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Conserved domains on  [gi|446311655|ref|WP_000389510|]
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MULTISPECIES: tetratricopeptide repeat protein [Staphylococcus]

Protein Classification

tetratricopeptide repeat protein( domain architecture ID 18770923)

tetratricopeptide repeat (TPR) protein may adopt a right-handed helical structure with an amphipathic channel and may function as an interaction scaffold in the formation of multi-protein complexes

CATH:  1.25.40.10
Gene Ontology:  GO:0005515
PubMed:  30708253|22404999|21153002
SCOP:  4001344

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 101-359 5.00e-22

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 94.80  E-value: 5.00e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446311655 101 LEADLYQQINMMEVAIAKLQEALELEPNDPIIHFALAEMLYYDGQYLRATSEYETVLETGEYQVNgvnLFSRMADCSLQS 180
Cdd:COG2956   13 FKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAE---ALLELAQDYLKA 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446311655 181 GNYSDAIRLYDEINEDEMTSEDYLKK-AISYDKNDITQEAIKIMTTLLSKDPDYIQGYLYLQSLYENEKNYPDAIETGKE 259
Cdd:COG2956   90 GLLDRAEELLEKLLELDPDDAEALRLlAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEK 169

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446311655 260 GLRLSQFYKELMYTTGCLEIEHGDANEGVLLLRQALEVDNAYQEPLLILSDLYRNEEDYEAIIELLTYVDEEDLDPTFMW 339
Cdd:COG2956  170 ALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPSDDLLL 249

                        250       260
                 ....*....|....*....|
gi 446311655 340 HLAFAYGQEERDKEAQHFFE 359
Cdd:COG2956  250 ALADLLERKEGLEAALALLE 269
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 33-158 1.80e-07

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


:

Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 50.19  E-value: 1.80e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446311655  33 DALFILGETLYNFGLMPQGLEVFRVLYHKYPDESELLIYFIEGLMSENQTDEALEYLSY---VEP-SPEKLMLEADLYQQ 108
Cdd:COG4783    5 EALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEaleLDPdEPEARLNLGLALLK 84

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|
gi 446311655 109 INMMEVAIAKLQEALELEPNDPIIHFALAEMLYYDGQYLRATSEYETVLE 158
Cdd:COG4783   85 AGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALE 134
 
Name Accession Description Interval E-value
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 101-359 5.00e-22

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 94.80  E-value: 5.00e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446311655 101 LEADLYQQINMMEVAIAKLQEALELEPNDPIIHFALAEMLYYDGQYLRATSEYETVLETGEYQVNgvnLFSRMADCSLQS 180
Cdd:COG2956   13 FKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAE---ALLELAQDYLKA 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446311655 181 GNYSDAIRLYDEINEDEMTSEDYLKK-AISYDKNDITQEAIKIMTTLLSKDPDYIQGYLYLQSLYENEKNYPDAIETGKE 259
Cdd:COG2956   90 GLLDRAEELLEKLLELDPDDAEALRLlAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEK 169

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446311655 260 GLRLSQFYKELMYTTGCLEIEHGDANEGVLLLRQALEVDNAYQEPLLILSDLYRNEEDYEAIIELLTYVDEEDLDPTFMW 339
Cdd:COG2956  170 ALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPSDDLLL 249

                        250       260
                 ....*....|....*....|
gi 446311655 340 HLAFAYGQEERDKEAQHFFE 359
Cdd:COG2956  250 ALADLLERKEGLEAALALLE 269
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 58-403 8.17e-11

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 63.95  E-value: 8.17e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446311655   58 LYHKYPDESELLIYFIEGLMSENQTDEAL----EYLSYVEPSPEKLMLEADLYQQINMMEVAIAKLQEALELEPNDPIIH 133
Cdd:TIGR02917 559 AAELNPQEIEPALALAQYYLGKGQLKKALailnEAADAAPDSPEAWLMLGRAQLAAGDLNKAVSSFKKLLALQPDSALAL 638

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446311655  134 FALAEMLYYDGQYLRATSEYETVLEtgeyqvngvnlfsrmadcsLQSGNYSDAIRLYDEINEDEMTSEdylkkaisydkn 213
Cdd:TIGR02917 639 LLLADAYAVMKNYAKAITSLKRALE-------------------LKPDNTEAQIGLAQLLLAAKRTES------------ 687

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446311655  214 ditqeAIKIMTTLLSKDPDYIQGYLYLQSLYENEKNYPDAIETGKEGLRLSQFYKELMYTTGCLeIEHGDANEGVLLLRQ 293
Cdd:TIGR02917 688 -----AKKIAKSLQKQHPKAALGFELEGDLYLRQKDYPAAIQAYRKALKRAPSSQNAIKLHRAL-LASGNTAEAVKTLEA 761

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446311655  294 ALEVDNAYQEPLLILSDLYRNEEDY-EAIIELLTYVDEEDLDPTFMWHLAFAYGQEeRDKEAQHFFELAYPTMKTNIDFM 372
Cdd:TIGR02917 762 WLKTHPNDAVLRTALAELYLAQKDYdKAIKHYQTVVKKAPDNAVVLNNLAWLYLEL-KDPRALEYAERALKLAPNIPAIL 840

                         330       340       350
                  ....*....|....*....|....*....|.
gi 446311655  373 SDYYFYLTEIGQKEQAITILNQLLELEPSNE 403
Cdd:TIGR02917 841 DTLGWLLVEKGEADRALPLLRKAVNIAPEAA 871
PRK11788 PRK11788
tetratricopeptide repeat protein; Provisional
 227-401 1.67e-09

tetratricopeptide repeat protein; Provisional


Pssm-ID: 236983 [Multi-domain]  Cd Length: 389  Bit Score: 59.05  E-value: 1.67e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446311655 227 LSKDPDYIQGYL-YLQSLYENEKNYPDAIETGKE---------GLRLSQFYKELmyttGCLEIEHGDANEGVLLLRQALE 296
Cdd:PRK11788 133 LVDEGDFAEGALqQLLEIYQQEKDWQKAIDVAERleklggdslRVEIAHFYCEL----AQQALARGDLDAARALLKKALA 208

