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Conserved domains on  [gi|446381739|ref|WP_000459594|]
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MULTISPECIES: Sec-independent protein translocase protein TatB [Enterobacteriaceae]

Protein Classification

tatB family protein( domain architecture ID 13266552)

tatB family protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
tatB TIGR01410
twin arginine-targeting protein translocase TatB; This model represents the TatB protein of a ...
 2-81 9.61e-37

twin arginine-targeting protein translocase TatB; This model represents the TatB protein of a Sec-independent system for transporting folded proteins, often with a bound redox cofactor, across the bacterial inner membrane. TatC is the multiple membrane spanning component. TatB, like the related TatA/E proteins, appears to span the membrane one time. The tat system recognizes proteins with an elongated signal sequence containing a conserved R-R in a motif approximated by RRxFLK N-terminal to the transmembrane helix. TIGRFAMs model TIGR01409 describes this twin-Arg signal sequence. A similar system, termed Delta-pH-dependent transport, operates on chloroplast-encoded proteins. [Protein fate, Protein and peptide secretion and trafficking]


:

Pssm-ID: 130477 [Multi-domain]  Cd Length: 80  Bit Score: 121.65  E-value: 9.61e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446381739    2 FDIGFSELLLVFIIGLVVLGPQRLPVAVKTVAGWIRALRSLATTVQNELTQELKLQEFQDSLKKVEKASLTNLTPELKAS 81
Cdd:TIGR01410   1 FDIGFSELLLIAVVALVVLGPERLPVAIRTVGGFVRALRGMASDVKNELDEELKLQELDDQLKKAQQARFLNLTAELKDS 80
PRK04654 super family cl31366
sec-independent translocase; Provisional
 1-171 2.04e-18

sec-independent translocase; Provisional


The actual alignment was detected with superfamily member PRK04654:

Pssm-ID: 135173 [Multi-domain]  Cd Length: 214  Bit Score: 78.70  E-value: 2.04e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446381739   1 MFDIGFSELLLVFIIGLVVLGPQRLPVAVKTVAGWIRALRSLATTVQNELTQELKLQEFQDSLKKVEkASLTNLTPELKA 80
Cdd:PRK04654   1 MFDIGVGELTLIAVVALVVLGPERLPKAARFAGLWVRRARMQWDSVKQELERELEAEELKRSLQDVQ-ASLREAEDQLRN 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446381739  81 SMDELRQAAESMkrsyvaNDPEKASDEAHTIHNPVVKDNEAAHEG------VTPAAAQTQASSPEQKPETTPEPVV---K 151
Cdd:PRK04654  80 TQQQVEQGARAL------HDDVSRDIDIRTSATPVATPLELAHADlsasaqVDAAAGAEPGAGQAHTPVPAPAPVIaqaQ 153

                        170       180
                 ....*....|....*....|
gi 446381739 152 PAADAEPKTAAPSPSSSDKP 171
Cdd:PRK04654 154 PIAPAPHQTLVPAPHDTIVP 173
 
Name Accession Description Interval E-value
tatB TIGR01410
twin arginine-targeting protein translocase TatB; This model represents the TatB protein of a ...
 2-81 9.61e-37

twin arginine-targeting protein translocase TatB; This model represents the TatB protein of a Sec-independent system for transporting folded proteins, often with a bound redox cofactor, across the bacterial inner membrane. TatC is the multiple membrane spanning component. TatB, like the related TatA/E proteins, appears to span the membrane one time. The tat system recognizes proteins with an elongated signal sequence containing a conserved R-R in a motif approximated by RRxFLK N-terminal to the transmembrane helix. TIGRFAMs model TIGR01409 describes this twin-Arg signal sequence. A similar system, termed Delta-pH-dependent transport, operates on chloroplast-encoded proteins. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 130477 [Multi-domain]  Cd Length: 80  Bit Score: 121.65  E-value: 9.61e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446381739    2 FDIGFSELLLVFIIGLVVLGPQRLPVAVKTVAGWIRALRSLATTVQNELTQELKLQEFQDSLKKVEKASLTNLTPELKAS 81
Cdd:TIGR01410   1 FDIGFSELLLIAVVALVVLGPERLPVAIRTVGGFVRALRGMASDVKNELDEELKLQELDDQLKKAQQARFLNLTAELKDS 80
TatA COG1826
Twin-arginine protein secretion pathway components TatA and TatB [Intracellular trafficking, ...
 1-69 2.72e-20

