q YISAG G N A SATVVSS GG FQ RV SSGGT A TG T VL - SGG TQN V SS GG S A ISTSVYSS G VQT V YAG A TVTD 285
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 258 G T - NS K G QFS I KD G VSKNYELDDG SG L -------- IVMEDTQAIDTILDEHATMQS L GK D T G TR - VQANA V YDLGRSD Q N 327
Cdd:NF033176 286 T T v NS G G KQN I SS G GIVSGTIVNS SG T qniysggs ALSANIKGSQIVNSDGTAINT L VN D G G YQ h IRNGG V ASGTIIN Q S 365
330 340 350 360
....*....|....*....|....*....|....*....|..
gi 446476363 328 G SITY SS KAIS E NMV IN N G RAN ------ VWA GT MV N V S V R G N 363
Cdd:NF033176 366 G RVNI SS GGYA E STI IN S G GTQ svlsgg YAS GT LI N N S G R E N 407
COG4625
COG4625 Uncharacterized conserved protein, contains a C-terminal beta-barrel porin domain [Function ...
12-803
3.92e-14
Uncharacterized conserved protein, contains a C-terminal beta-barrel porin domain [Function unknown];
Pssm-ID: 443664 [Multi-domain]
Cd Length: 900
Bit Score: 76.74
E-value: 3.92e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 12 SAISVLVATALYSPIALASTVEY G ETVD G VVLEKDIQLVY G TANNTKINP GG EQHIKEF G ISSNTEIN GG YQYIEMN G T A 91
Cdd:COG4625 47 GGGAGGGGGGGGTGGGGGGGGGG G GGGA G GGGGGGGGGGG G GGTGGVGGG GG GGGGGGG G GGGGGGGG GG GSAGGGG G G A 126
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 92 EYSVLND G YQIVQM GG AANQTTLNN G VLQVY G A A NEPTIK GG rliiek D G ITVFAAIEK GG LLEVKE GG LAFAVDQKA GG 171
Cdd:COG4625 127 GGAGGGG G GGAGGG GG GGGGGGAGG G GGGGA G G A GGGGGG GG ------ G G GGGGGGGGG GG GGGGGG GG GGGNGGGGG GG 200
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 172 AIKTTTRAMEVF G TNRL G QFDIKD G IANNMLLEN GG SLRVEENDFAYNTTVDS GG LLEVMD GG TAT G VDKKA GG KLIVST 251
Cdd:COG4625 201 GGGGGGGGGGGG G AGGG G GGGGGG G GGGGGGGGG GG GGGGGGGGGGGAGGGGG GG GGNGGG GG AGG G GGGGG GG SGGGGG 280
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 252 NALEVSGTNSK G QFSIKD G VSKNYELDD G S G LIVMEDTQAIDTILDEHATMQSL G KDT G TRVQANAVYDL G RSDQN G SIT 331
Cdd:COG4625 281 GGGGGGSGGGG G GGGGGG G GGGGGGGGG G G G GGGGGGGGGGGGGGGGGGGGGGA G GGG G SGGAGAGGGGA G GGGAG G GGG 360
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 332 YSSKAISENMVINN G RANVWAGTMVNV S VR G ND G ILEVMKPQINYAPAMLV G KVVVSEG A SLRTH G AVDTSKADVSLENS 411
Cdd:COG4625 361 GGTGGGGGGGGGGG G GSGGGGAGGGGG S GG G GG G GAGGGGGGGGAGGTGGG G AGGGGGA A GGGGG G TGAGGGGGGGGTGA 440
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 412 AWTIIADITTTNQNTPLNLANL A MS G ANVIMM A EPV T RSSVTASAENF T TLTTNTLSGNGNFYMRTDMANHQ SD Q L N VTG 491
Cdd:COG4625 441 GGGGATGGGGGGGGGAGGSGGG A GA G GGSGSG A GTL T LTGNNTYTGTT T VNGGGNYTQSAGSTLAVEVDAAN SD R L V VTG 520
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 492 Q AT GDFKIF V TDT G ASPAAGDSLT L VTTGGG DA AFTL G NAGGVVD igty EYTL LD NGNHSWS L AENRAQ I TP S TTDV L NM 571
