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Conserved domains on  [gi|2438308169|gb|WCI18516|]
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cytochrome c biogenesis C (mitochondrion) [Vernicia fordii]

Protein Classification

heme lyase CcmF/NrfE family subunit( domain architecture ID 1562464)

heme lyase CcmF/NrfE family subunit such as Arabidopsis thaliana cytochrome c biogenesis CcmF N-terminal-like mitochondrial protein 1 that is involved in the assembly of heme with c-type apocytochromes

PubMed:  21958041|20382024

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
CcmF super family cl39128
Cytochrome c biogenesis protein CcmF [Energy production and conversion, Posttranslational ...
239-427 2.22e-11

Cytochrome c biogenesis protein CcmF [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


The actual alignment was detected with superfamily member COG1138:

Pssm-ID: 440753 [Multi-domain]  Cd Length: 650  Bit Score: 65.93  E-value: 2.22e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2438308169 239 MNISHGGVCICMLGVLLSNTKKIQFTQRLPLGSELHMGKERCCLRGLDHLHGPtshsicgnlmiykpsltndrlmfeHDE 318
Cdd:COG1138   492 MYLAHLGVAVTVIGIAGSSAYSVERDVRLAPGESVTLGGYTFTFEGVREVEGP------------------------NYT 547
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2438308169 319 SLRADLLLinfpasYENGKLEHflhrwmknrehknfwlTMFPEKRYFR-ETTSTTEVAIHTNLFTDLYASIGtGSSRTGG 397
Cdd:COG1138   548 AVRATFTV------SRDGKPVA----------------TLHPEKRFYPvRGMPTTEAAIDTGLLRDLYVVLG-EPLEDGA 604
                         170       180       190
                  ....*....|....*....|....*....|
gi 2438308169 398 WYTTIMKLPFLFFIRIGFMLASLGGSRSLL 427
Cdd:COG1138   605 WAVRVYYKPLVRWIWLGGLLMALGGLLALS 634
 
Name Accession Description Interval E-value
CcmF COG1138
Cytochrome c biogenesis protein CcmF [Energy production and conversion, Posttranslational ...
239-427 2.22e-11

Cytochrome c biogenesis protein CcmF [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440753 [Multi-domain]  Cd Length: 650  Bit Score: 65.93  E-value: 2.22e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2438308169 239 MNISHGGVCICMLGVLLSNTKKIQFTQRLPLGSELHMGKERCCLRGLDHLHGPtshsicgnlmiykpsltndrlmfeHDE 318
Cdd:COG1138   492 MYLAHLGVAVTVIGIAGSSAYSVERDVRLAPGESVTLGGYTFTFEGVREVEGP------------------------NYT 547
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2438308169 319 SLRADLLLinfpasYENGKLEHflhrwmknrehknfwlTMFPEKRYFR-ETTSTTEVAIHTNLFTDLYASIGtGSSRTGG 397
Cdd:COG1138   548 AVRATFTV------SRDGKPVA----------------TLHPEKRFYPvRGMPTTEAAIDTGLLRDLYVVLG-EPLEDGA 604
                         170       180       190
                  ....*....|....*....|....*....|
gi 2438308169 398 WYTTIMKLPFLFFIRIGFMLASLGGSRSLL 427
Cdd:COG1138   605 WAVRVYYKPLVRWIWLGGLLMALGGLLALS 634
CcmF_C pfam16327
Cytochrome c-type biogenesis protein CcmF C-terminal; This C-terminal region of CcmF, one of ...
239-422 2.10e-08

Cytochrome c-type biogenesis protein CcmF C-terminal; This C-terminal region of CcmF, one of the cytochrome c-type biogenesis proteins, is associated at the C-terminal with Cytochrome_C_asm family pfam01578. It is possible that it is this domain which delivers reductant to haem on CcmE.


