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Conserved domains on  [gi|446398099|ref|WP_000475954|]
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MULTISPECIES: APC family permease [Salmonella]

Protein Classification

APC family permease( domain architecture ID 11425014)

APC (amino acid/polyamine/organocation) family permease is involved in the uptake of a specific amino acid and/or polyamine substrate with the concomitant import of a proton

Gene Ontology:  GO:0016020|GO:0055085|GO:0022857|GO:0015171|GO:0006865
PubMed:  23177982|24038584|25043943|10931886
SCOP:  4006243
TCDB:  2.A.3.1|2.A.3

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PotE COG0531
Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];
4-456 7.35e-49

Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];


:

Pssm-ID: 440297 [Multi-domain]  Cd Length: 438  Bit Score: 173.93  E-value: 7.35e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446398099   4 NRLASHLERGVIGFPTTLASSVGLIMASPVILTVTSGFGSGGDTFALAVLLAFIMMQAQITTFAEAATLIPTTGSVYDYI 83
Cdd:COG0531    2 SRGESSELKRKLGLFDLVALGVGAIIGAGIFVLPGLAAGLAGPAAILAWLIAGLLALLVALSYAELASAFPRAGGAYTYA 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446398099  84 SCGMGRFFAITGALcAYLIVHIFAGTAETILAGVMALVNFESVSehvamqhnTWMVGVGMVVVFGILNAIGVEVFGKVEV 163
Cdd:COG0531   82 RRALGPLLGFLAGW-ALLLSYVLAVAAVAVAFGGYLSSLFPAGG--------SVLIALVLILLLTLLNLRGVKESAKVNN 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446398099 164 FLTFGMWTTLTIFGLCGILLSPVTHHSGWFGAPldvSNLSGLFGYIGMAMFMFVGCELVTPMAPEIKKAHRTIPRAMalg 243
Cdd:COG0531  153 ILTVLKLLVLLLFIVVGLFAFDPANFTPFLPAG---GGLSGVLAALALAFFAFTGFEAIANLAEEAKNPKRNIPRAI--- 226

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446398099 244 LLAVAGCMFLYGAainrqVNNVVVDAANHIFLLDTPMAIPAFANRVMGHVGQYWLGVGLLLAGCATINTLMAAVPRMIYG 323
Cdd:COG0531  227 ILSLLIVGVLYIL-----VSLALTGVVPYDELAASGAPLADAAEAVFGPWGAILIALGALLSLLGALNASILGASRLLYA 301

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446398099 324 MALDGALPRFLTWLHPRFKTPVIAIAFGVAIPCLHAWYLNGDIDHIVPLilaAVCAWGVAYLLVTLSVVILRIRRPDLPR 403
Cdd:COG0531  302 MARDGLLPKVFAKVHPRFGTPVNAILLTGVIALLLLLLGAASFTALASL---ASVGVLLAYLLVALAVIVLRRRRPDLPR 378

                        410       420       430       440       450
                 ....*....|....*....|....*....|....*....|....*....|...
gi 446398099 404 AYRAPwFPLPQIISSVGIIIAIINIAPpgmnsrDVLIPFGIMLGLTAAYALFW 456
Cdd:COG0531  379 PFRVP-LPLIPILGILLCLFLLYLLGP------GALLIGLVLLAIGLLLYLLY 424
 
Name Accession Description Interval E-value
PotE COG0531
Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];
4-456 7.35e-49

Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];


Pssm-ID: 440297 [Multi-domain]  Cd Length: 438  Bit Score: 173.93  E-value: 7.35e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446398099   4 NRLASHLERGVIGFPTTLASSVGLIMASPVILTVTSGFGSGGDTFALAVLLAFIMMQAQITTFAEAATLIPTTGSVYDYI 83
Cdd:COG0531    2 SRGESSELKRKLGLFDLVALGVGAIIGAGIFVLPGLAAGLAGPAAILAWLIAGLLALLVALSYAELASAFPRAGGAYTYA 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446398099  84 SCGMGRFFAITGALcAYLIVHIFAGTAETILAGVMALVNFESVSehvamqhnTWMVGVGMVVVFGILNAIGVEVFGKVEV 163
Cdd:COG0531   82 RRALGPLLGFLAGW-ALLLSYVLAVAAVAVAFGGYLSSLFPAGG--------SVLIALVLILLLTLLNLRGVKESAKVNN 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446398099 164 FLTFGMWTTLTIFGLCGILLSPVTHHSGWFGAPldvSNLSGLFGYIGMAMFMFVGCELVTPMAPEIKKAHRTIPRAMalg 243
Cdd:COG0531  153 ILTVLKLLVLLLFIVVGLFAFDPANFTPFLPAG---GGLSGVLAALALAFFAFTGFEAIANLAEEAKNPKRNIPRAI--- 226

