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malate synthase G [Escherichia coli]
Protein Classification
malate synthase G ( domain architecture ID 10011891 )
malate synthase G catalyzes the formation of malate from glyoxylate and acetyl-CoA
List of domain hits
Name
Accession
Description
Interval
E-value
PRK02999
PRK02999 malate synthase G; Provisional
1-723
0e+00
malate synthase G; Provisional
Pssm-ID: 235097 [Multi-domain]
Cd Length: 726
Bit Score: 1464.24
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446006257 1 M SQTITQ G R L RID A NFKR FV DE E V LPG VEL DA A AFW RN F DQ IVHDLAP E NR Q LLA E RD RI QA AL D E WHR SN PGP VK D K AA 80
Cdd:PRK02999 1 M TERVQV G G L QVA A VLYD FV NN E A LPG TGV DA D AFW AG F AA IVHDLAP K NR A LLA K RD EL QA KI D A WHR AH PGP PH D L AA 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446006257 81 YK S FL R E L GYLVP Q PE RV T VE T TGI D S EI TS QAGPQLVVP A MNARYALNAANARWGSLYDALYG S D I IP Q EG AM -- VS GY 158
Cdd:PRK02999 81 YK A FL T E I GYLVP E PE DF T IT T ENV D P EI AT QAGPQLVVP V MNARYALNAANARWGSLYDALYG T D A IP E EG GA ek GK GY 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446006257 159 D P Q RG EQ VIA WV R R FLDE SL PL KN GS YQ DV VAFK V V D K QL RIQ LK N G K ET T L RT PAQFVGY R GD S AAP TC ILLKNNGLHI 238
Cdd:PRK02999 161 N P V RG AK VIA YA R A FLDE AA PL AS GS HA DV TGYA V E D G QL VVT LK D G S ET G L AD PAQFVGY Q GD A AAP SA ILLKNNGLHI 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446006257 239 E L QID A N GR IGK D DPA HIN DV IV E A A IS TI L DCEDSVAAVDAEDK I L L YRN L LGLM Q G T L Q E KM EK N G RQIV R K LN D DR Q 318
Cdd:PRK02999 241 E I QID R N HP IGK T DPA GVK DV VL E S A LT TI M DCEDSVAAVDAEDK V L V YRN W LGLM K G D L T E EF EK G G KTFT R R LN P DR E 320
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446006257 319 YTA A DG S E IS LHGRSLLF I RNVGHLMT I P V I W D SE GNEIPEGILD G V M T GA IAL Y DLK VQ --- K NSRTGSVYIVKPKMHG 395
Cdd:PRK02999 321 YTA P DG G E LT LHGRSLLF V RNVGHLMT N P A I L D AD GNEIPEGILD A V V T SL IAL H DLK GN grr R NSRTGSVYIVKPKMHG 400
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446006257 396 P Q EVAFAN K LF T R I E TM LG MAP NTLK M GIMDEERRTS L NL RS CI AQ A RN RV A FINTGFLDRTGDE M H SV MEAGPM L RK NQ 475
Cdd:PRK02999 401 P E EVAFAN E LF G R V E DL LG LPR NTLK V GIMDEERRTS V NL KA CI RA A KD RV V FINTGFLDRTGDE I H TS MEAGPM V RK GD 480
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446006257 476 MKS T PWI K AYE R NNV LS GL F CGLRG K AQIGKGMWAMPDLMADM YS QK GDQLR AGANTAWVPSPTAATLHALHYHQ TN V QS 555
Cdd:PRK02999 481 MKS S PWI A AYE D NNV DI GL A CGLRG R AQIGKGMWAMPDLMADM LE QK IAHPK AGANTAWVPSPTAATLHALHYHQ VD V FA 560
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446006257 556 VQA NI A Q T EFN A E fepl LDDLLTIP V AENANWS V EEIQQELDNN V QGILGYVVRWV E QG I GCSKVPDIH N V A LMEDRATL 635
Cdd:PRK02999 561 VQA EL A K T RPR A S ---- LDDLLTIP L AENANWS A EEIQQELDNN A QGILGYVVRWV D QG V GCSKVPDIH D V G LMEDRATL 636
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446006257 636 RISSQHIANWLRHG IL T K EQV QA SL EN MA K VVDQQNAGDPAYRPMA GN F A NS S AF K AA S DL I F L G VK QPNGYTEPLLHA W 715
Cdd:PRK02999 637 RISSQHIANWLRHG VV T E EQV ME SL KR MA A VVDQQNAGDPAYRPMA PD F D NS I AF Q AA C DL V F K G RE QPNGYTEPLLHA R 716
....*...
gi 446006257 716 RL RE K ESH 723
Cdd:PRK02999 717 RL EA K AKQ 724
Name
Accession
Description
Interval
E-value
PRK02999
PRK02999 malate synthase G; Provisional
1-723
0e+00
malate synthase G; Provisional
Pssm-ID: 235097 [Multi-domain]
Cd Length: 726
Bit Score: 1464.24
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446006257 1 M SQTITQ G R L RID A NFKR FV DE E V LPG VEL DA A AFW RN F DQ IVHDLAP E NR Q LLA E RD RI QA AL D E WHR SN PGP VK D K AA 80
Cdd:PRK02999 1 M TERVQV G G L QVA A VLYD FV NN E A LPG TGV DA D AFW AG F AA IVHDLAP K NR A LLA K RD EL QA KI D A WHR AH PGP PH D L AA 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446006257 81 YK S FL R E L GYLVP Q PE RV T VE T TGI D S EI TS QAGPQLVVP A MNARYALNAANARWGSLYDALYG S D I IP Q EG AM -- VS GY 158
Cdd:PRK02999 81 YK A FL T E I GYLVP E PE DF T IT T ENV D P EI AT QAGPQLVVP V MNARYALNAANARWGSLYDALYG T D A IP E EG GA ek GK GY 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446006257 159 D P Q RG EQ VIA WV R R FLDE SL PL KN GS YQ DV VAFK V V D K QL RIQ LK N G K ET T L RT PAQFVGY R GD S AAP TC ILLKNNGLHI 238
Cdd:PRK02999 161 N P V RG AK VIA YA R A FLDE AA PL AS GS HA DV TGYA V E D G QL VVT LK D G S ET G L AD PAQFVGY Q GD A AAP SA ILLKNNGLHI 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446006257 239 E L QID A N GR IGK D DPA HIN DV IV E A A IS TI L DCEDSVAAVDAEDK I L L YRN L LGLM Q G T L Q E KM EK N G RQIV R K LN D DR Q 318
Cdd:PRK02999 241 E I QID R N HP IGK T DPA GVK DV VL E S A LT TI M DCEDSVAAVDAEDK V L V YRN W LGLM K G D L T E EF EK G G KTFT R R LN P DR E 320
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446006257 319 YTA A DG S E IS LHGRSLLF I RNVGHLMT I P V I W D SE GNEIPEGILD G V M T GA IAL Y DLK VQ --- K NSRTGSVYIVKPKMHG 395
