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Conserved domains on  [gi|445939235|ref|WP_000017090|]
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type II secretion system secretin GspD [Leptospira interrogans]

Protein Classification

type II secretion system protein D( domain architecture ID 1004622)

type II secretion system protein D is involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins

CATH:  3.30.1370.120|3.55.50.30
Gene Ontology:  GO:0015628|GO:0015627|GO:0009279
PubMed:  28067918|30767847

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
type_II_gspD super family cl37135
type II secretion system protein D; In Gram-negative bacteria, proteins that have first ...
 55-567 0e+00

type II secretion system protein D; In Gram-negative bacteria, proteins that have first crossed the inner member by Sec-dependent protein transport can be exported across the outer membrane by type II secretion, also called the main terminal branch of the general secretion pathway. Members of this family are general secretion pathway protein D. In Yersinia enterocolitica, a second member of this family is part of a novel second type II secretion system specifically associated with virulence (See ). This family is closely homologous to the type IV pilus outer membrane secretin PilQ (TIGR02515) and to the type III secretion system pore YscC/HrcC (TIGR02516). [Protein fate, Protein and peptide secretion and trafficking]


The actual alignment was detected with superfamily member TIGR02517:

Pssm-ID: 274175 [Multi-domain]  Cd Length: 594  Bit Score: 544.67  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445939235   55 ANWRDTELNDFLKGMSAILKKNILLDESLKGKkITIISQKEIPIKNGFIFMKSVLESLGFGVVEEPDLISIVKIKDALAR 134
Cdd:TIGR02517   1 LNFVDADISTVVKAISDLTGKNFIIDPRVKGK-ITIISPRPVTEDEAYQLFLSALRAQGFAVVPEGNGYKIVVPRAAAKL 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445939235  135 SPIVrvgKELIPEEEVGDYRTITQVIPIENVKPEELEPILKRLTSPNTDVIVYRNTNTIVLSGSAADINKLLVLVSEFDV 214
Cdd:TIGR02517  80 SPGP---IEDGPAPGVGGDQFVTRVFPLRNISASELVPVLRPLVSPNGDVAAYPPTNTIVVTDYASNINRVARIIQQLDV 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445939235  215 KIE---EATPGSISSAGDI-------------------------------HIYTLEYSEAEKIAATLVKLDNPviQSEDL 260
Cdd:TIGR02517 157 DGAgsvEVIPLKNASAVDIadvlnkllgeggktdgggklsviapdrrnniLIRAGSPEALERIKKLISQLDVP--ASEGG 234

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445939235  261 GSERKPPPPGQPMPKVDKIKAVGH------------------------------------------KESNSVIVTATNAE 298
Cdd:TIGR02517 235 NVRVYYLRNADAEELAKTLQGVFGgggnepgsssspglggavnpggsqsaqaassasggsvsgsadKATNSLIITASPQD 314

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445939235  299 WAEIRKIIKVLDSARKQVLLEVLIVELTSSDLNDFGIDWRYKG--------EAFGQFNSGLSKEANIIN-SNGQVNPNIN 369
Cdd:TIGR02517 315 YKNIRAVIKQLDVRRAQVLVEAIIVEVSLDDALELGVQWLIAGtgggvnfsTGSPNSGSLLGASASAISlGSAGIGLLVT 394

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445939235  370 TLSGFSLGFLKAGSEQIIGILSANQGNENFNVLSAPQVLTVDNQEAEISVGQDVPVRTQSRNAGTGGTNAVTVDNYEYRP 449
Cdd:TIGR02517 395 SSSTTSGVGGTGGGPNLGVLLNALKQDTGFNVLSTPSLLTLDNQEAEINVGQEVPVLTGSYNTGTGGTNANPFNTYQRKD 474

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445939235  450 TGIKLKFTPHVNKNNKITLELFQEIKNIA--EIALAGGNPTFNRREIKTSISIENTQSIVIGGLISNDKQKRIIKIPFLG 527
Cdd:TIGR02517 475 VGIKLKVTPQINEGGTVRLEIYQEVSSVAptTVGSAASGPTFNKREIKTVVLVDNGDTVVLGGLIQDKTSESVTKVPLLG 554

                         570       580       590       600
                  ....*....|....*....|....*....|....*....|
gi 445939235  528 DIPYLGHLFKRTTEKIKKTNLMVFITPHILDSRETADKMT 567
Cdd:TIGR02517 555 DIPVLGWLFRSTTTERTKTNLMVFITPRIIRDPEDARALT 594
 
Name Accession Description Interval E-value
type_II_gspD TIGR02517
type II secretion system protein D; In Gram-negative bacteria, proteins that have first ...
 55-567 0e+00