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446398099 244 LLAVAGCMFLYGAainrqVNNVVVDAANHIFLLDTPMAIPAFANRVMGHVGQYWLGVGLLLAGCATINTLMAAVPRMIYG 323
Cdd:COG0531  227 ILSLLIVGVLYIL-----VSLALTGVVPYDELAASGAPLADAAEAVFGPWGAILIALGALLSLLGALNASILGASRLLYA 301

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446398099 324 MALDGALPRFLTWLHPRFKTPVIAIAFGVAIPCLHAWYLNGDIDHIVPLilaAVCAWGVAYLLVTLSVVILRIRRPDLPR 403
Cdd:COG0531  302 MARDGLLPKVFAKVHPRFGTPVNAILLTGVIALLLLLLGAASFTALASL---ASVGVLLAYLLVALAVIVLRRRRPDLPR 378

                        410       420       430       440       450
                 ....*....|....*....|....*....|....*....|....*....|...
gi 446398099 404 AYRAPwFPLPQIISSVGIIIAIINIAPpgmnsrDVLIPFGIMLGLTAAYALFW 456
Cdd:COG0531  379 PFRVP-LPLIPILGILLCLFLLYLLGP------GALLIGLVLLAIGLLLYLLY 424
AA_permease_2 pfam13520
Amino acid permease;
15-409 7.83e-21

Amino acid permease;


Pssm-ID: 404414 [Multi-domain]  Cd Length: 427  Bit Score: 94.68  E-value: 7.83e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446398099   15 IGFPTTLASSVGLIMASPVIltVTSGFGSGGDTFALAVLLA-FIMMQAQITTFAEAATLIPTTGSVYDYISCGMGRFFAI 93
Cdd:pfam13520   1 LGLLSAFALVIGSVIGSGIF--VAPLVASGGPALIVWGWIAaIIFSLAVGLVYAELSSALPRSGGIYVYLENAFGKFVAF 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446398099   94 TGALCAYLIVHIFAGTAETILAGVMALVNFESVSEHVAMqhnTWMVGVGMVVVFGILNAIGVEVFGKVEVFLT-FGMWTT 172
Cdd:pfam13520  79 LAGWSNWFAYVLGLASSASVAASYLLSALGPDLVPTTWL---TYGIAIAILIIFAIINIRGVRESAKIQNILGiLKLLLP 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446398099  173 LTIFGLCGI-LLSPVTHHSGWFGAPLDVSNLS-GLFGYIGMAMFMFVGCELVTPMAPEIKKahRTIPRAMALGLLAVAGC 250
Cdd:pfam13520 156 LILIIILGLvTADGGGFNLLSGEWHTFFPDGWpGVFAGFLGVLWSFTGFESAANVSEEVKK--RNVPKAIFIGVIIVGVL 233

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446398099  251 MFLYGAAINRQVNNVVVDAANhifllDTPMAIPAFANRVMGHVGQYWLGVGLLLAGCATINTLMAAVPRMIYGMALDGAL 330
Cdd:pfam13520 234 YILVNIAFFGVVPDDEIALSS-----GLGQVAALLFQAVGGKWGAIIVVILLALSLLGAVNTAIVGASRLLYALARDGVL 308

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446398099  331 PRFLTWLHP-RFKTPVIAIAFGVAIPCLHAWYLNGDIDHIVPLILAAVCAWGVAYLLVTLSVVILRIRRPDLPRAYRAPW 409
Cdd:pfam13520 309 PFSRFFAKVnKFGSPIRAIILTAILSLILLLLFLLSPAAYNALLSLSAYGYLLSYLLPIIGLLILRKKRPDLGRIPGRWP 388
2A0303 TIGR00906
cationic amino acid transport permease; [Transport and binding proteins, Amino acids, peptides ...
 66-395 1.10e-11

cationic amino acid transport permease; [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273330 [Multi-domain]  Cd Length: 557  Bit Score: 67.15  E-value: 1.10e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446398099   66 FAEAATLIPTTGSVYDYISCGMGRFFA-ITGAlcaYLIVHIFAGTAETILA--GVMALVNFESVSE----HVAMQHNTWM 138
Cdd:TIGR00906  82 YAEFGARVPKAGSAYLYSYVTVGELWAfITGW---NLILEYVIGTAAVARSwsAYFDELLNKQIGQfrrtYFKLNYDGLA 158

