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Conserved domains on  [gi|446057777|ref|WP_000135632|]
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MULTISPECIES: F0F1 ATP synthase subunit A [Salmonella]

Protein Classification

FoF1 ATP synthase subunit a( domain architecture ID 10012597)

FoF1 ATP synthase subunit a is part of the membrane proton channel of the F-type ATPase that produces ATP from ADP in the presence of a proton gradient across the membrane; it plays a direct role in the translocation of protons across the membrane

Gene Ontology:  GO:0045263|GO:0046933|GO:0005886
PubMed:  28001127

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK05815 PRK05815
F0F1 ATP synthase subunit A; Validated
 38-271 3.33e-78

F0F1 ATP synthase subunit A; Validated


:

Pssm-ID: 235617  Cd Length: 227  Bit Score: 236.23  E-value: 3.33e-78
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446057777  38 FWTLNIDSMFFSVVLGLLFLVMFRSVAKKATSGVPGKFQTAIELIVGFVHGSVKDMYHGKSKLIAPLALTIFVWVFLMNL 117
Cdd:PRK05815   9 FGGFNFDSLLLSVLLGVLILLLFALVATRKLSGVPGGLQNFVEMIVEFVRGQVKDNIGGKGKKFAPLAFTLFLFILLMNL 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446057777 118 MDLLPIdllpyiaehwlglpaTRVVPSADVNITLSMALGVFILILFYSIKMKGIGGFAKELTLQPFnhWAFIPVNLIleg 197
Cdd:PRK05815  89 LGLIPY---------------LLFPPTADINVTLALALIVFVLVIYYGIKKKGLGGYLKEFYLQPH--PLLLPIEII--- 148

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446057777 198 vSLLSKPVSLGLRLFGNMYAGELIFILI-----AGLLPWWSQWILNVPWAIFHILIITLQAFIFMVLTIVYLSMASEEH 271
Cdd:PRK05815 149 -SEFSRPISLSLRLFGNMLAGELILALIallggAGLLLALAPLILPVAWTIFEIFVGTLQAYIFMMLTIVYISMAVEEE 226
 
Name Accession Description Interval E-value
PRK05815 PRK05815
F0F1 ATP synthase subunit A; Validated
 38-271 3.33e-78

F0F1 ATP synthase subunit A; Validated


Pssm-ID: 235617  Cd Length: 227  Bit Score: 236.23  E-value: 3.33e-78
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446057777  38 FWTLNIDSMFFSVVLGLLFLVMFRSVAKKATSGVPGKFQTAIELIVGFVHGSVKDMYHGKSKLIAPLALTIFVWVFLMNL 117
Cdd:PRK05815   9 FGGFNFDSLLLSVLLGVLILLLFALVATRKLSGVPGGLQNFVEMIVEFVRGQVKDNIGGKGKKFAPLAFTLFLFILLMNL 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446057777 118 MDLLPIdllpyiaehwlglpaTRVVPSADVNITLSMALGVFILILFYSIKMKGIGGFAKELTLQPFnhWAFIPVNLIleg 197
Cdd:PRK05815  89 LGLIPY---------------LLFPPTADINVTLALALIVFVLVIYYGIKKKGLGGYLKEFYLQPH--PLLLPIEII--- 148

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446057777 198 vSLLSKPVSLGLRLFGNMYAGELIFILI-----AGLLPWWSQWILNVPWAIFHILIITLQAFIFMVLTIVYLSMASEEH 271
Cdd:PRK05815 149 -SEFSRPISLSLRLFGNMLAGELILALIallggAGLLLALAPLILPVAWTIFEIFVGTLQAYIFMMLTIVYISMAVEEE 226
AtpB COG0356
FoF1-type ATP synthase, membrane subunit a [Energy production and conversion]; FoF1-type ATP ...
 44-270 7.71e-73

FoF1-type ATP synthase, membrane subunit a [Energy production and conversion]; FoF1-type ATP synthase, membrane subunit a is part of the Pathway/BioSystem: FoF1-type ATP synthase


Pssm-ID: 440125 [Multi-domain]  Cd Length: 212  Bit Score: 221.87  E-value: 7.71e-73
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446057777  44 DSMFFSVVLGLLFLVMFRSVAKKAtSGVPGKFQTAIELIVGFVHGSVKDMYHGKSKLIAPLALTIFVWVFLMNLMDLLPi 123
Cdd:COG0356    1 DTVLMSWLAMLLLLLLFLLATRKL-KLVPGGLQNFVEMLVEFVRNQVKDTIGKKGRKFAPLLLTLFLFILVSNLLGLIP- 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446057777 124 dllpyiaehwlGLpatrVVPSADVNITLSMALGVFILILFYSIKMKGIGGFAKELTLQPFnhWAFIPVNLILEGVSLLSK 203
Cdd:COG0356   79 -----------GL----FPPTADINVTLALALIVFVLVHYYGIKKKGLGGYLKHLFFPPF--PWLAPLMLPIEIISELAR 141

