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Conserved domains on  [gi|446133690|ref|WP_000211545|]
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MULTISPECIES: DUF2309 domain-containing protein [Staphylococcus]

Protein Classification

DUF2309 domain-containing protein( domain architecture ID 10562231)

DUF2309 domain-containing protein

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
DabA pfam10070
Probable inorganic carbon transporter subunit DabA; This entry represents the probable ...
14-885 0e+00

Probable inorganic carbon transporter subunit DabA; This entry represents the probable inorganic carbon transporter subunit DabA, which is part of an energy-coupled inorganic carbon pump together with DabB subunit in DAB operons (DAB1 and DAB2), found in a wide range of bacteria and archaea. Members of this family were previously known as UPF0753. DAB operon is required for CO2 concentrating mechanisms. The substrate of this subunit may be CO2 rather than carbonate ions based on kinetic calculations and in experimental assays in which E.coli was deleted of its carbonic anhydrase genes and expression of DAB2 operon restores its growth. Structural homology modelling suggests that DabA contains a domain that is distantly homologous to a type II beta-carbonic anhydrase (CA).


:

Pssm-ID: 431030  Cd Length: 759  Bit Score: 900.40  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133690   14 AKRVITPLSPISIFAARNPWEGLEADTFEDVAKWLRDVRDVDIFPNKALIESAVARGELDESVfnqlvtdmllehhynip 93
Cdd:pfam10070   2 AAHAIPPQWPLDSFVAVNPLHGLEDLPFEEAAARLARLFGARGYLPRAYYREALARGRIDPAD----------------- 64
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133690   94 qhyinlyidniktlkdvpasymnhsnvdvvadllLEKSKRDMAESYHHYDVRPMSDAIIDEQGEPLSEQVNRQMIKWTKL 173
Cdd:pfam10070  65 ----------------------------------LEAAAGSLALEAALGRLPTLADLLDALTGEDWDDLVDPQLIRWCAA 110
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133690  174 YIDQFLSSWTMPKREQSFYHAWLHLAQHDHSFT----KAQRQVIKGLPNDPEMTIESVLTYFSIDQEDYQAYVEGHLLAL 249
Cdd:pfam10070 111 FLDEGQAAWPMPGREQGLYAAWRELARHDRGPPlmglAGLRRRLAALPEDPEEAIAWALERLGIPEAAWEDYLEALLLAL 190
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133690  250 PGWAGMLYYRSQQHH----FEQHLLTDYLAIRLVVEQLLVGDEFKSVTKDCESRSENWFKQTVAslcyysdmpsdvllqh 325
Cdd:pfam10070 191 PGWAGMIRYREWQPAelqgAYPASLVDLLAIRLALEAALLAAVLRRNWGPPGSLPALEAAFEAA---------------- 254
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133690  326 dvneiqtfihFAATMNKNVFKNLWLIAWEMTYESQLKQKIKAGHESVAGAldvnqvnvsendnaNQPhsvllndtqavde 405
Cdd:pfam10070 255 ----------AADEFASAERGRLWLEAWERSYQRQLLAALAANSRAAAAA--------------TRP------------- 297
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133690  406 nnselnqvgtstKAQIAFCIDVRSEPFRRHIEAAGP-FETIGIAGFFGLPIQKDAVDEQFKHDSLPVMVPPAYRIKEFAD 484
Cdd:pfam10070 298 ------------AAQAVFCIDVRSESFRRHLEAVGPgYETFGFAGFFGVPIAYQGLGDDHARPLCPVLLTPAHRVREEPR 365
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133690  485 RYD-MNVYRQQQQTMSSMFYTFKLMKNNVMPSLLLPELSGPFLSLSTIVNSIMPRKSRASLQKIKQKWLKKPETKLTIDR 563
Cdd:pfam10070 366 DAAeAARARRRRRLRAAARRAWKRLKRSALSSFSFVEALGLLYGLKLLGRTLAPRRAARLPDRLGLRVLPKPATRLTLDR 445
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133690  564 EFDRtsdlpvGFTEQEQIDFALQALKLMDLTEAFAPFVVLAGHASHSHNNPHHASLECGACGGASSGFNAKLLAMICNRP 643
Cdd:pfam10070 446 LSDE------GFTLEEQVELAEGALRAMGLTRNFAPLVVLVGHGSTSVNNPHASALDCGACGGQSGGPNARVLAALLNDP 519
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133690  644 NVRQGLKQSGVYIPETTVFAAAEHHTSTDTLAWVYVpDTLSALALDAYESLNDAMPMISEQANRERLDKLPTIGRVNHPV 723
Cdd:pfam10070 520 EVRAGLAERGIDIPEDTVFVAALHNTTTDEVTLFDL-DLLPASHRADLERLRADLAEAGRLAAAERARRLPSAPRDAAAL 598
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133690  724 EEAQRFASDWSEVRPEWGLAKNASFIIGRRQLTKGIDLEGRTFLHNYDWRKDKDGKLLNTIISGPALVAQWINLQYYAST 803
Cdd:pfam10070 599 AHVRRRARDWSEVRPEWGLAGNAAFIIGPRSLTRGLDLDGRAFLHSYDWRQDPDGAVLELILTAPMVVAQWINLQYYFST 678
                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133690  804 VAPHFYGSGNKATQTVTSGVGVMQGNASDLMYGLSWQSVMAADRtMYHSPIRLLVVIQAPDYVVARLFANNEHFARKVSN 883
Cdd:pfam10070 679 VDNEVYGSGSKVLHNVVGLIGVMEGNGGDLRTGLPWQSVHDGDR-EYHEPLRLLVVIEAPREAIERILARHPAVRELVDN 757