Cdd:COG4625 521 T AT LNGGTV V VLA G GYAPGTTYTI L AVAAAL DA LAGN G DLSALYN ---- ALAA LD AAAARAA L DQLSGE I HA S AAAA L LQ 596
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 572 A AAQPL - VFDAE L DTV R ERLGSVKGVSYDTAM W SSAINTRNNVTT D A G - AG FEQTLT GL TL G I D S R FS ree SSTIR G LFF 649
Cdd:COG4625 597 A SRALR d ALSNR L RAL R GAGAAGDAAAEGWGV W AQGFGSWGDQDG D G G a AG YDSSTG GL LV G A D Y R LG --- DNWRL G VAL 673
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 650 GYS H SD IGF D - RG GK G NV DSY T LG A Y A G WE h QNGA Y V DG VVKVDRFANTIHGKMSN G --- A TA FG DY SSNG A G A HV E S G F 725
Cdd:COG4625 674 GYS R SD VDV D d RG SS G DS DSY H LG L Y G G YQ - FGAL Y L DG GLGYGWNDYDTDRTIAF G gls R TA TA DY DGDT A S A FL E A G Y 752
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 726 R WVD G LWSVR P YLAFTGFTTDGQDY T LSN G --- MRA D VGN T RI LR AEA G TAV S YHMD L QN G T TL E P WLKAAV R Q E YA D SN 802
Cdd:COG4625 753 R FDL G GLTLT P FAGLAYVRLRTDGF T ETG G aaa LSV D SQS T DS LR STL G LRA S RTFS L GG G V TL T P SGRLGW R H E FG D DD 832
.
gi 446476363 803 Q 803
Cdd:COG4625 833 P 833
auto_AIDA-I
NF033176 autotransporter adhesin AIDA-I;
52-402
5.58e-14
autotransporter adhesin AIDA-I;
Pssm-ID: 380183 [Multi-domain]
Cd Length: 1287
Bit Score: 76.62
E-value: 5.58e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 52 G TANN T K I NP GG E Q H I KEF G IS S N T EIN - GG Y Q YIEMN GTA EYS VL ND G Y Q I V QM GG A A NQ T TL - NN GV LQ VY GA A NEPT 129
Cdd:NF033176 206 G STVS T H I SS GG N Q Y I SAG G NA S A T VVS s GG F Q RVSSG GTA TGT VL SG G T Q N V SS GG S A IS T SV y SS GV QT VY AG A TVTD 285
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 130 I --- K GG RLI I EKD GI TVFAAIEKG G LLEVKE GG L A FAVDQ K AGGAIKTTTR A MEVFGTNRLG Q FDIKD G I A NNMLLENG 206
Cdd:NF033176 286 T tvn S GG KQN I SSG GI VSGTIVNSS G TQNIYS GG S A LSANI K GSQIVNSDGT A INTLVNDGGY Q HIRNG G V A SGTIINQS 365
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 207 G SLRVEENDF A YN T TVD SGG LLE V MD GG T A T G VDKKAG G KLI VS TNALEVSGTNSK G -- Q FSIKD G VSKNYELDDGSGLI 284
Cdd:NF033176 366 G RVNISSGGY A ES T IIN SGG TQS V LS GG Y A S G TLINNS G REN VS NGGSAYNTIINA G gn Q YIYSN G EASGTTVNTSGFQR 445
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 285 V MEDTQ A ID T I L DEHATMQ S lgkd T G TRVQ A NA VY DL G R sdqng SIT Y SSKAI S ENMVINN G RA NV WA G TMVNV SV R gnd 364
Cdd:NF033176 446 V NSGGT A TG T K L SGGNQNV S ---- S G GKAI A AE VY SG G K ----- QTV Y AGGEA S GTQIFDG G VV NV SG G SVSGA SV N --- 513
330 340 350
....*....|....*....|....*....|....*...
gi 446476363 365 gilev MKPQI N YAPAMLV G KVVVS EG ASLRTH GA VD TS 402
Cdd:NF033176 514 ----- LNGRL N VFAGNVT G TILNQ EG RQYIYS GA SA TS 546
YhjY
COG5571 Uncharacterized conserved protein YhjY, contains autotransporter beta-barrel domain [General ...
