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Conserved domains on  [gi|446402200|ref|WP_000480055|]
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MULTISPECIES: iron-enterobactin ABC transporter permease [Salmonella]

Protein Classification

iron-enterobactin ABC transporter permease( domain architecture ID 10793391)

iron-enterobactin ABC transporter permease is part of the binding-protein-dependent transport system for ferric enterobactin

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
PRK10440 PRK10440
iron-enterobactin ABC transporter permease;
1-329 1.75e-172

iron-enterobactin ABC transporter permease;


:

Pssm-ID: 182463  Cd Length: 330  Bit Score: 481.52  E-value: 1.75e-172
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446402200   1 MFLSRRLIVSCLLLAAGCFAIGLWSLQSGAVPLDTGQIIAALLGDAPRNITLVVTEWRLPRVLMALLIGAALGVSGAIFQ 80
Cdd:PRK10440   2 IYVSRRLLITCLLLLAACVAAGLWGLRSGAVTLETSQVFAALMGDAPRSMTMVVTEWRLPRVLMALLIGAALGVSGAIFQ 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446402200  81 SLMRNPLGSPDVMGFNTGAWSGVLVAMVLFGQHLTAIALAAMAGGIVTSLIVWLLAWRNGIETFRLIIIGIGIRAMLVAF 160
Cdd:PRK10440  82 SLMRNPLGSPDVMGFNTGAWSGVLVAMVLFGQDLTAIALAAMAGGIVTSLLVWLLAWRNGIDTFRLIIIGIGVRAMLVAF 161
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446402200 161 NTWLLLQASLETALTAGLWNAGSLNGLTWAKTWPSAPLIIVMLTGAALLVRRMRLLEMGDDSACALGVSVERSRLMLMLV 240
Cdd:PRK10440 162 NTWLLLKASLETALTAGLWNAGSLNGLTWAKTSPSAPIIILMLIAAALLVRRMRLLEMGDDTACALGVSVERSRLLLMLV 241
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446402200 241 AVSLTAAATALAGPISFIALVAPHIARRLSGTARWGLTQSALCGALLLLAADACAQQLFMPYQLPVGVVTVSLGGIYLIV 320
Cdd:PRK10440 242 AVVLTAAATALAGPISFIALVAPHIARRLSGTARWGLTQAALCGALLLLAADLCAQQLFMPYQLPVGVVTVSLGGIYLIV 321

                 ....*....
gi 446402200 321 LLIQESRKK 329
Cdd:PRK10440 322 LLIQESRKK 330
 
Name Accession Description Interval E-value
PRK10440 PRK10440
iron-enterobactin ABC transporter permease;
1-329 1.75e-172

iron-enterobactin ABC transporter permease;


Pssm-ID: 182463  Cd Length: 330  Bit Score: 481.52  E-value: 1.75e-172
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446402200   1 MFLSRRLIVSCLLLAAGCFAIGLWSLQSGAVPLDTGQIIAALLGDAPRNITLVVTEWRLPRVLMALLIGAALGVSGAIFQ 80
Cdd:PRK10440   2 IYVSRRLLITCLLLLAACVAAGLWGLRSGAVTLETSQVFAALMGDAPRSMTMVVTEWRLPRVLMALLIGAALGVSGAIFQ 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446402200  81 SLMRNPLGSPDVMGFNTGAWSGVLVAMVLFGQHLTAIALAAMAGGIVTSLIVWLLAWRNGIETFRLIIIGIGIRAMLVAF 160
Cdd:PRK10440  82 SLMRNPLGSPDVMGFNTGAWSGVLVAMVLFGQDLTAIALAAMAGGIVTSLLVWLLAWRNGIDTFRLIIIGIGVRAMLVAF 161
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446402200 161 NTWLLLQASLETALTAGLWNAGSLNGLTWAKTWPSAPLIIVMLTGAALLVRRMRLLEMGDDSACALGVSVERSRLMLMLV 240
Cdd:PRK10440 162 NTWLLLKASLETALTAGLWNAGSLNGLTWAKTSPSAPIIILMLIAAALLVRRMRLLEMGDDTACALGVSVERSRLLLMLV 241
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446402200 241 AVSLTAAATALAGPISFIALVAPHIARRLSGTARWGLTQSALCGALLLLAADACAQQLFMPYQLPVGVVTVSLGGIYLIV 320
Cdd:PRK10440 242 AVVLTAAATALAGPISFIALVAPHIARRLSGTARWGLTQAALCGALLLLAADLCAQQLFMPYQLPVGVVTVSLGGIYLIV 321

                 ....*....
gi 446402200 321 LLIQESRKK 329
Cdd:PRK10440 322 LLIQESRKK 330
FepG COG4779
ABC-type enterobactin transport system, permease component [Inorganic ion transport and ...
3-328 1.14e-109

ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 443810  Cd Length: 344  Bit Score: 322.84  E-value: 1.14e-109
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446402200   3 LSRRLIVSCLLLAAGCFAIGLWSLQSGAVPLDTGQIIAALLGDAPRNITLVVTEWRLPRVLMALLIGAALGVSGAIFQSL 82
Cdd:COG4779   18 LRRRALLVTLVLLLLLLALAVLALTLGDYPLSPGDVLRALLGEGDPGASFVVLELRLPRALAALLVGAALGLSGAIFQSL 97
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446402200  83 MRNPLGSPDVMGFNTGAWSGVLVAMVLFGQHLTAIALAAMAGGIVTSLIVWLLAWRNGIETFRLIIIGIGIRAMLVAFNT 162
Cdd:COG4779   98 TRNPLASPDIIGITAGASAGAVAAIVVLGGSGLAVALGALAGGLATALLVYLLAWRGGVSGYRLILVGIGVSAMLTAVNS 177
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446402200 163 WLLLQASLETALTAGLWNAGSLNGLTWAKTWPSAPLIIVMLTGAALLVRRMRLLEMGDDSACALGVSVERSRLMLMLVAV 242
Cdd:COG4779  178 YLLTRADLEDAQSAAVWLTGSLNGRTWEDVLPLAVALAVLLPLALALARRLRLLELGDDTAAALGVRVERTRLLLLLVAV 257
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446402200 243 SLTAAATALAGPISFIALVAPHIARRLSGTARWGLTQSALCGALLLLAADACAQQLFMPYQLPVGVVTVSLGGIYLIVLL 322
Cdd:COG4779  258 ALAAVATAAAGPIAFVALAAPQIARRLTRSPGPPLLPSALVGALLLLAADLVAQHLLAPVQLPVGVVTGALGGPYLLWLL 337

                 ....*.
gi 446402200 323 IQESRK 328
Cdd:COG4779  338 IRENRR 343
FecCD pfam01032
FecCD transport family; This is a sub-family of bacterial binding protein-dependent transport ...
20-324 5.30e-60

FecCD transport family; This is a sub-family of bacterial binding protein-dependent transport systems family. This Pfam entry contains the inner components of this multicomponent transport system.


Pssm-ID: 426003  Cd Length: 311  Bit Score: 194.67  E-value: 5.30e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446402200   20 AIGLWSLQSGAVPLDTGQIIAALLGDAPRNITLVVTEWRLPRVLMALLIGAALGVSGAIFQSLMRNPLGSPDVMGFNTGA 99
Cdd:pfam01032   4 LLILLSLFIGAVKISPSDVFSALLGGDDSLAALIVLDLRLPRVLAALLVGAALAVSGALLQTVTRNPLADPSILGISSGA 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446402200  100 WSGVLVAMVLFG-QHLTAIALAAMAGGIVTSLIVWLLA-WRNGIETFRLIIIGIGIRAMLVAFNTWLLLQASLETALTAG 177
Cdd:pfam01032  84 ALGAVLAILLGGsLSLFALPLAAFIGALLAALLVYFLSrGRGGASPLRLILAGIAVSALLSALTSLLLLLLNPEALQSIL 163
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446402200  178 LWNAGSLNGLTWAKTWPSAPLIIVMLTGAALLVRRMRLLEMGDDSACALGVSVERSRLMLMLVAVSLTAAATALAGPISF 257
Cdd:pfam01032 164 FWLMGSLSGANWSDVLILLPLLLIGLILLLLLARKLNLLSLGDDTAKSLGVNVNRVRLLLLLLASLLTAASVAVVGPIGF 243
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446402200  258 IALVAPHIARRLSGTA-RWGLTQSALCGALLLLAADACAQQLFMPYQLPVGVVTVSLGGIYLIVLLIQ 324
Cdd:pfam01032 244 VGLIVPHIARLLVGANhRRLLPLSALLGALLLLLADILARTILSPYELPVGIVTALIGAPFFIYLLLR 311
TM_ABC_iron-siderophores_like cd06550
Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
62-322 4.53e-37

Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of a PBP, two TMs, and two cytoplasmic ABCs, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The TMs are bundles of alpha helices that transverse the cytoplasmic membrane multiple times. The two ABCs bind and hydrolyze ATP and drive the transport reaction. Each TM has a prominent cytoplasmic loop which contacts an ABC and represents a conserved motif. The two TMs form either a homodimer (e.g. in the case of the BtuC subunits of the Escherichia coli BtuCD vitamin B12 transporter), a heterodimer (e.g. the TroC and TroD subunits of the Treponema pallidum general transition metal transporter, TroBCD), or a pseudo-heterodimer (e.g. the FhuB protein of the E. coli ferrichrome transporter, FhuBC). FhuB contains two tandem TMs which associate to form the pseudo-heterodimer. Both FhuB TMs are found in this hierarchy.


Pssm-ID: 119348 [Multi-domain]  Cd Length: 261  Bit Score: 133.45  E-value: 4.53e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446402200  62 VLMALLIGAALGVSGAIFQSLMRNPLGSPDVMGFNTGAWSGVLVAMVLFGQH-LTAIALAAMAGGIVTSLIVWLLAWRNG 140
Cdd:cd06550    1 LLAALLVGAALAVSGAILQSLTRNRLASPSILGISHGALLGVVLALLLGIGLsNYALGAFAFAGALAIALLVLLLASRGG 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446402200 141 IETFRLIIIGIGIRAMLVAFNTWLLLQASlETALTAGLWNAGSLNGLTWAKTWPSAPLIIVMLTGAALLVRRMRLLEMGD 220
Cdd:cd06550   81 LSPSKLILIGIVLSAFFSAGVILISLLSD-DSLQDLNIWLFGSILGVTWEDLLILLIILLLVLLLLLLLSRKLNLLTFDE 159
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446402200 221 DSACALGVSVERSRLMLMLVAVSLTAAATALAGPISFIALVAPHIARRLSGTARWGLTQSALCGALLLLAADACAQQLFM 300
Cdd:cd06550  160 DLAKSLGINVNLLRLLLLLLVALLVVAAVALVGVILFVGLIAPHLARRLFGRSHRYLLPLSALLGAILLLLGDLLSRTLL 239
                        250       260
                 ....*....|....*....|..
gi 446402200 301 PYQLPVGVVTVSLGGIYLIVLL 322
Cdd:cd06550  240 PSELPVGPVTALLGAPYFLYLL 261
F420-0_ABCperm TIGR03869
proposed F420-0 ABC transporter, permease protein; his small clade of ABC-type transporter ...
53-327 1.44e-20