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446398099  139 VGVGMVVVFGILNAIGVEVFGKVEVFLTFGMWTTLTIFGLCGILLSPVTHH--SGWFGAPLDVSN------LSGLFGYIG 210
Cdd:TIGR00906 159 EYPDFFAVCLILLLAVLLSFGVKESAWVNKIFTAINILVLLFVIIAGFTKAdvANWSITEEKGAGgfmpygFTGVLSGAA 238

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446398099  211 MAMFMFVGCELVTPMAPEIKKAHRTIPRAMALGLLAVAGCMFLYGAAINRQVNnvvvdaanhIFLLDTPMAIPAFANRVM 290
Cdd:TIGR00906 239 TCFFAFIGFDAIATTGEEVKNPQRAIPIGIVTSLLVCFVAYFLMSAALTLMMP---------YYLLDPDAPFPVAFEYVG 309

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446398099  291 GHVGQYWLGVGLLLAGCATINTLMAAVPRMIYGMALDGALPRFLTWLHPRFKTPVIAIAFGVAIPCLHAWYLngDIDHIV 370
Cdd:TIGR00906 310 WDPAKYIVAVGALCGMSTSLLGGMFPLPRVIYAMARDGLLFKWLAQINSKTKTPINATVVSGAIAALMAFLF--DLKALV 387

                         330       340
                  ....*....|....*....|....*
gi 446398099  371 PLILAAVCawgVAYLLVTLSVVILR 395
Cdd:TIGR00906 388 DLLSIGTL---LAYSLVAACVLILR 409
PRK11021 PRK11021
putative transporter; Provisional
 172-340 8.71e-05

putative transporter; Provisional


Pssm-ID: 236823 [Multi-domain]  Cd Length: 410  Bit Score: 44.90  E-value: 8.71e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446398099 172 TLTIFGLCGILL--SPVTHHSGWFGAPLDVsNLSGLFGYIGMAMFMFVGCELVTPMAPEIKKAHRTIPRAMALGLLAVA- 248
Cdd:PRK11021 145 ALLIVALVVAIWwaGDIKPADIPFPAPGSI-EWSGLFAALGVMFWCFVGIEAFAHLASEFKNPERDFPRALMIGLLLAGl 223

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446398099 249 ---GCMFL---YGAAINRQVNNVvvdaanhiflldtpmAIPAFANRVMGHVGQYWLGVGLLLAGCATINTLMAAVPRMIY 322
Cdd:PRK11021 224 vywACTVVvlhFPAYGDKQAAAA---------------SLPGIFVQLFGGYALWVICVIGYLACFASVNIYTQSFARLVW 288

                        170
                 ....*....|....*...
gi 446398099 323 GMALDGALPRFLTWLHPR 340
Cdd:PRK11021 289 SQAREGRPPSYLARLSAR 306
 
Name Accession Description Interval E-value
PotE COG0531
Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];
4-456 7.35e-49

Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];


Pssm-ID: 440297 [Multi-domain]  Cd Length: 438  Bit Score: 173.93  E-value: 7.35e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446398099   4 NRLASHLERGVIGFPTTLASSVGLIMASPVILTVTSGFGSGGDTFALAVLLAFIMMQAQITTFAEAATLIPTTGSVYDYI 83
Cdd:COG0531    2 SRGESSELKRKLGLFDLVALGVGAIIGAGIFVLPGLAAGLAGPAAILAWLIAGLLALLVALSYAELASAFPRAGGAYTYA 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446398099  84 SCGMGRFFAITGALcAYLIVHIFAGTAETILAGVMALVNFESVSehvamqhnTWMVGVGMVVVFGILNAIGVEVFGKVEV 163
Cdd:COG0531   82 RRALGPLLGFLAGW-ALLLSYVLAVAAVAVAFGGYLSSLFPAGG--------SVLIALVLILLLTLLNLRGVKESAKVNN 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446398099 164 FLTFGMWTTLTIFGLCGILLSPVTHHSGWFGAPldvSNLSGLFGYIGMAMFMFVGCELVTPMAPEIKKAHRTIPRAMalg 243
Cdd:COG0531  153 ILTVLKLLVLLLFIVVGLFAFDPANFTPFLPAG---GGLSGVLAALALAFFAFTGFEAIANLAEEAKNPKRNIPRAI--- 226

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446398099 244 LLAVAGCMFLYGAainrqVNNVVVDAANHIFLLDTPMAIPAFANRVMGHVGQYWLGVGLLLAGCATINTLMAAVPRMIYG 323
Cdd:COG0531  227 ILSLLIVGVLYIL-----VSLALTGVVPYDELAASGAPLADAAEAVFGPWGAILIALGALLSLLGALNASILGASRLLYA 301

