|
Name |
Accession |
Description |
Interval |
E-value |
| PRK05101 |
PRK05101 |
galactokinase; Provisional |
1-382 |
0e+00 |
|
galactokinase; Provisional
Pssm-ID: 179937 [Multi-domain] Cd Length: 382 Bit Score: 819.94 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445975554 1 MSLKEKTQSLFANAFGYPATHTIQAPGRVNLIGEHTDYNDGFVLPCAIDYQTVISCAPRDDRKVRVMAADYENQLDEFSL 80
Cdd:PRK05101 1 MSLKQKTQSLFAQQFGYPPTHTIQAPGRVNLIGEHTDYNDGFVLPCAIDYQTVISCAKRDDRIVRVIAADYDNQQDEFSL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445975554 81 DAPIVAHENYQWANYVRGVVKHLQLRNNNFGGVDMVISGNVPQGAGLSSSASLEVAVGTVLQQLYHLPLDGAQIALNGQE 160
Cdd:PRK05101 81 DAPIVPHPEQQWANYVRGVVKHLQERNPDFGGADLVISGNVPQGAGLSSSASLEVAVGQTFQQLYHLPLSGAEIALNGQE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445975554 161 AENQFVGCNCGIMDQLISALGKKDHALLIDCRSLGTKAVSMPKGVAVVIINSNFKRTLVGSEYNTRREQCETGARFFQQP 240
Cdd:PRK05101 161 AENQFVGCNCGIMDQLISALGKKDHALLIDCRSLETKAVPMPEGVAVVIINSNVKRGLVDSEYNTRRQQCETAARFFGVK 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445975554 241 ALRDVTIEEFNAVAHELDPIVAKRVRHILTENARTVEAASALEQGDLKRMGELMAESHASMRDDFEITVPQIDTLVEIVK 320
Cdd:PRK05101 241 ALRDVTLEQFNAVAAELDPVVAKRARHVITENARTLEAASALAAGDLKRMGELMAESHASMRDDFEITVPQIDTLVEIVK 320
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 445975554 321 AVIGDKGGVRMTGGGFGGCIVALLPEELVPAVQQAVAEQYEAKTGIKETFYVCKPSQGAGQC 382
Cdd:PRK05101 321 AVIGDQGGVRMTGGGFGGCIVALVPEELVEAVRQAVAEQYEAKTGLKETFYVCKASQGAGQC 382
|
|
| gal_kin |
TIGR00131 |
galactokinase; Galactokinase is a member of the GHMP kinases (Galactokinase, Homoserine kinase, ... |
4-382 |
0e+00 |
|
galactokinase; Galactokinase is a member of the GHMP kinases (Galactokinase, Homoserine kinase, Mevalonate kinase, Phosphomevalonate kinase) and shares with them an amino-terminal domain probably related to ATP binding.The galactokinases found by this model are divided into two sets. Prokaryotic forms are generally shorter. The eukaryotic forms are longer because of additional central regions and in some cases are known to be bifunctional, with regulatory activities that are independent of galactokinase activity. [Energy metabolism, Sugars]
Pssm-ID: 272924 [Multi-domain] Cd Length: 386 Bit Score: 637.64 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445975554 4 KEKTQSLFANAFGYPATHTIQAPGRVNLIGEHTDYNDGFVLPCAIDYQTVISCAPRDDRKVRVMAADYENQLDEFSLDAP 83
Cdd:TIGR00131 1 CESIQKIFASAFGAKPDFTARAPGRVNLIGEHTDYNDGSVLPCAIDFGTLCAVAVRDDKNVRIYLANADNKFAERSLDLP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445975554 84 IVAHENYQWANYVRGVVKHLQLRNNNFG-GVDMVISGNVPQGAGLSSSASLEVAVGTVLQQLYHLPLDGAQIALNGQEAE 162
Cdd:TIGR00131 81 LDGSEVSDWANYFKGVLHVAQERFNSFPlGADIVCSGNVPTGSGLSSSAAFECAVGAVLQNMGHLPLDSKQILLRIQVAE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445975554 163 NQFVGCNCGIMDQLISALGKKDHALLIDCRSLGTKAVSMPK-GVAVVIINSNFKRTLVGSEYNTRREQCETGARFFQQP- 240
Cdd:TIGR00131 161 NHFVGVNCGIMDQAASVLGKEDHALLVECRSLKATPFKFPQlGIAFVIANTNVKRTLAPSNYNTRRQECTTAANFLAATd 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445975554 241 --ALRDVTIEEFN---AVAHELDPIVAKRVRHILTENARTVEAASALEQGDLKRMGELMAESHASMRDDFEITVPQIDTL 315
Cdd:TIGR00131 241 kgALRDFMNEYFAryiARLTKMLPLVEERAKHVVSENLRVLKAVKAMKDNDFKQFGALMNESHASCDDDYECTCPEIDEL 320
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 445975554 316 VEIVKAVIGdKGGVRMTGGGFGGCIVALLPEELVPAVQQAVAEQYEAKTGIKETFYVCKPSQGAGQC 382
Cdd:TIGR00131 321 VCSAALVNG-SGGSRMTGAGFGGCTVHLVPNENVDKVRQAVADKYPKKTGLELTFYVIVSKPGAGSC 386
|
|
| GalK |
COG0153 |
Galactokinase [Carbohydrate transport and metabolism]; |
3-382 |
0e+00 |
|
Galactokinase [Carbohydrate transport and metabolism];