proposed F420-0 ABC transporter, permease protein; his small clade of ABC-type transporter permease protein components is found as a three gene cassette along with a periplasmic substrate-binding protein (TIGR03868) and an ATPase (TIGR03873). The organisms containing this cassette are all Actinobacteria and all contain numerous genes requiring the coenzyme F420. This model was defined based on five such organisms, four of which are lacking all F420 biosynthetic capability save the final side-chain polyglutamate attachment step (via the gene cofE: TIGR01916). In Jonesia denitrificans DSM 20603 and marine actinobacterium PHSC20C1 this cassette is in an apparent operon with the cofE gene and, in PHSC20C1, also with an F420-dependent glucose-6-phosphate dehydrogenase (TIGR03554). Based on these observations we propose that this permease protein is a component of a F420-0 (that is, F420 lacking only the polyglutamate tail) transporter.


Pssm-ID: 163581  Cd Length: 325  Bit Score: 90.30  E-value: 1.44e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446402200   53 VVTEWRLPRVLMALLIGAALGVSGAIFQSLMRNPLGSPDVMGFNTGAWSGVLVAMVLFGQhlTAIALAAMAGGIVTSLIV 132
Cdd:TIGR03869  48 IVWDLRLPRVLTAAAVGAGLAIAGAVMQSLTRNPLADPYLLGLSSGASLGAVAVLVLGVA--VLLPVAAFAGALLALAAT 125
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446402200  133 WLLAWRNGIETFRLIIIGIGIRAMLVAFNTWLLL--QASLETALTAGLWNAGSLNGLTWAKTWPSAPLIIVMLTGAALLV 210
Cdd:TIGR03869 126 LGLARTLGTLTPTRTILAGLAVSQLCAAVTSFVIfwSATGDSYREILSWLMGSLAGATWGSVAIAGGALLVVGLVLLASG 205
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446402200  211 RRMRLLEMGDDSACALGVSVERSRLMLMLVAVSLTAAATALAGPISFIALVAPHIARRLSGTA-RWGLTQSALCGALLLL 289
Cdd:TIGR03869 206 RVLDAFAFGDSSAAALGVDVERTRWLLLTLVALLTGALVSVSGAIGFVGLILPHAVRLLTGPRhRLLLPVSALAGAVFLV 285
                         250       260       270
                  ....*....|....*....|....*....|....*...
gi 446402200  290 AADACAQQLFMPYQLPVGVVTVSLGGIYLIVLLIQESR 327
Cdd:TIGR03869 286 WADTLARTVFAPRELPVGIITALIGAPVFAVLLYRSRS 323
 
Name Accession Description Interval E-value
PRK10440 PRK10440
iron-enterobactin ABC transporter permease;
1-329 1.75e-172

iron-enterobactin ABC transporter permease;


Pssm-ID: 182463  Cd Length: 330  Bit Score: 481.52  E-value: 1.75e-172
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446402200   1 MFLSRRLIVSCLLLAAGCFAIGLWSLQSGAVPLDTGQIIAALLGDAPRNITLVVTEWRLPRVLMALLIGAALGVSGAIFQ 80
Cdd:PRK10440   2 IYVSRRLLITCLLLLAACVAAGLWGLRSGAVTLETSQVFAALMGDAPRSMTMVVTEWRLPRVLMALLIGAALGVSGAIFQ 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446402200  81 SLMRNPLGSPDVMGFNTGAWSGVLVAMVLFGQHLTAIALAAMAGGIVTSLIVWLLAWRNGIETFRLIIIGIGIRAMLVAF 160
Cdd:PRK10440  82 SLMRNPLGSPDVMGFNTGAWSGVLVAMVLFGQDLTAIALAAMAGGIVTSLLVWLLAWRNGIDTFRLIIIGIGVRAMLVAF 161
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446402200 161 NTWLLLQASLETALTAGLWNAGSLNGLTWAKTWPSAPLIIVMLTGAALLVRRMRLLEMGDDSACALGVSVERSRLMLMLV 240
Cdd:PRK10440 162 NTWLLLKASLETALTAGLWNAGSLNGLTWAKTSPSAPIIILMLIAAALLVRRMRLLEMGDDTACALGVSVERSRLLLMLV 241
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446402200 241 AVSLTAAATALAGPISFIALVAPHIARRLSGTARWGLTQSALCGALLLLAADACAQQLFMPYQLPVGVVTVSLGGIYLIV 320
Cdd:PRK10440 242 AVVLTAAATALAGPISFIALVAPHIARRLSGTARWGLTQAALCGALLLLAADLCAQQLFMPYQLPVGVVTVSLGGIYLIV 321

                 ....*....
gi 446402200 321 LLIQESRKK 329
Cdd:PRK10440 322 LLIQESRKK 330
FepG COG4779
ABC-type enterobactin transport system, permease component [Inorganic ion transport and ...
3-328 1.14e-109

ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 443810  Cd Length: 344  Bit Score: 322.84  E-value: 1.14e-109
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446402200   3 LSRRLIVSCLLLAAGCFAIGLWSLQSGAVPLDTGQIIAALLGDAPRNITLVVTEWRLPRVLMALLIGAALGVSGAIFQSL 82
Cdd:COG4779   18 LRRRALLVTLVLLLLLLALAVLALTLGDYPLSPGDVLRALLGEGDPGASFVVLELRLPRALAALLVGAALGLSGAIFQSL 97
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446402200  83 MRNPLGSPDVMGFNTGAWSGVLVAMVLFGQHLTAIALAAMAGGIVTSLIVWLLAWRNGIETFRLIIIGIGIRAMLVAFNT 162
Cdd:COG4779   98 TRNPLASPDIIGITAGASAGAVAAIVVLGGSGLAVALGALAGGLATALLVYLLAWRGGVSGYRLILVGIGVSAMLTAVNS 177
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446402200 163 WLLLQASLETALTAGLWNAGSLNGLTWAKTWPSAPLIIVMLTGAALLVRRMRLLEMGDDSACALGVSVERSRLMLMLVAV 242
Cdd:COG4779  178 YLLTRADLEDAQSAAVWLTGSLNGRTWEDVLPLAVALAVLLPLALALARRLRLLELGDDTAAALGVRVERTRLLLLLVAV 257
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446402200 243 SLTAAATALAGPISFIALVAPHIARRLSGTARWGLTQSALCGALLLLAADACAQQLFMPYQLPVGVVTVSLGGIYLIVLL 322
Cdd:COG4779  258 ALAAVATAAAGPIAFVALAAPQIARRLTRSPGPPLLPSALVGALLLLAADLVAQHLLAPVQLPVGVVTGALGGPYLLWLL 337

                 ....*.
gi 446402200 323 IQESRK 328
Cdd:COG4779  338 IRENRR 343
FecCD pfam01032
FecCD transport family; This is a sub-family of bacterial binding protein-dependent transport ...
20-324 5.30e-60

FecCD transport family; This is a sub-family of bacterial binding protein-dependent transport systems family. This Pfam entry contains the inner components of this multicomponent transport system.


Pssm-ID: 426003  Cd Length: 311  Bit Score: 194.67  E-value: 5.30e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446402200   20 AIGLWSLQSGAVPLDTGQIIAALLGDAPRNITLVVTEWRLPRVLMALLIGAALGVSGAIFQSLMRNPLGSPDVMGFNTGA 99
Cdd:pfam01032   4 LLILLSLFIGAVKISPSDVFSALLGGDDSLAALIVLDLRLPRVLAALLVGAALAVSGALLQTVTRNPLADPSILGISSGA 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446402200  100 WSGVLVAMVLFG-QHLTAIALAAMAGGIVTSLIVWLLA-WRNGIETFRLIIIGIGIRAMLVAFNTWLLLQASLETALTAG 177
Cdd:pfam01032  84 ALGAVLAILLGGsLSLFALPLAAFIGALLAALLVYFLSrGRGGASPLRLILAGIAVSALLSALTSLLLLLLNPEALQSIL 163
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446402200  178 LWNAGSLNGLTWAKTWPSAPLIIVMLTGAALLVRRMRLLEMGDDSACALGVSVERSRLMLMLVAVSLTAAATALAGPISF 257
Cdd:pfam01032 164 FWLMGSLSGANWSDVLILLPLLLIGLILLLLLARKLNLLSLGDDTAKSLGVNVNRVRLLLLLLASLLTAASVAVVGPIGF 243
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446402200  258 IALVAPHIARRLSGTA-RWGLTQSALCGALLLLAADACAQQLFMPYQLPVGVVTVSLGGIYLIVLLIQ 324
Cdd:pfam01032 244 VGLIVPHIARLLVGANhRRLLPLSALLGALLLLLADILARTILSPYELPVGIVTALIGAPFFIYLLLR 311
FepD COG0609
ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and ...
25-323 3.39e-57

ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440374  Cd Length: 306  Bit Score: 187.20  E-value: 3.39e-57
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446402200  25 SLQSGAVPLDTGQIIAALLGDAPRNIT-LVVTEWRLPRVLMALLIGAALGVSGAIFQSLMRNPLGSPDVMGFNTGAWSGV 103
Cdd:COG0609    1 SLSLGAVPISLSDVLRALLGPDGDPTAdLIVWDLRLPRVLLALLVGAALAVAGALMQGLTRNPLADPGILGVSSGAALGA 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446402200 104 LVAMVLFGQ-HLTAIALAAMAGGIVTSLIVWLLAWRN-GIETFRLIIIGIGIRAMLVAFNTWLLLQASLETALTAGLWNA 181
Cdd:COG0609   81 VLAIVLGGGlSALGLPLAAFLGALLAALLVYLLARRGgGLSPLRLVLAGVAVSALFSALTSLLLLLADPEQLRSIVFWLM 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446402200 182 GSLNGLTWAKTWPSAPLIIVMLTGAALLVRRMRLLEMGDDSACALGVSVERSRLMLMLVAVSLTAAATALAGPISFIALV 261
Cdd:COG0609  161 GSLAGASWDDVLLLLPVLLIGLLLALLLARALNALALGDETARSLGVNVERLRLLLLLLAALLTGAAVAVAGPIGFVGLV 240
                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446402200 262 APHIARRLSGT-ARWGLTQSALCGALLLLAADACAQQLFMPYQLPVGVVTVSLGGIYLIVLLI 323
Cdd:COG0609  241 VPHIARLLVGPdHRRLLPASALLGALLLLLADTLARTILAPAELPVGIVTALIGAPFFLYLLR 303
PRK10577 PRK10577
Fe(3+)-hydroxamate ABC transporter permease FhuB;
54-328 1.40e-42

Fe(3+)-hydroxamate ABC transporter permease FhuB;


