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Conserved domains on  [gi|446204314|ref|WP_000282169|]
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MULTISPECIES: queuosine precursor transporter [Staphylococcus]

Protein Classification

VUT family protein( domain architecture ID 10004447)

uncharacterized VUT (Vitamin Uptake Transporter) family protein similar to Escherichia coli inner membrane protein YhhQ, which is Involved in 7-cyanodeazaguanine (preQ0) transport.

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
YhhQ COG1738
Queuosine precursor transporter YhhQ, DUF165 family [Translation, ribosomal structure and ...
20-224 4.35e-58

Queuosine precursor transporter YhhQ, DUF165 family [Translation, ribosomal structure and biogenesis];


:

Pssm-ID: 441344  Cd Length: 220  Bit Score: 183.13  E-value: 4.35e-58
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446204314  20 LMYRFFGKQGLIAWVAIGTIIANIQVIKTVEIFG-ISATLGNVMFASIYLATDILNDIYGRRVAKRAVWLGFSSTLIMII 98
Cdd:COG1738    6 AYRKTRGLIGLAALFVTVLILSNILVQKLVSLFGgFVLTAGAFLFPLTFLATDILTEVYGKKAARRVVWLGFLANLLASL 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446204314  99 VMQLSLHFIPAPEDMAQKALHAIFDVVPRIALGSIVAYIIGQHIDVFIFSLIKKVFsSDKTFFIRAYGSTFLSSIIDTAI 178
Cdd:COG1738   86 LIQLALLLPPAPFWTGQEAFEAVFGFVPRIVLASLLAYLVGQLLDVYVFHRLKKRT-GGKHLWLRNNGSTLVSQLIDTLI 164
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 446204314 179 FVAIAFIGSLPGTVVFEIFITTYVLKLASTVFNVPFGYIAKSFYRK 224
Cdd:COG1738  165 FFTIAFYGVFPWEVLLEIILSQYLFKLLVALLDTPFTYLVVRWLKR 210
 
Name Accession Description Interval E-value
YhhQ COG1738
Queuosine precursor transporter YhhQ, DUF165 family [Translation, ribosomal structure and ...
20-224 4.35e-58

Queuosine precursor transporter YhhQ, DUF165 family [Translation, ribosomal structure and biogenesis];


Pssm-ID: 441344  Cd Length: 220  Bit Score: 183.13  E-value: 4.35e-58
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446204314  20 LMYRFFGKQGLIAWVAIGTIIANIQVIKTVEIFG-ISATLGNVMFASIYLATDILNDIYGRRVAKRAVWLGFSSTLIMII 98
Cdd:COG1738    6 AYRKTRGLIGLAALFVTVLILSNILVQKLVSLFGgFVLTAGAFLFPLTFLATDILTEVYGKKAARRVVWLGFLANLLASL 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446204314  99 VMQLSLHFIPAPEDMAQKALHAIFDVVPRIALGSIVAYIIGQHIDVFIFSLIKKVFsSDKTFFIRAYGSTFLSSIIDTAI 178
Cdd:COG1738   86 LIQLALLLPPAPFWTGQEAFEAVFGFVPRIVLASLLAYLVGQLLDVYVFHRLKKRT-GGKHLWLRNNGSTLVSQLIDTLI 164
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 446204314 179 FVAIAFIGSLPGTVVFEIFITTYVLKLASTVFNVPFGYIAKSFYRK 224
Cdd:COG1738  165 FFTIAFYGVFPWEVLLEIILSQYLFKLLVALLDTPFTYLVVRWLKR 210
TIGR00697 TIGR00697
conserved hypothetical integral membrane protein; All known members of this family are ...
25-224 4.94e-49

conserved hypothetical integral membrane protein; All known members of this family are proteins or 210-250 amino acids in length. Conserved regions of hydrophobicity suggest that all members of the family are integral membrane proteins. [Hypothetical proteins, Conserved]