Cdd:PRK02999 321 YTA P DG G E LT LHGRSLLF V RNVGHLMT N P A I L D AD GNEIPEGILD A V V T SL IAL H DLK GN grr R NSRTGSVYIVKPKMHG 400
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446006257 396 P Q EVAFAN K LF T R I E TM LG MAP NTLK M GIMDEERRTS L NL RS CI AQ A RN RV A FINTGFLDRTGDE M H SV MEAGPM L RK NQ 475
Cdd:PRK02999 401 P E EVAFAN E LF G R V E DL LG LPR NTLK V GIMDEERRTS V NL KA CI RA A KD RV V FINTGFLDRTGDE I H TS MEAGPM V RK GD 480
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446006257 476 MKS T PWI K AYE R NNV LS GL F CGLRG K AQIGKGMWAMPDLMADM YS QK GDQLR AGANTAWVPSPTAATLHALHYHQ TN V QS 555
Cdd:PRK02999 481 MKS S PWI A AYE D NNV DI GL A CGLRG R AQIGKGMWAMPDLMADM LE QK IAHPK AGANTAWVPSPTAATLHALHYHQ VD V FA 560
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446006257 556 VQA NI A Q T EFN A E fepl LDDLLTIP V AENANWS V EEIQQELDNN V QGILGYVVRWV E QG I GCSKVPDIH N V A LMEDRATL 635
Cdd:PRK02999 561 VQA EL A K T RPR A S ---- LDDLLTIP L AENANWS A EEIQQELDNN A QGILGYVVRWV D QG V GCSKVPDIH D V G LMEDRATL 636
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446006257 636 RISSQHIANWLRHG IL T K EQV QA SL EN MA K VVDQQNAGDPAYRPMA GN F A NS S AF K AA S DL I F L G VK QPNGYTEPLLHA W 715
Cdd:PRK02999 637 RISSQHIANWLRHG VV T E EQV ME SL KR MA A VVDQQNAGDPAYRPMA PD F D NS I AF Q AA C DL V F K G RE QPNGYTEPLLHA R 716
....*...
gi 446006257 716 RL RE K ESH 723
Cdd:PRK02999 717 RL EA K AKQ 724
malate_synt_G
cd00728 Malate synthase G (MSG), monomeric enzyme present in some bacteria. In general, malate ...
9-720
0e+00
Malate synthase G (MSG), monomeric enzyme present in some bacteria. In general, malate synthase catalyzes the Claisen condensation of glyoxylate and acetyl-CoA to malyl-CoA , which hydrolyzes to malate and CoA. This reaction is part of the glyoxylate cycle, which allows certain organisms to derive their carbon requirements from two-carbon compounds, by bypassing the two carboxylation steps of the citric acid cycle.
Pssm-ID: 238370 [Multi-domain]
Cd Length: 712
Bit Score: 1406.78
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446006257 9 R LR IDANFKR FV D EE V LPG VEL DA A AFW RN FD Q IVHDL A P E NR Q LLA E RD RI QA AL D E WHR S NPGP VK D K AAYK S FL R E L 88
Cdd:cd00728 1 N LR VAGCLYD FV N EE A LPG TGI DA D AFW AG FD E IVHDL T P R NR A LLA K RD EL QA KI D D WHR D NPGP PL D Q AAYK K FL K E I 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446006257 89 GYLVP Q P ERV T VE T TGI D S EI TS QAGPQLVVP A MNARYALNAANARWGSLYDALYG S D I IP Q E GAM -- VS GY D P Q RG EQ V 166
Cdd:cd00728 81 GYLVP E P ADF T IT T DNV D D EI AT QAGPQLVVP L MNARYALNAANARWGSLYDALYG T D V IP E E NGA er GK GY N P V RG AK V 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446006257 167 IA WV RRFLDES L PL K NGS YQ D VVAF KVVD K QL RIQ L KN GK E TTL RT PAQFVGYRGD SA AP TCI LLK N NGLHIE L QID A N G 246
Cdd:cd00728 161 IA YA RRFLDES V PL T NGS HA D ATGY KVVD G QL VVT L DD GK T TTL KD PAQFVGYRGD AN AP SAV LLK H NGLHIE I QID R N H 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446006257 247 R IGK D DPA HIN DV I VEAA IS TI L DCEDSVAAVDAEDK I L L YRN L LGLM Q G T L Q E KM EKNGR QIV RKLN D DR Q YT AA DG S E 326
Cdd:cd00728 241 Q IGK T DPA GVK DV V VEAA LT TI M DCEDSVAAVDAEDK V L V YRN W LGLM K G D L A E EV EKNGR TFT RKLN A DR N YT TP DG G E 320
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446006257 327 I S L H GRSL L F I RNVGHLMT IPV I W DS E GNE I PEGI L D G V M T GA IAL Y DLK V --- QK NSRTGS V YIVKPKMHGP Q EVAFAN 403
Cdd:cd00728 321 I T L P GRSL M F V RNVGHLMT NDA I L DS D GNE V PEGI M D A V I T SL IAL H DLK G nsa FG NSRTGS I YIVKPKMHGP E EVAFAN 400
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446006257 404 K LF T R I E TM LG MAP NT L KMGIMDEERRTS L NL RS CI AQ AR N RV A FINTGFLDRTGDE M H SV MEAGPM L RK NQ MKS T PWI K 483
Cdd:cd00728 401 E LF S R V E DL LG LPQ NT I KMGIMDEERRTS V NL KE CI RA AR D RV V FINTGFLDRTGDE I H TS MEAGPM A RK AD MKS S PWI G 480
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446006257 484 AYE R NNV LS GL FC GL R GKAQIGKGMWAMPDLMADM YS QK GDQLR AGANTAWVPSPTAATLHALHYHQ T NV QS VQ ANI A QT 563
Cdd:cd00728 481 AYE D NNV DI GL AA GL S GKAQIGKGMWAMPDLMADM ME QK IAHPK AGANTAWVPSPTAATLHALHYHQ V NV FA VQ KEL A KR 560
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446006257 564 EF naefe PL LDDLLTIP V AENANWS VE EIQ Q ELDNNVQGILGYVVRWV E QGIGCSKVPDI H NV A LMEDRATLRISSQHIA 643
Cdd:cd00728 561 RP ----- AD LDDLLTIP L AENANWS PQ EIQ S ELDNNVQGILGYVVRWV D QGIGCSKVPDI N NV G LMEDRATLRISSQHIA 635
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446006257 644 NWLRHGI L TKEQVQ A SLE N MAKVVDQQNAGDP A YRPMA GN F AN S S AFKAA S DLIF L G VK QPNGYTEPLLHA W RL RE K 720
Cdd:cd00728 636 NWLRHGI C TKEQVQ E SLE R MAKVVDQQNAGDP S YRPMA PD F DD S I AFKAA C DLIF Q G KE QPNGYTEPLLHA R RL EK K 712
malate_syn_G
TIGR01345 malate synthase G; This model describes the G isozyme of malate synthase. Isocitrate synthase ...