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446057777 204 PVSLGLRLFGNMYAGELIFILIAGLLPWWS----QWILNVPWAIFHILIITLQAFIFMVLTIVYLSMASEE 270
Cdd:COG0356  142 PLSLSLRLFGNMFAGHIILLLLAGLAPFLLlgvlSLLLPVAWTAFELLVGFLQAYIFTMLTAVYISLAVEE 212
ATP-synt_A pfam00119
ATP synthase A chain;
46-265 7.98e-59

ATP synthase A chain;


Pssm-ID: 459679 [Multi-domain]  Cd Length: 216  Bit Score: 186.16  E-value: 7.98e-59
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446057777   46 MFFSVVLGLLFLVMFRSVAKKATSGVPGKFQTAIELIVGFVHGSVKDMYHGKS-KLIAPLALTIFVWVFLMNLMDLLPId 124
Cdd:pfam00119   1 LLMSLIVALILLLFLLLATRKTKKLVPGRLQNFVEMLVEFVDNIVKDNIGKKKgRKFFPLLLTLFFFILVSNLLGLIPK- 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446057777  125 lLPYIAEhwlglpatrvvPSADVNITLSMALGVFILILFYSIKMKGIGGFAKELTLqPFNHWAFIPVNLILEGVSLLSKP 204
Cdd:pfam00119  80 -SPGGFT-----------VTADINVTLALALIVFLLVHYYGIKKHGLGGYFKKLFV-PPVPLPLVPLLLPIEIISEFARP 146

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446057777  205 VSLGLRLFGNMYAGELIFILIAGLLPW---------WSQWILNVPWAIFHILIITLQAFIFMVLTIVYLS 265
Cdd:pfam00119 147 VSLSLRLFGNMLAGHLLLLLLAGLIFAllsagfllgVIPPLLGVAWTLFELLVAFIQAYVFTMLTAVYIS 216
ATP_synt_6_or_A TIGR01131
ATP synthase subunit 6 (eukaryotes),also subunit A (prokaryotes); Bacterial forms should be ...
 35-265 1.23e-32

ATP synthase subunit 6 (eukaryotes),also subunit A (prokaryotes); Bacterial forms should be designated ATP synthase, F0 subunit A; eukaryotic (chloroplast and mitochondrial) forms should be designated ATP synthase, F0 subunit 6. The F1/F0 ATP synthase is a multisubunit, membrane associated enzyme found in bacteria and mitochondria and chloroplast. This enzyme is principally involved in the synthesis of ATP from ADP and inorganic phosphate by coupling the energy derived from the proton electrochemical gradient across the biological membrane. A brief description of this multisubunit enzyme complex: F1 and F0 represent two major clusters of subunits. Individual subunits in each of these clusters are named differently in prokaryotes and in organelles e.g., mitochondria and chloroplast. The bacterial equivalent of subunit 6 is named subunit 'A'. It has been shown that proton is conducted though this subunit. Typically, deprotonation and reprotonation of the acidic amino acid side-chains are implicated in the process. [Energy metabolism, ATP-proton motive force interconversion]


Pssm-ID: 273458  Cd Length: 226  Bit Score: 119.23  E-value: 1.23e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446057777   35 PATFWTLNIDSMFFSVVLGLLFLVMFRSVAKKAtsgVPGKFQTAIELIVGFVHGSVKDMYHGKSKLIAPLALTIFVWVFL 114
Cdd:TIGR01131   7 ISPITLFSLTLLSLILLLSLLIFLISSSLSRWL---IPSRWQNLMESIYEFVLSIVKSQIGGKKGKFFPLIFTLFLFILI 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446057777  115 MNLMDLLPidllpyiaehwlglpaTRVVPSADVNITLSMALGVFILILFYSIKMKGIGGFAkELTLQPFNHWaFIPVNLI 194
Cdd:TIGR01131  84 SNLLGLIP----------------YSFTPTSHLSFTLGLALPLWLGLTISGFRKHPKGFLA-HLVPSGTPLP-LIPFLVI 145

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446057777  195 LEGVSLLSKPVSLGLRLFGNMYAGELIFILIAGLLPWWSQ-------WILNVPWAIFHILIITLQAFIFMVLTIVYLS 265
Cdd:TIGR01131 146 IETISYLARPISLSVRLFANISAGHLLLTLLSGLLFSLMSsaifallLLILVALIILEIFVAFIQAYVFTLLTCLYLN 223
ATP-synt_Fo_a_6 cd00310
ATP synthase Fo complex, subunit 6 (eukaryotes) and subunit a (prokaryotes); Bacterial forms ...
 99-265 6.80e-29