Pssm-ID: 129780  Cd Length: 202  Bit Score: 159.43  E-value: 4.94e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446204314   25 FGKQGLIAWVAIGTIIANIQVIKTVEIFGISATLGNVMFASIYLATDILNDIYGRRVAKRAVWLGFSSTLIMIIVMQLSL 104
Cdd:TIGR00697   1 RGKIWLSAWHSLAIIIANYFVLKPITLFGFEVTWGNVYYPGTFLATDVLREIYGKKDARKAIFVGFISALLFSVLTQLHL 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446204314  105 HFIPAPEDMAQKALHAIFDVVPRIALGSIVAYIIGQHIDVFIFSLIKKVFSSdKTFFIRAYGSTFLSSIIDTAIFVAIAF 184
Cdd:TIGR00697  81 FFIPSPGDESQTHFEALFSSSPRIALASLVAYIVSQLLDVKVFTFLKKRTPG-RFLWLRSNGSTLFSQLIDTFIFSFIAF 159
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 446204314  185 IGS--LPGTVVFEIFITTYVLKLASTVFNVPFGYIAKSFYRK 224
Cdd:TIGR00697 160 YGSppFPAENLLNIMIFSYLIKGTIGVLATPPVYLAKLNILR 201
Vut_1 pfam02592
Putative vitamin uptake transporter;
57-218 5.66e-41

Putative vitamin uptake transporter;


Pssm-ID: 460607  Cd Length: 154  Bit Score: 137.22  E-value: 5.66e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446204314   57 TLGNVMFASIYLATDILNDIYGRRVAKRAVWLGFSSTLIMIIVMQLSLHFIPAPEdmaQKALHAIFDVVPRIALGSIVAY 136
Cdd:pfam02592   1 TAGVLLFPLTFLLTDILTEVYGKKAARRAIWLGFLANLLAVLLIQLALLLPPPFF---QEAFEAVFGLTPRIVLASLIAY 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446204314  137 IIGQHIDVFIFSLIKKvFSSDKTFFIRAYGSTFLSSIIDTAIFVAIAFigslPGTVVFEIFITTYVLKLASTVFNVPFGY 216
Cdd:pfam02592  78 LVSQLLDVYVFHRLKK-RTGGKHLWLRNNGSTLVSQLIDTLIFITIAF----PAEVILEIILSQYLFKLLVALLDTPFTY 152

                  ..
gi 446204314  217 IA 218
Cdd:pfam02592 153 LV 154
PRK11212 PRK11212
7-cyano-7-deazaguanine/7-aminomethyl-7-deazaguanine transporter;
39-184 2.54e-10

7-cyano-7-deazaguanine/7-aminomethyl-7-deazaguanine transporter;


Pssm-ID: 183041  Cd Length: 210  Bit Score: 58.02  E-value: 2.54e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446204314  39 IIANIQVIKTVEIFGISATLGNVMFASIYLATDILNDIYGRRVAKRAVWLGFSSTLIMIIVMQLSLHfipAPEDMAQKAL 118
Cdd:PRK11212  25 TSSNYLVQLPFTIFGFHTTWGAFSFPFIFLATDLTVRIFGAPLARRIIFAVMLPALLISYVISVLFY---QGSWQGFAAL 101
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446204314 119 HAIFDVVPRIALGSIVAYIIGQHIDVFIFSLIKKVfssdKTFFIRAYGSTFLSSIIDTAIFVAIAF 184
Cdd:PRK11212 102 AEFNLFVARIALASFMAYVLGQILDVHVFNRLRQS----RAWWVAPTASTLFGNLSDTLAFFFIAF 163
 
Name Accession Description Interval E-value
YhhQ COG1738
Queuosine precursor transporter YhhQ, DUF165 family [Translation, ribosomal structure and ...
20-224 4.35e-58

Queuosine precursor transporter YhhQ, DUF165 family [Translation, ribosomal structure and biogenesis];


Pssm-ID: 441344  Cd Length: 220  Bit Score: 183.13  E-value: 4.35e-58
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446204314  20 LMYRFFGKQGLIAWVAIGTIIANIQVIKTVEIFG-ISATLGNVMFASIYLATDILNDIYGRRVAKRAVWLGFSSTLIMII 98
Cdd:COG1738    6 AYRKTRGLIGLAALFVTVLILSNILVQKLVSLFGgFVLTAGAFLFPLTFLATDILTEVYGKKAARRVVWLGFLANLLASL 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446204314  99 VMQLSLHFIPAPEDMAQKALHAIFDVVPRIALGSIVAYIIGQHIDVFIFSLIKKVFsSDKTFFIRAYGSTFLSSIIDTAI 178
Cdd:COG1738   86 LIQLALLLPPAPFWTGQEAFEAVFGFVPRIVLASLLAYLVGQLLDVYVFHRLKKRT-GGKHLWLRNNGSTLVSQLIDTLI 164
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 446204314 179 FVAIAFIGSLPGTVVFEIFITTYVLKLASTVFNVPFGYIAKSFYRK 224
Cdd:COG1738  165 FFTIAFYGVFPWEVLLEIILSQYLFKLLVALLDTPFTYLVVRWLKR 210
TIGR00697 TIGR00697
conserved hypothetical integral membrane protein; All known members of this family are ...
25-224 4.94e-49