Pssm-ID: 439923 [Multi-domain] Cd Length: 380 Bit Score: 591.75 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445975554 3 LKEKTQSLFANAFGYPATHTIQAPGRVNLIGEHTDYNDGFVLPCAIDYQTVISCAPRDDRKVRVMAADYENQlDEFSLDa 82
Cdd:COG0153 1 RLERLIEAFEEAFGEEPEGVFSAPGRVNLIGEHTDYNGGFVLPAAIDRGTYAAARPRDDRKVRVYSADFDEE-VEFDLD- 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445975554 83 PIVAHENYQWANYVRGVVKHLQLRNNNFGGVDMVISGNVPQGAGLSSSASLEVAVGTVLQQLYHLPLDGAQIALNGQEAE 162
Cdd:COG0153 79 DLEPGEEDGWANYVRGVAWALQERGYKLGGFDLVIDGDVPLGAGLSSSAALEVAVALALNDLFGLGLDPVELAKIGQRAE 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445975554 163 NQFVGCNCGIMDQLISALGKKDHALLIDCRSLGTKAVSMP-KGVAVVIINSNFKRTLVGSEYNTRREQCETGARFFQQPA 241
Cdd:COG0153 159 NEFVGVPCGIMDQFASALGKKGHALLLDCRSLEYEYVPLPlEGYALVIVDTNVKHSLADSEYNERRAECEAAAAILGVKS 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445975554 242 LRDVTIEEFNAVAHEL-DPIVAKRVRHILTENARTVEAASALEQGDLKRMGELMAESHASMRDDFEITVPQIDTLVEIVK 320
Cdd:COG0153 239 LRDVTLEDLEAARARLgDEVLRRRARHVVTENQRVLEAVEALRAGDLEAFGKLMNASHASLRDDYEVSCPELDTLVELAL 318
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 445975554 321 AVIGDkGGVRMTGGGFGGCIVALLPEELVPAVQQAVAEQYEAKTGIKETFYVCKPSQGAGQC 382
Cdd:COG0153 319 AEAGV-LGARMTGGGFGGCTIALVPKDAVDEFIEAVAEAYAEKTGLEPDFYVVKPSDGARRL 379
|
|
| GalKase_gal_bdg |
pfam10509 |
Galactokinase galactose-binding signature; This is the highly conserved galactokinase ... |
9-58 |
3.36e-21 |
|
Galactokinase galactose-binding signature; This is the highly conserved galactokinase signature sequence which appears to be present in all galactokinases irrespective of how many other ATP binding sites, etc that they carry. The function of this domain appears to be to bind galactose, and the domain is normally at the N-terminus of the enzymes, EC:2.7.1.6. This domain is associated with the families GHMP_kinases_C, pfam08544 and GHMP_kinases_N, pfam00288.
Pssm-ID: 463125 [Multi-domain] Cd Length: 50 Bit Score: 85.58 E-value: 3.36e-21
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 445975554 9 SLFANAFGYPATHTIQAPGRVNLIGEHTDYNDGFVLPCAIDYQTVISCAP 58
Cdd:pfam10509 1 EAFEELFGKEPVGVASAPGRVNLIGEHTDYNGGFVLPAAINLDTYVAVSP 50
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK05101 |
PRK05101 |
galactokinase; Provisional |
1-382 |
0e+00 |
|
galactokinase; Provisional
Pssm-ID: 179937 [Multi-domain] Cd Length: 382 Bit Score: 819.94 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445975554 1 MSLKEKTQSLFANAFGYPATHTIQAPGRVNLIGEHTDYNDGFVLPCAIDYQTVISCAPRDDRKVRVMAADYENQLDEFSL 80
Cdd:PRK05101 1 MSLKQKTQSLFAQQFGYPPTHTIQAPGRVNLIGEHTDYNDGFVLPCAIDYQTVISCAKRDDRIVRVIAADYDNQQDEFSL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445975554 81 DAPIVAHENYQWANYVRGVVKHLQLRNNNFGGVDMVISGNVPQGAGLSSSASLEVAVGTVLQQLYHLPLDGAQIALNGQE 160
Cdd:PRK05101 81 DAPIVPHPEQQWANYVRGVVKHLQERNPDFGGADLVISGNVPQGAGLSSSASLEVAVGQTFQQLYHLPLSGAEIALNGQE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445975554 161 AENQFVGCNCGIMDQLISALGKKDHALLIDCRSLGTKAVSMPKGVAVVIINSNFKRTLVGSEYNTRREQCETGARFFQQP 240
Cdd:PRK05101 161 AENQFVGCNCGIMDQLISALGKKDHALLIDCRSLETKAVPMPEGVAVVIINSNVKRGLVDSEYNTRRQQCETAARFFGVK 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445975554 241 ALRDVTIEEFNAVAHELDPIVAKRVRHILTENARTVEAASALEQGDLKRMGELMAESHASMRDDFEITVPQIDTLVEIVK 320
Cdd:PRK05101 241 ALRDVTLEQFNAVAAELDPVVAKRARHVITENARTLEAASALAAGDLKRMGELMAESHASMRDDFEITVPQIDTLVEIVK 320
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 445975554 321 AVIGDKGGVRMTGGGFGGCIVALLPEELVPAVQQAVAEQYEAKTGIKETFYVCKPSQGAGQC 382
Cdd:PRK05101 321 AVIGDQGGVRMTGGGFGGCIVALVPEELVEAVRQAVAEQYEAKTGLKETFYVCKASQGAGQC 382
|
|
| gal_kin |
TIGR00131 |
galactokinase; Galactokinase is a member of the GHMP kinases (Galactokinase, Homoserine kinase, ... |
4-382 |
0e+00 |
|