372-863
1.26e-11
Uncharacterized conserved protein YhjY, contains autotransporter beta-barrel domain [General function prediction only];
Pssm-ID: 444313 [Multi-domain]
Cd Length: 648
Bit Score: 68.37
E-value: 1.26e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 372 PQINY A PAMLVGKVVVSEG A SLRTHG A VDTSK A DV --- SLENS A WTII A DITTTNQNTP L NLANL A MS GA NVIMM -- A EP 446
Cdd:COG5571 162 GVAGT A ALNGATANTGLGA A AALAAA A AAAAA A AA aaa AAAAA A TAAA A AAAAAAAAAV L ASPAP A AG GA AAAAA ga A AA 241
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 447 VTRSSVT A SAENFTT L TTNT L SG NGN FYMRTDMANHQSD ql NVT G QAT GD FKIFVTDTGASPA A GDSLTLV T TGGGDAAF 526
Cdd:COG5571 242 AASAAAN A ATQANLL L LALA L GS NGN AVGLNAVGLANEA -- AAP G AVG GD AGSTGATPSTLSS A SCVASSL T AANANTLY 319
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 527 TLGNAG G VVDIGTY eytlldngnhsw SL A ENR A QITPSTTDVLNMA A AQPLVFD A ELDT V RERL G SVKGVSYDTAMWS sa 606
Cdd:COG5571 320 AAADTA G PAGATAA ------------ LA A AAA A VLASAAAVAQAAL A LAAAGGQ A RSLA V AAGQ G RGARGGQTRGGGG -- 385
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 607 i NTRNNVTTDAGA G FEQTLTG LTLG I D S R F S R ees STIR G LFFG Y SHS D IG F DR GG KGNVD S YT L GA YAG W e HQN G AY VD 686
Cdd:COG5571 386 - AGGTTGGGVGAG G GDGDGPN LTLG V D Y R L S D --- NLLL G AALS Y GRQ D LD F GD GG SYDAR S TS L SL YAG Y - RAG G LW VD 460
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 687 GVVKVDRFANT I HGKMSN G A --- T AF GD YSSNGA GA HVES G FRWVD G LWSVR P YLAFT ------- G F T TD G QD ytl S NGM 756
Cdd:COG5571 461 ADLSYGDLDYD I RRHIRL G P atr T ET GD TDGSQW GA RLTA G YDFTA G RLRTG P FAGLD yqkvkvd G Y T ET G AG --- S TAL 537
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 757 RADVGNTRI L RAEA G TAVS Y HM dlqn GTTLE P WLKA A VRQ E YA D SN ----- QVKVNDD G K F --- NNDVAGTR G VYQA G IR 828
Cdd:COG5571 538 SFGDQDRDS L VGSL G WRAD Y QL ---- LGRFN P YAEV A YEH E FG D DD rdvta GLASLPA G S F slp AAAPDKNW G RATL G AS 613
490 500 510
....*....|....*....|....*....|....*
gi 446476363 829 SSF T PTL S GHLSV S YGN G AGVESPWNTQA G VVWT F 863
Cdd:COG5571 614 AAL T NGV S LFAGY S GTF G RDDGRQTSVNL G LSAR F 648
AIDA
pfam16168 Adhesin of bacterial autotransporter system, probable stalk; The AIDA repeat is found on ...
263-316
2.68e-11
Adhesin of bacterial autotransporter system, probable stalk; The AIDA repeat is found on bacterial autotransporter proteins. As the repeat is short and occurs multiple times, it is likely to be the region of the transporter that acts as the stalk between the beta-barrel inserted into the membrane and the N-terminal head domain.
