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Conserved domains on  [gi|446471354|ref|WP_000549208|]
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MULTISPECIES: signal peptidase II [Staphylococcus]

Protein Classification

signal peptidase II( domain architecture ID 10001765)

signal peptidase II specifically catalyzes the removal of signal peptides from membrane prolipoproteins; it belongs to the peptidase family A8

EC:  3.4.23.36
Gene Ontology:  GO:0004190|GO:0006508
MEROPS:  A8
PubMed:  31214988

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
LspA COG0597
Lipoprotein signal peptidase [Cell wall/membrane/envelope biogenesis, Intracellular ...
 11-158 9.21e-48

Lipoprotein signal peptidase [Cell wall/membrane/envelope biogenesis, Intracellular trafficking, secretion, and vesicular transport];


:

Pssm-ID: 440362 [Multi-domain]  Cd Length: 151  Bit Score: 151.80  E-value: 9.21e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446471354  11 ILIAVFVVIFDQVTKYIIATTMKIGDSFEVIPHFLNITSHRNNGAAWGILSGKMTFFFIITIIILIALVYFFIKDAQYNL 90
Cdd:COG0597    4 LLLALLVLLLDQLTKLWVVANLALGESIPVIGGFFNLTYVENTGAAFGLLAGAGWLLIILALVVLVGLLYYLRRLKKRSK 83

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446471354  91 FMQVAISLLFAGALGNFIDRVLTGEVVDFIDTNIFGYDFPIFNIADSSLTIGVILIIIALLKDTSNKK 158
Cdd:COG0597   84 LLALALGLILGGALGNLIDRLFYGYVVDFIDFHIGGWHWPIFNVADIAITIGVILLLLDSLFGKKKKK 151
 
Name Accession Description Interval E-value
LspA COG0597
Lipoprotein signal peptidase [Cell wall/membrane/envelope biogenesis, Intracellular ...
 11-158 9.21e-48

Lipoprotein signal peptidase [Cell wall/membrane/envelope biogenesis, Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 440362 [Multi-domain]  Cd Length: 151  Bit Score: 151.80  E-value: 9.21e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446471354  11 ILIAVFVVIFDQVTKYIIATTMKIGDSFEVIPHFLNITSHRNNGAAWGILSGKMTFFFIITIIILIALVYFFIKDAQYNL 90
Cdd:COG0597    4 LLLALLVLLLDQLTKLWVVANLALGESIPVIGGFFNLTYVENTGAAFGLLAGAGWLLIILALVVLVGLLYYLRRLKKRSK 83

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446471354  91 FMQVAISLLFAGALGNFIDRVLTGEVVDFIDTNIFGYDFPIFNIADSSLTIGVILIIIALLKDTSNKK 158
Cdd:COG0597   84 LLALALGLILGGALGNLIDRLFYGYVVDFIDFHIGGWHWPIFNVADIAITIGVILLLLDSLFGKKKKK 151
Peptidase_A8 pfam01252
Signal peptidase (SPase) II;
13-152 1.36e-42

Signal peptidase (SPase) II;


Pssm-ID: 460136 [Multi-domain]  Cd Length: 140  Bit Score: 138.37  E-value: 1.36e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446471354   13 IAVFVVIFDQVTKYIIATTMKIGDSFEVIPHFLNITSHRNNGAAWGILSGKMTFFFIITIIILIALVYFFIKDAQYNLFM 92
Cdd:pfam01252   1 IALLLLLLDQLTKLLIVKNLKLGEPIEVIPGFFNLTYVENTGAAFGLLAGQRWLLIILTLVAIILLIYLLLKLKKKSRLL 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 446471354   93 QVAISLLFAGALGNFIDRVLTGEVVDFIDTNIFGYDFPIFNIADSSLTIGVILIIIALLK 152
Cdd:pfam01252  81 RIALALILGGALGNLIDRLFYGYVVDFIDFHIGFINFPVFNVADIAITVGVILLIIDLLF 140
PRK14791 PRK14791
lipoprotein signal peptidase; Provisional
 11-152 1.13e-31

lipoprotein signal peptidase; Provisional


Pssm-ID: 237817 [Multi-domain]  Cd Length: 146  Bit Score: 110.80  E-value: 1.13e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446471354  11 ILIAVFVVIFDQVTKYIIATTMKIGDSFEVIPHFLNITSHRNNGAAWGILSGKMTFFFIITIIILIALVYFFIKDAQYNL 90
Cdd:PRK14791   3 IIIIILGIFLDQLTKIWALKNLASGGDIPVIKNFFSLTYVENRGAAFGILQNKTLFLILITIIVILGLIYYIIKYKPTSK 82

