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Conserved domains on  [gi|446443675|ref|WP_000521530|]
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oligopeptide ABC transporter permease [Staphylococcus aureus]

Protein Classification

ABC transporter permease( domain architecture ID 11427312)

ABC transporter permease similar to ABC oligopeptide transporter permease proteins (OppB, AppB, and AmiC), the transmembrane subunits (TM) found in periplasmic binding protein (PBP)-dependent ATP-binding cassette (ABC) transporters which generally bind type 2 PBPs

Gene Ontology:  GO:0055085
PubMed:  18535149|17723295
TCDB:  3.A.1

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DppB COG0601
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 1-304 5.47e-126

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


:

Pssm-ID: 440366 [Multi-domain]  Cd Length: 314  Bit Score: 362.08  E-value: 5.47e-126
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446443675   1 MGKYIFKRFIYMLISLFIIITITFFLMKLIPGSPFN---DAKLNAEQKEILNEKYGLNDPVATQYLHYLKNVVTGDFGNS 77
Cdd:COG0601    1 MLRYILRRLLQAIPVLLGVSTLVFLLLRLLPGDPAAallGPRATPEAIAALRAELGLDQPLLVQYLDWLGGLLRGDLGTS 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446443675  78 FQYhNQPVWDLIKPRLLPSFEMGLTAMFIGVILGLILGVAAATKQNSWVDYTTTVISVIAVSVPSFVLAVLLQYVFAVKL 157
Cdd:COG0601   81 FVY-GRPVSDLIAERLPVTLELALLALLLALLIGIPLGILAALRRGSWLDRLITVLALLGISIPSFWLGLLLILLFAVKL 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446443675 158 RWFPVAGW--------EGFSTAVLPSLALSAAVLATVARYIRAEMIEVLSSDYILLARAKGNSTMRVLFGHALRNALIPI 229
Cdd:COG0601  160 GWLPVSGRvspwedflDALRHLILPALTLALGSLAGIARLTRSSMLEVLGQDYVRTARAKGLSERRVLLRHALRNALIPV 239

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446443675 230 ITIIVPMLASILTGTLTIENIFGVPGLGDQFVRSITTNDFSVIMAITLLFSTLFIVSIFIVDILYGVIDPRIRVQ 304
Cdd:COG0601  240 VTVLGLQLGGLLGGAVVVETVFSWPGLGRLLVDAILNRDYPVVQGIVLLIAVLVVLVNLLVDLLYALLDPRIRLG 314
 
Name Accession Description Interval E-value
DppB COG0601
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 1-304 5.47e-126

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440366 [Multi-domain]  Cd Length: 314  Bit Score: 362.08  E-value: 5.47e-126
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446443675   1 MGKYIFKRFIYMLISLFIIITITFFLMKLIPGSPFN---DAKLNAEQKEILNEKYGLNDPVATQYLHYLKNVVTGDFGNS 77
Cdd:COG0601    1 MLRYILRRLLQAIPVLLGVSTLVFLLLRLLPGDPAAallGPRATPEAIAALRAELGLDQPLLVQYLDWLGGLLRGDLGTS 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446443675  78 FQYhNQPVWDLIKPRLLPSFEMGLTAMFIGVILGLILGVAAATKQNSWVDYTTTVISVIAVSVPSFVLAVLLQYVFAVKL 157
Cdd:COG0601   81 FVY-GRPVSDLIAERLPVTLELALLALLLALLIGIPLGILAALRRGSWLDRLITVLALLGISIPSFWLGLLLILLFAVKL 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446443675 158 RWFPVAGW--------EGFSTAVLPSLALSAAVLATVARYIRAEMIEVLSSDYILLARAKGNSTMRVLFGHALRNALIPI 229
Cdd:COG0601  160 GWLPVSGRvspwedflDALRHLILPALTLALGSLAGIARLTRSSMLEVLGQDYVRTARAKGLSERRVLLRHALRNALIPV 239

