|
Name |
Accession |
Description |
Interval |
E-value |
| DnaB |
TIGR00665 |
replicative DNA helicase; This model describes the helicase DnaB, a homohexameric protein ... |
10-459 |
0e+00 |
|
replicative DNA helicase; This model describes the helicase DnaB, a homohexameric protein required for DNA replication. The homohexamer can form a ring around a single strand of DNA near a replication fork. An intein of > 400 residues is found at a conserved location in DnaB of Synechocystis PCC6803, Rhodothermus marinus (both experimentally confirmed), and Mycobacterium tuberculosis. The intein removes itself by a self-splicing reaction. The seed alignment contains inteins so that the model built from the seed alignment will model a low cost at common intein insertion sites. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273206 [Multi-domain] Cd Length: 432 Bit Score: 704.57 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 10 MPHNNEAEQSVLGSIIIDPELINTTQEVLLPESFYRGAHQHIFRAMMHLNEDNKEIDVVTLMDQLSMEGTLNEAGGPQYL 89
Cdd:TIGR00665 1 PPHNIEAEQAVLGAILLDNEAIDDVAEILKPEDFYRPAHRLIFQAILDLYEKGEPIDLVTVAEELEKDGELEEVGGLAYL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 90 AELSTNVPTTRNVQYYTDIVSKHALKRRLIQTADSIANDGYNDELELDAILSDAERRILELSSSRESDGFKDIRDVLGQV 169
Cdd:TIGR00665 81 AELASNVPSAANIEYYAEIVKEKAILRRLIQAGTEIVELAYDPTGDVEELLDEAEQKIFEIAESRTSKGFKSIKEILKEA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 170 YETAEELDQNSGQTPGIPTGYRDLDQMTAGFNRNDLIILAARPSVGKTAFALNIAQKVATHEDMyTVGIFSLEMGADQLA 249
Cdd:TIGR00665 161 VEEIEELYERKGGITGVPTGFTDLDKLTSGLQPSDLIILAARPSMGKTAFALNIAENAAIKEGK-PVAFFSLEMSAEQLV 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 250 TRMICSSGNVDSNRLRTGTMTEEDWSRFTIAVGKLSRTKIFIDDTPGIRINDLRSKCRRLKQEHGLDMIVIDYLQLIQGS 329
Cdd:TIGR00665 240 MRMLSSESRVDSQKLRTGRLSDEDWEKLTEAAGELSEAPLYIDDTPGLTITELRAKARRLKREHGLGLIVIDYLQLMSGS 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 330 GSraSDNRQQEVSEISRTLKALARELECPVIALSQLSRGVEQRQDKRPMMSDIRESGSIEQDADIVAFLYRDDYYNRGgd 409
Cdd:TIGR00665 320 GR--SENRQQEVSEISRSLKALAKELNVPVIALSQLSRSVEQREDKRPQLSDLRESGSIEQDADIVMFLYRDEYYNPD-- 395
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|
gi 446297788 410 edddddggfepqtNDENGEIEIIIAKQRNGPTGTVKLHFMKQYNKFTDID 459
Cdd:TIGR00665 396 -------------SEDKGIAEIIIAKQRNGPTGTVKLAFLGEYTRFENLA 432
|
|
| PRK05748 |
PRK05748 |
replicative DNA helicase; Provisional |
1-464 |
0e+00 |
|
replicative DNA helicase; Provisional
Pssm-ID: 180232 [Multi-domain] Cd Length: 448 Bit Score: 686.30 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 1 MDRMYEQNQMPHNNEAEQSVLGSIIIDPELINTTQEVLLPESFYRGAHQHIFRAMMHLNEDNKEIDVVTLMDQLSMEGTL 80
Cdd:PRK05748 1 MSEVAALRVPPQSIEAEQAVLGAIFLDPDALITVSEYLSPDDFYRHAHRLIFRAMLKLSDRGEPIDVVTVTEILDDQGDL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 81 NEAGGPQYLAELSTNVPTTRNVQYYTDIVSKHALKRRLIQTADSIANDGYNDELELDAILSDAERRILELSSSRESDGFK 160
Cdd:PRK05748 81 EEVGGLSYLAELANSVPTAANIEYYAKIVAEKAMLRRLIRTATEIANDAYEPEDDADEILDEAEKKIFEVSERRNKSGFK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 161 DIRDVLGQVYETAEELDQNSGQTPGIPTGYRDLDQMTAGFNRNDLIILAARPSVGKTAFALNIAQKVATHEDMyTVGIFS 240
Cdd:PRK05748 161 NIKDVLVKAYDRIEMLHNQTGDITGIPTGFTDLDKMTSGLQPNDLIIVAARPSVGKTAFALNIAQNVATKTDK-NVAIFS 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 241 LEMGADQLATRMICSSGNVDSNRLRTGTMTEEDWSRFTIAVGKLSRTKIFIDDTPGIRINDLRSKCRRLKQEH-GLDMIV 319
Cdd:PRK05748 240 LEMGAESLVMRMLCAEGNIDAQRLRTGQLTDDDWPKLTIAMGSLSDAPIYIDDTPGIKVTEIRARCRRLAQEHgGLGLIL 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 320 IDYLQLIQGSGsRASDNRQQEVSEISRTLKALARELECPVIALSQLSRGVEQRQDKRPMMSDIRESGSIEQDADIVAFLY 399
Cdd:PRK05748 320 IDYLQLIQGSG-RSGENRQQEVSEISRSLKALAKELKVPVIALSQLSRGVEQRQDKRPVMSDIRESGSIEQDADIVAFLY 398
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446297788 400 RDDYYNRGGdedddddggfepqtnDENGEIEIIIAKQRNGPTGTVKLHFMKQYNKFTDIDYAHAD 464
Cdd:PRK05748 399 RDDYYDEET---------------ENKNTIEIIIAKQRNGPVGTVELAFQKEYNKFVNLARREED 448
|
|
| DnaB |
COG0305 |
Replicative DNA helicase [Replication, recombination and repair]; |
13-459 |
0e+00 |
|
Replicative DNA helicase [Replication, recombination and repair];
Pssm-ID: 440074 [Multi-domain] Cd Length: 429 Bit Score: 681.80 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 13 NNEAEQSVLGSIIIDPELINTTQEVLLPESFYRGAHQHIFRAMMHLNEDNKEIDVVTLMDQLSMEGTLNEAGGPQYLAEL 92
Cdd:COG0305 1 NIEAEQAVLGALLLDNDALDEVADILKPEDFYRPAHRLIFEAILDLYERGEPIDLVTVAEELEKRGELEEVGGAAYLAEL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 93 STNVPTTRNVQYYTDIVSKHALKRRLIQTADSIANDGYNDELELDAILSDAERRILELSSSRESDGFKDIRDVLGQVYET 172
Cdd:COG0305 81 AENVPSAANIEYYARIVKEKALLRRLIEAGTEIVELAYDEDEDVDELLDEAEQKIFEIAEKRSSKGFVSISDILKEALER 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 173 AEELDQNSGQTPGIPTGYRDLDQMTAGFNRNDLIILAARPSVGKTAFALNIAQKVATHEDMyTVGIFSLEMGADQLATRM 252
Cdd:COG0305 161 IEELYKNGGGITGVPTGFTDLDKLTGGLQPGDLIILAARPSMGKTAFALNIARNAAIKEGK-PVAIFSLEMSAEQLVMRL 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 253 ICSSGNVDSNRLRTGTMTEEDWSRFTIAVGKLSRTKIFIDDTPGIRINDLRSKCRRLKQEHGLDMIVIDYLQLIQGSGSr 332
Cdd:COG0305 240 LSSEARIDSSKLRTGKLSDEDWERLSSAAGELSEAPIYIDDTPGLTIAEIRAKARRLKREHGLGLIVIDYLQLMSGSGR- 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 333 aSDNRQQEVSEISRTLKALARELECPVIALSQLSRGVEQRQDKRPMMSDIRESGSIEQDADIVAFLYRDDYYNRggdedd 412
Cdd:COG0305 319 -SENRQQEISEISRSLKALAKELNVPVIALSQLSRAVEQRTDKRPQLSDLRESGSIEQDADVVMFLYRDEYYNP------ 391
|
410 420 430 440
....*....|....*....|....*....|....*....|....*..
gi 446297788 413 dddggfepqTNDENGEIEIIIAKQRNGPTGTVKLHFMKQYNKFTDID 459
Cdd:COG0305 392 ---------DSEDKGIAEIIIAKQRNGPTGTVKLAFDGEYTRFENLA 429
|
|
| DnaB_C |
pfam03796 |
DnaB-like helicase C terminal domain; The hexameric helicase DnaB unwinds the DNA duplex at ... |
185-457 |
1.19e-171 |
|
DnaB-like helicase C terminal domain; The hexameric helicase DnaB unwinds the DNA duplex at the Escherichia coli chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a change in the quaternary structure of the protein involving dimerization of the N-terminal domain has been observed and may occur during the enzymatic cycle. This C-terminal domain contains an ATP-binding site and is therefore probably the site of ATP hydrolysis.
Pssm-ID: 427509 [Multi-domain] Cd Length: 254 Bit Score: 481.92 E-value: 1.19e-171
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 185 GIPTGYRDLDQMTAGFNRNDLIILAARPSVGKTAFALNIAQKVATHEDMyTVGIFSLEMGADQLATRMICSSGNVDSNRL 264
Cdd:pfam03796 1 GLPTGFTDLDRLTGGLQPGDLIIIAARPSMGKTAFALNIARNAAVKHKK-PVAIFSLEMSAEQLVMRLLASEAGVDSQKL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 265 RTGTMTEEDWSRFTIAVGKLSRTKIFIDDTPGIRINDLRSKCRRLKQEHGLDMIVIDYLQLIQGSgsRASDNRQQEVSEI 344
Cdd:pfam03796 80 RTGQLTDEDWEKLAKAAGRLSEAPLYIDDTPGLSIAEIRAKARRLKREHGLGLIVIDYLQLMSGG--SRGENRQQEISEI 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 345 SRTLKALARELECPVIALSQLSRGVEQRQDKRPMMSDIRESGSIEQDADIVAFLYRDDYYNRGgdedddddggfepqtnD 424
Cdd:pfam03796 158 SRSLKALAKELNVPVIALSQLSRAVEQRTDKRPQLSDLRESGAIEQDADVVMFLYRDEYYNPK----------------E 221
|
250 260 270
....*....|....*....|....*....|...
gi 446297788 425 ENGEIEIIIAKQRNGPTGTVKLHFMKQYNKFTD 457
Cdd:pfam03796 222 PEGKAEIIIAKQRNGPTGTVKLAFLGEYTRFEN 254
|
|
| DnaB_C |
cd00984 |
C-terminal domain of DnaB helicase; DnaB helicase C-terminal domain. The hexameric helicase ... |
185-457 |
1.23e-149 |
|
C-terminal domain of DnaB helicase; DnaB helicase C-terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a change in the quaternary structure of the protein involving dimerization of the N-terminal domain has been observed and may occur during the enzymatic cycle. This C-terminal domain contains an ATP-binding site and is therefore probably the site of ATP hydrolysis.