Twin-arginine protein secretion pathway components TatA and TatB [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 441431 [Multi-domain]  Cd Length: 72  Bit Score: 79.59  E-value: 2.72e-20
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446381739   1 MFDIGFSELLLVFIIGLVVLGPQRLPVAVKTVAGWIRALRSLATTVQNELTQELKLQEFQDSLKKVEKA 69
Cdd:COG1826    1 MFGIGFWELLIILVVALLVFGPKKLPELARSLGKAIREFKKAANEVKEELDEELKEEELRKSEKEAEEL 69
PRK04654 PRK04654
sec-independent translocase; Provisional
 1-171 2.04e-18

sec-independent translocase; Provisional


Pssm-ID: 135173 [Multi-domain]  Cd Length: 214  Bit Score: 78.70  E-value: 2.04e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446381739   1 MFDIGFSELLLVFIIGLVVLGPQRLPVAVKTVAGWIRALRSLATTVQNELTQELKLQEFQDSLKKVEkASLTNLTPELKA 80
Cdd:PRK04654   1 MFDIGVGELTLIAVVALVVLGPERLPKAARFAGLWVRRARMQWDSVKQELERELEAEELKRSLQDVQ-ASLREAEDQLRN 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446381739  81 SMDELRQAAESMkrsyvaNDPEKASDEAHTIHNPVVKDNEAAHEG------VTPAAAQTQASSPEQKPETTPEPVV---K 151
Cdd:PRK04654  80 TQQQVEQGARAL------HDDVSRDIDIRTSATPVATPLELAHADlsasaqVDAAAGAEPGAGQAHTPVPAPAPVIaqaQ 153

                        170       180
                 ....*....|....*....|
gi 446381739 152 PAADAEPKTAAPSPSSSDKP 171
Cdd:PRK04654 154 PIAPAPHQTLVPAPHDTIVP 173
PRK01371 PRK01371
Sec-independent protein translocase protein TatB;
1-61 1.19e-09

Sec-independent protein translocase protein TatB;


Pssm-ID: 179287 [Multi-domain]  Cd Length: 137  Bit Score: 53.56  E-value: 1.19e-09
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446381739   1 MFDIGFSELLLVFIIGLVVLGPQRLPVAVKTVAGWIRALRSLATTVQNELTQELKlQEFQD 61
Cdd:PRK01371   1 MFGIGPGELVVLVVLAVLVFGPDKLPKAARDAGRTLRQLREMANNARNDLRSELG-PEFAD 60
TatA_B_E pfam02416
mttA/Hcf106 family; Members of this protein family are involved in a sec independent ...
 4-53 6.57e-04

mttA/Hcf106 family; Members of this protein family are involved in a sec independent translocation mechanism. This pathway has been called the DeltapH pathway in chloroplasts. Members of this family in E.coli are involved in export of redox proteins with a "twin arginine" leader motif.


Pssm-ID: 426762  Cd Length: 53  Bit Score: 36.13  E-value: 6.57e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 446381739    4 IGFSELLLVFIIGLVVLGPQRLPVAVKTVAGWIRALRSLATTVQNELTQE 53
Cdd:pfam02416   1 LGIPELLIILVVALLLFGPKKLPELGRALGKTLREFKKATKELEEEDEKE 50
 
Name Accession Description Interval E-value
tatB TIGR01410
twin arginine-targeting protein translocase TatB; This model represents the TatB protein of a ...
 2-81 9.61e-37

twin arginine-targeting protein translocase TatB; This model represents the TatB protein of a Sec-independent system for transporting folded proteins, often with a bound redox cofactor, across the bacterial inner membrane. TatC is the multiple membrane spanning component. TatB, like the related TatA/E proteins, appears to span the membrane one time. The tat system recognizes proteins with an elongated signal sequence containing a conserved R-R in a motif approximated by RRxFLK N-terminal to the transmembrane helix. TIGRFAMs model TIGR01409 describes this twin-Arg signal sequence. A similar system, termed Delta-pH-dependent transport, operates on chloroplast-encoded proteins. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 130477 [Multi-domain]  Cd Length: 80  Bit Score: 121.65  E-value: 9.61e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446381739    2 FDIGFSELLLVFIIGLVVLGPQRLPVAVKTVAGWIRALRSLATTVQNELTQELKLQEFQDSLKKVEKASLTNLTPELKAS 81
Cdd:TIGR01410   1 FDIGFSELLLIAVVALVVLGPERLPVAIRTVGGFVRALRGMASDVKNELDEELKLQELDDQLKKAQQARFLNLTAELKDS 80
TatA COG1826
Twin-arginine protein secretion pathway components TatA and TatB [Intracellular trafficking, ...
 1-69 2.72e-20