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446443675 230 ITIIVPMLASILTGTLTIENIFGVPGLGDQFVRSITTNDFSVIMAITLLFSTLFIVSIFIVDILYGVIDPRIRVQ 304
Cdd:COG0601  240 VTVLGLQLGGLLGGAVVVETVFSWPGLGRLLVDAILNRDYPVVQGIVLLIAVLVVLVNLLVDLLYALLDPRIRLG 314
oppB PRK09471
oligopeptide ABC transporter permease OppB;
1-302 7.84e-93

oligopeptide ABC transporter permease OppB;


Pssm-ID: 181886 [Multi-domain]  Cd Length: 306  Bit Score: 277.72  E-value: 7.84e-93
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446443675   1 MGKYIFKRFIYMLISLFIIITITFFLMKLIPGSPFN-DAKLNAEQKEILNEKYGLNDPVATQYLHYLKNVVTGDFGNSFQ 79
Cdd:PRK09471   1 MLKFILRRCLEAIPTLFILITISFFMMRLAPGSPFTgERTLPPEVMANIEAKYHLNDPIMTQYFSYLKQLAHGDFGPSFK 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446443675  80 YHNQPVWDLIKPRLLPSFEMGLTAMFIGVILGLILGVAAATKQNSWVDYTTTVISVIAVSVPSFVLAVLLQYVFAVKLRW 159
Cdd:PRK09471  81 YKDYSVNDLVASSFPVSAKLGAAAFFLAVILGVSAGVIAALKQNTKWDYTVMGFAMTGVVIPSFVVAPLLVLIFAITLHW 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446443675 160 FPVAGWEG--FSTAVLPSLALSAAVLATVARYIRAEMIEVLSSDYILLARAKGNSTMRVLFGHALRNALIPIITIIVPML 237
Cdd:PRK09471 161 LPGGGWNGgaLKFMILPMVALSLAYIASIARITRGSMIEVLHSNFIRTARAKGLPMRRIILRHALKPALLPVLSYMGPAF 240

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446443675 238 ASILTGTLTIENIFGVPGLGDQFVRSITTNDFSVIMAITLLFSTLFIVSIFIVDILYGVIDPRIR 302
Cdd:PRK09471 241 VGIITGSMVIETIFGLPGIGQLFVNGALNRDYSLVLSLTILVGALTILFNAIVDVLYAVIDPKIR 305
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 111-303 3.74e-26

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 101.99  E-value: 3.74e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446443675  111 GLILGVAAATKQNSWVDYTTTVISVIAVSVPSFVLAVLLQYVFavklrwfpvaGWEGFSTAVLPSLALSAAVLATVARYI 190
Cdd:pfam00528   1 GIPLGIIAALRRGRRLDRLLRPLIDLLQALPSFVLAILLVVIA----------ILSILGHGILPAIILALLGWAGYARLI 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446443675  191 RAEMIEVLSSDYILLARAKGNSTMRVLFGHALRNALIPIITIIVPMLASILTGTLTIENIFGVPGLGDQFVRSITTNDFS 270
Cdd:pfam00528  71 RRAALRSLPSDLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSWPGLGLLLIEAILGYDYP 150

                         170       180       190
                  ....*....|....*....|....*....|...
gi 446443675  271 VIMAITLLFSTLFIVSIFIVDILYGVIDPRIRV 303
Cdd:pfam00528 151 EIQGPVLAAALILLLLNLLVDILQRLLDPRVRK 183
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 93-285 3.58e-17

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 78.09  E-value: 3.58e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446443675  93 LLPSFEMGLTAMFIGVILGLILGVAAATKqNSWVDYTTTVISVIAVSVPSFVLAVLLQYVFAVKLRWFPVAGWegfstaV 172
Cdd:cd06261    1 LLNTLLLALIATLLALVLGLLLGIILARK-RGKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLGWGILPGL------G 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446443675 173 LPSLALSAAVLATVARYIRAEMIEVLSSDYILLARAKGNSTMRVLFGHALRNALIPIITIIVPMLASILTGTLTIENIFG 252
Cdd:cd06261   74 LPALILALLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGG 153

                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 446443675 253 ----VPGLGDQFVRSITTNDFSVIMAITLLFSTLFIV 285
Cdd:cd06261  154 geapGPGTGLLLIFAILFPGDLGVAAAVALILLLLSL 190
 
