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Conserved domains on  [gi|446472819|ref|WP_000550673|]
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MULTISPECIES: YncE family protein [Enterobacteriaceae]

Protein Classification

YncE family protein( domain architecture ID 11465355)

YncE family protein contains repeats resembling the NHL (NCL-1, HT2A and LIN-41) and YVTN-type repeats, similar to DNA-binding beta-propeller protein YncE and Bacillus subtilis uncharacterized protein YwhL

CATH:  2.130.10.10
PubMed:  22120742|10607670
SCOP:  4002745

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
YncE COG3391
DNA-binding beta-propeller fold protein YncE [General function prediction only];
125-331 1.32e-22

DNA-binding beta-propeller fold protein YncE [General function prediction only];


:

Pssm-ID: 442618 [Multi-domain]  Cd Length: 237  Bit Score: 94.76  E-value: 1.32e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446472819 125 GRLVLDDRKRTEEVRPLQPRELVADDATNTVYISGIGKESVIWVVDGENIKLKTAIQNTGKMSTGLALDSKGKRLYTTNA 204
Cdd:COG3391    8 LVAVLLAVLALAALAVAVAALGLGGGGPLLAAASGGVVGAAVGGGGVALLAGLGLGAAAVADADGADAGADGRRLYVANS 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446472819 205 DGELIT-IDTADNKILSRKKLLDDgkehfFINISLDTANERAFITDSKAAEVLVVDTRNGNILAKVAAPESL-AVLFNPA 282
Cdd:COG3391   88 GSGRVSvIDLATGKVVATIPVGGG-----PRGLAVDPDGGRLYVADSGNGRVSVIDTATGKVVATIPVGAGPhGIAVDPD 162

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 446472819 283 RNEAYVTHRQAGKVS----VIDAKSYKVVKTFDTPTHPNSLALSADGKTLYVS 331
Cdd:COG3391  163 GKRLYVANSGSNTVSvivsVIDTATGKVVATIPVGGGPVGVAVSPDGRRLYVA 215
Vgb super family cl26743
Streptogramin lyase [Defense mechanisms];
40-161 1.18e-03

Streptogramin lyase [Defense mechanisms];


The actual alignment was detected with superfamily member COG4257:

Pssm-ID: 443399 [Multi-domain]  Cd Length: 270  Bit Score: 40.00  E-value: 1.18e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446472819  40 GKGAYEMAYSQQeNALWLATSQSRKldkggvVYRLDPVTLEVTQ-AIHNDLK-PFGATInnTTQ-TLWFGNTVNSAVTAI 116
Cdd:COG4257  144 GAGPYGIAVDPD-GNLWVTDFGANA------IGRIDPDTGTLTEyALPTPGAgPRGLAV--DPDgNLWVADTGSGRIGRF 214

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*
gi 446472819 117 DAKTGEVKgRLVLDDrkrteevRPLQPRELVADDAtNTVYISGIG 161
Cdd:COG4257  215 DPKTGTVT-EYPLPG-------GGARPYGVAVDGD-GRVWFAESG 250
 
Name Accession Description Interval E-value
YncE COG3391
DNA-binding beta-propeller fold protein YncE [General function prediction only];
125-331 1.32e-22

DNA-binding beta-propeller fold protein YncE [General function prediction only];


Pssm-ID: 442618 [Multi-domain]  Cd Length: 237  Bit Score: 94.76  E-value: 1.32e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446472819 125 GRLVLDDRKRTEEVRPLQPRELVADDATNTVYISGIGKESVIWVVDGENIKLKTAIQNTGKMSTGLALDSKGKRLYTTNA 204
Cdd:COG3391    8 LVAVLLAVLALAALAVAVAALGLGGGGPLLAAASGGVVGAAVGGGGVALLAGLGLGAAAVADADGADAGADGRRLYVANS 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446472819 205 DGELIT-IDTADNKILSRKKLLDDgkehfFINISLDTANERAFITDSKAAEVLVVDTRNGNILAKVAAPESL-AVLFNPA 282
Cdd:COG3391   88 GSGRVSvIDLATGKVVATIPVGGG-----PRGLAVDPDGGRLYVADSGNGRVSVIDTATGKVVATIPVGAGPhGIAVDPD 162

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 446472819 283 RNEAYVTHRQAGKVS----VIDAKSYKVVKTFDTPTHPNSLALSADGKTLYVS 331
Cdd:COG3391  163 GKRLYVANSGSNTVSvivsVIDTATGKVVATIPVGGGPVGVAVSPDGRRLYVA 215
NHL_like_6 cd14962
Uncharacterized NHL-repeat domain in bacterial proteins; The NHL (NCL-1, HT2A and LIN-41) ...
 189-330 2.13e-09

Uncharacterized NHL-repeat domain in bacterial proteins; The NHL (NCL-1, HT2A and LIN-41) repeat is found in multiple tandem copies, typically as 6 instances. It is about 40 residues long and resembles the WD repeat and other beta-propeller structures.