3-723
0e+00
malate synthase G; This model describes the G isozyme of malate synthase. Isocitrate synthase and malate synthase form the glyoxylate shunt, which generates additional TCA cycle intermediates. [Energy metabolism, TCA cycle]
Pssm-ID: 130412 [Multi-domain]
Cd Length: 721
Bit Score: 1398.89
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446006257 3 QTITQGRL RID AN F KRFVDEEVLPG VE LDAAAFW RN FD Q IVHDLAPENRQLLAERD R IQAA L DEWHRSNPGP v K DKAAYK 82
Cdd:TIGR01345 1 QTITQGRL QVA AN L KRFVDEEVLPG TG LDAAAFW SG FD E IVHDLAPENRQLLAERD E IQAA I DEWHRSNPGP - I DKAAYK 79
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446006257 83 SFLRE L GYLVPQPERVT V ETT GI DSEITSQAGPQLVVPAMNARYALNAANARWGSLYDALYGS D IIP Q E GA M VS G -- Y D P 160
Cdd:TIGR01345 80 SFLRE I GYLVPQPERVT I ETT NV DSEITSQAGPQLVVPAMNARYALNAANARWGSLYDALYGS N IIP E E DG M EK G ke Y N P 159
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446006257 161 QRGE Q VIAWVRRFLDESLPL K NGS Y QDVVA F K V VDKQLRIQLKNGKET T L R TPAQFVGYRGD S A A PTCILLKNNGLHIEL 240
Cdd:TIGR01345 160 QRGE K VIAWVRRFLDESLPL E NGS H QDVVA Y K I VDKQLRIQLKNGKET R L K TPAQFVGYRGD A A D PTCILLKNNGLHIEL 239
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446006257 241 QIDAN GR IGKDDPAHI N D VIV E A AI S TI L DCEDSVAAVDAEDKILLYRN L LGLMQGTLQEKMEKNGRQIVRKLNDDR Q YT 320
Cdd:TIGR01345 240 QIDAN HP IGKDDPAHI K D IVL E S AI T TI M DCEDSVAAVDAEDKILLYRN W LGLMQGTLQEKMEKNGRQIVRKLNDDR H YT 319
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446006257 321 AA D GSEISLHGRSLLF I RNVGHLMTIPVIWDSEG N EIPEGILDGVMTGAIALYDLKVQ --- K NSR T GSVYIVKPKMHGP Q 397
Cdd:TIGR01345 320 AA N GSEISLHGRSLLF V RNVGHLMTIPVIWDSEG E EIPEGILDGVMTGAIALYDLKVQ nkm R NSR K GSVYIVKPKMHGP E 399
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446006257 398 EVAFANKLFTRIE T MLG M A PN TLKMG I MDEERRTSLNLR S CIAQ A RNRVAFINTGFLDRTGDE M H SV MEAGPMLRKN Q MK 477
Cdd:TIGR01345 400 EVAFANKLFTRIE D MLG L A RH TLKMG V MDEERRTSLNLR A CIAQ V RNRVAFINTGFLDRTGDE I H TS MEAGPMLRKN D MK 479
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446006257 478 STPWIKAYERNNVL S GLFCGLRGKAQIGKGMWAMPDLMA D MY S QKGDQLRAGANTAWVPSPTAATLHALHYHQTNVQSVQ 557
Cdd:TIGR01345 480 STPWIKAYERNNVL A GLFCGLRGKAQIGKGMWAMPDLMA E MY E QKGDQLRAGANTAWVPSPTAATLHALHYHQTNVQSVQ 559
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446006257 558 AN I AQTEFNAE fepl LDD L LTIPVAEN A NWS V EEIQQELDNNVQGILGYVVRWVEQGIGCSKVPDIHNVALMEDRATLRI 637
Cdd:TIGR01345 560 AN L AQTEFNAE ---- LDD I LTIPVAEN T NWS A EEIQQELDNNVQGILGYVVRWVEQGIGCSKVPDIHNVALMEDRATLRI 635
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446006257 638 SSQHIANWLRHGI LT KEQVQASLE N MAKVVDQQNAGDPAYRPMAGNFANS S AF K AASDLIFLG V KQP N GYTEP L LHA W RL 717
Cdd:TIGR01345 636 SSQHIANWLRHGI VS KEQVQASLE R MAKVVDQQNAGDPAYRPMAGNFANS C AF Q AASDLIFLG T KQP S GYTEP I LHA R RL 715
....*.