Name Accession Description Interval E-value
DppB COG0601
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 1-304 5.47e-126

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440366 [Multi-domain]  Cd Length: 314  Bit Score: 362.08  E-value: 5.47e-126
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446443675   1 MGKYIFKRFIYMLISLFIIITITFFLMKLIPGSPFN---DAKLNAEQKEILNEKYGLNDPVATQYLHYLKNVVTGDFGNS 77
Cdd:COG0601    1 MLRYILRRLLQAIPVLLGVSTLVFLLLRLLPGDPAAallGPRATPEAIAALRAELGLDQPLLVQYLDWLGGLLRGDLGTS 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446443675  78 FQYhNQPVWDLIKPRLLPSFEMGLTAMFIGVILGLILGVAAATKQNSWVDYTTTVISVIAVSVPSFVLAVLLQYVFAVKL 157
Cdd:COG0601   81 FVY-GRPVSDLIAERLPVTLELALLALLLALLIGIPLGILAALRRGSWLDRLITVLALLGISIPSFWLGLLLILLFAVKL 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446443675 158 RWFPVAGW--------EGFSTAVLPSLALSAAVLATVARYIRAEMIEVLSSDYILLARAKGNSTMRVLFGHALRNALIPI 229
Cdd:COG0601  160 GWLPVSGRvspwedflDALRHLILPALTLALGSLAGIARLTRSSMLEVLGQDYVRTARAKGLSERRVLLRHALRNALIPV 239

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446443675 230 ITIIVPMLASILTGTLTIENIFGVPGLGDQFVRSITTNDFSVIMAITLLFSTLFIVSIFIVDILYGVIDPRIRVQ 304
Cdd:COG0601  240 VTVLGLQLGGLLGGAVVVETVFSWPGLGRLLVDAILNRDYPVVQGIVLLIAVLVVLVNLLVDLLYALLDPRIRLG 314
oppB PRK09471
oligopeptide ABC transporter permease OppB;
1-302 7.84e-93

oligopeptide ABC transporter permease OppB;


Pssm-ID: 181886 [Multi-domain]  Cd Length: 306  Bit Score: 277.72  E-value: 7.84e-93
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446443675   1 MGKYIFKRFIYMLISLFIIITITFFLMKLIPGSPFN-DAKLNAEQKEILNEKYGLNDPVATQYLHYLKNVVTGDFGNSFQ 79
Cdd:PRK09471   1 MLKFILRRCLEAIPTLFILITISFFMMRLAPGSPFTgERTLPPEVMANIEAKYHLNDPIMTQYFSYLKQLAHGDFGPSFK 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446443675  80 YHNQPVWDLIKPRLLPSFEMGLTAMFIGVILGLILGVAAATKQNSWVDYTTTVISVIAVSVPSFVLAVLLQYVFAVKLRW 159
Cdd:PRK09471  81 YKDYSVNDLVASSFPVSAKLGAAAFFLAVILGVSAGVIAALKQNTKWDYTVMGFAMTGVVIPSFVVAPLLVLIFAITLHW 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446443675 160 FPVAGWEG--FSTAVLPSLALSAAVLATVARYIRAEMIEVLSSDYILLARAKGNSTMRVLFGHALRNALIPIITIIVPML 237
Cdd:PRK09471 161 LPGGGWNGgaLKFMILPMVALSLAYIASIARITRGSMIEVLHSNFIRTARAKGLPMRRIILRHALKPALLPVLSYMGPAF 240

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446443675 238 ASILTGTLTIENIFGVPGLGDQFVRSITTNDFSVIMAITLLFSTLFIVSIFIVDILYGVIDPRIR 302
Cdd:PRK09471 241 VGIITGSMVIETIFGLPGIGQLFVNGALNRDYSLVLSLTILVGALTILFNAIVDVLYAVIDPKIR 305
PRK15081 PRK15081
glutathione ABC transporter permease GsiC; Provisional
 1-302 5.16e-70