type II secretion system protein D; In Gram-negative bacteria, proteins that have first crossed the inner member by Sec-dependent protein transport can be exported across the outer membrane by type II secretion, also called the main terminal branch of the general secretion pathway. Members of this family are general secretion pathway protein D. In Yersinia enterocolitica, a second member of this family is part of a novel second type II secretion system specifically associated with virulence (See ). This family is closely homologous to the type IV pilus outer membrane secretin PilQ (TIGR02515) and to the type III secretion system pore YscC/HrcC (TIGR02516). [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 274175 [Multi-domain]  Cd Length: 594  Bit Score: 544.67  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445939235   55 ANWRDTELNDFLKGMSAILKKNILLDESLKGKkITIISQKEIPIKNGFIFMKSVLESLGFGVVEEPDLISIVKIKDALAR 134
Cdd:TIGR02517   1 LNFVDADISTVVKAISDLTGKNFIIDPRVKGK-ITIISPRPVTEDEAYQLFLSALRAQGFAVVPEGNGYKIVVPRAAAKL 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445939235  135 SPIVrvgKELIPEEEVGDYRTITQVIPIENVKPEELEPILKRLTSPNTDVIVYRNTNTIVLSGSAADINKLLVLVSEFDV 214
Cdd:TIGR02517  80 SPGP---IEDGPAPGVGGDQFVTRVFPLRNISASELVPVLRPLVSPNGDVAAYPPTNTIVVTDYASNINRVARIIQQLDV 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445939235  215 KIE---EATPGSISSAGDI-------------------------------HIYTLEYSEAEKIAATLVKLDNPviQSEDL 260
Cdd:TIGR02517 157 DGAgsvEVIPLKNASAVDIadvlnkllgeggktdgggklsviapdrrnniLIRAGSPEALERIKKLISQLDVP--ASEGG 234

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445939235  261 GSERKPPPPGQPMPKVDKIKAVGH------------------------------------------KESNSVIVTATNAE 298
Cdd:TIGR02517 235 NVRVYYLRNADAEELAKTLQGVFGgggnepgsssspglggavnpggsqsaqaassasggsvsgsadKATNSLIITASPQD 314

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445939235  299 WAEIRKIIKVLDSARKQVLLEVLIVELTSSDLNDFGIDWRYKG--------EAFGQFNSGLSKEANIIN-SNGQVNPNIN 369
Cdd:TIGR02517 315 YKNIRAVIKQLDVRRAQVLVEAIIVEVSLDDALELGVQWLIAGtgggvnfsTGSPNSGSLLGASASAISlGSAGIGLLVT 394

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445939235  370 TLSGFSLGFLKAGSEQIIGILSANQGNENFNVLSAPQVLTVDNQEAEISVGQDVPVRTQSRNAGTGGTNAVTVDNYEYRP 449
Cdd:TIGR02517 395 SSSTTSGVGGTGGGPNLGVLLNALKQDTGFNVLSTPSLLTLDNQEAEINVGQEVPVLTGSYNTGTGGTNANPFNTYQRKD 474

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445939235  450 TGIKLKFTPHVNKNNKITLELFQEIKNIA--EIALAGGNPTFNRREIKTSISIENTQSIVIGGLISNDKQKRIIKIPFLG 527
Cdd:TIGR02517 475 VGIKLKVTPQINEGGTVRLEIYQEVSSVAptTVGSAASGPTFNKREIKTVVLVDNGDTVVLGGLIQDKTSESVTKVPLLG 554

                         570       580       590       600
                  ....*....|....*....|....*....|....*....|
gi 445939235  528 DIPYLGHLFKRTTEKIKKTNLMVFITPHILDSRETADKMT 567
Cdd:TIGR02517 555 DIPVLGWLFRSTTTERTKTNLMVFITPRIIRDPEDARALT 594
PulD COG1450
Type II secretory pathway component GspD/PulD (secretin) [Intracellular trafficking, secretion, ...
 277-567 4.21e-88

Type II secretory pathway component GspD/PulD (secretin) [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 441059 [Multi-domain]  Cd Length: 333  Bit Score: 276.42  E-value: 4.21e-88
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445939235 277 DKIKAVGHKESNSVIVTATNAEWAEIRKIIKVLDSARKQVLLEVLIVELTSSDLNDFGIDWRYKGEAFGQFNSGLSKEAN 356
Cdd:COG1450   42 AGVSVVADPRTNSLIVRATPEQLREIEELIEQLDVPRRQVLIEAKIVEVSLSDLRELGIDWSALGGNGGGVNFGGTGSLG 121

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445939235 357 IINSNGQVNpnintlSGFSLGFLkaGSEQIIGILSANQGNENFNVLSAPQVLTVDNQEAEISVGQDVPVRTQSRNAGTGG 436
Cdd:COG1450  122 SLAAAGSLG------GGLNLGLL--GGGNFGALLNALESNGDANVLSSPSILTLNNQEAVIKVGQTVPYVTGSTTTSSTG 193

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445939235 437 TNAVTVdnyEYRPTGIKLKFTPHVNKNNKITLELFQEIKNIAEIALAGGN--PTFNRREIKTSISIENTQSIVIGGLISN 514
Cdd:COG1450  194 NPTTTI---EYVDVGITLKVTPQINEDGTVTLDINPEVSSVTGSTTGGGNglPTINKREISTTVRVKDGQTVVLGGLIRD 270

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|...
gi 445939235 515 DKQKRIIKIPFLGDIPYLGHLFKRTTEKIKKTNLMVFITPHILDSRETADKMT 567
Cdd:COG1450  271 EESESESKVPLLGDIPLLGRLFRSTSKSKEKTELVIFITPTIIRDGEDAQALT 323
Secretin pfam00263
Bacterial type II and III secretion system protein;
392-557 2.05e-55

Bacterial type II and III secretion system protein;