Pssm-ID: 271332 [Multi-domain]  Cd Length: 271  Bit Score: 57.60  E-value: 2.13e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446472819 189 GLALDSKGkRLYTTN-ADGELITIDTADNKIlsrkKLLDDGKEHFF---INISLDtANERAFITDSKAAEVLVVDtRNGN 264
Cdd:cd14962   16 GVAADGRG-RIYVADtGRGAVFVFDLPNGKV----FVIGNAGPNRFvspIGVAID-ANGNLYVSDAELGKVFVFD-RDGK 88

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446472819 265 ILAKVAA------PESLAVlfNPARNEAYVTHRQAGKVSVIDAKSyKVVKTFDTP-------THPNSLALSADGKtLYV 330
Cdd:cd14962   89 FLRAIGAgalfkrPTGIAV--DPAGKRLYVVDTLAHKVKVFDLDG-RLLFDIGKRgsgpgefNLPTDLAVDRDGN-LYV 163
PQQ_ABC_repeats TIGR03866
PQQ-dependent catabolism-associated beta-propeller protein; Members of this protein family ...
 151-331 4.07e-09

PQQ-dependent catabolism-associated beta-propeller protein; Members of this protein family consist of seven repeats each of the YVTN family beta-propeller repeat (see TIGR02276). Members occur invariably as part of a transport operon that is associated with PQQ-dependent catabolism of alcohols such as phenylethanol.


Pssm-ID: 274824 [Multi-domain]  Cd Length: 310  Bit Score: 56.97  E-value: 4.07e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446472819  151 ATNTVYISGiGKESVIWVVDGENIKLKTAIQnTGKMSTGLALDSKGKRLYTTNADGELI-TIDTADNKILsrkKLLDDGK 229
Cdd:TIGR03866   9 AAETAYVSN-EKDNTISVIDTATLKVTRTFP-VGQRPRGITFSKDGKLLYVCASDSDTIqVIDPATGEVL---HTLPSGP 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446472819  230 --EHFfiniSLDTANERAFITDSKAAEVLVVDTRNGNILAKV---AAPESLAVlfNPARNEAYVTHRQAGKVSVIDAKSY 304
Cdd:TIGR03866  84 dpEQF----ALHPNGKILYIANEDDALVTVIDIETRKVLAQIdvgVEPEGMAV--SPDGKIVVNTSETTNMAHWIDTATY 157

                         170       180
                  ....*....|....*....|....*..
gi 446472819  305 KVVKTFDTPTHPNSLALSADGKTLYVS 331
Cdd:TIGR03866 158 EIVDNTLVDARPRFAEFTADGKELWVS 184
PQQ_2 pfam13360
PQQ-like domain; This domain contains several repeats of the PQQ repeat.
 66-219 3.18e-04

PQQ-like domain; This domain contains several repeats of the PQQ repeat.


Pssm-ID: 433144 [Multi-domain]  Cd Length: 233  Bit Score: 41.62  E-value: 3.18e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446472819   66 DKGGVVYRLDPVTLEVtqaIHNDLKPFG-ATINNTTQTLWFGNTV-----NSAVTAIDAKTGEVKGRLVLDDRKRT---E 136
Cdd:pfam13360  80 AGDGSLIALDAADGRR---LWSYQRSGEpLALRSSGSPAVVGDTVvagfsSGKLVALDPATGKVRWEAPLAAPRGTnelE 156

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446472819  137 EVRPLQPRELVADDatnTVYISGIGKESVIWVVDGENIKLKTAIQNtgkmSTGLALDskGKRLYTTNADGELITIDTADN 216
Cdd:pfam13360 157 RLVDITGTPVVAGG---RVFASAYQGRLVAFDAATGRRLWTREISG----PNGPILD--GDLLYVVSDDGELYALDRATG 227


                  ...
gi 446472819  217 KIL 219
Cdd:pfam13360 228 AVV 230
Vgb COG4257
Streptogramin lyase [Defense mechanisms];
40-161 1.18e-03

Streptogramin lyase [Defense mechanisms];


Pssm-ID: 443399 [Multi-domain]  Cd Length: 270  Bit Score: 40.00  E-value: 1.18e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446472819  40 GKGAYEMAYSQQeNALWLATSQSRKldkggvVYRLDPVTLEVTQ-AIHNDLK-PFGATInnTTQ-TLWFGNTVNSAVTAI 116
Cdd:COG4257  144 GAGPYGIAVDPD-GNLWVTDFGANA------IGRIDPDTGTLTEyALPTPGAgPRGLAV--DPDgNLWVADTGSGRIGRF 214

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*
gi 446472819 117 DAKTGEVKgRLVLDDrkrteevRPLQPRELVADDAtNTVYISGIG 161
Cdd:COG4257  215 DPKTGTVT-EYPLPG-------GGARPYGVAVDGD-GRVWFAESG 250
 
Name Accession Description Interval E-value
YncE COG3391
DNA-binding beta-propeller fold protein YncE [General function prediction only];
125-331 1.32e-22

DNA-binding beta-propeller fold protein YncE [General function prediction only];


Pssm-ID: 442618 [Multi-domain]  Cd Length: 237  Bit Score: 94.76  E-value: 1.32e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446472819 125 GRLVLDDRKRTEEVRPLQPRELVADDATNTVYISGIGKESVIWVVDGENIKLKTAIQNTGKMSTGLALDSKGKRLYTTNA 204
Cdd:COG3391    8 LVAVLLAVLALAALAVAVAALGLGGGGPLLAAASGGVVGAAVGGGGVALLAGLGLGAAAVADADGADAGADGRRLYVANS 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446472819 205 DGELIT-IDTADNKILSRKKLLDDgkehfFINISLDTANERAFITDSKAAEVLVVDTRNGNILAKVAAPESL-AVLFNPA 282
Cdd:COG3391   88 GSGRVSvIDLATGKVVATIPVGGG-----PRGLAVDPDGGRLYVADSGNGRVSVIDTATGKVVATIPVGAGPhGIAVDPD 162