glutathione ABC transporter permease GsiC; Provisional


Pssm-ID: 185039 [Multi-domain]  Cd Length: 306  Bit Score: 219.59  E-value: 5.16e-70
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446443675   1 MGKYIFKRFIYMLISLFIIITITFFLMKLIPGSPfndAKLNAEQK------EILNEKYGLNDPVATQYLHYLKNVVTGDF 74
Cdd:PRK15081   1 MLNYVIKRLLGLIPTLLIVAVLVFLFVHLLPGDP---ARLAAGPEadaqvvALVRQQLGLDQPLPHQFWHYISNALQGDF 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446443675  75 GNSFQYHnQPVWDLIKPRLLPSFEMGLTAMFIGVILGLILGVAAATKQNSWVDYTTTVISVIAVSVPSFVLAVLLQYVFA 154
Cdd:PRK15081  78 GTSMVSR-RPVSEEIASRFMPTLWLTITSMVWAVIFGMAIGIASAVWRNRWPDRLGMTLAVSGISFPAFALGMLLMQVFS 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446443675 155 VKLRWFPVAGWEGFSTAVLPSLALSAAVLATVARYIRAEMIEVLSSDYILLARAKGNSTMRVLFGHALRNALIPIITIIV 234
Cdd:PRK15081 157 VELGWLPTVGADSWQHYILPSLTLGAAVAAVMARFTRASFVEVLSEDYMRTARAKGVSETWVVLKHGLRNAMIPVVTMMG 236

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446443675 235 PMLASILTGTLTIENIFGVPGLGDQFVRSITTNDFSVIMAITLLFSTLFIVSIFIVDILYGVIDPRIR 302
Cdd:PRK15081 237 LQFGFLLGGSIVVEKVFNWPGLGRLLVDSVEMRDYPVIQAEVLLFSLEFILINLVVDVLYAAINPAIR 304
PRK10352 PRK10352
nickel transporter permease NikB; Provisional
 1-306 2.29e-59

nickel transporter permease NikB; Provisional


Pssm-ID: 182400 [Multi-domain]  Cd Length: 314  Bit Score: 192.22  E-value: 2.29e-59
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446443675   1 MGKYIFKRFIYMLISLFIIITITFFLMKLIPGSPFND----------AKLNAEQKEILnekyGLNDPVATQYLHYLKNVV 70
Cdd:PRK10352   1 MLRYILRRLLLLIPMLLAASVIIFLMLRLGTGDPALDylrlsnlpptPEMLASTRTML----GLDQPLYVQYGTWLWKAL 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446443675  71 TGDFGNSFQYhNQPVWDLIKPRLLPSFEMGLTAMFIGVILGLILGVAAATKQNSWVDYTTTVISVIAVSVPSFVLAVLLQ 150
Cdd:PRK10352  77 HLDFGISFAT-QRPVLDDLLNFLPATLELAGAALVLILLTSVPLGIWAARHRDRLPDFAVRFIAFLGVSMPNFWLAFLLV 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446443675 151 YVFAVKLRWFPVAGWEGFSTAVLPSLALSAAVLATVARYIRAEMIEVLSSDYILLARAKGNSTMRVLFGHALRNALIPII 230
Cdd:PRK10352 156 MAFSVYLQWLPAMGYGGWQHIILPAVSIAFMSLAINARLLRASMLEVAGQRHVTWARLRGLSERQVERRHILRNASLPMI 235

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446443675 231 TIIVPMLASILTGTLTIENIFGVPGLGDQFVRSITTNDFSVIMAITLLFSTLFIVSIFIVDILYGVIDPRIRVQGG 306
Cdd:PRK10352 236 TAVGMHIGELIGGTMIIENIFAWPGVGRYAVSAIFNRDYPVIQCFTLMMVVVFVVCNLIVDLLNAALDPRIRRHEG 311
PRK10914 PRK10914
dipeptide ABC transporter permease DppB;
1-302 2.93e-53

dipeptide ABC transporter permease DppB;