Pssm-ID: 459738 [Multi-domain]  Cd Length: 159  Bit Score: 184.64  E-value: 2.05e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445939235  392 ANQGNENFNVLSAPQVLTVDNQEAEISVGQDVPVRTQSRNAGTGGTNavtvdnYEYRPTGIKLKFTPHVNKNNKITLELF 471
Cdd:pfam00263   1 ALEQNGKAKILSSPSLLTLDNQEASIKVGQEVPVPTTSTTGGTTTTT------VEFKDAGLSLKVTPQVTPDGTITLKIN 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445939235  472 QEIKNIAEIAlAGGNPTFNRREIKTSISIENTQSIVIGGLISNDKQKRIIKIPFLGDIPYLGHLFKRTTEKIKKTNLMVF 551
Cdd:pfam00263  75 PEVSSPDGNG-GNGVPTINTREISTTVRVKDGQTVVIGGLIQEEDSETESKVPLLGDIPLLGALFRSTSKSKEKTELLIF 153


                  ....*.
gi 445939235  552 ITPHIL 557
Cdd:pfam00263 154 ITPRIV 159
IV PHA00019
phage assembly protein
 287-557 4.38e-34

phage assembly protein


Pssm-ID: 222772 [Multi-domain]  Cd Length: 428  Bit Score: 134.56  E-value: 4.38e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445939235 287 SNSVIVTATNAEWAEIRKIIKVLDSARKQVLLEVLIVELTSSDlndfGIDWRYK-GEAFGqfnsglSKEANIINSNGQVN 365
Cdd:PHA00019 170 TNSLVVSGSASQLPALADFISAIDVPRRQVLIEALIFETSLGD----GVDLSFAaGLASG------GKVAGGFNTARLTT 239

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445939235 366 pNINTLSGfSLGFLKAGSeqIIGILSANQGNENFNVLSAPQVLTVDNQEAEISVGQDVPVRT--QSRNAGTGGTNAVTVd 443
Cdd:PHA00019 240 -VLSSAGG-SFGIFNGNV--LGLSVKALENSSNSRVLSRPRILTLSGQSGYISVGQNVPFVTgrVTGEAANVNNPFQTI- 314

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445939235 444 nyEYRPTGIKLKFTPHVNKNNKITLELFQEIKNIAEIALAGGNPTfNRREIKTSISIENTQSIVIGGLISNDKQKRIIKI 523
Cdd:PHA00019 315 --ERKDVGVSLEVTPVVMGDGQLVLDIDTKADSLSDSTIASDIIT-NQRSLQTTVQVKDGQTLLLGGLISSNNTDGDSSV 391

                        250       260       270
                 ....*....|....*....|....*....|....
gi 445939235 524 PFLGDIPYLGHLFKRTTEKIKKTNLMVFITPHIL 557
Cdd:PHA00019 392 PFLSKIPLIGWLFRSKSDSNEQRTLYVLLTARVI 425
 
Name Accession Description Interval E-value
type_II_gspD TIGR02517
type II secretion system protein D; In Gram-negative bacteria, proteins that have first ...
 55-567 0e+00

type II secretion system protein D; In Gram-negative bacteria, proteins that have first crossed the inner member by Sec-dependent protein transport can be exported across the outer membrane by type II secretion, also called the main terminal branch of the general secretion pathway. Members of this family are general secretion pathway protein D. In Yersinia enterocolitica, a second member of this family is part of a novel second type II secretion system specifically associated with virulence (See ). This family is closely homologous to the type IV pilus outer membrane secretin PilQ (TIGR02515) and to the type III secretion system pore YscC/HrcC (TIGR02516). [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 274175 [Multi-domain]  Cd Length: 594  Bit Score: 544.67  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445939235   55 ANWRDTELNDFLKGMSAILKKNILLDESLKGKkITIISQKEIPIKNGFIFMKSVLESLGFGVVEEPDLISIVKIKDALAR 134
Cdd:TIGR02517   1 LNFVDADISTVVKAISDLTGKNFIIDPRVKGK-ITIISPRPVTEDEAYQLFLSALRAQGFAVVPEGNGYKIVVPRAAAKL 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445939235  135 SPIVrvgKELIPEEEVGDYRTITQVIPIENVKPEELEPILKRLTSPNTDVIVYRNTNTIVLSGSAADINKLLVLVSEFDV 214
Cdd:TIGR02517  80 SPGP---IEDGPAPGVGGDQFVTRVFPLRNISASELVPVLRPLVSPNGDVAAYPPTNTIVVTDYASNINRVARIIQQLDV 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445939235  215 KIE---EATPGSISSAGDI-------------------------------HIYTLEYSEAEKIAATLVKLDNPviQSEDL 260
Cdd:TIGR02517 157 DGAgsvEVIPLKNASAVDIadvlnkllgeggktdgggklsviapdrrnniLIRAGSPEALERIKKLISQLDVP--ASEGG 234

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445939235  261 GSERKPPPPGQPMPKVDKIKAVGH------------------------------------------KESNSVIVTATNAE 298
Cdd:TIGR02517 235 NVRVYYLRNADAEELAKTLQGVFGgggnepgsssspglggavnpggsqsaqaassasggsvsgsadKATNSLIITASPQD 314

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445939235  299 WAEIRKIIKVLDSARKQVLLEVLIVELTSSDLNDFGIDWRYKG--------EAFGQFNSGLSKEANIIN-SNGQVNPNIN 369
Cdd:TIGR02517 315 YKNIRAVIKQLDVRRAQVLVEAIIVEVSLDDALELGVQWLIAGtgggvnfsTGSPNSGSLLGASASAISlGSAGIGLLVT 394

