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Conserved domains on  [gi|446390146|ref|WP_000468001|]
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methionine ABC transporter permease [Staphylococcus aureus]

Protein Classification

methionine ABC transporter permease( domain architecture ID 10005172)

methionine ABC transporter permease is the transmembrane (TM) subunit of the ABC transporter complex, such as MetNPQ, that is involved in methionine import, and is responsible for the translocation of the substrate across the membrane

EC:  7.4.2.11
Gene Ontology:  GO:0033232|GO:0048473|GO:0042626
PubMed:  22095702|11421270|25750732|24638992
TCDB:  3.A.1.24

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
MetP COG2011
ABC-type methionine transport system, permease component [Amino acid transport and metabolism]; ...
 9-219 2.91e-82

ABC-type methionine transport system, permease component [Amino acid transport and metabolism];


:

Pssm-ID: 441614  Cd Length: 220  Bit Score: 244.19  E-value: 2.91e-82
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446390146   9 AQLVQALYETLYMVSIALFLGAVIGIPLGVLLVITRKQGIWPNIVIHQVLNPLINILRSLPFIILLIAIVPFTKLVVGTS 88
Cdd:COG2011   10 PLLLQATGETLYMVGVSTLIAVLLGLPLGVLLVLTRPGGLLPNPVLYRVLGVIVNIFRSIPFIILLVALIPLTRLIVGTS 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446390146  89 IGTTAAIVPLTVYVAPYIARLVENSLLEVDEGIIEAAKAMGASPLQIIRYFLIPEALGSLVLAITTAIIGLIGSTAMAGA 168
Cdd:COG2011   90 IGTTAAIVPLTIAAIPFFARLVENALREVDPGVIEAAQAMGASPWQIIFKVLLPEALPSLILGLTVTLISLIGYSAMAGA 169

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 446390146 169 VGGGGIGDLALVYGYQRFDTTVIIITVIVLVIIVQVIQTLGNVLARFIRRH 219
Cdd:COG2011  170 VGGGGLGDLAIRYGYQRFDTDVMLVTVVILIVLVQIIQFLGDRLARRLDHR 220
 
Name Accession Description Interval E-value
MetP COG2011
ABC-type methionine transport system, permease component [Amino acid transport and metabolism]; ...
 9-219 2.91e-82

ABC-type methionine transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 441614  Cd Length: 220  Bit Score: 244.19  E-value: 2.91e-82
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446390146   9 AQLVQALYETLYMVSIALFLGAVIGIPLGVLLVITRKQGIWPNIVIHQVLNPLINILRSLPFIILLIAIVPFTKLVVGTS 88
Cdd:COG2011   10 PLLLQATGETLYMVGVSTLIAVLLGLPLGVLLVLTRPGGLLPNPVLYRVLGVIVNIFRSIPFIILLVALIPLTRLIVGTS 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446390146  89 IGTTAAIVPLTVYVAPYIARLVENSLLEVDEGIIEAAKAMGASPLQIIRYFLIPEALGSLVLAITTAIIGLIGSTAMAGA 168
Cdd:COG2011   90 IGTTAAIVPLTIAAIPFFARLVENALREVDPGVIEAAQAMGASPWQIIFKVLLPEALPSLILGLTVTLISLIGYSAMAGA 169

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 446390146 169 VGGGGIGDLALVYGYQRFDTTVIIITVIVLVIIVQVIQTLGNVLARFIRRH 219
Cdd:COG2011  170 VGGGGLGDLAIRYGYQRFDTDVMLVTVVILIVLVQIIQFLGDRLARRLDHR 220
PRK10782 PRK10782
D-methionine ABC transporter permease MetI;
11-161 5.82e-49

D-methionine ABC transporter permease MetI;


Pssm-ID: 182726  Cd Length: 217  Bit Score: 159.13  E-value: 5.82e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446390146  11 LVQALYETLYMVSIALFLGAVIGIPLGVLLVITRKQGIWPNIVIHQVLNPLINILRSLPFIILLIAIVPFTKLVVGTSIG 90
Cdd:PRK10782   9 LVRGVWETLAMTFVSGFFGFVIGLPVGVLLYVTRPGQIIANAKLYRTLSALVNIFRSIPFIILLVWMIPFTRVIVGTSIG 88