ATP synthase Fo complex, subunit 6 (eukaryotes) and subunit a (prokaryotes); Bacterial forms are designated as ATP synthase, Fo complex, subunit a; eukaryotic (chloroplast and mitochondrial) forms are designated as ATP synthase, Fo complex, subunit 6. The F-ATP synthases (also called FoF1-ATPases) consist of two structural domains: F1 (factor one) complex containing the soluble catalytic core, and Fo (oligomycin sensitive factor) complex containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. F-ATP synthases are primarily found in the inner membranes of eukaryotic mitochondria, in the thylakoid membranes of chloroplasts or in the plasma membranes of bacteria. F-ATP synthase has also been found in the archaea Methanosarcina acetivorans. F-ATP synthases are the primary producers of ATP, using the proton gradient generated by oxidative phosphorylation (mitochondria) or photosynthesis (chloroplasts). Alternatively, under conditions of low driving force, ATP synthases function as ATPases, thus generating a transmembrane proton or Na(+) gradient at the expense of energy derived from ATP hydrolysis.


Pssm-ID: 349411 [Multi-domain]  Cd Length: 156  Bit Score: 107.49  E-value: 6.80e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446057777  99 KLIAPLALTIFVWVFLMNLMDLLPIdllpyiaehwlglpatRVVPSADVNITLSMALGVFILILFYSIKMKGIGGFAKEL 178
Cdd:cd00310    2 KKYLPLLGTLFLFILFSNLLGLIPY----------------SFTPTSHLNVTLALALIVFLGVHILGIKKHGLGFFLHFL 65

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446057777 179 TLQPFnhWAFIPVNLILEGVSLLSKPVSLGLRLFGNMYAGELIFILIAGLLPWWSQW------ILNVPWAIFHILIITLQ 252
Cdd:cd00310   66 PPGTP--LPLAPLMVPIELISELIRPLSLSVRLFANMFAGHLLLALLSGLVPSLLSSvgllplLLPVALTLLELFVAFIQ 143

                        170
                 ....*....|...
gi 446057777 253 AFIFMVLTIVYLS 265
Cdd:cd00310  144 AYVFTLLTAVYIS 156
 
Name Accession Description Interval E-value
PRK05815 PRK05815
F0F1 ATP synthase subunit A; Validated
 38-271 3.33e-78

F0F1 ATP synthase subunit A; Validated


Pssm-ID: 235617  Cd Length: 227  Bit Score: 236.23  E-value: 3.33e-78
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446057777  38 FWTLNIDSMFFSVVLGLLFLVMFRSVAKKATSGVPGKFQTAIELIVGFVHGSVKDMYHGKSKLIAPLALTIFVWVFLMNL 117
Cdd:PRK05815   9 FGGFNFDSLLLSVLLGVLILLLFALVATRKLSGVPGGLQNFVEMIVEFVRGQVKDNIGGKGKKFAPLAFTLFLFILLMNL 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446057777 118 MDLLPIdllpyiaehwlglpaTRVVPSADVNITLSMALGVFILILFYSIKMKGIGGFAKELTLQPFnhWAFIPVNLIleg 197
Cdd:PRK05815  89 LGLIPY---------------LLFPPTADINVTLALALIVFVLVIYYGIKKKGLGGYLKEFYLQPH--PLLLPIEII--- 148

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 446057777 198 vSLLSKPVSLGLRLFGNMYAGELIFILI-----AGLLPWWSQWILNVPWAIFHILIITLQAFIFMVLTIVYLSMASEEH 271
Cdd:PRK05815 149 -SEFSRPISLSLRLFGNMLAGELILALIallggAGLLLALAPLILPVAWTIFEIFVGTLQAYIFMMLTIVYISMAVEEE 226
AtpB COG0356
FoF1-type ATP synthase, membrane subunit a [Energy production and conversion]; FoF1-type ATP ...
 44-270 7.71e-73

FoF1-type ATP synthase, membrane subunit a [Energy production and conversion]; FoF1-type ATP synthase, membrane subunit a is part of the Pathway/BioSystem: FoF1-type ATP synthase


Pssm-ID: 440125 [Multi-domain]  Cd Length: 212  Bit Score: 221.87  E-value: 7.71e-73
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446057777  44 DSMFFSVVLGLLFLVMFRSVAKKAtSGVPGKFQTAIELIVGFVHGSVKDMYHGKSKLIAPLALTIFVWVFLMNLMDLLPi 123
Cdd:COG0356    1 DTVLMSWLAMLLLLLLFLLATRKL-KLVPGGLQNFVEMLVEFVRNQVKDTIGKKGRKFAPLLLTLFLFILVSNLLGLIP- 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446057777 124 dllpyiaehwlGLpatrVVPSADVNITLSMALGVFILILFYSIKMKGIGGFAKELTLQPFnhWAFIPVNLILEGVSLLSK 203
Cdd:COG0356   79 -----------GL----FPPTADINVTLALALIVFVLVHYYGIKKKGLGGYLKHLFFPPF--PWLAPLMLPIEIISELAR 141