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446398099 324 MALDGALPRFLTWLHPRFKTPVIAIAFGVAIPCLHAWYLNGDIDHIVPLilaAVCAWGVAYLLVTLSVVILRIRRPDLPR 403
Cdd:COG0531  302 MARDGLLPKVFAKVHPRFGTPVNAILLTGVIALLLLLLGAASFTALASL---ASVGVLLAYLLVALAVIVLRRRRPDLPR 378

                        410       420       430       440       450
                 ....*....|....*....|....*....|....*....|....*....|...
gi 446398099 404 AYRAPwFPLPQIISSVGIIIAIINIAPpgmnsrDVLIPFGIMLGLTAAYALFW 456
Cdd:COG0531  379 PFRVP-LPLIPILGILLCLFLLYLLGP------GALLIGLVLLAIGLLLYLLY 424
AA_permease_2 pfam13520
Amino acid permease;
15-409 7.83e-21

Amino acid permease;


Pssm-ID: 404414 [Multi-domain]  Cd Length: 427  Bit Score: 94.68  E-value: 7.83e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446398099   15 IGFPTTLASSVGLIMASPVIltVTSGFGSGGDTFALAVLLA-FIMMQAQITTFAEAATLIPTTGSVYDYISCGMGRFFAI 93
Cdd:pfam13520   1 LGLLSAFALVIGSVIGSGIF--VAPLVASGGPALIVWGWIAaIIFSLAVGLVYAELSSALPRSGGIYVYLENAFGKFVAF 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446398099   94 TGALCAYLIVHIFAGTAETILAGVMALVNFESVSEHVAMqhnTWMVGVGMVVVFGILNAIGVEVFGKVEVFLT-FGMWTT 172
Cdd:pfam13520  79 LAGWSNWFAYVLGLASSASVAASYLLSALGPDLVPTTWL---TYGIAIAILIIFAIINIRGVRESAKIQNILGiLKLLLP 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446398099  173 LTIFGLCGI-LLSPVTHHSGWFGAPLDVSNLS-GLFGYIGMAMFMFVGCELVTPMAPEIKKahRTIPRAMALGLLAVAGC 250
Cdd:pfam13520 156 LILIIILGLvTADGGGFNLLSGEWHTFFPDGWpGVFAGFLGVLWSFTGFESAANVSEEVKK--RNVPKAIFIGVIIVGVL 233

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446398099  251 MFLYGAAINRQVNNVVVDAANhifllDTPMAIPAFANRVMGHVGQYWLGVGLLLAGCATINTLMAAVPRMIYGMALDGAL 330
Cdd:pfam13520 234 YILVNIAFFGVVPDDEIALSS-----GLGQVAALLFQAVGGKWGAIIVVILLALSLLGAVNTAIVGASRLLYALARDGVL 308

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446398099  331 PRFLTWLHP-RFKTPVIAIAFGVAIPCLHAWYLNGDIDHIVPLILAAVCAWGVAYLLVTLSVVILRIRRPDLPRAYRAPW 409
Cdd:pfam13520 309 PFSRFFAKVnKFGSPIRAIILTAILSLILLLLFLLSPAAYNALLSLSAYGYLLSYLLPIIGLLILRKKRPDLGRIPGRWP 388
AA_permease pfam00324
Amino acid permease;
24-357 3.26e-14

Amino acid permease;


Pssm-ID: 366028 [Multi-domain]  Cd Length: 467  Bit Score: 74.66  E-value: 3.26e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446398099   24 SVGLIMASPVILtvtsgFGSGGDTFALAVLLAFIMMQAQITTFAEAATLIPTTGSVYDYISCGMGRFFAITGALcAYLIV 103
Cdd:pfam00324  12 GTGLFVGSGSVL-----GQAGPAGALLGYLISGVVIFLVMLSLGEISTNGPVSGGFYTYASRFLGPSLGFATGW-NYWLS 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446398099  104 HIFAGTAEtiLAGVMALVNFESVSEHVamqHNTWMVGVGMVVVFGILNAIGVEVFGKVEV------FLTFGMWTTLTIFG 177
Cdd:pfam00324  86 WITVLALE--LTAASILIQFWELVPDI---PYLWVWGAVFLVLLTIINLVGVKWYGEAEFwfalikIIAIIGFIIVGIIL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446398099  178 LCGILLSPVTHHSGW----FGAPLDVSNLSGLFGYIGMAMFMFVGCELVTPMAPEIKKAHRTIPRAM--ALGLLAVAGCM 251
Cdd:pfam00324 161 LSGGNPNDGAIFRYLgdngGKNNFPPGFGKGFISVFVIAFFAFTGIELVGIAAGEVKNPEKSIPKAIlqVIWRITIFYIL 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446398099  252 FLYGAAINRQVNNVVVDAANHIFLLDTPMAIPAFANRVMGHVgqywLGVGLLLAGCATINTLMAAVPRMIYGMALDGALP 331
Cdd:pfam00324 241 SLLAIGLLVPWNDPGLLNDSASAASPFVIFFKFLGISGLAPL----INAVILTAALSAANSSLYSGSRMLYSLARDGLAP 316

