|
Name |
Accession |
Description |
Interval |
E-value |
| NtrB |
COG3852 |
Signal transduction histidine kinase NtrB, nitrogen specific [Signal transduction mechanisms]; |
5-361 |
5.53e-155 |
|
Signal transduction histidine kinase NtrB, nitrogen specific [Signal transduction mechanisms];
Pssm-ID: 443061 [Multi-domain] Cd Length: 361 Bit Score: 439.67 E-value: 5.53e-155
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 5 ALHRLLLDNLTTATLLLNSKLCLEYMNPAAEMLLAVSGQRSHGQFISDLFTESPEALSSLRQAVEQAHPFNKREAVLTSV 84
Cdd:COG3852 7 ELLRAILDSLPDAVIVLDADGRITYVNPAAERLLGLSAEELLGRPLAELFPEDSPLRELLERALAEGQPVTEREVTLRRK 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 85 TGQTLTVDYAVTPLF-SKGETLLLLEVHPRDRLLRITKEEAQLSKQETTKLLVRGLAHEIKNPLGGIRGAAQLLSRELPN 163
Cdd:COG3852 87 DGEERPVDVSVSPLRdAEGEGGVLLVLRDITERKRLERELRRAEKLAAVGELAAGLAHEIRNPLTGIRGAAQLLERELPD 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 164 EELKDYTNVIIEEADRLRNLVDRMLGSNK--LPSLAMTNVHEVLERVANLIEAECQGGITLVRDYDPSIPDLLIDREQMI 241
Cdd:COG3852 167 DELREYTQLIIEEADRLNNLVDRLLSFSRprPPEREPVNLHEVLERVLELLRAEAPKNIRIVRDYDPSLPEVLGDPDQLI 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 242 QAVLNIVRNAMQAIAGQkhdmglGRISLRTRTLRQFTIGHTRHRLVVKVEIIDNGPGIPPELQETIFYPMVSGRADGTGL 321
Cdd:COG3852 247 QVLLNLVRNAAEAMPEG------GTITIRTRVERQVTLGGLRPRLYVRIEVIDNGPGIPEEILDRIFEPFFTTKEKGTGL 320
|
330 340 350 360
....*....|....*....|....*....|....*....|.
gi 2490585947 322 GLAITQNIISQHQGLIECESHVG-HTVFSIFLPLEQGAPTP 361
Cdd:COG3852 321 GLAIVQKIVEQHGGTIEVESEPGkGTTFRIYLPLEQAEEEP 361
|
|
| glnL |
PRK11073 |
nitrogen regulation protein NR(II); |
10-354 |
1.06e-140 |
|
nitrogen regulation protein NR(II);
Pssm-ID: 182947 [Multi-domain] Cd Length: 348 Bit Score: 402.92 E-value: 1.06e-140
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 10 LLDNLTTATLLLNSKLCLEYMNPAAEMLLAVSGQRSHGQFISDLFTESPEALSSLRQAVEQAHPFNKREAVLTsVTGQTL 89
Cdd:PRK11073 12 ILNSLINSILLLDDDLAIHYANPAAQQLLAQSSRKLFGTPLPELLSYFSLNIELMRESLQAGQGFTDNEVTLV-IDGRSH 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 90 TVDYAVTPLfskGETLLLLEVHPRDRLLRITKEEAQLSKQETTKLLVRGLAHEIKNPLGGIRGAAQLLSRELPNEELKDY 169
Cdd:PRK11073 91 ILSLTAQRL---PEGMILLEMAPMDNQRRLSQEQLQHAQQVAARDLVRGLAHEIKNPLGGLRGAAQLLSKALPDPALTEY 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 170 TNVIIEEADRLRNLVDRMLGSNKLPSLAMTNVHEVLERVANLIEAECQGGITLVRDYDPSIPDLLIDREQMIQAVLNIVR 249
Cdd:PRK11073 168 TKVIIEQADRLRNLVDRLLGPQRPGTHVTESIHKVAERVVQLVSLELPDNVRLIRDYDPSLPELAHDPDQIEQVLLNIVR 247
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 250 NAMQAIaGQKHdmglGRISLRTRTLRQFTIGHTRHRLVVKVEIIDNGPGIPPELQETIFYPMVSGRADGTGLGLAITQNI 329
Cdd:PRK11073 248 NALQAL-GPEG----GTITLRTRTAFQLTLHGERYRLAARIDIEDNGPGIPPHLQDTLFYPMVSGREGGTGLGLSIARNL 322
|
330 340
....*....|....*....|....*
gi 2490585947 330 ISQHQGLIECESHVGHTVFSIFLPL 354
Cdd:PRK11073 323 IDQHSGKIEFTSWPGHTEFSVYLPI 347
|
|
| NtrY |
COG5000 |
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism ... |
4-359 |
5.03e-72 |
|
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism regulation [Signal transduction mechanisms];
Pssm-ID: 444024 [Multi-domain] Cd Length: 422 Bit Score: 230.23 E-value: 5.03e-72
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 4 DALHRLL---LDNLTTATLLLNSKLCLEYMNPAAEMLLAVSGQRSHGQFISDLFTESPealssLRQAVEQAHPFNKREAV 80
Cdd:COG5000 86 EERRRYLetiLENLPAGVIVLDADGRITLANPAAERLLGIPLEELIGKPLEELLPELD-----LAELLREALERGWQEEI 160
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 81 LTSVTGQtLTVDYAVTPLFSKGeTLLLLEvhprdrllRITkEEAQLSKQETTKLLVRGLAHEIKNPLGGIRGAAQLLSRE 160
Cdd:COG5000 161 ELTRDGR-RTLLVRASPLRDDG-YVIVFD--------DIT-ELLRAERLAAWGELARRIAHEIKNPLTPIQLSAERLRRK 229
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 161 LP------NEELKDYTNVIIEEADRLRNLVDRMLGSNKLPSLAMT--NVHEVLERVANLIEAECQG-GITLVRDYDPSIP 231
Cdd:COG5000 230 LAdkleedREDLERALDTIIRQVDRLKRIVDEFLDFARLPEPQLEpvDLNELLREVLALYEPALKEkDIRLELDLDPDLP 309
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 232 DLLIDREQMIQAVLNIVRNAMQAIAGQkhdmglGRISLRTRTLRQFtightrhrlvVKVEIIDNGPGIPPELQETIFYPM 311
Cdd:COG5000 310 EVLADRDQLEQVLINLLKNAIEAIEEG------GEIEVSTRREDGR----------VRIEVSDNGPGIPEEVLERIFEPF 373
|
330 340 350 360
....*....|....*....|....*....|....*....|....*....
gi 2490585947 312 VSGRADGTGLGLAITQNIISQHQGLIECESHVGH-TVFSIFLPLEQGAP 359
Cdd:COG5000 374 FTTKPKGTGLGLAIVKKIVEEHGGTIELESRPGGgTTFTIRLPLAEEAE 422
|
|
| HATPase_Glnl-NtrB-like |
cd16918 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
240-353 |
5.14e-62 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli GlnL (synonyms NtrB and NRII); This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs), similar to Escherichia coli GlnL/NtrB/NRII HK of the two-component regulatory system (TCS) GlnL/GlnG (NtrB-NtrC, or NRII-NRI), which regulates the transcription of genes encoding metabolic enzymes and permeases in response to carbon and nitrogen status in E. coli and related bacteria. Also included in this family are Rhodobacter capsulatus NtrB, Azospirillum brasilense NtrB, Vibrio alginolyticus NtrB, Rhizobium leguminosarum biovar phaseoli NtrB, and Herbaspirillum seropedicae NtrB. Escherichia coli GlnL/NtrB/NRII is both a kinase and a phosphatase, catalyzing the phosphorylation and dephosphorylation of GlnG/NtrC/NRI. The kinase and phosphatase activities of GlnL/NtrB/NRII are regulated by the PII signal transduction protein, which on binding to GlnL/NtrB/NRII, inhibits the kinase activity of GlnL/NtrB/NRII and activates the GlnL/NtrB/NRII phosphatase activity. Proteins having this HATPase domain also have a histidine kinase dimerization and phosphoacceptor domain (HisKA); some also contain PAS sensor domain(s).
Pssm-ID: 340395 [Multi-domain] Cd Length: 109 Bit Score: 193.77 E-value: 5.14e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 240 MIQAVLNIVRNAMQAIAGqkhdmGLGRISLRTRTLRQFTIGHTRHRLVVKVEIIDNGPGIPPELQETIFYPMVSGRADGT 319
Cdd:cd16918 1 LIQVFLNLVRNAAQALAG-----SGGEIILRTRTQRQVTLGHPRHRLALRVSVIDNGPGIPPDLQDTIFYPMVSGRENGT 75
|
90 100 110
....*....|....*....|....*....|....
gi 2490585947 320 GLGLAITQNIISQHQGLIECESHVGHTVFSIFLP 353
Cdd:cd16918 76 GLGLAIAQNIVSQHGGVIECDSQPGHTVFSVSLP 109
|
|
| COG4191 |
COG4191 |
Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal ... |
34-354 |
1.09e-54 |
|
Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal transduction mechanisms];
Pssm-ID: 443345 [Multi-domain] Cd Length: 361 Bit Score: 183.46 E-value: 1.09e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 34 AEMLLAVSGQRSHGQFISDLFTESPEALSSLRQAVEQAHPFNKREAVLTSVTGQTLTVDYAVTPLFSKGETLLLLEVHPR 113
Cdd:COG4191 41 ALLLALLALLLLLLLLLLLLLLELLLLLLALLGGLLRLLLLLGLLLLLLLEALLLLLLAALDAEENAELEELERDITELE 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 114 DRLLRITKEEAQLSKQEttKL-----LVRGLAHEIKNPLGGIRGAAQLLSRELPN----EELKDYTNVIIEEADRLRNLV 184
Cdd:COG4191 121 RAEEELRELQEQLVQSE--KLaalgeLAAGIAHEINNPLAAILGNAELLRRRLEDepdpEELREALERILEGAERAAEIV 198
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 185 DRMLGSNKLPSLAM--TNVHEVLERVANLIEAEC-QGGITLVRDYDPSIPDLLIDREQMIQAVLNIVRNAMQAIAGQKHd 261
Cdd:COG4191 199 RSLRAFSRRDEEERepVDLNELIDEALELLRPRLkARGIEVELDLPPDLPPVLGDPGQLEQVLLNLLINAIDAMEEGEG- 277
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 262 mglGRISLRTRTLRQFtightrhrlvVKVEIIDNGPGIPPELQETIFYPMVS--GRADGTGLGLAITQNIISQHQGLIEC 339
Cdd:COG4191 278 ---GRITISTRREGDY----------VVISVRDNGPGIPPEVLERIFEPFFTtkPVGKGTGLGLSISYGIVEKHGGRIEV 344
|
330
....*....|....*.
gi 2490585947 340 ESHVGH-TVFSIFLPL 354
Cdd:COG4191 345 ESEPGGgTTFTITLPL 360
|
|
| PRK11360 |
PRK11360 |
two-component system sensor histidine kinase AtoS; |
30-358 |
2.81e-54 |
|
two-component system sensor histidine kinase AtoS;
Pssm-ID: 236901 [Multi-domain] Cd Length: 607 Bit Score: 187.87 E-value: 2.81e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 30 MNPAAEMLLAVSGQRSHGQFISDLFTESPEALSSLRQAVE--QAHpfnKREAVLTSVTGQTLTVDYAVTPLFSKGETLLL 107
Cdd:PRK11360 287 MNPAAEVITGLQRHELVGKPYSELFPPNTPFASPLLDTLEhgTEH---VDLEISFPGRDRTIELSVSTSLLHNTHGEMIG 363
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 108 LEVHPRDRLLRITKEEaQLSKQE---TTKLLVRGLAHEIKNPLGGIRGAAQLLSRELPNEELKDYTNVIIEEADRLRNLV 184
Cdd:PRK11360 364 ALVIFSDLTERKRLQR-RVARQErlaALGELVAGVAHEIRNPLTAIRGYVQIWRQQTSDPPSQEYLSVVLREVDRLNKVI 442
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 185 DRML--GSNKLPSLAMTNVHEVLERVANLI-EAECQGGITLVRDYDPSIPDLLIDREQMIQAVLNIVRNAMQAIAGqkhd 261
Cdd:PRK11360 443 DQLLefSRPRESQWQPVSLNALVEEVLQLFqTAGVQARVDFETELDNELPPIWADPELLKQVLLNILINAVQAISA---- 518
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 262 mgLGRISLRTRtlrQFTIGHtrhrlvVKVEIIDNGPGIPPELQETIFYPMVSGRADGTGLGLAITQNIISQHQGLIECES 341
Cdd:PRK11360 519 --RGKIRIRTW---QYSDGQ------VAVSIEDNGCGIDPELLKKIFDPFFTTKAKGTGLGLALSQRIINAHGGDIEVES 587
|
330
....*....|....*...