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446390146  91 TTAAIVPLTVYVAPYIARLVENSLLEVDEGIIEAAKAMGASPLQIIRYFLIPEALGSLVLAITTAIIGLIG 161
Cdd:PRK10782  89 LQAAIVPLTVGAAPFIARMVENALLEIPTGLIEASRAMGATPMQIVRKVLLPEALPGLVNAATITLITLVG 159
PhnE TIGR01097
phosphonate ABC transporter, permease protein PhnE; Phosphonates are a class of compound ...
 10-149 7.31e-13

phosphonate ABC transporter, permease protein PhnE; Phosphonates are a class of compound analogous to organic phosphates, but in which the C-O-P linkage is replaced by a direct, stable C-P bond. Some bacteria can utilize phosphonates as a source of phosphorus. This family consists of permease proteins of known or predicted phosphonate ABC transporters. Often this protein is found as a duplicated pair, occasionally as a fused pair. Certain "second" copies score in between the trusted and noise cutoff and should be considered true hits (by context). [Transport and binding proteins, Anions]


Pssm-ID: 273441 [Multi-domain]  Cd Length: 250  Bit Score: 65.64  E-value: 7.31e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446390146   10 QLVQALYETLYMVSIALFLGAVIGIPLGVLLVitrkQGIWPNIVIHQVLNPLINILRSLPFIILliAIVpftkLVVGTSI 89
Cdd:TIGR01097  55 RILKALLETLAMAILGTVLAAVLAVPLALLAA----RNITPSPWLYGLARLLLNFLRAIPELVW--ALI----FVAAVGL 124

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 446390146   90 GTTAAIVPLTVYVAPYIARLVENSLLEVDEGIIEAAKAMGASPLQIIRYFLIPEALGSLV 149
Cdd:TIGR01097 125 GPFAGVLALAFHTVGFLGKLFAEAIEEVDPGPVEALRATGASKLQVIRYGVLPQVLPQFL 184
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 15-163 4.65e-10

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 56.90  E-value: 4.65e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446390146  15 LYETLYMVSIALFLGAVIGIPLGVLLVITRKqgiwpniVIHQVLNPLINILRSLPFIILLIAIVPFTKLVVGTSIG---T 91
Cdd:cd06261    1 LLNTLLLALIATLLALVLGLLLGIILARKRG-------KLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLGWGILpglG 73

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446390146  92 TAAIVPLTVYVAPYIARLVENSLLEVDEGIIEAAKAMGASPLQIIRYFLIPEALGSLVLAITTAIIGLIGST 163
Cdd:cd06261   74 LPALILALLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEF 145
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 33-218 4.01e-07

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 48.45  E-value: 4.01e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446390146   33 GIPLGVLLvitrkqGIWPNIVIHQVLNPLINILRSLPFIILLIAIVPFTKLVVGTSiGTTAAIVPLTVYVAPYIARLVEN 112
Cdd:pfam00528   1 GIPLGIIA------ALRRGRRLDRLLRPLIDLLQALPSFVLAILLVVIAILSILGH-GILPAIILALLGWAGYARLIRRA 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446390146  113 SLLEVDEGIIEAAKAMGASPLQIIRYFLIPEALGSLVLAITTAIIGLIGSTAMAGAVGGGGIGDLALVYGYQRFDTTVII 192
Cdd:pfam00528  74 ALRSLPSDLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSWPGLGLLLIEAILGYDYPEIQ 153

                         170       180
                  ....*....|....*....|....*.
gi 446390146  193 ITVIVLVIIVQVIQTLGNVLARFIRR 218
Cdd:pfam00528 154 GPVLAAALILLLLNLLVDILQRLLDP 179
ABC_perm1 NF038017
ABC transporter permease; Proteins of this family are the permease subunit of an ABC ...
 18-155 1.25e-04

ABC transporter permease; Proteins of this family are the permease subunit of an ABC transporter complex, which may be involved in tungstate uptake.