galactokinase; Galactokinase is a member of the GHMP kinases (Galactokinase, Homoserine kinase, Mevalonate kinase, Phosphomevalonate kinase) and shares with them an amino-terminal domain probably related to ATP binding.The galactokinases found by this model are divided into two sets. Prokaryotic forms are generally shorter. The eukaryotic forms are longer because of additional central regions and in some cases are known to be bifunctional, with regulatory activities that are independent of galactokinase activity. [Energy metabolism, Sugars]
Pssm-ID: 272924 [Multi-domain] Cd Length: 386 Bit Score: 637.64 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445975554 4 KEKTQSLFANAFGYPATHTIQAPGRVNLIGEHTDYNDGFVLPCAIDYQTVISCAPRDDRKVRVMAADYENQLDEFSLDAP 83
Cdd:TIGR00131 1 CESIQKIFASAFGAKPDFTARAPGRVNLIGEHTDYNDGSVLPCAIDFGTLCAVAVRDDKNVRIYLANADNKFAERSLDLP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445975554 84 IVAHENYQWANYVRGVVKHLQLRNNNFG-GVDMVISGNVPQGAGLSSSASLEVAVGTVLQQLYHLPLDGAQIALNGQEAE 162
Cdd:TIGR00131 81 LDGSEVSDWANYFKGVLHVAQERFNSFPlGADIVCSGNVPTGSGLSSSAAFECAVGAVLQNMGHLPLDSKQILLRIQVAE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445975554 163 NQFVGCNCGIMDQLISALGKKDHALLIDCRSLGTKAVSMPK-GVAVVIINSNFKRTLVGSEYNTRREQCETGARFFQQP- 240
Cdd:TIGR00131 161 NHFVGVNCGIMDQAASVLGKEDHALLVECRSLKATPFKFPQlGIAFVIANTNVKRTLAPSNYNTRRQECTTAANFLAATd 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445975554 241 --ALRDVTIEEFN---AVAHELDPIVAKRVRHILTENARTVEAASALEQGDLKRMGELMAESHASMRDDFEITVPQIDTL 315
Cdd:TIGR00131 241 kgALRDFMNEYFAryiARLTKMLPLVEERAKHVVSENLRVLKAVKAMKDNDFKQFGALMNESHASCDDDYECTCPEIDEL 320
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 445975554 316 VEIVKAVIGdKGGVRMTGGGFGGCIVALLPEELVPAVQQAVAEQYEAKTGIKETFYVCKPSQGAGQC 382
Cdd:TIGR00131 321 VCSAALVNG-SGGSRMTGAGFGGCTVHLVPNENVDKVRQAVADKYPKKTGLELTFYVIVSKPGAGSC 386
|
|
| GalK |
COG0153 |
Galactokinase [Carbohydrate transport and metabolism]; |
3-382 |
0e+00 |
|
Galactokinase [Carbohydrate transport and metabolism];
Pssm-ID: 439923 [Multi-domain] Cd Length: 380 Bit Score: 591.75 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445975554 3 LKEKTQSLFANAFGYPATHTIQAPGRVNLIGEHTDYNDGFVLPCAIDYQTVISCAPRDDRKVRVMAADYENQlDEFSLDa 82
Cdd:COG0153 1 RLERLIEAFEEAFGEEPEGVFSAPGRVNLIGEHTDYNGGFVLPAAIDRGTYAAARPRDDRKVRVYSADFDEE-VEFDLD- 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445975554 83 PIVAHENYQWANYVRGVVKHLQLRNNNFGGVDMVISGNVPQGAGLSSSASLEVAVGTVLQQLYHLPLDGAQIALNGQEAE 162
Cdd:COG0153 79 DLEPGEEDGWANYVRGVAWALQERGYKLGGFDLVIDGDVPLGAGLSSSAALEVAVALALNDLFGLGLDPVELAKIGQRAE 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445975554 163 NQFVGCNCGIMDQLISALGKKDHALLIDCRSLGTKAVSMP-KGVAVVIINSNFKRTLVGSEYNTRREQCETGARFFQQPA 241
Cdd:COG0153 159 NEFVGVPCGIMDQFASALGKKGHALLLDCRSLEYEYVPLPlEGYALVIVDTNVKHSLADSEYNERRAECEAAAAILGVKS 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445975554 242 LRDVTIEEFNAVAHEL-DPIVAKRVRHILTENARTVEAASALEQGDLKRMGELMAESHASMRDDFEITVPQIDTLVEIVK 320
Cdd:COG0153 239 LRDVTLEDLEAARARLgDEVLRRRARHVVTENQRVLEAVEALRAGDLEAFGKLMNASHASLRDDYEVSCPELDTLVELAL 318
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 445975554 321 AVIGDkGGVRMTGGGFGGCIVALLPEELVPAVQQAVAEQYEAKTGIKETFYVCKPSQGAGQC 382
Cdd:COG0153 319 AEAGV-LGARMTGGGFGGCTIALVPKDAVDEFIEAVAEAYAEKTGLEPDFYVVKPSDGARRL 379
|
|
| PRK05322 |
PRK05322 |
galactokinase; Provisional |
2-379 |
3.32e-138 |
|
galactokinase; Provisional
Pssm-ID: 235407 [Multi-domain] Cd Length: 387 Bit Score: 398.85 E-value: 3.32e-138
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445975554 2 SLKEKtqslFANAFGYPATHTIQAPGRVNLIGEHTDYNDGFVLPCAIDYQTVISCAPRDDRKVRVMAADYENQLD-EFSL 80