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445939235  370 TLSGFSLGFLKAGSEQIIGILSANQGNENFNVLSAPQVLTVDNQEAEISVGQDVPVRTQSRNAGTGGTNAVTVDNYEYRP 449
Cdd:TIGR02517 395 SSSTTSGVGGTGGGPNLGVLLNALKQDTGFNVLSTPSLLTLDNQEAEINVGQEVPVLTGSYNTGTGGTNANPFNTYQRKD 474

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445939235  450 TGIKLKFTPHVNKNNKITLELFQEIKNIA--EIALAGGNPTFNRREIKTSISIENTQSIVIGGLISNDKQKRIIKIPFLG 527
Cdd:TIGR02517 475 VGIKLKVTPQINEGGTVRLEIYQEVSSVAptTVGSAASGPTFNKREIKTVVLVDNGDTVVLGGLIQDKTSESVTKVPLLG 554

                         570       580       590       600
                  ....*....|....*....|....*....|....*....|
gi 445939235  528 DIPYLGHLFKRTTEKIKKTNLMVFITPHILDSRETADKMT 567
Cdd:TIGR02517 555 DIPVLGWLFRSTTTERTKTNLMVFITPRIIRDPEDARALT 594
PulD COG1450
Type II secretory pathway component GspD/PulD (secretin) [Intracellular trafficking, secretion, ...
 277-567 4.21e-88

Type II secretory pathway component GspD/PulD (secretin) [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 441059 [Multi-domain]  Cd Length: 333  Bit Score: 276.42  E-value: 4.21e-88
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445939235 277 DKIKAVGHKESNSVIVTATNAEWAEIRKIIKVLDSARKQVLLEVLIVELTSSDLNDFGIDWRYKGEAFGQFNSGLSKEAN 356
Cdd:COG1450   42 AGVSVVADPRTNSLIVRATPEQLREIEELIEQLDVPRRQVLIEAKIVEVSLSDLRELGIDWSALGGNGGGVNFGGTGSLG 121

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445939235 357 IINSNGQVNpnintlSGFSLGFLkaGSEQIIGILSANQGNENFNVLSAPQVLTVDNQEAEISVGQDVPVRTQSRNAGTGG 436
Cdd:COG1450  122 SLAAAGSLG------GGLNLGLL--GGGNFGALLNALESNGDANVLSSPSILTLNNQEAVIKVGQTVPYVTGSTTTSSTG 193

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445939235 437 TNAVTVdnyEYRPTGIKLKFTPHVNKNNKITLELFQEIKNIAEIALAGGN--PTFNRREIKTSISIENTQSIVIGGLISN 514
Cdd:COG1450  194 NPTTTI---EYVDVGITLKVTPQINEDGTVTLDINPEVSSVTGSTTGGGNglPTINKREISTTVRVKDGQTVVLGGLIRD 270

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|...
gi 445939235 515 DKQKRIIKIPFLGDIPYLGHLFKRTTEKIKKTNLMVFITPHILDSRETADKMT 567
Cdd:COG1450  271 EESESESKVPLLGDIPLLGRLFRSTSKSKEKTELVIFITPTIIRDGEDAQALT 323
Secretin pfam00263
Bacterial type II and III secretion system protein;
392-557 2.05e-55

Bacterial type II and III secretion system protein;


Pssm-ID: 459738 [Multi-domain]  Cd Length: 159  Bit Score: 184.64  E-value: 2.05e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445939235  392 ANQGNENFNVLSAPQVLTVDNQEAEISVGQDVPVRTQSRNAGTGGTNavtvdnYEYRPTGIKLKFTPHVNKNNKITLELF 471
Cdd:pfam00263   1 ALEQNGKAKILSSPSLLTLDNQEASIKVGQEVPVPTTSTTGGTTTTT------VEFKDAGLSLKVTPQVTPDGTITLKIN 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445939235  472 QEIKNIAEIAlAGGNPTFNRREIKTSISIENTQSIVIGGLISNDKQKRIIKIPFLGDIPYLGHLFKRTTEKIKKTNLMVF 551
Cdd:pfam00263  75 PEVSSPDGNG-GNGVPTINTREISTTVRVKDGQTVVIGGLIQEEDSETESKVPLLGDIPLLGALFRSTSKSKEKTELLIF 153


                  ....*.
gi 445939235  552 ITPHIL 557
Cdd:pfam00263 154 ITPRIV 159
HofQ COG4796
Type II secretory pathway, component HofQ [Intracellular trafficking, secretion, and vesicular ...
 287-562 1.78e-53

Type II secretory pathway, component HofQ [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 443824 [Multi-domain]  Cd Length: 570  Bit Score: 191.61  E-value: 1.78e-53
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445939235 287 SNSVIVTATNAEWAEIRKIIKVLDSARKQVLLEVLIVELTSSDLNDFGIDWRYKGE--------AFGQFNSGLSKEANII 358
Cdd:COG4796  295 TNTLIVRDTPSKLEEIRRLIAKLDIPVRQVLIEARIVEASDSFSRELGVRWGGSGAngtgnnrgGIGGSLNGTTAGTPLL 374

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445939235 359 NSNGQVN-PNINTLSGFSLGFLKAGSEQIIGI-LSANQGNENFNVLSAPQVLTVDNQEAEISVGQDVPVRTQSRNAGTgg 436
Cdd:COG4796  375 PDGLNVNlPAANPAGSLGLTLAKLGGGRLLDLeLSALEAEGKGEIISSPRVITADQQEASIEQGTEIPYQESSSSGAT-- 452