gi 2490585947 342 HVGH-TVFSIFLPLEQGA 358
Cdd:PRK11360 588 EPGVgTTFTLYLPINPQG 605
|
|
| KinC |
COG5807 |
Sporulation sensor histidine kinase C [Cell cycle control, cell division, chromosome ... |
10-354 |
1.20e-48 |
|
Sporulation sensor histidine kinase C [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444509 [Multi-domain] Cd Length: 358 Bit Score: 167.66 E-value: 1.20e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 10 LLDNLTTATLLLNSKLCLEYMNPAAEMLLAVSgqrsHGQFISDLFTESPEALSSLRQAVEQahPFNKREAVLTSVTGqtl 89
Cdd:COG5807 32 LFDSILEFVFFIDSKGEILECNDFAEDLYGLS----QNEYIGKTFVEEKCILKDEQLYNKE--AFDRIEISYLTKNG--- 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 90 TVDYAVTPLFSKGETLLLLEVHPRDRLLRITKEEAQLSKQETTKL--LVRGLAHEIKNPLGGIRGAAQLLSRELPNEELK 167
Cdd:COG5807 103 EFDEIIYPIYYKDGVILGLITVYRDITKRKEAEDKLLRSEKLSVAgeLAAGIAHEIRNPLTSIKGFLQLLQESREDSERE 182
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 168 DYTNVIIEEADRLRNLVDRML--GSNKLPSLAMTNVHEVLERVANLIEAEC-QGGITLVRDYDPSIPDLLIDREQMIQAV 244
Cdd:COG5807 183 EYFNIIISEIDRINTIITELLvlSKPKKFNFKKLNLNDVLEDVIALLSTEAiLKNISIKYDLADDEPVINGDKNQLKQVF 262
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 245 LNIVRNAMQAIAGQkhdmglGRISLRTRTLRQFtightrhrlvVKVEIIDNGPGIPPELQETIFYPMVSGRADGTGLGLA 324
Cdd:COG5807 263 INLIKNAIEAMETG------GNITIKTYVEGDF----------VVISVKDEGIGIPEEVLEKIGEPFFTTKEEGTGLGLS 326
|
330 340 350
....*....|....*....|....*....|.
gi 2490585947 325 ITQNIISQHQGLIECESHVGH-TVFSIFLPL 354
Cdd:COG5807 327 ICKKIIEEHNGTIEVESKPGKgTTFTIYLPL 357
|
|
| BaeS |
COG0642 |
Signal transduction histidine kinase [Signal transduction mechanisms]; |
37-355 |
8.63e-47 |
|
Signal transduction histidine kinase [Signal transduction mechanisms];
Pssm-ID: 440407 [Multi-domain] Cd Length: 328 Bit Score: 162.00 E-value: 8.63e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 37 LLAVSGQRSHGQFISDLFTESPEALSSLRQAVEQAHPFNKREAVLTSVTGQTLTVDYAVTPLFSKGETLLLLEVHPRDRL 116
Cdd:COG0642 14 LLLLLLLALLLLLLLLLLLALLLLLALLLLLLLLLLLLLLLALALLALLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLL 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 117 LRITKEEAQLSKQETTK-LLVRGLAHEIKNPLGGIRGAAQLLSRElPNEELKDYTNVIIEEADRLRNLVDRMLGSNKLPS 195
Cdd:COG0642 94 LLLLALLLLLEEANEAKsRFLANVSHELRTPLTAIRGYLELLLEE-LDEEQREYLETILRSADRLLRLINDLLDLSRLEA 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 196 LAMT------NVHEVLERVANLIEAECQG-GITLVRDYDPSIPDLLIDREQMIQAVLNIVRNAMQAIAGQkhdmglGRIS 268
Cdd:COG0642 173 GKLElepepvDLAELLEEVVELFRPLAEEkGIELELDLPDDLPTVRGDPDRLRQVLLNLLSNAIKYTPEG------GTVT 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 269 LRTRtlrqftightRHRLVVKVEIIDNGPGIPPELQETIFYPMV----SGRADGTGLGLAITQNIISQHQGLIECESHVG 344
Cdd:COG0642 247 VSVR----------REGDRVRISVEDTGPGIPPEDLERIFEPFFrtdpSRRGGGTGLGLAIVKRIVELHGGTIEVESEPG 316
|
330
....*....|..
gi 2490585947 345 H-TVFSIFLPLE 355
Cdd:COG0642 317 KgTTFTVTLPLA 328
|
|
| KinE |
COG5809 |
Sporulation sensor histidine kinase E [Cell cycle control, cell division, chromosome ... |
7-359 |
1.36e-46 |
|
Sporulation sensor histidine kinase E [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444511 [Multi-domain] Cd Length: 489 Bit Score: 165.15 E-value: 1.36e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 7 HRLLLDNLTTATLLLNSKLCLEYMNPAAEMLLAVSGQRSHGQFISDLFTESP--EALSSLRQAVEQAHPFNKrEAVLTSV 84
Cdd:COG5809 143 FRLIFNHSPDGIIVTDLDGRIIYANPAACKLLGISIEELIGKSILELIHSDDqeNVAAFISQLLKDGGIAQG-EVRFWTK 221
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 85 TGQTLTVDYAVTPLFSKGETLLLLEVHpRDRLLRITKEEaQLSKQETTKLLVR---GLAHEIKNPLGGIRGAAQLLsREL 161
Cdd:COG5809 222 DGRWRLLEASGAPIKKNGEVDGIVIIF-RDITERKKLEE-LLRKSEKLSVVGElaaGIAHEIRNPLTSLKGFIQLL-KDT 298
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 162 PNEELKDYTNVIIEEADRLRNLVDR--MLGSNKLPSLAMTNVHEVLERVANLIEAEC-QGGITLVRDYDPSIPDLLIDRE 238
Cdd:COG5809 299 IDEEQKTYLDIMLSELDRIESIISEflVLAKPQAIKYEPKDLNTLIEEVIPLLQPQAlLKNVQIELELEDDIPDILGDEN 378
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 239 QMIQAVLNIVRNAMQAIAGQkhdmglGRISLRTRtlrqftigHTRHRLVVkVEIIDNGPGIPPELQETIFYPMVSGRADG 318
Cdd:COG5809 379 QLKQVFINLLKNAIEAMPEG------GNITIETK--------AEDDDKVV-ISVTDEGCGIPEERLKKLGEPFYTTKEKG 443
|
330 340 350 360
....*....|....*....|....*....|....*....|..
gi 2490585947 319 TGLGLAITQNIISQHQGLIECESHVGH-TVFSIFLPLEQGAP 359
Cdd:COG5809 444 TGLGLMVSYKIIEEHGGKITVESEVGKgTTFSITLPIKLSEQ 485
|
|
| KdpD |
COG2205 |
K+-sensing histidine kinase KdpD [Signal transduction mechanisms]; |
118-356 |
1.97e-45 |
|
K+-sensing histidine kinase KdpD [Signal transduction mechanisms];
Pssm-ID: 441807 [Multi-domain] Cd Length: 239 Bit Score: 155.45 E-value: 1.97e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 118 RITKEEAQLSKQETTK-LLVRGLAHEIKNPLGGIRGAAQLLSR--ELPNEELKDYTNVIIEEADRLRNLVDRMLGSNKL- 193
Cdd:COG2205 1 ELEEALEELEELERLKsEFLANVSHELRTPLTSILGAAELLLDeeDLSPEERRELLEIIRESAERLLRLIEDLLDLSRLe 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 194 -----PSLAMTNVHEVLERVANLIEAECQG-GITLVRDYDPSIPDLLIDREQMIQAVLNIVRNAMqaiagqKHDMGLGRI 267
Cdd:COG2205 81 sgklsLELEPVDLAELLEEAVEELRPLAEEkGIRLELDLPPELPLVYADPELLEQVLANLLDNAI------KYSPPGGTI 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 268 SLRTRTLRQFtightrhrlvVKVEIIDNGPGIPPELQETIFYPMVSG----RADGTGLGLAITQNIISQHQGLIECESHV 343
Cdd:COG2205 155 TISARREGDG----------VRISVSDNGPGIPEEELERIFERFYRGdnsrGEGGTGLGLAIVKRIVEAHGGTIWVESEP 224
|
250
....*....|....
gi 2490585947 344 GH-TVFSIFLPLEQ 356
Cdd:COG2205 225 GGgTTFTVTLPLAE 238
|
|
| WalK |
COG5002 |
Sensor histidine kinase WalK [Signal transduction mechanisms]; |
8-356 |
1.01e-40 |
|
Sensor histidine kinase WalK [Signal transduction mechanisms];
Pssm-ID: 444026 [Multi-domain] Cd Length: 390 Bit Score: 147.39 E-value: 1.01e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 8 RLLLDNLTTATLLLNSKLCLEYMNPAAEMLLAVSGQRSHGQFISDLFTESPEALSSLRQAVEQAHPFNKREAVLTSVTGQ 87
Cdd:COG5002 40 LLLLLLLLLLLLLALLLLLLLLLLLLLALLLLLLLLLLLLALALLLLALLLLLLLLLLLLALLILLLLLALLILLAALLL 119
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 88 TLTVDYAVTPLFSKGETLLLLEVHPRDRLLRITKEEAQLSKQETTK-LLVRGLAHEIKNPLGGIRGAAQLLSRE--LPNE 164
Cdd:COG5002 120 LLSELLLLLLLLGRLSLRLSALLLGLLLLAAVERDITELERLEQMRrEFVANVSHELRTPLTSIRGYLELLLDGaaDDPE 199
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 165 ELKDYTNVIIEEADRLRNLVDRML-------GSNKLpSLAMTNVHEVLERVANLIEAEC-QGGITLVRDYDPSIPDLLID 236
Cdd:COG5002 200 ERREYLEIILEEAERLSRLVNDLLdlsrlesGELKL-EKEPVDLAELLEEVVEELRPLAeEKGIELELDLPEDPLLVLGD 278
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 237 REQMIQAVLNIVRNAMqaiagqKHDMGLGRISLRTRTLRQFtightrhrlvVKVEIIDNGPGIPPELQETI---FYpmvs 313
Cdd:COG5002 279 PDRLEQVLTNLLDNAI------KYTPEGGTITVSLREEDDQ----------VRISVRDTGIGIPEEDLPRIferFY---- 338
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|..
gi 2490585947 314 gRAD--------GTGLGLAITQNIISQHQGLIECESHVGH-TVFSIFLPLEQ 356
Cdd:COG5002 339 -RVDksrsretgGTGLGLAIVKHIVEAHGGRIWVESEPGKgTTFTITLPLAR 389
|
|
| KinA |
COG5805 |
Sporulation sensor histidine kinase A (Stage II sporulation protein SpoIIF/SpoIIJ) [Cell cycle ... |
2-354 |
6.70e-39 |
|
Sporulation sensor histidine kinase A (Stage II sporulation protein SpoIIF/SpoIIJ) [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444507 [Multi-domain] Cd Length: 496 Bit Score: 144.49 E-value: 6.70e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 2 INDALHRLLLDNLTTATLLLNSKLCLEYMNPAAEMLLAVSGQRSHGQFISDLFTES-PEALSSLRQAVEQAhpFNKREAV 80
Cdd:COG5805 154 EQEERLQTLIENSPDLICVIDTDGRILFINESIERLFGAPREELIGKNLLELLHPCdKEEFKERIESITEV--WQEFIIE 231
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 81 LTSVT--GQTLTVDYAVTPLFSKGETLLLLEVHPRDrllrITKeeaqlsKQETTKLLVR------------GLAHEIKNP 146
Cdd:COG5805 232 REIITkdGRIRYFEAVIVPLIDTDGSVKGILVILRD----ITE------KKEAEELMARseklsiagqlaaGIAHEIRNP 301
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 147 LGGIRGAAQLLSRELpnEELKDYTNVIIEEADRLRNLVDRMLGSNK--LPSLAMTNVHEVLERVANLIEAECQ-GGITLV 223
Cdd:COG5805 302 LTSIKGFLQLLQPGI--EDKEEYFDIMLSELDRIESIISEFLALAKpqAVNKEKENINELIQDVVTLLETEAIlHNIQIR 379
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 224 RDYDPSIPDLLIDREQMIQAVLNIVRNAMQAIagqkhDMGlGRISLRTRTLRQFtightrhrlvVKVEIIDNGPGIPPEL 303
Cdd:COG5805 380 LELLDEDPFIYCDENQIKQVFINLIKNAIEAM-----PNG-GTITIHTEEEDNS----------VIIRVIDEGIGIPEER 443
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|..
gi 2490585947 304 QETIFYPMVSGRADGTGLGLAITQNIISQHQGLIECESHVGH-TVFSIFLPL 354
Cdd:COG5805 444 LKKLGEPFFTTKEKGTGLGLMVSYKIIENHNGTIDIDSKVGKgTTFTITLPL 495
|
|
| KinD |
COG5808 |
Sporulation sensor histidine kinase D [Cell cycle control, cell division, chromosome ... |
105-356 |
8.44e-36 |
|
Sporulation sensor histidine kinase D [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444510 [Multi-domain] Cd Length: 454 Bit Score: 135.26 E-value: 8.44e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 105 LLLLEVHPRDRLLRITKEEAQLSKQETTKLLVRGLAHEIKNPLGGIRGAAQLLSRELPNEELKDYTNVIIEEADRLRNLV 184
Cdd:COG5808 214 LLQYNLLKRKTLLERVIQEINTQKLELIGTFAASTAHEIRNPLTSIKGFIQLLQEKYPELEDQKYFDIIQEEIQRINQIV 293
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 185 DRMLGSNKLPSLAMT--NVHEVLERVANLIEAECQG-GITLVR-DYDPSIPdLLIDREQMIQAVLNIVRNAMQAIAGQkh 260
Cdd:COG5808 294 SEFLVLGKPTAKKLEldDLNELIEEILSIIDSEANLkNIRVEKqSLDEPLH-IKCDKDRIKQVLLNLIKNAIEAMKEG-- 370
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 261 dmglGRISLrtrtlrqfTIGHTRHRLVVkvEIIDNGPGIPPELQETIFYPMVSGRADGTGLGLAITQNIISQHQGLIECE 340
Cdd:COG5808 371 ----GKLTI--------SIENDDEKAVI--EVIDNGEGIPEDIIDEIFEPFVTTKEGGTGLGLSVCKRIVEMHGGEIDIE 436
|
250
....*....|....*..