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 446057777 204 PVSLGLRLFGNMYAGELIFILIAGLLPWWS----QWILNVPWAIFHILIITLQAFIFMVLTIVYLSMASEE 270
Cdd:COG0356  142 PLSLSLRLFGNMFAGHIILLLLAGLAPFLLlgvlSLLLPVAWTAFELLVGFLQAYIFTMLTAVYISLAVEE 212
ATP-synt_A pfam00119
ATP synthase A chain;
46-265 7.98e-59

ATP synthase A chain;


Pssm-ID: 459679 [Multi-domain]  Cd Length: 216  Bit Score: 186.16  E-value: 7.98e-59
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446057777   46 MFFSVVLGLLFLVMFRSVAKKATSGVPGKFQTAIELIVGFVHGSVKDMYHGKS-KLIAPLALTIFVWVFLMNLMDLLPId 124
Cdd:pfam00119   1 LLMSLIVALILLLFLLLATRKTKKLVPGRLQNFVEMLVEFVDNIVKDNIGKKKgRKFFPLLLTLFFFILVSNLLGLIPK- 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446057777  125 lLPYIAEhwlglpatrvvPSADVNITLSMALGVFILILFYSIKMKGIGGFAKELTLqPFNHWAFIPVNLILEGVSLLSKP 204
Cdd:pfam00119  80 -SPGGFT-----------VTADINVTLALALIVFLLVHYYGIKKHGLGGYFKKLFV-PPVPLPLVPLLLPIEIISEFARP 146

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446057777  205 VSLGLRLFGNMYAGELIFILIAGLLPW---------WSQWILNVPWAIFHILIITLQAFIFMVLTIVYLS 265
Cdd:pfam00119 147 VSLSLRLFGNMLAGHLLLLLLAGLIFAllsagfllgVIPPLLGVAWTLFELLVAFIQAYVFTMLTAVYIS 216
ATP_synt_6_or_A TIGR01131
ATP synthase subunit 6 (eukaryotes),also subunit A (prokaryotes); Bacterial forms should be ...
 35-265 1.23e-32

ATP synthase subunit 6 (eukaryotes),also subunit A (prokaryotes); Bacterial forms should be designated ATP synthase, F0 subunit A; eukaryotic (chloroplast and mitochondrial) forms should be designated ATP synthase, F0 subunit 6. The F1/F0 ATP synthase is a multisubunit, membrane associated enzyme found in bacteria and mitochondria and chloroplast. This enzyme is principally involved in the synthesis of ATP from ADP and inorganic phosphate by coupling the energy derived from the proton electrochemical gradient across the biological membrane. A brief description of this multisubunit enzyme complex: F1 and F0 represent two major clusters of subunits. Individual subunits in each of these clusters are named differently in prokaryotes and in organelles e.g., mitochondria and chloroplast. The bacterial equivalent of subunit 6 is named subunit 'A'. It has been shown that proton is conducted though this subunit. Typically, deprotonation and reprotonation of the acidic amino acid side-chains are implicated in the process. [Energy metabolism, ATP-proton motive force interconversion]


Pssm-ID: 273458  Cd Length: 226  Bit Score: 119.23  E-value: 1.23e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446057777   35 PATFWTLNIDSMFFSVVLGLLFLVMFRSVAKKAtsgVPGKFQTAIELIVGFVHGSVKDMYHGKSKLIAPLALTIFVWVFL 114
Cdd:TIGR01131   7 ISPITLFSLTLLSLILLLSLLIFLISSSLSRWL---IPSRWQNLMESIYEFVLSIVKSQIGGKKGKFFPLIFTLFLFILI 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446057777  115 MNLMDLLPidllpyiaehwlglpaTRVVPSADVNITLSMALGVFILILFYSIKMKGIGGFAkELTLQPFNHWaFIPVNLI 194
Cdd:TIGR01131  84 SNLLGLIP----------------YSFTPTSHLSFTLGLALPLWLGLTISGFRKHPKGFLA-HLVPSGTPLP-LIPFLVI 145

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446057777  195 LEGVSLLSKPVSLGLRLFGNMYAGELIFILIAGLLPWWSQ-------WILNVPWAIFHILIITLQAFIFMVLTIVYLS 265
Cdd:TIGR01131 146 IETISYLARPISLSVRLFANISAGHLLLTLLSGLLFSLMSsaifallLLILVALIILEIFVAFIQAYVFTLLTCLYLN 223
ATP-synt_Fo_a_6 cd00310
ATP synthase Fo complex, subunit 6 (eukaryotes) and subunit a (prokaryotes); Bacterial forms ...
 99-265 6.80e-29