Cdd:PRK05322 5 ELKKK----FAEVFGEEAEDVFFSPGRINLIGEHTDYNGGHVFPAAITLGTYGAARKRDDKKVRLYSANFEDLGIiEFDL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445975554 81 DApIVAHENYQWANYVRGVVKHLQLRNNNF-GGVDMVISGNVPQGAGLSSSASLEVAVGTVLQQLYHLPLDGAQIALNGQ 159
Cdd:PRK05322 81 DD-LSFDKEDDWANYPKGVLKFLQEAGYKIdHGFDILIYGNIPNGAGLSSSASIELLTGVILKDLFNLDLDRLELVKLGQ 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445975554 160 EAENQFVGCNCGIMDQLISALGKKDHALLIDCRSLGTKAVsmP---KGVAVVIINSNFKRTLVGSEYNTRREQCETGARF 236
Cdd:PRK05322 160 KTENEFIGVNSGIMDQFAIGMGKKDHAILLDCNTLEYEYV--PldlGDYVIVIMNTNKRRELADSKYNERRAECEKALEE 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445975554 237 FQQ----PALRDVTIEEFNAVAHEL-DPIVAKRVRHILTENARTVEAASALEQGDLKRMGELMAESHASMRDDFEITVPQ 311
Cdd:PRK05322 238 LQKkldiKSLGELTEEEFDEYSYLIkDETLLKRARHAVTENQRTLKAVKALKAGDLEKFGRLMNASHVSLRDDYEVTGLE 317
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 445975554 312 IDTLVEI---VKAVIgdkgGVRMTGGGFGGCIVALLPEELVPAVQQAVAEQYEAKTGIKETFYVCKPSQGA 379
Cdd:PRK05322 318 LDTLVEAawkQEGVL----GARMTGAGFGGCAIAIVKKDKVEAFKENVGKAYEEKIGYAASFYVAEIGDGA 384
|
|
| PRK03817 |
PRK03817 |
galactokinase; Provisional |
22-382 |
2.06e-114 |
|
galactokinase; Provisional
Pssm-ID: 235163 [Multi-domain] Cd Length: 351 Bit Score: 337.35 E-value: 2.06e-114
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445975554 22 TIQAPGRVNLIGEHTDYNDGFVLPCAIDYQTVISCAPrdDRKVRVMAaDYENQLDEFSLDApiVAHENyQWANYVRGVVK 101
Cdd:PRK03817 2 KVKSPGRVNLIGEHTDYNDGYVLPFAINLYTFLEIEK--SEKFIFYS-ENFNEEKTFELDK--LEKLN-SWADYIKGVIW 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445975554 102 HLQLRNNNFGGVDMVISGNVPQGAGLSSSASLEVAVGTVLQQLYHLPLDGAQIALNGQEAENQFVGCNCGIMDQLISALG 181
Cdd:PRK03817 76 VLEKRGYEVGGVKGKVSSNLPIGAGLSSSASLEVAVAYALNEAYNLNLSKLELALLAREAENEFVGVPCGIMDQFAVAFG 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445975554 182 KKDHALLIDCRSLGTKAVSMPKGVAVVIINSNFKRTLVGSEYNTRREQCETGARFFQQPALRDVTIEEFnavaHELDPIV 261
Cdd:PRK03817 156 KKDHAIFLDTMTLEYEYVPFPEDYEILVFDTGVKRELASSEYNERRQECEEALKILGKKSSKEVTEEDL----SKLPPLL 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445975554 262 AKRVRHILTENARTVEAASALEQGDLKRMGELMAESHASMRDDFEITVPQIDTLVEIVKavigDKG--GVRMTGGGFGGC 339
Cdd:PRK03817 232 RKRAGYVLRENERVLKVRDALKEGDIETLGELLTESHWDLADNYEVSCEELDFFVEFAL----ELGayGARLTGAGFGGS 307
|
330 340 350 360
....*....|....*....|....*....|....*....|...
gi 445975554 340 IVALLPEELVPAVQQAVAEQYEAKTGIKETFYVCKPSQGAGQC 382
Cdd:PRK03817 308 AIALVDKGKFESIGEELLEEYKKRFGIDPKYFVVESSDGVRKI 350
|
|
| PRK00555 |
PRK00555 |
galactokinase; Provisional |
25-382 |
9.23e-92 |
|
galactokinase; Provisional
Pssm-ID: 179063 [Multi-domain] Cd Length: 363 Bit Score: 279.82 E-value: 9.23e-92
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445975554 25 APGRVNLIGEHTDYNDGFVLPCAIDYQTVISCAPRDDRKVRVmAADYENQLDEFSLDApiVAHENYQWANYVRGVVKHLQ 104
Cdd:PRK00555 7 APGRINLIGEHTDYNLGFALPIALPQRTVVTFTPEHTDAITA-SSDRADGSARIPLDT--TPGQVTGWAAYAAGVIWALR 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445975554 105 LRNNNFGGVDMVISGNVPQGAGLSSSASLEVAVGTVLQQLYHLPLDGAQIALNGQEAENQFVGCNCGIMDQLISALGKKD 184
Cdd:PRK00555 84 GAGHPVPGGAMSITSDVEIGSGLSSSAALECAVLGAVGAATGTRIDRLEQARLAQRAENEYVGAPTGLLDQLAALFGAPK 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445975554 185 HALLIDCRSLGTKAVSM---PKGVAVVIINSNFKRTLVGSEYNTRREQCETGARFFQQPALRDVTIEEFNAVAHELDPIV 261
Cdd:PRK00555 164 TALLIDFRDLTVRPVAFdpdAAGVVLLLMDSRARHRHAGGEYAARRASCERAAADLGVSSLRAVQDRGLAALGAIADPID 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445975554 262 AKRVRHILTENARTVEAASALEQGDLKRMGELMAESHASMRDDFEITVPQIDTLVEivKAVIGDKGGVRMTGGGFGGCIV 341
Cdd:PRK00555 244 ARRARHVLTENQRVLDFAAALADSDFTAAGQLLTASHASMRDDFEITTERIDLIAD--SAVRAGALGARMTGGGFGGCVI 321
|
330 340 350 360
....*....|....*....|....*....|....*....|.