gi 2490585947 341 SHVGH-TVFSIFLPLEQ 356
Cdd:COG5808 437 SEEGKgTTFTIRLPLKK 453
|
|
| PRK10364 |
PRK10364 |
two-component system sensor histidine kinase ZraS; |
135-354 |
5.51e-34 |
|
two-component system sensor histidine kinase ZraS;
Pssm-ID: 236674 [Multi-domain] Cd Length: 457 Bit Score: 130.29 E-value: 5.51e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 135 LVRGLAHEIKNPLGGIRGAAQLLSRELPNE-ELKDYTNVIIEEADRLRNLVDRMLGSNKlPS---LAMTNVHEVLERVAN 210
Cdd:PRK10364 240 LAAGVAHEIRNPLSSIKGLAKYFAERAPAGgEAHQLAQVMAKEADRLNRVVSELLELVK-PThlaLQAVDLNDLINHSLQ 318
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 211 LIEAECQG-GITLVRDYDPSIPDLLIDREQMIQAVLNIVRNAMQAIAGQkhdmglGRIslrtrtlrqfTIGHTRHRLVVK 289
Cdd:PRK10364 319 LVSQDANSrEIQLRFTANDTLPEIQADPDRLTQVLLNLYLNAIQAIGQH------GVI----------SVTASESGAGVK 382
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2490585947 290 VEIIDNGPGIPPELQETIFYPMVSGRADGTGLGLAITQNIISQHQGLIECESHVGH-TVFSIFLPL 354
Cdd:PRK10364 383 ISVTDSGKGIAADQLEAIFTPYFTTKAEGTGLGLAVVHNIVEQHGGTIQVASQEGKgATFTLWLPV 448
|
|
| PRK13837 |
PRK13837 |
two-component system VirA-like sensor kinase; |
130-359 |
2.28e-28 |
|
two-component system VirA-like sensor kinase;
Pssm-ID: 237526 [Multi-domain] Cd Length: 828 Bit Score: 116.32 E-value: 2.28e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 130 ETTKLLVRGLAHEIKNPLGGIRGAAQL-LSRELPNEELKDYTNVIIEEADRLRNLVDRMLG-SNKLPSLAMT-NVHEVLE 206
Cdd:PRK13837 448 EAVGTLASGIAHNFNNILGAILGYAEMaLNKLARHSRAARYIDEIISAGARARLIIDQILAfGRKGERNTKPfDLSELVT 527
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 207 RVANLIEAECQGGITLVRDYDPSIPDLLIDREQMIQAVLNIVRNAMQAI-AGQKHDMGLGRISLRT-RTLRQFTIGhTRH 284
Cdd:PRK13837 528 EIAPLLRVSLPPGVELDFDQDQEPAVVEGNPAELQQVLMNLCSNAAQAMdGAGRVDISLSRAKLRApKVLSHGVLP-PGR 606
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2490585947 285 RLVVKVEiiDNGPGIPPELQETIFYPMVSGRADGTGLGLAITQNIISQHQGLIECESHVGH-TVFSIFLPLEQGAP 359
Cdd:PRK13837 607 YVLLRVS--DTGAGIDEAVLPHIFEPFFTTRAGGTGLGLATVHGIVSAHAGYIDVQSTVGRgTRFDVYLPPSSKVP 680
|
|
| COG4251 |
COG4251 |
Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal ... |
1-357 |
3.98e-27 |
|
Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal transduction mechanisms];
Pssm-ID: 443393 [Multi-domain] Cd Length: 503 Bit Score: 111.80 E-value: 3.98e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 1 MINDALHRLLLDNLTTATLLLNSKLCLEYMNPAAEMLLAVSGQRSHGQFISDLFTESPEALSSLRQAVEQAHPFNKREAV 80
Cdd:COG4251 141 ALLRLALALLLLLLLLLLLLLLLLALILALLLAALAELELLLLLLLVLLLLLLLLLLLLLLLLRLLLELLLLLEAELLLS 220
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 81 LTSVTGQTLTVDYAVTPLFSKGETLLLLEVHPRDRLLRITKEEAQLSKQETTKLLVR----------GLAHEIKNPLGGI 150
Cdd:COG4251 221 LGGGLGLLLLLLLLLVLLLLLILLLLLLILVLELLELRLELEELEEELEERTAELERsneeleqfayVASHDLREPLRKI 300
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 151 RGAAQLLSREL---PNEELKDYTNVIIEEADRLRNLVDRML-----GSNKLPsLAMTNVHEVLERV-ANLIEAECQGGIT 221
Cdd:COG4251 301 SGFSQLLEEDYgdkLDEEGREYLERIRDAAERMQALIDDLLaysrvGRQELE-FEPVDLNELLEEVlEDLEPRIEERGAE 379
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 222 LVRDYDPSIpdlLIDREQMIQAVLNIVRNAMQAIAGQKHdmglGRIslrtrtlrqfTIGHTRHRLVVKVEIIDNGPGIPP 301
Cdd:COG4251 380 IEVGPLPTV---RGDPTLLRQVFQNLISNAIKYSRPGEP----PRI----------EIGAEREGGEWVFSVRDNGIGIDP 442
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2490585947 302 ELQETIFYPM--VSGRAD--GTGLGLAITQNIISQHQGLIECESHVGH-TVFSIFLPLEQG 357
Cdd:COG4251 443 EYAEKIFEIFqrLHSRDEyeGTGIGLAIVKKIVERHGGRIWVESEPGEgATFYFTLPKAPA 503
|
|
| KinB |
COG5806 |
Sporulation sensor histidine kinase B [Cell cycle control, cell division, chromosome ... |
80-354 |
3.05e-26 |
|
Sporulation sensor histidine kinase B [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444508 [Multi-domain] Cd Length: 412 Bit Score: 108.42 E-value: 3.05e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 80 VLTSVTGQTL--TVDYAVTPLFSKGETLLLLEVHPRDRLLRitKEEAQLSKQETTKLLVRGLAHEIKNPLGGIRGAAQLL 157
Cdd:COG5806 149 IFIADISELLdfILYFIIIQLLAMLIAVYLIENLIENILLR--KELQRAEKLEVVSELAASIAHEVRNPLTVVRGFIQLL 226
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 158 -SRELPNEELKDYTNVIIEEADRLRNLVDRMLGSNK--LPSLAMTNVHEVLERVANLIEAECQG-GITLVRDYDPSIpDL 233
Cdd:COG5806 227 qEPELSDEKRKQYIRIALEELDRAEAIITDYLTFAKpqPEKLEKIDVSEELEHVIDVLSPYANMnNVEIQTELEPGL-YI 305
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 234 LIDREQMIQAVLNIVRNAMQAIAgqkhDMGLGRISLRtrtlrqftightRHRLVVKVEIIDNGPGIPPELQETIFYPMVS 313
Cdd:COG5806 306 EGDRQKLQQCLINIIKNGIEAMP----NGGTLTIDVS------------IDKNKVIISIKDTGVGMTKEQLERLGEPYFS 369
|
250 260 270 280
....*....|....*....|....*....|....*....|..
gi 2490585947 314 GRADGTGLGLAITQNIISQHQGLIECESHVGH-TVFSIFLPL 354
Cdd:COG5806 370 TKEKGTGLGTMVSYRIIEAMNGTIRVESEVGKgTTFTITLPL 411
|
|
| CitA |
COG3290 |
Sensor histidine kinase DipB regulating citrate/malate metabolism [Signal transduction ... |
7-355 |
1.57e-25 |
|
Sensor histidine kinase DipB regulating citrate/malate metabolism [Signal transduction mechanisms];
Pssm-ID: 442519 [Multi-domain] Cd Length: 389 Bit Score: 106.09 E-value: 1.57e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 7 HRLLLDNLTTATLLLNSKLCLEYMNPAAEMLLavsGQRSHGQFISDLFTESPEAlsslrQAVEQAHPFNKREAVLTSVtg 86
Cdd:COG3290 86 REAVLESIREGVIAVDRDGRITLINDAARRLL---GLDAIGRPIDEVLAEVLET-----GERDEEILLNGRVLVVNRV-- 155
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 87 qtltvdyavtPLFSKGETLLLLeVHPRDRLlRITKEEAQLSKQETTKLLVRGLAHEIKNPLGGIRGAAQLLSrelpNEEL 166
Cdd:COG3290 156 ----------PIRDDGRVVGAV-ATFRDRT-ELERLEEELEGVKELAEALRAQRHDFRNHLHTISGLLQLGE----YDEA 219
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 167 KDYtnvIIEEADRLRNLVDRMLGSNKLPSLAmtnvhEVLERVANLIEAEcqgGITLVRDYDPSIPDLLIDREQMIQAVLN 246
Cdd:COG3290 220 LEY---IDEISEELQELIDSLLSRIGNPVLA-----ALLLGKAARARER---GIDLTIDIDSDLPDLPLSDTDLVTILGN 288
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 247 IVRNAMQAIAGQKHDMGlgRISLrtrtlrqfTIGHTRHRLVVKVEiiDNGPGIPPELQETIFYPMVS-GRADGTGLGLAI 325
Cdd:COG3290 289 LLDNAIEAVEKLPEEER--RVEL--------SIRDDGDELVIEVE--DSGPGIPEELLEKIFERGFStKLGEGRGLGLAL 356
|
330 340 350
....*....|....*....|....*....|.
gi 2490585947 326 TQNIISQHQGLIECESHVGH-TVFSIFLPLE 355
Cdd:COG3290 357 VKQIVEKYGGTIEVESEEGEgTVFTVRLPKE 387
|
|
| HATPase_AtoS-like |
cd16943 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
237-354 |
2.30e-24 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli K-12 AtoS; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs) such as Escherichia coli AtoS, an HK of the AtoS-AtoC TCS. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some have accessory domains such as HAMP or PAS sensor domains or CBS-pair domains.
Pssm-ID: 340419 [Multi-domain] Cd Length: 105 Bit Score: 95.57 E-value: 2.30e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 237 REQMIQAVLNIVRNAMQAIAGQkhdmglGRISLRTrtlrqftiGHTRHRlvVKVEIIDNGPGIPPELQETIFYPMVSGR- 315
Cdd:cd16943 1 PSQLNQVLLNLLVNAAQAMEGR------GRITIRT--------WAHVDQ--VLIEVEDTGSGIDPEILGRIFDPFFTTKp 64
|
90 100 110 120
....*....|....*....|....*....|....*....|.
gi 2490585947 316 -ADGTGLGLAITQNIISQHQGLIECESHVGH-TVFSIFLPL 354
Cdd:cd16943 65 vGEGTGLGLSLSYRIIQKHGGTIRVASVPGGgTRFTIILPI 105
|
|
| HATPase_c |
smart00387 |
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases. |
235-355 |
5.53e-24 |
|
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases.
Pssm-ID: 214643 [Multi-domain] Cd Length: 111 Bit Score: 95.02 E-value: 5.53e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 235 IDREQMIQAVLNIVRNAMqaiagqKHDMGLGRISLRTRtlrqftightRHRLVVKVEIIDNGPGIPPELQETIFYPMVSG 314
Cdd:smart00387 1 GDPDRLRQVLSNLLDNAI------KYTPEGGRITVTLE----------RDGDHVEITVEDNGPGIPPEDLEKIFEPFFRT 64
|
90 100 110 120
....*....|....*....|....*....|....*....|....*..
gi 2490585947 315 RAD-----GTGLGLAITQNIISQHQGLIECESHVGH-TVFSIFLPLE 355
Cdd:smart00387 65 DKRsrkigGTGLGLSIVKKLVELHGGEISVESEPGGgTTFTITLPLE 111
|
|
| PRK11100 |
PRK11100 |
sensory histidine kinase CreC; Provisional |
136-347 |
4.10e-22 |
|
sensory histidine kinase CreC; Provisional
Pssm-ID: 236846 [Multi-domain] Cd Length: 475 Bit Score: 97.22 E-value: 4.10e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 136 VRGLAHEIKNPLGGIRGAAQLLSRELPNEELKDYTNVIIEEADRLRNLVDRMLGSNKLPS------LAMTNVHEVLERVA 209
Cdd:PRK11100 260 VQTLTHELKSPLAAIRGAAELLQEDPPPEDRARFTGNILTQSARLQQLIDRLLELARLEQrqelevLEPVALAALLEELV 339
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 210 NLIEAECQG-GITLVRDYDPSipDLLIDREQMIQAVLNIVRNAMQ-AIAGqkhdmglGRISLRTRTLRQFtightrhrlv 287
Cdd:PRK11100 340 EAREAQAAAkGITLRLRPDDA--RVLGDPFLLRQALGNLLDNAIDfSPEG-------GTITLSAEVDGEQ---------- 400
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2490585947 288 VKVEIIDNGPGIPPELQETI---FY--PMVSGRADGTGLGLAITQNIISQHQGLIECESHVGHTV 347
Cdd:PRK11100 401 VALSVEDQGPGIPDYALPRIferFYslPRPANGRKSTGLGLAFVREVARLHGGEVTLRNRPEGGV 465
|
|
| HATPase |
cd00075 |
Histidine kinase-like ATPase domain; This superfamily includes the histidine kinase-like ... |
240-352 |
1.26e-19 |
|
Histidine kinase-like ATPase domain; This superfamily includes the histidine kinase-like ATPase (HATPase) domains of several ATP-binding proteins such as histidine kinase, DNA gyrase B, topoisomerases, heat shock protein 90 (HSP90), phytochrome-like ATPases and DNA mismatch repair proteins. Domains belonging to this superfamily are also referred to as GHKL (gyrase, heat-shock protein 90, histidine kinase, MutL) ATPase domains.