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445939235 437 tnavtvdNYEYRPTGIKLKFTPHVNKNNKITLELfqEI-KNIAEIALAGGNPTFNRREIKTSISIENTQSIVIGGLISND 515
Cdd:COG4796  453 -------SVEFKEAVLSLEVTPQITPDGRIILDL--DVsKDSPGETVAGGVPAIDTKEIKTQVLVENGETVVLGGIYEQT 523

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*..
gi 445939235 516 KQKRIIKIPFLGDIPYLGHLFKRTTEKIKKTNLMVFITPHILDSRET 562
Cdd:COG4796  524 ESNSVDKVPFLGDIPLLGWLFKNTTKTDEKRELLIFITPRIVKDALA 570
IV_pilus_PilQ TIGR02515
type IV pilus secretin (or competence protein) PilQ; A number of proteins homologous to PilQ ...
 287-558 9.08e-48

type IV pilus secretin (or competence protein) PilQ; A number of proteins homologous to PilQ are involved in type IV pilus formation, competence for transformation, type III secretion, and type II secretion (also called the main terminal branch of the general secretion pathway). Members of this family include PilQ itself, which is a component of the type IV pilus structure, from a number of species. In Haemophilus influenzae, the member of this family is associated with competence for transformation with exogenous DNA rather than with formation of a type IV pilus; the surface structure required for competence may be considered an unusual, incomplete type IV pilus structure. [Cell envelope, Surface structures]


Pssm-ID: 274173 [Multi-domain]  Cd Length: 418  Bit Score: 172.50  E-value: 9.08e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445939235  287 SNSVIVTATNAEWAEIRKIIKVLDSARKQVLLEVLIVELTSSDLNDFGIDW------RYKGEAFGQF----NSGLSKEAN 356
Cdd:TIGR02515 139 TNTLIVTDTPENLARIRKLIAELDIPVRQVLIEARIVEATDSFSRELGVRWgitdknGNGNGTAGGIggnnGTTATGAGG 218

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445939235  357 IINSNGQVNPNIN-----TLSGFSLGFLKAGSEQIIGI-LSANQGNENFNVLSAPQVLTVDNQEAEISVGQDVPVRTQSR 430
Cdd:TIGR02515 219 TGNPPFGDNLNVNlatatTAAGISFALGKIGSGRLLDLeLSALESEGKGEIISSPRVLTANNKEAKIEQGTEIPYQQTSS 298

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445939235  431 NAGTggtnavtvdNYEYRPTGIKLKFTPHVNKNNKITLELfqEIKN--IAEIALA-GGNPTFNRREIKTSISIENTQSIV 507
Cdd:TIGR02515 299 SGAT---------SVEFKEAVLSLEVTPQITPDGRIIMDL--LVSKdsPGVVAQAgGGVPAIDKQEINTQVLVKNGETVV 367

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|.
gi 445939235  508 IGGLISNDKQKRIIKIPFLGDIPYLGHLFKRTTEKIKKTNLMVFITPHILD 558
Cdd:TIGR02515 368 IGGIYEQTQTNSEDKVPLLGDIPVLGNLFKKTGKSDEKSELLIFITPRIVN 418
CpaC COG4964
Flp pilus assembly protein, secretin CpaC [Intracellular trafficking, secretion, and vesicular ...
 278-556 6.79e-44

Flp pilus assembly protein, secretin CpaC [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 443990 [Multi-domain]  Cd Length: 456  Bit Score: 162.73  E-value: 6.79e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445939235 278 KIKAVGhkesNSVIVTATNAEWAEIRKII----------KVLD----SARKQVLLEVLIVELTSSDLNDFGIDWRYKGEA 343
Cdd:COG4964  129 RVRAVG----DRVVLSGTVSSAADADRAVdlaeayagggKVINlltvGGPQQVMLKVRVAEVSRSVLKQLGINWSGLGSS 204

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445939235 344 fGQFNSGLskeaniiNSNGQVNPNINTLSGFSLGFLKAGSEQIIGILSANQGNENFNVLSAPQVLTVDNQEAEISVGQDV 423
Cdd:COG4964  205 -GGFSFGL-------LTGGLLSGLLGGATAGAFSGFGFGNASISATLDALEQNGLARVLAEPNLTALSGETASFLAGGEF 276

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445939235 424 PVRTqsrnagTGGTNAVTVdnyEYRPTGIKLKFTPHVNKNNKITLELFQEIKNI---AEIALAGGN-PTFNRREIKTSIS 499
Cdd:COG4964  277 PIPV------AQGDGTITV---EYKEFGVSLNFTPTVLSNGRISLKVAPEVSELdpsNAVTLNGITiPGLTTRRAETTVE 347

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 445939235 500 IENTQSIVIGGLISNDKQKRIIKIPFLGDIPYLGHLFKRTTEKIKKTNLMVFITPHI 556
Cdd:COG4964  348 LRSGQSFAIAGLLSSNTRQNVSKVPGLGDIPILGALFRSRSFQRNETELVIIVTPYL 404
pilus_MshL TIGR02519
pilus (MSHA type) biogenesis protein MshL; Members of this family are predicted secretins, ...
 285-557 1.21e-34

pilus (MSHA type) biogenesis protein MshL; Members of this family are predicted secretins, that is, outer membrane pore proteins associated with delivery of proteins from periplasm to the outside of the cell. Related families include GspD of type II secretion (TIGR02517), the YscC/HrcC family from type III secretion (TIGR02516), and the PilQ secretin of type IV pilus formation (TIGR02515). Members of this family are found in gene clusters associated with MSHA (mannose-sensitive hemagglutinin) and related pili, and appear to be the secretin of this pilus system. [Cell envelope, Surface structures]