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446471354  91 FMQVAISLLFAGALGNFIDRVLTGEVVDFIDTNIFGYDFPIFNIADSSLTIGVILIIIALLK 152
Cdd:PRK14791  83 LYKISLSLIISGAIGNLIDRIRYGYVVDFIDFHFKDYYFPVFNVADILVVVGTILLAIYILK 144
lspA TIGR00077
lipoprotein signal peptidase; Alternate name: lipoprotein signal peptidase [Protein fate, ...
 12-160 1.75e-26

lipoprotein signal peptidase; Alternate name: lipoprotein signal peptidase [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 272893 [Multi-domain]  Cd Length: 166  Bit Score: 98.20  E-value: 1.75e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446471354   12 LIAVFVVIFDQVTKYIIATTMKIGDSFEV-IPHFLNITSHRNNGAAWGILS---GKMTFFFIITIIILIALVYFFIKDAQ 87
Cdd:TIGR00077  14 LVAILFIGFDQLSKYLVLQNFDLGETYFVaFSGVFNITYVRNTGAAFSLLAdqgGQVYFLKGLAIAISLGLFVFLLRYKE 93

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446471354   88 YNLFMQVAISLLFAGALGNFIDRVLTGEVVDFIDTNIFGYDFPIFNIADSSLTIGVILIIIALLKDTSNKKEK 160
Cdd:TIGR00077  94 LFKITNIAFGLIFGGALGNFIDRLVRGGVVDFFDFYFGNYHFPIFNFADSSICIGVILLLLYFFFPKRKKKKD 166
 
Name Accession Description Interval E-value
LspA COG0597
Lipoprotein signal peptidase [Cell wall/membrane/envelope biogenesis, Intracellular ...
 11-158 9.21e-48

Lipoprotein signal peptidase [Cell wall/membrane/envelope biogenesis, Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 440362 [Multi-domain]  Cd Length: 151  Bit Score: 151.80  E-value: 9.21e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446471354  11 ILIAVFVVIFDQVTKYIIATTMKIGDSFEVIPHFLNITSHRNNGAAWGILSGKMTFFFIITIIILIALVYFFIKDAQYNL 90
Cdd:COG0597    4 LLLALLVLLLDQLTKLWVVANLALGESIPVIGGFFNLTYVENTGAAFGLLAGAGWLLIILALVVLVGLLYYLRRLKKRSK 83

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446471354  91 FMQVAISLLFAGALGNFIDRVLTGEVVDFIDTNIFGYDFPIFNIADSSLTIGVILIIIALLKDTSNKK 158
Cdd:COG0597   84 LLALALGLILGGALGNLIDRLFYGYVVDFIDFHIGGWHWPIFNVADIAITIGVILLLLDSLFGKKKKK 151
Peptidase_A8 pfam01252
Signal peptidase (SPase) II;
13-152 1.36e-42

Signal peptidase (SPase) II;


Pssm-ID: 460136 [Multi-domain]  Cd Length: 140  Bit Score: 138.37  E-value: 1.36e-42
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446471354   13 IAVFVVIFDQVTKYIIATTMKIGDSFEVIPHFLNITSHRNNGAAWGILSGKMTFFFIITIIILIALVYFFIKDAQYNLFM 92
Cdd:pfam01252   1 IALLLLLLDQLTKLLIVKNLKLGEPIEVIPGFFNLTYVENTGAAFGLLAGQRWLLIILTLVAIILLIYLLLKLKKKSRLL 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 446471354   93 QVAISLLFAGALGNFIDRVLTGEVVDFIDTNIFGYDFPIFNIADSSLTIGVILIIIALLK 152
Cdd:pfam01252  81 RIALALILGGALGNLIDRLFYGYVVDFIDFHIGFINFPVFNVADIAITVGVILLIIDLLF 140
PRK14791 PRK14791
lipoprotein signal peptidase; Provisional
 11-152 1.13e-31

lipoprotein signal peptidase; Provisional


Pssm-ID: 237817 [Multi-domain]  Cd Length: 146  Bit Score: 110.80  E-value: 1.13e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446471354  11 ILIAVFVVIFDQVTKYIIATTMKIGDSFEVIPHFLNITSHRNNGAAWGILSGKMTFFFIITIIILIALVYFFIKDAQYNL 90
Cdd:PRK14791   3 IIIIILGIFLDQLTKIWALKNLASGGDIPVIKNFFSLTYVENRGAAFGILQNKTLFLILITIIVILGLIYYIIKYKPTSK 82