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 446472819 283 RNEAYVTHRQAGKVS----VIDAKSYKVVKTFDTPTHPNSLALSADGKTLYVS 331
Cdd:COG3391  163 GKRLYVANSGSNTVSvivsVIDTATGKVVATIPVGGGPVGVAVSPDGRRLYVA 215
YncE COG3391
DNA-binding beta-propeller fold protein YncE [General function prediction only];
62-303 8.22e-16

DNA-binding beta-propeller fold protein YncE [General function prediction only];


Pssm-ID: 442618 [Multi-domain]  Cd Length: 237  Bit Score: 75.89  E-value: 8.22e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446472819  62 SRKLDKGGVVYRLDPVTLEVTQAIHNDLKPFGATINNTTQTLWFGNTVNSAVTAIDAKTGEVKGRLVLDDRkrteevrpl 141
Cdd:COG3391   41 SGGVVGAAVGGGGVALLAGLGLGAAAVADADGADAGADGRRLYVANSGSGRVSVIDLATGKVVATIPVGGG--------- 111

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446472819 142 qPRELVADDATNTVYISGIGkESVIWVVDGENIKLKTAIqNTGKMSTGLALDSKGKRLYTTNA-DGELITIdtadnkils 220
Cdd:COG3391  112 -PRGLAVDPDGGRLYVADSG-NGRVSVIDTATGKVVATI-PVGAGPHGIAVDPDGKRLYVANSgSNTVSVI--------- 179

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446472819 221 rkkllddgkehffinisldtanerafitdskaaeVLVVDTRNGNILAKVAAPES-LAVLFNPARNEAYVTHRQAGK---- 295
Cdd:COG3391  180 ----------------------------------VSVIDTATGKVVATIPVGGGpVGVAVSPDGRRLYVANRGSNTsngg 225

                        250
                 ....*....|.
gi 446472819 296 ---VSVIDAKS 303
Cdd:COG3391  226 sntVSVIDLAT 236
YncE COG3391
DNA-binding beta-propeller fold protein YncE [General function prediction only];
68-216 3.62e-13

DNA-binding beta-propeller fold protein YncE [General function prediction only];


Pssm-ID: 442618 [Multi-domain]  Cd Length: 237  Bit Score: 68.18  E-value: 3.62e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446472819  68 GGVVYRLDPVTLEVTQAIHNDLKPFGATINNTTQTLWFGNTVNSAVTAIDAKTGEVKGRLVLDDrkrteevrplQPRELV 147
Cdd:COG3391   89 SGRVSVIDLATGKVVATIPVGGGPRGLAVDPDGGRLYVADSGNGRVSVIDTATGKVVATIPVGA----------GPHGIA 158

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446472819 148 ADDATNTVYISGIGKESV---IWVVDGENIKLKTAIqNTGKMSTGLALDSKGKRLYTTNA--------DGELITIDTADN 216
Cdd:COG3391  159 VDPDGKRLYVANSGSNTVsviVSVIDTATGKVVATI-PVGGGPVGVAVSPDGRRLYVANRgsntsnggSNTVSVIDLATL 237
Vgb COG4257
Streptogramin lyase [Defense mechanisms];
54-303 2.00e-09

Streptogramin lyase [Defense mechanisms];


Pssm-ID: 443399 [Multi-domain]  Cd Length: 270  Bit Score: 57.72  E-value: 2.00e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446472819  54 ALWLAtsqsrkLDKGGVVYRLDPVTLEVTQ-AIHNDLKPFGATINNTtQTLWFGNTVNSAVTAIDAKTGEVKgRLVLDDR 132
Cdd:COG4257   29 AVWFT------DQGGGRIGRLDPATGEFTEyPLGGGSGPHGIAVDPD-GNLWFTDNGNNRIGRIDPKTGEIT-TFALPGG 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446472819 133 KRteevrplQPRELVAdDATNTVYISGIGKeSVIWVVDGENIKLKT-AIQNTGKMSTGLALDSKGKRLYTTNADGELITI 211
Cdd:COG4257  101 GS-------NPHGIAF-DPDGNLWFTDQGG-NRIGRLDPATGEVTEfPLPTGGAGPYGIAVDPDGNLWVTDFGANAIGRI 171

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446472819 212 DTADNKIlSRKKLLDDGKEHFFINIsldTANERAFITDSKAAEVLVVDTRNGNI-----LAKVAAPESLAVlfnPARNEA 286
Cdd:COG4257  172 DPDTGTL-TEYALPTPGAGPRGLAV---DPDGNLWVADTGSGRIGRFDPKTGTVteyplPGGGARPYGVAV---DGDGRV 244

                        250
                 ....*....|....*..
gi 446472819 287 YVTHRQAGKVSVIDAKS 303
Cdd:COG4257  245 WFAESGANRIVRFDPDT 261
NHL_like_6 cd14962
Uncharacterized NHL-repeat domain in bacterial proteins; The NHL (NCL-1, HT2A and LIN-41) ...
 189-330 2.13e-09

Uncharacterized NHL-repeat domain in bacterial proteins; The NHL (NCL-1, HT2A and LIN-41) repeat is found in multiple tandem copies, typically as 6 instances. It is about 40 residues long and resembles the WD repeat and other beta-propeller structures.