Pssm-ID: 340391 [Multi-domain] Cd Length: 102 Bit Score: 82.65 E-value: 1.26e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 240 MIQAVLNIVRNAMqaiagqKHDMGLGRISLRTRtlrqftightRHRLVVKVEIIDNGPGIPPELQETIFYPMVSGRAD-- 317
Cdd:cd00075 1 LEQVLSNLLDNAL------KYSPPGGTIEISLR----------QEGDGVVLEVEDNGPGIPEEDLERIFERFYRGDKSre 64
|
90 100 110
....*....|....*....|....*....|....*...
gi 2490585947 318 --GTGLGLAITQNIISQHQGLIECESHVGH-TVFSIFL 352
Cdd:cd00075 65 ggGTGLGLAIVRRIVEAHGGRITVESEPGGgTTFTVTL 102
|
|
| HATPase_c |
pfam02518 |
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the ... |
236-356 |
7.18e-19 |
|
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the structurally related ATPase domains of histidine kinase, DNA gyrase B and HSP90.
Pssm-ID: 460579 [Multi-domain] Cd Length: 109 Bit Score: 80.88 E-value: 7.18e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 236 DREQMIQAVLNIVRNAMqaiagqKHDMGLGRISLRTRTLRQFTIghtrhrlvvkvEIIDNGPGIPPELQETIFYPMVSGR 315
Cdd:pfam02518 2 DELRLRQVLSNLLDNAL------KHAAKAGEITVTLSEGGELTL-----------TVEDNGIGIPPEDLPRIFEPFSTAD 64
|
90 100 110 120
....*....|....*....|....*....|....*....|....*
gi 2490585947 316 AD---GTGLGLAITQNIISQHQGLIECESHVGH-TVFSIFLPLEQ 356
Cdd:pfam02518 65 KRgggGTGLGLSIVRKLVELLGGTITVESEPGGgTTVTLTLPLAQ 109
|
|
| envZ |
PRK09467 |
osmolarity sensor protein; Provisional |
134-356 |
7.43e-18 |
|
osmolarity sensor protein; Provisional
Pssm-ID: 236531 [Multi-domain] Cd Length: 435 Bit Score: 84.19 E-value: 7.43e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 134 LLVRGLAHEIKNPLGGIRGAAQLLSRElpNEELKDYTNVIIEEADRLRNLVDRMLGSNKLPSLAMTNVHEVLERVAnLIE 213
Cdd:PRK09467 231 LLMAGVSHDLRTPLTRIRLATEMMSEE--DGYLAESINKDIEECNAIIEQFIDYLRTGQEMPMEMADLNALLGEVI-AAE 307
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 214 AECQGGITLvrDYDPSIPDLLIDREQMIQAVLNIVRNAMQaiagqkhdMGLGRISLRTrtlrqftiGHTRHRLVVKVEii 293
Cdd:PRK09467 308 SGYEREIET--ALQPGPIEVPMNPIAIKRALANLVVNAAR--------YGNGWIKVSS--------GTEGKRAWFQVE-- 367
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2490585947 294 DNGPGIPPELQETIFYPMVSG-RA---DGTGLGLAITQNIISQHQGLIECESHV-GHTVFSIFLPLEQ 356
Cdd:PRK09467 368 DDGPGIPPEQLKHLFQPFTRGdSArgsSGTGLGLAIVKRIVDQHNGKVELGNSEeGGLSARAWLPLTT 435
|
|
| HATPase_NtrY-like |
cd16944 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
236-340 |
1.09e-16 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Azorhizobium caulinodans NtrY; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs) such as Azorhizobium caulinodans ORS571 NtrY of the NtrY-NtrX TCS, which is involved in nitrogen fixation and metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also have PAS sensor domains.
Pssm-ID: 340420 [Multi-domain] Cd Length: 108 Bit Score: 74.88 E-value: 1.09e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 236 DREQMIQAVLNIVRNAMQAIAGQKHDMGLGRISLRTrtlrqftigHTRHRLVVkvEIIDNGPGIPPELQETIFYPMVSGR 315
Cdd:cd16944 1 DTTQISQVLTNILKNAAEAIEGRPSDVGEVRIRVEA---------DQDGRIVL--IVCDNGKGFPREMRHRATEPYVTTR 69
|
90 100
....*....|....*....|....*
gi 2490585947 316 ADGTGLGLAITQNIISQHQGLIECE 340
Cdd:cd16944 70 PKGTGLGLAIVKKIMEEHGGRISLS 94
|
|
| cpxA |
PRK09470 |
envelope stress sensor histidine kinase CpxA; |
135-356 |
2.36e-16 |
|
envelope stress sensor histidine kinase CpxA;
Pssm-ID: 236532 [Multi-domain] Cd Length: 461 Bit Score: 79.98 E-value: 2.36e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 135 LVRGLAHEIKNPLGGIRGAAQLLSRElpNEELKDYTNviIE-EADRLrnlvDRMLgsNKLPSLAMTNVHEVLER---VAN 210
Cdd:PRK09470 246 LLSDISHELRTPLTRLQLATALLRRR--QGESKELER--IEtEAQRL----DSMI--NDLLVLSRNQQKNHLERetfKAN 315
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 211 LI----------EAEcQGGITLVRDYDPSIPDLLIDREQMIQAVLNIVRNAMQAiaGQKHdmglgrISLrtrtlrQFTIg 280
Cdd:PRK09470 316 SLwsevledakfEAE-QMGKSLTVSAPPGPWPINGNPNALASALENIVRNALRY--SHTK------IEV------AFSV- 379
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 281 hTRHRLVVKVEiiDNGPGIPPELQETIFYPM--VSGRAD----GTGLGLAITQNIISQHQGLIECE-SHVGHTVFSIFLP 353
Cdd:PRK09470 380 -DKDGLTITVD--DDGPGVPEEEREQIFRPFyrVDEARDresgGTGLGLAIVENAIQQHRGWVKAEdSPLGGLRLTIWLP 456
|
...
gi 2490585947 354 LEQ 356
Cdd:PRK09470 457 LYK 459
|
|
| HATPase_EvgS-ArcB-TorS-like |
cd16922 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases, many are hybrid ... |
265-354 |
2.45e-16 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases, many are hybrid sensor histidine kinases, similar to Escherichia coli EvgS, ArcB, TorS, BarA, RcsC; This family contains the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinases (HKs), including the following Escherichia coli HKs: EvgS, a HK of the EvgS-EvgA two-component system (TCS) that confers acid resistance; ArcB, a HK of the ArcB-ArcA TCS that modulates the expression of numerous genes in response to respiratory growth conditions; TorS, a HK of the TorS-TorR TCS which is involved in the anaerobic utilization of trimethylamine-N-oxide; BarA, a HK of the BarA-UvrY TCS involved in the regulation of carbon metabolism; and RcsC, a HK of the RcsB-RcsC TCS which regulates the expression of the capsule operon and of the cell division gene ftsZ. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), with most having accessory sensor domain(s) such as GAF, PAS and CHASE; many are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340399 [Multi-domain] Cd Length: 110 Bit Score: 74.07 E-value: 2.45e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 265 GRISLRTRTlrqftIGHTRHRLVVKVEIIDNGPGIPPELQETIFYPMV------SGRADGTGLGLAITQNIISQHQGLIE 338
Cdd:cd16922 19 GEVTLRVSL-----EEEEEDGVQLRFSVEDTGIGIPEEQQARLFEPFSqadsstTRKYGGTGLGLAISKKLVELMGGDIS 93
|
90
....*....|....*..
gi 2490585947 339 CESHVGH-TVFSIFLPL 354
Cdd:cd16922 94 VESEPGQgSTFTFTLPL 110
|
|
| PRK09303 |
PRK09303 |
histidine kinase; |
105-345 |
7.56e-16 |
|
histidine kinase;
Pssm-ID: 236462 [Multi-domain] Cd Length: 380 Bit Score: 78.07 E-value: 7.56e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 105 LLLLEvhprDRLLRITKEEAQLSKQETTK-LLVRGLAHEIKNPLGGIRGAAQLL-------SRELPNEELKDYTNVI--- 173
Cdd:PRK09303 127 LLQLS----DELFVLRQENETLLEQLKFKdRVLAMLAHDLRTPLTAASLALETLelgqideDTELKPALIEQLQDQArrq 202
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 174 IEEADRL-RNLVDRMLGSNK----------LPSLAMtnvhEVLERVANLIEAEcqgGITLVRDYDPSIPDLLIDREQMIQ 242
Cdd:PRK09303 203 LEEIERLiTDLLEVGRTRWEalrfnpqkldLGSLCQ----EVILELEKRWLAK---SLEIQTDIPSDLPSVYADQERIRQ 275
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 243 AVLNIVRNAMqaiagqKH--DMGLGRISLRTRTLRQftightrhrlvVKVEIIDNGPGIPPELQETIFYPMV----SGRA 316
Cdd:PRK09303 276 VLLNLLDNAI------KYtpEGGTITLSMLHRTTQK-----------VQVSICDTGPGIPEEEQERIFEDRVrlprDEGT 338
|
250 260
....*....|....*....|....*....
gi 2490585947 317 DGTGLGLAITQNIISQHQGLIECESHVGH 345
Cdd:PRK09303 339 EGYGIGLSVCRRIVRVHYGQIWVDSEPGQ 367
|
|
| HATPase_TmoS-FixL-DctS-like |
cd16920 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
242-353 |
2.25e-15 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Rhizobium meliloti FixL, and Rhodobacter capsulatus DctS; includes hybrid sensor histidine kinase similar to Pseudomonas mendocina TmoS; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs), such as Pseudomonas mendocina TmoS HK of the TmoS-TmoT TCS, which controls the expression of the toluene-4-monooxygenase pathway, Rhizobium meliloti FixL HK of the FixL-FixJ TCS, which regulates the expression of the genes related to nitrogen fixation in the root nodule in response to O(2) levels, and Rhodobacter capsulatus DctS of the DctS-DctR TCS, which controls synthesis of the high-affinity C4-dicarboxylate transport system. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and PAS sensor domain(s); many are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340397 [Multi-domain] Cd Length: 104 Bit Score: 71.27 E-value: 2.25e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 242 QAVLNIVRNAMQAIAGQkhdmglgrislrTRTLRQFTIGHTRHRL-VVKVEIIDNGPGIPPELQETIFYPMVSGRADGTG 320
Cdd:cd16920 3 QVLINLVRNGIEAMSEG------------GCERRELTIRTSPADDrAVTISVKDTGPGIAEEVAGQLFDPFYTTKSEGLG 70
|
90 100 110
....*....|....*....|....*....|....
gi 2490585947 321 LGLAITQNIISQHQGLIECESH-VGHTVFSIFLP 353
Cdd:cd16920 71 MGLSICRSIIEAHGGRLSVESPaGGGATFQFTLP 104
|
|
| PRK11466 |
PRK11466 |
hybrid sensory histidine kinase TorS; Provisional |
118-361 |
6.14e-15 |
|
hybrid sensory histidine kinase TorS; Provisional
Pssm-ID: 236914 [Multi-domain] Cd Length: 914 Bit Score: 76.10 E-value: 6.14e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 118 RITKEEAQLSKQETTKLLVrGLAHEIKNPLGGIRGAAQLLSRELPNEELKDYTNVIIEEADRLRNLVDRML--------G 189
Cdd:PRK11466 431 RQARAEAEKASQAKSAFLA-AMSHEIRTPLYGILGTAQLLADNPALNAQRDDLRAITDSGESLLTILNDILdysaieagG 509
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 190 SNKLPSLAMTNVHEVLERVANLIEAECQGG-ITLVRDYDPSIPDLLI-DREQMIQAVLNIVRNAMQAIAGqkhdmglGRI 267
Cdd:PRK11466 510 KNVSVSDEPFEPRPLLESTLQLMSGRVKGRpIRLATDIADDLPTALMgDPRRIRQVITNLLSNALRFTDE-------GSI 582
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 268 SLRTRTLRQftightrHRLvvkVEIIDNGPGIPPELQETIFYPMV--SGRADGTGLGLAITQNIISQHQGLIECES--HV 343
Cdd:PRK11466 583 VLRSRTDGE-------QWL---VEVEDSGCGIDPAKLAEIFQPFVqvSGKRGGTGLGLTISSRLAQAMGGELSATStpEV 652
|
250
....*....|....*...
gi 2490585947 344 GhTVFSIFLPLEQGAPTP 361
Cdd:PRK11466 653 G-SCFCLRLPLRVATAPV 669
|
|
| HisKA |
pfam00512 |
His Kinase A (phospho-acceptor) domain; dimerization and phospho-acceptor domain of histidine ... |
135-188 |
2.56e-14 |
|
His Kinase A (phospho-acceptor) domain; dimerization and phospho-acceptor domain of histidine kinases.