Pssm-ID: 411610 [Multi-domain]  Cd Length: 184  Bit Score: 41.38  E-value: 1.25e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446390146  18 TLYMVSIALFLGAVIGIPLGVLLVITRKQGiwpniviHQVLNPLINILRSLP-------FIILLIAIVPFTKLvvGTSIG 90
Cdd:NF038017   1 SLRVSGTATLIAALIGIPLGALLALRRFPG-------RRLVISLLNTLMGLPpvvvgliVYLLLSRSGPLGFL--GLLYT 71

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446390146  91 TTAAIVPLTVYVAPYIARLVENSLLEVDEGIIEAAKAMGASPLQIIRyFLIPEALGSLVLAITTA 155
Cdd:NF038017  72 PTAMIIAQAVLALPIVAGLTLAAVQGLDPELRLQILSLGATRWQALW-TLLKEARFALLAAVLAG 135
 
Name Accession Description Interval E-value
MetP COG2011
ABC-type methionine transport system, permease component [Amino acid transport and metabolism]; ...
 9-219 2.91e-82

ABC-type methionine transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 441614  Cd Length: 220  Bit Score: 244.19  E-value: 2.91e-82
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446390146   9 AQLVQALYETLYMVSIALFLGAVIGIPLGVLLVITRKQGIWPNIVIHQVLNPLINILRSLPFIILLIAIVPFTKLVVGTS 88
Cdd:COG2011   10 PLLLQATGETLYMVGVSTLIAVLLGLPLGVLLVLTRPGGLLPNPVLYRVLGVIVNIFRSIPFIILLVALIPLTRLIVGTS 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446390146  89 IGTTAAIVPLTVYVAPYIARLVENSLLEVDEGIIEAAKAMGASPLQIIRYFLIPEALGSLVLAITTAIIGLIGSTAMAGA 168
Cdd:COG2011   90 IGTTAAIVPLTIAAIPFFARLVENALREVDPGVIEAAQAMGASPWQIIFKVLLPEALPSLILGLTVTLISLIGYSAMAGA 169

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 446390146 169 VGGGGIGDLALVYGYQRFDTTVIIITVIVLVIIVQVIQTLGNVLARFIRRH 219
Cdd:COG2011  170 VGGGGLGDLAIRYGYQRFDTDVMLVTVVILIVLVQIIQFLGDRLARRLDHR 220
PRK10782 PRK10782
D-methionine ABC transporter permease MetI;
11-161 5.82e-49

D-methionine ABC transporter permease MetI;


Pssm-ID: 182726  Cd Length: 217  Bit Score: 159.13  E-value: 5.82e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446390146  11 LVQALYETLYMVSIALFLGAVIGIPLGVLLVITRKQGIWPNIVIHQVLNPLINILRSLPFIILLIAIVPFTKLVVGTSIG 90
Cdd:PRK10782   9 LVRGVWETLAMTFVSGFFGFVIGLPVGVLLYVTRPGQIIANAKLYRTLSALVNIFRSIPFIILLVWMIPFTRVIVGTSIG 88

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446390146  91 TTAAIVPLTVYVAPYIARLVENSLLEVDEGIIEAAKAMGASPLQIIRYFLIPEALGSLVLAITTAIIGLIG 161
Cdd:PRK10782  89 LQAAIVPLTVGAAPFIARMVENALLEIPTGLIEASRAMGATPMQIVRKVLLPEALPGLVNAATITLITLVG 159
PhnE COG3639
ABC-type phosphate/phosphonate transport system, permease component [Inorganic ion transport ...
 1-149 6.73e-15

ABC-type phosphate/phosphonate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 442856 [Multi-domain]  Cd Length: 244  Bit Score: 70.88  E-value: 6.73e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446390146   1 MFGSDLD-SAQLVQALYETLYMVSIALFLGAVIGIPLGVLlvITRkqGIWPNIVIHQVLNPLINILRSLPFIILliAIVp 79
Cdd:COG3639   38 FFPPDWSyLPDLLSALLETLAIALLGTLLGAVLALPLAFL--AAR--NLAPNPWVRLLARRLLNVLRAIPELVW--ALI- 110

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446390146  80 ftkLVVGTSIGTTAAIVPLTVYVAPYIARLVENSLLEVDEGIIEAAKAMGASPLQIIRYFLIPEALGSLV 149
Cdd:COG3639  111 ---FVAAVGLGPFAGVLALAIHTIGFLGKLFAEAIEEIDPGPVEALRATGASRLQVIRYGVLPQVLPQFL 177
TauC COG0600
ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion ...
 2-160 1.26e-14

ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440365 [Multi-domain]  Cd Length: 254  Bit Score: 70.56  E-value: 1.26e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446390146   2 FGSDLDSAQLVQALYETLYMVSIALFLGAVIGIPLGVLLVITRkqgiwpniVIHQVLNPLINILRSLPfiilLIAIVPFT 81
Cdd:COG0600   50 LVELLASGELWEHLLASLLRVLLGFALAALLGVPLGLLLGLSR--------LLRRLLDPLLVFLRPIP----PLALAPLL 117

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446390146  82 KLVVGtsIGTTAAIVPLTVYVAPYIARLVENSLLEVDEGIIEAAKAMGASPLQIIRYFLIPEAL----GSLVLAITTAII 157
Cdd:COG0600  118 ILWFG--IGEASKIFVIFLGAFFPILLNTAAGVRSVDPELLELARSLGASRWQILRKVVLPAALpyifTGLRIALGLAWI 195


                 ...
gi 446390146 158 GLI 160
Cdd:COG0600  196 GLV 198
OpuBB COG1174
ABC-type proline/glycine betaine transport system, permease component [Amino acid transport ...
 8-161 1.40e-14

ABC-type proline/glycine betaine transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 440787 [Multi-domain]  Cd Length: 212  Bit Score: 69.70  E-value: 1.40e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446390146   8 SAQLVQALYETLYMVSIALFLGAVIGIPLGVLLVITRKQGiwpnivihQVLNPLINILRSLPFIILLIAIVPFTklvvgt 87
Cdd:COG1174   13 RDGILALLLEHLLLVLLALLIALLIAVPLGILITRRRRLA--------GLVLGVANILQTIPSLALLALLIPLL------ 78

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446390146  88 SIGTTAAIVPLTVYVAPYIARLVENSLLEVDEGIIEAAKAMGASPLQIIRYFLIPEALGSLVLAITTAIIGLIG 161
Cdd:COG1174   79 GIGPAPAIIALVLYALLPILRNTYTGLRSVDPAVVEAARGMGMTPWQRLWRVELPLALPVILAGIRTAAVQNIG 152
PhnE TIGR01097
phosphonate ABC transporter, permease protein PhnE; Phosphonates are a class of compound ...
 10-149 7.31e-13

phosphonate ABC transporter, permease protein PhnE; Phosphonates are a class of compound analogous to organic phosphates, but in which the C-O-P linkage is replaced by a direct, stable C-P bond. Some bacteria can utilize phosphonates as a source of phosphorus. This family consists of permease proteins of known or predicted phosphonate ABC transporters. Often this protein is found as a duplicated pair, occasionally as a fused pair. Certain "second" copies score in between the trusted and noise cutoff and should be considered true hits (by context). [Transport and binding proteins, Anions]


Pssm-ID: 273441 [Multi-domain]  Cd Length: 250  Bit Score: 65.64  E-value: 7.31e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446390146   10 QLVQALYETLYMVSIALFLGAVIGIPLGVLLVitrkQGIWPNIVIHQVLNPLINILRSLPFIILliAIVpftkLVVGTSI 89
Cdd:TIGR01097  55 RILKALLETLAMAILGTVLAAVLAVPLALLAA----RNITPSPWLYGLARLLLNFLRAIPELVW--ALI----FVAAVGL 124

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 446390146   90 GTTAAIVPLTVYVAPYIARLVENSLLEVDEGIIEAAKAMGASPLQIIRYFLIPEALGSLV 149
Cdd:TIGR01097 125 GPFAGVLALAFHTVGFLGKLFAEAIEEVDPGPVEALRATGASKLQVIRYGVLPQVLPQFL 184
DppC COG1173
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 9-160 2.75e-10

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440786 [Multi-domain]  Cd Length: 275  Bit Score: 58.59  E-value: 2.75e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446390146   9 AQLVQALYETLYMVSIALFLGAVIGIPLGVLLVITRKqgiwpniVIHQVLNPLINILRSLPFIILLIAIVpftkLVVGTS 88
Cdd:COG1173   72 SRLLYGARISLLVGLLAVLIALVIGVLLGLLAGYFGG-------WVDAVLMRLVDVLLAFPSLLLAIALV----AVLGPG 140