Pssm-ID: 236720 [Multi-domain]  Cd Length: 668  Bit Score: 155.77  E-value: 1.40e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446402200  54 VTEWRLPRVLMALLIGAALGVSGAIFQSLMRNPLGSPDVMGFNTGAWSGVLVAMVLFGQH-LTAIALAAMAGGIVTSLIV 132
Cdd:PRK10577 393 LLPLRLPRLLAALLAGAMLAVAGTLLQRLTRNPLASPEVLGISSGAGLGVVLALFLVPGAgFGWLLAAALLGALAALALI 472
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446402200 133 WLLAWRNGIETFRLIIIGIGIRAMLVAFNTWLLLQASLETAlTAGLWNAGSLNGLTWAKTWPSAPLIIVMLTGAALLVRR 212
Cdd:PRK10577 473 LLLARRGGFAPERLLLTGIALSALFTALIQLLLASGDPRAA-QLLTWLSGSTYGVTWAQALPLLIVAVLLLALALLLRRW 551
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446402200 213 MRLLEMGDDSACALGVSVERSRLMLMLVAVSLTAAATALAGPISFIALVAPHIARRLSG-TARWGLTQSALCGALLLLAA 291
Cdd:PRK10577 552 LDLLPLGDDTARALGLPVTRARLALLLLAALLTAAATATVGPLSFVGLMAPHLARMLGGrRARPQLVLAALLGALLMVLA 631
                        250       260       270
                 ....*....|....*....|....*....|....*..
gi 446402200 292 DACAQQLFMPYQLPVGVVTVSLGGIYLIVLLIQESRK 328
Cdd:PRK10577 632 DWLGRTLLFPYQIPAGLLAALIGAPYFLWLLRRSRRR 668
PRK10577 PRK10577
Fe(3+)-hydroxamate ABC transporter permease FhuB;
4-322 1.23e-40

Fe(3+)-hydroxamate ABC transporter permease FhuB;


Pssm-ID: 236720 [Multi-domain]  Cd Length: 668  Bit Score: 150.37  E-value: 1.23e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446402200   4 SRRLIVSCLLLAAGCFAIGLWSLQSGAVPLDTGQIIAALLGDAPRNI-TLVVTEWRLPRVLMALLIGAALGVSGAIFQSL 82
Cdd:PRK10577   7 RRRARLPALLLALLLLLALALTLTQLSAALPLSQWLQALWGPDADDLeQLLLHYSRLPRLAIALLVGAALGLAGALLQQV 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446402200  83 MRNPLGSPDVMGFNTGAWSGVLVAMVLFGQHLTAIA-LAAMAGGIVTSLIVWLLAWRNGIETFRLIIIGIGIRAMLVAFN 161
Cdd:PRK10577  87 LRNPLASPTTLGVAAGAQLALVLATLFAPALLALASqLAAFAGGLLAAALVFALAGGKRLSPLRLVLAGMVVSLYLGALT 166
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446402200 162 TWLLLqASLETALTAGLWNAGSLNGLTWAKTWPSAPLIIVMLTGAALLVRRMRLLEMGDDSACALGVSVERSRLMLMLVA 241
Cdd:PRK10577 167 TLLLL-FNEQYLQGLFLWGAGSLAQNDWSGVQRLLPRLLVGLLLLLLLARPLTLLGLGDDVARSLGLAVSLTRLAALALA 245
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446402200 242 VSLTAAATALAGPISFIALVAPHIARRLSG-TARWGLTQSALCGALLLLAADACAQQL--FMPYQLPVGVVTVSLGGIYL 318
Cdd:PRK10577 246 VLLSAAVVSAVGPIGFIGLAAPNLARLLGArRLRARLPLSPLIGALLLLLTDQLVRLLagVGGELLPTGAVTALIGAPLL 325

                 ....
gi 446402200 319 IVLL 322
Cdd:PRK10577 326 LWLL 329
fecD PRK09777
Fe(3+) dicitrate ABC transporter permease subunit FecD;
5-324 3.15e-38

Fe(3+) dicitrate ABC transporter permease subunit FecD;


Pssm-ID: 182071  Cd Length: 318  Bit Score: 138.26  E-value: 3.15e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446402200   5 RRLIVSCLLLAAGCFaigLWSLQSGAVPLDTGQIIAALLGDAPRNITLvvTEWRLPRVLMALLIGAALGVSGAIFQSLMR 84
Cdd:PRK09777   3 IALVIFITLALAGCA---LLSLRMGVIPLPWRALLTDWQAGDEHYYVL--MEYRLPRLLLALFVGAALAVSGVLVQGIVR 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446402200  85 NPLGSPDVMGFNTGAWSGVLVAMVLF-GQHLTAIALAAMAGGIVTSLIVWLLAWRNgiETFRLIIIGIGIRAMLVAFNTW 163
Cdd:PRK09777  78 NPLASPDILGVNHAASLASVGALLLFpSLPVMWLPLLAFIGGMAGLILLKMLAGTH--QPMKLALTGVALSALWASLTDY 155
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446402200 164 LLLQASLETAlTAGLWNAGSLNGLTWAKTWPSAPLIIVMLTGAALLVRRMRLLEMGDDSACALGVSVERSRLMLMLVAVS 243
Cdd:PRK09777 156 LMLSRPQDIN-NALLWLTGSLWGRDWSFVKVALPWLILLLPLSLSFCRDLDLLALGDARATTLGVSVPHTQFWALLLAVA 234
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446402200 244 LTAAATALAGPISFIALVAPHIARRL-SGTARWGLTQSALCGALLLLAADACAQQLFMPYQLPVGVVTVSLGGIYLIVLL 322
Cdd:PRK09777 235 LTATGVAACGPISFIGLVVPHLMRSLvGGRHRRLLPVSALTGALLLLLADLLARIIHPPLELPAGVLTAIIGAPWFFWLL 314