                  ..
gi 446133690  884 HW 885
Cdd:pfam10070 758 GW 759
 
Name Accession Description Interval E-value
DabA pfam10070
Probable inorganic carbon transporter subunit DabA; This entry represents the probable ...
14-885 0e+00

Probable inorganic carbon transporter subunit DabA; This entry represents the probable inorganic carbon transporter subunit DabA, which is part of an energy-coupled inorganic carbon pump together with DabB subunit in DAB operons (DAB1 and DAB2), found in a wide range of bacteria and archaea. Members of this family were previously known as UPF0753. DAB operon is required for CO2 concentrating mechanisms. The substrate of this subunit may be CO2 rather than carbonate ions based on kinetic calculations and in experimental assays in which E.coli was deleted of its carbonic anhydrase genes and expression of DAB2 operon restores its growth. Structural homology modelling suggests that DabA contains a domain that is distantly homologous to a type II beta-carbonic anhydrase (CA).


Pssm-ID: 431030  Cd Length: 759  Bit Score: 900.40  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133690   14 AKRVITPLSPISIFAARNPWEGLEADTFEDVAKWLRDVRDVDIFPNKALIESAVARGELDESVfnqlvtdmllehhynip 93
Cdd:pfam10070   2 AAHAIPPQWPLDSFVAVNPLHGLEDLPFEEAAARLARLFGARGYLPRAYYREALARGRIDPAD----------------- 64
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133690   94 qhyinlyidniktlkdvpasymnhsnvdvvadllLEKSKRDMAESYHHYDVRPMSDAIIDEQGEPLSEQVNRQMIKWTKL 173
Cdd:pfam10070  65 ----------------------------------LEAAAGSLALEAALGRLPTLADLLDALTGEDWDDLVDPQLIRWCAA 110
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133690  174 YIDQFLSSWTMPKREQSFYHAWLHLAQHDHSFT----KAQRQVIKGLPNDPEMTIESVLTYFSIDQEDYQAYVEGHLLAL 249
Cdd:pfam10070 111 FLDEGQAAWPMPGREQGLYAAWRELARHDRGPPlmglAGLRRRLAALPEDPEEAIAWALERLGIPEAAWEDYLEALLLAL 190
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133690  250 PGWAGMLYYRSQQHH----FEQHLLTDYLAIRLVVEQLLVGDEFKSVTKDCESRSENWFKQTVAslcyysdmpsdvllqh 325
Cdd:pfam10070 191 PGWAGMIRYREWQPAelqgAYPASLVDLLAIRLALEAALLAAVLRRNWGPPGSLPALEAAFEAA---------------- 254