Pssm-ID: 459839 [Multi-domain] Cd Length: 66 Bit Score: 66.85 E-value: 2.56e-14
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....
gi 2490585947 135 LVRGLAHEIKNPLGGIRGAAQLLSRELPNEELKDYTNVIIEEADRLRNLVDRML 188
Cdd:pfam00512 5 FLANLSHELRTPLTAIRGYLELLRDEKLDEEQREYLETILRSAERLLRLINDLL 58
|
|
| PRK11107 |
PRK11107 |
hybrid sensory histidine kinase BarA; Provisional |
141-355 |
3.07e-14 |
|
hybrid sensory histidine kinase BarA; Provisional
Pssm-ID: 236848 [Multi-domain] Cd Length: 919 Bit Score: 74.12 E-value: 3.07e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 141 HEIKNPLGGIRG-AAQLLSRELpNEELKDYTNVIIEEADRLRNLVDRMLGSNKLPSLAMT------NVHEVLERVANLIE 213
Cdd:PRK11107 302 HELRTPLNGVIGfTRQTLKTPL-TPTQRDYLQTIERSANNLLAIINDILDFSKLEAGKLVlenipfSLRETLDEVVTLLA 380
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 214 AECQG-GITLVRDYDPSIPDLLI-DREQMIQAVLNIVRNAMQAIagqkhDMGLGRISLRTRTLRQftightrHRLVVKVE 291
Cdd:PRK11107 381 HSAHEkGLELTLNIDPDVPDNVIgDPLRLQQIITNLVGNAIKFT-----ESGNIDILVELRALSN-------TKVQLEVQ 448
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2490585947 292 IIDNGPGIPPELQETIFYPMvsGRAD--------GTGLGLAITQNIISQHQGLIECESHVGH-TVFSIFLPLE 355
Cdd:PRK11107 449 IRDTGIGISERQQSQLFQAF--RQADasisrrhgGTGLGLVITQKLVNEMGGDISFHSQPNRgSTFWFHLPLD 519
|
|
| PRK13557 |
PRK13557 |
histidine kinase; Provisional |
122-361 |
9.33e-14 |
|
histidine kinase; Provisional
Pssm-ID: 237425 [Multi-domain] Cd Length: 540 Bit Score: 72.40 E-value: 9.33e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 122 EEA--QLSKQETTKLLVRGLAHEIKNPLGGIRGAAQLLsrELPNEELKDYTNVIIEEADRLRNLVDR--MLgSNKLPSLA 197
Cdd:PRK13557 151 EDAlrQAQKMEALGQLTGGIAHDFNNLLQVMSGYLDVI--QAALSHPDADRGRMARSVENIRAAAERaaTL-TQQLLAFA 227
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 198 --------MTNVHEVLERVANLIEAECQGGITLVRDYDPSIPDLLIDREQMIQAVLNIVRNAMQAIAGQkhdmglGRISL 269
Cdd:PRK13557 228 rkqrlegrVLNLNGLVSGMGELAERTLGDAVTIETDLAPDLWNCRIDPTQAEVALLNVLINARDAMPEG------GRVTI 301
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 270 RTRTLR-----QFTIGHTRHRLVVKVEIIDNGPGIPPELQETIFYPMVS--GRADGTGLGLAITQNIISQHQGLIECESH 342
Cdd:PRK13557 302 RTRNVEiededLAMYHGLPPGRYVSIAVTDTGSGMPPEILARVMDPFFTtkEEGKGTGLGLSMVYGFAKQSGGAVRIYSE 381
|
250 260
....*....|....*....|
gi 2490585947 343 VGH-TVFSIFLPLEQGAPTP 361
Cdd:PRK13557 382 VGEgTTVRLYFPASDQAENP 401
|
|
| HATPase_CpxA-like |
cd16949 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
242-354 |
9.41e-14 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli CpxA; This family includes the histidine kinase-like ATPase (HATPase) domains of two-component sensor histidine kinase (HKs) similar to Escherichia coli CpxA, HK of the CpxA-CpxR two-component regulatory system (TCS) which may function in acid stress and in cell wall stability. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also contain a CpxA family periplasmic domain.
Pssm-ID: 340425 [Multi-domain] Cd Length: 104 Bit Score: 66.58 E-value: 9.41e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 242 QAVLNIVRNAMQAIAGQKHdmglgrISLrTRTLRQFTIghtrhrlvvkvEIIDNGPGIPPELQETIFYPMVsgRAD---- 317
Cdd:cd16949 3 RALENVLRNALRYSPSKIL------LDI-SQDGDQWTI-----------TITDDGPGVPEDQLEQIFLPFY--RVDsard 62
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 2490585947 318 ----GTGLGLAITQNIISQHQGLIECE-SHVGHTVFSIFLPL 354
Cdd:cd16949 63 resgGTGLGLAIAERAIEQHGGKIKASnRKPGGLRVRIWLPA 104
|
|
| PRK15347 |
PRK15347 |
two component system sensor kinase; |
110-359 |
2.47e-12 |
|
two component system sensor kinase;
Pssm-ID: 237951 [Multi-domain] Cd Length: 921 Bit Score: 68.13 E-value: 2.47e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 110 VHPRDRLLRITKEEA-QLSKQETTKLLVrgLAHEIKNPLGGIRGAAQLLSR-ELPNEELK---------DYTNVIIEead 178
Cdd:PRK15347 377 VAERTQALAEAKQRAeQANKRKSEHLTT--ISHEIRTPLNGVLGALELLQNtPLTAEQMDladtarqctLSLLAIIN--- 451
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 179 rlrNLVD--RMLGSNKLPSLAMTNVHEVLERVANLIEAECQG-GITLVRDYDPSIP-DLLIDREQMIQAVLNIVRNAMQA 254
Cdd:PRK15347 452 ---NLLDfsRIESGQMTLSLEETALLPLLDQAMLTIQGPAQSkSLTLRTFVGAHVPlYLHLDSLRLRQILVNLLGNAVKF 528
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 255 IAGqkhdmglGRISLRTRtlrqftigHTRHRLVVKVEiiDNGPGIPPELQETIFYPM--VSGRADGTGLGLAITQNIISQ 332
Cdd:PRK15347 529 TET-------GGIRLRVK--------RHEQQLCFTVE--DTGCGIDIQQQQQIFTPFyqADTHSQGTGLGLTIASSLAKM 591
|
250 260
....*....|....*....|....*...
gi 2490585947 333 HQGLIECESHVGH-TVFSIFLPLEQGAP 359
Cdd:PRK15347 592 MGGELTLFSTPGVgSCFSLVLPLNEYAP 619
|
|
| HisKA |
smart00388 |
His Kinase A (phosphoacceptor) domain; Dimerisation and phosphoacceptor domain of histidine ... |
135-188 |
3.06e-12 |
|
His Kinase A (phosphoacceptor) domain; Dimerisation and phosphoacceptor domain of histidine kinases.
Pssm-ID: 214644 [Multi-domain] Cd Length: 66 Bit Score: 61.04 E-value: 3.06e-12
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....
gi 2490585947 135 LVRGLAHEIKNPLGGIRGAAQLLSRELPNEELKDYTNVIIEEADRLRNLVDRML 188
Cdd:smart00388 5 FLANLSHELRTPLTAIRGYLELLLDTELSEEQREYLETILREAERLLRLINDLL 58
|
|
| HATPase_DpiB-CitA-like |
cd16915 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
246-353 |
3.65e-12 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli K-12 DpiB, DcuS, and Bacillus subtilis CitS, DctS, and YufL; This family includes histidine kinase-like ATPase domains of Escherichia coli K-12 DpiB and DcuS, and Bacillus subtilis CitS, DctS and MalK histidine kinases (HKs) all of which are two component transduction systems (TCSs). E. coli K-12 DpiB (also known as CitA) is the histidine kinase (HK) of DpiA-DpiB, a two-component signal transduction system (TCS) required for the expression of citrate-specific fermentation genes and genes involved in plasmid inheritance. E. coli K-12 DcuS (also known as YjdH) is the HK of DcuS-DcuR, a TCS that in the presence of the extracellular C4-dicarboxlates, activates the expression of the genes of anaerobic fumarate respiration and of aerobic C4-dicarboxylate uptake. CitS is the HK of Bacillus subtilis CitS-CitT, a TCS which regulates expression of CitM, the Mg-citrate transporter. Bacillus subtilis DctS forms a tripartite sensor unit (DctS/DctA/DctB) for sensing C4 dicarboxylates. Bacillus subtilis MalK (also known as YfuL) is the HK of MalK-MalR (YufL-YufM) a TCS which regulates the expression of the malate transporters MaeN (YufR) and YflS, and is essential for utilization of malate in minimal medium. Proteins having this DpiB-CitA-like HATPase domain generally have sensor domains such as Cache and PAS, and a histidine kinase A (HisKA)-like SpoOB-type, alpha-helical domain.
Pssm-ID: 340392 [Multi-domain] Cd Length: 104 Bit Score: 62.30 E-value: 3.65e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 246 NIVRNAMQAIAGQkhDMGLGRISLRTRTLRQFtightrhrlvVKVEIIDNGPGIPPELQETIFYPMVSGRADGT-GLGLA 324
Cdd:cd16915 7 NLIDNALDALAAT--GAPNKQVEVFLRDEGDD----------LVIEVRDTGPGIAPELRDKVFERGVSTKGQGErGIGLA 74
|
90 100 110
....*....|....*....|....*....|
gi 2490585947 325 ITQNIISQHQGLIECESHV-GHTVFSIFLP 353
Cdd:cd16915 75 LVRQSVERLGGSITVESEPgGGTTFSIRIP 104
|
|
| HisKA |
cd00082 |
Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed ... |
135-188 |
5.43e-12 |
|
Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via trans-autophosphorylation by the catalytic domain of the histidine kinase. They subsequently transfer the phosphoryl group to the Asp acceptor residue of a response regulator protein. Two-component signalling systems, consisting of a histidine protein kinase that senses a signal input and a response regulator that mediates the output, are ancient and evolutionarily conserved signaling mechanisms in prokaryotes and eukaryotes.
Pssm-ID: 119399 [Multi-domain] Cd Length: 65 Bit Score: 60.30 E-value: 5.43e-12
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 2490585947 135 LVRGLAHEIKNPLGGIRGAAQLLSREL-PNEELKDYTNVIIEEADRLRNLVDRML 188
Cdd:cd00082 7 FLANVSHELRTPLTAIRGALELLEEELlDDEEQREYLERIREEAERLLRLINDLL 61
|
|
| HATPase_CckA-like |
cd16919 |
Histidine kinase-like ATPase domain of two-component sensor hybrid histidine kinases, similar ... |
242-353 |
7.36e-12 |
|
Histidine kinase-like ATPase domain of two-component sensor hybrid histidine kinases, similar to Brucella abortus 2308 CckA; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinase (HKs) similar to Brucella abortus 2308 CckA, which is a component of an essential protein phosphorelay that regulates expression of genes required for growth, division, and intracellular survival; phosphoryl transfer initiates from the sensor kinase CckA and proceeds via the ChpT phosphotransferase to two regulatory substrates: the DNA-binding response regulator CtrA and the phospho-receiver protein CpdR. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), a REC signal receiver domain, and some contain PAS or PAS and GAF sensor domain(s).
Pssm-ID: 340396 [Multi-domain] Cd Length: 116 Bit Score: 61.63 E-value: 7.36e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 242 QAVLNIVRNAMQAIAGQkhdmglGRISLRTRTLRQFTIGHTRHRLV-----VKVEIIDNGPGIPPELQETIFYPMVS--G 314
Cdd:cd16919 3 LAILNLAVNARDAMPEG------GRLTIETSNQRVDADYALNYRDLipgnyVCLEVSDTGSGMPAEVLRRAFEPFFTtkE 76
|
90 100 110 120
....*....|....*....|....*....|....*....|
gi 2490585947 315 RADGTGLGLAITQNIISQHQGLIECESHVGH-TVFSIFLP 353
Cdd:cd16919 77 VGKGTGLGLSMVYGFVKQSGGHLRIYSEPGVgTTVRIYLP 116
|
|
| HATPase_HupT_MifS-like |
cd16976 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
240-352 |
1.11e-11 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Rhodobacter capsulatus HupT and Pseudomonas aeruginosa MifS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Rhodobacter capsulatus HupT of the HupT-HupR two-component regulatory system (TCS), which regulates the synthesis of HupSL, a membrane bound [NiFe]hydrogenase. It also contains the HATPase domain of Pseudomonas aeruginosa MifS, the HK of the MifS-MifR TCS, which may be involved in sensing alpha-ketoglutarate and regulating its transport and subsequent metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some also have a C-terminal PAS sensor domain.