Pssm-ID: 271332 [Multi-domain]  Cd Length: 271  Bit Score: 57.60  E-value: 2.13e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446472819 189 GLALDSKGkRLYTTN-ADGELITIDTADNKIlsrkKLLDDGKEHFF---INISLDtANERAFITDSKAAEVLVVDtRNGN 264
Cdd:cd14962   16 GVAADGRG-RIYVADtGRGAVFVFDLPNGKV----FVIGNAGPNRFvspIGVAID-ANGNLYVSDAELGKVFVFD-RDGK 88

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446472819 265 ILAKVAA------PESLAVlfNPARNEAYVTHRQAGKVSVIDAKSyKVVKTFDTP-------THPNSLALSADGKtLYV 330
Cdd:cd14962   89 FLRAIGAgalfkrPTGIAV--DPAGKRLYVVDTLAHKVKVFDLDG-RLLFDIGKRgsgpgefNLPTDLAVDRDGN-LYV 163
PQQ_ABC_repeats TIGR03866
PQQ-dependent catabolism-associated beta-propeller protein; Members of this protein family ...
 151-331 4.07e-09

PQQ-dependent catabolism-associated beta-propeller protein; Members of this protein family consist of seven repeats each of the YVTN family beta-propeller repeat (see TIGR02276). Members occur invariably as part of a transport operon that is associated with PQQ-dependent catabolism of alcohols such as phenylethanol.


Pssm-ID: 274824 [Multi-domain]  Cd Length: 310  Bit Score: 56.97  E-value: 4.07e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446472819  151 ATNTVYISGiGKESVIWVVDGENIKLKTAIQnTGKMSTGLALDSKGKRLYTTNADGELI-TIDTADNKILsrkKLLDDGK 229
Cdd:TIGR03866   9 AAETAYVSN-EKDNTISVIDTATLKVTRTFP-VGQRPRGITFSKDGKLLYVCASDSDTIqVIDPATGEVL---HTLPSGP 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446472819  230 --EHFfiniSLDTANERAFITDSKAAEVLVVDTRNGNILAKV---AAPESLAVlfNPARNEAYVTHRQAGKVSVIDAKSY 304
Cdd:TIGR03866  84 dpEQF----ALHPNGKILYIANEDDALVTVIDIETRKVLAQIdvgVEPEGMAV--SPDGKIVVNTSETTNMAHWIDTATY 157

                         170       180
                  ....*....|....*....|....*..
gi 446472819  305 KVVKTFDTPTHPNSLALSADGKTLYVS 331
Cdd:TIGR03866 158 EIVDNTLVDARPRFAEFTADGKELWVS 184
PQQ_ABC_repeats TIGR03866
PQQ-dependent catabolism-associated beta-propeller protein; Members of this protein family ...
 102-330 5.50e-08

PQQ-dependent catabolism-associated beta-propeller protein; Members of this protein family consist of seven repeats each of the YVTN family beta-propeller repeat (see TIGR02276). Members occur invariably as part of a transport operon that is associated with PQQ-dependent catabolism of alcohols such as phenylethanol.


Pssm-ID: 274824 [Multi-domain]  Cd Length: 310  Bit Score: 53.51  E-value: 5.50e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446472819  102 TLWFGNTVNSAVTAIDAKTGEVKGRLVLDDRkrteevrplqPRELVADDATNTVYISGiGKESVIWVVDGENIKLktaiq 181
Cdd:TIGR03866  12 TAYVSNEKDNTISVIDTATLKVTRTFPVGQR----------PRGITFSKDGKLLYVCA-SDSDTIQVIDPATGEV----- 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446472819  182 nTGKMSTG-----LALDSKGKRLYTTNADGELIT-IDTADNKILSR---------KKLLDDGKehFFINISlDTANERAF 246
Cdd:TIGR03866  76 -LHTLPSGpdpeqFALHPNGKILYIANEDDALVTvIDIETRKVLAQidvgvepegMAVSPDGK--IVVNTS-ETTNMAHW 151

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446472819  247 ItDSKAAEVL---VVDTRngnilakvaaPESLAvlFNPARNEAYVTHRQAGKVSVIDAKSYKVVK--TFDTP-THPNSL- 319
Cdd:TIGR03866 152 I-DTATYEIVdntLVDAR----------PRFAE--FTADGKELWVSSEIGGTVTVIDVATRKVIKkiTFAIPgVHPEKVq 218

                         250
                  ....*....|....*
gi 446472819  320 ----ALSADGKTLYV 330
Cdd:TIGR03866 219 pvgiKLTKDGKTAFV 233
YvrE COG3386
Sugar lactone lactonase YvrE [Carbohydrate transport and metabolism]; Sugar lactone lactonase ...
 150-331 2.92e-07

Sugar lactone lactonase YvrE [Carbohydrate transport and metabolism]; Sugar lactone lactonase YvrE is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway


Pssm-ID: 442613 [Multi-domain]  Cd Length: 266  Bit Score: 51.05  E-value: 2.92e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446472819 150 DATNTVYISGIgKESVIWVVDGENIKLKTaIQNTGKMSTGLALDSKGkRLYTTNADGELITIDTADNKIlsrKKLLDD-G 228
Cdd:COG3386   16 DPDGRLYWVDI-PGGRIHRYDPDGGAVEV-FAEPSGRPNGLAFDPDG-RLLVADHGRGLVRFDPADGEV---TVLADEyG 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446472819 229 KEHFFINisldtanerafitDskaaevLVVDtRNGNIlakvaapeslavlfnparneaYVT----HRQAGKVSVIDAKSy 304
Cdd:COG3386   90 KPLNRPN-------------D------GVVD-PDGRL---------------------YFTdmgeYLPTGALYRVDPDG- 127

