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Conserved domains on  [gi|446063778|ref|WP_000141633|]
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MULTISPECIES: type I toxin-antitoxin system toxin Ldr family protein [Enterobacteriaceae]

Protein Classification

type I toxin-antitoxin system toxin Ldr family protein( domain architecture ID 10622324)

type I toxin-antitoxin system toxin Ldr (long direct repeat) family protein inhibits cell growth, decreases cell viability and causes nucleoid condensation

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Ldr_toxin pfam13940
Toxin Ldr, type I toxin-antitoxin system; This family includes the Ldr (long direct repeat) ...
 1-35 1.91e-13

Toxin Ldr, type I toxin-antitoxin system; This family includes the Ldr (long direct repeat) toxins. In Escherichia coli there are four Ldr toxins, LdrA, LdrB, LdrC and LdrD. These toxins inhibit cell growth, decrease cell viability and cause nucleoid condensation. LdrD expression is inhibited by the antisense RNA RdlD, which functions as an antitoxin.


:

Pssm-ID: 404772  Cd Length: 35  Bit Score: 56.16  E-value: 1.91e-13
                         10        20        30
                 ....*....|....*....|....*....|....*
gi 446063778   1 MTFAELGMAFLHDLAAPVIAGILASMIVNWLNKRK 35
Cdd:pfam13940  1 MTFAEFAMAFWHDLAAPIIAGIIAAAIVGWLNKRK 35
 
Name Accession Description Interval E-value
Ldr_toxin pfam13940
Toxin Ldr, type I toxin-antitoxin system; This family includes the Ldr (long direct repeat) ...
 1-35 1.91e-13

Toxin Ldr, type I toxin-antitoxin system; This family includes the Ldr (long direct repeat) toxins. In Escherichia coli there are four Ldr toxins, LdrA, LdrB, LdrC and LdrD. These toxins inhibit cell growth, decrease cell viability and cause nucleoid condensation. LdrD expression is inhibited by the antisense RNA RdlD, which functions as an antitoxin.


Pssm-ID: 404772  Cd Length: 35  Bit Score: 56.16  E-value: 1.91e-13
                         10        20        30
                 ....*....|....*....|....*....|....*
gi 446063778   1 MTFAELGMAFLHDLAAPVIAGILASMIVNWLNKRK 35
Cdd:pfam13940  1 MTFAEFAMAFWHDLAAPIIAGIIAAAIVGWLNKRK 35
 
Name Accession Description Interval E-value
Ldr_toxin pfam13940
Toxin Ldr, type I toxin-antitoxin system; This family includes the Ldr (long direct repeat) ...
 1-35 1.91e-13

Toxin Ldr, type I toxin-antitoxin system; This family includes the Ldr (long direct repeat) toxins. In Escherichia coli there are four Ldr toxins, LdrA, LdrB, LdrC and LdrD. These toxins inhibit cell growth, decrease cell viability and cause nucleoid condensation. LdrD expression is inhibited by the antisense RNA RdlD, which functions as an antitoxin.


Pssm-ID: 404772  Cd Length: 35  Bit Score: 56.16  E-value: 1.91e-13
                         10        20        30
                 ....*....|....*....|....*....|....*
gi 446063778   1 MTFAELGMAFLHDLAAPVIAGILASMIVNWLNKRK 35
Cdd:pfam13940  1 MTFAEFAMAFWHDLAAPIIAGIIAAAIVGWLNKRK 35
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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