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133690  326 dvneiqtfihFAATMNKNVFKNLWLIAWEMTYESQLKQKIKAGHESVAGAldvnqvnvsendnaNQPhsvllndtqavde 405
Cdd:pfam10070 255 ----------AADEFASAERGRLWLEAWERSYQRQLLAALAANSRAAAAA--------------TRP------------- 297
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133690  406 nnselnqvgtstKAQIAFCIDVRSEPFRRHIEAAGP-FETIGIAGFFGLPIQKDAVDEQFKHDSLPVMVPPAYRIKEFAD 484
Cdd:pfam10070 298 ------------AAQAVFCIDVRSESFRRHLEAVGPgYETFGFAGFFGVPIAYQGLGDDHARPLCPVLLTPAHRVREEPR 365
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133690  485 RYD-MNVYRQQQQTMSSMFYTFKLMKNNVMPSLLLPELSGPFLSLSTIVNSIMPRKSRASLQKIKQKWLKKPETKLTIDR 563
Cdd:pfam10070 366 DAAeAARARRRRRLRAAARRAWKRLKRSALSSFSFVEALGLLYGLKLLGRTLAPRRAARLPDRLGLRVLPKPATRLTLDR 445
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133690  564 EFDRtsdlpvGFTEQEQIDFALQALKLMDLTEAFAPFVVLAGHASHSHNNPHHASLECGACGGASSGFNAKLLAMICNRP 643
Cdd:pfam10070 446 LSDE------GFTLEEQVELAEGALRAMGLTRNFAPLVVLVGHGSTSVNNPHASALDCGACGGQSGGPNARVLAALLNDP 519
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133690  644 NVRQGLKQSGVYIPETTVFAAAEHHTSTDTLAWVYVpDTLSALALDAYESLNDAMPMISEQANRERLDKLPTIGRVNHPV 723
Cdd:pfam10070 520 EVRAGLAERGIDIPEDTVFVAALHNTTTDEVTLFDL-DLLPASHRADLERLRADLAEAGRLAAAERARRLPSAPRDAAAL 598
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133690  724 EEAQRFASDWSEVRPEWGLAKNASFIIGRRQLTKGIDLEGRTFLHNYDWRKDKDGKLLNTIISGPALVAQWINLQYYAST 803
Cdd:pfam10070 599 AHVRRRARDWSEVRPEWGLAGNAAFIIGPRSLTRGLDLDGRAFLHSYDWRQDPDGAVLELILTAPMVVAQWINLQYYFST 678
                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133690  804 VAPHFYGSGNKATQTVTSGVGVMQGNASDLMYGLSWQSVMAADRtMYHSPIRLLVVIQAPDYVVARLFANNEHFARKVSN 883
Cdd:pfam10070 679 VDNEVYGSGSKVLHNVVGLIGVMEGNGGDLRTGLPWQSVHDGDR-EYHEPLRLLVVIEAPREAIERILARHPAVRELVDN 757

                  ..
gi 446133690  884 HW 885
Cdd:pfam10070 758 GW 759
MpsB COG3002
Na+-translocating membrane potential-generating system subunit MpsB, UPF0753/DUF2309 family ...
1-896 0e+00

Na+-translocating membrane potential-generating system subunit MpsB, UPF0753/DUF2309 family [Energy production and conversion];