                 ..
gi 446402200 323 IQ 324
Cdd:PRK09777 315 VR 316
TM_ABC_iron-siderophores_like cd06550
Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
62-322 4.53e-37

Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of a PBP, two TMs, and two cytoplasmic ABCs, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The TMs are bundles of alpha helices that transverse the cytoplasmic membrane multiple times. The two ABCs bind and hydrolyze ATP and drive the transport reaction. Each TM has a prominent cytoplasmic loop which contacts an ABC and represents a conserved motif. The two TMs form either a homodimer (e.g. in the case of the BtuC subunits of the Escherichia coli BtuCD vitamin B12 transporter), a heterodimer (e.g. the TroC and TroD subunits of the Treponema pallidum general transition metal transporter, TroBCD), or a pseudo-heterodimer (e.g. the FhuB protein of the E. coli ferrichrome transporter, FhuBC). FhuB contains two tandem TMs which associate to form the pseudo-heterodimer. Both FhuB TMs are found in this hierarchy.


Pssm-ID: 119348 [Multi-domain]  Cd Length: 261  Bit Score: 133.45  E-value: 4.53e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446402200  62 VLMALLIGAALGVSGAIFQSLMRNPLGSPDVMGFNTGAWSGVLVAMVLFGQH-LTAIALAAMAGGIVTSLIVWLLAWRNG 140
Cdd:cd06550    1 LLAALLVGAALAVSGAILQSLTRNRLASPSILGISHGALLGVVLALLLGIGLsNYALGAFAFAGALAIALLVLLLASRGG 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446402200 141 IETFRLIIIGIGIRAMLVAFNTWLLLQASlETALTAGLWNAGSLNGLTWAKTWPSAPLIIVMLTGAALLVRRMRLLEMGD 220
Cdd:cd06550   81 LSPSKLILIGIVLSAFFSAGVILISLLSD-DSLQDLNIWLFGSILGVTWEDLLILLIILLLVLLLLLLLSRKLNLLTFDE 159
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446402200 221 DSACALGVSVERSRLMLMLVAVSLTAAATALAGPISFIALVAPHIARRLSGTARWGLTQSALCGALLLLAADACAQQLFM 300
Cdd:cd06550  160 DLAKSLGINVNLLRLLLLLLVALLVVAAVALVGVILFVGLIAPHLARRLFGRSHRYLLPLSALLGAILLLLGDLLSRTLL 239
                        250       260
                 ....*....|....*....|..
gi 446402200 301 PYQLPVGVVTVSLGGIYLIVLL 322
Cdd:cd06550  240 PSELPVGPVTALLGAPYFLYLL 261
fecC PRK11228
iron-dicitrate ABC transporter permease FecC;
40-314 6.10e-28

iron-dicitrate ABC transporter permease FecC;


Pssm-ID: 183042  Cd Length: 323  Bit Score: 110.55  E-value: 6.10e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446402200  40 AALLGDAPRNITLVVTEWRLPRVLMALLIGAALGVSGAIFQSLMRNPLGSPDVMGFNTGAWSGVLVAMVLFGQHLT--AI 117
Cdd:PRK11228  33 ALLPGHTPTLPEALVQNLRLPRSLVAVLIGASLALAGALLQTLTHNPLASPSLLGINSGAALAMALTSALSPTPFAgySL 112
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446402200 118 ALAAMAGGIVTSLIVWLL--AWRNGIETFRLIIIGIGIRAMLVAFNTWLLLQASlETALTAGLWNAGSLNGLTWAKTWPS 195
Cdd:PRK11228 113 AFIAACGGGLSWLLVMTAggGWRHTHDRNRLILAGIALSALCMALTRITLLLAE-DHAYGIFYWLAGGVSHARWQEVWQL 191
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446402200 196 APLIIVMLTGAALLVRRMRLLEMGDDSACALGVSVERSRLMLMLVAVSLTAAATALAGPISFIALVAPHIARRLSG-TAR 274
Cdd:PRK11228 192 LPFVVTAVPVVLLLANQLNLLNLSDSSAHTLGVNLTRLRLVVNMLVLLLVGACVSVAGPVAFIGLLVPHLARFWIGyDQR 271
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|
gi 446402200 275 WGLTQSALCGALLLLAADACAQQLFMPYQLPVGVVTVSLG 314
Cdd:PRK11228 272 NVLPMSMLLGATLMLLADLLARALAFPGELPAGAVLALIG 311
BtuC COG4139
ABC-type cobalamin transport system, permease component BtuC [Coenzyme transport and ...
52-323 8.54e-27

ABC-type cobalamin transport system, permease component BtuC [Coenzyme transport and metabolism];