Pssm-ID: 410864 [Multi-domain] Cd Length: 256 Bit Score: 426.16 E-value: 1.23e-149
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 185 GIPTGYRDLDQMTAGFNRNDLIILAARPSVGKTAFALNIAQKVATHEDMyTVGIFSLEMGADQLATRMICSSGNVDSNRL 264
Cdd:cd00984 1 GLPTGFTDLDKLTGGLQPGDLIIIAARPSMGKTAFALNIAENIALDEGL-PVLFFSLEMSAEQLAERLLSSESGVSLSKL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 265 RTGTMTEEDWSRFTIAVGKLSRTKIFIDDTPGIRINDLRSKCRRLKQEHG-LDMIVIDYLQLIQGSGsrASDNRQQEVSE 343
Cdd:cd00984 80 RTGRLDDEDWERLTAAMGELSELPLYIDDTPGLTVDEIRAKARRLKREHGgLGLIVIDYLQLIRGSK--RAENRQQEVAE 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 344 ISRTLKALARELECPVIALSQLSRGVEQRQDKRPMMSDIRESGSIEQDADIVAFLYRDDYYNRggdedddddggfepqTN 423
Cdd:cd00984 158 ISRSLKALAKELNVPVIALSQLNRGVESRTDKRPMLSDLRESGSIEQDADVVIFLYRDEYYDK---------------DS 222
|
250 260 270
....*....|....*....|....*....|....
gi 446297788 424 DENGEIEIIIAKQRNGPTGTVKLHFMKQYNKFTD 457
Cdd:cd00984 223 EDKGIAEIIIAKNRNGPTGTVYLAFNPEYTRFTD 256
|
|
| dnaB_SPI-7_type |
NF040583 |
SPI-7-type island replicative DNA helicase; Members of this family are DnaB-PI, a ... |
10-458 |
7.11e-144 |
|
SPI-7-type island replicative DNA helicase; Members of this family are DnaB-PI, a pathogenicity island (PI) variant of the replicative DNA helicase DnaB. Members are found with other conjugative element replication proteins such as ParA, ParB in genetic islands whose core proteins (but not cargo proteins) are shared with the Salmonella typhi SPI-7 island.
Pssm-ID: 468557 [Multi-domain] Cd Length: 434 Bit Score: 418.64 E-value: 7.11e-144
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 10 MPHNNEAEQSVLGSIIIDPELINTTQEVLLPESFYRGAHQHIFRAMMHLNEDNKEIDVVTLMDQLSMEGTLNEAGGPQYL 89
Cdd:NF040583 1 GPYSVEAEQSVLGGLMLDNDRWDDVALLLAADDFYSRAHRIIFRAMARLVSAGQPIDLITLSESLEQQGQLEQVGGFAYL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 90 AELSTNVPTTRNVQYYTDIVSKHALKRRLIQTADSIANDGYNDELELDAILSDAERRILELSSSRESDGFKDIRDVLGQV 169
Cdd:NF040583 81 AELSKNTPSAANIVAYAEIVAEYSRARQLLALGHDLSADASAPRADIADLLEQAEQRLFDIAEQAEPQQEVTLIEGLETL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 170 yetAEELDQNSGQTPGI---PTGYRDLDQMTAGFNRNDLIILAARPSVGKTAFALNIAQKVATHEDMYTVGIFSLEMGAD 246
Cdd:NF040583 161 ---VSELELRCQSGNGItgtPTGFAELDEMTCGLQPGDLILLAARPSMGKTALALAFCLGALRGKPDKVVQIYSLEMPTE 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 247 QLATRMICSSGNVDSNRLRTGTMTEEDWSRFTIAVGKLS--RTKIFIDDTPGIRINDLRSKCRRLKQEHGL-DMIVIDYL 323
Cdd:NF040583 238 QLLMRLVSMLGRVPLQRLRSGLLDDEDWARISQAMALLTdwKDRLIIDDTSYLTPALLRARARRNARKYGKpSLIMVDYL 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 324 QLIQGSGSrasDNRQQEVSEISRTLKALARELECPVIALSQLSRGVEQRQDKRPMMSDIRESGSIEQDADIVAFLYRDDY 403
Cdd:NF040583 318 QLMRCPGQ---ENRTQEIAEISRSLKALAKEMGCPVLALSQLNRQLESRADKRPNNGDLRDSGALEQDADLIMFIYRDEV 394
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*
gi 446297788 404 YNrggdedddddggfePQTNDEnGEIEIIIAKQRNGPTGTVKLHFMKQYNKFTDI 458
Cdd:NF040583 395 YN--------------PNTPDK-GIAEIIIGKQRQGPTGTVKVQFDGRYTRFSDL 434
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| DnaB |
TIGR00665 |
replicative DNA helicase; This model describes the helicase DnaB, a homohexameric protein ... |
10-459 |
0e+00 |
|
replicative DNA helicase; This model describes the helicase DnaB, a homohexameric protein required for DNA replication. The homohexamer can form a ring around a single strand of DNA near a replication fork. An intein of > 400 residues is found at a conserved location in DnaB of Synechocystis PCC6803, Rhodothermus marinus (both experimentally confirmed), and Mycobacterium tuberculosis. The intein removes itself by a self-splicing reaction. The seed alignment contains inteins so that the model built from the seed alignment will model a low cost at common intein insertion sites. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273206 [Multi-domain] Cd Length: 432 Bit Score: 704.57 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 10 MPHNNEAEQSVLGSIIIDPELINTTQEVLLPESFYRGAHQHIFRAMMHLNEDNKEIDVVTLMDQLSMEGTLNEAGGPQYL 89
Cdd:TIGR00665 1 PPHNIEAEQAVLGAILLDNEAIDDVAEILKPEDFYRPAHRLIFQAILDLYEKGEPIDLVTVAEELEKDGELEEVGGLAYL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 90 AELSTNVPTTRNVQYYTDIVSKHALKRRLIQTADSIANDGYNDELELDAILSDAERRILELSSSRESDGFKDIRDVLGQV 169
Cdd:TIGR00665 81 AELASNVPSAANIEYYAEIVKEKAILRRLIQAGTEIVELAYDPTGDVEELLDEAEQKIFEIAESRTSKGFKSIKEILKEA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 170 YETAEELDQNSGQTPGIPTGYRDLDQMTAGFNRNDLIILAARPSVGKTAFALNIAQKVATHEDMyTVGIFSLEMGADQLA 249
Cdd:TIGR00665 161 VEEIEELYERKGGITGVPTGFTDLDKLTSGLQPSDLIILAARPSMGKTAFALNIAENAAIKEGK-PVAFFSLEMSAEQLV 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 250 TRMICSSGNVDSNRLRTGTMTEEDWSRFTIAVGKLSRTKIFIDDTPGIRINDLRSKCRRLKQEHGLDMIVIDYLQLIQGS 329
Cdd:TIGR00665 240 MRMLSSESRVDSQKLRTGRLSDEDWEKLTEAAGELSEAPLYIDDTPGLTITELRAKARRLKREHGLGLIVIDYLQLMSGS 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 330 GSraSDNRQQEVSEISRTLKALARELECPVIALSQLSRGVEQRQDKRPMMSDIRESGSIEQDADIVAFLYRDDYYNRGgd 409
Cdd:TIGR00665 320 GR--SENRQQEVSEISRSLKALAKELNVPVIALSQLSRSVEQREDKRPQLSDLRESGSIEQDADIVMFLYRDEYYNPD-- 395
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|
gi 446297788 410 edddddggfepqtNDENGEIEIIIAKQRNGPTGTVKLHFMKQYNKFTDID 459
Cdd:TIGR00665 396 -------------SEDKGIAEIIIAKQRNGPTGTVKLAFLGEYTRFENLA 432
|
|
| PRK05748 |
PRK05748 |
replicative DNA helicase; Provisional |
1-464 |
0e+00 |
|
replicative DNA helicase; Provisional
Pssm-ID: 180232 [Multi-domain] Cd Length: 448 Bit Score: 686.30 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 1 MDRMYEQNQMPHNNEAEQSVLGSIIIDPELINTTQEVLLPESFYRGAHQHIFRAMMHLNEDNKEIDVVTLMDQLSMEGTL 80
Cdd:PRK05748 1 MSEVAALRVPPQSIEAEQAVLGAIFLDPDALITVSEYLSPDDFYRHAHRLIFRAMLKLSDRGEPIDVVTVTEILDDQGDL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 81 NEAGGPQYLAELSTNVPTTRNVQYYTDIVSKHALKRRLIQTADSIANDGYNDELELDAILSDAERRILELSSSRESDGFK 160
Cdd:PRK05748 81 EEVGGLSYLAELANSVPTAANIEYYAKIVAEKAMLRRLIRTATEIANDAYEPEDDADEILDEAEKKIFEVSERRNKSGFK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 161 DIRDVLGQVYETAEELDQNSGQTPGIPTGYRDLDQMTAGFNRNDLIILAARPSVGKTAFALNIAQKVATHEDMyTVGIFS 240
Cdd:PRK05748 161 NIKDVLVKAYDRIEMLHNQTGDITGIPTGFTDLDKMTSGLQPNDLIIVAARPSVGKTAFALNIAQNVATKTDK-NVAIFS 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 241 LEMGADQLATRMICSSGNVDSNRLRTGTMTEEDWSRFTIAVGKLSRTKIFIDDTPGIRINDLRSKCRRLKQEH-GLDMIV 319