gi 446006257 718 RE KE S H 723
Cdd:TIGR01345 716 EF KE K H 721
Malate_synthase
pfam01274 Malate synthase;
17-697
0e+00
Malate synthase;
Pssm-ID: 426172
Cd Length: 523
Bit Score: 606.31
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446006257 17 KR FV DEE VLPG VELDAAAFWRNFDQIVH D LA P EN R Q LLA E RD RI QA AL D EW H rsnpgpvkdkaa YKS FL R E L GY LV P Q P E 96
Cdd:pfam01274 1 YD FV GPY VLPG TGILTKEALSFVAELHR D FT P RR R E LLA R RD ER QA RI D AG H ------------ LPD FL P E T GY IR P D P D 68
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446006257 97 RV T vettgidseitsqagpqlvvpamnaryalnaanarwgslydalygsdiipqegamvsgydpqrgeqviawvrrflde 176
Cdd:pfam01274 69 WK T ----------------------------------------------------------------------------- 71
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446006257 177 slplkngsyqdvvafkvvdkqlriqlkngkettlrtpaqfvgyrgdsaaptcillkn NG LH I ELQ IDANGRI G KD D PAH I 256
Cdd:pfam01274 72 --------------------------------------------------------- AT LH P ELQ DRRVEIT G PA D RKM I 94
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446006257 257 NDVIVEA AI S T IL D C EDSVA A vdaedkillyr NLLG L M QG T L QEKMEKN GR QIV R K LN DDRQ Y TAA DG seis LHGR SL LF 336
Cdd:pfam01274 95 INALNSG AI T T MA D F EDSVA P ----------- TWNN L I QG Q L NLYDAVR GR IDF R D LN AGKS Y KLN DG ---- LHGR AT LF 159
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446006257 337 I R NV G HLMTIPV I W d SE G NE IP E GI L D G vmt G AIALYDL K VQ k NSR T G SV Y IVK PKM HGP QE V A FA N KL F T R I E TM LG MA 416
Cdd:pfam01274 160 V R PR G WHLPEKH I L - VD G EP IP G GI F D F --- G LYFFHNA K EL - NSR G G GP Y FYL PKM EHH QE A A LW N DV F N R A E DY LG IP 234
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446006257 417 PN T LKMGIMD E ERRT S LNLRSC I AQA R NRV A FI N T G FL D RTGDEMHSVME A GP M L --- RK NQMKST P WIK AYE RNNVLS - 492
Cdd:pfam01274 235 RG T IRATVLI E TLPA S FQMDEI I YEL R DHS A GL N C G RW D YIFSYIKTLRN A PD M V lpd RK AVTMTA P FMR AYE KLLIKT c 314
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446006257 493 ----- GLFC G LRGKAQ I GKG M W A MPDL M ADMYSQ K GDQL RAG ANTA WV PS P TA A T L H A LHY HQ TN V QSV Q ANI A QT E FNA 567
Cdd:pfam01274 315 hkrgv HAMG G MAAQIP I KDD M E A NTAA M EKVRAD K LREV RAG HDGT WV AH P GL A P L A A EVF HQ VM V RPN Q IEL A RE E DSI 394
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446006257 568 E fepl L DDLLTIP VA enanwsv EE IQQE L D NN V Q GI L G YV VR W V e Q G I GC sk VP D IH nva LMED R AT LR IS S Q HIAN WLR 647
Cdd:pfam01274 395 T ---- A DDLLTIP DG ------- EE TEEG L R NN I Q VG L Q YV EA W L - R G S GC -- VP I IH --- LMED A AT AE IS R Q QLWQ WLR 457
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446006257 648 HG ILTK E Q V QAS LE N MAK V VD QQ NA ------- GD P AYR PM --------- A GNFANSSAFK A AS DLI 697
Cdd:pfam01274 458 HG VTLD E G V RVT LE L MAK L VD EE NA rlakerf GD G AYR DA arlflqqat A EEYDDFLTLL A YD DLI 523
AceB
COG2225 Malate synthase [Energy production and conversion]; Malate synthase is part of the Pathway ...
574-697
4.43e-05
Malate synthase [Energy production and conversion]; Malate synthase is part of the Pathway/BioSystem: TCA cycle, glyoxylate bypass
Pssm-ID: 441827
Cd Length: 530
Bit Score: 46.64
E-value: 4.43e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446006257 574 D DLL TI P VAE nanws VE E iq QE L D NN VQGILG Y VVR W V e Q G I G C sk VP d I H N va LMED R AT LR IS - SQ h IAN W LR HG --- 649
Cdd:COG2225 400 A DLL DV P EGT ----- IT E -- AG L R NN ISVGIQ Y LEA W L - R G N G A -- VP - I Y N -- LMED A AT AE IS r SQ - VWQ W IH HG atl 465
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|...
gi 446006257 650 ---- IL T K E Q V QAS L - E NM AK V vd QQNA G DPAY rpmagnfa NSSA F KA A SD L I 697
Cdd:COG2225 466 ddgr KV T A E L V RQL L a E EL AK L -- RAEV G EERF -------- EAGR F DE A AE L F 508
Name
Accession
Description
Interval
E-value
PRK02999
PRK02999 malate synthase G; Provisional
1-723
0e+00
malate synthase G; Provisional
Pssm-ID: 235097 [Multi-domain]
Cd Length: 726
Bit Score: 1464.24
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446006257 1 M SQTITQ G R L RID A NFKR FV DE E V LPG VEL DA A AFW RN F DQ IVHDLAP E NR Q LLA E RD RI QA AL D E WHR SN PGP VK D K AA 80
Cdd:PRK02999 1 M TERVQV G G L QVA A VLYD FV NN E A LPG TGV DA D AFW AG F AA IVHDLAP K NR A LLA K RD EL QA KI D A WHR AH PGP PH D L AA 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446006257 81 YK S FL R E L GYLVP Q PE RV T VE T TGI D S EI TS QAGPQLVVP A MNARYALNAANARWGSLYDALYG S D I IP Q EG AM -- VS GY 158
Cdd:PRK02999 81 YK A FL T E I GYLVP E PE DF T IT T ENV D P EI AT QAGPQLVVP V MNARYALNAANARWGSLYDALYG T D A IP E EG GA ek GK GY 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446006257 159 D P Q RG EQ VIA WV R R FLDE SL PL KN GS YQ DV VAFK V V D K QL RIQ LK N G K ET T L RT PAQFVGY R GD S AAP TC ILLKNNGLHI 238
Cdd:PRK02999 161 N P V RG AK VIA YA R A FLDE AA PL AS GS HA DV TGYA V E D G QL VVT LK D G S ET G L AD PAQFVGY Q GD A AAP SA ILLKNNGLHI 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446006257 239 E L QID A N GR IGK D DPA HIN DV IV E A A IS TI L DCEDSVAAVDAEDK I L L YRN L LGLM Q G T L Q E KM EK N G RQIV R K LN D DR Q 318
Cdd:PRK02999 241 E I QID R N HP IGK T DPA GVK DV VL E S A LT TI M DCEDSVAAVDAEDK V L V YRN W LGLM K G D L T E EF EK G G KTFT R R LN P DR E 320
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446006257 319 YTA A DG S E IS LHGRSLLF I RNVGHLMT I P V I W D SE GNEIPEGILD G V M T GA IAL Y DLK VQ --- K NSRTGSVYIVKPKMHG 395
Cdd:PRK02999 321 YTA P DG G E LT LHGRSLLF V RNVGHLMT N P A I L D AD GNEIPEGILD A V V T SL IAL H DLK GN grr R NSRTGSVYIVKPKMHG 400
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446006257 396 P Q EVAFAN K LF T R I E TM LG MAP NTLK M GIMDEERRTS L NL RS CI AQ A RN RV A FINTGFLDRTGDE M H SV MEAGPM L RK NQ 475
Cdd:PRK02999 401 P E EVAFAN E LF G R V E DL LG LPR NTLK V GIMDEERRTS V NL KA CI RA A KD RV V FINTGFLDRTGDE I H TS MEAGPM V RK GD 480
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446006257 476 MKS T PWI K AYE R NNV LS GL F CGLRG K AQIGKGMWAMPDLMADM YS QK GDQLR AGANTAWVPSPTAATLHALHYHQ TN V QS 555
Cdd:PRK02999 481 MKS S PWI A AYE D NNV DI GL A CGLRG R AQIGKGMWAMPDLMADM LE QK IAHPK AGANTAWVPSPTAATLHALHYHQ VD V FA 560
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446006257 556 VQA NI A Q T EFN A E fepl LDDLLTIP V AENANWS V EEIQQELDNN V QGILGYVVRWV E QG I GCSKVPDIH N V A LMEDRATL 635
Cdd:PRK02999 561 VQA EL A K T RPR A S ---- LDDLLTIP L AENANWS A EEIQQELDNN A QGILGYVVRWV D QG V GCSKVPDIH D V G LMEDRATL 636
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446006257 636 RISSQHIANWLRHG IL T K EQV QA SL EN MA K VVDQQNAGDPAYRPMA GN F A NS S AF K AA S DL I F L G VK QPNGYTEPLLHA W 715
Cdd:PRK02999 637 RISSQHIANWLRHG VV T E EQV ME SL KR MA A VVDQQNAGDPAYRPMA PD F D NS I AF Q AA C DL V F K G RE QPNGYTEPLLHA R 716
....*...
