NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1780586340|emb|VYS70894|]
View 

unnamed protein product [Arabidopsis thaliana]

Protein Classification

DMT family transporter( domain architecture ID 12093821)

DMT (drug/metabolite transporter) family transporter is an inner membrane protein involved in the transport of one or more of a variety of substrates such as amino acids, drugs, metabolites, and sugar phosphates, among others; such as yeast UDP-N-acetylglucosamine transporter YEA4 and vertebrate UDP-xylose and UDP-N-acetylglucosamine transporter

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
UAA pfam08449
UAA transporter family; This family includes transporters with a specificity for ...
 18-321 8.46e-96

UAA transporter family; This family includes transporters with a specificity for UDP-N-acetylglucosamine.


:

Pssm-ID: 462479 [Multi-domain]  Cd Length: 307  Bit Score: 286.50  E-value: 8.46e-96
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780586340  18 KGVFAVSGIMSTLVIYGVLQEKIMRVPYGvnkeffKHSLFLVFCNrltTSAVSAGALLASKKV------LDPVAPVYKYC 91
Cdd:pfam08449   1 QFLLAVSGVFGGCCSNGVLQELIMKVEPG------PFGNLLTFAQ---FLFYALEGLPESIDIftskflKPRKIPLKTYV 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780586340  92 LISVTNILTTTCQYEALKY-VSFPVQTLAKCAKMIPVMVWGTLIMQKKYKGFDYLVAFLVTLGCSVFILFPAGDDVSPYN 170
Cdd:pfam08449  72 ILVALFFITSVLNNEALKYdISYPTHIIFRSSKLIPVMIMGILILGKRYSKLQYLSAFLVTLGIIIFTLFSAKDKVADSV 151

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780586340 171 KGRENTVWGVSLMAGYLGFDGFTSTFQDKLFKGYNMEIHNQIFYTTLCSCVLSFtglILQGHLLPAVDFVSLHRDC---- 246
Cdd:pfam08449 152 VSPNFFLIGIAMLSGALLLDAFLGNYQEKTYKKYGKHSKEMLFYSHLLSLPFFL---LLQGDLFSAVQFCSQSPDKavls 228

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1780586340 247 ----LLDIALLSTVATASQFFISYTIRTFGALTFAAIMTTRQLASIMLSCIWFSHPLSWEQCIGSVIVFGSLYAKNLLN 321
Cdd:pfam08449 229 lpsmLFYLLLNVLTQYVCIRGVFILISEFGALTVTLVTTLRKFVSLLLSILLFGNPFTLQHWVGTLLVFLGTFLYSYSK 307
 
Name Accession Description Interval E-value
UAA pfam08449
UAA transporter family; This family includes transporters with a specificity for ...
 18-321 8.46e-96

UAA transporter family; This family includes transporters with a specificity for UDP-N-acetylglucosamine.


Pssm-ID: 462479 [Multi-domain]  Cd Length: 307  Bit Score: 286.50  E-value: 8.46e-96
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780586340  18 KGVFAVSGIMSTLVIYGVLQEKIMRVPYGvnkeffKHSLFLVFCNrltTSAVSAGALLASKKV------LDPVAPVYKYC 91
Cdd:pfam08449   1 QFLLAVSGVFGGCCSNGVLQELIMKVEPG------PFGNLLTFAQ---FLFYALEGLPESIDIftskflKPRKIPLKTYV 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780586340  92 LISVTNILTTTCQYEALKY-VSFPVQTLAKCAKMIPVMVWGTLIMQKKYKGFDYLVAFLVTLGCSVFILFPAGDDVSPYN 170
Cdd:pfam08449  72 ILVALFFITSVLNNEALKYdISYPTHIIFRSSKLIPVMIMGILILGKRYSKLQYLSAFLVTLGIIIFTLFSAKDKVADSV 151

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780586340 171 KGRENTVWGVSLMAGYLGFDGFTSTFQDKLFKGYNMEIHNQIFYTTLCSCVLSFtglILQGHLLPAVDFVSLHRDC---- 246
Cdd:pfam08449 152 VSPNFFLIGIAMLSGALLLDAFLGNYQEKTYKKYGKHSKEMLFYSHLLSLPFFL---LLQGDLFSAVQFCSQSPDKavls 228

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1780586340 247 ----LLDIALLSTVATASQFFISYTIRTFGALTFAAIMTTRQLASIMLSCIWFSHPLSWEQCIGSVIVFGSLYAKNLLN 321
Cdd:pfam08449 229 lpsmLFYLLLNVLTQYVCIRGVFILISEFGALTVTLVTTLRKFVSLLLSILLFGNPFTLQHWVGTLLVFLGTFLYSYSK 307
RhaT COG0697
Permease of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and ...
 97-315 4.70e-03

Permease of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism, Amino acid transport and metabolism, General function prediction only];