Cdd:PRK05748 240 LEMGAESLVMRMLCAEGNIDAQRLRTGQLTDDDWPKLTIAMGSLSDAPIYIDDTPGIKVTEIRARCRRLAQEHgGLGLIL 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 320 IDYLQLIQGSGsRASDNRQQEVSEISRTLKALARELECPVIALSQLSRGVEQRQDKRPMMSDIRESGSIEQDADIVAFLY 399
Cdd:PRK05748 320 IDYLQLIQGSG-RSGENRQQEVSEISRSLKALAKELKVPVIALSQLSRGVEQRQDKRPVMSDIRESGSIEQDADIVAFLY 398
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446297788 400 RDDYYNRGGdedddddggfepqtnDENGEIEIIIAKQRNGPTGTVKLHFMKQYNKFTDIDYAHAD 464
Cdd:PRK05748 399 RDDYYDEET---------------ENKNTIEIIIAKQRNGPVGTVELAFQKEYNKFVNLARREED 448
|
|
| DnaB |
COG0305 |
Replicative DNA helicase [Replication, recombination and repair]; |
13-459 |
0e+00 |
|
Replicative DNA helicase [Replication, recombination and repair];
Pssm-ID: 440074 [Multi-domain] Cd Length: 429 Bit Score: 681.80 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 13 NNEAEQSVLGSIIIDPELINTTQEVLLPESFYRGAHQHIFRAMMHLNEDNKEIDVVTLMDQLSMEGTLNEAGGPQYLAEL 92
Cdd:COG0305 1 NIEAEQAVLGALLLDNDALDEVADILKPEDFYRPAHRLIFEAILDLYERGEPIDLVTVAEELEKRGELEEVGGAAYLAEL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 93 STNVPTTRNVQYYTDIVSKHALKRRLIQTADSIANDGYNDELELDAILSDAERRILELSSSRESDGFKDIRDVLGQVYET 172
Cdd:COG0305 81 AENVPSAANIEYYARIVKEKALLRRLIEAGTEIVELAYDEDEDVDELLDEAEQKIFEIAEKRSSKGFVSISDILKEALER 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 173 AEELDQNSGQTPGIPTGYRDLDQMTAGFNRNDLIILAARPSVGKTAFALNIAQKVATHEDMyTVGIFSLEMGADQLATRM 252
Cdd:COG0305 161 IEELYKNGGGITGVPTGFTDLDKLTGGLQPGDLIILAARPSMGKTAFALNIARNAAIKEGK-PVAIFSLEMSAEQLVMRL 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 253 ICSSGNVDSNRLRTGTMTEEDWSRFTIAVGKLSRTKIFIDDTPGIRINDLRSKCRRLKQEHGLDMIVIDYLQLIQGSGSr 332
Cdd:COG0305 240 LSSEARIDSSKLRTGKLSDEDWERLSSAAGELSEAPIYIDDTPGLTIAEIRAKARRLKREHGLGLIVIDYLQLMSGSGR- 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 333 aSDNRQQEVSEISRTLKALARELECPVIALSQLSRGVEQRQDKRPMMSDIRESGSIEQDADIVAFLYRDDYYNRggdedd 412
Cdd:COG0305 319 -SENRQQEISEISRSLKALAKELNVPVIALSQLSRAVEQRTDKRPQLSDLRESGSIEQDADVVMFLYRDEYYNP------ 391
|
410 420 430 440
....*....|....*....|....*....|....*....|....*..
gi 446297788 413 dddggfepqTNDENGEIEIIIAKQRNGPTGTVKLHFMKQYNKFTDID 459
Cdd:COG0305 392 ---------DSEDKGIAEIIIAKQRNGPTGTVKLAFDGEYTRFENLA 429
|
|
| PRK05595 |
PRK05595 |
replicative DNA helicase; Provisional |
10-464 |
0e+00 |
|
replicative DNA helicase; Provisional
Pssm-ID: 235525 [Multi-domain] Cd Length: 444 Bit Score: 513.22 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 10 MPHNNEAEQSVLGSIIIDPELINTTQEVLLPESFYRGAHQHIFRAMMHLNEDNKEIDVVTLMDQLSMEGTLNEAGGPQYL 89
Cdd:PRK05595 8 LPQSIEAEQSVLGAMIIDKTSIAEAAEVLKSEDFYRDSHKVIFSAIIELYQKDIAVDMLTLTENLKSTDKLEAAGGVTYI 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 90 AELSTNVPTTRNVQYYTDIVSKHALKRRLIQTADSIANDGYNDELELDAILSDAERRILELSSSRESDGFKDIRDVLGQV 169
Cdd:PRK05595 88 TELSNSIVSTANIQSYIKIVKDKSTLRRLIKSSTEIIENSYNNQDDVEKVIDSAEKKIFDISEKRTTSDFEPLSNVLERG 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 170 YETAEELDQNSGQTPGIPTGYRDLDQMTAGFNRNDLIILAARPSVGKTAFALNIAQKVATHEDMyTVGIFSLEMGADQLA 249
Cdd:PRK05595 168 FEQIENLFNNKGETTGVASGFRELDAKTSGFQKGDMILIAARPSMGKTTFALNIAEYAALREGK-SVAIFSLEMSKEQLA 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 250 TRMICSSGNVDSNRLRTGTMTEEDWSRFTIAVGKLSRTKIFIDDTPGIRINDLRSKCRRLKQEHGLDMIVIDYLQLIqgS 329
Cdd:PRK05595 247 YKLLCSEANVDMLRLRTGNLEDKDWENIARASGPLAAAKIFIDDTAGVSVMEMRSKCRRLKIEHGIDMILIDYLQLM--S 324
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 330 GSRASDNRQQEVSEISRTLKALARELECPVIALSQLSRGVEQRQDKRPMMSDIRESGSIEQDADIVAFLYRDDYYNRggd 409
Cdd:PRK05595 325 GGKGSESRQQEVSEISRSIKALAKEMECPVIALSQLSRAPEQRADHRPMLSDLRESGSIEQDADVVMFLYRDEYYNK--- 401
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*
gi 446297788 410 edddddggfepQTNDENgEIEIIIAKQRNGPTGTVKLHFMKQYNKFTDIDYAHAD 464
Cdd:PRK05595 402 -----------ETEDKN-VAECIIAKQRNGPTGTVKLAWLGQYSKFGNLDVIHQE 444
|
|
| PRK09165 |
PRK09165 |
replicative DNA helicase; Provisional |
6-459 |
3.77e-172 |
|
replicative DNA helicase; Provisional
Pssm-ID: 181676 [Multi-domain] Cd Length: 497 Bit Score: 492.86 E-value: 3.77e-172
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 6 EQNQMPHNNEAEQSVLGSIIIDPELINTTQEVLLPESFYRGAHQHIFRAMMHLNEDNKEIDVVTLMDQLSMEGTLNEAGG 85
Cdd:PRK09165 17 EIRELPHNIEAEQALLGAILINNRALDRVSDFLKPEHFFEPLHQRIYEAIAKIIRKGKLATPVTLKTFLENDEALGELGG 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 86 PQYLAELSTNVPTTRNVQYYTDIVSKHALKRRLIQTADSIANDGYNDELELDAI--LSDAERRILELSSSRESD-GFKDI 162
Cdd:PRK09165 97 VQYLAKLATEAVTIINARDYGRIIYDLALRRELINIGEDVVNNAYDAPVDVAPQeqIEDAEQKLYELAETGRYEgGFQSF 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 163 RDVLGQVYETAEELDQNSGQTPGIPTGYRDLDQMTAGFNRNDLIILAARPSVGKTAFALNIAQKVA-------------T 229
Cdd:PRK09165 177 GTAITEAVDMANAAFKRDGHLSGISTGLRDLDSKLGGLHPSDLIILAGRPSMGKTALATNIAFNAAkayrreaqpdgskK 256
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 230 HEDMYTVGIFSLEMGADQLATRMICSSGNVDSNRLRTGTMTEEDWSRFTIAVGKLSRTKIFIDDTPGIRINDLRSKCRRL 309
Cdd:PRK09165 257 AVNGGVVGFFSLEMSAEQLATRILSEQSEISSSKIRRGKISEEDFEKLVDASQELQKLPLYIDDTPALSISQLRARARRL 336
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 310 KQEHGLDMIVIDYLQLIQGSGSRASDNRQQEVSEISRTLKALARELECPVIALSQLSRGVEQRQDKRPMMSDIRESGSIE 389
Cdd:PRK09165 337 KRQHGLDLLVVDYLQLIRGSSKRSSDNRVQEISEITQGLKALAKELNIPVIALSQLSRQVEQRDDKRPQLSDLRESGSIE 416
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446297788 390 QDADIVAFLYRDDYY--NRGGDEDDDDDGGFEPQTNDENGEIEIIIAKQRNGPTGTVKLHFMKQYNKFTDID 459
Cdd:PRK09165 417 QDADVVMFVYREEYYlkRKEPREGTPKHEEWQEKMEKVHNKAEVIIAKQRHGPTGTVKLAFESEFTRFGDLA 488
|
|
| DnaB_C |
pfam03796 |
DnaB-like helicase C terminal domain; The hexameric helicase DnaB unwinds the DNA duplex at ... |
185-457 |
1.19e-171 |
|
DnaB-like helicase C terminal domain; The hexameric helicase DnaB unwinds the DNA duplex at the Escherichia coli chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a change in the quaternary structure of the protein involving dimerization of the N-terminal domain has been observed and may occur during the enzymatic cycle. This C-terminal domain contains an ATP-binding site and is therefore probably the site of ATP hydrolysis.