                        170       180
                 ....*....|....*....|....*..
gi 446472819 305 KVVKTFDTPTHPNSLALSADGKTLYVS 331
Cdd:COG3386  128 SLRVLADGLTFPNGIAFSPDGRTLYVA 154
8prop_hemeD1_NirF cd20778
eight-bladed heme d1-binding beta-propeller domain in cytochrome cd1 nitrate reductase NirF; ...
 69-332 5.07e-07

eight-bladed heme d1-binding beta-propeller domain in cytochrome cd1 nitrate reductase NirF; Denitrification is a process that enables biofilm formation of the opportunistic human pathogen Pseudomonas aeruginosa, making it more resilient to antibiotics and highly adaptable to different habitats. During denitrification, nitrate (Nar), nitrite (Nir), nitric oxide (Nor), and nitrous oxide (Nos) reductases catalyze the reaction cascade of NO3- -> NO2- -> NO -> N2O -> N2. The integral membrane proteins NorC, NorB, and NosR form the core assembly platform that binds the nitrate reductase NarGHI and the periplasmic cytochrome cd1 (nitrite reductase) NirS via its maturation factor NirF. The nirFDLGHJE genes encode proteins required for heme d1 biosynthesis. NirS, NirF, and NirN, the monomeric dihydro-heme d1 dehydrogenase form a stable complex during nitrite reductase maturation. The nitrite reductase NirS is bound to the denitrification supercomplex via NorB, while the electron donor system NirM and the enzyme maturation machinery NirN-NirF-NirQ, interacting with NirS, are bound via NorC.


Pssm-ID: 467722 [Multi-domain]  Cd Length: 381  Bit Score: 51.13  E-value: 5.07e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446472819  69 GVVYRLDPVTLEVTQAIHNDLKPFGATINNTTQTLWFGNTVNSAVTAIDAKTGEVkgrlvLDDRKRTEEVRPLQPRELVA 148
Cdd:cd20778   72 GGLSKVDLLTLKVVARVKQSGNSIGGAISQDGRYVAVANYDPGGVKILDADTLKV-----LADIPAGSKGGGQRSRVVGL 146

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446472819 149 DDATNTVYISGIGKESVIWVVD--GENIKLKTAIQNTGKMSTGlALDSKGKRLYTT---NADGeLITIDTADNKILSRKK 223
Cdd:cd20778  147 VDAPGNRFIFSLMDADEIWVLDasDPDFPVVKKFKDIGRMPYD-ALITPDGRYYIAglfNSDG-VGLLDLWKPERGVRRI 224

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446472819 224 LLDDGKE----------HF-FINIsldtANERAFITDSKAAEVLVVDTRN----------GNILAKVAAPES--LAVLFN 280
Cdd:cd20778  225 LLDYGKGeeklpvykmpHLeGWAV----AGDKAFVPAVGEHRVLVYDTNDwkfiksiplaGQPVFAVARPDGryVWVNFS 300

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 446472819 281 PARNeayvthrqaGKVSVIDAKSYKVVKTFDTP---THpnsLALSADGKTLYVSV 332
Cdd:cd20778  301 GPDN---------DTVQVIDTKTLKVVKTLEPGkrvLH---MEFTPRGEAVYISV 343
PQQ_ABC_repeats TIGR03866
PQQ-dependent catabolism-associated beta-propeller protein; Members of this protein family ...
 282-339 2.22e-06

PQQ-dependent catabolism-associated beta-propeller protein; Members of this protein family consist of seven repeats each of the YVTN family beta-propeller repeat (see TIGR02276). Members occur invariably as part of a transport operon that is associated with PQQ-dependent catabolism of alcohols such as phenylethanol.


Pssm-ID: 274824 [Multi-domain]  Cd Length: 310  Bit Score: 48.88  E-value: 2.22e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 446472819  282 ARNEAYVTHRQAGKVSVIDAKSYKVVKTFDTPTHPNSLALSADGKTLYVSVKQKSTKQ 339
Cdd:TIGR03866   9 AAETAYVSNEKDNTISVIDTATLKVTRTFPVGQRPRGITFSKDGKLLYVCASDSDTIQ 66
8prop_heme_binding_protein cd20718
eight-bladed beta-propeller heme-binding domain in cytochrome cd1 and similar proteins; ...
 168-318 1.01e-05

eight-bladed beta-propeller heme-binding domain in cytochrome cd1 and similar proteins; Members here contain an 8-bladed beta-propeller heme-binding domain in cytochrome cd1 (nitrite reductase) and similar proteins including NirN and NirF. During denitrification, nitrate (Nar), nitrite (Nir), nitric oxide (Nor), and nitrous oxide (Nos) reductases catalyze the reaction cascade of NO(3-)-> NO(2-)-> NO -> N2O -> N2. The integral membrane proteins NorC, NorB, and NosR form the core assembly platform that binds the nitrate reductase NarGHI and the periplasmic nitrite reductase NirS via its maturation factor NirF. NirN and NirF form a stable complex with the nitrite reductase NirS during enzyme maturation. NirF is involved in heme d1 insertion.


Pssm-ID: 467720 [Multi-domain]  Cd Length: 380  Bit Score: 46.95  E-value: 1.01e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446472819 168 VVDGENIKLKTAIQNTG---------KMSTGLALDSKGKRLYTTNADGELITIDTADNKILSRKKLLDDGKEH--FFIni 236
Cdd:cd20718  126 ILDADTLEPLKVIPTTGvnddgiiesRVGAILETPPGPYFLVALKDAGSVWVIDYSDPDGNKVTDIGNIGRPLhdAFL-- 203

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446472819 237 sldTANERAFITDSKAAEVL-VVDTRNGNILAKVAA-----PESLAVLFNpaRNEAYVTHRQAGKVSVIDAKSYKVVKTF 310
Cdd:cd20718  204 ---DPDGRYFIVASQGSNTMwVLDLKTGKVVARIPTgktphPGPGATWGR--KGVTATPHLGEGIVTVWDLDTWKPVKYI 278