conserved hypothetical integral membrane protein; All known members of this family are proteins or 210-250 amino acids in length. Conserved regions of hydrophobicity suggest that all members of the family are integral membrane proteins. [Hypothetical proteins, Conserved]


Pssm-ID: 129780  Cd Length: 202  Bit Score: 159.43  E-value: 4.94e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446204314   25 FGKQGLIAWVAIGTIIANIQVIKTVEIFGISATLGNVMFASIYLATDILNDIYGRRVAKRAVWLGFSSTLIMIIVMQLSL 104
Cdd:TIGR00697   1 RGKIWLSAWHSLAIIIANYFVLKPITLFGFEVTWGNVYYPGTFLATDVLREIYGKKDARKAIFVGFISALLFSVLTQLHL 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446204314  105 HFIPAPEDMAQKALHAIFDVVPRIALGSIVAYIIGQHIDVFIFSLIKKVFSSdKTFFIRAYGSTFLSSIIDTAIFVAIAF 184
Cdd:TIGR00697  81 FFIPSPGDESQTHFEALFSSSPRIALASLVAYIVSQLLDVKVFTFLKKRTPG-RFLWLRSNGSTLFSQLIDTFIFSFIAF 159
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|..
gi 446204314  185 IGS--LPGTVVFEIFITTYVLKLASTVFNVPFGYIAKSFYRK 224
Cdd:TIGR00697 160 YGSppFPAENLLNIMIFSYLIKGTIGVLATPPVYLAKLNILR 201
Vut_1 pfam02592
Putative vitamin uptake transporter;
57-218 5.66e-41

Putative vitamin uptake transporter;


Pssm-ID: 460607  Cd Length: 154  Bit Score: 137.22  E-value: 5.66e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446204314   57 TLGNVMFASIYLATDILNDIYGRRVAKRAVWLGFSSTLIMIIVMQLSLHFIPAPEdmaQKALHAIFDVVPRIALGSIVAY 136
Cdd:pfam02592   1 TAGVLLFPLTFLLTDILTEVYGKKAARRAIWLGFLANLLAVLLIQLALLLPPPFF---QEAFEAVFGLTPRIVLASLIAY 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446204314  137 IIGQHIDVFIFSLIKKvFSSDKTFFIRAYGSTFLSSIIDTAIFVAIAFigslPGTVVFEIFITTYVLKLASTVFNVPFGY 216
Cdd:pfam02592  78 LVSQLLDVYVFHRLKK-RTGGKHLWLRNNGSTLVSQLIDTLIFITIAF----PAEVILEIILSQYLFKLLVALLDTPFTY 152

                  ..
gi 446204314  217 IA 218
Cdd:pfam02592 153 LV 154
PRK11212 PRK11212
7-cyano-7-deazaguanine/7-aminomethyl-7-deazaguanine transporter;
39-184 2.54e-10

7-cyano-7-deazaguanine/7-aminomethyl-7-deazaguanine transporter;


Pssm-ID: 183041  Cd Length: 210  Bit Score: 58.02  E-value: 2.54e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446204314  39 IIANIQVIKTVEIFGISATLGNVMFASIYLATDILNDIYGRRVAKRAVWLGFSSTLIMIIVMQLSLHfipAPEDMAQKAL 118
Cdd:PRK11212  25 TSSNYLVQLPFTIFGFHTTWGAFSFPFIFLATDLTVRIFGAPLARRIIFAVMLPALLISYVISVLFY---QGSWQGFAAL 101
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446204314 119 HAIFDVVPRIALGSIVAYIIGQHIDVFIFSLIKKVfssdKTFFIRAYGSTFLSSIIDTAIFVAIAF 184
Cdd:PRK11212 102 AEFNLFVARIALASFMAYVLGQILDVHVFNRLRQS----RAWWVAPTASTLFGNLSDTLAFFFIAF 163
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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