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446390146  89 IGTtaAIVPLTVYVAPYIARLVENSLLEV-DEGIIEAAKAMGASPLQIIRYFLIPEALGSLVLAITTAIIGLI 160
Cdd:COG1173  141 LLN--VILALGLTGWPGYARLVRAQVLSLrEREYVEAARALGASPLRIIFRHILPNVLPPLIVQATLGIASAI 211
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 15-163 4.65e-10

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 56.90  E-value: 4.65e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446390146  15 LYETLYMVSIALFLGAVIGIPLGVLLVITRKqgiwpniVIHQVLNPLINILRSLPFIILLIAIVPFTKLVVGTSIG---T 91
Cdd:cd06261    1 LLNTLLLALIATLLALVLGLLLGIILARKRG-------KLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLGWGILpglG 73

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446390146  92 TAAIVPLTVYVAPYIARLVENSLLEVDEGIIEAAKAMGASPLQIIRYFLIPEALGSLVLAITTAIIGLIGST 163
Cdd:cd06261   74 LPALILALLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEF 145
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 33-218 4.01e-07

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 48.45  E-value: 4.01e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446390146   33 GIPLGVLLvitrkqGIWPNIVIHQVLNPLINILRSLPFIILLIAIVPFTKLVVGTSiGTTAAIVPLTVYVAPYIARLVEN 112
Cdd:pfam00528   1 GIPLGIIA------ALRRGRRLDRLLRPLIDLLQALPSFVLAILLVVIAILSILGH-GILPAIILALLGWAGYARLIRRA 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446390146  113 SLLEVDEGIIEAAKAMGASPLQIIRYFLIPEALGSLVLAITTAIIGLIGSTAMAGAVGGGGIGDLALVYGYQRFDTTVII 192
Cdd:pfam00528  74 ALRSLPSDLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSWPGLGLLLIEAILGYDYPEIQ 153

                         170       180
                  ....*....|....*....|....*.
gi 446390146  193 ITVIVLVIIVQVIQTLGNVLARFIRR 218
Cdd:pfam00528 154 GPVLAAALILLLLNLLVDILQRLLDP 179
PRK15082 PRK15082
glutathione ABC transporter permease GsiD; Provisional
 24-157 3.99e-06

glutathione ABC transporter permease GsiD; Provisional


Pssm-ID: 185040 [Multi-domain]  Cd Length: 301  Bit Score: 46.65  E-value: 3.99e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446390146  24 IALFLGAVIGIPLGvlLVITRKQGIWPNIVIHqvlnpLINILRSLPFIILLIAIVPftklVVGTSIgtTAAIVPLTVYVA 103
Cdd:PRK15082 108 FSVAIGAAIGTVLG--LLAGYYEGWWDRIIMR-----ICDVLFAFPGILLAIAVVA----ILGSGM--ANVIIAVAIFSI 174

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 446390146 104 PYIARLVE-NSLLEVDEGIIEAAKAMGASPLQIIRYFLIPEALGSLV----LAITTAII 157
Cdd:PRK15082 175 PAFARLVRgNTLVLKQQTYIESARSIGASDWTILLRHILPGTVSSIVvyftMRIGTSII 233
CysU COG0555
ABC-type sulfate transport system, permease component [Inorganic ion transport and metabolism]; ...
 6-149 6.88e-06

ABC-type sulfate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440321 [Multi-domain]  Cd Length: 268  Bit Score: 45.51  E-value: 6.88e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446390146   6 LDSAQLVQALYETLYMVSIALFLGAVIGIPLGVLLVITRKQGiwpniviHQVLNPLINILRSLPFIILLIAIV------- 78
Cdd:COG0555   47 LTSPRVLAALKLSLGTALIAALINLVFGLPLAWVLVRYRFPG-------KRLVDALVDLPFALPTAVAGIALLllfgpng 119