Pssm-ID: 443314  Cd Length: 327  Bit Score: 107.63  E-value: 8.54e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446402200  52 LVVTEWRLPRVLMALLIGAALGVSGAIFQSLMRNPLGSPDVMGFNTGAWSGVLVAMVLFGQHLT--AIALAAMAGGIVTS 129
Cdd:COG4139   49 LFVWQLRLPRTLAAVLVGASLAVSGAVMQALFENPLAEPGLLGISNGAGVGLVLVVLLGGGLLPpwLLSLAAIAGALLVT 128
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446402200 130 LIVWLLAwRNGIETFRLIIIGIGIRAMLVAFNTWLLLQASLETALTAGLWNAGSLNGLTWAKTWPSAPLIIVMLtGAALL 209
Cdd:COG4139  129 LLLLAFA-RRRLSNARLLLIGVALGIICSAIMTWAVYFSSSLDLRQLMYWMMGSFGGVDWRQLWLLLALLPVLL-WLCLQ 206
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446402200 210 VRRMRLLEMGDDSACALGVSVERSRLMLMLVAVSLTAAATALAGPISFIALVAPHIARRLSGT-ARWGLTQSALCGALLL 288
Cdd:COG4139  207 GKPLNLLLLGENQARQLGLSVHRWRNLLVLATGLLVGVSVALAGPIGFVGLVVPHLLRLLGTTdHRFLLPACALAGAALL 286
                        250       260       270
                 ....*....|....*....|....*....|....*
gi 446402200 289 LAADACAQQLFMPYQLPVGVVTVSLGGIYLIVLLI 323
Cdd:COG4139  287 LLADIIARLALSSAELPIGVVTATLGAPVFIWLLL 321
btuC PRK09535
cobalamin ABC transporter permease BtuC;
45-322 1.18e-26

cobalamin ABC transporter permease BtuC;


Pssm-ID: 236553  Cd Length: 366  Bit Score: 107.91  E-value: 1.18e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446402200  45 DAPRNITLVVTEWRLPRVLMALLIGAALGVSGAIFQSLMRNPLGSPDVMGFNTGAWSGVLVAMVLFGQHLTAIALAAMAG 124
Cdd:PRK09535  82 AVPETAQTIVLQIRLPRILLAATVGFALAAAGTVMQGFFRNPMADPSIIGVSSGAAVGAVAAIVLPLAVPFGLQAAAFAG 161
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446402200 125 GIVTSLIVWLLAWRNG-IETFRLIIIGIGIRAMLVAFNTWLLLQA--SLETALtagLWNAGSLNGLTWAKTWPSAPLIIV 201
Cdd:PRK09535 162 ALVAAFGVYAIATENGrTPVATLLLAGVAVQTFLGAVISYLLLHSgeSLRRAV---YWLMGHLHGSTWSDVEVALPVVVV 238
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446402200 202 MLTGAALLVRRMRLLEMGDDSACALGVSVERSRLMLMLVAVSLTAAATALAGPISFIALVAPHIARRLSGTARWGLTQSA 281
Cdd:PRK09535 239 GFVVLLAYARDLNVLLLGEEDAHTLGIEVERTKRLLLALASVVTAAAVAVAGVIGFVGLIVPHVMRLLVGPDHRILLPTS 318
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|.
gi 446402200 282 LCGALLLLAADACAQQLfMPYQLPVGVVTVSLGGIYLIVLL 322
Cdd:PRK09535 319 ALAGASFLVATDTVARS-GPAEVPVGIVTAALGAPFFLYLL 358
PRK10441 PRK10441
Fe(3+)-siderophore ABC transporter permease;
1-327 1.43e-25

Fe(3+)-siderophore ABC transporter permease;


Pssm-ID: 182464  Cd Length: 335  Bit Score: 104.40  E-value: 1.43e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446402200   1 MFLSRRLIVSCLLLAAGCFAIGLwSLQSGAVPLDTGQIIAALLGDAPRNITLVVTEWRLPRVLMALLIGAALGVSGAIFQ 80
Cdd:PRK10441   4 SVAVTRAIAVPGLLLLLIIATAL-SLLIGAKSLPASVVLEALSGTCQSADCTIVLDARLPRTLAGLLAGGALGLAGALMQ 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446402200  81 SLMRNPLGSPDVMGFNTGAWSGVLVAMVLFGQHLTAIALA-AMAGGIVTSLIVWLLAWRNG--IETFRLIIIGIGIRAML 157
Cdd:PRK10441  83 TLTRNPLADPGLLGVNAGASFAIVLGAALFGYSSAQEQLAmAFAGALVASLIVAFTGSQGGgqLSPVRLTLAGVALAAVL 162
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446402200 158 VAFNTWL-LLQASLETALTagLWNAGSLNGLTWAKTWPSAPLIIVMLTGAALLVRRMRLLEMGDDSACALGVSVERSRLM 236
Cdd:PRK10441 163 EGLTSGIaLLNPDVYDQLR--FWQAGSLDIRNLHTLKVVLIPVLIAGATALLLSRALNSLSLGSDTATALGSRVARTQLI 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446402200 237 LMLVAVSLTAAATALAGPISFIALVAPHIARRLSGT-ARWGLTQSALCGALLLLAADACAqQLFMPYQLPVGVVTVSLGG 315
Cdd:PRK10441 241 GLLAITVLCGSATAVVGPIAFIGLMMPHMARWLVGAdHRWSLPVTLLATPALLLFADIIG-RLLVPGELRVSVVSAFIGA 319
                        330
                 ....*....|..
gi 446402200 316 IYLIVLLIQESR 327
Cdd:PRK10441 320 PVLIFLVRRKTR 331
PRK03784 PRK03784
vtamin B12-transporter permease; Provisional
52-327 3.79e-23