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446311655 297 VDNAYQEPLLILSDLYRNEEDYEAIIELLTYVdeEDLDPTFMWH----LAFAYGQEERDKEAQHFFELAYPTmKTNIDFM 372
Cdd:PRK11788 209 ADPQCVRASILLGDLALAQGDYAAAIEALERV--EEQDPEYLSEvlpkLMECYQALGDEAEGLEFLRRALEE-YPGADLL 285

                        170       180
                 ....*....|....*....|....*....
gi 446311655 373 SDYYFYLTEIGQKEQAITILNQLLELEPS 401
Cdd:PRK11788 286 LALAQLLEEQEGPEAAQALLREQLRRHPS 314
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 33-158 1.80e-07

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 50.19  E-value: 1.80e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446311655  33 DALFILGETLYNFGLMPQGLEVFRVLYHKYPDESELLIYFIEGLMSENQTDEALEYLSY---VEP-SPEKLMLEADLYQQ 108
Cdd:COG4783    5 EALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEaleLDPdEPEARLNLGLALLK 84

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|
gi 446311655 109 INMMEVAIAKLQEALELEPNDPIIHFALAEMLYYDGQYLRATSEYETVLE 158
Cdd:COG4783   85 AGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALE 134
PRK15179 PRK15179
Vi polysaccharide biosynthesis protein TviE; Provisional
 36-158 1.44e-05

Vi polysaccharide biosynthesis protein TviE; Provisional


Pssm-ID: 185101 [Multi-domain]  Cd Length: 694  Bit Score: 47.34  E-value: 1.44e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446311655  36 FILGETLYNFGLMPQGLEVFRVLYHKYPDESELLIYFIEGLMSENQTDEALE----YLSYVEPSPEKLMLEADLYQQINM 111
Cdd:PRK15179  90 VLVARALEAAHRSDEGLAVWRGIHQRFPDSSEAFILMLRGVKRQQGIEAGRAeielYFSGGSSSAREILLEAKSWDEIGQ 169

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*..
gi 446311655 112 MEVAIAKLQEALELEPNDPIIHFALAEMLYYDGQYLRATSEYETVLE 158
Cdd:PRK15179 170 SEQADACFERLSRQHPEFENGYVGWAQSLTRRGALWRARDVLQAGLD 216
 
Name Accession Description Interval E-value
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 101-359 5.00e-22

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 94.80  E-value: 5.00e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446311655 101 LEADLYQQINMMEVAIAKLQEALELEPNDPIIHFALAEMLYYDGQYLRATSEYETVLETGEYQVNgvnLFSRMADCSLQS 180
Cdd:COG2956   13 FKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAE---ALLELAQDYLKA 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446311655 181 GNYSDAIRLYDEINEDEMTSEDYLKK-AISYDKNDITQEAIKIMTTLLSKDPDYIQGYLYLQSLYENEKNYPDAIETGKE 259
Cdd:COG2956   90 GLLDRAEELLEKLLELDPDDAEALRLlAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEK 169

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446311655 260 GLRLSQFYKELMYTTGCLEIEHGDANEGVLLLRQALEVDNAYQEPLLILSDLYRNEEDYEAIIELLTYVDEEDLDPTFMW 339
Cdd:COG2956  170 ALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPSDDLLL 249

                        250       260
                 ....*....|....*....|
gi 446311655 340 HLAFAYGQEERDKEAQHFFE 359
Cdd:COG2956  250 ALADLLERKEGLEAALALLE 269
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 71-325 9.01e-21

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 91.33  E-value: 9.01e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446311655  71 YFIEGL--MSENQTDEALEYLSYV---EPSPEKLMLE-ADLYQQINMMEVAIAKLQEALELEPNDPIIHFALAEMLYYDG 144
Cdd:COG2956   11 WYFKGLnyLLNGQPDKAIDLLEEAlelDPETVEAHLAlGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAG 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446311655 145 QYLRATSEYETVLETGEYQVNgvnLFSRMADCSLQSGNYSDAIRLYDE-INEDEMTSEDYLKKAISYDKNDITQEAIKIM 223
Cdd:COG2956   91 LLDRAEELLEKLLELDPDDAE---ALRLLAEIYEQEGDWEKAIEVLERlLKLGPENAHAYCELAELYLEQGDYDEAIEAL 167

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446311655 224 TTLLSKDPDYIQGYLYLQSLYENEKNYPDAIETGKEGLRLSQFYKELMYTTGCLEIEHGDANEGVLLLRQALEvDNAYQE 303
Cdd:COG2956  168 EKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALE-LDPSDD 246

                        250       260
                 ....*....|....*....|..
gi 446311655 304 PLLILSDLYRNEEDYEAIIELL 325
Cdd:COG2956  247 LLLALADLLERKEGLEAALALL 268
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 50-296 9.90e-15

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 74.00  E-value: 9.90e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446311655  50 QGLEVFRVLYHKYPDESELLIYFIEGLMSENQTDEALE-YLSYVEPSPEK---LMLEADLYQQINMMEVAIAKLQEALEL 125
Cdd:COG2956   26 KAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRiHQKLLERDPDRaeaLLELAQDYLKAGLLDRAEELLEKLLEL 105

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446311655 126 EPNDPIIHFALAEMLYYDGQYLRATSEYETVLETGEYQVNgvnLFSRMADCSLQSGNYSDAIRLYDE-INEDEMTSEDYL 204
Cdd:COG2956  106 DPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAH---AYCELAELYLEQGDYDEAIEALEKaLKLDPDCARALL 182

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446311655 205 KKAISYDKNDITQEAIKIMTTLLSKDPDYIQGYLYLQSLYENEKNYPDAIETGKEGLRLsQFYKELMYTTGCLEIEHGDA 284
Cdd:COG2956  183 LLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALEL-DPSDDLLLALADLLERKEGL 261