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446471354  91 FMQVAISLLFAGALGNFIDRVLTGEVVDFIDTNIFGYDFPIFNIADSSLTIGVILIIIALLK 152
Cdd:PRK14791  83 LYKISLSLIISGAIGNLIDRIRYGYVVDFIDFHFKDYYFPVFNVADILVVVGTILLAIYILK 144
lspA TIGR00077
lipoprotein signal peptidase; Alternate name: lipoprotein signal peptidase [Protein fate, ...
 12-160 1.75e-26

lipoprotein signal peptidase; Alternate name: lipoprotein signal peptidase [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 272893 [Multi-domain]  Cd Length: 166  Bit Score: 98.20  E-value: 1.75e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446471354   12 LIAVFVVIFDQVTKYIIATTMKIGDSFEV-IPHFLNITSHRNNGAAWGILS---GKMTFFFIITIIILIALVYFFIKDAQ 87
Cdd:TIGR00077  14 LVAILFIGFDQLSKYLVLQNFDLGETYFVaFSGVFNITYVRNTGAAFSLLAdqgGQVYFLKGLAIAISLGLFVFLLRYKE 93

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446471354   88 YNLFMQVAISLLFAGALGNFIDRVLTGEVVDFIDTNIFGYDFPIFNIADSSLTIGVILIIIALLKDTSNKKEK 160
Cdd:TIGR00077  94 LFKITNIAFGLIFGGALGNFIDRLVRGGVVDFFDFYFGNYHFPIFNFADSSICIGVILLLLYFFFPKRKKKKD 166
PRK14767 PRK14767
lipoprotein signal peptidase; Provisional
 3-151 6.16e-22

lipoprotein signal peptidase; Provisional


Pssm-ID: 237811  Cd Length: 174  Bit Score: 86.68  E-value: 6.16e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446471354   3 KKYFIGTSILIAVFVVIFDQVTKYIIATTMKIGDSFEVIPHFLNITSHRNNGAAWGILSGKMTFFFIITIIILIALVYFF 82
Cdd:PRK14767   6 KKKSLIKYGILFVILVILDQITKYLAVSHLADKPSFVIIPGVFELIYLENSGAAFGMLSGKAVFFLVITVAVVIIMAFVF 85

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446471354  83 IK---DAQYNLFMQVAIsLLFAGALGNFIDRVLTGEVVDFIDTNIFgyDFPIFNIADSSLTIGVILIIIALL 151
Cdd:PRK14767  86 FKlpaTKKYNPLHIILV-FIVAGAAGNLIDRILNGYVVDFIYFKLI--NFPIFNVADIYVTVSTFLFIILFL 154
PRK14773 PRK14773
lipoprotein signal peptidase; Provisional
 11-160 4.28e-20

lipoprotein signal peptidase; Provisional


Pssm-ID: 173234  Cd Length: 192  Bit Score: 82.20  E-value: 4.28e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446471354  11 ILIAVF--VVIFDQVTKYIIATTMKI---------------------------GDSFEVIPHFLNITSHRNNGAAWGILS 61
Cdd:PRK14773   7 LLALLFvaLLAADQWTKYLAVERLTTvferggdetlaervagfyteqhleplsTEPYYVWRPVWRMNYVENPGAAWGLFR 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446471354  62 G-----KMTFFFIITIIILIALVYFFIKDAQYNLFMQVAISLLFAGALGNFIDRVLTGEVVDFIDTNIF---GYDFPIFN 133
Cdd:PRK14773  87 GhseefRNAFFTLVSLAAVAFILHYYRKLRQEQRYLQVALALVLGGAVGNFVDRLARGYVIDFIEWYWWnrpDIRWPTFN 166

