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Conserved domains on  [gi|2427661520|gb|WBR78846|]
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NADH dehydrogenase subunit 6, partial (mitochondrion) [Aepyornis sp.]

Protein Classification

NADH dehydrogenase subunit 6( domain architecture ID 10009582)

NADH dehydrogenase subunit 6 (mitochondrion) is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND6 MTH00138
NADH dehydrogenase subunit 6; Provisional
 1-161 8.83e-50

NADH dehydrogenase subunit 6; Provisional


:

Pssm-ID: 177196  Cd Length: 173  Bit Score: 157.61  E-value: 8.83e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2427661520   1 FVLGALAVASNPSPYYGVLGLVVGSVIGCGWLLSLGVSFISLVLFLVYLGGMLVVFVYSVSLAADIFPETWGDWCV**** 80
Cdd:MTH00138   12 LVLGLVAVASNPSPYFAALGLVVVAGVGCGVLVGHGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPESWGSWSVLGYV 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2427661520  81 **************************DCGGAMSV-RLDFSGVAMFYSWGGGMFLIVGWGLLLTLFVVLELVRGLSRGTIR 159
Cdd:MTH00138   92 VGYLVGVVLAAGLFWGGWYEGSWVVVDELKEFSVlRGDVGGVALMYSSGGGMLVICAWVLLLTLFVVLELTRGLSRGALR 171


                  ..
gi 2427661520 160 AV 161
Cdd:MTH00138  172 AV 173
 
Name Accession Description Interval E-value
ND6 MTH00138
NADH dehydrogenase subunit 6; Provisional
 1-161 8.83e-50

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 177196  Cd Length: 173  Bit Score: 157.61  E-value: 8.83e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2427661520   1 FVLGALAVASNPSPYYGVLGLVVGSVIGCGWLLSLGVSFISLVLFLVYLGGMLVVFVYSVSLAADIFPETWGDWCV**** 80
Cdd:MTH00138   12 LVLGLVAVASNPSPYFAALGLVVVAGVGCGVLVGHGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPESWGSWSVLGYV 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2427661520  81 **************************DCGGAMSV-RLDFSGVAMFYSWGGGMFLIVGWGLLLTLFVVLELVRGLSRGTIR 159
Cdd:MTH00138   92 VGYLVGVVLAAGLFWGGWYEGSWVVVDELKEFSVlRGDVGGVALMYSSGGGMLVICAWVLLLTLFVVLELTRGLSRGALR 171


                  ..
gi 2427661520 160 AV 161
Cdd:MTH00138  172 AV 173
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
6-149 3.15e-09

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 52.51  E-value: 3.15e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2427661520   6 LAVASNPSPYYGVLGLVVGSVIGCGWLLSLGVSFISLVLFLVYLGGMLVVFVYSVSLAADIFPETWGDWcv********* 85
Cdd:pfam00499   1 LGVVTSRNPVHSALFLVLTFFGVAGLYLLLGAEFLAAVQVLVYVGAIMVLFLFVIMLLLAEEEPEKLRS--GLPLAALLL 78

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2427661520  86 *********************DCGGAMSVRLDFSGVAMFYSWgGGMFLIVGWGLLLTLFVVLEL 149
Cdd:pfam00499  79 GLLLLALLLLVLLSASLTPAAAAAAPDVGNIEAIGELLFTDY-LLPFELASVLLLVALVGAIVL 141
 
Name Accession Description Interval E-value
ND6 MTH00138
NADH dehydrogenase subunit 6; Provisional
 1-161 8.83e-50