Pssm-ID: 340435 [Multi-domain] Cd Length: 102 Bit Score: 60.93 E-value: 1.11e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 240 MIQAVLNIVRNAMQAIAGQKHdmglGRISLRTRTLRQftightrhRLVVKVEiiDNGPGIPPELQETIFYPMVSGR--AD 317
Cdd:cd16976 1 IQQVLMNLLQNALDAMGKVEN----PRIRIAARRLGG--------RLVLVVR--DNGPGIAEEHLSRVFDPFFTTKpvGK 66
|
90 100 110
....*....|....*....|....*....|....*.
gi 2490585947 318 GTGLGLAITQNIISQHQGLIECESH-VGHTVFSIFL 352
Cdd:cd16976 67 GTGLGLSISYGIVEEHGGRLSVANEeGAGARFTFDL 102
|
|
| phoR |
PRK11006 |
phosphate regulon sensor histidine kinase PhoR; |
141-353 |
1.89e-11 |
|
phosphate regulon sensor histidine kinase PhoR;
Pssm-ID: 182895 [Multi-domain] Cd Length: 430 Bit Score: 65.03 E-value: 1.89e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 141 HEIKNPLGGIRGAAQLLS-RELPNEELKDYTNVIIEEADRLRNLVDRMLGSNKLPSLAMTNVHE---------VLERVAN 210
Cdd:PRK11006 213 HELRTPLTVLQGYLEMMQdQPLEGALREKALHTMREQTQRMEGLVKQLLTLSKIEAAPTIDLNEkvdvpmmlrVLEREAQ 292
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 211 LIEAECQggiTLVRDYDPSIpDLLIDREQMIQAVLNIVRNAMqaiagqKHDMGLGRISLRTRtlrqftigHTRHRLVVKV 290
Cdd:PRK11006 293 TLSQGKH---TITFEVDNSL-KVFGNEDQLRSAISNLVYNAV------NHTPEGTHITVRWQ--------RVPQGAEFSV 354
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2490585947 291 EiiDNGPGIPPE----LQETiFYPMVSGRA---DGTGLGLAITQNIISQHQGLIECESHVGH-TVFSIFLP 353
Cdd:PRK11006 355 E--DNGPGIAPEhiprLTER-FYRVDKARSrqtGGSGLGLAIVKHALSHHDSRLEIESEVGKgTRFSFVLP 422
|
|
| PRK11091 |
PRK11091 |
aerobic respiration control sensor protein ArcB; Provisional |
139-354 |
2.63e-11 |
|
aerobic respiration control sensor protein ArcB; Provisional
Pssm-ID: 236842 [Multi-domain] Cd Length: 779 Bit Score: 64.96 E-value: 2.63e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 139 LAHEIKNPLGGIRGaaqlLSRELPNEELKD----YTNVIIEEADRLRNL------VDRMlGSNKLP-SLAMTNVHEVLER 207
Cdd:PRK11091 290 ISHELRTPLNGIVG----LSRILLDTELTAeqrkYLKTIHVSAITLGNIfndiidMDKM-ERRKLQlDNQPIDFTDFLAD 364
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 208 VANL--IEAEcQGGITLVRDYDPSIPDLLI-DREQMIQAVLNIVRNAMQAIagQKhdmglGRISLRTRTlrqftigHTRH 284
Cdd:PRK11091 365 LENLsgLQAE-QKGLRFDLEPLLPLPHKVItDGTRLRQILWNLISNAVKFT--QQ-----GGVTVRVRY-------EEGD 429
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2490585947 285 RLVVKVEiiDNGPGIPPELQETIF--YPMVSGRAD-----GTGLGLAITQNIISQHQGLIECESHVGH-TVFSIFLPL 354
Cdd:PRK11091 430 MLTFEVE--DSGIGIPEDELDKIFamYYQVKDSHGgkpatGTGIGLAVSKRLAQAMGGDITVTSEEGKgSCFTLTIHA 505
|
|
| HATPase_EnvZ-like |
cd16950 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
240-338 |
5.87e-11 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli EnvZ and Pseudomonas aeruginosa BfmS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Escherichia coli EnvZ of the EnvZ-OmpR two-component regulatory system (TCS), which functions in osmoregulation. It also contains the HATPase domain of Pseudomonas aeruginosa BfmS, the HK of the BfmSR TCS, which functions in the regulation of the rhl quorum-sensing system and bacterial virulence in P. aeruginosa. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also contain a periplasmic domain.
Pssm-ID: 340426 [Multi-domain] Cd Length: 101 Bit Score: 58.61 E-value: 5.87e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 240 MIQAVLNIVRNAMQaiagqkhdMGLGRISLRTRTlrqftighTRHRLVVKVEiiDNGPGIPPELQETIFYPMVSGRA--- 316
Cdd:cd16950 1 LKRVLSNLVDNALR--------YGGGWVEVSSDG--------EGNRTRIQVL--DNGPGIAPEEVDELFQPFYRGDNarg 62
|
90 100
....*....|....*....|...
gi 2490585947 317 -DGTGLGLAITQNIISQHQGLIE 338
Cdd:cd16950 63 tSGTGLGLAIVQRISDAHGGSLT 85
|
|
| PRK11086 |
PRK11086 |
sensory histidine kinase DcuS; Provisional |
219-357 |
6.71e-11 |
|
sensory histidine kinase DcuS; Provisional
Pssm-ID: 236839 [Multi-domain] Cd Length: 542 Bit Score: 63.39 E-value: 6.71e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 219 GITLVRDYDPSIPDllIDREQMIqAVL-----NIVRNAMQAIAGQKHdmglGRISLrtrtlrQFTIGHTRhrlvVKVEII 293
Cdd:PRK11086 411 GITLIISEDSQLPD--SGDEDQV-HELitilgNLIENALEAVGGEEG----GEISV------SLHYRNGW----LHCEVS 473
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2490585947 294 DNGPGIPPELQETIFYPMVSGRADGTGLGLAITQNIISQHQGLIECESHVG-HTVFSIFLPLEQG 357
Cdd:PRK11086 474 DDGPGIAPDEIDAIFDKGYSTKGSNRGVGLYLVKQSVENLGGSIAVESEPGvGTQFFVQIPWDGE 538
|
|
| HATPase_RstB-like |
cd16939 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
240-354 |
1.33e-10 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Salmonella typhimurium RstB; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Salmonella typhimurium RstB HK of the RstA-RstB two-component regulatory system (TCS), which regulates expression of the constituents participating in pyrimidine metabolism and iron acquisition, and may be required for regulation of Salmonella motility and invasion. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and a HAMP sensor domain.
Pssm-ID: 340416 [Multi-domain] Cd Length: 104 Bit Score: 57.83 E-value: 1.33e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 240 MIQAVLNIVRNAMQAIAGQKhdmglgRISLRTRTlrqftightrHRLVVKVEiiDNGPGIPPELQETIFYPMVsgRAD-- 317
Cdd:cd16939 1 MARALDNLLRNALRYAHRTV------RIALLVSG----------GRLTLIVE--DDGPGIPAAARERVFEPFV--RLDps 60
|
90 100 110 120
....*....|....*....|....*....|....*....|....
gi 2490585947 318 ------GTGLGLAITQNIISQHQGLIEC-ESHVGHTVFSIFLPL 354
Cdd:cd16939 61 rdratgGFGLGLAIVHRVALWHGGHVECdDSELGGACFRLTWPR 104
|
|
| HATPase_FilI-like |
cd16921 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
294-353 |
2.09e-10 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Methanosaeta harundinacea FilI and some hybrid sensor histidine kinases; This family includes FilI, the histidine kinase (HK) component of FilI-FilRs, a two-component signal transduction system (TCS) of the methanogenic archaeon, Methanosaeta harundinacea, which is involved in regulating methanogenesis. The cytoplasmic HK core consists of a C-terminal HK-like ATPase domain (represented here) and a histidine kinase dimerization and phosphoacceptor domain (HisKA) domain, which, in FilI, are coupled to CHASE, HAMP, PAS, and GAF sensor domains. FilI-FilRs catalyzes the phosphotransfer between FilI (HK) and FilRs (FilR1 and FilR2, response regulators) of the TCS. TCSs are predicted to be of bacterial origin, and acquired by archaea by horizontal gene transfer. This model also includes related HATPase domains such as that of Synechocystis sp. PCC6803 phytochrome-like protein Cph1. Proteins having this HATPase domain and HisKA domain also have accessory sensor domains such as CHASE, GAF, HAMP and PAS; some are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340398 [Multi-domain] Cd Length: 105 Bit Score: 57.34 E-value: 2.09e-10
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2490585947 294 DNGPGIPPELQETIF--YPMVSGRAD--GTGLGLAITQNIISQHQGLIECESHVGH-TVFSIFLP 353
Cdd:cd16921 41 DNGIGIDPEYAEKVFgiFQRLHSREEyeGTGVGLAIVRKIIERHGGRIWLESEPGEgTTFYFTLP 105
|
|
| PRK09959 |
PRK09959 |
acid-sensing system histidine kinase EvgS; |
139-355 |
1.73e-09 |
|
acid-sensing system histidine kinase EvgS;
Pssm-ID: 182169 [Multi-domain] Cd Length: 1197 Bit Score: 59.36 E-value: 1.73e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 139 LAHEIKNPLGGIRGAAQLLSRE-LPNEELKDYTNVIIEEADRLRNLVDRMLGSNKLPSlAMTNVHEVLERVANLIEAECQ 217
Cdd:PRK09959 719 MSHEIRTPISSIMGFLELLSGSgLSKEQRVEAISLAYATGQSLLGLIGEILDVDKIES-GNYQLQPQWVDIPTLVQNTCH 797
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 218 --GGI----TLVRDYDPSIPD---LLIDREQMIQAVLNIVRNAMQAIAGqkhdmglGRISLRTrTLRQFTIGHTrhrlVV 288
Cdd:PRK09959 798 sfGAIaaskSIALSCSSTFPDhylVKIDPQAFKQVLSNLLSNALKFTTE-------GAVKITT-SLGHIDDNHA----VI 865
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2490585947 289 KVEIIDNGPGIPPELQETIF--YPMVS-GRAD-GTGLGLAITQNIISQHQGLIECESHVG-HTVFSIFLPLE 355
Cdd:PRK09959 866 KMTIMDSGSGLSQEEQQQLFkrYSQTSaGRQQtGSGLGLMICKELIKNMQGDLSLESHPGiGTTFTITIPVE 937
|
|
| PRK10604 |
PRK10604 |
sensor protein RstB; Provisional |
133-361 |
3.81e-09 |
|
sensor protein RstB; Provisional
Pssm-ID: 236724 [Multi-domain] Cd Length: 433 Bit Score: 57.69 E-value: 3.81e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 133 KLLVRGLAHEIKNPLGGIR-----------GAAQLLSRELpneelkDYTNVIIEEA---DRL-RNLVDRMLGSNKLPSLA 197
Cdd:PRK10604 213 KQLIDGIAHELRTPLVRLRyrlemsdnlsaAESQALNRDI------GQLEALIEELltyARLdRPQNELHLSEPDLPAWL 286
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 198 MTNVHEVlervaNLIEAECQGGITLVRDYDPSIPDL-LIDReqmiqAVLNIVRNAMQAIAGQkhdmglgrisLRTRTLRQ 276
Cdd:PRK10604 287 STHLADI-----QAVTPEKTVRLDTPHQGDYGALDMrLMER-----VLDNLLNNALRYAHSR----------VRVSLLLD 346
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 277 ftightRHRLVVKVEiiDNGPGIPPELQETIFYPMVsgRAD--------GTGLGLAITQNIISQHQGLIECE-SHVGHTV 347
Cdd:PRK10604 347 ------GNQACLIVE--DDGPGIPPEERERVFEPFV--RLDpsrdratgGCGLGLAIVHSIALAMGGSVNCDeSELGGAR 416
|
250
....*....|....
gi 2490585947 348 FSIFLPLEQGAPTP 361
Cdd:PRK10604 417 FSFSWPVWHNLPQF 430
|
|
| HATPase_BvrS-ChvG-like |
cd16953 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
240-342 |
6.41e-09 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Brucella abortus BvrS and Sinorhizobium meliloti ChvG; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Brucella abortus BvrS of the BvrR-BvrS two-component regulatory system (TCS), which controls cell invasion and intracellular survival, as well as Sinorhizobium meliloti and Agrobacterium tumefaciens ChvG of the ChvI-ChvG TCS necessary for endosymbiosis and pathogenicity in plants. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), an accessory HAMP sensor domain, a periplasmic stimulus-sensing domain, and some also have a sensor N-terminal transmembrane domain.
Pssm-ID: 340429 [Multi-domain] Cd Length: 110 Bit Score: 53.35 E-value: 6.41e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 240 MIQAVLNIVRNAMQAIAGQKhdmglGRISLRtrtlrqftIGHTRHRLVVKVEiiDNGPGIPPELQETIFYPMVSGRADG- 318
Cdd:cd16953 1 LGQVLRNLIGNAISFSPPDT-----GRITVS--------AMPTGKMVTISVE--DEGPGIPQEKLESIFDRFYTERPANe 65
|
90 100
....*....|....*....|....*....
gi 2490585947 319 -----TGLGLAITQNIISQHQGLIECESH 342
Cdd:cd16953 66 afgqhSGLGLSISRQIIEAHGGISVAENH 94
|
|
| PRK10490 |
PRK10490 |
sensor protein KdpD; Provisional |
288-355 |
6.81e-09 |
|
sensor protein KdpD; Provisional
Pssm-ID: 236701 [Multi-domain] Cd Length: 895 Bit Score: 57.35 E-value: 6.81e-09
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2490585947 288 VKVEIIDNGPGIPPELQETIFYPMVSGRAD----GTGLGLAITQNIISQHQGLIECESHV-GHTVFSIFLPLE 355
Cdd:PRK10490 811 LQLDVWDNGPGIPPGQEQLIFDKFARGNKEsaipGVGLGLAICRAIVEVHGGTIWAENRPeGGACFRVTLPLE 883
|
|
| HATPase_TutC-TodS-like |
cd16925 |
Histidine kinase-like ATPase domain of hybrid sensor histidine kinases similar to Pseudomonas ... |
236-353 |
7.61e-09 |
|
Histidine kinase-like ATPase domain of hybrid sensor histidine kinases similar to Pseudomonas putida TodS and Thauera aromatica TutC; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinase (HKs) such Pseudomonas putida TodS HK of the TodS-TodT two-component regulatory system (TCS) which controls the expression of a toluene degradation pathway. Thauera aromatica TutC may be part of a TCS that is involved in anaerobic toluene metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), PAS sensor domain(s) and a REC domain.