                         330       340
                  ....*....|....*....|....*.
gi 446398099  332 RFLTWlHPRFKTPVIAIAFGVAIPCL 357
Cdd:pfam00324 317 KFLKK-VDKRGVPLRAILVSMVISLL 341
2A0303 TIGR00906
cationic amino acid transport permease; [Transport and binding proteins, Amino acids, peptides ...
 66-395 1.10e-11

cationic amino acid transport permease; [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273330 [Multi-domain]  Cd Length: 557  Bit Score: 67.15  E-value: 1.10e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446398099   66 FAEAATLIPTTGSVYDYISCGMGRFFA-ITGAlcaYLIVHIFAGTAETILA--GVMALVNFESVSE----HVAMQHNTWM 138
Cdd:TIGR00906  82 YAEFGARVPKAGSAYLYSYVTVGELWAfITGW---NLILEYVIGTAAVARSwsAYFDELLNKQIGQfrrtYFKLNYDGLA 158

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446398099  139 VGVGMVVVFGILNAIGVEVFGKVEVFLTFGMWTTLTIFGLCGILLSPVTHH--SGWFGAPLDVSN------LSGLFGYIG 210
Cdd:TIGR00906 159 EYPDFFAVCLILLLAVLLSFGVKESAWVNKIFTAINILVLLFVIIAGFTKAdvANWSITEEKGAGgfmpygFTGVLSGAA 238

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446398099  211 MAMFMFVGCELVTPMAPEIKKAHRTIPRAMALGLLAVAGCMFLYGAAINRQVNnvvvdaanhIFLLDTPMAIPAFANRVM 290
Cdd:TIGR00906 239 TCFFAFIGFDAIATTGEEVKNPQRAIPIGIVTSLLVCFVAYFLMSAALTLMMP---------YYLLDPDAPFPVAFEYVG 309

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446398099  291 GHVGQYWLGVGLLLAGCATINTLMAAVPRMIYGMALDGALPRFLTWLHPRFKTPVIAIAFGVAIPCLHAWYLngDIDHIV 370
Cdd:TIGR00906 310 WDPAKYIVAVGALCGMSTSLLGGMFPLPRVIYAMARDGLLFKWLAQINSKTKTPINATVVSGAIAALMAFLF--DLKALV 387

                         330       340
                  ....*....|....*....|....*
gi 446398099  371 PLILAAVCawgVAYLLVTLSVVILR 395
Cdd:TIGR00906 388 DLLSIGTL---LAYSLVAACVLILR 409
AnsP COG1113
L-asparagine transporter or related permease [Amino acid transport and metabolism];
13-411 1.18e-11

L-asparagine transporter or related permease [Amino acid transport and metabolism];


Pssm-ID: 440730 [Multi-domain]  Cd Length: 458  Bit Score: 66.68  E-value: 1.18e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446398099  13 GVIG---FpttLASSVGLIMASPVILTVtsgfgsggdtFALAVLLAFIMMQAqittFAEAATLIPTTGSVYDYISCGMGR 89
Cdd:COG1113   29 GAIGtglF---LGSGKAIALAGPAVLLS----------YLIAGLIVFLVMRA----LGEMAVANPVSGSFSDYAREYLGP 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446398099  90 FFA-ITGALcaYLIVHIFAGTAETILAGVMALVNFESVSehvamqhnTWMVGVGMVVVFGILNAIGVEVFGKVE------ 162
Cdd:COG1113   92 WAGfVTGWL--YWFFWVLVGMAEATAVGIYLQFWFPDVP--------QWVWALVFLVLLTAINLLSVKLFGEFEfwfali 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446398099 163 ------VFLTFGMWTTLTIFGLCG---ILLSPVTHHSGWF--GapldvsnLSGLFGYIGMAMFMFVGCELVTPMAPEIKK 231
Cdd:COG1113  162 kvvaivAFIVVGLLLIFFGFGLPGgppAGLSNLWDHGGFFpnG-------IGGVLAALQIVVFAFGGIELVGIAAAEAKD 234

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446398099 232 AHRTIPRAMA----------LGLLAVAGCMFLYgaainrqvNNVVVDAANHIFLLDTpMAIPAFANrVMGHVgqywlgvg 301
Cdd:COG1113  235 PEKTIPKAINsviwrillfyVGSLFVILALVPW--------NQIGAGGSPFVTVFSL-LGIPAAAG-IMNFV-------- 296