Twin-arginine protein secretion pathway components TatA and TatB [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 441431 [Multi-domain]  Cd Length: 72  Bit Score: 79.59  E-value: 2.72e-20
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446381739   1 MFDIGFSELLLVFIIGLVVLGPQRLPVAVKTVAGWIRALRSLATTVQNELTQELKLQEFQDSLKKVEKA 69
Cdd:COG1826    1 MFGIGFWELLIILVVALLVFGPKKLPELARSLGKAIREFKKAANEVKEELDEELKEEELRKSEKEAEEL 69
PRK04654 PRK04654
sec-independent translocase; Provisional
 1-171 2.04e-18

sec-independent translocase; Provisional


Pssm-ID: 135173 [Multi-domain]  Cd Length: 214  Bit Score: 78.70  E-value: 2.04e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446381739   1 MFDIGFSELLLVFIIGLVVLGPQRLPVAVKTVAGWIRALRSLATTVQNELTQELKLQEFQDSLKKVEkASLTNLTPELKA 80
Cdd:PRK04654   1 MFDIGVGELTLIAVVALVVLGPERLPKAARFAGLWVRRARMQWDSVKQELERELEAEELKRSLQDVQ-ASLREAEDQLRN 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446381739  81 SMDELRQAAESMkrsyvaNDPEKASDEAHTIHNPVVKDNEAAHEG------VTPAAAQTQASSPEQKPETTPEPVV---K 151
Cdd:PRK04654  80 TQQQVEQGARAL------HDDVSRDIDIRTSATPVATPLELAHADlsasaqVDAAAGAEPGAGQAHTPVPAPAPVIaqaQ 153

                        170       180
                 ....*....|....*....|
gi 446381739 152 PAADAEPKTAAPSPSSSDKP 171
Cdd:PRK04654 154 PIAPAPHQTLVPAPHDTIVP 173
PRK01371 PRK01371
Sec-independent protein translocase protein TatB;
1-61 1.19e-09

Sec-independent protein translocase protein TatB;


Pssm-ID: 179287 [Multi-domain]  Cd Length: 137  Bit Score: 53.56  E-value: 1.19e-09
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446381739   1 MFDIGFSELLLVFIIGLVVLGPQRLPVAVKTVAGWIRALRSLATTVQNELTQELKlQEFQD 61
Cdd:PRK01371   1 MFGIGPGELVVLVVLAVLVFGPDKLPKAARDAGRTLRQLREMANNARNDLRSELG-PEFAD 60
tatA PRK14858
twin arginine translocase protein A; Provisional
 1-104 5.81e-09

twin arginine translocase protein A; Provisional


Pssm-ID: 184860  Cd Length: 108  Bit Score: 51.02  E-value: 5.81e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446381739   1 MFDIGFSELLLVFIIGLVVLGPQRLPVAVKTVAGWIRALRSLATTVQNELTQELKLQEFQDSLKKVEKASLTNLTPELKA 80
Cdd:PRK14858   1 MFGIGMPELIVILVIALIVIGPQKLPDLARSLGRGLAEFKKATDDFKQSMQEESRTAEEKEKAEKLAETKKEAEAPEAKA 80

                         90       100
                 ....*....|....*....|....
gi 446381739  81 SMDELRQAAESMKRSYVANDPEKA 104
Cdd:PRK14858  81 EEDQAPKPKGAGEPPATVASKAGD 104
tatB PRK00182
Sec-independent protein translocase subunit TatB;
1-154 9.94e-09

Sec-independent protein translocase subunit TatB;


Pssm-ID: 234681  Cd Length: 160  Bit Score: 51.75  E-value: 9.94e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446381739   1 MF-DIGFSELLLVFIIGLVVLGPQRLPVAVKTVAGWIRALRSLATTVQNELTQEL--KLQEFQDSLKKVekASLTNLTPE 77
Cdd:PRK00182   1 MFsSVGWGEILLLLIVGLIVIGPERLPRLIEDVRAALLAARTAINNAKQQLDGDFgeEFDEFRKPLNQI--ASYRRMGPK 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446381739  78 ---LKASMDElrqaAESMKRSYvanDPEK--ASDEAHTIHNPVVKDNEAAHEGVTPAAAQTQASSPEQKPETtpePVVKP 152
Cdd:PRK00182  79 taiTKALFDG----DDSFLDDF---DPKKimADGTEGEAQRQQQASAGRADNNANVVTRPADGSQPRSSQND---PKGGP 148