                        250
                 ....*....|..
gi 446311655 285 NEGVLLLRQALE 296
Cdd:COG2956  262 EAALALLERQLR 273
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 26-262 5.19e-14

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 71.68  E-value: 5.19e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446311655  26 AITTDNDDALFILGETLYNFGLMPQGLEVFRVLYHKYPDESELLIYFIEGLMSENQTDEALEYLSYVEPSPEK----LML 101
Cdd:COG2956   36 ELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELLEKLLELDPDdaeaLRL 115

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446311655 102 EADLYQQINMMEVAIAKLQEALELEPNDPIIHFALAEMLYYDGQYLRATSEYETVLetgEYQVNGVNLFSRMADCSLQSG 181
Cdd:COG2956  116 LAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKAL---KLDPDCARALLLLAELYLEQG 192

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446311655 182 NYSDAIRLYDEI-NEDEMTSEDYLKKAISYDKNDITQEAIKIMTTLLSKDPDYIQgYLYLQSLYENEKNYPDAIETGKEG 260
Cdd:COG2956  193 DYEEAIAALERAlEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPSDDL-LLALADLLERKEGLEAALALLERQ 271


                 ..
gi 446311655 261 LR 262
Cdd:COG2956  272 LR 273
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 203-412 2.28e-13

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 69.76  E-value: 2.28e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446311655 203 YLKKAISYDKNDITQEAIKIMTTLLSKDPDYIQGYLYLQSLYENEKNYPDAIETGKEGLRLSQFYKELMYTTGCLEIEHG 282
Cdd:COG2956   11 WYFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAG 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446311655 283 DANEGVLLLRQALEVDNAYQEPLLILSDLYRNEEDYEAIIELLTYVDEEDLDPTFMWH-LAFAYGQEERDKEAQHFFELA 361
Cdd:COG2956   91 LLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCeLAELYLEQGDYDEAIEALEKA 170

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 446311655 362 YPTMKTNIDFMSDYYFYLTEIGQKEQAITILNQLLELEPSNENWHDELSRL 412
Cdd:COG2956  171 LKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAEL 221
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 30-230 3.86e-13

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 69.37  E-value: 3.86e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446311655  30 DNDDALFILGETLYNFGLMPQGLEVFRVLYHKYPDESELLIYFIEGLMSENQTDEALEYLS-YVEPSPEK---LMLEADL 105
Cdd:COG2956   74 DRAEALLELAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLErLLKLGPENahaYCELAEL 153

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446311655 106 YQQINMMEVAIAKLQEALELEPNDPIIHFALAEMLYYDGQYLRATSEYETVLetgEYQVNGVNLFSRMADCSLQSGNYSD 185
Cdd:COG2956  154 YLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERAL---EQDPDYLPALPRLAELYEKLGDPEE 230

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 446311655 186 AIRLYDEINEDEMTSEDYLKKAISYDKNDITQEAIKIMTTLLSKD 230
Cdd:COG2956  231 ALELLRKALELDPSDDLLLALADLLERKEGLEAALALLERQLRRH 275
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
123-362 2.06e-11

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 63.49  E-value: 2.06e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446311655 123 LELEPNDPIIHFALAEMLYYDGQYLRATSEYETVLETGEyqvNGVNLFSRMADCSLQSGNYSDAIRLYDE-INEDEMTSE 201
Cdd:COG0457    1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDP---DDAEALYNLGLAYLRLGRYEEALADYEQaLELDPDDAE 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446311655 202 DYLKKAISYDKNDITQEAIKIMTTLLSKDPDYIQGYLYLQSLYENEKNYPDAIETGKEGLRLSQFYKELMYTTGCLEIEH 281
Cdd:COG0457   78 ALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKL 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446311655 282 GDANEGVLLLRQALEVDNAYQEPLLILSDLYRNEEDYEAIIELLTYVDEEDLDPTFMWHLAFAYGQEERDKEAQHFFELA 361
Cdd:COG0457  158 GRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILTLAALAELLLLALALLLALRLAA 237


                 .
gi 446311655 362 Y 362
Cdd:COG0457  238 L 238
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 58-403 8.17e-11

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 63.95  E-value: 8.17e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446311655   58 LYHKYPDESELLIYFIEGLMSENQTDEAL----EYLSYVEPSPEKLMLEADLYQQINMMEVAIAKLQEALELEPNDPIIH 133
Cdd:TIGR02917 559 AAELNPQEIEPALALAQYYLGKGQLKKALailnEAADAAPDSPEAWLMLGRAQLAAGDLNKAVSSFKKLLALQPDSALAL 638

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446311655  134 FALAEMLYYDGQYLRATSEYETVLEtgeyqvngvnlfsrmadcsLQSGNYSDAIRLYDEINEDEMTSEdylkkaisydkn 213
Cdd:TIGR02917 639 LLLADAYAVMKNYAKAITSLKRALE-------------------LKPDNTEAQIGLAQLLLAAKRTES------------ 687

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446311655  214 ditqeAIKIMTTLLSKDPDYIQGYLYLQSLYENEKNYPDAIETGKEGLRLSQFYKELMYTTGCLeIEHGDANEGVLLLRQ 293
Cdd:TIGR02917 688 -----AKKIAKSLQKQHPKAALGFELEGDLYLRQKDYPAAIQAYRKALKRAPSSQNAIKLHRAL-LASGNTAEAVKTLEA 761

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446311655  294 ALEVDNAYQEPLLILSDLYRNEEDY-EAIIELLTYVDEEDLDPTFMWHLAFAYGQEeRDKEAQHFFELAYPTMKTNIDFM 372
Cdd:TIGR02917 762 WLKTHPNDAVLRTALAELYLAQKDYdKAIKHYQTVVKKAPDNAVVLNNLAWLYLEL-KDPRALEYAERALKLAPNIPAIL 840