                        170       180
                 ....*....|....*....|....*..
gi 446471354 134 IADSSLTIGVILIIIallkDTSNKKEK 160
Cdd:PRK14773 167 VADSLIVVGVAMLVL----HPGSRKEA 189
PRK14787 PRK14787
lipoprotein signal peptidase; Provisional
 12-148 6.88e-20

lipoprotein signal peptidase; Provisional


Pssm-ID: 173248  Cd Length: 159  Bit Score: 80.82  E-value: 6.88e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446471354  12 LIAVFVVIFDQVTKYIIATTMKIG-DSFEVIPHFLNITSHRNNGAAWGILSGKMTFFFIITIIILIALVYFFIKDAQYNL 90
Cdd:PRK14787   6 LLALAVIVLDQFTKKLAITFLRDGpQSITIIPDWFKLTYAENRGIAFGLEFAPPEVLLLLTGAISAGVLWYVLRSKNRTP 85

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446471354  91 FMQVAISLLFAGALGNFIDRVLTGEVVDFIDTNIF-GYDF-------PIFNIADSSLTIGVILIII 148
Cdd:PRK14787  86 LFLLAFGLILGGGIGNLIDRITSGRVVDFIYFDLYqGYIFgiwvslwPIFNIADSAITIGACMLLL 151
PRK14771 PRK14771
lipoprotein signal peptidase; Provisional
 12-151 1.08e-19

lipoprotein signal peptidase; Provisional


Pssm-ID: 184816  Cd Length: 165  Bit Score: 80.63  E-value: 1.08e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446471354  12 LIAVFVVIFDQVTKYIIATTMKIGDSFEVIPHFLNITSHRNNGAAWGILSGKMTFFFIITIIILIALVYFFIKDAqyNLF 91
Cdd:PRK14771  17 CIAIAALIVDQLTKAWAQAALSDGQTIRVIPGLLSLTLVRNPGASLGMGSGATWVISLLAIVACVALVVAAVRTI--SMK 94

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446471354  92 MQVAISLLFAGALGNFIDRV------LTGEVVDFIDtnifgYDFPIFNIADSSLTIGVILIIIALL 151
Cdd:PRK14771  95 WTVALALAFAGALGNLIDRVmyaqgfLNGKVVDFLN-----YGWSVGNVADIFLMIAGIALVILIL 155
PRK14785 PRK14785
lipoprotein signal peptidase; Provisional
 12-151 1.54e-19

lipoprotein signal peptidase; Provisional


Pssm-ID: 184820  Cd Length: 171  Bit Score: 80.25  E-value: 1.54e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446471354  12 LIAVFVVIFDQVTKYIIATTMKIGDSFEVIPHFLNITSHRNNGAAWGILSG----KMTFFFIITIIILIALVYFFIKDAQ 87
Cdd:PRK14785  19 LLSLVVLILDQWTKWLAETKLTFLEPVPVIEPFLNWTLAYNYGAAFSFLADaggwQKWFFAGLALIMSLFLIVYLKKAPR 98

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446471354  88 YNLFMQVAISLLFAGALGNFIDRVLTGEVVDFIDTNIFG-YDFPIFNIADSSLTIGVILIIIALL 151
Cdd:PRK14785  99 QAKLLSLGLALVLGGAIGNLIDRLLHGHVIDFIHVHYADvWHYPIFNIADIGICVGVALIVIDML 163
PRK14790 PRK14790
lipoprotein signal peptidase; Provisional
 9-153 1.33e-17

lipoprotein signal peptidase; Provisional


Pssm-ID: 173251  Cd Length: 169  Bit Score: 75.28  E-value: 1.33e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446471354   9 TSILIAVFVVIFDQVTKYIIATTMKIGDSFEVIP---HFLNITSHRNNGAAWGILSGKMTFFFIITIIILIALVYFFIKD 85
Cdd:PRK14790  11 TPALVAATILALDQASKRWILATLGPVPMTKFIPligEDIRLAYSHNTGIAFSLFDGKSDILTVVALVISLGAIYLYRTQ 90