ATP synthase Fo complex, subunit 6 (eukaryotes) and subunit a (prokaryotes); Bacterial forms are designated as ATP synthase, Fo complex, subunit a; eukaryotic (chloroplast and mitochondrial) forms are designated as ATP synthase, Fo complex, subunit 6. The F-ATP synthases (also called FoF1-ATPases) consist of two structural domains: F1 (factor one) complex containing the soluble catalytic core, and Fo (oligomycin sensitive factor) complex containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. F-ATP synthases are primarily found in the inner membranes of eukaryotic mitochondria, in the thylakoid membranes of chloroplasts or in the plasma membranes of bacteria. F-ATP synthase has also been found in the archaea Methanosarcina acetivorans. F-ATP synthases are the primary producers of ATP, using the proton gradient generated by oxidative phosphorylation (mitochondria) or photosynthesis (chloroplasts). Alternatively, under conditions of low driving force, ATP synthases function as ATPases, thus generating a transmembrane proton or Na(+) gradient at the expense of energy derived from ATP hydrolysis.


Pssm-ID: 349411 [Multi-domain]  Cd Length: 156  Bit Score: 107.49  E-value: 6.80e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446057777  99 KLIAPLALTIFVWVFLMNLMDLLPIdllpyiaehwlglpatRVVPSADVNITLSMALGVFILILFYSIKMKGIGGFAKEL 178
Cdd:cd00310    2 KKYLPLLGTLFLFILFSNLLGLIPY----------------SFTPTSHLNVTLALALIVFLGVHILGIKKHGLGFFLHFL 65

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446057777 179 TLQPFnhWAFIPVNLILEGVSLLSKPVSLGLRLFGNMYAGELIFILIAGLLPWWSQW------ILNVPWAIFHILIITLQ 252
Cdd:cd00310   66 PPGTP--LPLAPLMVPIELISELIRPLSLSVRLFANMFAGHLLLALLSGLVPSLLSSvgllplLLPVALTLLELFVAFIQ 143

                        170
                 ....*....|...
gi 446057777 253 AFIFMVLTIVYLS 265
Cdd:cd00310  144 AYVFTLLTAVYIS 156
PRK13419 PRK13419
F0F1 ATP synthase subunit A; Provisional
 49-271 5.33e-22

F0F1 ATP synthase subunit A; Provisional


Pssm-ID: 237381  Cd Length: 342  Bit Score: 93.27  E-value: 5.33e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446057777  49 SVVLGLLFLVMFRSVAKKATSGVPGKFQTAIELIVGFVHGSV--KDMYHGKSKLIaPLALTIFVWVFLMNLMDLLPidll 126
Cdd:PRK13419 117 SAILLVVFLAAGRKYKKMTKSQAPKGLANAMEALVEFIRLDVakSNIGHGYEKFL-PYLLTVFFFILVCNLLGLVP---- 191

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446057777 127 pyiaehwLGLPATrvvpsADVNITLSMALGVFILILFYSIKMKGIGGFAKELTLQpfNHWAFIPVNLILEGVSLLSKPVS 206
Cdd:PRK13419 192 -------YGATAT-----GNINVTLTLAVFTFFITQYAAIKAHGIKGYLAHLTGG--THWSLWIIMIPIEFIGLFTKPFA 257

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 446057777 207 LGLRLFGNMYAGE-----LIFILIAgLLPWWSQWILNVPWAIF----HILIITLQAFIFMVLTIVYLSMASEEH 271
Cdd:PRK13419 258 LTVRLFANMTAGHivilsLIFISFI-LKSYIVAVAVSVPFAIFiyllELFVAFLQAYIFTMLSALFIGLATAHE 330
PRK13421 PRK13421
F0F1 ATP synthase subunit A; Provisional
 54-270 2.30e-16

F0F1 ATP synthase subunit A; Provisional


Pssm-ID: 237383  Cd Length: 223  Bit Score: 75.89  E-value: 2.30e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446057777  54 LLFLVMFRSVAKKATSGVPGKFQTAIELIVGFVHGSVKDMYHGKSKLIAPLALTIFVWVFLMNLMDLLPidllpyiaehw 133
Cdd:PRK13421  30 MAVLAAGSALATRRLSLAPGRLQSVLELVVTTIDAQIRDTMQTDPAPYRALIGTLFLFVLVANWSSLVP----------- 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446057777 134 lGLPAtrvvPSADVNITLSMALGVFILILFYSIKMKGIGGFakeltLQPFNH--WAFIPVNLilegVSLLSKPVSLGLRL 211
Cdd:PRK13421  99 -GVEP----PTAHLETDAALALIVFLATIYYGVRARGVRGY-----LATFAEptWVMIPLNL----VEQLTRTFSLIVRL 164