                         330       340       350
                  ....*....|....*....|....*....|.
gi 446311655  373 SDYYFYLTEIGQKEQAITILNQLLELEPSNE 403
Cdd:TIGR02917 841 DTLGWLLVEKGEADRALPLLRKAVNIAPEAA 871
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 13-404 5.69e-10

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 61.25  E-value: 5.69e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446311655   13 LQKLENLDSRVN--EAITTDNDDALFILGETLYNFGLMPQGLEVFRVLYHKYPDESELLIYFIEGLMSENQTDEALEYLS 90
Cdd:TIGR02917 308 LGNLEQAYQYLNqiLKYAPNSHQARRLLASIQLRLGRVDEAIATLSPALGLDPDDPAALSLLGEAYLALGDFEKAAEYLA 387

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446311655   91 YV-EPSPEKLMLEADLyQQINMM----EVAIAKLQEALELEPNDPIIHFALAEMLYYDGQYLRATSEYETVLETGEYQVN 165
Cdd:TIGR02917 388 KAtELDPENAAARTQL-GISKLSqgdpSEAIADLETAAQLDPELGRADLLLILSYLRSGQFDKALAAAKKLEKKQPDNAS 466

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446311655  166 GVNLFS----------------RMAdCSLQSGNYSDAIRL--YDEINEDEMTSEDYLKKAISYDKNDI------------ 215
Cdd:TIGR02917 467 LHNLLGaiylgkgdlakareafEKA-LSIEPDFFPAAANLarIDIQEGNPDDAIQRFEKVLTIDPKNLrailalaglylr 545

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446311655  216 ---TQEAIKIMTTLLSKDPDYIQGYLYLQSLYENEKNYPDAIETGKEGLRLSQFYKELMYTTGCLEIEHGDANEGVLLLR 292
Cdd:TIGR02917 546 tgnEEEAVAWLEKAAELNPQEIEPALALAQYYLGKGQLKKALAILNEAADAAPDSPEAWLMLGRAQLAAGDLNKAVSSFK 625

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446311655  293 QALEVDNAYQEPLLILSDLYRNEEDYEAIIELLTYVDEEDLDPT----FMWHLAFAYGQEERDKEAQHFFELAYPTMKTN 368
Cdd:TIGR02917 626 KLLALQPDSALALLLLADAYAVMKNYAKAITSLKRALELKPDNTeaqiGLAQLLLAAKRTESAKKIAKSLQKQHPKAALG 705

                         410       420       430
                  ....*....|....*....|....*....|....*.
gi 446311655  369 IDFMSDYYFyltEIGQKEQAITILNQLLELEPSNEN 404
Cdd:TIGR02917 706 FELEGDLYL---RQKDYPAAIQAYRKALKRAPSSQN 738
PRK11788 PRK11788
tetratricopeptide repeat protein; Provisional
 227-401 1.67e-09

tetratricopeptide repeat protein; Provisional


Pssm-ID: 236983 [Multi-domain]  Cd Length: 389  Bit Score: 59.05  E-value: 1.67e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446311655 227 LSKDPDYIQGYL-YLQSLYENEKNYPDAIETGKE---------GLRLSQFYKELmyttGCLEIEHGDANEGVLLLRQALE 296
Cdd:PRK11788 133 LVDEGDFAEGALqQLLEIYQQEKDWQKAIDVAERleklggdslRVEIAHFYCEL----AQQALARGDLDAARALLKKALA 208

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446311655 297 VDNAYQEPLLILSDLYRNEEDYEAIIELLTYVdeEDLDPTFMWH----LAFAYGQEERDKEAQHFFELAYPTmKTNIDFM 372
Cdd:PRK11788 209 ADPQCVRASILLGDLALAQGDYAAAIEALERV--EEQDPEYLSEvlpkLMECYQALGDEAEGLEFLRRALEE-YPGADLL 285

                        170       180
                 ....*....|....*....|....*....
gi 446311655 373 SDYYFYLTEIGQKEQAITILNQLLELEPS 401
Cdd:PRK11788 286 LALAQLLEEQEGPEAAQALLREQLRRHPS 314
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 201-325 7.50e-09

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 54.04  E-value: 7.50e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446311655 201 EDYLKKAISYDKNDITQEAIKIMTTLLSKDPDYIQGYLYLQSLYENEKNYPDAIETGKEGLRLSQFYKELMYTTGCLEIE 280
Cdd:COG4783    5 EALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLK 84

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*
gi 446311655 281 HGDANEGVLLLRQALEVDNAYQEPLLILSDLYRNEEDYEAIIELL 325
Cdd:COG4783   85 AGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAAL 129
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 95-193 1.05e-08

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 53.47  E-value: 1.05e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446311655  95 SPEKLMLEADLYQQINMMEVAIAKLQEALELEPNDPIIHFALAEMLYYDGQYLRATSEYETVLETgeyQVNGVNLFSRMA 174
Cdd:COG4235   16 DAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALAL---DPDNPEALYLLG 92

                         90
                 ....*....|....*....
gi 446311655 175 DCSLQSGNYSDAIRLYDEI 193
Cdd:COG4235   93 LAAFQQGDYAEAIAAWQKL 111
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
26-267 1.22e-08

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 55.40  E-value: 1.22e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446311655  26 AITTDNDDALFILGETLYNFGLMPQGLEVFRVLYHKYPDESELLIYFIEGLMSENQTDEALEYLSYV---EP-SPEKLML 101
Cdd:COG0457    2 ELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQAlelDPdDAEALNN 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446311655 102 EADLYQQINMMEVAIAKLQEALELEPNDPIIHFALAEMLYYDGQYLRATSEYETVLetgEYQVNGVNLFSRMADCSLQSG 181
Cdd:COG0457   82 LGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERAL---ELDPDDADALYNLGIALEKLG 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446311655 182 NYSDAIRLYDEINEDEMTSEDYLKKAISYDKNDITQEAIKIMTTLLSKDPDYIQGYLYLQSLYENEKNYPDAIETGKEGL 261
Cdd:COG0457  159 RYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILTLAALAELLLLALALLLALRLAAL 238