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446471354  86 -AQYNLFMQVAISLLFAGALGNFIDRVLTGEVVDFIDTNIfgydFPIFNIADSSLTIGVILIIIALLKD 153
Cdd:PRK14790  91 lPNRRLLIQVAMGLILGGALGNVIDRIRLGYVVDFIQVGW----FPIFNLADSAITVGAALLMLQYALD 155
PRK14777 PRK14777
lipoprotein signal peptidase; Provisional
 11-149 1.85e-17

lipoprotein signal peptidase; Provisional


Pssm-ID: 237814 [Multi-domain]  Cd Length: 184  Bit Score: 75.27  E-value: 1.85e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446471354  11 ILIAVFVVIFDQVTK-YIIATTMKIGDSFEVIPHFLNITSHRNNGAAWGILSGKMTFFFIITIIILIALVYFFIKDAQyN 89
Cdd:PRK14777  30 LVLATLLIVLDQALKaWALANLQLGAPAIPVLPGVLDWVLTFNTGAAWSLFSGSALPLALMRLLVGLGLLVYLLRRPQ-P 108

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446471354  90 LFMQVAISLLFAGALGNFIDRVLTGEVVDFIDT--------NIFGYDFPIFNIADSSLTIGVILIIIA 149
Cdd:PRK14777 109 RFLTVVLSLIAAGAIGNAIDGLRFGRVTDMLHSpalsavtrALGQGDFPIFNLADMCVVGGTLLLLFA 176
PRK14786 PRK14786
lipoprotein signal peptidase; Provisional
 5-161 6.80e-17

lipoprotein signal peptidase; Provisional


Pssm-ID: 173247  Cd Length: 154  Bit Score: 73.09  E-value: 6.80e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446471354   5 YFIGTSILIAVfvvifDQVTKYIIATTMKIGDSFEVIPHFLNITSHRNNGAAWGILSGKMTFFFIITIIILIALVYFFIK 84
Cdd:PRK14786   3 YIFIITILTGI-----DQWTKYLIETQLKPIGAIPIVKDIFHLTYARNTGAAFSILRDKQAFLILVTTIVVGALIYYLIK 77

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446471354  85 DAQ-YNLFMQVAISLLFAGALGNFIDRVLTGEVVDFIDTNIFGYdfPIFNIADSSLTIGVILIIIALLKDTSNKKEKE 161
Cdd:PRK14786  78 ILKtGEVAFKLSLAIIIGGALGNLIDRVRLNYVTDFLDFTLINY--PIFNLADVFVVSGVVMLSYMLLFKGDMPKISK 153
PRK14784 PRK14784
lipoprotein signal peptidase; Provisional
 18-155 1.38e-16

lipoprotein signal peptidase; Provisional


Pssm-ID: 184819 [Multi-domain]  Cd Length: 160  Bit Score: 72.19  E-value: 1.38e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446471354  18 VIFDQVTKYIIATTMKIGDSfevIPH--FLNITSHRNNGAAWGILSGKM-TFFFIITIIILIALVYFFIKDAQYNLFMQ- 93
Cdd:PRK14784  15 ILADQLSKFIITANLTTGTS---IPEsgFFQIVHVHNTGAAFSIFRGHIeWLIAASVLGVILAMTAFFIRKKLPFLDTRp 91

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446471354  94 --VAISLLFAGALGNFIDRVLTGEVVDFIDTNifgyDFPIFNIADSSLTIGVILIIIALLKDTS 155
Cdd:PRK14784  92 glIALGVILAGTVGNLIDRVRLGYVTDFIRVG----DFPTFNIADSCLTVGVIGLLLLYLVSSH 151
PRK14772 PRK14772
lipoprotein signal peptidase; Provisional
 14-155 5.86e-16

lipoprotein signal peptidase; Provisional


Pssm-ID: 237812 [Multi-domain]  Cd Length: 190  Bit Score: 71.44  E-value: 5.86e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446471354  14 AVFVVIFDQVTKYIIATTMKIGDSFEVIPHFLNITSHRNNGAAWGIlsGKMTFFFIITIIILIALVYFFIKDAQYNLFMQ 93
Cdd:PRK14772  32 AVFAYVFDQLTKLWVTSTMVEGERIPVLPPLLHWYYIRNSGAAFSI--GENVTWVFSIIMAAVAVAILVQLRKLGSAWWA 109