                        170
                 ....*....|....*
gi 446472819 311 DTP-------THPNS 318
Cdd:cd20718  279 PTPgpgrfvrTHPSS 293
Pgl COG2706
6-phosphogluconolactonase, cycloisomerase 2 family [Carbohydrate transport and metabolism];
116-331 3.05e-05

6-phosphogluconolactonase, cycloisomerase 2 family [Carbohydrate transport and metabolism];


Pssm-ID: 442025 [Multi-domain]  Cd Length: 352  Bit Score: 45.28  E-value: 3.05e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446472819 116 IDAKTGEvkgrlvLDDRKRTEEVRplQPRELVADDATNTVYISGIGKESVIWV--VDGENIKLKTAiqntGKMSTG---- 189
Cdd:COG2706   28 LDTATGE------LTLLGLVAALG--NPSFLALSPDGRFLYAVNEVDDGGVSAfrIDPADGTLTLL----NTVSSGgasp 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446472819 190 --LALDSKGKRLYTTN------------ADGELIT-IDTADNKILSRKKLLDDGKEHFFINISLDtaNERAFITDSKAAE 254
Cdd:COG2706   96 chLSVDPDGRFLFVANygggsvsvfpidADGSLGEpVQVIQHEGSGPNPERQEGPHAHSVVFDPD--GRFLYVPDLGTDR 173

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446472819 255 VLV--VDTRNGNiLAKVAA--------PESLAvlFNPARNEAYVTHRQAGKVSV--IDAK--SYKVVKTFDT-------P 313
Cdd:COG2706  174 IYVyrLDPATGK-LPEPPEvslppgsgPRHLA--FHPNGRFAYVINELDSTVSVyaYDAAtgTLTLIQTVSTlpedftgE 250

                        250
                 ....*....|....*...
gi 446472819 314 THPNSLALSADGKTLYVS 331
Cdd:COG2706  251 NWAADIHISPDGRFLYVS 268
8prop_heme_binding_protein cd20718
eight-bladed beta-propeller heme-binding domain in cytochrome cd1 and similar proteins; ...
 245-332 4.54e-05

eight-bladed beta-propeller heme-binding domain in cytochrome cd1 and similar proteins; Members here contain an 8-bladed beta-propeller heme-binding domain in cytochrome cd1 (nitrite reductase) and similar proteins including NirN and NirF. During denitrification, nitrate (Nar), nitrite (Nir), nitric oxide (Nor), and nitrous oxide (Nos) reductases catalyze the reaction cascade of NO(3-)-> NO(2-)-> NO -> N2O -> N2. The integral membrane proteins NorC, NorB, and NosR form the core assembly platform that binds the nitrate reductase NarGHI and the periplasmic nitrite reductase NirS via its maturation factor NirF. NirN and NirF form a stable complex with the nitrite reductase NirS during enzyme maturation. NirF is involved in heme d1 insertion.


Pssm-ID: 467720 [Multi-domain]  Cd Length: 380  Bit Score: 45.02  E-value: 4.54e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446472819 245 AFITDSKAAEVLVVDTRNGNILAKV----AAPESlaVLFNPARNEAYVTHRQaGKVSVIDAKSYKVVKTFDTPTHPNSLA 320
Cdd:cd20718   30 MVVVERDAGSVLVIDGSTHEVLGRIddggAQVHV--VVFSPDGRFAYVISRD-GWLTKIDLYTLRPVASIRIGVNSRGIA 106

                         90
                 ....*....|..
gi 446472819 321 LSADGKtlYVSV 332
Cdd:cd20718  107 LSDDGK--YVIA 116
YvrE COG3386
Sugar lactone lactonase YvrE [Carbohydrate transport and metabolism]; Sugar lactone lactonase ...
 67-289 4.80e-05

Sugar lactone lactonase YvrE [Carbohydrate transport and metabolism]; Sugar lactone lactonase YvrE is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway


Pssm-ID: 442613 [Multi-domain]  Cd Length: 266  Bit Score: 44.50  E-value: 4.80e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446472819  67 KGGVVYRLDPVTLEVTQAIHNDLKPFGATINNtTQTLWFGNTvNSAVTAIDAKTGEVkgRLVLDDRkrteEVRPLQPREL 146
Cdd:COG3386   27 PGGRIHRYDPDGGAVEVFAEPSGRPNGLAFDP-DGRLLVADH-GRGLVRFDPADGEV--TVLADEY----GKPLNRPNDG 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446472819 147 VADDAtNTVYISGIGKES---VIWVVDGENiKLKTAIQNTGkMSTGLALDSKGKRLYTTN-ADGELITIDTADNKILSRK 222
Cdd:COG3386   99 VVDPD-GRLYFTDMGEYLptgALYRVDPDG-SLRVLADGLT-FPNGIAFSPDGRTLYVADtGAGRIYRFDLDADGTLGNR 175

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446472819 223 KLLDDGKEHFFI--NISLDtANERAFITDSKAAEVLVVDtRNGNILAKVAAPESL--AVLFN-PARNEAYVT 289
Cdd:COG3386  176 RVFADLPDGPGGpdGLAVD-ADGNLWVALWGGGGVVRFD-PDGELLGRIELPERRptNVAFGgPDLRTLYVT 245
8prop_hemeD1_cyt_cd1-like cd20785
eight-bladed heme d1-binding beta-propeller domain in cytochrome cd1 nitrate reductase and ...
 166-331 9.64e-05

eight-bladed heme d1-binding beta-propeller domain in cytochrome cd1 nitrate reductase and similar proteins; Cytochrome cd1 (cyt cd1) nitrite reductase catalyzes in vitro the reduction of molecular oxygen to water and the reduction of nitrite to nitric oxide). It is a dimer of two identical subunits of 60 kDa, each containing one c and one d1 heme group. The c heme is the electron accepting pole of the molecule and is reduced in vitro by either azurin or cytochrome c551. The d1 heme is the site where nitrite, and oxygen reduction occur. NiR is a key denitrification enzyme, which controls the rate of the production of toxic nitric oxide (NO) and ultimately regulates the release of NO into the atmosphere. The two types of heme are located in separate domains whose arrangement suggests a mechanism requiring domain movement during catalysis.