Pssm-ID: 440461 [Multi-domain]  Cd Length: 290  Bit Score: 38.28  E-value: 4.70e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780586340  97 NILTTTCQYEALKYVSFPVQTLakCAKMIPVMV--WGTLIMQKKYKGFDYLVAFLVTLGCsVFILFPAGDDVSPYNKGre 174
Cdd:COG0697    76 LALAFLLFFLALQYTPAALAAL--LLALAPLFValLAALLLGERLSRRRWLGLLLGFAGV-LLIVGPGGGGGGGSLLG-- 150

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780586340 175 nTVWGVSLMAGYlgfdGFTSTFQDKLFKGYNMEihNQIFYTTLCSCVLSFTGLILQGHLLPavdfvsLHRDCLLDIALLS 254
Cdd:COG0697   151 -DLLALLAALSW----ALYTVLTRRLSRRLDPL--TLTFWQMLVGALLLLPLALLTGLPLP------LSAAAWLALLYLG 217

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1780586340 255 TVATA-SQFFISYTIRTFGALTFAAIMTTRQLASIMLSCIWFSHPLSWEQCIGSVIVFGSLY 315
Cdd:COG0697   218 LFGTAlAYLLWFRALRRLGASRAAPLTYLEPVFAVLLGWLLLGEPLTPLQLLGAALILAGVL 279
 
Name Accession Description Interval E-value
UAA pfam08449
UAA transporter family; This family includes transporters with a specificity for ...
 18-321 8.46e-96

UAA transporter family; This family includes transporters with a specificity for UDP-N-acetylglucosamine.


Pssm-ID: 462479 [Multi-domain]  Cd Length: 307  Bit Score: 286.50  E-value: 8.46e-96
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780586340  18 KGVFAVSGIMSTLVIYGVLQEKIMRVPYGvnkeffKHSLFLVFCNrltTSAVSAGALLASKKV------LDPVAPVYKYC 91
Cdd:pfam08449   1 QFLLAVSGVFGGCCSNGVLQELIMKVEPG------PFGNLLTFAQ---FLFYALEGLPESIDIftskflKPRKIPLKTYV 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780586340  92 LISVTNILTTTCQYEALKY-VSFPVQTLAKCAKMIPVMVWGTLIMQKKYKGFDYLVAFLVTLGCSVFILFPAGDDVSPYN 170
Cdd:pfam08449  72 ILVALFFITSVLNNEALKYdISYPTHIIFRSSKLIPVMIMGILILGKRYSKLQYLSAFLVTLGIIIFTLFSAKDKVADSV 151

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780586340 171 KGRENTVWGVSLMAGYLGFDGFTSTFQDKLFKGYNMEIHNQIFYTTLCSCVLSFtglILQGHLLPAVDFVSLHRDC---- 246
Cdd:pfam08449 152 VSPNFFLIGIAMLSGALLLDAFLGNYQEKTYKKYGKHSKEMLFYSHLLSLPFFL---LLQGDLFSAVQFCSQSPDKavls 228

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1780586340 247 ----LLDIALLSTVATASQFFISYTIRTFGALTFAAIMTTRQLASIMLSCIWFSHPLSWEQCIGSVIVFGSLYAKNLLN 321
Cdd:pfam08449 229 lpsmLFYLLLNVLTQYVCIRGVFILISEFGALTVTLVTTLRKFVSLLLSILLFGNPFTLQHWVGTLLVFLGTFLYSYSK 307
RhaT COG0697
Permease of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and ...
 97-315 4.70e-03

Permease of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism, Amino acid transport and metabolism, General function prediction only];


Pssm-ID: 440461 [Multi-domain]  Cd Length: 290  Bit Score: 38.28  E-value: 4.70e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780586340  97 NILTTTCQYEALKYVSFPVQTLakCAKMIPVMV--WGTLIMQKKYKGFDYLVAFLVTLGCsVFILFPAGDDVSPYNKGre 174
Cdd:COG0697    76 LALAFLLFFLALQYTPAALAAL--LLALAPLFValLAALLLGERLSRRRWLGLLLGFAGV-LLIVGPGGGGGGGSLLG-- 150

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780586340 175 nTVWGVSLMAGYlgfdGFTSTFQDKLFKGYNMEihNQIFYTTLCSCVLSFTGLILQGHLLPavdfvsLHRDCLLDIALLS 254
Cdd:COG0697   151 -DLLALLAALSW----ALYTVLTRRLSRRLDPL--TLTFWQMLVGALLLLPLALLTGLPLP------LSAAAWLALLYLG 217

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1780586340 255 TVATA-SQFFISYTIRTFGALTFAAIMTTRQLASIMLSCIWFSHPLSWEQCIGSVIVFGSLY 315
Cdd:COG0697   218 LFGTAlAYLLWFRALRRLGASRAAPLTYLEPVFAVLLGWLLLGEPLTPLQLLGAALILAGVL 279
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH