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Conserved domains on  [gi|446267479|ref|WP_000345334|]
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MULTISPECIES: sulfite exporter TauE/SafE family protein [Salmonella]

Protein Classification

sulfite exporter TauE/SafE family protein( domain architecture ID 10002314)

sulfite exporter TauE/SafE family protein is an inner membrane anion permease involved in the transport of anions across the cytoplasmic membrane during taurine metabolism as an exporter of sulfoacetate

Gene Ontology:  GO:0016020|GO:0006810
PubMed:  22192777
TCDB:  2.A.102

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
TauE COG0730
Sulfite exporter TauE/SafE/YfcA and related permeases, UPF0721 family [Inorganic ion transport ...
19-256 5.23e-21

Sulfite exporter TauE/SafE/YfcA and related permeases, UPF0721 family [Inorganic ion transport and metabolism];


:

Pssm-ID: 440494  Cd Length: 250  Bit Score: 89.48  E-value: 5.23e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446267479  19 IYTVIALMFLYTFVGICAGFGGGLTTMPLITLM-LPVKMATPLSVIVGTATAIYATWLSRKE--TDWRSAAVLIGFSFLG 95
Cdd:COG0730    4 LLLLLLAGFLAGFLDGLLGVGGGLITVPALLLFgLPPAVAVGTSLLAVVFTSLSGALAHRRRgnVDWRLLLPLALGALIG 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446267479  96 IPVGLYALSYLPDHIMKIGLGGFLILYSFYSMFIPRLPIYDRRWIAAPLGAIAGALGAA-------FSTNGPPVVMYGML 168
Cdd:COG0730   84 ALLGALLLLLLPADVLKLLFGVLLLLVALLMLLRPKPGAEPERRLPRRSPLLLLLLGFVigflsglFGIGGGFLLVPALV 163
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446267479 169 R--NLGPAAFRGTLNAFFTANNIAVVGGLATSGILtisTFKLVIFCIPTMILGSLVGQYVHKRISVKVFRVLVFLLLIAS 246
Cdd:COG0730  164 LllGLPLKRAVATSLALIFVTALAGLIGFALLGYV---DWPLALLLALGSLLGAYLGARLARRLPPKLLRRLFAVVLLLV 240
                        250
                 ....*....|
gi 446267479 247 GAMLIKGALG 256
Cdd:COG0730  241 GLKLLLKALG 250
 
Name Accession Description Interval E-value
TauE COG0730
Sulfite exporter TauE/SafE/YfcA and related permeases, UPF0721 family [Inorganic ion transport ...
19-256 5.23e-21

Sulfite exporter TauE/SafE/YfcA and related permeases, UPF0721 family [Inorganic ion transport and metabolism];


Pssm-ID: 440494  Cd Length: 250  Bit Score: 89.48  E-value: 5.23e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446267479  19 IYTVIALMFLYTFVGICAGFGGGLTTMPLITLM-LPVKMATPLSVIVGTATAIYATWLSRKE--TDWRSAAVLIGFSFLG 95
Cdd:COG0730    4 LLLLLLAGFLAGFLDGLLGVGGGLITVPALLLFgLPPAVAVGTSLLAVVFTSLSGALAHRRRgnVDWRLLLPLALGALIG 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446267479  96 IPVGLYALSYLPDHIMKIGLGGFLILYSFYSMFIPRLPIYDRRWIAAPLGAIAGALGAA-------FSTNGPPVVMYGML 168
Cdd:COG0730   84 ALLGALLLLLLPADVLKLLFGVLLLLVALLMLLRPKPGAEPERRLPRRSPLLLLLLGFVigflsglFGIGGGFLLVPALV 163
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446267479 169 R--NLGPAAFRGTLNAFFTANNIAVVGGLATSGILtisTFKLVIFCIPTMILGSLVGQYVHKRISVKVFRVLVFLLLIAS 246
Cdd:COG0730  164 LllGLPLKRAVATSLALIFVTALAGLIGFALLGYV---DWPLALLLALGSLLGAYLGARLARRLPPKLLRRLFAVVLLLV 240
                        250
                 ....*....|
gi 446267479 247 GAMLIKGALG 256
Cdd:COG0730  241 GLKLLLKALG 250
TauE pfam01925
Sulfite exporter TauE/SafE; This is a family of integral membrane proteins where the alignment ...
23-248 5.00e-17

Sulfite exporter TauE/SafE; This is a family of integral membrane proteins where the alignment appears to contain two duplicated modules of three transmembrane helices. The proteins are involved in the transport of anions across the cytoplasmic membrane during taurine metabolism as an exporter of sulfoacetate. This family used to be known as DUF81.