Pssm-ID: 182834 [Multi-domain]  Cd Length: 339  Bit Score: 177.31  E-value: 2.93e-53
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446443675   1 MGKYIFKRfIYMLISLFIIITI-TFFLMKLIPGSPF----NDAKLNAEQKEILNEKYGLNDPVATQYLHYLKNVVTGDFG 75
Cdd:PRK10914   1 MLQFILRR-LGLVIPTFIGITLlTFAFVHMIPGDPVmimaGERGISPERHAQLLAELGLDKPMWQQYLHYIWGVMHGDLG 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446443675  76 NSFQyHNQPVWDLIKPRLLPSFEMGLTAMFIGVILGLILGVAAATKQNSWVDYTTTVISVIAVSVPSFVLAVLLQYVFAV 155
Cdd:PRK10914  80 ISLK-SRIPVWDEFVPRFKATLELGVCAMIFAVAVGIPVGVLAAVKRGSIFDHTAVGLALTGYSMPIFWWGMMLIMLVSV 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446443675 156 KLRWFPVAG------------------------W--EG-FSTAV----LPSLALSAAVLATVARYIRAEMIEVLSSDYIL 204
Cdd:PRK10914 159 HWNLTPVSGrvsdmvflddsnpltgfmlidtaiWgeDGnFIDAVahmiLPAIVLGTIPLAVIVRMTRSSMLEVLGEDYIR 238

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446443675 205 LARAKGNSTMRVLFGHALRNALIPIITIIVPMLASILTGTLTIENIFGVPGLGDQFVRSITTNDFSVIMAITLLFSTLFI 284
Cdd:PRK10914 239 TARAKGLTRMRVIIVHALRNAMLPVVTVIGLQVGTLLAGAILTETIFSWPGLGRWLIDALQRRDYPVVQGGVLLVATMII 318

                        330
                 ....*....|....*...
gi 446443675 285 VSIFIVDILYGVIDPRIR 302
Cdd:PRK10914 319 LVNLLVDLLYGVVNPRIR 336
PRK15133 PRK15133
microcin C ABC transporter permease YejB; Provisional
 1-305 6.72e-29

microcin C ABC transporter permease YejB; Provisional


Pssm-ID: 185087 [Multi-domain]  Cd Length: 364  Bit Score: 113.69  E-value: 6.72e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446443675   1 MGKYIFKRFIYMLISLFIIITITFFLMKLIPGSPFNDAKLNAE------------------------------------- 43
Cdd:PRK15133   1 MGAYLIRRLLLVIPTLWAIITINFFIVQIAPGGPVDQAIAAIEfgqagglpgaggegvrashaqtgvgnisdsnyrggrg 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446443675  44 -QKEILNE---KYGLNDPVATQYLHYLKNVVTGDFGNSFqYHNQPVWDLIKPRLLPSFEMGLTAMFIGVILGLILGVAAA 119
Cdd:PRK15133  81 lDPEVIAEithRYGFDKPLHERYFKMLWDYIRFDFGDSL-FRSASVLTLIKDSLPVSITLGLWSTLIIYLVSIPLGIRKA 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446443675 120 TKQNSWVDYTTTVISVIAVSVPSFVLAVLLQYVFA--VKLRWFPVAG----------WEGFST-----AVLPSLALSAAV 182
Cdd:PRK15133 160 VRNGSRFDVWSSAFIIIGYAIPAFLFAILLIVFFAggSYFDLFPLRGlvsanfdslpWYQKITdylwhITLPVLATVIGG 239

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446443675 183 LATVARYIRAEMIEVLSSDYILLARAKGNSTMRVLFGHALRNALIPIITIIVPMLASI-LTGTLTIENIFGVPGLGDQFV 261
Cdd:PRK15133 240 FAALTMLTKNSFLDEIRKQYVVTARAKGVSEKNILWKHVFRNAMLLVIAGFPATFISMfFTGSLLIEVMFSLNGLGLLGY 319

                        330       340       350       360
                 ....*....|....*....|....*....|....*....|....
gi 446443675 262 RSITTNDFSVIMAITLLFSTLFIVSIFIVDILYGVIDPRIRVQG 305
Cdd:PRK15133 320 EATVSRDYPVMFGTLYIFTLIGLLLNIVSDISYTLVDPRIDFEG 363
PRK15110 PRK15110
peptide ABC transporter permease SapB;
1-299 4.26e-28

peptide ABC transporter permease SapB;