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 177196  Cd Length: 173  Bit Score: 157.61  E-value: 8.83e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2427661520   1 FVLGALAVASNPSPYYGVLGLVVGSVIGCGWLLSLGVSFISLVLFLVYLGGMLVVFVYSVSLAADIFPETWGDWCV**** 80
Cdd:MTH00138   12 LVLGLVAVASNPSPYFAALGLVVVAGVGCGVLVGHGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPESWGSWSVLGYV 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2427661520  81 **************************DCGGAMSV-RLDFSGVAMFYSWGGGMFLIVGWGLLLTLFVVLELVRGLSRGTIR 159
Cdd:MTH00138   92 VGYLVGVVLAAGLFWGGWYEGSWVVVDELKEFSVlRGDVGGVALMYSSGGGMLVICAWVLLLTLFVVLELTRGLSRGALR 171


                  ..
gi 2427661520 160 AV 161
Cdd:MTH00138  172 AV 173
ND6 MTH00065
NADH dehydrogenase subunit 6; Provisional
 1-161 2.08e-45

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214415  Cd Length: 172  Bit Score: 146.53  E-value: 2.08e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2427661520   1 FVLGALAVASNPSPYYGVLGLVVGSVIGCGWLLSLGVSFISLVLFLVYLGGMLVVFVYSVSLAADIFPETWGDWCV**** 80
Cdd:MTH00065   12 LVVGLVAVASNPSPYFAALGLVLGAVCGCLVLVELGVSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPEAWGSWSVLVYV 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2427661520  81 **************************DCGGAMSVRLDFSGVAMFYSWGGGMFLIVGWGLLLTLFVVLELVRGLSRGTIRA 160
Cdd:MTH00065   92 LFYLLLLIVGYILFGCNFSLEFLFTNYDTEFSVVGYDWGGVGLMYSSGGWFLMISGWVLLLTLFVVLEVTRGLSRGSLRA 171


                  .
gi 2427661520 161 V 161
Cdd:MTH00065  172 V 172
ND6 MTH00115
NADH dehydrogenase subunit 6; Provisional
 1-161 7.59e-45

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214424  Cd Length: 174  Bit Score: 144.89  E-value: 7.59e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2427661520   1 FVLGALAVASNPSPYYGVLGLVVGSVIGCGWLLSLGVSFISLVLFLVYLGGMLVVFVYSVSLAADIFPETWGDW--CV** 78
Cdd:MTH00115   12 FVLGVVGVASNPSPYYGVVSLVLASVFGCGVLVSLGGSFVSLVLFLVYLGGMLVVFAYSVSLAADPYPEAWGDWgvVGYV 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2427661520  79 ****************************DCGGAMSVRLDFSGVAMFYSWGGGMFLIVGWGLLLTLFVVLELVRGLSRGTI 158
Cdd:MTH00115   92 VGFVLVVVVVGVVVGGLWGMEGVGVVTVDSGGLFVVRLDFSGVSLFYSSGGGGLLVCGWGLLLTLFVVLELVRGLSRGAL 171


                  ...
gi 2427661520 159 RAV 161
Cdd:MTH00115  172 RAF 174
ND6 MTH00109
NADH dehydrogenase subunit 6; Provisional
 1-152 2.18e-23

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214421  Cd Length: 175  Bit Score: 90.25  E-value: 2.18e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2427661520   1 FVLGALAVASNPSPYYGVLGLVVGSVIGCGWLLSLGVSFISLVLFLVYLGGMLVVFVYSVSLAADIFPETWGDWCV**** 80
Cdd:MTH00109   13 FVLGFVGFSSKPSPIYGGLGLIVSGGVGCGIVLSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEEYPETWVSNKVVLGA 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2427661520  81 **************************----------DCGGAMSVRLDFSGVAMFYSWGGGMFLIVGWGLLLTLFVVLELV 150
Cdd:MTH00109   93 LLLGLLMELLLVLYVLKDDEVEVVFNfnglgdwviyDTGGSGFFSEDAMGVAALYSYGTWLVVVTGWSLFIGVFVIIEIT 172


                  ..
gi 2427661520 151 RG 152
Cdd:MTH00109  173 RG 174
ND6 MTH00214
NADH dehydrogenase subunit 6; Provisional
 1-161 2.06e-22