                 ....*.
gi 446311655 262 RLSQFY 267
Cdd:COG0457  239 ALYQYR 244
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
203-399 1.26e-08

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 55.40  E-value: 1.26e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446311655 203 YLKKAISYDKNDITQEAIKIMTTLLSKDPDYIQGYLYLQSLYENEKNYPDAIETGKEGLRLSQFYKELMYTTGCLEIEHG 282
Cdd:COG0457   11 YNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALG 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446311655 283 DANEGVLLLRQALEVDNAYQEPLLILSDLYRNEEDYEAIIELLTYVDEEDLDPTFMW-HLAFAYGQEERDKEAQHFFELA 361
Cdd:COG0457   91 RYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALyNLGIALEKLGRYEEALELLEKL 170

                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 446311655 362 YPTMKTNIDFMSDYYFYLTEIGQKEQAITILNQLLELE 399
Cdd:COG0457  171 EAAALAALLAAALGEAALALAAAEVLLALLLALEQALR 208
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 23-413 3.00e-08

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 55.86  E-value: 3.00e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446311655   23 VNEAITTD--NDDALFILGETLYNFGLMPQGLEVFRVLYHKYPDESELLIYFIEGLMSENQTDEALEYL----SYVEPSP 96
Cdd:TIGR02917 182 IDEVLTADpgNVDALLLKGDLLLSLGNIELALAAYRKAIALRPNNIAVLLALATILIEAGEFEEAEKHAdallKKAPNSP 261

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446311655   97 EKLMLEADLYQQINMMEVAIAKLQEALELEPNDPIIHFALAEMLYYDGQYLRATSEYETVLETGEYQVN----------- 165
Cdd:TIGR02917 262 LAHYLKALVDFQKKNYEDARETLQDALKSAPEYLPALLLAGASEYQLGNLEQAYQYLNQILKYAPNSHQarrllasiqlr 341

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446311655  166 ------GVNLFSRMADCS--------------LQSGNYSDAIRLYDEINEDEMTSED-YLKKAISY-DKNDITqEAIKIM 223
Cdd:TIGR02917 342 lgrvdeAIATLSPALGLDpddpaalsllgeayLALGDFEKAAEYLAKATELDPENAAaRTQLGISKlSQGDPS-EAIADL 420

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446311655  224 TTLLSKDPDYIQGYLYLQSLYENEKNYPDAIETGKEgLRLSQFYKELMYTT-GCLEIEHGDANEGVLLLRQALEVDNAYQ 302
Cdd:TIGR02917 421 ETAAQLDPELGRADLLLILSYLRSGQFDKALAAAKK-LEKKQPDNASLHNLlGAIYLGKGDLAKAREAFEKALSIEPDFF 499

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446311655  303 EPLLILSDLYRNEEDYEAIIELLTYV---DEEDLDPtfMWHLAFAYGQEERDKEAQHFFELAYPTMKTNIDFMSDYYFYL 379
Cdd:TIGR02917 500 PAAANLARIDIQEGNPDDAIQRFEKVltiDPKNLRA--ILALAGLYLRTGNEEEAVAWLEKAAELNPQEIEPALALAQYY 577

                         410       420       430
                  ....*....|....*....|....*....|....
gi 446311655  380 TEIGQKEQAITILNQLLELEPSNENWHDELSRLQ 413
Cdd:TIGR02917 578 LGKGQLKKALAILNEAADAAPDSPEAWLMLGRAQ 611
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 97-233 4.69e-08

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 51.73  E-value: 4.69e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446311655  97 EKLMLEADLYQQINMMEVAIAKLQEALELEPNDPIIHFALAEMLYYDGQYLRATSEYETVLetgEYQVNGVNLFSRMADC 176
Cdd:COG4783    5 EALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEAL---ELDPDEPEARLNLGLA 81

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 446311655 177 SLQSGNYSDAIRLYDE-INEDEMTSEDYLKKAISYDKNDITQEAIKIMTTLLSKDPDY 233
Cdd:COG4783   82 LLKAGDYDEALALLEKaLKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDPDD 139
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 236-402 1.50e-07

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 52.42  E-value: 1.50e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446311655 236 GYLYLQSLYENEKNYPDAIETGKEGLRLSQFYKELMYTTGCLEIEHGDANEGVLLLRQALEVDNAYQEPLLILSDLYRNE 315
Cdd:COG2956   10 GWYFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKA 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446311655 316 EDY-EAIIELLTYVDEEDLDPTFMWHLAFAYGQEERDKEAQHFFELAYPTMKTNIDFMSDYYFYLTEIGQKEQAITILNQ 394
Cdd:COG2956   90 GLLdRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEK 169


                 ....*...
gi 446311655 395 LLELEPSN 402
Cdd:COG2956  170 ALKLDPDC 177
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 33-158 1.80e-07

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 50.19  E-value: 1.80e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446311655  33 DALFILGETLYNFGLMPQGLEVFRVLYHKYPDESELLIYFIEGLMSENQTDEALEYLSY---VEP-SPEKLMLEADLYQQ 108
Cdd:COG4783    5 EALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEaleLDPdEPEARLNLGLALLK 84

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|
gi 446311655 109 INMMEVAIAKLQEALELEPNDPIIHFALAEMLYYDGQYLRATSEYETVLE 158
Cdd:COG4783   85 AGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALE 134
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 133-264 2.60e-07

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 49.42  E-value: 2.60e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446311655 133 HFALAEMLYYDGQYLRATSEYETVLETgeyQVNGVNLFSRMADCSLQSGNYSDAIRLYDE-INEDEMTSEDYLKKAISYD 211
Cdd:COG4783    7 LYALAQALLLAGDYDEAEALLEKALEL---DPDNPEAFALLGEILLQLGDLDEAIVLLHEaLELDPDEPEARLNLGLALL 83