Pssm-ID: 465096  Cd Length: 325  Bit Score: 55.56  E-value: 2.10e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2438308169 239 MNISHGGVCICMLGVLLSNTKKIQFTQRLPLGSELHMGKERCCLRGLDHLHGPtshsicgNlmiYKpsltndrlmfehde 318
Cdd:pfam16327 181 MVLAHLGVAVTVIGITLVSAYSVERDVRMAPGDTVELGGYTFTFDGVRPVQGP-------N---YT-------------- 236
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2438308169 319 SLRADLLLinfpasYENGKLEHflhrwmknrehknfwlTMFPEKRYFR-ETTSTTEVAIHTNLFTDLYASIGTGSSRtGG 397
Cdd:pfam16327 237 ADRGTFTV------TRDGKPVA----------------TLHPEKRFYPvQGMPMTEAAIDTGLTRDLYVALGEPLGD-GA 293
                         170       180
                  ....*....|....*....|....*...
gi 2438308169 398 WyttIMKL---PFLFFIRIGFMLASLGG 422
Cdd:pfam16327 294 W---AVRLyykPFVRWIWLGALLMALGG 318
 
Name Accession Description Interval E-value
CcmF COG1138
Cytochrome c biogenesis protein CcmF [Energy production and conversion, Posttranslational ...
239-427 2.22e-11

Cytochrome c biogenesis protein CcmF [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440753 [Multi-domain]  Cd Length: 650  Bit Score: 65.93  E-value: 2.22e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2438308169 239 MNISHGGVCICMLGVLLSNTKKIQFTQRLPLGSELHMGKERCCLRGLDHLHGPtshsicgnlmiykpsltndrlmfeHDE 318
Cdd:COG1138   492 MYLAHLGVAVTVIGIAGSSAYSVERDVRLAPGESVTLGGYTFTFEGVREVEGP------------------------NYT 547
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2438308169 319 SLRADLLLinfpasYENGKLEHflhrwmknrehknfwlTMFPEKRYFR-ETTSTTEVAIHTNLFTDLYASIGtGSSRTGG 397
Cdd:COG1138   548 AVRATFTV------SRDGKPVA----------------TLHPEKRFYPvRGMPTTEAAIDTGLLRDLYVVLG-EPLEDGA 604
                         170       180       190
                  ....*....|....*....|....*....|
gi 2438308169 398 WYTTIMKLPFLFFIRIGFMLASLGGSRSLL 427
Cdd:COG1138   605 WAVRVYYKPLVRWIWLGGLLMALGGLLALS 634
CcmF_C pfam16327
Cytochrome c-type biogenesis protein CcmF C-terminal; This C-terminal region of CcmF, one of ...
239-422 2.10e-08

Cytochrome c-type biogenesis protein CcmF C-terminal; This C-terminal region of CcmF, one of the cytochrome c-type biogenesis proteins, is associated at the C-terminal with Cytochrome_C_asm family pfam01578. It is possible that it is this domain which delivers reductant to haem on CcmE.


Pssm-ID: 465096  Cd Length: 325  Bit Score: 55.56  E-value: 2.10e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2438308169 239 MNISHGGVCICMLGVLLSNTKKIQFTQRLPLGSELHMGKERCCLRGLDHLHGPtshsicgNlmiYKpsltndrlmfehde 318
Cdd:pfam16327 181 MVLAHLGVAVTVIGITLVSAYSVERDVRMAPGDTVELGGYTFTFDGVRPVQGP-------N---YT-------------- 236
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2438308169 319 SLRADLLLinfpasYENGKLEHflhrwmknrehknfwlTMFPEKRYFR-ETTSTTEVAIHTNLFTDLYASIGTGSSRtGG 397
Cdd:pfam16327 237 ADRGTFTV------TRDGKPVA----------------TLHPEKRFYPvQGMPMTEAAIDTGLTRDLYVALGEPLGD-GA 293
                         170       180
                  ....*....|....*....|....*...
gi 2438308169 398 WyttIMKL---PFLFFIRIGFMLASLGG 422
Cdd:pfam16327 294 W---AVRLyykPFVRWIWLGALLMALGG 318
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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