Pssm-ID: 427509 [Multi-domain] Cd Length: 254 Bit Score: 481.92 E-value: 1.19e-171
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 185 GIPTGYRDLDQMTAGFNRNDLIILAARPSVGKTAFALNIAQKVATHEDMyTVGIFSLEMGADQLATRMICSSGNVDSNRL 264
Cdd:pfam03796 1 GLPTGFTDLDRLTGGLQPGDLIIIAARPSMGKTAFALNIARNAAVKHKK-PVAIFSLEMSAEQLVMRLLASEAGVDSQKL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 265 RTGTMTEEDWSRFTIAVGKLSRTKIFIDDTPGIRINDLRSKCRRLKQEHGLDMIVIDYLQLIQGSgsRASDNRQQEVSEI 344
Cdd:pfam03796 80 RTGQLTDEDWEKLAKAAGRLSEAPLYIDDTPGLSIAEIRAKARRLKREHGLGLIVIDYLQLMSGG--SRGENRQQEISEI 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 345 SRTLKALARELECPVIALSQLSRGVEQRQDKRPMMSDIRESGSIEQDADIVAFLYRDDYYNRGgdedddddggfepqtnD 424
Cdd:pfam03796 158 SRSLKALAKELNVPVIALSQLSRAVEQRTDKRPQLSDLRESGAIEQDADVVMFLYRDEYYNPK----------------E 221
|
250 260 270
....*....|....*....|....*....|...
gi 446297788 425 ENGEIEIIIAKQRNGPTGTVKLHFMKQYNKFTD 457
Cdd:pfam03796 222 PEGKAEIIIAKQRNGPTGTVKLAFLGEYTRFEN 254
|
|
| PRK07773 |
PRK07773 |
replicative DNA helicase; Validated |
11-394 |
7.14e-151 |
|
replicative DNA helicase; Validated
Pssm-ID: 236093 [Multi-domain] Cd Length: 886 Bit Score: 451.51 E-value: 7.14e-151
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 11 PHNNEAEQSVLGSIIIDPELINTTQEVLLPESFYRGAHQHIFRAMMHLNEDNKEIDVVTLMDQLSMEGTLNEAGGPQYLA 90
Cdd:PRK07773 25 PQDLAAEQSVLGGMLLSKEAIARVLERLRPGAFYRPAHQNIYDAILDLYGRGEPADLVTVAAELDRRGLLERIGGAPYLH 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 91 ELSTNVPTTRNVQYYTDIVSKHALKRRLIQTADSIANDGYNDELELDAILSDAERRILELSSSRESDGFKDIRDVLGQVY 170
Cdd:PRK07773 105 TLISTVPTAANADYYARIVAEKALLRRLIEAGTRIVQYGYAEGADVAEVVDRAQAEIYDVTDRRLSEDFVALEDLLQPTF 184
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 171 ETAEELDQNSGQTPGIPTGYRDLDQMTAGFNRNDLIILAARPSVGKTAFALNIAQKVATHEDMyTVGIFSLEMGADQLAT 250
Cdd:PRK07773 185 DEIDAIASSGGLARGVPTGFTELDAMTNGLHPGQLIIVAARPSMGKTTFGLDFARNCAIRHRL-AVAIFSLEMSKEQLVM 263
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 251 RMICSSGNVDSNRLRTGTMTEEDWSRFTIAVGKLSRTKIFIDDTPGIRINDLRSKCRRLKQEHGLDMIVIDYLQLIQgsG 330
Cdd:PRK07773 264 RLLSAEAKIKLSDMRSGRMSDDDWTRLARAMGEISEAPIFIDDTPNLTVMEIRAKARRLRQEANLGLIVVDYLQLMT--S 341
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446297788 331 SRASDNRQQEVSEISRTLKALARELECPVIALSQLSRGVEQRQDKRPMMSDIRESGSIEQDADI 394
Cdd:PRK07773 342 GKKYENRQQEVSEISRHLKLLAKELEVPVVALSQLSRGVEQRTDKRPMLSDLRESGCLTGDTLI 405
|
|
| PRK08760 |
PRK08760 |
replicative DNA helicase; Provisional |
11-458 |
5.84e-150 |
|
replicative DNA helicase; Provisional
Pssm-ID: 181547 [Multi-domain] Cd Length: 476 Bit Score: 435.50 E-value: 5.84e-150
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 11 PHNNEAEQSVLGSIIIDPELINTTQEVLLPESFYRGAHQHIFRAMMHLNEDNKEIDVVTLMDQLSMEGTLNEAGGPQYLA 90
Cdd:PRK08760 34 PHSVEAEQAVLGGLMLAPDALDRVNDQLTENDFYRRDHRLIYRAIRELSEKDRPFDAVTLGEWFESQGKLEQVGDGAYLI 113
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 91 ELSTNVPTTRNVQYYTDIVSKHALKRRLIQTADSIANDGYNDE-LELDAILSDAERRILELSSS--RESDGFKDIRDVLG 167
Cdd:PRK08760 114 ELASTTPSAANIAAYAEIVRDKAVLRQLIEVGTTIVNDGFQPEgRESIELLASAEKAVFKIAEAgaRGRTDFVAMPGALK 193
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 168 QVYETAEELDQNSGQTPGIPTGYRDLDQMTAGFNRNDLIILAARPSVGKTAFALNIAQKVATHEDMyTVGIFSLEMGADQ 247
Cdd:PRK08760 194 DAFEELRNRFENGGNITGLPTGYNDFDAMTAGLQPTDLIILAARPAMGKTTFALNIAEYAAIKSKK-GVAVFSMEMSASQ 272
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 248 LATRMICSSGNVDSNRLRTGTMTEEDWSRFTIAVGKLSRTKIFIDDTPGIRINDLRSKCRRLKQEHGLDMIVIDYLQLIQ 327
Cdd:PRK08760 273 LAMRLISSNGRINAQRLRTGALEDEDWARVTGAIKMLKETKIFIDDTPGVSPEVLRSKCRRLKREHDLGLIVIDYLQLMS 352
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 328 GSGSraSDNRQQEVSEISRTLKALARELECPVIALSQLSRGVEQRQDKRPMMSDIRESGSIEQDADIVAFLYRDDYYNRg 407
Cdd:PRK08760 353 VPGN--SENRATEISEISRSLKGLAKELNVPVIALSQLNRSLETRTDKRPVMADLRESGAIEQDADMIVFIYRDDYYNK- 429
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|.
gi 446297788 408 gdedddddggfepQTNDENGEIEIIIAKQRNGPTGTVKLHFMKQYNKFTDI 458
Cdd:PRK08760 430 -------------ENSPDKGLAEIIIGKHRGGPTGSCKLKFFGEYTRFDNL 467
|
|
| DnaB_C |
cd00984 |
C-terminal domain of DnaB helicase; DnaB helicase C-terminal domain. The hexameric helicase ... |
185-457 |
1.23e-149 |
|
C-terminal domain of DnaB helicase; DnaB helicase C-terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a change in the quaternary structure of the protein involving dimerization of the N-terminal domain has been observed and may occur during the enzymatic cycle. This C-terminal domain contains an ATP-binding site and is therefore probably the site of ATP hydrolysis.
Pssm-ID: 410864 [Multi-domain] Cd Length: 256 Bit Score: 426.16 E-value: 1.23e-149
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 185 GIPTGYRDLDQMTAGFNRNDLIILAARPSVGKTAFALNIAQKVATHEDMyTVGIFSLEMGADQLATRMICSSGNVDSNRL 264
Cdd:cd00984 1 GLPTGFTDLDKLTGGLQPGDLIIIAARPSMGKTAFALNIAENIALDEGL-PVLFFSLEMSAEQLAERLLSSESGVSLSKL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 265 RTGTMTEEDWSRFTIAVGKLSRTKIFIDDTPGIRINDLRSKCRRLKQEHG-LDMIVIDYLQLIQGSGsrASDNRQQEVSE 343
Cdd:cd00984 80 RTGRLDDEDWERLTAAMGELSELPLYIDDTPGLTVDEIRAKARRLKREHGgLGLIVIDYLQLIRGSK--RAENRQQEVAE 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 344 ISRTLKALARELECPVIALSQLSRGVEQRQDKRPMMSDIRESGSIEQDADIVAFLYRDDYYNRggdedddddggfepqTN 423
Cdd:cd00984 158 ISRSLKALAKELNVPVIALSQLNRGVESRTDKRPMLSDLRESGSIEQDADVVIFLYRDEYYDK---------------DS 222
|
250 260 270
....*....|....*....|....*....|....
gi 446297788 424 DENGEIEIIIAKQRNGPTGTVKLHFMKQYNKFTD 457
Cdd:cd00984 223 EDKGIAEIIIAKNRNGPTGTVYLAFNPEYTRFTD 256
|
|
| dnaB_SPI-7_type |
NF040583 |
SPI-7-type island replicative DNA helicase; Members of this family are DnaB-PI, a ... |
10-458 |
7.11e-144 |
|
SPI-7-type island replicative DNA helicase; Members of this family are DnaB-PI, a pathogenicity island (PI) variant of the replicative DNA helicase DnaB. Members are found with other conjugative element replication proteins such as ParA, ParB in genetic islands whose core proteins (but not cargo proteins) are shared with the Salmonella typhi SPI-7 island.