Pssm-ID: 467729 [Multi-domain]  Cd Length: 412  Bit Score: 43.82  E-value: 9.64e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446472819 166 IWVVDGENIKLK-TAIQNTGKMSTGLALDSKGKRLYTTNADGELIT-IDTADNKILsrKKLLDDGKEH------------ 231
Cdd:cd20785  194 VWIVDLDKPGMPvTKIKNVGRHLHDAFLSPDGRYLMVASYDDNKNAvIDLKEKKVV--KKIPAGCQPHlgsgavvkvggr 271

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446472819 232 ---FFINISldtanerafiTDSKAAEVLVVDTRNGNILA--KVAAP-ESLAVlfNParNEAYV------THRQAGKVSVI 299
Cdd:cd20785  272 llgFGTNIG----------SCDDKTVVTVWDMDTFEVVKqiPVSGPtESPAA--HP--NAPYVavdivgKDPRARKIQLI 337

                        170       180       190
                 ....*....|....*....|....*....|..
gi 446472819 300 DAKSYKVVKTFDTPTHPNSLALSADGKTLYVS 331
Cdd:cd20785  338 DKNTLEVVKTLDVGGHSHFPEYTADGDYLYVS 369
8prop_heme_binding_protein cd20718
eight-bladed beta-propeller heme-binding domain in cytochrome cd1 and similar proteins; ...
 156-314 1.19e-04

eight-bladed beta-propeller heme-binding domain in cytochrome cd1 and similar proteins; Members here contain an 8-bladed beta-propeller heme-binding domain in cytochrome cd1 (nitrite reductase) and similar proteins including NirN and NirF. During denitrification, nitrate (Nar), nitrite (Nir), nitric oxide (Nor), and nitrous oxide (Nos) reductases catalyze the reaction cascade of NO(3-)-> NO(2-)-> NO -> N2O -> N2. The integral membrane proteins NorC, NorB, and NosR form the core assembly platform that binds the nitrate reductase NarGHI and the periplasmic nitrite reductase NirS via its maturation factor NirF. NirN and NirF form a stable complex with the nitrite reductase NirS during enzyme maturation. NirF is involved in heme d1 insertion.


Pssm-ID: 467720 [Multi-domain]  Cd Length: 380  Bit Score: 43.48  E-value: 1.19e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446472819 156 YISGIGKESVIWVVDGENIKLKTAIQnTGKM---STGlALDSKGKRLYTTNADGELIT-IDTADNKILSRKKLLDDGkeh 231
Cdd:cd20718  210 FIVASQGSNTMWVLDLKTGKVVARIP-TGKTphpGPG-ATWGRKGVTATPHLGEGIVTvWDLDTWKPVKYIPTPGPG--- 284

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446472819 232 FFINISLDT---ANERAFITDsKAAEVLVVDTRNgNILAKVAAPE----SLAVLFNPARNEAYVTHRQAGKVSVIDAKSY 304
Cdd:cd20718  285 RFVRTHPSSpyvWADTVFGPE-NADEIYVIDKET-LKVVKTLIPKpgkrALHPEFTRDGKYVYVSVWDGGEVVVYDAETL 362

                        170
                 ....*....|..
gi 446472819 305 KVVKTFD--TPT 314
Cdd:cd20718  363 ELVKRIPaeTPT 374
PQQ_2 pfam13360
PQQ-like domain; This domain contains several repeats of the PQQ repeat.
 66-219 3.18e-04

PQQ-like domain; This domain contains several repeats of the PQQ repeat.


Pssm-ID: 433144 [Multi-domain]  Cd Length: 233  Bit Score: 41.62  E-value: 3.18e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446472819   66 DKGGVVYRLDPVTLEVtqaIHNDLKPFG-ATINNTTQTLWFGNTV-----NSAVTAIDAKTGEVKGRLVLDDRKRT---E 136
Cdd:pfam13360  80 AGDGSLIALDAADGRR---LWSYQRSGEpLALRSSGSPAVVGDTVvagfsSGKLVALDPATGKVRWEAPLAAPRGTnelE 156

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446472819  137 EVRPLQPRELVADDatnTVYISGIGKESVIWVVDGENIKLKTAIQNtgkmSTGLALDskGKRLYTTNADGELITIDTADN 216
Cdd:pfam13360 157 RLVDITGTPVVAGG---RVFASAYQGRLVAFDAATGRRLWTREISG----PNGPILD--GDLLYVVSDDGELYALDRATG 227