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|...
gi 446311655 212 KNDITQEAIKIMTTLLSKDPDYIQGYLYLQSLYENEKNYPDAIETGKEGLRLS 264
Cdd:COG4783   84 KAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELD 136
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 218-325 2.65e-07

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 49.23  E-value: 2.65e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446311655 218 EAIKIMTTLLSKDPDYIQGYLYLQSLYENEKNYPDAIETGKEGLRLSQFYKELMYTTGCLEIEHGDANEGVLLLRQALEV 297
Cdd:COG4235    1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALAL 80

                         90       100
                 ....*....|....*....|....*...
gi 446311655 298 DNAYQEPLLILSDLYRNEEDYEAIIELL 325
Cdd:COG4235   81 DPDNPEALYLLGLAAFQQGDYAEAIAAW 108
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
227-414 2.98e-07

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 51.16  E-value: 2.98e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446311655 227 LSKDPDYIQGYLYLQSLYENEKNYPDAIETGKEGLRLSQFYKELMYTTGCLEIEHGDANEGVLLLRQALEVDNAYQEPLL 306
Cdd:COG0457    1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446311655 307 ILSDLYRNEEDYEAIIELLTYVDEED-LDPTFMWHLAFAYGQEERDKEAQHFFELAYPTMKTNIDFMSDYYFYLTEIGQK 385
Cdd:COG0457   81 NLGLALQALGRYEEALEDYDKALELDpDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRY 160

                        170       180
                 ....*....|....*....|....*....
gi 446311655 386 EQAITILNQLLELEPSNENWHDELSRLQS 414
Cdd:COG0457  161 EEALELLEKLEAAALAALLAAALGEAALA 189
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 272-413 4.36e-07

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 50.88  E-value: 4.36e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446311655 272 YTTGCLEIEHGDANEGVLLLRQALEVDNAYQEPLLILSDLYRNEEDYE-AIIELLTYVDEEDLDPTFMWHLAFAYGQEER 350
Cdd:COG2956   12 YFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDrAIRIHQKLLERDPDRAEALLELAQDYLKAGL 91

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446311655 351 DKEAQHFFELAYPTMKTNIDFMSDYYFYLTEIGQKEQAITILNQLLELEPSNENWHDELSRLQ 413
Cdd:COG2956   92 LDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELY 154
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 76-195 4.42e-07

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 49.03  E-value: 4.42e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446311655  76 LMSENQTDEALEYL-SYVEPSPEK---LMLEADLYQQINMMEVAIAKLQEALELEPNDPIIHFALAEMLYYDGQYLRATS 151
Cdd:COG4783   14 LLLAGDYDEAEALLeKALELDPDNpeaFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEALA 93

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....
gi 446311655 152 EYETVLETGEyqvNGVNLFSRMADCSLQSGNYSDAIRLYDEINE 195
Cdd:COG4783   94 LLEKALKLDP---EHPEAYLRLARAYRALGRPDEAIAALEKALE 134
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 115-264 4.46e-07

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 48.46  E-value: 4.46e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446311655 115 AIAKLQEALELEPNDPIIHFALAEMLYYDGQYLRATSEYETVLetgEYQVNGVNLFSRMADCSLQSGNYSDAIRLYDEIn 194
Cdd:COG4235    2 AIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKAL---RLDPDNADALLDLAEALLAAGDTEEAEELLERA- 77

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446311655 195 edemtsedylkkaisydknditqeaikimttlLSKDPDYIQGYLYLQSLYENEKNYPDAIETGKEGLRLS 264
Cdd:COG4235   78 --------------------------------LALDPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLALL 115
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 26-201 4.56e-07

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 51.92  E-value: 4.56e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446311655  26 AITTDNDDALFILGETLYNFGLMPQGLEVFRVLYHKYPDESELLIYFIEGLMSENQTDEALEYLS-YVEPSPEK----LM 100
Cdd:COG3914  106 ALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRrALELDPDNaealNN 185

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446311655 101 LeADLYQQINMMEVAIAKLQEALELEPNDPIIHFALAEMLYYDGQYlRATSEYETVLETGEYQVNGVNLFSRMADCSLQS 180
Cdd:COG3914  186 L-GNALQDLGRLEEAIAAYRRALELDPDNADAHSNLLFALRQACDW-EVYDRFEELLAALARGPSELSPFALLYLPDDDP 263

                        170       180
                 ....*....|....*....|.
gi 446311655 181 GNYSDAIRLYDEINEDEMTSE 201
Cdd:COG3914  264 AELLALARAWAQLVAAAAAPE 284
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 30-129 8.33e-07

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 48.26  E-value: 8.33e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446311655  30 DNDDALFILGETLYNFGLMPQGLEVFRVLYHKYPDESELLIYFIEGLMSENQTDEALEYLSYV----EPSPEKLMLEADL 105
Cdd:COG4783   36 DNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEALALLEKAlkldPEHPEAYLRLARA 115

                         90       100
                 ....*....|....*....|....
gi 446311655 106 YQQINMMEVAIAKLQEALELEPND 129
Cdd:COG4783  116 YRALGRPDEAIAALEKALELDPDD 139
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 63-159 1.64e-06

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 46.92  E-value: 1.64e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446311655  63 PDESELLIYFIEGLMSENQTDEALEYLSYV----EPSPEKLMLEADLYQQINMMEVAIAKLQEALELEPNDPIIHFALAE 138
Cdd:COG4235   14 PNDAEGWLLLGRAYLRLGRYDEALAAYEKAlrldPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLLGL 93

                         90       100
                 ....*....|....*....|.
gi 446311655 139 MLYYDGQYLRATSEYETVLET 159
Cdd:COG4235   94 AAFQQGDYAEAIAAWQKLLAL 114
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 217-387 1.67e-06