Pssm-ID: 468557 [Multi-domain] Cd Length: 434 Bit Score: 418.64 E-value: 7.11e-144
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 10 MPHNNEAEQSVLGSIIIDPELINTTQEVLLPESFYRGAHQHIFRAMMHLNEDNKEIDVVTLMDQLSMEGTLNEAGGPQYL 89
Cdd:NF040583 1 GPYSVEAEQSVLGGLMLDNDRWDDVALLLAADDFYSRAHRIIFRAMARLVSAGQPIDLITLSESLEQQGQLEQVGGFAYL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 90 AELSTNVPTTRNVQYYTDIVSKHALKRRLIQTADSIANDGYNDELELDAILSDAERRILELSSSRESDGFKDIRDVLGQV 169
Cdd:NF040583 81 AELSKNTPSAANIVAYAEIVAEYSRARQLLALGHDLSADASAPRADIADLLEQAEQRLFDIAEQAEPQQEVTLIEGLETL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 170 yetAEELDQNSGQTPGI---PTGYRDLDQMTAGFNRNDLIILAARPSVGKTAFALNIAQKVATHEDMYTVGIFSLEMGAD 246
Cdd:NF040583 161 ---VSELELRCQSGNGItgtPTGFAELDEMTCGLQPGDLILLAARPSMGKTALALAFCLGALRGKPDKVVQIYSLEMPTE 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 247 QLATRMICSSGNVDSNRLRTGTMTEEDWSRFTIAVGKLS--RTKIFIDDTPGIRINDLRSKCRRLKQEHGL-DMIVIDYL 323
Cdd:NF040583 238 QLLMRLVSMLGRVPLQRLRSGLLDDEDWARISQAMALLTdwKDRLIIDDTSYLTPALLRARARRNARKYGKpSLIMVDYL 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 324 QLIQGSGSrasDNRQQEVSEISRTLKALARELECPVIALSQLSRGVEQRQDKRPMMSDIRESGSIEQDADIVAFLYRDDY 403
Cdd:NF040583 318 QLMRCPGQ---ENRTQEIAEISRSLKALAKEMGCPVLALSQLNRQLESRADKRPNNGDLRDSGALEQDADLIMFIYRDEV 394
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*
gi 446297788 404 YNrggdedddddggfePQTNDEnGEIEIIIAKQRNGPTGTVKLHFMKQYNKFTDI 458
Cdd:NF040583 395 YN--------------PNTPDK-GIAEIIIGKQRQGPTGTVKVQFDGRYTRFSDL 434
|
|
| PRK07004 |
PRK07004 |
replicative DNA helicase; Provisional |
11-455 |
9.16e-144 |
|
replicative DNA helicase; Provisional
Pssm-ID: 235907 [Multi-domain] Cd Length: 460 Bit Score: 419.32 E-value: 9.16e-144
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 11 PHNNEAEQSVLGSIIIDPELINTTQEVLLPESFYRGAHQHIFRAMMHLNEDNKEIDVVTLMDQLSMEGTLNEAGGPQYLA 90
Cdd:PRK07004 16 PHSIEAEQSVLGGLLLDNAAWDRIADFLSQSDFYRYDHRIIFEHIGRLIAATRPADVITVYEALTTSGKAEEVGGLAYLN 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 91 ELSTNVPTTRNVQYYTDIVSKHALKRRLIQTADSIANDGYNDE-LELDAILSDAERRILELSS--SRESDGFKDIRDVLG 167
Cdd:PRK07004 96 ALAQNTPSAANIRRYAEIVRDRAVLRRLVSVADEISADAFNPQgKEVRQLLDEAESKVFSIAEegARGTQGFLEIGPLLT 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 168 QVYETAEELDQNSGQT--PGIPTGYRDLDQMTAGFNRNDLIILAARPSVGKTAFALNIAQKVATHEDMyTVGIFSLEMGA 245
Cdd:PRK07004 176 QVVERIDTLYHTANPSdvTGTPTGFVDLDRMTSGMHGGELIIVAGRPSMGKTAFSMNIGEYVAVEYGL-PVAVFSMEMPG 254
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 246 DQLATRMICSSGNVDSNRLRTGTMTEEDWSRFTIAVGKLSRTKIFIDDTPGIRINDLRSKCRRLKQEHG-LDMIVIDYLQ 324
Cdd:PRK07004 255 TQLAMRMLGSVGRLDQHRMRTGRLTDEDWPKLTHAVQKMSEAQLFIDETGGLNPMELRSRARRLARQCGkLGLIIIDYLQ 334
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 325 LIQGSGSraSDNRQQEVSEISRTLKALARELECPVIALSQLSRGVEQRQDKRPMMSDIRESGSIEQDADIVAFLYRDDYY 404
Cdd:PRK07004 335 LMSGSSQ--GENRATEISEISRSLKSLAKELDVPVIALSQLNRGLEQRPNKRPVMSDLRESGAIEQDADVILFIYRDEVY 412
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|.
gi 446297788 405 NrggdedddddggfePQTNDEnGEIEIIIAKQRNGPTGTVKLHFMKQYNKF 455
Cdd:PRK07004 413 N--------------PDSPDK-GTAEIIIGKQRNGPIGPVRLTFLGQYTKF 448
|
|
| phage_DnaB |
TIGR03600 |
phage replicative helicase, DnaB family, HK022 subfamily; Members of this family are phage (or ... |
15-448 |
8.34e-140 |
|
phage replicative helicase, DnaB family, HK022 subfamily; Members of this family are phage (or prophage-region) homologs of the bacterial homohexameric replicative helicase DnaB. Some phage may rely on host DnaB, while others encode their own verions. This model describes the largest phage-specific clade among the close homologs of DnaB, but there are, or course, other DnaB homologs from phage that fall outside the scope of this model. [Mobile and extrachromosomal element functions, Prophage functions]
Pssm-ID: 274672 [Multi-domain] Cd Length: 420 Bit Score: 407.56 E-value: 8.34e-140
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 15 EAEQSVLGSIIIDPELINTTQEVLLPESFYRGAHQHIFRAMMHLNEDNKEIDVVTLMDQLSMEGTLNEAGGPQYLAELST 94
Cdd:TIGR03600 3 EAEQAVLGGLLLDNDFIERVMAILKPEHFYSQDHRIIFEAMLDMFAENRPVDPLTLADKLEAEGEAEKVGGLAYLAEISN 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 95 NVPTTRNVQYYTDIVSKHALKRRLIQTADSIANDGYNDE-LELDAILSDAERRILELSSSRES-DGFKDIRDVLGQVYET 172
Cdd:TIGR03600 83 NTPSAANISSYARIVREKAKERKLIAACQRIITLACSPDgGTAEQKVEEAQAALLALTMSDGQeDGFVTFGEVLEDVVRD 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 173 AEELDQNSGQTPGIPTGYRDLDQMTAGFNRNDLIILAARPSVGKTAFALNIAQKVATHEDMyTVGIFSLEMGADQLATRM 252
Cdd:TIGR03600 163 LDKRFNPKGELTGLSTGLPKLDRLTNGLVKGDLIVIGARPSMGKTTLALNIAENVALREGK-PVLFFSLEMSAEQLGERL 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 253 ICSSGNVDSNRLRTGTMTEEDWSRFTIAVGKLSRTKIFIDDTPGIRINDLRSKCRRLKQEH-GLDMIVIDYLQLIQGSGS 331
Cdd:TIGR03600 242 LASKSGINTGNIRTGRFNDSEFNRLLNAVDRLSEKDLYIDDTGGLTVAQIRSIARRIKRKKgGLDLIVVDYIQLMAPARG 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 332 RasdNRQQEVSEISRTLKALARELECPVIALSQLSRGVEQRQDKRPMMSDIRESGSIEQDADIVAFLYRDDYYNrggded 411
Cdd:TIGR03600 322 R---DRNEELGGISRGLKALAKELDVPVVLLAQLNRGSEKRTDKRPIMSDLRDSGAIEQDADVIGLIHREGYYD------ 392
|
410 420 430
....*....|....*....|....*....|....*..
gi 446297788 412 ddddggfepQTNDENGEIEIIIAKQRNGPTGTVKLHF 448
Cdd:TIGR03600 393 ---------AREPPAGIAELILAKNRHGPTGTVELLF 420
|
|
| PRK05636 |
PRK05636 |
replicative DNA helicase; Provisional |
6-463 |
9.22e-136 |
|
replicative DNA helicase; Provisional
Pssm-ID: 180177 [Multi-domain] Cd Length: 505 Bit Score: 400.37 E-value: 9.22e-136
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 6 EQNQMPHNNEAEQSVLGSIIIDPELINTTQEVLLPESFYRGAHQHIFRAMMHLNEDNKEIDVVTLMDQLSMEGTLNEAGG 85
Cdd:PRK05636 66 DFRQPPYDNEAEQGVLGAMLLSPDTVIDIVEVLTPEDFYRPAHQLIFQAIIDLFSDNKEIDPVIVAGRLDRTNDLERVGG 145
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 86 PQYLAELSTNVPTTRNVQYYTDIVSKHALKRRLIQTADSIANDGY--NDELELDAILSDAERRILELSSSRESDGFKDIR 163
Cdd:PRK05636 146 APYLHTLIQSVPTAANARYYAEIVSEKAVLRRLVDAGTRVVQLGYegDEGAEIDSVIDRAQQEVFAVSQKNQSEDYAVLA 225
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 164 DVLGQVYETAEELDQNSGQTPGIPTGYRDLDQMTAGFNRNDLIILAARPSVGKTAFALNIAQKVATHEDMYTVgIFSLEM 243
Cdd:PRK05636 226 DILDPTMDELEMLSSQGGIATGIPTGFKDLDDLTNGLRGGQMIIVAARPGVGKSTLALDFMRSASIKHNKASV-IFSLEM 304
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 244 GADQLATRMICSSGNVDSNRLRTGTMTEEDWSRFTIAVGKLSRTKIFIDDTPGIRINDLRSKCRRLKQEHGLDMIVIDYL 323
Cdd:PRK05636 305 SKSEIVMRLLSAEAEVRLSDMRGGKMDEDAWEKLVQRLGKIAQAPIFIDDSANLTMMEIRSKARRLKQKHDLKLIVVDYL 384
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 324 QLIQgSGSRAsDNRQQEVSEISRTLKALARELECPVIALSQLSRGVEQRQDKRPMMSDIRESGSIEQDADIVAFLYRDDY 403
Cdd:PRK05636 385 QLMS-SGKRV-ESRQQEVSEFSRQLKLLAKELDVPLIAISQLNRGPESRTDKRPQLADLRESGSLEQDADMVMLLYRPDS 462