Pssm-ID: 340402 [Multi-domain] Cd Length: 110 Bit Score: 52.88 E-value: 7.61e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 236 DREQMIQAVLNIVRNAMQAIAGQkhdmglGRISLRtrtlrqFTIGHTRHRLVVkveIIDNGPGIPPELQETIFYPMVSGR 315
Cdd:cd16925 1 DAEKYERVVLNLLSNAFKFTPDG------GRIRCI------LEKFRLNRFLLT---VSDSGPGIPPNLREEIFERFRQGD 65
|
90 100 110 120
....*....|....*....|....*....|....*....|....*
gi 2490585947 316 AD------GTGLGLAITQNIISQHQGLIEC-ESHVGHTVFSIFLP 353
Cdd:cd16925 66 GSstrahgGTGLGLSIVKEFVELHGGTVTVsDAPGGGALFQVELP 110
|
|
| nifL_nitrog |
TIGR02938 |
nitrogen fixation negative regulator NifL; NifL is a modulator of the nitrogen fixation ... |
118-338 |
9.37e-09 |
|
nitrogen fixation negative regulator NifL; NifL is a modulator of the nitrogen fixation positive regulator protein NifA, and is therefore a negative regulator. It binds NifA. NifA and NifL are encoded by adjacent genes. [Central intermediary metabolism, Nitrogen fixation, Regulatory functions, Protein interactions]
Pssm-ID: 131984 [Multi-domain] Cd Length: 494 Bit Score: 56.84 E-value: 9.37e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 118 RITKEEAQLSKQETTKLLVRGLA---HEIKNPLGGIRGAAQLLSR---ELPNEELKDYTNVII----EEADRLRNLVDRM 187
Cdd:TIGR02938 259 RLSALQALMAEEERLEAIRETLSaaiHRLQGPMNLISAAISVLQRrgdDAGNPASAAMLQQALsagrEHMEALRQVIPQS 338
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 188 LGSNKLPslamTNVHEVLERVANLI-EAECQGGItlVRDYDPS--IPDLLIDREQMIQAVLNIVRNAMQAIAGQKhdmgl 264
Cdd:TIGR02938 339 PQEIVVP----VNLNQILRDVITLStPRLLAAGI--VVDWQPAatLPAILGRELQLRSLFKALVDNAIEAMNIKG----- 407
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2490585947 265 grisLRTRTLRQFTigHTRHRLVVkVEIIDNGPGIPPELQETIFYPMVSGRAD---GTGLGLAITQNIISQHQGLIE 338
Cdd:TIGR02938 408 ----WKRRELSITT--ALNGDLIV-VSILDSGPGIPQDLRYKVFEPFFTTKGGsrkHIGMGLSVAQEIVADHGGIID 477
|
|
| HATPase_PhoQ-like |
cd16954 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
219-352 |
3.67e-08 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli PhoQ and Providencia stuartii AarG; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Escherichia coli PhoQ and Providencia stuartii AarG. PhoQ is the histidine kinase (HK) of the PhoP-PhoQ two-component regulatory system (TCS), which responds to the levels of Mg2+ and Ca2+, controls virulence, mediates the adaptation to Mg2+-limiting environments, and regulates numerous cellular activities. Providencia stuartii AarG is a putative sensor kinase which controls the expression of the 2'-N-acetyltransferase and an intrinsic multiple antibiotic resistance (Mar) response in Providencia stuartii. The AarG product is similar to PhoQ in that it is able to restore wild-type levels of resistance to a Salmonella typhimurium phoQ mutant. However, the expression of the 2'-N-acetyltransferase gene and of aarP (a gene encoding a transcriptional activator of 2'-N-acetyltransferase) are not significantly affected by the levels of Mg2+ or Ca2+. Most proteins in this group contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some have an accessory HAMP sensor domain, and some have an intracellular membrane -interaction PhoQ sensor domain.
Pssm-ID: 340430 [Multi-domain] Cd Length: 135 Bit Score: 51.48 E-value: 3.67e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 219 GITLVRDYDPSIpDLLIDREQMIQAVLNIVRNAMqaiagqKHdmGLGRISLrtrTLRQftighTRHRLVVKVEiiDNGPG 298
Cdd:cd16954 18 GVSISLDISPEL-RFPGERNDLMELLGNLLDNAC------KW--CLEFVEV---TARQ-----TDGGLHLIVD--DDGPG 78
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 299 IPPELQETIFypmVSG-RAD----GTGLGLAITQNIISQHQG-LIECESHVGHTVFSIFL 352
Cdd:cd16954 79 VPESQRSKIF---QRGqRLDeqrpGQGLGLAIAKEIVEQYGGeLSLSDSPLGGARFEVVF 135
|
|
| HATPase_VanS-like |
cd16923 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
287-353 |
4.42e-08 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Enterococcus faecium VanS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Enterococcus faecium VanS HK of the VanS-VanR two-component regulatory system (TCS) which activates the transcription of vanH, vanA and vanX vancomycin resistance genes. It also contains Ecoli YedV and PcoS, probable members of YedW-YedV TCS and PcoS-PcoR TCS, repectively. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); most also have a HAMP sensor domain.
Pssm-ID: 340400 [Multi-domain] Cd Length: 102 Bit Score: 50.46 E-value: 4.42e-08
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2490585947 287 VVKVEIIDNGPGIPPELQETIFYPMVSG----RADGTGLGLAITQNIISQHQGLIECESHVGHTVFSIFLP 353
Cdd:cd16923 32 VVNIMFKNPSSHPLDFKLEKLFERFYRGdnsrNTEGAGLGLSIAKAIIELHGGSASAEYDDNHDLFKVRLP 102
|
|
| HATPase_BasS-like |
cd16940 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
236-344 |
5.60e-08 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli BasS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) similar to Escherichia coli BasS HK of the BasS-BasR two-component regulatory system (TCS). Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some contain a HAMP sensory domain, while some an N-terminal two-component sensor kinase domain.
Pssm-ID: 340417 [Multi-domain] Cd Length: 113 Bit Score: 50.48 E-value: 5.60e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 236 DREQMIQAVLNIVRNAMqaiagqKHDMGLGRISLRTrtlrqftigHTRHRLVVKVEiiDNGPGIPPELQETI---FYPMV 312
Cdd:cd16940 10 DALLLFLLLRNLVDNAV------RYSPQGSRVEIKL---------SADDGAVIRVE--DNGPGIDEEELEALferFYRSD 72
|
90 100 110
....*....|....*....|....*....|..
gi 2490585947 313 SGRADGTGLGLAITQNIISQHQGLIECESHVG 344
Cdd:cd16940 73 GQNYGGSGLGLSIVKRIVELHGGQIFLGNAQG 104
|
|
| PRK09835 |
PRK09835 |
Cu(+)/Ag(+) sensor histidine kinase; |
139-353 |
2.02e-07 |
|
Cu(+)/Ag(+) sensor histidine kinase;
Pssm-ID: 182101 [Multi-domain] Cd Length: 482 Bit Score: 52.47 E-value: 2.02e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 139 LAHEIKNPLGGIRGAAQL-LSRELPNEELKD--YTNviIEEADRLRNLVDRML-----GSNKL-PSLAMTNVHEVLERVA 209
Cdd:PRK09835 269 IAHEIRTPITNLITQTEIaLSQSRSQKELEDvlYSN--LEELTRMAKMVSDMLflaqaDNNQLiPEKKMLDLADEVGKVF 346
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 210 NLIEAECQG-GITLVRDYDPsiPDLLIDREQMIQAVLNIVRNAMQAI-AGQkhdmglgRISLRTRTLRQFtightrhrlv 287
Cdd:PRK09835 347 DFFEAWAEErGVELRFVGDP--CQVAGDPLMLRRAISNLLSNALRYTpAGE-------AITVRCQEVDHQ---------- 407
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2490585947 288 vkVEIIDNGPGIP------PELQETiFY---PMVSGRADGTGLGLAITQNIISQHQGLIECESHVGHTVFSIFLP 353
Cdd:PRK09835 408 --VQLVVENPGTPiapehlPRLFDR-FYrvdPSRQRKGEGSGIGLAIVKSIVVAHKGTVAVTSDARGTRFVISLP 479
|
|
| HATPase_EcPhoR-like |
cd16952 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
294-353 |
2.52e-07 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli PhoR; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Escherichia coli or Vibrio cholera PhoR, the histidine kinase (HK) of PhoB-PhoR a two-component signal transduction system (TCS) involved in phosphate regulation. PhoR monitors extracellular inorganic phosphate (Pi) availability and PhoB, the response regulator, regulates transcription of genes of the phosphate regulon. PhoR is a bifunctional histidine autokinase/phospho-PhoB phosphatase; in phosphate deficiency, it autophosphorylates and Pi is transferred to PhoB, and when environmental Pi is abundant, it removes the phosphoryl group from phosphorylated PhoB. Other roles of PhoB-PhoR TCS have been described, including motility, biofilm formation, intestinal colonization, and virulence in V. cholera. E.coli PhoR and Bacillus subtilis PhoR (whose HATPase domain belongs to a different family) sense very different signals in each bacterium. In E. coli the PhoR signal comes from phosphate transport mediated by the PstSCAB2 phosphate transporter and the PhoU chaperone-like protein while in B. subtilis, the PhoR activation signal comes from wall teichoic acid (WTA) metabolism.
Pssm-ID: 340428 [Multi-domain] Cd Length: 108 Bit Score: 48.74 E-value: 2.52e-07
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2490585947 294 DNGPGIPPE----LQETiFYPMVSGRA---DGTGLGLAITQNIISQHQGLIECESHVGH-TVFSIFLP 353
Cdd:cd16952 39 DTGPGIPPEhiprLTER-FYRVDIERCrntGGTGLGLAIVKHVMSRHDARLLIASELGKgSRFTCLFP 105
|
|
| HATPase_BaeS-like |
cd16946 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
236-340 |
3.19e-07 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli BasS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) similar to Escherichia coli BaeS HK of the BaeS/BaeR two-component regulatory system (TCS), which responds to envelope stress. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and a HAMP sensory domain.
Pssm-ID: 340422 [Multi-domain] Cd Length: 109 Bit Score: 48.23 E-value: 3.19e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 236 DREQMIQAVLNIVRNAMQAIagqkhDMGlGRISLRTRTLRQftightrhrlVVKVEIIDNGPGIPPELQETI---FYPMV 312
Cdd:cd16946 1 DRDRLQQLFVNLLENSLRYT-----DTG-GKLRIRAAQTPQ----------EVRLDVEDSAPGVSDDQLARLferFYRVE 64
|
90 100 110
....*....|....*....|....*....|.
gi 2490585947 313 SGR---ADGTGLGLAITQNIISQHQGLIECE 340
Cdd:cd16946 65 SSRnraSGGSGLGLAICHNIALAHGGTISAE 95
|
|
| COG3920 |
COG3920 |
Two-component sensor histidine kinase, HisKA and HATPase domains [Signal transduction ... |
118-359 |
7.30e-07 |
|
Two-component sensor histidine kinase, HisKA and HATPase domains [Signal transduction mechanisms];
Pssm-ID: 443125 [Multi-domain] Cd Length: 495 Bit Score: 50.67 E-value: 7.30e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 118 RITKEEAQLSKQETTK-LLVRGLAHEIKNPLGGIRGAAQLLSRELPNEELKDytnvIIEEA-DRLR--NLVDRMLGSNKl 193
Cdd:COG3920 280 ERKRAEEELEASLEEKeLLLRELHHRVKNNLQVVSSLLRLQARRADDPEARE----ALEESqNRIQalALVHELLYQSE- 354
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 194 pSLAMTNVHEVLER-VANLIEAECQGGITLVRDydpsIPDLLIDREQMIQA--VLN-IVRNAMqaiagqKH---DMGLGR 266
Cdd:COG3920 355 -DWEGVDLRDYLRElLEPLRDSYGGRGIRIELD----GPDVELPADAAVPLglILNeLVTNAL------KHaflSGEGGR 423
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 267 ISLRtrtlrqFTIGHTRHRLVVKveiiDNGPGIPPELQEtifypmvsgrADGTGLGLAITQNIISQHQGLIECESHVGhT 346
Cdd:COG3920 424 IRVS------WRREDGRLRLTVS----DNGVGLPEDVDP----------PARKGLGLRLIRALVRQLGGTLELDRPEG-T 482
|
250
....*....|...