gi 446006257 716 RL RE K ESH 723
Cdd:PRK02999 717 RL EA K AKQ 724
malate_synt_G
cd00728 Malate synthase G (MSG), monomeric enzyme present in some bacteria. In general, malate ...
9-720
0e+00
Malate synthase G (MSG), monomeric enzyme present in some bacteria. In general, malate synthase catalyzes the Claisen condensation of glyoxylate and acetyl-CoA to malyl-CoA , which hydrolyzes to malate and CoA. This reaction is part of the glyoxylate cycle, which allows certain organisms to derive their carbon requirements from two-carbon compounds, by bypassing the two carboxylation steps of the citric acid cycle.
Pssm-ID: 238370 [Multi-domain]
Cd Length: 712
Bit Score: 1406.78
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446006257 9 R LR IDANFKR FV D EE V LPG VEL DA A AFW RN FD Q IVHDL A P E NR Q LLA E RD RI QA AL D E WHR S NPGP VK D K AAYK S FL R E L 88
Cdd:cd00728 1 N LR VAGCLYD FV N EE A LPG TGI DA D AFW AG FD E IVHDL T P R NR A LLA K RD EL QA KI D D WHR D NPGP PL D Q AAYK K FL K E I 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446006257 89 GYLVP Q P ERV T VE T TGI D S EI TS QAGPQLVVP A MNARYALNAANARWGSLYDALYG S D I IP Q E GAM -- VS GY D P Q RG EQ V 166
Cdd:cd00728 81 GYLVP E P ADF T IT T DNV D D EI AT QAGPQLVVP L MNARYALNAANARWGSLYDALYG T D V IP E E NGA er GK GY N P V RG AK V 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446006257 167 IA WV RRFLDES L PL K NGS YQ D VVAF KVVD K QL RIQ L KN GK E TTL RT PAQFVGYRGD SA AP TCI LLK N NGLHIE L QID A N G 246
Cdd:cd00728 161 IA YA RRFLDES V PL T NGS HA D ATGY KVVD G QL VVT L DD GK T TTL KD PAQFVGYRGD AN AP SAV LLK H NGLHIE I QID R N H 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446006257 247 R IGK D DPA HIN DV I VEAA IS TI L DCEDSVAAVDAEDK I L L YRN L LGLM Q G T L Q E KM EKNGR QIV RKLN D DR Q YT AA DG S E 326
Cdd:cd00728 241 Q IGK T DPA GVK DV V VEAA LT TI M DCEDSVAAVDAEDK V L V YRN W LGLM K G D L A E EV EKNGR TFT RKLN A DR N YT TP DG G E 320
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446006257 327 I S L H GRSL L F I RNVGHLMT IPV I W DS E GNE I PEGI L D G V M T GA IAL Y DLK V --- QK NSRTGS V YIVKPKMHGP Q EVAFAN 403
Cdd:cd00728 321 I T L P GRSL M F V RNVGHLMT NDA I L DS D GNE V PEGI M D A V I T SL IAL H DLK G nsa FG NSRTGS I YIVKPKMHGP E EVAFAN 400
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446006257 404 K LF T R I E TM LG MAP NT L KMGIMDEERRTS L NL RS CI AQ AR N RV A FINTGFLDRTGDE M H SV MEAGPM L RK NQ MKS T PWI K 483
Cdd:cd00728 401 E LF S R V E DL LG LPQ NT I KMGIMDEERRTS V NL KE CI RA AR D RV V FINTGFLDRTGDE I H TS MEAGPM A RK AD MKS S PWI G 480
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446006257 484 AYE R NNV LS GL FC GL R GKAQIGKGMWAMPDLMADM YS QK GDQLR AGANTAWVPSPTAATLHALHYHQ T NV QS VQ ANI A QT 563
Cdd:cd00728 481 AYE D NNV DI GL AA GL S GKAQIGKGMWAMPDLMADM ME QK IAHPK AGANTAWVPSPTAATLHALHYHQ V NV FA VQ KEL A KR 560
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446006257 564 EF naefe PL LDDLLTIP V AENANWS VE EIQ Q ELDNNVQGILGYVVRWV E QGIGCSKVPDI H NV A LMEDRATLRISSQHIA 643
Cdd:cd00728 561 RP ----- AD LDDLLTIP L AENANWS PQ EIQ S ELDNNVQGILGYVVRWV D QGIGCSKVPDI N NV G LMEDRATLRISSQHIA 635
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 446006257 644 NWLRHGI L TKEQVQ A SLE N MAKVVDQQNAGDP A YRPMA GN F AN S S AFKAA S DLIF L G VK QPNGYTEPLLHA W RL RE K 720
Cdd:cd00728 636 NWLRHGI C TKEQVQ E SLE R MAKVVDQQNAGDP S YRPMA PD F DD S I AFKAA C DLIF Q G KE QPNGYTEPLLHA R RL EK K 712
malate_syn_G
TIGR01345 malate synthase G; This model describes the G isozyme of malate synthase. Isocitrate synthase ...