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 404 YNRGgdedddddggfepqtNDENGEIEIIIAKQRNGPTGTVKLHFMKQYNKFtdIDYAHA 463
Cdd:PRK05636 463 QDKD---------------DERAGEADIILAKHRGGPIDTVQVAHQLHYSRF--VDMARG 505
|
|
| PRK08006 |
PRK08006 |
replicative DNA helicase DnaB; |
2-455 |
4.99e-134 |
|
replicative DNA helicase DnaB;
Pssm-ID: 181193 [Multi-domain] Cd Length: 471 Bit Score: 394.76 E-value: 4.99e-134
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 2 DRMYEQNQMP-HNNEAEQSVLGSIIIDPELINTTQEVLLPESFYRGAHQHIFRAMMHLNEDNKEIDVVTLMDQLSMEGTL 80
Cdd:PRK08006 18 DPQVAGLKVPpHSIEAEQSVLGGLMLDNERWDDVAERVVADDFYTRPHRHIFTEMARLQESGSPIDLITLAESLERQGQL 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 81 NEAGGPQYLAELSTNVPTTRNVQYYTDIVSKHALKRRLIQTADSIANDGYNDE-LELDAILSDAERRILELSSSRES--D 157
Cdd:PRK08006 98 DSVGGFAYLAELSKNTPSAANISAYADIVRERAVVREMISVANEIADAGYDPQgRTSEDLLDLAESRVFQIAESRANkdE 177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 158 GFKDIRDVLGQVYETAEELDQ--NSGQTpGIPTGYRDLDQMTAGFNRNDLIILAARPSVGKTAFALNIAQKVATHEDMyT 235
Cdd:PRK08006 178 GPKNIADILDATVARIEQLFQqpHDGVT-GVNTGYDDLNKKTAGLQPSDLIIVAARPSMGKTTFAMNLCENAAMLQDK-P 255
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 236 VGIFSLEMGADQLATRMICSSGNVDSNRLRTGTMTEEDWSRFTIAVG-KLSRTKIFIDDTPGIRINDLRSKCRRLKQEH- 313
Cdd:PRK08006 256 VLIFSLEMPGEQIMMRMLASLSRVDQTRIRTGQLDDEDWARISGTMGiLLEKRNMYIDDSSGLTPTEVRSRARRIFREHg 335
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 314 GLDMIVIDYLQLIQGSGsrASDNRQQEVSEISRTLKALARELECPVIALSQLSRGVEQRQDKRPMMSDIRESGSIEQDAD 393
Cdd:PRK08006 336 GLSLIMIDYLQLMRVPS--LSDNRTLEIAEISRSLKALAKELQVPVVALSQLNRSLEQRADKRPVNSDLRESGSIEQDAD 413
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446297788 394 IVAFLYRDDYYNrggdedddddggfepQTNDENGEIEIIIAKQRNGPTGTVKLHFMKQYNKF 455
Cdd:PRK08006 414 LIMFIYRDEVYH---------------ENSDLKGIAEIIIGKQRNGPIGTVRLTFNGQWSRF 460
|
|
| PRK08506 |
PRK08506 |
replicative DNA helicase; Provisional |
1-459 |
7.15e-133 |
|
replicative DNA helicase; Provisional
Pssm-ID: 236278 [Multi-domain] Cd Length: 472 Bit Score: 392.07 E-value: 7.15e-133
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 1 MDRMYEQNqmphnneAEQSVLGSIIIDPELINTTQEVLLPESFYRGAHQHIFRAMMHLNEDNKEIDVVTLMDQLSMEGTL 80
Cdd:PRK08506 1 MDELYDLD-------IERAVLSSILFSPDKFEEIASVLEPKDFYLPAHQDIFEAMLKLHNEDEPIDEEFIRKKLPKDKKI 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 81 NEaggpQYLAE-LSTNvPTTrNVQYYTDIVSKHALKRRLIQTADSIANDGYNDELELDAILSDAERRILELSSSRESDGF 159
Cdd:PRK08506 74 DE----EILLEiLATN-PID-NIEAYVEEIKEKSIKRELLSLANTIPEQAVEEDQKSSDILDEVERELYSITNGSNSEDF 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 160 KDIRDVLGQVYETAEELD--QNSGQTpGIPTGYRDLDQMTAGFNRNDLIILAARPSVGKTAFALNIAQKVAthEDMYTVG 237
Cdd:PRK08506 148 KDSKEVIESTMEHIKKQKrlGNKDII-GLDTGFVELNKMTKGFNKGDLIIIAARPSMGKTTLCLNMALKAL--NQDKGVA 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 238 IFSLEMGADQLATRMICSSGNVDSNRLRTGTMTEEDWSRFTIAVGKLSRTKIFIDDTPGIRINDLRSKCRRLKQEH-GLD 316
Cdd:PRK08506 225 FFSLEMPAEQLMLRMLSAKTSIPLQNLRTGDLDDDEWERLSDACDELSKKKLFVYDSGYVNIHQVRAQLRKLKSQHpEIG 304
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 317 MIVIDYLQLIQGSGSRASdnRQQEVSEISRTLKALARELECPVIALSQLSRGVEQRQDKRPMMSDIRESGSIEQDADIVA 396
Cdd:PRK08506 305 LAVIDYLQLMSGSGNFKD--RHLQISEISRGLKLLARELDIPIIALSQLNRSLESRADKRPMLSDLRESGAIEQDADIIL 382
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 397 FLYRDDYY------NRGGDEDDDDDGGFEPQ-TNDENGEIEIIIAKQRNGPTGTVKLHFMKQYNKFTDID 459
Cdd:PRK08506 383 FVYRDDVYkereekEKEKKAKKEGKEERRIHfQNKSIEEAEIIIGKNRNGPTGTVKLRFQKEFTRFVDKP 452
|
|
| PRK06904 |
PRK06904 |
replicative DNA helicase; Validated |
2-458 |
1.16e-129 |
|
replicative DNA helicase; Validated
Pssm-ID: 136106 [Multi-domain] Cd Length: 472 Bit Score: 383.58 E-value: 1.16e-129
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 2 DRMYEQNQMP-HNNEAEQSVLGSIIIDPELINTTQEVLLPESFYRGAHQHIFRAMMHLNEDNKEIDVVTLMDQLSMEGTL 80
Cdd:PRK06904 14 DKKTAQVLIPpHSIEAEQAVLGGIMLDNRHWDSVAERVIADDFYTFEHRIIFQEMELLFRQNTPIDLLTLDQALKTKGKS 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 81 NEAGGPQYLAELSTNVPTTRNVQYYTDIVSKHALKRRLIQTADSIANDGYNDE-LELDAILSDAERRILELSSSR--ESD 157
Cdd:PRK06904 94 DEVGGFAYLAELSNNTPSAANILAYADIVREKAILRELISVGNNIAKNAYSPKgQDIKDILDEAERDVFSIAEKRttANE 173
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 158 GFKDIRDVLGQVYETAEELDQ---NSGQTpGIPTGYRDLDQMTAGFNRNDLIILAARPSVGKTAFALNIAQKVATHEDMy 234
Cdd:PRK06904 174 GPQNVINLLENTIDKIENLAAtptNNGVT-GVTTGFTDLDKKTAGLQPSDLIIVAARPSMGKTTFAMNLCENAAMASEK- 251
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 235 TVGIFSLEMGADQLATRMICSSGNVDSNRLRTG-TMTEEDWSRFTIAVGKLS-RTKIFIDDTPGIRINDLRSKCRRLKQE 312
Cdd:PRK06904 252 PVLVFSLEMPAEQIMMRMLASLSRVDQTKIRTGqNLDQQDWAKISSTVGMFKqKPNLYIDDSSGLTPTELRSRARRVYRE 331
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 313 HG-LDMIVIDYLQLIQGSGsrASDNRQQEVSEISRTLKALARELECPVIALSQLSRGVEQRQDKRPMMSDIRESGSIEQD 391
Cdd:PRK06904 332 NGgLSLIMVDYLQLMRAPG--FEDNRTLEIAEISRSLKALAKELKVPVVALSQLNRTLENRGDKRPVNSDLRESGSIEQD 409
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446297788 392 ADIVAFLYRDDYYNRGgdedddddggfepqTNDENGEIEIIIAKQRNGPTGTVKLHFMKQYNKFTDI 458
Cdd:PRK06904 410 ADLIMFIYRDEVYNET--------------TEDNKGVAEIIIGKQRNGPIGRVRLAFQGQYSRFDNL 462
|
|
| PRK08840 |
PRK08840 |
replicative DNA helicase; Provisional |
11-455 |
5.19e-129 |
|
replicative DNA helicase; Provisional
Pssm-ID: 181562 [Multi-domain] Cd Length: 464 Bit Score: 381.64 E-value: 5.19e-129
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 11 PHNNEAEQSVLGSIIIDPELINTTQEVLLPESFYRGAHQHIFRAMMHLNEDNKEIDVVTLMDQLSMEGTLNEAGGPQYLA 90
Cdd:PRK08840 21 PHSLEAEQSVIGGLLLDNERWDTVAEKVVASDFYSRPHRLIFEGVKSILEAGKPLDLITLSEHLERREQLEDVGGFAYLA 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 91 ELSTNVPTTRNVQYYTDIVSKHALKRRLIQTADSIANDGYNDELELDAILSD-AERRILELSSSR--ESDGFKDIRDVLG 167
Cdd:PRK08840 101 DLAKNTPSAANINAYADIVAERALVRNLIGVANEIADAGYDPQGRTSEDLLDmAESKVFAIAEARtsENEGPQNVDSILE 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 168 QVYETAEELDQN--SGQTpGIPTGYRDLDQMTAGFNRNDLIILAARPSVGKTAFALNIAQKVATHEDMyTVGIFSLEMGA 245
Cdd:PRK08840 181 KTLERIELLYKTpqDGVT-GVDTGFTDLNKKTAGLQGSDLIIVAARPSMGKTTFAMNLCENAAMDQDK-PVLIFSLEMPA 258
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 246 DQLATRMICSSGNVDSNRLRTGTMTEEDWSRFTIAVGKLSRTK-IFIDDTPGIRINDLRSKCRRLKQEH-GLDMIVIDYL 323
Cdd:PRK08840 259 EQLMMRMLASLSRVDQTKIRTGQLDDEDWARISSTMGILMEKKnMYIDDSSGLTPTEVRSRARRIAREHgGLSMIMVDYL 338
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 324 QLIQGSGsrASDNRQQEVSEISRTLKALARELECPVIALSQLSRGVEQRQDKRPMMSDIRESGSIEQDADIVAFLYRDDY 403
Cdd:PRK08840 339 QLMRVPA--LSDNRTLEIAEISRSLKALAKELNVPVVALSQLNRSLEQRADKRPVNSDLRESGSIEQDADLIMFIYRDEV 416
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|..