Pssm-ID: 442240  Cd Length: 819  Bit Score: 603.79  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133690   1 MTTQLN----INSVIENAKRVITPLSPISIFAARNPWEGLEADTFEDVAKWLRDVRDVDIFPNKALIESAVARGELDESV 76
Cdd:COG3002    1 MNTLAGsefdLREALEEACHRIPPQWPLDDFVAVNPLHGLQDLPFAQAAARLARLFGARVTLPRAEYREAYASGRITDAD 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133690  77 FNQLVTDMLLEhhynipqhyinlyidniKTLKDvpasymnhsnvdvvadlLLEKSKRDMAESYHHydVRPMSDAIIDEQG 156
Cdd:COG3002   81 LEAALAEAGGA-----------------LSLEE-----------------LKAALLQPPPAPPPA--LPLLRDLLKRLTG 124
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133690 157 EPLSEQVNRQMIKWTKLYIDQFLSSWTMPKREQSFYHAWLHLAQHDHS----FTKAQRQVIKGLPNDPEMTIESVLTYFS 232
Cdd:COG3002  125 IDWDQLVHPQISRWCAAYFDQGQALWQPPGRGKGLYAAWRELATHDLTpllmGLRGLRARVAALPEDAEAAIAWALERLG 204
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133690 233 IDQEDYQAYVEGHLLALPGWAGMLYYRSQQHHF---EQHLLTDYLAIRLVVEQLLVGDEFKSVtkdcesrSENWfKQTVA 309
Cdd:COG3002  205 LPEAAWEDYLHALLLSLGGWAGWARYLEWQAELagrRDITLRDLLAIRLAWEAALLDEKRGAL-------EAAW-RAALA 276
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133690 310 SLCYYSDMPSDVLlqhDVNEIqtfihfaatmnknvfknlWLIAWEMTYESQLKQKIKAghesvagaldvnqvnvsendna 389
Cdd:COG3002  277 AQAAPAVEATEAL---EVDEI------------------WQEALERAYQRELLAGLAA---------------------- 313
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133690 390 nqphsvllndtqavdenNSELNQVGTSTKAQIAFCIDVRSEPFRRHIEAAGP-FETIGIAGFFGLPIQKDAVDEQFKHDS 468
Cdd:COG3002  314 -----------------APTPAPPAERPAVQAAFCIDVRSEVFRRALEAVDPgIETLGFAGFFGVPIAYRPLGSDAARPQ 376
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133690 469 LPVMVPPAYRIKEFADRYDMNVY-RQQQQTMSSMFYTFKLmknNVMPSLLLPELSGPFLSLSTIVNSIMPRKSRASLQKI 547
Cdd:COG3002  377 CPVLLAPKYLVKEVPLEAAAADRaRRRRLRAARAWKRFKR---SAVSGFSFVETLGLLYAGKLLGDSLGPSRPVALPDAF 453
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133690 548 KQKWLKKPETKLTIDREFDRtsDLPVGFTEQEQIDFALQALKLMDLTEAFAPFVVLAGHASHSHNNPHHASLECGACGGA 627
Cdd:COG3002  454 GLMAKERPRTRPRLENEDEN--GLQIGFTLDERAALAEGVLRAMGLTRGFAPLVLLVGHGSSSVNNPHAAALDCGACGGQ 531
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133690 628 SSGFNAKLLAMICNRPNVRQGLKQSGVYIPETTVFAAAEHHTSTDTLAWvYVPDTLSALALDAYESLNDAMPMISEQANR 707
Cdd:COG3002  532 TGEVNARVLAALLNDPEVRAGLAERGIDIPEDTVFVAALHDTTTDEITL-FDLDLLPASHRADLARLQRWLAQAGDLARR 610
                        730       740       750       760       770       780       790       800
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133690 708 ERLDKLPTIGRVNHPV--EEAQRFASDWSEVRPEWGLAKNASFIIGRRQLTKGIDLEGRTFLHNYDWRKDKDGKLLNTII 785
Cdd:COG3002  611 ERARRLGLAPTKSPEAllADVRRRARDWAEVRPEWGLAGNAAFIVAPRSRTRGLFLDGRAFLHSYDWRQDPDGAVLELIL 690
                        810       820       830       840       850       860       870       880
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133690 786 SGPALVAQWINLQYYASTVAPHFYGSGNKATQTVTSGVGVMQGNASDLMYGLSWQSVMAADRtMYHSPIRLLVVIQAPDY 865
Cdd:COG3002  691 TAPMVVAHWINLQYYFSTVDNERFGSGNKLLHNVVGLIGVFEGNGGDLRTGLPWQSVHDGER-WVHEPLRLLVVIEAPPE 769
                        890       900       910
                 ....*....|....*....|....*....|.
gi 446133690 866 VVARLFANNEHFARKVSNHWLRLMSVNEEGR 896
Cdd:COG3002  770 AIDAVIARHPAVRELVDNGWLHLFALDPEGR 800
 