Pssm-ID: 460386  Cd Length: 235  Bit Score: 78.39  E-value: 5.00e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446267479   23 IALMFLYTFVGICAGFGGGLTTMPLITLMLPVKMATPLSVIVGTATAIYATWLSRKE--TDWRSAAVLIGFSFLGIPVGL 100
Cdd:pfam01925   1 LLAGLLAGFVGGLLGFGGGLIAVPLLLLLLPPAVAVGTSLLAAVATSLSGALAHRRRgaVDWRLLLRLLLGGLIGALLGA 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446267479  101 YALSYLPDHIMKIGLGGFLILYSFYSMFIPRLPIYDRRWIAAPLGAIAGALGAA-------FSTNGPPVVMYGM--LRNL 171
Cdd:pfam01925  81 LLLLLLPEALLKLLFGVLLLLAALLMLLRRRLGAAPRARRRRPGPLALALLGGLigflsglFGIGGGFLLVPALlyLLGL 160
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446267479  172 GPAAFRGTLNAFFTANNIAVVGGLATSGILtisTFKLVIFCIPTMILGSLVGQYVHKRISVKVFRVLVFLLLIASGA 248
Cdd:pfam01925 161 PLKKAVGTSLLLFLVSNLAALLGYALLGAV---DWPLLLLLLLGALLGAYLGARLARRLPPRLLRRLFAVLLLLVGL 234
 
Name Accession Description Interval E-value
TauE COG0730
Sulfite exporter TauE/SafE/YfcA and related permeases, UPF0721 family [Inorganic ion transport ...
19-256 5.23e-21

Sulfite exporter TauE/SafE/YfcA and related permeases, UPF0721 family [Inorganic ion transport and metabolism];


Pssm-ID: 440494  Cd Length: 250  Bit Score: 89.48  E-value: 5.23e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446267479  19 IYTVIALMFLYTFVGICAGFGGGLTTMPLITLM-LPVKMATPLSVIVGTATAIYATWLSRKE--TDWRSAAVLIGFSFLG 95
Cdd:COG0730    4 LLLLLLAGFLAGFLDGLLGVGGGLITVPALLLFgLPPAVAVGTSLLAVVFTSLSGALAHRRRgnVDWRLLLPLALGALIG 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446267479  96 IPVGLYALSYLPDHIMKIGLGGFLILYSFYSMFIPRLPIYDRRWIAAPLGAIAGALGAA-------FSTNGPPVVMYGML 168
Cdd:COG0730   84 ALLGALLLLLLPADVLKLLFGVLLLLVALLMLLRPKPGAEPERRLPRRSPLLLLLLGFVigflsglFGIGGGFLLVPALV 163
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446267479 169 R--NLGPAAFRGTLNAFFTANNIAVVGGLATSGILtisTFKLVIFCIPTMILGSLVGQYVHKRISVKVFRVLVFLLLIAS 246
Cdd:COG0730  164 LllGLPLKRAVATSLALIFVTALAGLIGFALLGYV---DWPLALLLALGSLLGAYLGARLARRLPPKLLRRLFAVVLLLV 240
                        250
                 ....*....|
gi 446267479 247 GAMLIKGALG 256
Cdd:COG0730  241 GLKLLLKALG 250
TauE pfam01925
Sulfite exporter TauE/SafE; This is a family of integral membrane proteins where the alignment ...
23-248 5.00e-17

Sulfite exporter TauE/SafE; This is a family of integral membrane proteins where the alignment appears to contain two duplicated modules of three transmembrane helices. The proteins are involved in the transport of anions across the cytoplasmic membrane during taurine metabolism as an exporter of sulfoacetate. This family used to be known as DUF81.


Pssm-ID: 460386  Cd Length: 235  Bit Score: 78.39  E-value: 5.00e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446267479   23 IALMFLYTFVGICAGFGGGLTTMPLITLMLPVKMATPLSVIVGTATAIYATWLSRKE--TDWRSAAVLIGFSFLGIPVGL 100
Cdd:pfam01925   1 LLAGLLAGFVGGLLGFGGGLIAVPLLLLLLPPAVAVGTSLLAAVATSLSGALAHRRRgaVDWRLLLRLLLGGLIGALLGA 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446267479  101 YALSYLPDHIMKIGLGGFLILYSFYSMFIPRLPIYDRRWIAAPLGAIAGALGAA-------FSTNGPPVVMYGM--LRNL 171
Cdd:pfam01925  81 LLLLLLPEALLKLLFGVLLLLAALLMLLRRRLGAAPRARRRRPGPLALALLGGLigflsglFGIGGGFLLVPALlyLLGL 160
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446267479  172 GPAAFRGTLNAFFTANNIAVVGGLATSGILtisTFKLVIFCIPTMILGSLVGQYVHKRISVKVFRVLVFLLLIASGA 248
Cdd:pfam01925 161 PLKKAVGTSLLLFLVSNLAALLGYALLGAV---DWPLLLLLLLGALLGAYLGARLARRLPPRLLRRLFAVLLLLVGL 234
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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