gi 445975554 342 ALLPEELVPAVQQAVAEQYEAKTGIKETFYVCKPSQGAGQC 382
Cdd:PRK00555 322 ALVPADRAEDVADTVRRAAVTAGYPEPAVSRTYAAPGAGEC 362
|
|
| PLN02521 |
PLN02521 |
galactokinase |
11-379 |
1.16e-52 |
|
galactokinase
Pssm-ID: 215285 [Multi-domain] Cd Length: 497 Bit Score: 182.21 E-value: 1.16e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445975554 11 FANAFGYPATHTIQAPGRVNLIGEHTDYNDGFVLPCAIDYQTVISCAPRD-DRKVRVMAADYENQLDEFSLD-APIVAHE 88
Cdd:PLN02521 39 FVEVYGAKPDLFARSPGRVNLIGEHIDYEGYSVLPMAIRQDTIVAIRRAEgSKKLRIANVNDKYTTCTFPADpDQEVDLA 118
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445975554 89 NYQWANYV----RGVVKHLQLRNNNFG---GVDMVISGNVPQGAGLSSSASLEVAVGTVLQQLYHLPLDGAQIALNGQEA 161
Cdd:PLN02521 119 NHKWGNYFicgyKGVFEFLKSKGVDVGppvGLDVVVDGTVPTGSGLSSSAALVCSAAIAIMAALGLNFTKKEVAQFTCKC 198
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445975554 162 EnQFVGCNCGIMDQLISALGKKDHALLIDCRSLGTKAVSMPKGVAVVIINS---NFKRTLVGSEYNTRREQCETGARFF- 237
Cdd:PLN02521 199 E-RHIGTQSGGMDQAISIMAQQGVAKLIDFNPVRATDVQLPAGGTFVIANSlaeSNKAVTAATNYNNRVVECRLAAIVLa 277
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445975554 238 ------QQPA------LRDV-----------------------------TIEEFNAV-AHELDPIVA------------- 262
Cdd:PLN02521 278 vklgmsAEEAiskvktLSDVeglcvsfagshgssdpavavkellhegpyTAEEIEEIlGESLTSIFKnsptslavlkaak 357
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445975554 263 -----KRVRHILTENAR-----TVEAASALEQGDLKRMGELMAESHASMRDDFEITVPQIDTLVEIVKAviGDKGGVRMT 332
Cdd:PLN02521 358 hfklhQRAVHVYSEAKRvhafrDTVSSSLSEEEKLKKLGDLMNESHYSCSVLYECSCPELEELVKVCRD--NGALGARLT 435
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*.
gi 445975554 333 GGGFGGCIVALLPEELVPAVQQAVAEQYE---------AKTGIKETFYVCKPSQGA 379
Cdd:PLN02521 436 GAGWGGCAVALVKEAIVPQFILALKEKFYksriekgviKEEDLGLYVFASKPSSGA 491
|
|
| PTZ00290 |
PTZ00290 |
galactokinase; Provisional |
25-379 |
5.75e-46 |
|
galactokinase; Provisional
Pssm-ID: 240347 [Multi-domain] Cd Length: 468 Bit Score: 163.84 E-value: 5.75e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445975554 25 APGRVNLIGEHTDYNDGFVLPCAIDYQTVI---SCAPRDDRKVRVMAADYENqldeFSLDAPIVAHENYQWANYVRGVVk 101
Cdd:PTZ00290 42 APGRVNFIGEHVDYMGGYVCPAAVLEGCHIlvgRVKHFCDHKLRFATETDEH----FVLDHLGGAKHNKAWTTFVRGAA- 116
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445975554 102 hlQLRNNNFG---------GVDMVISGNVPQGAGLSSSASLEV----AVGTVLQQLYH------------LPLDGAQ--- 153
Cdd:PTZ00290 117 --TLRLNRLGvaidapslqGVCMVVHGTLPMGAGMSASASFGVallnAINTVVTRRYKgcptspgrrysiLPPMSKEeli 194
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445975554 154 -IALNGQEAENQFVGCNCGIMDQLISALGKKDHALLIDCRSLGTKAVSMP----KGVAVVIINSNFKRTLVGSE---YNT 225
Cdd:PTZ00290 195 eLAKQARRIETEFCGVNVGIMDQFISAFAEEDKFMFLDCKSLTFESHDMTpllgDGACFLLIDSMIKHDLLGGTagmYNT 274
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445975554 226 RREQCETGARFFQQPALR--------------------DVT--IEEFNAvahELDPIVAKRVRHILTENARTVE------ 277
Cdd:PTZ00290 275 VRSDQEGAQKKIGKHRYRgkpftfsdlvrnpkkytfdgDVVafMESCKP---LMTPGEFERGTYNIMEQIRTLEfiklnd 351
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445975554 278 AASALEQGD-LKRMGELMAESHASMRDDFEITVPQIDTLVEIVKAVIGDKGGvRMTGGGFGGCIVALLPEELVPAVQQAV 356
Cdd:PTZ00290 352 PELPLSREErFRKAGEILNAGHQGMRDLMKITTPELDFIHELINEEKGVAGG-RMMGGGFGGCIILLLKKNAVDRVVAHV 430
|
410 420
....*....|....*....|...