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446398099 302 LLLAGCATINTLMAAVPRMIYGMALDGALPRFLTWLHPRfKTPVIAIAFGVAIpCLHAWYLNGDIDHIVPLILAAVCAWG 381
Cdd:COG1113  297 VLTAALSSLNSGLYSTSRMLYSLAERGDAPKFFGKLSKR-GVPVRAILLSAVV-LLIGVVLNYLLPEKAFTFLLSISGFG 374

                        410       420       430
                 ....*....|....*....|....*....|....*
gi 446398099 382 --VAYLLVTLSVVILRIRRPDLPRA---YRAPWFP 411
Cdd:COG1113  375 alFVWLMILVSQLKFRRRLPREGAAalkFKMPGFP 409
LysP COG0833
Amino acid permease [Amino acid transport and metabolism];
50-417 3.90e-08

Amino acid permease [Amino acid transport and metabolism];


Pssm-ID: 440595 [Multi-domain]  Cd Length: 467  Bit Score: 55.56  E-value: 3.90e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446398099  50 LAVLLAFIMMQAQITTFAEAATLIPTTGS--VY--DYISCGMGrfFAItGALcaYLIVHIFAGTAETILAGVMALVNFES 125
Cdd:COG0833   50 LAYLLGGLMVYFLMTSLGELAVAMPVSGSfqTYatRFIDPAFG--FAV-GWN--YWLNWAITVAAELTAAGIIMQYWFPD 124

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446398099 126 VSehvamqhnTWMVGVGMVVVFGILNAIGVEVFGKVE------------VFLTFGmwtTLTIFGLCG---ILLSPVTHHS 190
Cdd:COG0833  125 VP--------VWIWSLLFLALIFLLNALSVKAFGESEfwfslikvitviAFIIVG---LLMIFGIIGghaPGFSNFTTGD 193

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446398099 191 GWFgapldVSNLSGLFGYIGMAMFMFVGCELVTPMAPEIKKAHRTIPRAM---ALGLLAV-AGCMFLYGAAINRQVNNVV 266
Cdd:COG0833  194 GPF-----PGGFLAILGVMMIVGFSFQGTELIGIAAGESENPEKTIPKAIrqvFWRILLFyILAIFVIAALIPYTDAGVA 268

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446398099 267 ----VDAANHIFLldtpmaipAFANRVMGHVgqywLGVGLLLAGcatiNTLMAAVPRMIYGMALDGALPRFLTWLHPRfK 342
Cdd:COG0833  269 espfTLVFERAGI--------PYAADIMNAV----ILTAVLSAG----NSGLYASTRMLWSLAKEGMAPKIFAKLNKR-G 331

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446398099 343 TPVIAIAF--GVAIPCLHAWYLNGDidhIVPLILAAVCawGVAYLLVTLSVVI--LRIRR---------PDLPraYRAPW 409
Cdd:COG0833  332 VPLNALLAtmAVGLLALLSSFFGAG---TVYLWLLSIS--GLTGFIAWLGIAIshYRFRRayvaqggdlEDLK--YKAPL 404


                 ....*...
gi 446398099 410 FPLPQIIS 417
Cdd:COG0833  405 FPFGPIFA 412
2A0308 TIGR00911
L-type amino acid transporter; [Transport and binding proteins, Amino acids, peptides and ...
 66-410 1.28e-06

L-type amino acid transporter; [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273332 [Multi-domain]  Cd Length: 501  Bit Score: 50.90  E-value: 1.28e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446398099   66 FAEAATLIPTTGSVYDYIscgmgrfFAITGALCAYLIVHIFAGTAETILAGVMALVNFESVSEHVAMQHNTWMVGVGMVV 145
Cdd:TIGR00911  97 YAELGTTIPKSGGEYNYI-------LEVFGPLLAFLRLWIELLVIRPGSQAVNALNFAIYILTPVFPDCEVPEWAIRLVA 169

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446398099  146 VFGIL-----NAIGVEVFGKVEVFLTFGMWTTL---TIFGLCGILLSPVTHH---SGWFGAPLDVSNL-----SGLFGYI 209
Cdd:TIGR00911 170 VLCVLlltlvNCLSVKWATRVQDIFTACKLLALlliIITGWVQLGKGGVESLnpkNAFEGTETSAGGIvlafySGIWAYG 249

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446398099  210 GMAMFMFVGCELVTPmapeikkaHRTIPRAMALGLLAVAGCMFLygaainrqVNNVVVDAANHIFLLDTPMAIPAFANRV 289
Cdd:TIGR00911 250 GWNYLNFVTEEVKNP--------YRTLPIAIIISMPIVTFIYVL--------TNIAYFTVLSPEELLASLAVAVDFGERL 313