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214461  Cd Length: 168  Bit Score: 87.35  E-value: 2.06e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2427661520   1 FVLGALAVASNPSPYYGVLGLVVGSVIGCGWLLSLGVSFISLVLFLVYLGGMLVVFVYSVSLAADIFPETWGDWCV**** 80
Cdd:MTH00214   12 FLLGLMMVASSPSPYFGALGLVLLALLGCFLLLSHGNSFLGLILFLIYLGGMLVVFSYSAALAADPYPESWGGWSVLLFF 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2427661520  81 **************************dcGGAMSVRLDFSGVAMFYSWGGGMFLIVGWGLLLTLFVVLELVRGLSRGTIRA 160
Cdd:MTH00214   92 LFYLLGLGFVGFYFYGGWEMLSWM----GVDEANNLDLSGVSDLYSRGFFLLLLGGVVLFLVLFVVLELVRGLSRGALRV 167


                  .
gi 2427661520 161 V 161
Cdd:MTH00214  168 V 168
ND6 MTH00045
NADH dehydrogenase subunit 6; Validated
 2-160 1.60e-15

NADH dehydrogenase subunit 6; Validated


Pssm-ID: 177120  Cd Length: 162  Bit Score: 69.55  E-value: 1.60e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2427661520   2 VLGALAVASNPSPYYGVLGLVVGSVIGCGWLLSLGVSFISLVLFLVYLGGMLVVFVYSVSLAADIFPetwgdwcv***** 81
Cdd:MTH00045   11 LFGSTLVFYSLSPYYSALGLVLVSLSGCLLLSLLGLSFLALLLLLIYMGGMLVVFVYSSALSAERYP--------SVSNL 82

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2427661520  82 *************************DCGGAMSVRLDFSGVAMFYSWGGGMFLIVGWGLLLTLFVVLELVRGLSRGTIRA 160
Cdd:MTH00045   83 GEVLVLSLLLSLWVFISFDNFLELSNNNWSLVSLSDLVGSSELYNSGGLYLLLGGFILLVALVVALVISFGHEYSSLRA 161
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
6-149 3.15e-09

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 52.51  E-value: 3.15e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2427661520   6 LAVASNPSPYYGVLGLVVGSVIGCGWLLSLGVSFISLVLFLVYLGGMLVVFVYSVSLAADIFPETWGDWcv********* 85
Cdd:pfam00499   1 LGVVTSRNPVHSALFLVLTFFGVAGLYLLLGAEFLAAVQVLVYVGAIMVLFLFVIMLLLAEEEPEKLRS--GLPLAALLL 78

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2427661520  86 *********************DCGGAMSVRLDFSGVAMFYSWgGGMFLIVGWGLLLTLFVVLEL 149
Cdd:pfam00499  79 GLLLLALLLLVLLSASLTPAAAAAAPDVGNIEAIGELLFTDY-LLPFELASVLLLVALVGAIVL 141
ND6 MTH00166
NADH dehydrogenase subunit 6; Provisional
 38-63 4.33e-03

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214445  Cd Length: 160  Bit Score: 35.55  E-value: 4.33e-03
                          10        20
                  ....*....|....*....|....*.
gi 2427661520  38 SFISLVLFLVYLGGMLVVFVYSVSLA 63
Cdd:MTH00166   46 FWFSYILFLIFLGGMLVLFIYITSLA 71
ND6 MTH00021
NADH dehydrogenase subunit 6; Validated
 2-62 5.03e-03

NADH dehydrogenase subunit 6; Validated


Pssm-ID: 214401 [Multi-domain]  Cd Length: 188  Bit Score: 35.86  E-value: 5.03e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2427661520   2 VLGALAVASNPSPYYGVLGLVVGSVIGCGWLLSLGVSFISLVLFLVYLGGMLVVFVYSVSL 62
Cdd:MTH00021    7 IGSGIMVISALNPVHSIFWLVVVFVNSAVFFILLGLDFLALMFLIIYVGAIAILFLFVIML 67
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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