3-723
0e+00
malate synthase G; This model describes the G isozyme of malate synthase. Isocitrate synthase and malate synthase form the glyoxylate shunt, which generates additional TCA cycle intermediates. [Energy metabolism, TCA cycle]
Pssm-ID: 130412 [Multi-domain]
Cd Length: 721
Bit Score: 1398.89
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446006257 3 QTITQGRL RID AN F KRFVDEEVLPG VE LDAAAFW RN FD Q IVHDLAPENRQLLAERD R IQAA L DEWHRSNPGP v K DKAAYK 82
Cdd:TIGR01345 1 QTITQGRL QVA AN L KRFVDEEVLPG TG LDAAAFW SG FD E IVHDLAPENRQLLAERD E IQAA I DEWHRSNPGP - I DKAAYK 79
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446006257 83 SFLRE L GYLVPQPERVT V ETT GI DSEITSQAGPQLVVPAMNARYALNAANARWGSLYDALYGS D IIP Q E GA M VS G -- Y D P 160
Cdd:TIGR01345 80 SFLRE I GYLVPQPERVT I ETT NV DSEITSQAGPQLVVPAMNARYALNAANARWGSLYDALYGS N IIP E E DG M EK G ke Y N P 159
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446006257 161 QRGE Q VIAWVRRFLDESLPL K NGS Y QDVVA F K V VDKQLRIQLKNGKET T L R TPAQFVGYRGD S A A PTCILLKNNGLHIEL 240
Cdd:TIGR01345 160 QRGE K VIAWVRRFLDESLPL E NGS H QDVVA Y K I VDKQLRIQLKNGKET R L K TPAQFVGYRGD A A D PTCILLKNNGLHIEL 239
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446006257 241 QIDAN GR IGKDDPAHI N D VIV E A AI S TI L DCEDSVAAVDAEDKILLYRN L LGLMQGTLQEKMEKNGRQIVRKLNDDR Q YT 320
Cdd:TIGR01345 240 QIDAN HP IGKDDPAHI K D IVL E S AI T TI M DCEDSVAAVDAEDKILLYRN W LGLMQGTLQEKMEKNGRQIVRKLNDDR H YT 319
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446006257 321 AA D GSEISLHGRSLLF I RNVGHLMTIPVIWDSEG N EIPEGILDGVMTGAIALYDLKVQ --- K NSR T GSVYIVKPKMHGP Q 397
Cdd:TIGR01345 320 AA N GSEISLHGRSLLF V RNVGHLMTIPVIWDSEG E EIPEGILDGVMTGAIALYDLKVQ nkm R NSR K GSVYIVKPKMHGP E 399
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446006257 398 EVAFANKLFTRIE T MLG M A PN TLKMG I MDEERRTSLNLR S CIAQ A RNRVAFINTGFLDRTGDE M H SV MEAGPMLRKN Q MK 477
Cdd:TIGR01345 400 EVAFANKLFTRIE D MLG L A RH TLKMG V MDEERRTSLNLR A CIAQ V RNRVAFINTGFLDRTGDE I H TS MEAGPMLRKN D MK 479
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446006257 478 STPWIKAYERNNVL S GLFCGLRGKAQIGKGMWAMPDLMA D MY S QKGDQLRAGANTAWVPSPTAATLHALHYHQTNVQSVQ 557
Cdd:TIGR01345 480 STPWIKAYERNNVL A GLFCGLRGKAQIGKGMWAMPDLMA E MY E QKGDQLRAGANTAWVPSPTAATLHALHYHQTNVQSVQ 559
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446006257 558 AN I AQTEFNAE fepl LDD L LTIPVAEN A NWS V EEIQQELDNNVQGILGYVVRWVEQGIGCSKVPDIHNVALMEDRATLRI 637
Cdd:TIGR01345 560 AN L AQTEFNAE ---- LDD I LTIPVAEN T NWS A EEIQQELDNNVQGILGYVVRWVEQGIGCSKVPDIHNVALMEDRATLRI 635
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446006257 638 SSQHIANWLRHGI LT KEQVQASLE N MAKVVDQQNAGDPAYRPMAGNFANS S AF K AASDLIFLG V KQP N GYTEP L LHA W RL 717
Cdd:TIGR01345 636 SSQHIANWLRHGI VS KEQVQASLE R MAKVVDQQNAGDPAYRPMAGNFANS C AF Q AASDLIFLG T KQP S GYTEP I LHA R RL 715
....*.
gi 446006257 718 RE KE S H 723
Cdd:TIGR01345 716 EF KE K H 721
Malate_synthase
pfam01274 Malate synthase;
17-697
0e+00
Malate synthase;
Pssm-ID: 426172
Cd Length: 523
Bit Score: 606.31
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446006257 17 KR FV DEE VLPG VELDAAAFWRNFDQIVH D LA P EN R Q LLA E RD RI QA AL D EW H rsnpgpvkdkaa YKS FL R E L GY LV P Q P E 96
Cdd:pfam01274 1 YD FV GPY VLPG TGILTKEALSFVAELHR D FT P RR R E LLA R RD ER QA RI D AG H ------------ LPD FL P E T GY IR P D P D 68
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446006257 97 RV T vettgidseitsqagpqlvvpamnaryalnaanarwgslydalygsdiipqegamvsgydpqrgeqviawvrrflde 176
Cdd:pfam01274 69 WK T ----------------------------------------------------------------------------- 71
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446006257 177 slplkngsyqdvvafkvvdkqlriqlkngkettlrtpaqfvgyrgdsaaptcillkn NG LH I ELQ IDANGRI G KD D PAH I 256
Cdd:pfam01274 72 --------------------------------------------------------- AT LH P ELQ DRRVEIT G PA D RKM I 94
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446006257 257 NDVIVEA AI S T IL D C EDSVA A vdaedkillyr NLLG L M QG T L QEKMEKN GR QIV R K LN DDRQ Y TAA DG seis LHGR SL LF 336
Cdd:pfam01274 95 INALNSG AI T T MA D F EDSVA P ----------- TWNN L I QG Q L NLYDAVR GR IDF R D LN AGKS Y KLN DG ---- LHGR AT LF 159
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446006257 337 I R NV G HLMTIPV I W d SE G NE IP E GI L D G vmt G AIALYDL K VQ k NSR T G SV Y IVK PKM HGP QE V A FA N KL F T R I E TM LG MA 416
Cdd:pfam01274 160 V R PR G WHLPEKH I L - VD G EP IP G GI F D F --- G LYFFHNA K EL - NSR G G GP Y FYL PKM EHH QE A A LW N DV F N R A E DY LG IP 234
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446006257 417 PN T LKMGIMD E ERRT S LNLRSC I AQA R NRV A FI N T G FL D RTGDEMHSVME A GP M L --- RK NQMKST P WIK AYE RNNVLS - 492
Cdd:pfam01274 235 RG T IRATVLI E TLPA S FQMDEI I YEL R DHS A GL N C G RW D YIFSYIKTLRN A PD M V lpd RK AVTMTA P FMR AYE KLLIKT c 314
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446006257 493 ----- GLFC G LRGKAQ I GKG M W A MPDL M ADMYSQ K GDQL RAG ANTA WV PS P TA A T L H A LHY HQ TN V QSV Q ANI A QT E FNA 567
Cdd:pfam01274 315 hkrgv HAMG G MAAQIP I KDD M E A NTAA M EKVRAD K LREV RAG HDGT WV AH P GL A P L A A EVF HQ VM V RPN Q IEL A RE E DSI 394
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446006257 568 E fepl L DDLLTIP VA enanwsv EE IQQE L D NN V Q GI L G YV VR W V e Q G I GC sk VP D IH nva LMED R AT LR IS S Q HIAN WLR 647
Cdd:pfam01274 395 T ---- A DDLLTIP DG ------- EE TEEG L R NN I Q VG L Q YV EA W L - R G S GC -- VP I IH --- LMED A AT AE IS R Q QLWQ WLR 457
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 446006257 648 HG ILTK E Q V QAS LE N MAK V VD QQ NA ------- GD P AYR PM --------- A GNFANSSAFK A AS DLI 697
Cdd:pfam01274 458 HG VTLD E G V RVT LE L MAK L VD EE NA rlakerf GD G AYR DA arlflqqat A EEYDDFLTLL A YD DLI 523
malate_synt
cd00480 Malate synthase catalyzes the Claisen condensation of glyoxylate and acetyl-CoA to malyl-CoA , ...