vtamin B12-transporter permease; Provisional


Pssm-ID: 235159  Cd Length: 331  Bit Score: 97.72  E-value: 3.79e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446402200  52 LVVTEWRLPRVLMALLIGAALGVSGAIFQSLMRNPLGSPDVMGFNTGAWSGVLVAMVLFGQHLT--AIALAAMAGGIVTS 129
Cdd:PRK03784  52 LFVWQLRLPRTLAVLLVGAALAVSGAVMQALFENPLAEPGLLGVSNGAGVALVAAVLLGQGLLPpwALSLCAIAGALLIT 131
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446402200 130 LIVWLLAWRNGIETFRLIIIGIGIRAMLVAFNTWLLLQASLETALTAGLWNAGSLNGLTWAKTWPSAPLIIVmLTGAALL 209
Cdd:PRK03784 132 LILLRFARRHRLSTSRLLLAGVALGIICSALMTWAVYFSTSLDLRQLMYWMMGGFGGVDWRQSWLMLALLPV-LIWLCCQ 210
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446402200 210 VRRMRLLEMGDDSACALGVSVERSRLMLMLVAVSLTAAATALAGPISFIALVAPHIARRLSGT-ARWGLTQSALCGALLL 288
Cdd:PRK03784 211 GRPLNMLALGEISARQLGLPLWFWRNLLVLATGWLVGVSVALAGAIGFIGLVIPHILRLCGLTdHRVLLPGCALAGASLL 290
                        250       260       270
                 ....*....|....*....|....*....|....*....
gi 446402200 289 LAADACAQQLFMPYQLPVGVVTVSLGGIYLIVLLIQESR 327
Cdd:PRK03784 291 LLADIVARLALASAELPIGVVTATLGAPVFIWLLLRSHR 329
F420-0_ABCperm TIGR03869
proposed F420-0 ABC transporter, permease protein; his small clade of ABC-type transporter ...
53-327 1.44e-20

proposed F420-0 ABC transporter, permease protein; his small clade of ABC-type transporter permease protein components is found as a three gene cassette along with a periplasmic substrate-binding protein (TIGR03868) and an ATPase (TIGR03873). The organisms containing this cassette are all Actinobacteria and all contain numerous genes requiring the coenzyme F420. This model was defined based on five such organisms, four of which are lacking all F420 biosynthetic capability save the final side-chain polyglutamate attachment step (via the gene cofE: TIGR01916). In Jonesia denitrificans DSM 20603 and marine actinobacterium PHSC20C1 this cassette is in an apparent operon with the cofE gene and, in PHSC20C1, also with an F420-dependent glucose-6-phosphate dehydrogenase (TIGR03554). Based on these observations we propose that this permease protein is a component of a F420-0 (that is, F420 lacking only the polyglutamate tail) transporter.


Pssm-ID: 163581  Cd Length: 325  Bit Score: 90.30  E-value: 1.44e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446402200   53 VVTEWRLPRVLMALLIGAALGVSGAIFQSLMRNPLGSPDVMGFNTGAWSGVLVAMVLFGQhlTAIALAAMAGGIVTSLIV 132
Cdd:TIGR03869  48 IVWDLRLPRVLTAAAVGAGLAIAGAVMQSLTRNPLADPYLLGLSSGASLGAVAVLVLGVA--VLLPVAAFAGALLALAAT 125
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446402200  133 WLLAWRNGIETFRLIIIGIGIRAMLVAFNTWLLL--QASLETALTAGLWNAGSLNGLTWAKTWPSAPLIIVMLTGAALLV 210
Cdd:TIGR03869 126 LGLARTLGTLTPTRTILAGLAVSQLCAAVTSFVIfwSATGDSYREILSWLMGSLAGATWGSVAIAGGALLVVGLVLLASG 205
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446402200  211 RRMRLLEMGDDSACALGVSVERSRLMLMLVAVSLTAAATALAGPISFIALVAPHIARRLSGTA-RWGLTQSALCGALLLL 289
Cdd:TIGR03869 206 RVLDAFAFGDSSAAALGVDVERTRWLLLTLVALLTGALVSVSGAIGFVGLILPHAVRLLTGPRhRLLLPVSALAGAVFLV 285
                         250       260       270
                  ....*....|....*....|....*....|....*...
gi 446402200  290 AADACAQQLFMPYQLPVGVVTVSLGGIYLIVLLIQESR 327
Cdd:TIGR03869 286 WADTLARTVFAPRELPVGIITALIGAPVFAVLLYRSRS 323
CeuC COG4605
ABC-type enterochelin transport system, permease component [Inorganic ion transport and ...
58-328 1.76e-04

ABC-type enterochelin transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 443655  Cd Length: 317  Bit Score: 42.79  E-value: 1.76e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446402200  58 RLPRVLMALLIGAALGVSGAIFQSLMRNPLGSPDVMGFNTgAWSGVLVAMVLF--GQHLTA--------IALAAMAgGIV 127
Cdd:COG4605   39 RGTKLAAMLLVAIAIAVSTVLFQTITNNRILTPSIMGFDS-LYVLIQTLLVFFlgSAGLAAlnpllnflLEVALMV-GFS 116
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446402200 128 TSLIVWLLAwRNGIETFRLIIIGIGIRAMLVAFNTWLLLQ------ASLETALTAglwnagSLNGLTWAKTWPSAPLIIV 201
Cdd:COG4605  117 LLLYRWLFR-GGRRNLHLLLLVGVVLGTLFRSLSSFLQRLidpnefDVLQDRLFA------SFNNVNTDLLLIAAVIVLL 189
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446402200 202 MLTGAALLVRRMRLLEMGDDSACALGVSVER-SRLMLMLVAVsLTAAATALAGPISFIALVAPHIARRLSGTAR--WGLT 278
Cdd:COG4605  190 ALLLLWRLRRRLDVLALGRDQAINLGVDYRRvVRRLLILVAV-LVAVSTALVGPITFLGLLVANLAYQLFGTYRhrYLLP 268
                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|
gi 446402200 279 QSALCGALLLLAADACAQQLFMpYQLPVGVVTVSLGGIYLIVLLIQESRK 328
Cdd:COG4605  269 AAALIGVIALVGGQFVVEHVFN-FSTTLSVIIEFVGGIYFLYLLLRKRRL 317
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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