Pssm-ID: 185065 [Multi-domain]  Cd Length: 321  Bit Score: 110.55  E-value: 4.26e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446443675   1 MGKYIFKRFIYMLISLFIIITITFFLMKLIPGSPFNDAKLnaeqkeilnekyglndpvATQYLHYLKNVVTGDFGNSfQY 80
Cdd:PRK15110   1 MIIFTLRRLLLLIVTLFLLTLVGFSLSYFTPHAPLQGASL------------------WDAWVFWFNGLLHWDFGVS-SI 61

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446443675  81 HNQPVWDLIKPRLLPSFEMGLTAMFIGVILGLILGVAAATKQNSWVDYTTTVISVIAVSVPSFVLAVLLQYVFAVKLRWF 160
Cdd:PRK15110  62 NGQPISEQLKEVFPATMELCILAFGFALLVGIPVGIIAGVTRHKWQDNLISALALLGFSIPVFWLALLLTLFFSLTLGWL 141

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446443675 161 PVAGW----------EGFSTA---------------------VLPSLALSAAVLATVARYIRAEMIEVLSSDYILLARAK 209
Cdd:PRK15110 142 PVSGRfdllyevkpvTGFALIdawlsdspwrdemimsairhmILPVITLAVAPTTEVIRLMRISTIEVYDQNYVKAAATR 221

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446443675 210 GNSTMRVLFGHALRNALIPIITIIVPMLASILTGTLTIENIFGVPGLGDQFVRSITTNDFSVIMAITLLFSTLFIVSIFI 289
Cdd:PRK15110 222 GLSRFTILRRHVLHNALPPVIPRLGLQFSTMLTLAMITEMVFSWPGLGRWLINAIRQQDYAAISAGVMVVGSLVIIVNVL 301

                        330
                 ....*....|
gi 446443675 290 VDILYGVIDP 299
Cdd:PRK15110 302 SDILGAMANP 311
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 111-303 3.74e-26

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 101.99  E-value: 3.74e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446443675  111 GLILGVAAATKQNSWVDYTTTVISVIAVSVPSFVLAVLLQYVFavklrwfpvaGWEGFSTAVLPSLALSAAVLATVARYI 190
Cdd:pfam00528   1 GIPLGIIAALRRGRRLDRLLRPLIDLLQALPSFVLAILLVVIA----------ILSILGHGILPAIILALLGWAGYARLI 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446443675  191 RAEMIEVLSSDYILLARAKGNSTMRVLFGHALRNALIPIITIIVPMLASILTGTLTIENIFGVPGLGDQFVRSITTNDFS 270
Cdd:pfam00528  71 RRAALRSLPSDLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSWPGLGLLLIEAILGYDYP 150

                         170       180       190
                  ....*....|....*....|....*....|...
gi 446443675  271 VIMAITLLFSTLFIVSIFIVDILYGVIDPRIRV 303
Cdd:pfam00528 151 EIQGPVLAAALILLLLNLLVDILQRLLDPRVRK 183
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 93-285 3.58e-17

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 78.09  E-value: 3.58e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446443675  93 LLPSFEMGLTAMFIGVILGLILGVAAATKqNSWVDYTTTVISVIAVSVPSFVLAVLLQYVFAVKLRWFPVAGWegfstaV 172
Cdd:cd06261    1 LLNTLLLALIATLLALVLGLLLGIILARK-RGKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLGWGILPGL------G 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446443675 173 LPSLALSAAVLATVARYIRAEMIEVLSSDYILLARAKGNSTMRVLFGHALRNALIPIITIIVPMLASILTGTLTIENIFG 252
Cdd:cd06261   74 LPALILALLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGG 153

                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 446443675 253 ----VPGLGDQFVRSITTNDFSVIMAITLLFSTLFIV 285
Cdd:cd06261  154 geapGPGTGLLLIFAILFPGDLGVAAAVALILLLLSL 190
DppC COG1173
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 96-242 5.28e-15