35-716
0e+00
Malate synthase catalyzes the Claisen condensation of glyoxylate and acetyl-CoA to malyl-CoA , which hydrolyzes to malate and CoA. This reaction is part of the glyoxylate cycle, which allows certain organisms, like plants and fungi, to derive their carbon requirements from two-carbon compounds, by bypassing the two carboxylation steps of the citric acid cycle.
Pssm-ID: 238267
Cd Length: 511
Bit Score: 553.38
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446006257 35 FWRNFDQIVHDLA P EN R Q LLA E RD RI QA A LD EW H rsnpgpvkdka A YKS FL R E LG Y L v PQPERVT V ETT -- GI D SEITSQ 112
Cdd:cd00480 1 ALAFVAELHREFN P RR R E LLA A RD ER QA R LD AG H ----------- A LPD FL P E TA Y I - RRDGDWK V APD pp DL D DRRVEI 68
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446006257 113 A GPQ LVVPAM NA RYALN A anarwgslydalygsdiipqegamvsgydpqrgeqviawvrrfldeslplkngsyqdvvafk 192
Cdd:cd00480 69 T GPQ DRKMVI NA LNSGA A -------------------------------------------------------------- 86
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446006257 193 vvdkqlriqlkngkettlrtpaqfvgyrgdsaaptcillknnglhielqidangrigkddpahindviveaai STIL D C E 272
Cdd:cd00480 87 ------------------------------------------------------------------------- VFMA D F E 93
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446006257 273 DS V A AV d A E D K ILLY RNLL GLMQ GT LQEKME KNG RQIVRK L nddrqytaadgseis L H GR SL LF I R NV G HLM T IPV I WDS 352
Cdd:cd00480 94 DS S A PT - W E N K VEGQ RNLL DAVR GT ISFTDS KNG KSYRLN L --------------- L D GR AT LF V R PR G WHL T EKH I LVD 157
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446006257 353 e G NEI P E G IL D GVMTGAIALYD LK vqkn S R TGSV Y IVK PKM HG P Q E VAFA N KL F T R I E TM LG MAPN T L K MGIMD E ERRTS 432
Cdd:cd00480 158 - G EPV P G G LF D FGLYFFHNAHA LK ---- A R GSGP Y FYL PKM ES P L E ARLW N DV F S R A E DY LG LPRG T I K ATVLI E TLPAA 232
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446006257 433 LNLRSCIAQA R NRV A FI N T G FL D RTGD E MHSVM ---- EAG P MLR K NQ M k ST P WIK AYE RNN V LSGLFC G L ---- RGK AQI 504
Cdd:cd00480 233 FEMDEILYEL R DHS A GL N C G RW D YIFS E IKTFR nhpd FVL P DRA K VT M - TS P FMR AYE KLL V KTCHRR G A hamg GMA AQI 311
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446006257 505 G - KG MW A MPD - L MA DMYSQ K GDQLR AG ANTA WV PS P TA A T L H AL HY H QTNVQSV Q ANIAQTEFNA efep LL DDLLTIPVA 582
Cdd:cd00480 312 P i KG DP A ANE a A MA KVRAD K LREAK AG HDGT WV AH P GL A P L A AL VF H KVMPGPN Q LFRKREDVKV ---- TA DDLLTIPVA 387
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446006257 583 E N anwsv EEIQQE L D NN V Q GI LGYVV R W VE qgi G CSK VP D I H nva LMED R AT LR IS SQHIAN WLRHG ILTKEQ V QAS LE N 662
Cdd:cd00480 388 E G ----- DITEEG L R NN I Q VA LGYVV A W LN --- G NGA VP I I N --- LMED A AT AE IS RSQLWQ WLRHG VCLDDG V PVT LE L 456
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|....*..
gi 446006257 663 M AK V VD QQ NA GD PAYRP ma G NF AN S S AFK A A S DL I F L GV --- KQ P NGY TEPL L H AW R 716
Cdd:cd00480 457 V AK L VD EE NA RL PAYRP -- P NF FD S I AFK E A A DL F F E GV tae EF P EFL TEPL Y H LL R 511
PRK08951
PRK08951 malate synthase; Provisional
173-335
1.70e-30
malate synthase; Provisional
Pssm-ID: 181593 [Multi-domain]
Cd Length: 190
Bit Score: 118.59
E-value: 1.70e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446006257 173 FLD ESL PL K NGS Y QDV VAF k VV D - KQ L RIQLKN G KETT LR T P A QFV GYR G DSAA P TC ILLK NN G L H I EL QI D AN G RI G KD 251
Cdd:PRK08951 44 FLD RLF PL A NGS H QDV SSY - VV Y y QH L LAFFAD G SHSG LR Q P K QFV AFN G HKSE P SA ILLK DS G S H V EL TF D RH G GT G SR 122
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446006257 252 D P A H I N D VIV E AAISTILDCEDSVAAV daedkill Y R NLLG L MQ G TLQEKMEKNGR qivrklnd D RQY TA A DGS EIS L HG 331
Cdd:PRK08951 123 D L A N I E D IQL E TCTTFSQEPTENRSTA -------- M R HWIS L LK G DESGRPAADQE -------- D KEF TA K DGS DYQ L KS 186
....
gi 446006257 332 RSL L 335
Cdd:PRK08951 187 CFS L 190
malate_synt_A
cd00727 Malate synthase A (MSA), present in some bacteria, plants and fungi. Prokaryotic MSAs tend to ...