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446057777 212 FGNMYAGEL---IFILIAGLLpwwsqwiLNVPWAIFHILIITLQAFIFMVLTIVYLSMASEE 270
Cdd:PRK13421 165 FGNVMSGVFvigIVLSLAGLL-------VPIPLMALDLLTGAVQAYIFAVLAMVFIGAAVSD 219
PRK13420 PRK13420
F0F1 ATP synthase subunit A; Provisional
 54-271 2.32e-16

F0F1 ATP synthase subunit A; Provisional


Pssm-ID: 237382 [Multi-domain]  Cd Length: 226  Bit Score: 75.93  E-value: 2.32e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446057777  54 LLFLVMFRSVAKKATSGVPGKFQTAIELIVGFVHGSVKDMYHGKSKLIAPLALTIFVWVFLMNLMDLLPidllpyiaehw 133
Cdd:PRK13420  27 MIVLVLASWLTTRRLSLDPGRFQVALEGVVSTIEDAIKEVLPRHARLVLPFVGTLWIFILVANLIGLIP----------- 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446057777 134 lGLPAtrvvPSADVNITLSMALGVFILILFYSIKMKGIGGFAKE-LTLQPFnhwaFIPVNLILEgvslLSKPVSLGLRLF 212
Cdd:PRK13420  96 -GFHS----PTADLSVTAALALLVFFSVHWFGIRAEGLREYLKHyLSPSPF----LLPFHLISE----ITRTLALAVRLF 162

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 446057777 213 GNMYAGE---LIFILIAGLLpwwsqwiLNVPWAIFHILIITLQAFIFMVLTIVYLSMASEEH 271
Cdd:PRK13420 163 GNIMSLElaaLLVLLVAGFL-------VPVPILMLHIIEALVQAYIFGMLALIYIAGGIQAH 217
ATP6 MTH00172
ATP synthase F0 subunit 6; Provisional
 46-264 5.57e-08

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 214447  Cd Length: 232  Bit Score: 52.35  E-value: 5.57e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446057777  46 MFFSVVLGLLFLvmfrsvakKATSGVPGKFQTAIELIVGFVHGSVKDMYHGKSKLIAPLALTIFVWVFLMNLMDLLPIDL 125
Cdd:MTH00172  24 MILVIIVVLLLF--------KGIKLIPKRWQSIIEIIYNHFHGVVKDNLGNEGLKYFPFIISLFFFIVFLNLLGLFPYVF 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446057777 126 LPyiaehwlglpatrvvpsaDVNITLSMALGVFILIlfySIKMKGIGGFAKEL--TLQPFNH-WAFIPVNLILEGVSLLS 202
Cdd:MTH00172  96 TP------------------TTHIVVTLGLSFSIII---GVTLAGFWRFKWDFfsILMPSGApLGLAPLLVLIETVSYIS 154

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 446057777 203 KPVSLGLRLFGNMYAGELIFILIAGLLpwWSQWILNVPWAIFHILI---ITL--------QAFIFMVLTIVYL 264
Cdd:MTH00172 155 RAISLGVRLAANLSAGHLLFAILAGFG--FNMLCASGFLSLFPLLImvfITLleiavaviQAYVFCLLTTIYL 225
ATP6 MTH00176
ATP synthase F0 subunit 6; Provisional
 26-265 1.19e-07

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 214449  Cd Length: 229  Bit Score: 51.19  E-value: 1.19e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446057777  26 FSLVDPQNppatfwTLNIDSMFFSVVLGLLFLVMFRSVAKKATSGVPGKFQTAieliVGFVHGSVKDMYHGKSKLIAPLA 105
Cdd:MTH00176   6 FSSFDPPN------KNIFSMISLSWITLLLFLLLMPSSVWFCPSKLQVFMLMF----STFLPEMILRSNGSYILGSASII 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446057777 106 LTIFVWVFLMNLMDLLPIDLlpyiaehwlglpatrvVPSADVNITLSMALGVFILILFYSIKMKGIGGFAKELTLQpfNH 185
Cdd:MTH00176  76 ISLFILVMSLNLSGLIPYVF----------------TSTSHLVITLSLALPLWLGVILSGFINNFYSRLSHLVPQG--TP 137

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446057777 186 WAFIPVNLILEGVSLLSKPVSLGLRLFGNMYAGELIFILIA---------GLLPWWSQWILNVPWAIFHILIITLQAFIF 256
Cdd:MTH00176 138 PLLNPFLVLIELVSLLIRPLTLAVRLAANLSAGHLLLGLLGaamwgllpvSPLIGFLLLIVQILYFMFEIAVCMIQAYVF 217