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446398099  290 MGHVGqyWLGVGLLLAGC-ATINTLMAAVPRMIYGMALDGALPRFLTWLHPRFKTPVIAIAFGVAIPCLHAwyLNGDIDH 368
Cdd:TIGR00911 314 LGVMS--WAMPALVGLSCfGSVNGSLFSSSRLFFVGGREGHLPSLLSMIHVKRLTPLPSLLIVCTLTLLML--FSGDIYS 389

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|..
gi 446398099  369 IVPLIlaaVCAWGVAYLLVTLSVVILRIRRPDLPRAYRAPWF 410
Cdd:TIGR00911 390 LINLI---SFANWLFNALAVAGLLWLRYKRPEMNRPIKVPLF 428
2A0304 TIGR00907
amino acid permease (GABA permease); [Transport and binding proteins, Amino acids, peptides ...
 170-384 4.32e-05

amino acid permease (GABA permease); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273331 [Multi-domain]  Cd Length: 482  Bit Score: 45.89  E-value: 4.32e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446398099  170 WTTLTIFGLCGILLSPVTH--HSGWFgAPLDVSNLSG---------LFGYIgMAMFMFVGCELVTPMAPEIKKAHRTIPR 238
Cdd:TIGR00907 175 WSLLGFLTICITLLACKSPkfNDGKF-VFTNFNNSTGgwkpggfafLLGLL-NPAWSMTGYDGTAHMAEEIENPEVVGPR 252

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446398099  239 AM--ALGLLAVAGCMFLYGAAINRQVNNVVVDAANHIFLLDTpmaipaFANRVMGHVGQYWLGVGLLLAGCATINTLMAA 316
Cdd:TIGR00907 253 AIigAVAIGIVTGFCFNIVLFFSMGDIDSLISSTTGQPIAQI------FYNALGNKAGAIFLLCLILVTSFFCAITCMTA 326

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446398099  317 VPRMIYGMALDGALP--RFLTWLHPRFKTPVIAIAFGVAIPCLHAWYLNGDIDHIVPLILAAVCAWGVAY 384
Cdd:TIGR00907 327 NSRMIYAFSRDGGLPfsPLWSRVNPRTQVPLNAVWLSAVWIILIGLLGLGSSTAFQAIFSVCTVALDVSY 396
PRK11021 PRK11021
putative transporter; Provisional
 172-340 8.71e-05

putative transporter; Provisional


Pssm-ID: 236823 [Multi-domain]  Cd Length: 410  Bit Score: 44.90  E-value: 8.71e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446398099 172 TLTIFGLCGILL--SPVTHHSGWFGAPLDVsNLSGLFGYIGMAMFMFVGCELVTPMAPEIKKAHRTIPRAMALGLLAVA- 248
Cdd:PRK11021 145 ALLIVALVVAIWwaGDIKPADIPFPAPGSI-EWSGLFAALGVMFWCFVGIEAFAHLASEFKNPERDFPRALMIGLLLAGl 223

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446398099 249 ---GCMFL---YGAAINRQVNNVvvdaanhiflldtpmAIPAFANRVMGHVGQYWLGVGLLLAGCATINTLMAAVPRMIY 322
Cdd:PRK11021 224 vywACTVVvlhFPAYGDKQAAAA---------------SLPGIFVQLFGGYALWVICVIGYLACFASVNIYTQSFARLVW 288

                        170
                 ....*....|....*...
gi 446398099 323 GMALDGALPRFLTWLHPR 340
Cdd:PRK11021 289 SQAREGRPPSYLARLSAR 306
frlA PRK11357
amino acid permease;
15-412 3.32e-04

amino acid permease;


Pssm-ID: 183096 [Multi-domain]  Cd Length: 445  Bit Score: 42.92  E-value: 3.32e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446398099  15 IGFPTTLASSVGLIMASPVILTVTSGFGSGGDTF--ALAVLLAFIMMQAQITTFAEAATLIPTTGSVYDYISCGMGRFFA 92
Cdd:PRK11357  10 LGFWAVLAIAVGTTVGSGIFVSVGEVAKAAGTPWltVLAFVIGGLIVIPQMCVYAELSTAYPENGADYVYLKNAGSRPLA 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446398099  93 ItgaLCAYliVHIFAGTAETILAGVMALVN----FESVSEHVAMqhntwMVGVGMVVVFGILNAIGVEVFGKVEVFLTFG 168
Cdd:PRK11357  90 F---LSGW--ASFWANDAPSLSIMALAIVSnlgfLTPIDPLLGK-----FIAAGLIIAFMLLHLRSVEGGAAFQTLITIA 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446398099 169 MWTTLTIFGLCGILLSpvthHSGWFGAPLDVS-----NLSGLFGYIGMAMFMFVGCELVTPMAPEIKKAHRTIPRAMALG 243
Cdd:PRK11357 160 KIIPFTIVIGLGIFWF----KAENFAAPTTTAigatgSFMALLAGISATSWSYTGMASICYMTGEIKNPGKTMPRALIGS 235