Name Accession Description Interval E-value
DabA pfam10070
Probable inorganic carbon transporter subunit DabA; This entry represents the probable ...
14-885 0e+00

Probable inorganic carbon transporter subunit DabA; This entry represents the probable inorganic carbon transporter subunit DabA, which is part of an energy-coupled inorganic carbon pump together with DabB subunit in DAB operons (DAB1 and DAB2), found in a wide range of bacteria and archaea. Members of this family were previously known as UPF0753. DAB operon is required for CO2 concentrating mechanisms. The substrate of this subunit may be CO2 rather than carbonate ions based on kinetic calculations and in experimental assays in which E.coli was deleted of its carbonic anhydrase genes and expression of DAB2 operon restores its growth. Structural homology modelling suggests that DabA contains a domain that is distantly homologous to a type II beta-carbonic anhydrase (CA).


Pssm-ID: 431030  Cd Length: 759  Bit Score: 900.40  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133690   14 AKRVITPLSPISIFAARNPWEGLEADTFEDVAKWLRDVRDVDIFPNKALIESAVARGELDESVfnqlvtdmllehhynip 93
Cdd:pfam10070   2 AAHAIPPQWPLDSFVAVNPLHGLEDLPFEEAAARLARLFGARGYLPRAYYREALARGRIDPAD----------------- 64
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133690   94 qhyinlyidniktlkdvpasymnhsnvdvvadllLEKSKRDMAESYHHYDVRPMSDAIIDEQGEPLSEQVNRQMIKWTKL 173
Cdd:pfam10070  65 ----------------------------------LEAAAGSLALEAALGRLPTLADLLDALTGEDWDDLVDPQLIRWCAA 110
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133690  174 YIDQFLSSWTMPKREQSFYHAWLHLAQHDHSFT----KAQRQVIKGLPNDPEMTIESVLTYFSIDQEDYQAYVEGHLLAL 249
Cdd:pfam10070 111 FLDEGQAAWPMPGREQGLYAAWRELARHDRGPPlmglAGLRRRLAALPEDPEEAIAWALERLGIPEAAWEDYLEALLLAL 190
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133690  250 PGWAGMLYYRSQQHH----FEQHLLTDYLAIRLVVEQLLVGDEFKSVTKDCESRSENWFKQTVAslcyysdmpsdvllqh 325
Cdd:pfam10070 191 PGWAGMIRYREWQPAelqgAYPASLVDLLAIRLALEAALLAAVLRRNWGPPGSLPALEAAFEAA---------------- 254
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133690  326 dvneiqtfihFAATMNKNVFKNLWLIAWEMTYESQLKQKIKAGHESVAGAldvnqvnvsendnaNQPhsvllndtqavde 405