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446471354  94 VAISLLFAGALGNFIDRVL------TGEVVDFIDTNifgyDFPIFNIADSSLTIGVILIIIALLKDTS 155
Cdd:PRK14772 110 LALGLLLGGALGNLTDRLFrepsfgMGHVVDFIQLP----NFAIFNIADSAVVSGVVIICLLTLRGVS 173
PRK14770 PRK14770
lipoprotein signal peptidase; Provisional
 12-148 9.48e-16

lipoprotein signal peptidase; Provisional


Pssm-ID: 173231  Cd Length: 167  Bit Score: 70.23  E-value: 9.48e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446471354  12 LIAVFVVIFDQVTKYIIATTMKIGD--SFEVIPhFLNITSHRNNGAAWGILSGKMTFFFIITIIILIALVYFFIKDAQYN 89
Cdd:PRK14770  15 ALLVAVLLLDQASKYWILYGLDLPDrgSVPVLP-FLNFTMVWNHAVTFGMLGGLGGIGRVVFSAVSLAAVLLLGVWLTRT 93

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446471354  90 LFMQVAISL--LFAGALGNFIDRVLTGEVVDFIDTNIFGYDFPIFNIADSSLTIGVILIII 148
Cdd:PRK14770  94 PRPLVAAALgaIMGGAIGNVIDRMRYGAVVDFLHAHAFGWSWYVFNLADAAIDCGVAVLLI 154
PRK14789 PRK14789
lipoprotein signal peptidase; Provisional
 1-143 3.86e-15

lipoprotein signal peptidase; Provisional


Pssm-ID: 173250  Cd Length: 191  Bit Score: 69.29  E-value: 3.86e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446471354   1 MHKKYFIgtSILIAVFVVIFDQVTKYIIATTM-KIGDSFEVIPHFLNITSHRNNGAAWGIL--SGKMTFFFIITIIILIA 77
Cdd:PRK14789   1 LRSRWML--LVLVAIPVFVIDQLSKVWLSDVLlRYNRPIPLLFDWVQLAYHENTGVAFGLFpdQGGVLSVGAGLVLLLLA 78

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446471354  78 LVYFFIKDAQyNLFMQVAISLLFAGALGNFIDRVLTGEVVDFIDtniFGYdFPIFNIADSSLTIGV 143
Cdd:PRK14789  79 LTYQYILPAD-SRWITVAVGMIFGGGLSNLVDRIRQGYVVDFIQ---FGW-WPVFNLADSAITIGV 139
PRK14779 PRK14779
lipoprotein signal peptidase; Provisional
 11-147 2.11e-14

lipoprotein signal peptidase; Provisional


Pssm-ID: 184818  Cd Length: 159  Bit Score: 66.65  E-value: 2.11e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446471354  11 ILIAVFVVIFDQVTKYIiATTMKIGDSFEVIPhFLNITSHRNNGAAWGILSG------KMTFFFIITIIILIALVYFFIK 84
Cdd:PRK14779   9 LGTFFLVLVLDLITKYL-AEKYLFDKDISVIP-FLDLVLVYNKGVAFGLLSEapdfirLPILLLTPIIALIITFLYALKS 86

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446471354  85 DAQYNLFmqvAISLLFAGALGNFIDRVLTGEVVDFIDTNIFGYDFPIFNIADSSLTIGVILII 147
Cdd:PRK14779  87 NDKLSNL---SMGLIGGGALGNLYDRFFLGQVRDFIDIYIGDFHWPAFNIADASISIGIALFI 146
PRK14776 PRK14776
lipoprotein signal peptidase; Provisional
 21-147 1.60e-12

lipoprotein signal peptidase; Provisional


Pssm-ID: 173237  Cd Length: 170  Bit Score: 61.87  E-value: 1.60e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446471354  21 DQVTKYIIATTMKIGDSFEVIPhFLNITSHRNNGAAWGILSGKMTFFFIITIIILIALVYFFIKDAQYNLFMQVAI--SL 98
Cdd:PRK14776  24 DQAVKWLVQQSMAYGEYVSVTP-FFNWVHLWNTGAAFSLFANGGGWQRYFFIGIAVVVSIFLIKLILENRHKGEAIaySL 102