                 ....*....
gi 446057777 257 MVLTIVYLS 265
Cdd:MTH00176 218 TLLLSLYLD 226
atpI CHL00046
ATP synthase CF0 A subunit
 50-263 1.20e-07

ATP synthase CF0 A subunit


Pssm-ID: 176987  Cd Length: 228  Bit Score: 51.09  E-value: 1.20e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446057777  50 VVLGLLFLVMFRSVAKKATsgVPGKFQTAIELIVGFVHGSVKD-MYHGKSKLIAPLALTIFVWVFLMNLMD-LLPIDLLP 127
Cdd:CHL00046  31 VVIAILLGSALLATRNLQT--IPTGGQNFFEYVLEFIRDLAKTqIGEEEYRPWVPFIGTMFLFIFVSNWSGaLLPWKLIE 108

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446057777 128 yiaehwlgLP-ATRVVPSADVNITLSMALGVFILILFYSIKMKGIGGFAKELTLQPFnhwaFIPVNlILEGvslLSKPVS 206
Cdd:CHL00046 109 --------LPhGELAAPTNDINTTVALALLTSVAYFYAGLSKKGLGYFGKYIQPTPI----LLPIN-ILED---FTKPLS 172

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 446057777 207 LGLRLFGNMYAGELIFILIAGLLPwwsqwiLNVPWAIFHILIIT--LQAFIFMVLTIVY 263
Cdd:CHL00046 173 LSFRLFGNILADELVVAVLVSLVP------LVVPIPVMFLGLFTsgIQALIFATLAAAY 225
ATP6 MTH00175
ATP synthase F0 subunit 6; Provisional
 71-265 2.46e-06

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 177228  Cd Length: 244  Bit Score: 47.31  E-value: 2.46e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446057777  71 VPGKFQTAIELIVGFVHGSVKDMYHGKSKLIAPLALTIFVWVFLMNLmdllpIDLLPYIaehwlglpatrVVPSADVNIT 150
Cdd:MTH00175  52 IPNRWQSIMELIYLNIRSVVHDNLGKSGQKYFPFILSLFLFIAILNI-----LGLFPYV-----------FTPTAHIIIT 115

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446057777 151 LSMALGVFILIL----------FYSIKMKGiggfAKELTLQPFNhwafipvnLILEGVSLLSKPVSLGLRLFGNMYAGEL 220
Cdd:MTH00175 116 FGLSLSIIIAVTllgfltfkwnFLSILMPG----GAPLVLAPFL--------VLIETLSYLIRAISLGVRLAANISAGHL 183

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 446057777 221 IFILIAG-----------LLPWWSQWILnVPWAIFHILIITLQAFIFMVLTIVYLS 265
Cdd:MTH00175 184 LFAILSGfafnmlsngliILSLFPMLIM-IFITLLEMAVAVIQAYVFCLLTTIYLG 238
PRK13417 PRK13417
F0F1 ATP synthase subunit A; Provisional
 71-271 1.21e-05

F0F1 ATP synthase subunit A; Provisional


Pssm-ID: 237380  Cd Length: 352  Bit Score: 46.04  E-value: 1.21e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446057777  71 VPGKFQTAIELIVGFVHGSVKD-MYHGKSKLIAPLALTIFVWVFLMNLMDLLP-------------------IDLLPYIA 130
Cdd:PRK13417 126 VQSRFANTVEVFVNFLRKDIVDeSMHGHGHSYYHYIFTLFFFILFCNLMGLVPsvgeltvvasdygglvalgVMDHTPHA 205

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446057777 131 EHWLGLPATRVVPSADVNITLSMALGVFILILFYSIKMKGIGGFAKELTLQ-PFNHWAFI-PVNLIlegVSLLSKPVSLG 208
Cdd:PRK13417 206 LPTFAKVWSGITVTGDISVTMTLALLTMFLIYGAGFSYQGPKFIWHSVPNGvPLLLYPIMwPLEFI---VSPMAKTFALT 282

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446057777 209 LRLFGNMYAGELIFILIAGLLPWWSQWIL-------NVPWAIFHILIITLQAFIFMVLTIVYLSMASEEH 271
Cdd:PRK13417 283 VRLLANMTAGHVIILALMGFIFQFQSWGIvpvsvigSGLIYVLEIFVAFLQAYIFVLLTSLFVGLSMHRH 352
ATP6 MTH00157
ATP synthase F0 subunit 6; Provisional
 35-265 1.84e-05