Cdd:pfam10070 255 ----------AADEFASAERGRLWLEAWERSYQRQLLAALAANSRAAAAA--------------TRP------------- 297
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133690  406 nnselnqvgtstKAQIAFCIDVRSEPFRRHIEAAGP-FETIGIAGFFGLPIQKDAVDEQFKHDSLPVMVPPAYRIKEFAD 484
Cdd:pfam10070 298 ------------AAQAVFCIDVRSESFRRHLEAVGPgYETFGFAGFFGVPIAYQGLGDDHARPLCPVLLTPAHRVREEPR 365
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133690  485 RYD-MNVYRQQQQTMSSMFYTFKLMKNNVMPSLLLPELSGPFLSLSTIVNSIMPRKSRASLQKIKQKWLKKPETKLTIDR 563
Cdd:pfam10070 366 DAAeAARARRRRRLRAAARRAWKRLKRSALSSFSFVEALGLLYGLKLLGRTLAPRRAARLPDRLGLRVLPKPATRLTLDR 445
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133690  564 EFDRtsdlpvGFTEQEQIDFALQALKLMDLTEAFAPFVVLAGHASHSHNNPHHASLECGACGGASSGFNAKLLAMICNRP 643
Cdd:pfam10070 446 LSDE------GFTLEEQVELAEGALRAMGLTRNFAPLVVLVGHGSTSVNNPHASALDCGACGGQSGGPNARVLAALLNDP 519
                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133690  644 NVRQGLKQSGVYIPETTVFAAAEHHTSTDTLAWVYVpDTLSALALDAYESLNDAMPMISEQANRERLDKLPTIGRVNHPV 723
Cdd:pfam10070 520 EVRAGLAERGIDIPEDTVFVAALHNTTTDEVTLFDL-DLLPASHRADLERLRADLAEAGRLAAAERARRLPSAPRDAAAL 598
                         730       740       750       760       770       780       790       800
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133690  724 EEAQRFASDWSEVRPEWGLAKNASFIIGRRQLTKGIDLEGRTFLHNYDWRKDKDGKLLNTIISGPALVAQWINLQYYAST 803
Cdd:pfam10070 599 AHVRRRARDWSEVRPEWGLAGNAAFIIGPRSLTRGLDLDGRAFLHSYDWRQDPDGAVLELILTAPMVVAQWINLQYYFST 678
                         810       820       830       840       850       860       870       880
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133690  804 VAPHFYGSGNKATQTVTSGVGVMQGNASDLMYGLSWQSVMAADRtMYHSPIRLLVVIQAPDYVVARLFANNEHFARKVSN 883
Cdd:pfam10070 679 VDNEVYGSGSKVLHNVVGLIGVMEGNGGDLRTGLPWQSVHDGDR-EYHEPLRLLVVIEAPREAIERILARHPAVRELVDN 757

                  ..
gi 446133690  884 HW 885
Cdd:pfam10070 758 GW 759
MpsB COG3002
Na+-translocating membrane potential-generating system subunit MpsB, UPF0753/DUF2309 family ...
1-896 0e+00

Na+-translocating membrane potential-generating system subunit MpsB, UPF0753/DUF2309 family [Energy production and conversion];