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 50.38  E-value: 1.67e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446311655 217 QEAIKIMTTLLSKDPDYIQGYLYLQSLYENEKNYPDAIETGKEGLRLSQFYKELMYTTGCLEIEHGDANEGVLLLRQALE 296
Cdd:COG3914   95 EEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALE 174

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446311655 297 VDNAYQEPLLILSDLYRNEEDYEAIIELLTYVDEedLDPTFMW---HLAFAYGQEERDKEAQHFFELAYPTMKTNIDFMS 373
Cdd:COG3914  175 LDPDNAEALNNLGNALQDLGRLEEAIAAYRRALE--LDPDNADahsNLLFALRQACDWEVYDRFEELLAALARGPSELSP 252

                        170
                 ....*....|....
gi 446311655 374 DYYFYLTEIGQKEQ 387
Cdd:COG3914  253 FALLYLPDDDPAEL 266
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 101-263 1.81e-06

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 49.99  E-value: 1.81e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446311655 101 LEADLYQQINMMEVAIAKLQEALELEPNDPIIHFALAEMLYYDGQYLRATSEYETVLEtgeYQVNGVNLFSRMADCSLQS 180
Cdd:COG3914   83 LAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALA---LNPDFAEAYLNLGEALRRL 159

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446311655 181 GNYSDAIRLYdeinedemtsedylkkaisydknditQEAIKImttllskDPDYIQGYLYLQSLYENEKNYPDAIETGKEG 260
Cdd:COG3914  160 GRLEEAIAAL--------------------------RRALEL-------DPDNAEALNNLGNALQDLGRLEEAIAAYRRA 206


                 ...
gi 446311655 261 LRL 263
Cdd:COG3914  207 LEL 209
PRK15179 PRK15179
Vi polysaccharide biosynthesis protein TviE; Provisional
 36-158 1.44e-05

Vi polysaccharide biosynthesis protein TviE; Provisional


Pssm-ID: 185101 [Multi-domain]  Cd Length: 694  Bit Score: 47.34  E-value: 1.44e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446311655  36 FILGETLYNFGLMPQGLEVFRVLYHKYPDESELLIYFIEGLMSENQTDEALE----YLSYVEPSPEKLMLEADLYQQINM 111
Cdd:PRK15179  90 VLVARALEAAHRSDEGLAVWRGIHQRFPDSSEAFILMLRGVKRQQGIEAGRAeielYFSGGSSSAREILLEAKSWDEIGQ 169

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*..
gi 446311655 112 MEVAIAKLQEALELEPNDPIIHFALAEMLYYDGQYLRATSEYETVLE 158
Cdd:PRK15179 170 SEQADACFERLSRQHPEFENGYVGWAQSLTRRGALWRARDVLQAGLD 216
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 243-361 1.95e-05

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 44.03  E-value: 1.95e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446311655 243 LYENEKNYPDAIETGKEGLRLSQFYKELMYTTGCLEIEHGDANEGVLLLRQALEVDNAYQEPLLILSDLYRNEEDY-EAI 321
Cdd:COG4783   13 ALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYdEAL 92

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|
gi 446311655 322 IELLTYVDEEDLDPTFMWHLAFAYGQEERDKEAQHFFELA 361
Cdd:COG4783   93 ALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKA 132
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 286-405 2.87e-05

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 43.46  E-value: 2.87e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446311655 286 EGVLLLRQALEVDNAYQEPLLILSDLYRNEEDY-EAIIELLTYVDEEDLDPTFMWHLAFAYGQEERDKEAQHFFELAYPT 364
Cdd:COG4235    1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYdEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALAL 80

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 446311655 365 MKTNIDFMSDYYFYLTEIGQKEQAITILNQLLELEPSNENW 405
Cdd:COG4235   81 DPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLALLPADAPA 121
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 269-402 3.06e-05

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 43.64  E-value: 3.06e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446311655 269 ELMYTTGCLEIEHGDANEGVLLLRQALEVDNAYQEPLLILSDLYRNEEDY-EAIIELLTYVDEEDLDPTFMWHLAFAYGQ 347
Cdd:COG4783    5 EALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLdEAIVLLHEALELDPDEPEARLNLGLALLK 84

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 446311655 348 EERDKEAQHFFELAyptMKTNIDFMSDYYFY---LTEIGQKEQAITILNQLLELEPSN 402
Cdd:COG4783   85 AGDYDEALALLEKA---LKLDPEHPEAYLRLaraYRALGRPDEAIAALEKALELDPDD 139
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 93-402 3.23e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 46.23  E-value: 3.23e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446311655   93 EPSPEKLMLEADLYQQINMMEVAIAKLQEALELEPNDPIIHFALAEMLYYDGQYLRATSEYETVLETGEYQVNGVNLFSR 172
Cdd:TIGR02917  19 DQSPEELIEAAKSYLQKNKYKAAIIQLKNALQKDPNDAEARFLLGKIYLALGDYAAAEKELRKALSLGYPKNQVLPLLAR 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446311655  173 MAdcsLQSGNYSDAIRLYDE--INEDEMTSEDYLKKAISYDKNDITQEAIKIMTTLLSKDPDYIQGYLYLQSLYENEKNY 250
Cdd:TIGR02917  99 AY---LLQGKFQQVLDELPGktLLDDEGAAELLALRGLAYLGLGQLELAQKSYEQALAIDPRSLYAKLGLAQLALAENRF 175

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446311655  251 PDAIETGKEGLRLSQFYKELMYTTGCLEIEHGDANEGVLLLRQALEVDNAYQEPLLILSDLYRNEEDYEaiiELLTYVDE 330
Cdd:TIGR02917 176 DEARALIDEVLTADPGNVDALLLKGDLLLSLGNIELALAAYRKAIALRPNNIAVLLALATILIEAGEFE---EAEKHADA 252

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446311655  331 edLDPTFMWHLAFAYGQ---EERDKEAQHFFELAYPTMKTNIDFM-SDYYFYLTEI--GQKEQAITILNQLLELEPSN 402
Cdd:TIGR02917 253 --LLKKAPNSPLAHYLKalvDFQKKNYEDARETLQDALKSAPEYLpALLLAGASEYqlGNLEQAYQYLNQILKYAPNS 328
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 282-406 5.09e-05