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 214441  Cd Length: 223  Bit Score: 44.77  E-value: 1.84e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446057777  35 PATFWTLNIDsmFFSVVLGLLFLVMFRSVakkatsgVPGKFQTAIELIVGFVHGSVKDMYHGKSKLIAPLALTIFVWVFL 114
Cdd:MTH00157  11 PSTSFNLSLN--WLSTFLGLLFIPSSFWL-------IPSRYNILWNKILKTLHKEFKTLLGPKNKGSTLIFISLFSFILF 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446057777 115 MNLMDLLPidllpYIaehwlglpatrVVPSADVNITLSMALGVFILILFYSIKMKgiggfakelTLQPFNHW-------A 187
Cdd:MTH00157  82 NNFLGLFP-----YI-----------FTSTSHLSLTLSLALPLWLSFMLFGWINN---------TNHMFAHLvpqgtppI 136

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446057777 188 FIPVNLILEGVSLLSKPVSLGLRLFGNMYAGELIFILIAGLLPWWSQWILNVPWaIFHILIITL-------QAFIFMVLT 260
Cdd:MTH00157 137 LMPFMVLIETISNLIRPGTLAVRLAANMIAGHLLLTLLGNTGPSLSSMILSILI-LIQILLLILesavaiiQSYVFSVLS 215


                 ....*
gi 446057777 261 IVYLS 265
Cdd:MTH00157 216 TLYSS 220
ATP6 MTH00173
ATP synthase F0 subunit 6; Provisional
 38-271 6.92e-04

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 214448  Cd Length: 231  Bit Score: 39.85  E-value: 6.92e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446057777  38 FWTLNIDSMFFSVVLGLLFLVMFRSVAKKATSGvpgkFQTAIELIVGFVHGSVKDMYHGKSKLIAPLALTIFVWVFLMNL 117
Cdd:MTH00173  12 HNSSFSSLSFLMWLLSLMSLFFFSSSVWVSSSN----LSSVFKLFVLTVSSQVTRSSGLNLGGFSLLLSSLFLFLISLNL 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446057777 118 mdllpIDLLPYIAEhwlglpatrvvPSADVNITLSMALGVFILILFYSIkMKGIGGFAKELtLQPFNHWAFIPVNLILEG 197
Cdd:MTH00173  88 -----SGLLPFVFS-----------VTSHLAFTFSLALPLWLSLILSGL-FYNPSKSLAGL-VPAGAPAGLNPFLVLIET 149

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446057777 198 VSLLSKPVSLGLRLFGNMYAGELIFILIAGLLP---WWSQW-------ILNVPWAIFHILIITLQAFIFMVLTIVYlsma 267
Cdd:MTH00173 150 VSILIRPLTLTVRLLANISAGHIVLTLIGNYLSsslFSSSVvslllvlLIQVGYFIFEVAVMLIQAYIFTLLIKLY---- 225


                 ....
gi 446057777 268 SEEH 271
Cdd:MTH00173 226 SDEH 229
ATP6 MTH00174
ATP synthase F0 subunit 6; Provisional
 55-271 2.26e-03

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 133799  Cd Length: 252  Bit Score: 38.77  E-value: 2.26e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446057777  55 LFLVMFRSVAKKATSGVPGKFQTAIELIVGFVHGSVKDMYHGKSKLIAPLALTIFVWVFLMNlmdllPIDLLPYIaehwl 134
Cdd:MTH00174  44 VFLFYTIGAKGNNNTLVPNRILVGLELIYSHFYTVLKDNLGNKGGNYLAFVLSLFILILFGN-----GLGLFPYV----- 113

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446057777 135 glpatrVVPSADVNITLSMALGVFILILFYSIKMKGIGGFAkeLTLQPFNHWAFIPVNLILEGVSLLSKPVSLGLRLFGN 214
Cdd:MTH00174 114 ------FTPTVHMVITLGLSFAIIVGTTLAGLITFRFNFFS--ILMPQGAPLALAPLLTIIETLSYISRAISLGVRLAAN 185

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446057777 215 MYAGELIFILIAGLL-PWWSQWILNVPWAIFHILIIT---------LQAFIFMVLTIVYLSMASEEH 271
Cdd:MTH00174 186 ISSGHLLFSIIASFAwKMINTGILIGSFVPFAILIFVtilemavaiIQAYVFTLLTIVYLRDTVELH 252
ATP6 MTH00132
ATP synthase F0 subunit 6; Provisional
 189-226 8.56e-03

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 177190  Cd Length: 227  Bit Score: 36.77  E-value: 8.56e-03
                         10        20        30
                 ....*....|....*....|....*....|....*...
gi 446057777 189 IPVNLILEGVSLLSKPVSLGLRLFGNMYAGELIFILIA 226
Cdd:MTH00132 139 IPVLIIIETISLFIRPLALGVRLTANLTAGHLLIQLIA 176
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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