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446390146  79 ----PFTKLVVGTSIGTTAAIVPLTVYVAPYIARLVENSLLEVDEGIIEAAKAMGASPLQIIRYFLIPEALGSLV 149
Cdd:COG0555  120 wlgqLLAPLGIKVAFTPLGIVLAQTFVSLPFVVRTVQPVLEELDPELEEAAATLGASRWQTFRRVILPLLLPALL 194
PotC COG1177
ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport ...
 6-149 9.05e-06

ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism];


Pssm-ID: 440790 [Multi-domain]  Cd Length: 262  Bit Score: 45.10  E-value: 9.05e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446390146   6 LDSAQLVQALYETLYMVSIALFLGAVIGIPLGVLLVITRKQGiwpniviHQVLNPLINILRSLPFIILLIAIVPFTkLVV 85
Cdd:COG1177   54 FSDPRLLDALLNSLLIALLSTLLATVLGTPAALALARYRFRG-------RRLLLALLLLPLVVPGIVLGVALLLLF-SAL 125

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446390146  86 GTSIGTTAAIVPLTVYVAPYIARLVENSLLEVDEGIIEAAKAMGASPLQIIRYFLIPEALGSLV 149
Cdd:COG1177  126 GLSGGLWGLILAHVVFTLPFVVLVVLARLQGFDPSLEEAARDLGASPWQTFRRVTLPLIAPGIL 189
glnP PRK09494
glutamine ABC transporter permease protein; Reviewed
 14-145 1.60e-05

glutamine ABC transporter permease protein; Reviewed


Pssm-ID: 181907 [Multi-domain]  Cd Length: 219  Bit Score: 44.28  E-value: 1.60e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446390146  14 ALYETLYMVSIALFLGAVIGIPLGVLLVITRKQGIWPNIVIHQVLnplINILRSLPfIILLIAIVPFTKLVVGTSI---G 90
Cdd:PRK09494  14 LLLEGAKMTLWISVLGLAGGLVIGLLAGFARAYGGWIANHIALVF---IELIRGTP-IVVQVMFIYFALPMAFNDLridP 89

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 446390146  91 TTAAIVPLTVYVAPYIARLVENSLLEVDEGIIEAAKAMGASPLQIIRYFLIPEAL 145
Cdd:PRK09494  90 FTAAVVTIMINSGAYIAEITRGAVLSIHKGFREAGLALGLSRRETLRYVIGPLAL 144
PstC COG0573
ABC-type phosphate transport system, permease component [Inorganic ion transport and ...
 27-156 2.25e-05

ABC-type phosphate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440338 [Multi-domain]  Cd Length: 303  Bit Score: 44.31  E-value: 2.25e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446390146  27 FLGAVIGIPLGVLLVI------TRKqgiwpnivIHQVLNPLINILRSLPFIIL----LIAIVPFTKLVVGTSIGT----T 92
Cdd:COG0573   87 LIALLIAVPLGLGIAIflseyaPPR--------LRRILKPAIELLAGIPSVVYgfwgLFVLVPLLRDLFPWPPSGfsllT 158

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446390146  93 AAIVpLTVYVAPYIARLVENSLLEVDEGIIEAAKAMGASPLQIIRYFLIPEAL----GSLVLAITTAI 156
Cdd:COG0573  159 AGIV-LAIMILPTITSLSRDALRAVPRSLREAALALGATRWETIRKVVLPAARsgiiAAVILGLGRAL 225
PRK10952 PRK10952
proline/glycine betaine ABC transporter permease ProW;
18-145 3.08e-05

proline/glycine betaine ABC transporter permease ProW;


Pssm-ID: 236805  Cd Length: 355  Bit Score: 43.93  E-value: 3.08e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446390146  18 TLYMVSIALFLGAVIGIPLGVLLVITRKQGiwpnivihQVLNPLINILRSLPFIILLIAIVpftkLVVGtsIGTTAAIVP 97
Cdd:PRK10952 149 TLALVLTALLFCIVIGLPLGIWLARSPRAA--------KIIRPLLDAMQTTPAFVYLVPIV----MLFG--IGNVPGVVV 214

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*...
gi 446390146  98 LTVYVAPYIARLVENSLLEVDEGIIEAAKAMGASPLQIIRYFLIPEAL 145
Cdd:PRK10952 215 TIIFALPPIVRLTILGINQVPADLIEASRSFGASPRQMLFKVQLPLAM 262
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
2-151 3.71e-05