gi 2490585947 347 VFSIFLPLEQGAP 359
Cdd:COG3920 483 RVRITFPLAELAA 495
|
|
| COG4192 |
COG4192 |
Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal ... |
131-337 |
4.31e-06 |
|
Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal transduction mechanisms];
Pssm-ID: 443346 [Multi-domain] Cd Length: 640 Bit Score: 48.53 E-value: 4.31e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 131 TTKLLVRG-----LAHEIKNPLGGIRgaAQLLSRELPNEelKDYTNVIIEEADRLRNLVDRMLG--------SNKLP-SL 196
Cdd:COG4192 427 AAKMAVVGqtmtsLAHELNQPLNAMS--MYLFSAKKALE--QENYAQLPTSLDKIEGLIERMDKiikslrqfSRKSDtPL 502
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 197 AMTNVHEVLERVANLIEAEC---QGGITLvrdydPSIPDLLIDREQMIQAVLNIVRNAMQAIAGQKhdmglgrislrtrt 273
Cdd:COG4192 503 QPVDLRQVIEQAWELVESRAkpqQITLHI-----PDDLMVQGDQVLLEQVLVNLLVNALDAVATQP-------------- 563
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2490585947 274 lrQFTIGHTRHRLVVKVEIIDNGPGIPpeLQETIFYPMVSGRADGTGLGLAITQNIISQHQGLI 337
Cdd:COG4192 564 --QISVDLLSNAENLRVAISDNGNGWP--LVDKLFTPFTTTKEVGLGLGLSICRSIMQQFGGDL 623
|
|
| PRK10815 |
PRK10815 |
two-component system sensor histidine kinase PhoQ; |
281-337 |
6.05e-06 |
|
two-component system sensor histidine kinase PhoQ;
Pssm-ID: 182754 [Multi-domain] Cd Length: 485 Bit Score: 47.71 E-value: 6.05e-06
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2490585947 281 HTRHRLVVKVEiiDNGPGIPPELQETIFypmVSG-RAD----GTGLGLAITQNIISQHQGLI 337
Cdd:PRK10815 404 QTDEHLHIVVE--DDGPGIPESKRELIF---DRGqRADtlrpGQGLGLSVAREITEQYEGKI 460
|
|
| PRK10549 |
PRK10549 |
two-component system sensor histidine kinase BaeS; |
141-355 |
7.06e-06 |
|
two-component system sensor histidine kinase BaeS;
Pssm-ID: 182539 [Multi-domain] Cd Length: 466 Bit Score: 47.71 E-value: 7.06e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 141 HEIKNPLGGIRG---AAQLLSRELPNEELkdytNVIIEEADRLRNLVDRM--LGSNKLPSLA----MTNVHEVLE-RVAN 210
Cdd:PRK10549 249 HELRTPLAVLRGeleAIQDGVRKFTPESV----ASLQAEVGTLTKLVDDLhqLSLSDEGALAyrktPVDLVPLLEvAGGA 324
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 211 LIEAECQGGITLVRDYDPSIPdLLIDREQMIQAVLNIVRNamqaiagqkhdmglgriSLR-TRTLRQFTI-GHTRHRLVV 288
Cdd:PRK10549 325 FRERFASRGLTLQLSLPDSAT-VFGDPDRLMQLFNNLLEN-----------------SLRyTDSGGSLHIsAEQRDKTLR 386
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2490585947 289 kVEIIDNGPGIPPELQETI---FYPMVSGR---ADGTGLGLAITQNIISQHQGLIECE-SHVGHTVFSIFLPLE 355
Cdd:PRK10549 387 -LTFADSAPGVSDEQLQKLferFYRTEGSRnraSGGSGLGLAICLNIVEAHNGRIIAAhSPFGGVSITVELPLE 459
|
|
| YesM |
COG2972 |
Sensor histidine kinase YesM [Signal transduction mechanisms]; |
219-357 |
2.52e-05 |
|
Sensor histidine kinase YesM [Signal transduction mechanisms];
Pssm-ID: 442211 [Multi-domain] Cd Length: 445 Bit Score: 45.78 E-value: 2.52e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 219 GITLVRDYDPSIPDLLIDReQMIQavlNIVRNAMqaIAGQKHDMGLGRISLRTRtlrqftigHTRHRLVVkvEIIDNGPG 298
Cdd:COG2972 320 RLEVEIEIDEELLDLLIPK-LILQ---PLVENAI--EHGIEPKEGGGTIRISIR--------KEGDRLVI--TVEDNGVG 383
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2490585947 299 IPPELQETIFYPMvSGRADGTGLGLAITQNIISQHQGL-----IECESHVGHTVfSIFLPLEQG 357
Cdd:COG2972 384 MPEEKLEKLLEEL-SSKGEGRGIGLRNVRERLKLYYGEeygleIESEPGEGTTV-TIRIPLEEE 445
|
|
| PRK10337 |
PRK10337 |
sensor protein QseC; Provisional |
140-334 |
4.41e-05 |
|
sensor protein QseC; Provisional
Pssm-ID: 182388 [Multi-domain] Cd Length: 449 Bit Score: 45.03 E-value: 4.41e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 140 AHEIKNPLGGIRGAAQLLSRELPNEELKDYTNVIIEEA-DRLRNLVDRMLGSNKLPSLAmtNVHEVLERvanlieaecqg 218
Cdd:PRK10337 245 AHELRSPLAALKVQTEVAQLSDDDPQARKKALLQLHAGiDRATRLVDQLLTLSRLDSLD--NLQDVAEI----------- 311
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 219 gitlvrdydpSIPDLLidreQmiQAVLNIVRNAMQA---IAGQKHDMGLGR------ISLRTRTLRQFTIGHTRHRLVVK 289
Cdd:PRK10337 312 ----------PLEDLL----Q--SAVMDIYHTAQQAgidVRLTLNAHPVIRtgqpllLSLLVRNLLDNAIRYSPQGSVVD 375
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 2490585947 290 V-------EIIDNGPGIPPELQETI---FYPMVSGRADGTGLGLAITQNIISQHQ 334
Cdd:PRK10337 376 VtlnarnfTVRDNGPGVTPEALARIgerFYRPPGQEATGSGLGLSIVRRIAKLHG 430
|
|
| HATPase_YcbM-like |
cd16947 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
288-352 |
1.02e-04 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis YcbM; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Bacillus subtilis YcbM, a HK of the two-component system YcbM-YcbL. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA).
Pssm-ID: 340423 [Multi-domain] Cd Length: 125 Bit Score: 41.73 E-value: 1.02e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2490585947 288 VKVEIIDNGPGIPPELQETIF---YPMVSGRAD---GTGLGLAITQNIISQHQGLIECESHVGH-TVFSIFL 352
Cdd:cd16947 53 VYIDIWDKGKGISETEKDHVFerlYTLEDSRNSakqGNGLGLTITKRLAESMGGSIYVNSKPYEkTVFTVTL 124
|
|
| dpiB |
PRK15053 |
sensor histidine kinase DpiB; Provisional |
288-353 |
1.37e-04 |
|
sensor histidine kinase DpiB; Provisional
Pssm-ID: 185013 [Multi-domain] Cd Length: 545 Bit Score: 43.67 E-value: 1.37e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 288 VKVEIIDNGPGIPPELQETIFYPMVSGRADGT---GLGLAITQNIISQHQGLIECESHVGH-TVFSIFLP 353
Cdd:PRK15053 469 VVIEVADQGCGVPESLRDKIFEQGVSTRADEPgehGIGLYLIASYVTRCGGVITLEDNDPCgTLFSIFIP 538
|
|
| PRK11388 |
PRK11388 |
DNA-binding transcriptional regulator DhaR; Provisional |
7-116 |
3.46e-04 |
|
DNA-binding transcriptional regulator DhaR; Provisional
Pssm-ID: 183114 [Multi-domain] Cd Length: 638 Bit Score: 42.36 E-value: 3.46e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 7 HRLLLDNLTTATLLLNSKLCLEYMNPAAEMLLAVSGQRSHGQFISDLFTESPealsSLRQAVEQAHPFNKREAVLTSvtg 86
Cdd:PRK11388 205 LNALLESMDDGVIAWDEQGNLQFLNAQAARLLRLDATASQGRAITELLTLPA----VLQQAIKQAHPLKHVEVTFES--- 277
|
90 100 110
....*....|....*....|....*....|..
gi 2490585947 87 QTLTVDYAVT--PLFSKGETLLLLEVHPRDRL 116
Cdd:PRK11388 278 QGQFIDAVITlkPIIEGQGTSFILLLHPVEQM 309
|
|
| HATPase_BceS-YxdK-YvcQ-like |
cd16948 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
288-353 |
4.30e-04 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis BceS, YxdK, and Bacillus thuringiensis YvcQ; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Bacillus subtilis BceS and Bacillus thuringiensis YvcQ, the HKs of the two-component regulatory system (TCSs) BceS-BceR and YvcQ-YvcP, repsectively, which are both involved in regulating bacitracin resistance. It also includes the HATPase domain of YxdK, the HK of YxdK-YxdJ TCS involved in sensing antimicrobial compounds.
Pssm-ID: 340424 [Multi-domain] Cd Length: 109 Bit Score: 39.19 E-value: 4.30e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2490585947 288 VKVEIIDNGPGIPPELQETIFYPMVSG---RADG--TGLGLAITQNIISQ--HQglIECESHVGH-TVFSIFLP 353
Cdd:cd16948 38 VVLSIKDFGIGIPEEDLPRVFDKGFTGengRNFQesTGMGLYLVKKLCDKlgHK--IDVESEVGEgTTFTITFP 109
|
|
| PAS |
smart00091 |
PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising ... |
5-72 |
5.10e-04 |
|
PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels.
Pssm-ID: 214512 Cd Length: 67 Bit Score: 38.15 E-value: 5.10e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2490585947 5 ALHRLLLDNLTTATLLLNSKLCLEYMNPAAEMLLAVSGQRSHGQFISDLFteSPEALSSLRQAVEQAH 72
Cdd:smart00091 1 ERLRAILESLPDGIFVLDLDGRILYANPAAEELLGYSPEELIGKSLLELI--HPEDRERVQEALQRLL 66
|
|
| PRK10841 |
PRK10841 |
two-component system sensor histidine kinase RcsC; |
294-354 |
1.08e-03 |
|
two-component system sensor histidine kinase RcsC;
Pssm-ID: 182772 [Multi-domain] Cd Length: 924 Bit Score: 41.11 E-value: 1.08e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2490585947 294 DNGPGIPPELQETIFYPM------VSGRADGTGLGLAITQNIISQHQGLIECESHVG-HTVFSIFLPL 354
Cdd:PRK10841 600 DTGVGIPAKEVVRLFDPFfqvgtgVQRNFQGTGLGLAICEKLINMMDGDISVDSEPGmGSQFTIRIPL 667
|
|
| PAS |
pfam00989 |
PAS fold; The PAS fold corresponds to the structural domain that has previously been defined ... |
8-106 |
1.21e-03 |
|
PAS fold; The PAS fold corresponds to the structural domain that has previously been defined as PAS and PAC motifs. The PAS fold appears in archaea, eubacteria and eukarya. This domain can bind gases (O2, CO and NO), FAD, 4-hydroxycinnamic acid and NAD+ (Matilla et.al., FEMS Microbiology Reviews, fuab043, 45, 2021, 1. https://doi.org/10.1093/femsre/fuab043).
Pssm-ID: 395786 [Multi-domain] Cd Length: 113 Bit Score: 38.17 E-value: 1.21e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 8 RLLLDNLTTATLLLNSKLCLEYMNPAAEMLLAVSGQRSHGQFISDLFTE--SPEALSSLRQAVEQAHPFNKREAVLTSVT 85
Cdd:pfam00989 4 RAILESLPDGIFVVDEDGRILYVNAAAEELLGLSREEVIGKSLLDLIPEedDAEVAELLRQALLQGEESRGFEVSFRVPD 83
|
90 100
....*....|....*....|.
gi 2490585947 86 GQTLTVDYAVTPLFSKGETLL 106
Cdd:pfam00989 84 GRPRHVEVRASPVRDAGGEIL 104
|
|
| RocR |
COG3829 |
RocR-type transcriptional regulator, contains PAS, AAA-type ATPase, and DNA-binding Fis ... |
10-136 |
2.31e-03 |
|
RocR-type transcriptional regulator, contains PAS, AAA-type ATPase, and DNA-binding Fis domains [Transcription, Signal transduction mechanisms];
Pssm-ID: 443041 [Multi-domain] Cd Length: 448 Bit Score: 39.75 E-value: 2.31e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2490585947 10 LLDNLTTATLLLNSKLCLEYMNPAAEMLLAVSGQRSHGQFISDLFTESPealssLRQAVEQAHPFnkrEAVLTSVTGQTL 89
Cdd:COG3829 16 ILDSLDDGIIVVDADGRITYVNRAAERILGLPREEVIGKNVTELIPNSP-----LLEVLKTGKPV---TGVIQKTGGKGK 87
|
90 100 110 120
....*....|....*....|....*....|....*....|....*..
gi 2490585947 90 TVDYAVTPLFSKGETLLLLEVHpRDrLLRITKEEAQLSKQETTKLLV 136
Cdd:COG3829 88 TVIVTAIPIFEDGEVIGAVETF-RD-ITELKRLERKLREEELERGLS 132
|
|
| |