Pssm-ID: 274176 [Multi-domain]  Cd Length: 290  Bit Score: 132.89  E-value: 1.21e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445939235  285 KESNSVIVTATNAEWAEIRKIIKVL-DSARKQVLLEVLIVELTSSDLNDFGIDWRYKGEAFGQFNSGLSKEANIINSNGQ 363
Cdd:TIGR02519   5 PEAGLLTVTATPAQIRRVEEYLESLqERIHRQVLIEAKILEVTLSDNHQQGIDWSNFNGSGLARYKALGAANSNDSSGNQ 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445939235  364 VNPNINTLSGFSLGFLKAGSEQIIGILSANQGNENFNVLSAPQVLTVDNQEAEISVGQDVPVRTQSRNAG-TGGTNAVTV 442
Cdd:TIGR02519  85 FSSGLGFLDNIGLPTGVNSGFGFDSIINFLATFGDTKVLSNPKVMALNNQPAVISVGDNIRYVTEESSTGtTGGTTSTAS 164

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445939235  443 DNYEYRP--TGIKLKFTPHVNKNNKITLEL--------FQEIK-----NIAEIALaggnPTFNRREIKTSISIENTQSIV 507
Cdd:TIGR02519 165 SDTRVDSvfSGIVLGVTPQISDDGKVILNVhpsisevkPQSIDlnpvgNGAEVAL----PEISVKEMSSVLRVKDGDTVV 240

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|
gi 445939235  508 IGGLISNDKQKRIIKIPFLGDIPYLGHLFKRTTEKIKKTNLMVFITPHIL 557
Cdd:TIGR02519 241 LGGLIDKKKSNTKTGLPFLGDIPGLGYLFGYKSKSKKKTELVIIIRPSVV 290
IV PHA00019
phage assembly protein
 287-557 4.38e-34

phage assembly protein


Pssm-ID: 222772 [Multi-domain]  Cd Length: 428  Bit Score: 134.56  E-value: 4.38e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445939235 287 SNSVIVTATNAEWAEIRKIIKVLDSARKQVLLEVLIVELTSSDlndfGIDWRYK-GEAFGqfnsglSKEANIINSNGQVN 365
Cdd:PHA00019 170 TNSLVVSGSASQLPALADFISAIDVPRRQVLIEALIFETSLGD----GVDLSFAaGLASG------GKVAGGFNTARLTT 239

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445939235 366 pNINTLSGfSLGFLKAGSeqIIGILSANQGNENFNVLSAPQVLTVDNQEAEISVGQDVPVRT--QSRNAGTGGTNAVTVd 443
Cdd:PHA00019 240 -VLSSAGG-SFGIFNGNV--LGLSVKALENSSNSRVLSRPRILTLSGQSGYISVGQNVPFVTgrVTGEAANVNNPFQTI- 314

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445939235 444 nyEYRPTGIKLKFTPHVNKNNKITLELFQEIKNIAEIALAGGNPTfNRREIKTSISIENTQSIVIGGLISNDKQKRIIKI 523
Cdd:PHA00019 315 --ERKDVGVSLEVTPVVMGDGQLVLDIDTKADSLSDSTIASDIIT-NQRSLQTTVQVKDGQTLLLGGLISSNNTDGDSSV 391

                        250       260       270
                 ....*....|....*....|....*....|....
gi 445939235 524 PFLGDIPYLGHLFKRTTEKIKKTNLMVFITPHIL 557
Cdd:PHA00019 392 PFLSKIPLIGWLFRSKSDSNEQRTLYVLLTARVI 425
hofQ PRK13568
DNA uptake porin HofQ;
232-554 1.99e-29

DNA uptake porin HofQ;


Pssm-ID: 237430 [Multi-domain]  Cd Length: 381  Bit Score: 120.22  E-value: 1.99e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445939235 232 IYTLEYSEAEKIAATLvkldnpviQSED--LGSERKPPPpgqpmpkVDKikavghkESNSVIVTATNAEWAEIRKIIKVL 309
Cdd:PRK13568  86 TLTLQYADAEEVADSL--------QSQRggLLSPRGSVT-------ADK-------RTNTLLIRDTPAALAQLKNWLIEL 143

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445939235 310 DSARKQVLLEVLIVELTSSDLNDFGIDWRYKGEAFG-------QFNSGLSKEaniinsngqvNPNINtlSGFSLGflKAG 382
Cdd:PRK13568 144 DLPLQQVQLAAHIVTISSESLQELGVRWGMGEGKQGntalrinDFNVNLPLP----------NPAAS--AGFHLA--RLG 209

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445939235 383 SEQIIGILSANQGNENFNVLSAPQVLTVDNQEAEISVGQDVPVRTQSrnaGTGGTNAVtvdnyEYRPTGIKLKFTPHVNK 462
Cdd:PRK13568 210 GRLLDLELSALEQENQVDIIASPRLFTSHQQTASIKQGTEIPYTVSS---GKSGSTSI-----EFKEAVLGMEVTPKILR 281

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445939235 463 NNKITLELfQEIKNIAEIALAGGNP---TFNRREIKTSISIENTQSIVIGGLISNDKQKRIIKIPFLGDIPYLGHLFKRT 539
Cdd:PRK13568 282 NGRITLKL-KISQNMPGRTIKRGEGemlAIDKQEIQTQVTVKDGETIVLGGIFQQQKRQSVNKVPLLGDIPLLGALFRQD 360