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 44.00  E-value: 3.71e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446390146   2 FGSDLDSAQLVQALYETLYMVSIALFLGAVIGIPLGVLLVITRKQGIwpnivihQVLNPLINILRSLPFIILLIAIVPFT 81
Cdd:COG1178  327 YRFVLLDPSLLRALLNSLLLALLAALLAVLLALLLAYLVRRRRGRLA-------RLLDRLAMLPYAVPGIVLGLGLLLLF 399

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446390146  82 KLVVGTSIGTTAAIVPLtVYVA---PYIARLVENSLLEVDEGIIEAAKAMGASPLQIIRYFLIPEALGSLVLA 151
Cdd:COG1178  400 NRPLPLLLYGTLAILVL-AYVVrflPFALRSLEAALAQIDPSLEEAARSLGASPLRTLRRVTLPLLRPGLLAA 471
DppB COG0601
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 8-161 1.17e-04

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440366 [Multi-domain]  Cd Length: 314  Bit Score: 41.98  E-value: 1.17e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446390146   8 SAQLVQALYETLYMVSIALFLGAVIGIPLGVLlvitrkQGIWPNIVIHQVLNPLINILRSLP---FIILLIAI------- 77
Cdd:COG0601   88 SDLIAERLPVTLELALLALLLALLIGIPLGIL------AALRRGSWLDRLITVLALLGISIPsfwLGLLLILLfavklgw 161

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446390146  78 ------VPFTKLVVGTSIGTTAAIVPLTVYVAPYIARLVENSLLEV-DEGIIEAAKAMGASPLQIIRYFLIPEALGSLVL 150
Cdd:COG0601  162 lpvsgrVSPWEDFLDALRHLILPALTLALGSLAGIARLTRSSMLEVlGQDYVRTARAKGLSERRVLLRHALRNALIPVVT 241

                        170
                 ....*....|.
gi 446390146 151 AITTAIIGLIG 161
Cdd:COG0601  242 VLGLQLGGLLG 252
ABC_perm1 NF038017
ABC transporter permease; Proteins of this family are the permease subunit of an ABC ...
 18-155 1.25e-04

ABC transporter permease; Proteins of this family are the permease subunit of an ABC transporter complex, which may be involved in tungstate uptake.


Pssm-ID: 411610 [Multi-domain]  Cd Length: 184  Bit Score: 41.38  E-value: 1.25e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446390146  18 TLYMVSIALFLGAVIGIPLGVLLVITRKQGiwpniviHQVLNPLINILRSLP-------FIILLIAIVPFTKLvvGTSIG 90
Cdd:NF038017   1 SLRVSGTATLIAALIGIPLGALLALRRFPG-------RRLVISLLNTLMGLPpvvvgliVYLLLSRSGPLGFL--GLLYT 71

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446390146  91 TTAAIVPLTVYVAPYIARLVENSLLEVDEGIIEAAKAMGASPLQIIRyFLIPEALGSLVLAITTA 155
Cdd:NF038017  72 PTAMIIAQAVLALPIVAGLTLAAVQGLDPELRLQILSLGATRWQALW-TLLKEARFALLAAVLAG 135
PRK10160 PRK10160
taurine ABC transporter permease TauC;
9-145 4.21e-04

taurine ABC transporter permease TauC;


Pssm-ID: 182276  Cd Length: 275  Bit Score: 40.15  E-value: 4.21e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446390146   9 AQLVQALYETLYMVSIALFLGAVIGIPLGVLLvitrkqGIWPNivIHQVLNPLINILRSLPfiilLIAIVPFtkLVVGTS 88
Cdd:PRK10160  74 ATLWQHLAASLTRIVLALLAAVVIGIPVGIAM------GLSPT--VRGILDPLIELYRPVP----PLAYLPL--MVIWFG 139

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 446390146  89 IGTTAAIVPLTVYVAPYIARLVENSLLEVDEGIIEAAKAMGASPLQIIRYFLIPEAL 145
Cdd:PRK10160 140 IGETSKILLIYLAIFAPVAMSALAGVKSAQQVRIRAAQSLGASRAQVLWFVILPGAL 196
PRK15107 PRK15107
glutamate/aspartate ABC transporter permease GltK;
11-163 2.15e-03

glutamate/aspartate ABC transporter permease GltK;