                  ...
gi 446472819  217 KIL 219
Cdd:pfam13360 228 AVV 230
8prop_hemeD1_NirF cd20778
eight-bladed heme d1-binding beta-propeller domain in cytochrome cd1 nitrate reductase NirF; ...
 245-331 1.08e-03

eight-bladed heme d1-binding beta-propeller domain in cytochrome cd1 nitrate reductase NirF; Denitrification is a process that enables biofilm formation of the opportunistic human pathogen Pseudomonas aeruginosa, making it more resilient to antibiotics and highly adaptable to different habitats. During denitrification, nitrate (Nar), nitrite (Nir), nitric oxide (Nor), and nitrous oxide (Nos) reductases catalyze the reaction cascade of NO3- -> NO2- -> NO -> N2O -> N2. The integral membrane proteins NorC, NorB, and NosR form the core assembly platform that binds the nitrate reductase NarGHI and the periplasmic cytochrome cd1 (nitrite reductase) NirS via its maturation factor NirF. The nirFDLGHJE genes encode proteins required for heme d1 biosynthesis. NirS, NirF, and NirN, the monomeric dihydro-heme d1 dehydrogenase form a stable complex during nitrite reductase maturation. The nitrite reductase NirS is bound to the denitrification supercomplex via NorB, while the electron donor system NirM and the enzyme maturation machinery NirN-NirF-NirQ, interacting with NirS, are bound via NorC.


Pssm-ID: 467722 [Multi-domain]  Cd Length: 381  Bit Score: 40.73  E-value: 1.08e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446472819 245 AFITDSKAAEVLVVDTRNGNILAKVaapESLAVL------FNPARNEAYVTHRQaGKVSVIDAKSYKVVKTFDTPTHPNS 318
Cdd:cd20778   21 GVVVEREAGSVFVVDRSKHESLGRI---EGLGNLshatmvFSRDGRYAYVIGRD-GGLSKVDLLTLKVVARVKQSGNSIG 96

                         90
                 ....*....|...
gi 446472819 319 LALSADGKTLYVS 331
Cdd:cd20778   97 GAISQDGRYVAVA 109
Vgb COG4257
Streptogramin lyase [Defense mechanisms];
40-161 1.18e-03

Streptogramin lyase [Defense mechanisms];


Pssm-ID: 443399 [Multi-domain]  Cd Length: 270  Bit Score: 40.00  E-value: 1.18e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446472819  40 GKGAYEMAYSQQeNALWLATSQSRKldkggvVYRLDPVTLEVTQ-AIHNDLK-PFGATInnTTQ-TLWFGNTVNSAVTAI 116
Cdd:COG4257  144 GAGPYGIAVDPD-GNLWVTDFGANA------IGRIDPDTGTLTEyALPTPGAgPRGLAV--DPDgNLWVADTGSGRIGRF 214

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*
gi 446472819 117 DAKTGEVKgRLVLDDrkrteevRPLQPRELVADDAtNTVYISGIG 161
Cdd:COG4257  215 DPKTGTVT-EYPLPG-------GGARPYGVAVDGD-GRVWFAESG 250
PQQ_2 pfam13360
PQQ-like domain; This domain contains several repeats of the PQQ repeat.
 187-307 1.35e-03

PQQ-like domain; This domain contains several repeats of the PQQ repeat.


Pssm-ID: 433144 [Multi-domain]  Cd Length: 233  Bit Score: 39.69  E-value: 1.35e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446472819  187 STGLALDskGKRLYTTNADGELITIDTADNKILSRKKLldDGkehfFINISLDTANERAFITDSKAAeVLVVDTRNGNIL 266
Cdd:pfam13360  26 GGGVAVD--GGRLFVATGGGQLVALDAATGKLLWRQTL--SG----EVLGAPLVAGGRVFVVAGDGS-LIALDAADGRRL 96

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 446472819  267 AKVAAPESLAVLFNPA-----RNEAYVtHRQAGKVSVIDAKSYKVV 307
Cdd:pfam13360  97 WSYQRSGEPLALRSSGspavvGDTVVA-GFSSGKLVALDPATGKVR 141
YncE COG3391
DNA-binding beta-propeller fold protein YncE [General function prediction only];
38-121 1.45e-03

DNA-binding beta-propeller fold protein YncE [General function prediction only];


Pssm-ID: 442618 [Multi-domain]  Cd Length: 237  Bit Score: 39.68  E-value: 1.45e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446472819  38 AVGKGAYEMAYSQQENALWLATSQSRKLDKggVVYRLDPVTLEVTQAIHNDLKPFGATINNTTQTLWFGNTVNSA----- 112
Cdd:COG3391  149 PVGAGPHGIAVDPDGKRLYVANSGSNTVSV--IVSVIDTATGKVVATIPVGGGPVGVAVSPDGRRLYVANRGSNTsnggs 226

                         90
                 ....*....|.
gi 446472819 113 --VTAIDAKTG 121
Cdd:COG3391  227 ntVSVIDLATL 237
beta_rpt_yvtn TIGR02276
40-residue YVTN family beta-propeller repeat; This repeat of about 40 amino acids is found in ...
 281-322 9.01e-03

40-residue YVTN family beta-propeller repeat; This repeat of about 40 amino acids is found in up to 14 copies per protein. Archaea Methanosarcina mazei and Methanosarcina acetivorans each have over 10 genes that encode tandem copies of this repeat, which is also found in other species. PSIPRED predicts with high confidence that each 40-residue repeats contains four beta strands. This model overlaps somewhat with the NHL repeat (pfam01436) and also shows sequence similarity to the WD domain, G-beta repeat (pfam00400).


Pssm-ID: 213697 [Multi-domain]  Cd Length: 42  Bit Score: 33.81  E-value: 9.01e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 446472819  281 PARNEAYVTHRQAGKVSVIDAKSYKVVKTFDTPTHPNSLALS 322
Cdd:TIGR02276   1 PDGTKLYVTNSGSNTVSVIDTATNKVIATIPVGGYPFGVAVS 42
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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