                        330
                 ....*....|....*
gi 445939235 540 TEKIKKTNLMVFITP 554
Cdd:PRK13568 361 TQQQSRRELVIFITP 375
type_III_yscC TIGR02516
type III secretion outer membrane pore, YscC/HrcC family; A number of proteins homologous to ...
 159-559 5.71e-28

type III secretion outer membrane pore, YscC/HrcC family; A number of proteins homologous to the type IV pilus secretin PilQ (TIGR02515) are involved in type IV pilus formation, competence for transformation, type III secretion, and type II secretion (also called the main terminal branch of the general secretion pathway). The clade described by this model contains the outer membrane pore proteins of bacterial type III secretion systems, typified by YscC for animal pathogens and HrcC for plant pathogens. [Protein fate, Protein and peptide secretion and trafficking, Cellular processes, Pathogenesis]


Pssm-ID: 274174 [Multi-domain]  Cd Length: 462  Bit Score: 117.09  E-value: 5.71e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445939235  159 VIPIENVKPEELEPILKR--LTSPNTDVIVYRNTNTIVLSGSAADINkllvLVSEFDVKIEEATPGSISSAGDIHIYTLE 236
Cdd:TIGR02516  79 VISPRPLSANELKKALRRsgLYDPRFPWRGDPEEGTVYVSGPPAYID----LVRNAATALEKQDQGRAGNRQVVKVFPLK 154

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445939235  237 YSEAEKIAATLV--KLDNPVIQS----------EDLGSERKPpppgqpmpkvDKIKAVGHKESNSVIVTATNAEWAEIRK 304
Cdd:TIGR02516 155 YASASDRTYNYRdqKVTIPGVATilrrllsggrQGAGGGRAS----------ASPKISADPRTNAVLIRDRPERMAIYEQ 224

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445939235  305 IIKVLDSARKQVLLEVLIVELTSSDLNDFGIDWRYkgeAFGQFNSGLSKEANIINSNGQVNPNINTLsgfslgflkaGSE 384
Cdd:TIGR02516 225 LIQQLDVPPRLIEISAWIIDIDASDLSQLGVDWQA---TLGAGDRQTGFNVSAGAGLGATGSSIVTS----------DGD 291

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445939235  385 QIIGILSANQGNENFNVLSAPQVLTVDNQEAEISVGQDVPVRTQsrnagtgGTNAVTVDNYEYrptGIKLKFTPHV--NK 462
Cdd:TIGR02516 292 YFMARVNALEQTGKAKIVSRPSVLTLENVQAVLDNNRTFYVKVS-------GERVADLESVTA---GTSLRVTPRVigDE 361

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445939235  463 NNKITLELFQEIKNIAEIALAGGN----PTFNRREIKTSISIENTQSIVIGGLISNDKQKRIIKIPFLGDIPYLGHLFKR 538
Cdd:TIGR02516 362 GAQRQIKLNVDIEDGQQKTDGTSTvdalPEIKRTEINTQARVGHGQSLLIGGYYRDESADSVDGIPLLGDIPLLGNLFRS 441

                         410       420
                  ....*....|....*....|.
gi 445939235  539 TTEKIKKTNLMVFITPHILDS 559
Cdd:TIGR02516 442 TSKEKSRVVRLFLITPKIVRD 462
hofQ PRK10560
outer membrane porin HofQ; Provisional
 233-560 6.62e-20

outer membrane porin HofQ; Provisional


Pssm-ID: 182549 [Multi-domain]  Cd Length: 386  Bit Score: 91.80  E-value: 6.62e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445939235 233 YTLEYSEAEKIAATLVKLDNPviqsedLGSerkppppgqpmPKVDKikavghkESNSVIVTATNAEWAEIRKIIKVLDSA 312
Cdd:PRK10560  96 ITLQYADAGELAKAGEKLLSA------KGS-----------MTVDK-------RTNRLLLRDNKTALSALEQWVAQMDLP 151

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445939235 313 RKQVLLEVLIVELTSSDLNDFGIDWRYkGEAFGQFNSG----LSKEANIINSNGQVNPNINTLSGFSLGFLkagseqiig 388
Cdd:PRK10560 152 VGQVELAAHIVTINEKSLRELGVKWTL-ADAQQAGGVGqvttLGSDLSVATATTRVGFNIGRINGRLLDLE--------- 221

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445939235 389 iLSANQGNENFNVLSAPQVLTVDNQEAEISVGQDVPVRTQSrnaGTGGTNAVtvdnyEYRPTGIKLKFTPHVNKNNKITL 468
Cdd:PRK10560 222 -LSALEQKQQLDIIASPRLLASHLQPASIKQGSEIPYQVSS---GESGATSV-----EFKEAVLGMEVTPTVLQKGRIRL 292

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445939235 469 ELfQEIKNIAEIALA---GGNPTFNRREIKTSISIENTQSIVIGGLISNDKQKRIIKIPFLGDIPYLGHLFKRTTEKIKK 545
Cdd:PRK10560 293 KL-HISQNVPGQVLQqadGEVLAIDKQEIETQVEVKSGETLALGGIFSRKNKSGQDSVPLLGDIPWLGQLFRHDGKEDER 371

                        330
                 ....*....|....*
gi 445939235 546 TNLMVFITPHILDSR 560
Cdd:PRK10560 372 RELVVFITPRLVSSE 386
PRK15346 PRK15346
EscC/YscC/HrcC family type III secretion system outer membrane ring protein;
288-542 2.30e-15