Pssm-ID: 185062 [Multi-domain]  Cd Length: 224  Bit Score: 37.89  E-value: 2.15e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446390146  11 LVQALYETLYMVSIALflgaVIGIPLGVLLVITRKQGIWPnivIHQVLNPLINILRSLPFIILLI---AIVP-FTKLVVG 86
Cdd:PRK15107  16 LLDGLVITLKITVTAV----VIGILWGTILAVMRLSSFKP---VAWFAKAYVNVFRSIPLVMVLLwfyLIVPgFLQNVLG 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446390146  87 ----TSIGTTAAIVPLTVYVAPYIARLVENSLLEVDEGIIEAAKAMGASPLQIIRYFLIPEALGSLVLAITTAIIGLIGS 162
Cdd:PRK15107  89 lspkTDIRLISAMVAFSMFEAAYYSEIIRAGIQSISRGQSSAALALGMTHWQSMKLIILPQAFRAMVPLLLTQGIVLFQD 168


                 .
gi 446390146 163 T 163
Cdd:PRK15107 169 T 169
PRK15050 PRK15050
2-aminoethylphosphonate transport system permease PhnU; Provisional
 99-154 3.95e-03

2-aminoethylphosphonate transport system permease PhnU; Provisional


Pssm-ID: 237888 [Multi-domain]  Cd Length: 296  Bit Score: 37.29  E-value: 3.95e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446390146  99 TVYVAPYIARLVENSLLEVDEGIIEAAKAMGASPLQIIRYFLIPEAL------GSLVLAITT 154
Cdd:PRK15050 169 ITFYTPFVVRPLLAAFAQLDARQLEAAASLGASPWRVARRVILPEAWpalaagGSLCLLLTL 230
PRK15100 PRK15100
cystine ABC transporter permease;
6-163 7.17e-03

cystine ABC transporter permease;


Pssm-ID: 185055 [Multi-domain]  Cd Length: 220  Bit Score: 36.27  E-value: 7.17e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446390146   6 LDSAQ-LVQALYETLYMVSIALFLGAVigipLGVLLVITRKQGIWPNIVIHQVLnplINILRSLPFIILLIAIVpFTKLV 84
Cdd:PRK15100   9 IDSAPfLLKGAGYTLQLSIGGMFFGLL----LGFILALMRLSPIWPVRWLARFY---VSIFRGTPLIAQLFMIY-YGLPQ 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446390146  85 VGTSIGT-TAAIVPLTVYVAPYIARLVENSLLEVDEGIIEAAKAMGASPLQIIRYFLIPEALGSLVLAITTAIIGLIGST 163
Cdd:PRK15100  81 FGIELDPiPAAMIGLSLNTAAYAAETLRAAISSIDKGQWEAAASIGMTRWQTLRRAILPQAARTALPPLSNSFISLVKDT 160
PRK09881 PRK09881
D,D-dipeptide ABC transporter permease;
3-160 7.49e-03

D,D-dipeptide ABC transporter permease;


Pssm-ID: 182131 [Multi-domain]  Cd Length: 296  Bit Score: 36.72  E-value: 7.49e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446390146   3 GSDLDSAQLV---QALYETLYMVSIALFLGAVIGIPLGVLlvitrkQGIWPNIVIHqvlnpLINILRSLPFIILLIAIVP 79
Cdd:PRK09881  82 GRDLFSRVLVgsqQSILAGLVVVAIAGMIGSLLGCLSGVL------GGRADAIIMR-----IMDIMLSIPSLVLTMALAA 150

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446390146  80 ftklVVGTSIGTtaAIVPLTVYVAPYIARLVENSLLEVDE-GIIEAAKAMGASPLQIIRYFLIPEALGSLVLAITTAIIG 158
Cdd:PRK09881 151 ----ALGPSLFN--AMLAIAIVRIPFYVRLARGQALVVRQyTYVQAAKTFGASRWHLISWHILRNSLPPLIVQASLDIGS 224


                 ..
gi 446390146 159 LI 160
Cdd:PRK09881 225 AI 226
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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