gi 445975554 357 AEQYEAKTGIKETFYVCKPSQGA 379
Cdd:PTZ00290 431 REKFKARFGVENDVYPVVAGDGA 453
|
|
| PLN02865 |
PLN02865 |
galactokinase |
25-361 |
2.85e-41 |
|
galactokinase
Pssm-ID: 215466 [Multi-domain] Cd Length: 423 Bit Score: 150.34 E-value: 2.85e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445975554 25 APGRVNLIGEHTDYNDGFVLPCAIDYQTVISCAPRDDRKVRVMAADYENQ----LDEFSLDAPIVAH---ENYQWANYVR 97
Cdd:PLN02865 35 SPYRICPLGAHIDHQGGTVSAMTINKGILLGFVPSGDPEVLLRSAQFEGEvrfrVDEIQHPIANVSSdskEESNWGDYAR 114
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445975554 98 GVVKHLQLRNNNF-GGVDMVISG-NVPQGAGLSSSASLEVAVGTVLQQLYHL---PLDGAQIAlngQEAENQFVGCNCGI 172
Cdd:PLN02865 115 GAVYALQSRGHALsQGITGYISGsEGLDSSGLSSSAAVGVAYLLALENANNLtvsPEDNIELD---RLIENEYLGLRNGI 191
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445975554 173 MDQLISALGKKDHALLIDCRSLGTKAVSMP-------KGVAVVIINSNFKRTLVGSE-YNTRREQCETGARFF------- 237
Cdd:PLN02865 192 LDQSAILLSRYGCLTFMDCKTLDHKLVSLQfqqpggeKPFKILLAFSGLRHALTNKPgYNLRVSECQEAARFLleasgnd 271
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445975554 238 -QQPALRDVTIEEFNAVAHELDPIVAKRVRHILTENARTVEAASALEQGDLKRMGELMAESHASMRDDFEITVPQIDTLV 316
Cdd:PLN02865 272 eLEPLLCNVEPEVYEAHKCKLEAVLARRAEHYFSENMRVIKGVEAWASGNLEEFGKLISASGLSSIENYECGCEPLIQLY 351
|
330 340 350 360
....*....|....*....|....*....|....*....|....*
gi 445975554 317 EIVKAVIGDKGGvRMTGGGFGGCIVALLPEELVPAVQQAVAEQYE 361
Cdd:PLN02865 352 EILLKAPGVYGA-RFSGAGFRGCCVAFVDAEMAEEAASFVRDEYE 395
|
|
| ERG12 |
COG1577 |
Mevalonate kinase [Lipid transport and metabolism]; Mevalonate kinase is part of the Pathway ... |
25-343 |
2.37e-30 |
|
Mevalonate kinase [Lipid transport and metabolism]; Mevalonate kinase is part of the Pathway/BioSystem: Isoprenoid biosynthesis
Pssm-ID: 441185 [Multi-domain] Cd Length: 277 Bit Score: 117.25 E-value: 2.37e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445975554 25 APGRVNLIGEHTDYNDGFVLPCAIDYQTVISCAPRDDRKVRVMAADYENQLDEFSLDAPIVAhenyqwanYVRGVVKH-L 103
Cdd:COG1577 1 APGKLILFGEHAVVYGQPAIAVAVDRRATVTVEPSDDDKLRIESPDLGGTLDLDPLADAALR--------YIKAAIEAaL 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445975554 104 QLRNNNFGGVDMVISGNVPQGAGLSSSASLEVAVGTVLQQLYHLPLDGAQIALNGQEAENQFVGcNCGIMDQLISALGkk 183
Cdd:COG1577 73 EYLGLPLKGFDIEIDSEIPRKRGLGSSAAVAVAVIRALAAFYGVELSKEELFKLALEAEKIVHG-NPSGLDTAASTYG-- 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445975554 184 dHALLIDcRSLGTKAVSMPKGVAVVIINSnfkrtlvGSEYNTRreqcetgarffqqPALRDVtieefnAVAHELDPivaK 263
Cdd:COG1577 150 -GPIYYQ-RGDRAEPLELPKNLPLVVGDT-------GVPASTK-------------ELVAKV------RKLKERNP---E 198
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445975554 264 RVRHILTENARTVEAA-SALEQGDLKRMGELMAESHAsMRDDFEITVPQIDTLVEIVKAViGDKGGvRMTGGGFGGCIVA 342
Cdd:COG1577 199 LYEAFLEEIGDLVEEAiEALEEGDLEALGELMNENHG-LLRALGVSTPELDRLVEAARKA-GALGA-KLTGAGGGGCVIA 275
|
.
gi 445975554 343 L 343
Cdd:COG1577 276 L 276
|
|
| GalKase_gal_bdg |
pfam10509 |
Galactokinase galactose-binding signature; This is the highly conserved galactokinase ... |
9-58 |
3.36e-21 |
|
Galactokinase galactose-binding signature; This is the highly conserved galactokinase signature sequence which appears to be present in all galactokinases irrespective of how many other ATP binding sites, etc that they carry. The function of this domain appears to be to bind galactose, and the domain is normally at the N-terminus of the enzymes, EC:2.7.1.6. This domain is associated with the families GHMP_kinases_C, pfam08544 and GHMP_kinases_N, pfam00288.