EscC/YscC/HrcC family type III secretion system outer membrane ring protein;


Pssm-ID: 237950 [Multi-domain]  Cd Length: 499  Bit Score: 78.96  E-value: 2.30e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445939235 288 NSVIVTATNAEWAEIRKIIKVLDSARKQVLLEVLIVELTSSDLNDFGIDWRYKGEAFG---QFNSGLskeaniinsNGQV 364
Cdd:PRK15346 245 NAVIVRDRAANMAIYRSLITQLDQRPQMIEISVSIIDVDAGDINQLGIDWSASASLGGgkiSFNSGF---------ADGN 315

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445939235 365 NPNINTLSGFSLGFLKAgseqiigiLSANQGNENFNVLSAPQVLTVDNQEAEISvgQDVPVRTQSRNAGTGGTNAVTvdn 444
Cdd:PRK15346 316 ASGFSTVISNTGNFMVR--------LNALEKNSKAKILSQPSVVTLNNIQAVLD--KNVTFYTKLQGEKVAKLESIT--- 382

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445939235 445 yeyrpTGIKLKFTPHV---NKNNKITLEL-FQEIKNIAEIALAGGNPTFNRREIKTSISIENTQSIVIGGLISNDKQKRI 520
Cdd:PRK15346 383 -----TGSLLRVTPRLiddNGTQKVMLNLnIQDGQQSATQSETDPLPEVQNSEIATQATLKAGQSLLLGGFIQDKQIESQ 457

                        250       260
                 ....*....|....*....|..
gi 445939235 521 IKIPFLGDIPYLGHLFKRTTEK 542
Cdd:PRK15346 458 NKIPLLGDIPLIGGLFRSTDKQ 479
PRK15339 PRK15339
EscC/YscC/HrcC family type III secretion system outer membrane ring protein;
277-564 1.02e-13

EscC/YscC/HrcC family type III secretion system outer membrane ring protein;


Pssm-ID: 237948 [Multi-domain]  Cd Length: 559  Bit Score: 74.04  E-value: 1.02e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445939235 277 DKIKAVGHKESNSVIVTATNAEWAEIRKIIKVLDSARKQVLLEVLIVELTSSDLNDFGIDWryKGEAfgQFNSGLSKEAN 356
Cdd:PRK15339 264 GDIKIIAYPDTNSLLVKGTAEQVHFIEMLVKALDVAKRHVELSLWIIDLDKSDLEQLGVNW--SGSI--TIGDKLGVSLN 339

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445939235 357 iinsngqvNPNINTLSGfslgflkagsEQIIGILSANQGNENFNVLSAPQVLTVDNQEAeisvgqdvpVRTQSRNAGTG- 435
Cdd:PRK15339 340 --------QSSISTLDG----------SRFIAAVMALEQKKKANVVSRPVVLTQENIPA---------IFDNNRTFYTKl 392

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445939235 436 -GTNAVTVDNYEYrptGIKLKFTPHVNKNNKITLELfqeikNIAEialagGNPTFNRREIKTSIS--------------- 499
Cdd:PRK15339 393 vGERNVALEHVTY---GTMISVLPRFSADGQIEMSL-----DIED-----GNEKTPQSDTTTSVDalpevgrtlistiar 459

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 445939235 500 IENTQSIVIGGLISNDKQKRIIKIPFLGDIPYLGHLFKRTTEKIKKTNLMVFITPHILDSRETAD 564
Cdd:PRK15339 460 VPQGKSLLIGGYTRDANTDEVQSIPFLGSLPLIGSLFRYSSKNKSNIVRVFLIEPREIVEPLTPD 524
Secretin_N pfam03958
Bacterial type II/III secretion system short domain; This is a short, often repeated, domain ...
 157-214 1.06e-07

Bacterial type II/III secretion system short domain; This is a short, often repeated, domain found in bacterial type II/III secretory system proteins. All previous NolW-like domains fall into this family.


Pssm-ID: 461109 [Multi-domain]  Cd Length: 68  Bit Score: 49.14  E-value: 1.06e-07
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 445939235  157 TQVIPIENVKPEELEPILKRL------TSPNTDVIVYRNTNTIVLSGSAADINKLLVLVSEFDV 214
Cdd:pfam03958   1 TRVIPLKYASAEDLASALRSLlggsglLSKRGSVVADPRTNSLIVSGPPEYVELVRQLIKQLDV 64
Secretin_N pfam03958
Bacterial type II/III secretion system short domain; This is a short, often repeated, domain ...
 230-315 1.88e-05

Bacterial type II/III secretion system short domain; This is a short, often repeated, domain found in bacterial type II/III secretory system proteins. All previous NolW-like domains fall into this family.


Pssm-ID: 461109 [Multi-domain]  Cd Length: 68  Bit Score: 42.59  E-value: 1.88e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 445939235  230 IHIYTLEYSEAEKIAATLvkldNPVIQSEDLGSERkppppgqpmpkvdkIKAVGHKESNSVIVTATNAEWAEIRKIIKVL 309
Cdd:pfam03958   1 TRVIPLKYASAEDLASAL----RSLLGGSGLLSKR--------------GSVVADPRTNSLIVSGPPEYVELVRQLIKQL 62


                  ....*.
gi 445939235  310 DSARKQ 315
Cdd:pfam03958  63 DVPRAQ 68
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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