Pssm-ID: 406554 [Multi-domain]
Cd Length: 57
Bit Score: 59.27
E-value: 2.68e-11
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 446476363 263 G Q FSI KD GV SK N YE L DD G SG L I V MED T Q A I DT IL D EHA T M -- QS L G KD TGT R V QAN 316
Cdd:pfam16168 1 G A FSI SG GV AD N VL L EN G GS L T V VAG T S A T DT TV D KGG T L dv QS G G TA TGT V V NNG 56
auto_AIDA-I
NF033176 autotransporter adhesin AIDA-I;
52-296
1.47e-08
autotransporter adhesin AIDA-I;
Pssm-ID: 380183 [Multi-domain]
Cd Length: 1287
Bit Score: 58.90
E-value: 1.47e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 52 G T A NN T K IN PG G EQHIKEF G ISS NT E IN - GG Y QYI EM NG T A EYSVL N - D G Y Q I V QM GG A A NQ T T L NN G vlqvygaa N EPT 129
Cdd:NF033176 393 G Y A SG T L IN NS G RENVSNG G SAY NT I IN a GG N QYI YS NG E A SGTTV N t S G F Q R V NS GG T A TG T K L SG G -------- N QNV 464
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 130 IK GG RL I I ekdgitvf A AIEK GG LLE V KE GG L A FAVDQKA GG AIKTTTRAMEVFGT N RL G QFDIKD G IANNML L ENG G SL 209
Cdd:NF033176 465 SS GG KA I A -------- A EVYS GG KQT V YA GG E A SGTQIFD GG VVNVSGGSVSGASV N LN G RLNVFA G NVTGTI L NQE G RQ 536
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 210 RVEENDF A YN T TVDSG G LLE V MD GG T A T G VDKKA GG KLI VS TNALEVSGTNSK G -- QF SIKD G VSKNYELDD G SGLI V ME 287
Cdd:NF033176 537 YIYSGAS A TS T VANNE G REY V LS GG V A D G TVLNS GG LQA VS SGGSASATVINE G gs QF VYEG G NVTGTVIKN G GAIR V DS 616
....*....
gi 446476363 288 DTQ A IDTI L 296
Cdd:NF033176 617 GAS A LNIA L 625
PRK14849
PRK14849 autotransporter barrel domain-containing lipoprotein;
481-759
1.32e-05
autotransporter barrel domain-containing lipoprotein;
Pssm-ID: 184851 [Multi-domain]
Cd Length: 1806
Bit Score: 49.35
E-value: 1.32e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 481 N HQS D QL NV T G QAT G DFKIF V TDT G ASP A AGDSLTLVTTG GG DA A FTLGNAG G V V DI G T Y E YTL LD --- N GNHS W S L AEN 557
Cdd:PRK14849 1375 N SPT D KM NV K G DTQ G NTRVR V DNI G GVG A QTVNGIELIEV GG NS A GNFALTT G T V EA G A Y V YTL AK gkg N DEKN W Y L TSK 1454
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 558 RAQI TP - S T T D VL N maaa Q P L V F D A E LDT V - R ERL GS - VKGVSYDTAMW S SAINT R ------- NNVTTDAG A -------- 619
Cdd:PRK14849 1455 WDGV TP p D T P D PI N ---- N P P V V D P E GPS V y R PEA GS y ISNIAAANSLF S HRLHD R lgepqyi DSLHSQGS A ssmwmrhv 1530
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 620 - G F E QTLT G ------------ L T LG I D -- SRF S REESSTIR G LFF GY S -- HS DIGFD R G G --- K G NVDS Y TL G A YA G W -- 677
Cdd:PRK14849 1531 g G H E RSRA G dgqlntqanryv L Q LG G D la QWS S NAQDRWHL G VMA GY A nq HS NTQSN R V G yks D G RISG Y SA G L YA T W yq 1610
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446476363 678 -- EHQN GAYVD GVVKVDR F A N TI hgkm S NGATAFG DY S S N G AG A H VE S G FRWVD G ---------- L W S V R P YLAF T GFTT 745
Cdd:PRK14849 1611 nd ANKT GAYVD SWALYNW F D N SV ---- S SDNRSAD DY D S R G VT A S VE G G YTFEA G tfsgsegtln T W Y V Q P QAQI T WMGV 1686
330
....*....|....
gi 446476363 746 DGQ D Y T LSN G M R AD 759
Cdd:PRK14849 1687 KDS D H T RKD G T R IE 1700
Blast search parameters
Data Source:
Precalculated data, version = cdd.v.3.21
Preset Options: Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