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*....
gi 446471354  99 LFAGALGNFIDRVLTGEVVDFIDTNIFGYDFPIFNIADSSLTIGVILII 147
Cdd:PRK14776 103 ILGGAMGNLIDRVFRGYVVDSFDFYWRDWHWPAFNLADIAIVLGALLFV 151
PRK14788 PRK14788
lipoprotein signal peptidase; Provisional
 10-148 2.76e-12

lipoprotein signal peptidase; Provisional


Pssm-ID: 237816  Cd Length: 200  Bit Score: 61.52  E-value: 2.76e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446471354  10 SILIAVFVVIFDQVTKYIIATTMKIGDSFEVIPhFLNITSHRNNGAAWGI----LSGKMTFFFIITIIILiALVYFFIKD 85
Cdd:PRK14788   4 AFLIILLVLLIDQISKIYVKTHFVLGQSVLVFD-WFKIHFVENPGMAFGMelggEYGKLFLTLFRIVAVG-GIGYYLWKL 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446471354  86 A--QYNLFMQVAISLLFAGALGNFIDRVL---------------------------TGEVVD-----FIDTNI------- 124
Cdd:PRK14788  82 VkkNSSKGLIICISLILAGAIGNIIDSVFygvifdngsygqiatffpegggystwfHGKVVDmfyfpIIDGYLpewvpfw 161

                        170       180
                 ....*....|....*....|....*...
gi 446471354 125 ----FGYDFPIFNIADSSLTIGVILIII 148
Cdd:PRK14788 162 ggehFVFFKPVFNIADSAISIGVILLLL 189
PRK14774 PRK14774
lipoprotein signal peptidase; Provisional
 12-160 5.73e-10

lipoprotein signal peptidase; Provisional


Pssm-ID: 173235  Cd Length: 185  Bit Score: 55.41  E-value: 5.73e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446471354  12 LIAVFVVIFDQVTKYIIATTMKIGD--SFEVIPHFLNITSHRNNGAAWGILSGKMTFF---FIITIIILIALVYFFIKDA 86
Cdd:PRK14774   6 LTAFGVFVLDQLTKWLVVWGLDLANrgAIDLVAPWLTFRMAWNRGINFGIGSSDQEIVrwgLVIVSLAISAWVWRWVWRS 85

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446471354  87 QYNLFMQVAISLLFAGALGNFIDRVLTGEVVDFIDTNIFGYDFP-IFNIADSSLTIGVILIIIaLLKDTSNKKEK 160
Cdd:PRK14774  86 TPTRLARISGGLLIGGALGNVVDRVLYGAVADFLNMSCCGIENPyAFNVADIAIFAGAFGLVL-FTRETKPEPEK 159
PRK14778 PRK14778
lipoprotein signal peptidase; Provisional
 15-158 6.68e-09

lipoprotein signal peptidase; Provisional


Pssm-ID: 173239  Cd Length: 186  Bit Score: 52.51  E-value: 6.68e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446471354  15 VFVVIFDQVTKYIIAttmKIGDSFEVIPHFLNITSHRNNGAAWGI---LSGKMTFFFIITIIILIALVYFFikdaQYNLF 91
Cdd:PRK14778   6 VLTIVLDQLTKRIAS---EIHGTFFIVPGFLRFVKATNRGVALGLfsnLSEQVLWTVLFVVVFLSLLPYIF----RFSRL 78

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446471354  92 MQVAISLLFAGALGNFIDRVLTGEVVDFIDtniFGYDFPIFNIADSSLTIGVILIIIALLKDTSNKK 158
Cdd:PRK14778  79 ERMAMGFILGGALGNLLDRIRFGYVLDFLN---LTFLPTIFNLADVFIIVGGALMILGVFRGGDNES 142
PRK14775 PRK14775
lipoprotein signal peptidase; Provisional
 3-144 7.29e-08

lipoprotein signal peptidase; Provisional


Pssm-ID: 237813  Cd Length: 170  Bit Score: 49.12  E-value: 7.29e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446471354   3 KKYFIGtsILIAVFVVIFDQVTK-YIIATTMKIGDSfeVIPHFLNITSHRNNGAAWGI---LSGKMTFFFIITIIILIAL 78
Cdd:PRK14775   2 KSKIVG--VIAIVLVFALDQVSKaYAIDWYSQSGAT--EVFKFCSLVEVWNRGISFGMfgaLESSNLIFTYVSLGVILML 77