gi 446297788 404 YNrggdedddddggfePQTNdENGEIEIIIAKQRNGPTGTVKLHFMKQYNKF 455
Cdd:PRK08840 417 YN--------------PDSP-LKGTAEIIIGKQRNGPIGSVRLTFQGQYSRF 453
|
|
| PRK06321 |
PRK06321 |
replicative DNA helicase; Provisional |
11-455 |
5.90e-120 |
|
replicative DNA helicase; Provisional
Pssm-ID: 180528 [Multi-domain] Cd Length: 472 Bit Score: 358.77 E-value: 5.90e-120
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 11 PHNNEAEQSVLGSIIIDPELINTTQEVLLPESFYRGAHQHIFRAMMHLNEDNKEIDVVTLMDQLSMEGTLNEAGGPQYLA 90
Cdd:PRK06321 17 PNSKESEMIVLGCMLTSVNYLNLAANQLQEDDFYFLEHKIIFRVLQDAFKSDKPIDVHLAGEELKRRNQLNVIGGPSYLI 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 91 ELSTNVPTTRNVQYYTDIVSKHALKRRLIQTADSIANDGYNDELELDAILSDAERRILELSSSRE-------SDGFKDIR 163
Cdd:PRK06321 97 TLAEFAGTSAYIEEYAEIIRSKSILRKMIQTAKEIEKKALEEPKDVATALDEAQNLLFKISQTTNlaqyvlvADKLKGLT 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 164 DVLGQVY----ETAEELDQNSGQTP------GIPTGYRDLDQMTAGFNRNDLIILAARPSVGKTAFALNIAQKVAtHEDM 233
Cdd:PRK06321 177 SSKDKPFllqlQERQEAFQQSAQGDsspmisGIPTHFIDLDKMINGFSPSNLMILAARPAMGKTALALNIAENFC-FQNR 255
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 234 YTVGIFSLEMGADQLATRMICSSGNVDSNRLRTGTMTEEDWSRFTIAVGKLSRTKIFIDDTPGIRINDLRSKCRRLKQEH 313
Cdd:PRK06321 256 LPVGIFSLEMTVDQLIHRIICSRSEVESKKISVGDLSGRDFQRIVSVVNEMQEHTLLIDDQPGLKITDLRARARRMKESY 335
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 314 GLDMIVIDYLQLIQGSGS-RASDNRQQEVSEISRTLKALARELECPVIALSQLSRGVEQRQDKRPMMSDIRESGSIEQDA 392
Cdd:PRK06321 336 DIQFLIIDYLQLLSGSGNlRNSESRQTEISEISRMLKNLARELNIPILCLSQLSRKVEDRANHRPMMSDLRESGSIEQDS 415
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446297788 393 DIVAFLYRDDYYNrggdedddddggfepqTNDENGEIEIIIAKQRNGPTGTVKLHFMKQYNKF 455
Cdd:PRK06321 416 DLVMFLLRREYYD----------------PNDKPGTAELIVAKNRHGSIGSVPLVFEKEFARF 462
|
|
| PRK06749 |
PRK06749 |
replicative DNA helicase; Provisional |
10-457 |
3.32e-115 |
|
replicative DNA helicase; Provisional
Pssm-ID: 168658 [Multi-domain] Cd Length: 428 Bit Score: 345.40 E-value: 3.32e-115
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 10 MPHNNEAEQSVLGSIIIDPELINTTQevLLPESFYRGAHQHIFRAMMHLNEDNKEIDVVTLMDQLSmEGTLNEAGGPQYL 89
Cdd:PRK06749 2 SIQNVEAEKTVLGSLLLDGELIKECR--LTEQYFSMPVHKSIFQLMRKMEDEGQPIDLVTFTSRVD-PNFLKGIGGMEYF 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 90 AELSTNVPTTRNVQYYTDIVSK-----------HALKRRLIQTADsiandgyndelelDAILSDAERRILELSSSRESDG 158
Cdd:PRK06749 79 IGLMDGVPTTSNFSYYEGLVRGawkmyqagvlgHKMGERLIAEKS-------------EKIIGETITALCELEEKDCVCE 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 159 FkDIRDVLGQVYEtaeELDQNSGQTPGIPTGYRDLDQMTAGFNRNDLIILAARPSVGKTAFALNIAQKVATHEDmyTVGI 238
Cdd:PRK06749 146 F-DLKDALVDLYE---ELHQDAKEITGIETGYTSLNKMTCGLQEGDFVVLGARPSMGKTAFALNVGLHAAKSGA--AVGL 219
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 239 FSLEMGADQLATRMICSSGNVDSNRLRTGT--MTEEDWSRFTIAVGKLSRTKIFIDDTPGIRINDLRSKCRRLKQEHGLD 316
Cdd:PRK06749 220 FSLEMSSKQLLKRMASCVGEVSGGRLKNPKhrFAMEDWEKVSKAFAEIGELPLEIYDNAGVTVQDIWMQTRKLKRKHGDK 299
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 317 --MIVIDYLQLIQGSgSRASDNRQQEVSEISRTLKALARELECPVIALSQLSRGVEQRQDKRPMMSDIRESGSIEQDADI 394
Cdd:PRK06749 300 kiLIIVDYLQLITGD-PKHKGNRFQEISEISRKLKLLARELNVCVVALSQLSRSVESRQDKRPLLSDLRETGQIEQDADV 378
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446297788 395 VAFLYRDDYYNRGGdedddddggfepqtndENGEI-EIIIAKQRNGPTGTVKLHFMKQYNKFTD 457
Cdd:PRK06749 379 IMLMYREDYYDKET----------------MQKEMtEIHVAKHRNGPVGSFKLRFLKEFGRFVE 426
|
|
| DnaB |
pfam00772 |
DnaB-like helicase N terminal domain; The hexameric helicase DnaB unwinds the DNA duplex at ... |
9-109 |
7.01e-37 |
|
DnaB-like helicase N terminal domain; The hexameric helicase DnaB unwinds the DNA duplex at the Escherichia coli chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a change in the quaternary structure of the protein involving dimerization of the N-terminal domain has been observed and may occur during the enzymatic cycle. This N-terminal domain is required both for interaction with other proteins in the primosome and for DnaB helicase activity.
Pssm-ID: 395624 [Multi-domain] Cd Length: 103 Bit Score: 130.82 E-value: 7.01e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 9 QMPHNNEAEQSVLGSIIIDPELINTTQEVLLPESFYRGAHQHIFRAMMHLNEDNKEIDVVTLMDQLSMEGTLNEAGGPQY 88
Cdd:pfam00772 1 VPPHNIEAEQAVLGALLLDPEAIDEVADILKPEDFYDPAHRLIFEAILDLYDKGEPIDPVTVAEELEKKGKLEDVGGIAY 80
|
90 100
....*....|....*....|.
gi 446297788 89 LAELSTNVPTTRNVQYYTDIV 109
Cdd:pfam00772 81 LAELAANVPSAANIEYYARIV 101
|
|
| PRK07773 |
PRK07773 |
replicative DNA helicase; Validated |
381-458 |
1.59e-16 |
|
replicative DNA helicase; Validated
Pssm-ID: 236093 [Multi-domain] Cd Length: 886 Bit Score: 82.49 E-value: 1.59e-16
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446297788 381 DIRESGSIEQDADIVAFLYRDDYYNRGgdedddddggfepqtNDENGEIEIIIAKQRNGPTGTVKLHFMKQYNKFTDI 458
Cdd:PRK07773 821 GIIVHNSIEQDADVVILLYRPDYYDRD---------------DPRGGEAEFIVAKHRNGPTGTVTLAFQLHLSRFANL 883
|
|
| RecA-like_Gp4D_helicase |
cd19483 |
RecA-like domain of Escherichia coli bacteriophage T7 Gp4D helicase; This family includes the ... |
206-395 |
5.41e-16 |
|
RecA-like domain of Escherichia coli bacteriophage T7 Gp4D helicase; This family includes the RecA-like domain of the Gp4D fragment of the Gene4 helicase-primase (Gp4) from bacteriophage T7. Gp4D (residues 241-566) is the minimal fragment of the Gp4 that forms hexameric rings, it contains the helicase domain and the linker connecting the helicase and primase domains. Helicases are ring-shaped oligomeric enzymes that unwind DNA at the replication fork; they couple NTP hydrolysis to the unwinding of nucleic acid duplexes into their component strands. This family belongs to the RecA-like NTPase superfamily which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410891 [Multi-domain] Cd Length: 231 Bit Score: 76.84 E-value: 5.41e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 206 IILAARPSVGKTAFALNIAQKVATHEDmYTVGIFSLEMGADQLATRMICSSGNVDSNRLRTG---TMTEEDWSRFTIAV- 281
Cdd:cd19483 1 VTIGAGSGIGKSTIVRELAYHLITEHG-EKVGIISLEESVEETAKGLAGKHLGKPEPLELPRddiTEEEEDDAFDNELGs 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 282 GKLsrtkIFIDDTPGIRINDLRSKCRRLKQEHGLDMIVIDYLQLIqGSGSRASDNRqQEVSEISRTLKALARELECPVIA 361
Cdd:cd19483 80 GRF----FLYDHFGSLDWDNLKEKIRYMVKVLGCKVIVLDHLTIL-VSGLDSSDER-KELDEIMTELAALVKELGVTIIL 153
|
170 180 190
....*....|....*....|....*....|....*..
gi 446297788 362 LSQLSR---GVEQRQDKRPMMSDIRESGSIEQDADIV 395
Cdd:cd19483 154 VSHLRRpggGKGHEEGGEVSESDLRGSSAIAQLSDYV 190
|
|
| AAA_25 |
pfam13481 |
AAA domain; This AAA domain is found in a wide variety of presumed DNA repair proteins. |
205-368 |
2.05e-10 |
|
AAA domain; This AAA domain is found in a wide variety of presumed DNA repair proteins.