Pssm-ID: 463125 [Multi-domain] Cd Length: 50 Bit Score: 85.58 E-value: 3.36e-21
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 445975554 9 SLFANAFGYPATHTIQAPGRVNLIGEHTDYNDGFVLPCAIDYQTVISCAP 58
Cdd:pfam10509 1 EAFEELFGKEPVGVASAPGRVNLIGEHTDYNGGFVLPAAINLDTYVAVSP 50
|
|
| mevalon_kin |
TIGR00549 |
mevalonate kinase; This model represents mevalonate kinase, the third step in the mevalonate ... |
25-343 |
2.06e-19 |
|
mevalonate kinase; This model represents mevalonate kinase, the third step in the mevalonate pathway of isopentanyl pyrophosphate (IPP) biosynthesis. IPP is a common intermediate for a number of pathways including cholesterol biosynthesis. This model covers enzymes from eukaryotes, archaea and bacteria. The related enzyme from the same pathway, phosphmevalonate kinase, serves as an outgroup for this clade. Paracoccus exhibits two genes within the phosphomevalonate/mevalonate kinase family, one of which falls between trusted and noise cutoffs of this model. The degree of divergence is high, but if the trees created from this model are correct, the proper names of these genes have been swapped. [Central intermediary metabolism, Other]
Pssm-ID: 273130 [Multi-domain] Cd Length: 273 Bit Score: 86.96 E-value: 2.06e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445975554 25 APGRVNLIGEHtdyndgFV------LPCAID-YQTVISCAPRDDRKVRVMAadYENQLDEFSldapivahENYQWANYVR 97
Cdd:TIGR00549 1 APGKIILFGEH------AVvygepaIAAPIPlRTTVTVIESSDGSFIESDL--GRGSLDDAP--------DELDGLKYVL 64
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445975554 98 GVVKHLQLRNNNFgGVDMVISGNVPQGAGLSSSASLEVAVGTVLQQLYHLPLDGAQIALNGQEAENQFVGCNCGImDQLI 177
Cdd:TIGR00549 65 AEFLSRFSELNPP-PLEITIESEIPPGRGLGSSAAVAVALIRALADYFGSELSKEELAELANEAEKIAHGKPSGI-DTAT 142
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445975554 178 SALGkkdHALLIdCRSLGTKAVSMPKGVAVVIINSNFKRtlvgseyNTRReqcetgarffqqpalrdvtieefnAVAhel 257
Cdd:TIGR00549 143 STSG---GPVYF-EKGEGEFTKLISLDGYFVIADTGVSG-------STKE------------------------AVA--- 184
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445975554 258 dpivakRVRHILTENARTV------------EAASALEQGDLKRMGELMAESHASMrDDFEITVPQIDTLVEivkavIGD 325
Cdd:TIGR00549 185 ------RVRQLLERFPELIdsimdaigeltlEAKAALQDGDVESLGELMNINQGLL-KALGVSHPKLDQLVE-----IAR 252
|
330 340
....*....|....*....|.
gi 445975554 326 KGGV---RMTGGGFGGCIVAL 343
Cdd:TIGR00549 253 KAGAlgaKLTGAGGGGCMIAL 273
|
|
| PRK03926 |
PRK03926 |
mevalonate kinase; Provisional |
25-357 |
2.74e-15 |
|
mevalonate kinase; Provisional
Pssm-ID: 179677 [Multi-domain] Cd Length: 302 Bit Score: 75.86 E-value: 2.74e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445975554 25 APGRVNLIGEHTDYNDGFVLPCAIDYQTviscaprddrKVRVmaadyenqldEFSLDApIVAHENYQWA----NYVRGVV 100
Cdd:PRK03926 6 APGKIYLFGEHAVVYGKPAIACAIDLRT----------YVRA----------EFNDDS-IYIESDYGKTgekhPYVSAAI 64
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445975554 101 KHLQlRNNNFGGVDMVISGNVPQGAGLSSSASLEVAVGTVLQQLYHLPLDGAQIALNGQEAENQFVGCNCGImDQLISAL 180
Cdd:PRK03926 65 EKMR-EEADKDGVTVSITSQIPVGSGLGSSAAVTVATIGALNRLLGLGLSLEEIAKLGHKVELLVQGAASPT-DTYVSTM 142
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445975554 181 G------KKDHALLIDCrslgtkavsmpkgvAVVIINSN-FKRT--LVGseyNTRReqcetgarffqqpaLRdvtiEEFN 251
Cdd:PRK03926 143 GgfvtipDRKKLPFPEC--------------GIVVGYTGsSGSTkeLVA---NVRK--------------LK----EEYP 187
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445975554 252 AVaheLDPivakrvrhILTENARTVEAA-SALEQGDLKRMGELMAESHAsMRDDFEITVPQIDTLVEIVKAvigdKG--G 328
Cdd:PRK03926 188 EL---IEP--------ILSSIGKISEKGeELILSGDYVSLGELMNINQG-LLDALGVSTKELSELIYAART----AGalG 251
|
330 340
....*....|....*....|....*....
gi 445975554 329 VRMTGGGFGGCIVALLPEELVPAVQQAVA 357
Cdd:PRK03926 252 AKITGAGGGGCMVALAAPEKQSEVATAIK 280
|
|
| GHMP_kinases_N |
pfam00288 |
GHMP kinases N terminal domain; This family includes homoserine kinases, galactokinases and ... |
114-182 |
3.32e-15 |
|
GHMP kinases N terminal domain; This family includes homoserine kinases, galactokinases and mevalonate kinases.