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 45.37  E-value: 5.09e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446311655 282 GDANEGVLLLRQALEVDNAYQEPLLILSDLYRNEEDYEAIIELLTYVDEedLDPTF--MWH-LAFAYGQEERDKEAQHFF 358
Cdd:COG3914   92 GRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALA--LNPDFaeAYLnLGEALRRLGRLEEAIAAL 169

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*...
gi 446311655 359 ELAYPTMKTNIDFMSDYYFYLTEIGQKEQAITILNQLLELEPSNENWH 406
Cdd:COG3914  170 RRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADAH 217
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
105-192 5.50e-05

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 41.69  E-value: 5.50e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446311655 105 LYQQINMMEVAIAKLQEALELEPNDPIIHFALAEMLYYDGQYLRATsEYETVLetgEYQVNGVNLFSRMADCSLQSGNYS 184
Cdd:COG3063    1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAI-ALEKAL---KLDPNNAEALLNLAELLLELGDYD 76


                 ....*...
gi 446311655 185 DAIRLYDE 192
Cdd:COG3063   77 EALAYLER 84
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 172-298 5.65e-05

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 42.87  E-value: 5.65e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446311655 172 RMADCSLQSGNYSDAIRLYDEINEDEMTSED-YLKKAISYDKNDITQEAIKIMTTLLSKDPDYIQGYLYLQSLYENEKNY 250
Cdd:COG4783    9 ALAQALLLAGDYDEAEALLEKALELDPDNPEaFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDY 88

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*...
gi 446311655 251 PDAIETGKEGLRLSQFYKELMYTTGCLEIEHGDANEGVLLLRQALEVD 298
Cdd:COG4783   89 DEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELD 136
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 47-192 1.93e-04

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 41.48  E-value: 1.93e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446311655  47 LMPQGLEVFRVLYHKYPDESELLIYFIEGLMSENQTDEALEYLSYVEPSPEKLMLEADLYQQINMMEVAIAKLQEALELE 126
Cdd:COG5010    5 EGFDRLPLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLD 84

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446311655 127 PNDPIIHFALAEMLYYDGQYLRATSEYETVLETGEyqvNGVNLFSRMADCSLQSGNYSDAIRLYDE 192
Cdd:COG5010   85 PNNPELYYNLALLYSRSGDKDEAKEYYEKALALSP---DNPNAYSNLAALLLSLGQDDEAKAALQR 147
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 115-196 1.25e-03

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 38.43  E-value: 1.25e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446311655 115 AIAKLQEALELEPNDPII---HFALAEMLYYDGQYLRATSEYETVLETGEYQVNGVNLFSRMADCSLQSGNYSDAIRLYD 191
Cdd:COG1729   12 AIAAFKAFLKRYPNSPLApdaLYWLGEAYYALGDYDEAAEAFEKLLKRYPDSPKAPDALLKLGLSYLELGDYDKARATLE 91


                 ....*
gi 446311655 192 EINED 196
Cdd:COG1729   92 ELIKK 96
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
76-158 1.26e-03

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 37.84  E-value: 1.26e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446311655  76 LMSENQTDEALEYLSYV---EPS-PEKLMLEADLYQQINMMEVAIAkLQEALELEPNDPIIHFALAEMLYYDGQYLRATS 151
Cdd:COG3063    2 YLKLGDLEEAEEYYEKAlelDPDnADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELGDYDEALA 80


                 ....*..
gi 446311655 152 EYETVLE 158
Cdd:COG3063   81 YLERALE 87
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 302-412 4.09e-03

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 37.48  E-value: 4.09e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446311655 302 QEPLLILSDLYRNEEDYEAIIELL-TYVDEEDLDPTFMWHLAFAYGQEERDKEAQHFFELAYPTMKTNIDFMSDYYFYLT 380
Cdd:COG4783    4 AEALYALAQALLLAGDYDEAEALLeKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALL 83

                         90       100       110
                 ....*....|....*....|....*....|..
gi 446311655 381 EIGQKEQAITILNQLLELEPSNENWHDELSRL 412
Cdd:COG4783   84 KAGDYDEALALLEKALKLDPEHPEAYLRLARA 115
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 76-158 6.58e-03

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 37.25  E-value: 6.58e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446311655  76 LMSENQTDEALEYLSYV----EPSPEKLMLEADLYQQINMMEVAIAKLQEALELEPNDPIIHFALAEMLYYDGQYLRATS 151
Cdd:COG5010   64 YNKLGDFEESLALLEQAlqldPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKA 143


                 ....*..
gi 446311655 152 EYETVLE 158
Cdd:COG5010  144 ALQRALG 150
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 283-412 6.71e-03

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 37.25  E-value: 6.71e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446311655 283 DANEGVLLLRQALEVDNAYQEPLLILSDLYRNEEDYEAIIELLTYVDEEDLDPTFMWHLAFAYGQEERDKEAQHFFELAY 362
Cdd:COG5010    2 RALEGFDRLPLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQAL 81

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|
gi 446311655 363 PTMKTNIDFMSDYYFYLTEIGQKEQAITILNQLLELEPSNENWHDELSRL 412
Cdd:COG5010   82 QLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAAL 131
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 115-264 9.78e-03

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 36.48  E-value: 9.78e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446311655 115 AIAKLQEALELEPNDPIIHFALAEMLYYDGQYLRATSEYETVLETGEYQVNGVNLFSRMADCSLQSGNYSDAIRLYDE-I 193
Cdd:COG5010    2 RALEGFDRLPLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQaL 81

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446311655 194 NEDEMTSEDYLKKAISYDKNDITQEAIKIMTTLLSKDPDYIQGYLYLQSLYENEKNYPDAIETGKEGLRLS 264
Cdd:COG5010   82 QLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTS 152
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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