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440786 [Multi-domain]  Cd Length: 275  Bit Score: 73.61  E-value: 5.28e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446443675  96 SFEMGLTAMFIGVILGLILGVAAATKqNSWVDYTTTVISVIAVSVPSFVLAVLLQYVFavklrwfpvagweGFSTAVLpS 175
Cdd:COG1173   81 SLLVGLLAVLIALVIGVLLGLLAGYF-GGWVDAVLMRLVDVLLAFPSLLLAIALVAVL-------------GPGLLNV-I 145

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446443675 176 LALSAAVLATVARYIRAEMIEVLSSDYILLARAKGNSTMRVLFGHALRNALIPIITIIVPMLAS-ILT 242
Cdd:COG1173  146 LALGLTGWPGYARLVRAQVLSLREREYVEAARALGASPLRIIFRHILPNVLPPLIVQATLGIASaILA 213
BPD_transp_1_N pfam19300
Binding-prot-dependent transport system membrane comp, N-term; This is the N-terminal ...
 1-93 7.75e-14

Binding-prot-dependent transport system membrane comp, N-term; This is the N-terminal transmembrane domain of the Binding-protein-dependent transport system inner membrane component.


Pssm-ID: 437132 [Multi-domain]  Cd Length: 114  Bit Score: 66.86  E-value: 7.75e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446443675    1 MGKYIFKRFIYMLISLFIIITITFFLMKLIPGSPfndAKL------NAEQKEILNEKYGLNDPVATQYLHYLKNVVTGD- 73
Cdd:pfam19300   1 MLRFLVRRTLGAVVILLIISAVTFFLFYAIPRDP---ARLacgkncTPETLALIRHNLGLDKPIPVQYWHFLSGIFAGRd 77

                          90       100       110
                  ....*....|....*....|....*....|.
gi 446443675   74 -----------FGNSFQyHNQPVWDLIKPRL 93
Cdd:pfam19300  78 fgavghcpapcLGYSFA-NNEPVWDTIMDRF 107
PRK10913 PRK10913
dipeptide ABC transporter permease DppC;
103-230 1.40e-04

dipeptide ABC transporter permease DppC;


Pssm-ID: 182833 [Multi-domain]  Cd Length: 300  Bit Score: 42.85  E-value: 1.40e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446443675 103 AMFIGVILGLILGVAAATkqnswVDYTTTVISVIAVSVPSFVLAVLLQYVFAvklrwfpvagwegfSTAVLPSLALSAAV 182
Cdd:PRK10913 112 SLVMGVILGLIAGYFGGL-----VDNIIMRVVDIMLALPSLLLALVLVAIFG--------------PSIVNAALALTFVA 172

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*...
gi 446443675 183 LATVARYIRAEMIEVLSSDYILLARAKGNSTMRVLFGHALRNALIPII 230
Cdd:PRK10913 173 LPHYVRLTRAAVLVEVNRDYVTASRVAGAGAMRQMFINILPNCLAPLI 220
PRK15021 PRK15021
microcin C ABC transporter permease; Provisional
 96-299 1.82e-04

microcin C ABC transporter permease; Provisional


Pssm-ID: 184982 [Multi-domain]  Cd Length: 341  Bit Score: 42.66  E-value: 1.82e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446443675  96 SFEMGLTAMFIGVILGLILGVAAA---TKQNSWVDYTTTVISviavSVPSFVLAVLLQYVFAVKLRWF----PVAGWEGF 168
Cdd:PRK15021 143 SVLFGLMLTLCSSVMGVLAGALQGyygGKVDLWGQRFIEVWS----GMPTLFLIILLSSVVQPNFWWLlaitVLFGWMSL 218

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446443675 169 STAVlpslalsaavlatvaryiRAEMIEVLSSDYILLARAKGNSTMRVLFGHALRNALIPIITIIVPMLASILTgTLTIE 248
Cdd:PRK15021 219 VGVV------------------RAEFLRTRNFDYIRAAQALGVSDRSIILRHMLPNAMVATLTFLPFILCSSIT-TLTSL 279

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 446443675 249 NIFGV------PGLGDQFVRSiTTNDFSVIMAITLLFSTLFIVS--IFIVDILYGVIDP 299
Cdd:PRK15021 280 DFLGFglplgsPSLGELLLQG-KNNLQAPWLGITAFLSVAILLSllIFIGEAVRDAFDP 337
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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