Pssm-ID: 463892 [Multi-domain] Cd Length: 193 Bit Score: 60.09 E-value: 2.05e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 205 LIILAARPSVGKTAFALNIAQKVAT-----HEDMYTVG----IFSLEMGADQLATRMICSSGNVDSNRlrtgtmteedws 275
Cdd:pfam13481 35 LGLLAGAPGTGKTTLALDLAAAVATgkpwlGGPRVPEQgkvlYVSAEGPADELRRRLRAAGADLDLPA------------ 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 276 RFTIAVGKLSRTKIFIDDTPGIRINDLRSKCRRLKQEHGLDMIVIDYLQliqgSGSRASDNRQQEVSEISRTLKALAREL 355
Cdd:pfam13481 103 RLLFLSLVESLPLFFLDRGGPLLDADVDALEAALEEVEDPDLVVIDPLA----RALGGDENSNSDVGRLVKALDRLARRT 178
|
170
....*....|...
gi 446297788 356 ECPVIALSQLSRG 368
Cdd:pfam13481 179 GATVLLVHHVGKD 191
|
|
| RepA |
COG3598 |
RecA-family ATPase [Replication, recombination and repair]; |
202-402 |
1.07e-09 |
|
RecA-family ATPase [Replication, recombination and repair];
Pssm-ID: 442817 [Multi-domain] Cd Length: 313 Bit Score: 59.53 E-value: 1.07e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 202 RNDLIILAARPSVGKTAFALNIAQKVATHEDMY-------TVGIFSLEMGADQLATRMicssgnvdsNRLRT--GTMTEE 272
Cdd:COG3598 12 EGGVTLLAGPPGTGKSFLALQLAAAVAAGGPWLgrrvppgKVLYLAAEDDRGELRRRL---------KALGAdlGLPFAD 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 273 DWSRFTIavgkLSRTKIFIDDtpgiriNDLRSKCRRLKQEhGLDMIVIDYLQ-LIQGsgsraSDNRQQEVSEISRTLKAL 351
Cdd:COG3598 83 LDGRLRL----LSLAGDLDDT------DDLEALERAIEEE-GPDLVVIDPLArVFGG-----DENDAEEMRAFLNPLDRL 146
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 446297788 352 ARELECPVIALSQLSRGveqrQDKRPMMSDIRESGSIEQDADIVAFLYRDD 402
Cdd:COG3598 147 AERTGAAVLLVHHTGKG----GAGKDSGDRARGSSALRGAARSVLVLSREK 193
|
|
| PRK05973 |
PRK05973 |
replicative DNA helicase; Provisional |
204-383 |
4.83e-09 |
|
replicative DNA helicase; Provisional
Pssm-ID: 168322 [Multi-domain] Cd Length: 237 Bit Score: 56.58 E-value: 4.83e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 204 DLIILAARPSVGKTAFALNIAqkVATHEDMYTVGIFSLEMGADQLATRmicssgnvdsnrLRTgtmteedwsrftIAVGK 283
Cdd:PRK05973 65 DLVLLGARPGHGKTLLGLELA--VEAMKSGRTGVFFTLEYTEQDVRDR------------LRA------------LGADR 118
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 284 LSRTKIFIDDTPgiriNDLRSK--CRRLKQEHGLDMIVIDYLQLIqgsgsrasDNRQQ--EVSEISRTLKALARELECPV 359
Cdd:PRK05973 119 AQFADLFEFDTS----DAICADyiIARLASAPRGTLVVIDYLQLL--------DQRREkpDLSVQVRALKSFARERGLII 186
|
170 180
....*....|....*....|....
gi 446297788 360 IALSQLSRGVEQRQDKRPMMSDIR 383
Cdd:PRK05973 187 VFISQIDRSFDPSAKPLPDIRDVR 210
|
|
| 41 |
PHA02542 |
41 helicase; Provisional |
17-393 |
7.71e-08 |
|
41 helicase; Provisional
Pssm-ID: 222864 [Multi-domain] Cd Length: 473 Bit Score: 54.68 E-value: 7.71e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 17 EQSVLGSIIIDPELINTTQEVLLPESFYRGAHQHIFRAMM-HLNEDNKEIDVVTL---MDQLSM-EGTLNEAggPQYLAE 91
Cdd:PHA02542 2 EETILSNLIFNEDYFRKVWPYLKAEYFESGPEKVIFKLIKkHVNEYNAIPTIEALsiaLENRSLsEVTFDGA--KDLLSS 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 92 LSTNVPttrNVQYYTDIVSKHALKR---RLIQTADSIANDG-------YNDELELDAI---LSDAerrileLSSSRESDg 158
Cdd:PHA02542 80 LSDNPE---DLDWLVKETEKWCQDRamyNALSKAIEIQDNAdkplekrNKKLPDVGAIpdiMQEA------LAISFDSS- 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 159 fkdirdvLGQVY-ETAEE-LDQNSGQTPGIPTGYRDLDQMT-AGFNRNDLIILAARPSVGKTAFALNIAQkvATHEDMYT 235
Cdd:PHA02542 150 -------VGHDYfEDYEErYDSYQSKANKIPFKLEILNKITkGGAERKTLNVLLAGVNVGKSLGLCSLAA--DYLQQGYN 220
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 236 VGIFSLEMGADQLATRmicssgnVDSNRLRTgTMTEED---WSRFTIAVGKLSRT---KIFIDDTP--GIRINDLRSKCR 307
Cdd:PHA02542 221 VLYISMEMAEEVIAKR-------IDANLLDV-SLDDIDdlsKAEYKAKMEKLRSKtqgKLIIKQYPtgGAHAGHFRALLN 292
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 308 RLKQEHGL--DMIVIDYLQLIQGSGSR-ASDNRQQEVSEISRTLKALARELECPVIALSQLSRGVEQRQDkrPMMSDIRE 384
Cdd:PHA02542 293 ELKLKKNFkpDVIIVDYLGICASSRLRvSSENSYTYVKAIAEELRGLAVEHDVVVWTAAQTTRSGWDSSD--VDMSDTAE 370
|
....*....
gi 446297788 385 SGSIEQDAD 393
Cdd:PHA02542 371 SAGLPATAD 379
|
|
| RAD55 |
COG0467 |
RecA-superfamily ATPase, KaiC/GvpD/RAD55 family [Signal transduction mechanisms]; |
186-406 |
1.03e-06 |
|
RecA-superfamily ATPase, KaiC/GvpD/RAD55 family [Signal transduction mechanisms];
Pssm-ID: 440235 [Multi-domain] Cd Length: 221 Bit Score: 49.53 E-value: 1.03e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 186 IPTGYRDLDQMTA-GFNRNDLIILAARPSVGKTAFALNIAQKVAthEDMYTVGIFSLEMGADQLATRMicSSGNVDSNRL 264
Cdd:COG0467 2 VPTGIPGLDELLGgGLPRGSSTLLSGPPGTGKTTLALQFLAEGL--RRGEKGLYVSFEESPEQLLRRA--ESLGLDLEEY 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 265 rtgtmteedwsrftIAVGKLsrtkIFIDDTP---GIRINDLRSKCRRLKQEHGLDMIVIDYLqliqgSGSRASDNRQQEV 341
Cdd:COG0467 78 --------------IESGLL----RIIDLSPeelGLDLEELLARLREAVEEFGAKRVVIDSL-----SGLLLALPDPERL 134
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 446297788 342 SEISRTLKALARELECPVIALSQLsrgveqrqdkrPMMSDIRESGSIEQDADIVAFLYRDDYYNR 406
Cdd:COG0467 135 REFLHRLLRYLKKRGVTTLLTSET-----------GGLEDEATEGGLSYLADGVILLRYVELGGE 188
|
|
| RecA-like_superfamily |
cd01120 |
RecA-like_NTPases; RecA-like NTPases. This superfamily includes the NTP binding domain of F1 ... |
301-389 |
6.21e-06 |
|
RecA-like_NTPases; RecA-like NTPases. This superfamily includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410865 [Multi-domain] Cd Length: 119 Bit Score: 45.19 E-value: 6.21e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 301 DLRSKCRRLKQEHGLDMIVIDYLQLIqgsGSRASDNRQQEVSEISRTLKALARELECPVIALSQLSRGVEqrqDKRPMMS 380
Cdd:cd01120 37 TILEAIEDLIEEKKLDIIIIDSLSSL---ARASQGDRSSELLEDLAKLLRAARNTGITVIATIHSDKFDI---DRGGSSN 110
|
....*....
gi 446297788 381 DIRESGSIE 389
Cdd:cd01120 111 DERLLKSLR 119
|
|
| KaiC-like |
cd01124 |
Circadian Clock Protein KaiC; KaiC is a circadian clock protein, most studied in cyanobacteria. ... |
186-366 |
8.36e-05 |
|
Circadian Clock Protein KaiC; KaiC is a circadian clock protein, most studied in cyanobacteria. KaiC, an autokinase, autophosphatase, and ATPase, is part of the core oscillator, composed of three proteins: KaiA, KaiB, and KaiC. The circadian oscillation is regulated via KaiC phosphorylation.
Pssm-ID: 410869 [Multi-domain] Cd Length: 222 Bit Score: 43.79 E-value: 8.36e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 186 IPTGYRDLDQMT-AGFNRNDLIILAARPSVGKTAFALNIAQKVATHEDmyTVGIFSLEMGADQLATRMicssgnvdsnrL 264
Cdd:cd01124 1 VKTGIPGLDELLgGGIPKGSVTLLTGGPGTGKTLFGLQFLYAGAKNGE--PGLFFTFEESPERLLRNA-----------K 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446297788 265 RTGTmteeDWSRFTIaVGKLSRTKIFIDDTPGIRINDLRSKCRRLKQEHGLDMIVIDYLQLIQgsgSRASDNRQQEvsEI 344
Cdd:cd01124 68 SFGW----DFDEMED-EGKLIIVDAPPTEAGRFSLDELLSRILSIIKSFKAKRVVIDSLSGLR---RAKEDQMRAR--RI 137
|
170 180
....*....|....*....|..
gi 446297788 345 SRTLKALARELECPVIALSQLS 366
Cdd:cd01124 138 VIALLNELRAAGVTTIFTSEMR 159
|
|
| |