Pssm-ID: 442240  Cd Length: 819  Bit Score: 603.79  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133690   1 MTTQLN----INSVIENAKRVITPLSPISIFAARNPWEGLEADTFEDVAKWLRDVRDVDIFPNKALIESAVARGELDESV 76
Cdd:COG3002    1 MNTLAGsefdLREALEEACHRIPPQWPLDDFVAVNPLHGLQDLPFAQAAARLARLFGARVTLPRAEYREAYASGRITDAD 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133690  77 FNQLVTDMLLEhhynipqhyinlyidniKTLKDvpasymnhsnvdvvadlLLEKSKRDMAESYHHydVRPMSDAIIDEQG 156
Cdd:COG3002   81 LEAALAEAGGA-----------------LSLEE-----------------LKAALLQPPPAPPPA--LPLLRDLLKRLTG 124
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133690 157 EPLSEQVNRQMIKWTKLYIDQFLSSWTMPKREQSFYHAWLHLAQHDHS----FTKAQRQVIKGLPNDPEMTIESVLTYFS 232
Cdd:COG3002  125 IDWDQLVHPQISRWCAAYFDQGQALWQPPGRGKGLYAAWRELATHDLTpllmGLRGLRARVAALPEDAEAAIAWALERLG 204
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133690 233 IDQEDYQAYVEGHLLALPGWAGMLYYRSQQHHF---EQHLLTDYLAIRLVVEQLLVGDEFKSVtkdcesrSENWfKQTVA 309
Cdd:COG3002  205 LPEAAWEDYLHALLLSLGGWAGWARYLEWQAELagrRDITLRDLLAIRLAWEAALLDEKRGAL-------EAAW-RAALA 276
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133690 310 SLCYYSDMPSDVLlqhDVNEIqtfihfaatmnknvfknlWLIAWEMTYESQLKQKIKAghesvagaldvnqvnvsendna 389
Cdd:COG3002  277 AQAAPAVEATEAL---EVDEI------------------WQEALERAYQRELLAGLAA---------------------- 313
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133690 390 nqphsvllndtqavdenNSELNQVGTSTKAQIAFCIDVRSEPFRRHIEAAGP-FETIGIAGFFGLPIQKDAVDEQFKHDS 468
Cdd:COG3002  314 -----------------APTPAPPAERPAVQAAFCIDVRSEVFRRALEAVDPgIETLGFAGFFGVPIAYRPLGSDAARPQ 376
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133690 469 LPVMVPPAYRIKEFADRYDMNVY-RQQQQTMSSMFYTFKLmknNVMPSLLLPELSGPFLSLSTIVNSIMPRKSRASLQKI 547
Cdd:COG3002  377 CPVLLAPKYLVKEVPLEAAAADRaRRRRLRAARAWKRFKR---SAVSGFSFVETLGLLYAGKLLGDSLGPSRPVALPDAF 453
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133690 548 KQKWLKKPETKLTIDREFDRtsDLPVGFTEQEQIDFALQALKLMDLTEAFAPFVVLAGHASHSHNNPHHASLECGACGGA 627
Cdd:COG3002  454 GLMAKERPRTRPRLENEDEN--GLQIGFTLDERAALAEGVLRAMGLTRGFAPLVLLVGHGSSSVNNPHAAALDCGACGGQ 531
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133690 628 SSGFNAKLLAMICNRPNVRQGLKQSGVYIPETTVFAAAEHHTSTDTLAWvYVPDTLSALALDAYESLNDAMPMISEQANR 707
Cdd:COG3002  532 TGEVNARVLAALLNDPEVRAGLAERGIDIPEDTVFVAALHDTTTDEITL-FDLDLLPASHRADLARLQRWLAQAGDLARR 610
                        730       740       750       760       770       780       790       800
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133690 708 ERLDKLPTIGRVNHPV--EEAQRFASDWSEVRPEWGLAKNASFIIGRRQLTKGIDLEGRTFLHNYDWRKDKDGKLLNTII 785
Cdd:COG3002  611 ERARRLGLAPTKSPEAllADVRRRARDWAEVRPEWGLAGNAAFIVAPRSRTRGLFLDGRAFLHSYDWRQDPDGAVLELIL 690
                        810       820       830       840       850       860       870       880
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446133690 786 SGPALVAQWINLQYYASTVAPHFYGSGNKATQTVTSGVGVMQGNASDLMYGLSWQSVMAADRtMYHSPIRLLVVIQAPDY 865
Cdd:COG3002  691 TAPMVVAHWINLQYYFSTVDNERFGSGNKLLHNVVGLIGVFEGNGGDLRTGLPWQSVHDGER-WVHEPLRLLVVIEAPPE 769
                        890       900       910
                 ....*....|....*....|....*....|.
gi 446133690 866 VVARLFANNEHFARKVSNHWLRLMSVNEEGR 896
Cdd:COG3002  770 AIDAVIARHPAVRELVDNGWLHLFALDPEGR 800
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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