318-670
1.93e-11
Malate synthase A (MSA), present in some bacteria, plants and fungi. Prokaryotic MSAs tend to be monomeric, whereas eukaryotic enzymes are homomultimers. In general, malate synthase catalyzes the Claisen condensation of glyoxylate and acetyl-CoA to malyl-CoA, which hydrolyzes to malate and CoA. This reaction is part of the glyoxylate cycle, which allows certain organisms, like plants and fungi, to derive their carbon requirements from two-carbon compounds, by bypassing the two carboxylation steps of the citric acid cycle.
Pssm-ID: 238369
Cd Length: 511
Bit Score: 66.89
E-value: 1.93e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446006257 318 QY T AAD G S E IS L HGR - SL L FI R NV G - HL MTIP V IW D se G NEIPEGIL D gvmtga IA LY --- DL K VQKNSRT G s V Y IVK PK 392
Cdd:cd00727 122 SF T SPE G K E YK L NDT p AT L IV R PR G w HL PEKH V LV D -- G EPVSGSLF D ------ FG LY ffh NA K ALLARGS G - P Y FYL PK 192
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446006257 393 M HGPQ E VAFA N KL F TRIETM LG MAPN T L K MGI ---------- MDE ------ ERRTS LN ------ LR S C I AQA RN RVA F I n 450
Cdd:cd00727 193 M ESHL E ARLW N DV F VFAQDY LG LPRG T I K ATV lietlpaafe MDE ilyelr DHSAG LN cgrwdy IF S F I KKF RN HPD F V - 271
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446006257 451 tg FL DR TG demh SV M EA gpmlrknqmkst P WIK AY ERNNVLS glf C GL RG KAQI G k GM W A M ------ P DL ---- M A DMYS 520
Cdd:cd00727 272 -- LP DR AQ ---- VT M TV ------------ P FMR AY SELLIKT --- C HR RG AHAM G - GM A A Q ipikdd P AA neaa L A KVRA 329
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446006257 521 Q K GDQLR AG ANTA WV PS P TAA ------- TL H ALHYH Q TN V QSVQANIAQ tefnaefepll D DLL TI PV AE nanwsve E I Q 593
Cdd:cd00727 330 D K LREAT AG HDGT WV AH P GLV pvamevf DK H MPGPN Q LD V LREDVKVTA ----------- A DLL LV PV EG ------- G I T 391
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 446006257 594 Q E - L DN N VQGI L G Y VVR W V e Q G I GC sk VP d I H N va LMED R AT LR IS SQHIAN W L RHG iltkeqvq AS L ENMAKV V DQQ 670
Cdd:cd00727 392 E E g L RQ N ISVG L Q Y LAA W L - R G N GC -- VP - I Y N -- LMED A AT AE IS RAQLWQ W I RHG -------- VR L LDDGRP V TAE 455
PLN02626
PLN02626 malate synthase
391-670
1.74e-08
malate synthase
Pssm-ID: 215336
Cd Length: 551
Bit Score: 57.86
E-value: 1.74e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446006257 391 PKM HGPQ E VAFA N KL F TRI E T M L G MAPNTLKMGIMD E ERRTSLNLRSCIAQA R NRV A FI N T G FL D R -------------- 456
Cdd:PLN02626 218 PKM EHSR E ARLW N DV F EAA E K M A G IPRGSIRATVLI E TLPAVFQMEEILYEL R DHS A GL N C G RW D Y ifsfvktfrahpdr 297
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446006257 457 - TG D EMHSV M eagpmlrknqmk STPWI K A Y ERNNVLS glf C GL RG KAQI G k GM W A MPDLMA D ------- MYSQKG D Q LR - 527
Cdd:PLN02626 298 l LP D RVQVG M ------------ TQHFM K S Y VDLLIKT --- C HK RG VHAM G - GM A A QIPIKD D paaneaa LALVRK D K LR e 361
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446006257 528 -- AG ANTA W VPS P -- TAATLHALHY H QTNVQSV Q ANIAQTEF N AEFE plld DLL TI P VAE nanwsve EIQQE L DN N VQGI 603
Cdd:PLN02626 362 vr AG HDGT W AAH P gl IPLAMEVFDG H MPTPNNQ Q LHKRRDDV N VTEA ---- DLL QV P RGV ------- RTLEG L RL N TRVG 430
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446006257 604 LG Y VVR W V e Q G I G C sk VP d IH N va LMED R AT LR IS SQHIAN W LRH G ILTKE --- Q V QASL E NMAK VV DQQ 670
Cdd:PLN02626 431 IQ Y LAA W L - T G T G S -- VP - LY N -- LMED A AT AE IS RVQNWQ W IKY G AELDG dgv G V RVTA E LFGR VV EEE 494
AceB
COG2225 Malate synthase [Energy production and conversion]; Malate synthase is part of the Pathway ...
574-697
4.43e-05
Malate synthase [Energy production and conversion]; Malate synthase is part of the Pathway/BioSystem: TCA cycle, glyoxylate bypass
Pssm-ID: 441827
Cd Length: 530
Bit Score: 46.64
E-value: 4.43e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 446006257 574 D DLL TI P VAE nanws VE E iq QE L D NN VQGILG Y VVR W V e Q G I G C sk VP d I H N va LMED R AT LR IS - SQ h IAN W LR HG --- 649
Cdd:COG2225 400 A DLL DV P EGT ----- IT E -- AG L R NN ISVGIQ Y LEA W L - R G N G A -- VP - I Y N -- LMED A AT AE IS r SQ - VWQ W IH HG atl 465
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|...
gi 446006257 650 ---- IL T K E Q V QAS L - E NM AK V vd QQNA G DPAY rpmagnfa NSSA F KA A SD L I 697
Cdd:COG2225 466 ddgr KV T A E L V RQL L a E EL AK L -- RAEV G EERF -------- EAGR F DE A AE L F 508
Blast search parameters
Data Source:
Precalculated data, version = cdd.v.3.21
Preset Options: Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