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446471354  79 VYFFIKDAQYNlfMQVAISLLFAGALGNFIDRVLTGEVVDFIDTNIFGYDFPIFNIADSSLTIGVI 144
Cdd:PRK14775  78 FVLFVQSKCNK--STICMGVVIGGALGNLADRLRFGAVYDFISLHAGEFHWPAFNFADVCVTCGVI 141
PRK14766 PRK14766
lipoprotein signal peptidase; Provisional
 13-148 3.11e-07

lipoprotein signal peptidase; Provisional


Pssm-ID: 173227  Cd Length: 201  Bit Score: 47.94  E-value: 3.11e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446471354  13 IAVFVVIFDQVTKYIIATTMKIGDSFEVIPHFLNITSHRNNGAAWGILSGKMTFFFIITIIILIAL--VYFFIKDAQYnl 90
Cdd:PRK14766  30 IFISLISFDWIIKAVVVSHMKLGETKTFISGFLNFQYVINLGMAYGRLADKLYLVIIFATIFSLFLtiVFIFLNNKKW-- 107

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446471354  91 fmQVAISLLFAGALGNFIDRV--------LTGEVVDFI--DTNIFGYDFPIFNIADSSLTIGVILIII 148
Cdd:PRK14766 108 --LIVLSILLAGSWGNLLARLwapgneqnIYGGVVDFLtwDFSLLNSRDYVFNLADLYVNIAIGLTIL 173
PRK14781 PRK14781
lipoprotein signal peptidase; Provisional
 98-152 3.17e-07

lipoprotein signal peptidase; Provisional


Pssm-ID: 237815  Cd Length: 153  Bit Score: 47.11  E-value: 3.17e-07
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 446471354  98 LLFAGALGNFIDRVLTGEVVDFIDTnifGYdFPIFNIADSSLTIGVILIIIALLK 152
Cdd:PRK14781  94 LLLGGAVGNFIDRLDGRGVVDYLHS---GW-FPTFNLADVFVTTGVALLVLGMLR 144
PRK14768 PRK14768
lipoprotein signal peptidase; Provisional
 11-151 3.25e-07

lipoprotein signal peptidase; Provisional


Pssm-ID: 173229  Cd Length: 148  Bit Score: 47.21  E-value: 3.25e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446471354  11 ILIAVFVVIFDQVTKYIIATTMKIGDSFEVIPHFLNITSHRNNGAAWGILSGKMTFFFIITIIILIALVYFfIKDAQYNL 90
Cdd:PRK14768   4 ILIIILLIGLDQLSKIWVLNNLVDVSTIPIINNVFHLTYVENRGAAFGLLQNNQWIFIIVALLATVFGLYY-LNTRKVHI 82

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446471354  91 FMQVAISLLFAGALGNFIDRVLTGEVVDFIDTNIFgYDFpIFNIADSSLTIGVILIIIALL 151
Cdd:PRK14768  83 FGRLGIILIISGALGNLIDRVRLGFVVDYFDFRVI-WEY-VFNVADVFVVVGTVFLCIYVL 141
PRK14783 PRK14783
lipoprotein signal peptidase; Provisional
 16-150 2.36e-05

lipoprotein signal peptidase; Provisional


Pssm-ID: 173244  Cd Length: 182  Bit Score: 42.55  E-value: 2.36e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446471354  16 FVVIFDQVTKYIIATTMKIGDSFEVIPHFLNITSHRNNGAAWGILSGKMTFFFIITIIILIALVYFFIKDaqYNLFMQVA 95
Cdd:PRK14783  22 LGIFLDLVTKFLVILYFYPHRYLEVLGSFFRMTLTFNTGFVFGAFQDNAIPSLIATGFAIVFLIGYRWKN--SDLGNPWG 99

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446471354  96 ISLLFAGALGNFIDRVLT---------------GE---VVDFIDTN----IFGYDFPIFNIADSSLTIGVILIIIAL 150
Cdd:PRK14783 100 WNLVMAGAFGNFLDKFFVkipgtgfrfgfqpnkGEyigVVDFLDFDwpdfLLFSRWPAFNVADSCVTIGLTILIFTM 176
PRK14769 PRK14769
lipoprotein signal peptidase; Provisional
 94-149 5.61e-05

lipoprotein signal peptidase; Provisional


Pssm-ID: 173230  Cd Length: 156  Bit Score: 41.06  E-value: 5.61e-05
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 446471354  94 VAISLLFAGALGNFIDRVLTGEVVDFIDTnifGYdFPIFNIADSSLTIGVILIIIA 149
Cdd:PRK14769  91 IAGGAVIGGALANVVDRARDGLVTDYLHT---GW-WPTFNLADTFLVTGFAVIALL 142
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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