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446398099 244 LLAVAGCMFLYGAAINRQVNNVVVDAAnhifllDTPMAIPAFANRVMGHVGQYWLGVGLLLAGCATINTLMAAVPRMIYG 323
Cdd:PRK11357 236 CLLVLVLYTLLALVISGLMPFDKLANS------ETPISDALTWIPALGSTAGIFVAITAMIVILGSLSSCVMYQPRLEYA 309

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446398099 324 MALDGALPRFLTWLHPRFKTPVIAIAFGVAIPCLHAWYlnGDIDHIVPLILAAVCawgVAYLLVTLSVVILRiRRPDLPR 403
Cdd:PRK11357 310 MAKDNLFFKCFGHVHPKYNTPDVSIILQGALGIFFIFV--SDLTSLLGYFTLVMC---FKNTLTFGSIIWCR-KRDDYKP 383


                 ....*....
gi 446398099 404 AYRAPWFPL 412
Cdd:PRK11357 384 LWRTPAFGL 392
proY PRK10580
putative proline-specific permease; Provisional
 137-413 4.22e-04

putative proline-specific permease; Provisional


Pssm-ID: 182566 [Multi-domain]  Cd Length: 457  Bit Score: 42.88  E-value: 4.22e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446398099 137 WMVGVGMVVVFGILNAIGVEVFGKVEVFLTFGMWTTLTIFGLCGILLspVTHHSGWFGAPLDVSNL---SGLF--GYIGM 211
Cdd:PRK10580 124 WIWVLSVVLIICAVNLMSVKVFGELEFWFSFFKVATIIIMIVAGIGI--IIWGIGNGGQPTGIHNLwsnGGFFsnGWLGM 201

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446398099 212 ------AMFMFVGCELVTPMAPEIKKAHRTIPRAMA----------LGLLAVAGCMFLYgaainrqvnNVVVDAANHIFL 275
Cdd:PRK10580 202 vmslqmVMFAYGGIEIIGITAGEAKDPEKSIPRAINsvpmrilvfyVGTLFVIMSIYPW---------NQVGTNGSPFVL 272

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446398099 276 LDTPMAIpAFANRVMGHVgqywlgvgLLLAGCATINTLMAAVPRMIYGMALDGALPRFLTWLHPRFKTPVIAIAFGVAIp 355
Cdd:PRK10580 273 TFQHMGI-TFAASILNFV--------VLTASLSAINSDVFGVGRMLHGMAEQGSAPKIFSKTSRRGIPWVTVLVMTTAL- 342

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 446398099 356 cLHAWYLNGDIDHIVPLILAAVCAWGVAYLLVTLSVVILRIRRPDLPRAYRAPWFPLP 413
Cdd:PRK10580 343 -LFAVYLNYIMPENVFLVIASLATFATVWVWIMILLSQIAFRRRLPPEEVKALKFKVP 399
PRK10836 PRK10836
lysine transporter; Provisional
 149-337 7.18e-03

lysine transporter; Provisional


Pssm-ID: 182767  Cd Length: 489  Bit Score: 39.03  E-value: 7.18e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446398099 149 ILNAIGVEVFGKVEVFLTFGMWTTLTIFGLCGILL----SPVTHHSGWFGAPLDVSNLSGLF-GYIGMAM---FMFVGCE 220
Cdd:PRK10836 143 LLNYISVRGFGEAEYWFSLIKVTTVIVFIIVGVLMiigiFKGAEPAGWSNWTIGDAPFAGGFaAMIGVAMivgFSFQGTE 222

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446398099 221 LVTPMAPEIKKAHRTIPRA--------MALGLLAVAGCMFLYGAAINRQVNNVVVDAANHIFLLDTPMAIPAFANRVMGH 292
Cdd:PRK10836 223 LIGIAAGESEDPAKNIPRAvrqvfwriLLFYVFAILIISLIIPYTDPSLLRNDVKDISVSPFTLVFQHAGLLSAAAVMNA 302

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 446398099 293 VgqywlgvgLLLAGCATINTLMAAVPRMIYGMALDGALPRFLTWL 337
Cdd:PRK10836 303 V--------ILTAVLSAGNSGMYASTRMLYTLACDGKAPRIFAKL 339
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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