                 ..
gi 446381739 153 AA 154
Cdd:PRK00182 149 PY 150
tatA PRK14857
TatA/E family twin arginine-targeting protein translocase;
2-91 1.29e-04

TatA/E family twin arginine-targeting protein translocase;


Pssm-ID: 184859  Cd Length: 90  Bit Score: 38.93  E-value: 1.29e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446381739   2 FDIGFSELLLVFIIGLVVLGPQRLPVAVKTVAGWIRALRSLATTVQNELTQELKLQEfqdSLKKVEKASLTNLTPELKAS 81
Cdd:PRK14857   4 FGIGLPEMAVILVIALLVFGPKKLPEIGRSLGKTLKGFQEASKEFENEIKREMAEPE---QEVKAPAELESNQTNEANQE 80

                         90
                 ....*....|
gi 446381739  82 MDELRQAAES 91
Cdd:PRK14857  81 QVDAENSPES 90
tatA PRK14860
twin arginine translocase protein A; Provisional
 1-40 2.30e-04

twin arginine translocase protein A; Provisional


Pssm-ID: 184862  Cd Length: 64  Bit Score: 37.79  E-value: 2.30e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|
gi 446381739   1 MFDIGFSELLLVFIIGLVVLGPQRLPVAVKTVAGWIRALR 40
Cdd:PRK14860   1 MFGFGMPELIVILVIALVVFGPAKLPQLGQALGGAIRNFK 40
TatA_B_E pfam02416
mttA/Hcf106 family; Members of this protein family are involved in a sec independent ...
 4-53 6.57e-04

mttA/Hcf106 family; Members of this protein family are involved in a sec independent translocation mechanism. This pathway has been called the DeltapH pathway in chloroplasts. Members of this family in E.coli are involved in export of redox proteins with a "twin arginine" leader motif.


Pssm-ID: 426762  Cd Length: 53  Bit Score: 36.13  E-value: 6.57e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 446381739    4 IGFSELLLVFIIGLVVLGPQRLPVAVKTVAGWIRALRSLATTVQNELTQE 53
Cdd:pfam02416   1 LGIPELLIILVVALLLFGPKKLPELGRALGKTLREFKKATKELEEEDEKE 50
PHA03269 PHA03269
envelope glycoprotein C; Provisional
 75-171 6.61e-04

envelope glycoprotein C; Provisional


Pssm-ID: 165527 [Multi-domain]  Cd Length: 566  Bit Score: 39.33  E-value: 6.61e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446381739  75 TPELKASMDELRQ--AAESMKRSYVANDPEKASDEAHTIH-NPVVKDNEAAHEGVTPAAAQTQASSPEQKPETTPEPVVK 151
Cdd:PHA03269  28 IPELHTSAATQKPdpAPAPHQAASRAPDPAVAPTSAASRKpDLAQAPTPAASEKFDPAPAPHQAASRAPDPAVAPQLAAA 107

                         90       100
                 ....*....|....*....|...
gi 446381739 152 PAADA-EPKTAAPS--PSSSDKP 171
Cdd:PHA03269 108 PKPDAaEAFTSAAQahEAPADAG 130
tatA PRK14859
twin arginine translocase protein A; Provisional
 1-26 1.31e-03

twin arginine translocase protein A; Provisional


Pssm-ID: 184861  Cd Length: 63  Bit Score: 35.47  E-value: 1.31e-03
                         10        20
                 ....*....|....*....|....*.
gi 446381739   1 MFDIGFSELLLVFIIGLVVLGPQRLP 26
Cdd:PRK14859   1 MFGIGMPELIVILVIVLIVFGAGKLP 26
tatA PRK14861
twin arginine translocase protein A; Provisional
 1-26 5.30e-03

twin arginine translocase protein A; Provisional


Pssm-ID: 237837  Cd Length: 61  Bit Score: 33.79  E-value: 5.30e-03
                         10        20
                 ....*....|....*....|....*.
gi 446381739   1 MFDIGFSELLLVFIIGLVVLGPQRLP 26
Cdd:PRK14861   2 FSNIGFPGLILILVVALIIFGPKKLP 27
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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