Pssm-ID: 395225 [Multi-domain] Cd Length: 64 Bit Score: 69.50 E-value: 3.32e-15
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 445975554 114 DMVISGNVPQGAGLSSSASLEVAVGTVLQQLYHLPLdgaqiALNGQEAENQFVGCNCGIMDQLISALGK 182
Cdd:pfam00288 1 DIEIESNIPLGAGLGSSAALAVALLLALNELFGLPL-----AKLALEAEELAGGGRGGGMDVAASLYGG 64
|
|
| GHMP_kinases_C |
pfam08544 |
GHMP kinases C terminal; This family includes homoserine kinases, galactokinases and ... |
278-362 |
1.51e-11 |
|
GHMP kinases C terminal; This family includes homoserine kinases, galactokinases and mevalonate kinases.
Pssm-ID: 430063 [Multi-domain] Cd Length: 85 Bit Score: 59.79 E-value: 1.51e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445975554 278 AASALEQGDLKRMGELMAESHASM--RDDFEITVPQIDTLVEIVKAVIGdkgGVRMTGGGFGGCIVALLP-EELVPAVQQ 354
Cdd:pfam08544 1 LLEALLRGDLEELGKLLTESAESLepLLVVGILPPELDELLEALLELGL---GAKLSGSGGGPTVFALFKdEDDAEEVAR 77
|
....*...
gi 445975554 355 AVAEQYEA 362
Cdd:pfam08544 78 ALREAGKK 85
|
|
| PTZ00298 |
PTZ00298 |
mevalonate kinase; Provisional |
99-343 |
1.97e-07 |
|
mevalonate kinase; Provisional
Pssm-ID: 240351 [Multi-domain] Cd Length: 328 Bit Score: 52.16 E-value: 1.97e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445975554 99 VVKHLQLrNNNFGGVDMVISGNVPQGAGLSSSASLEVAVGTVLQQLYHLPLDGAQIALNGQEAENQFVGCNCGImDQLIS 178
Cdd:PTZ00298 82 VLRHLNI-DTSVDGLKMHLGGPLVPSSGIGASASDVVSLSRALSELYQLNLTEEEVNLSAFVGEGGYHGTPSGA-DNTAA 159
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445975554 179 ALGkkdhALLIDCRSLGT---KAVSMPKGVAVVIINS--NFKRTLVGSEYNTRREQcetgarffqQPALRDVTIEEFNAV 253
Cdd:PTZ00298 160 TYG----GLISYRRVNGKsvfKRIAFQQPLYLVVCSTgiTASTTKVVGDVRKLKEN---------QPTWFNRLLENYNAC 226
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445975554 254 AHEldpivakrvrhiltenartveAASALEQGDLKRMGELMAESHASMRddfEITV--PQIDTLVEIVKAVigDKGGVRM 331
Cdd:PTZ00298 227 VSE---------------------AKEALQKGNLFRVGELMNANHDLCQ---KLTVscRELDSIVQTCRTY--GALGAKM 280
|
250
....*....|..
gi 445975554 332 TGGGFGGCIVAL 343
Cdd:PTZ00298 281 SGTGRGGLVVAL 292
|
|
| PLN02677 |
PLN02677 |
mevalonate kinase |
116-363 |
1.23e-05 |
|
mevalonate kinase
Pssm-ID: 215363 [Multi-domain] Cd Length: 387 Bit Score: 46.75 E-value: 1.23e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445975554 116 VISGNVPQGAGLSSSASLEVAVGTVL-----------QQLYHLPLDGAQIALNGQ---EAENQFVGCNCGImDQLISALG 181
Cdd:PLN02677 133 VVTSELPLGSGLGSSAAFCVALSAALlaasdsisvstGGNGWSSLDETDLELVNKwafEGEKIIHGKPSGI-DNTVSTYG 211
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445975554 182 KkdhalLIDCRS--LGTKAVSMPkgVAVVIINsnfkrTLVGSeyNTRREQCETGARFFQQPALRDVTIEEFNAVAHELDP 259
Cdd:PLN02677 212 N-----MIKFKSgeLTRLQSNMP--LKMLITN-----TRVGR--NTKALVAGVSERALRHPDAMKSVFNAVDSISEELAT 277
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445975554 260 IV---AKRVRHIlTENARTVEAASALEQGDLKRMGElmaeSHASMRddfeiTVPQIDTLVEIVKavigdkggvRMTGGGF 336
Cdd:PLN02677 278 IIqspAEDELSI-TEKEEKLKELMEMNQGLLQCMGV----SHSSIE-----TVLRTTLKYKLVS---------KLTGAGG 338
|
250 260
....*....|....*....|....*..
gi 445975554 337 GGCIVALLPEELVPAVQQAVAEQYEAK 363
Cdd:PLN02677 339 GGCVLTLLPTLLSGTVVDKVIAELESS 365
|
|
| |
