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Conserved domains on  [gi|1780599528|emb|VYS54442|]
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unnamed protein product [Arabidopsis thaliana]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
RecA-like_VPS4-like cd19509
ATPase domain of VPS4, ATAD1, K, KTNA1, Spastin, FIGL-1 and similar ATPase domains; This ...
 114-278 1.60e-87

ATPase domain of VPS4, ATAD1, K, KTNA1, Spastin, FIGL-1 and similar ATPase domains; This subfamily includes the ATPase domains of vacuolar protein sorting-associated protein 4 (VPS4), ATPase family AAA domain-containing protein 1 (ATAD1, also known as Thorase), Katanin p60 ATPase-containing subunit A1 (KTNA1), Spastin, and Fidgetin-Like 1 (FIGL-1). This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


:

Pssm-ID: 410917 [Multi-domain]  Cd Length: 163  Bit Score: 261.90  E-value: 1.60e-87
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528 114 IKGLENAKKLLKEAVVMPIKYPTYFNGLLTPWKGILLFGPPGTGKTMLAKAVATECNTTFFNISASSVVSKWRGDSEKLI 193
Cdd:cd19509     1 IAGLDDAKEALKEAVILPSLRPDLFPGLRGPPRGILLYGPPGTGKTLLARAVASESGSTFFSISASSLVSKWVGESEKIV 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528 194 RVLFDLARHHAPSTIFLDEIDAIISQRggeGRSEHEASRRLKTELLIQMDGLQ-KTNELVFVLAATNLPWELDAAMLRRL 272
Cdd:cd19509    81 RALFALARELQPSIIFIDEIDSLLSER---GSGEHEASRRVKTEFLVQMDGVLnKPEDRVLVLGATNRPWELDEAFLRRF 157


                  ....*.
gi 1780599528 273 EKRILV 278
Cdd:cd19509   158 EKRIYI 163
AAA_lid_3 pfam17862
AAA+ lid domain; This entry represents the alpha helical AAA+ lid domain that is found to the ...
 306-343 2.00e-08

AAA+ lid domain; This entry represents the alpha helical AAA+ lid domain that is found to the C-terminus of AAA domains.


:

Pssm-ID: 465537 [Multi-domain]  Cd Length: 45  Bit Score: 49.84  E-value: 2.00e-08
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 1780599528 306 DVLVEKSEGYSGSDIRILCKEAAMQPLRRTLAILEDRE 343
Cdd:pfam17862   5 EELAERTEGFSGADLEALCREAALAALRRGLEAVTQED 42
 
Name Accession Description Interval E-value
RecA-like_VPS4-like cd19509
ATPase domain of VPS4, ATAD1, K, KTNA1, Spastin, FIGL-1 and similar ATPase domains; This ...
 114-278 1.60e-87

ATPase domain of VPS4, ATAD1, K, KTNA1, Spastin, FIGL-1 and similar ATPase domains; This subfamily includes the ATPase domains of vacuolar protein sorting-associated protein 4 (VPS4), ATPase family AAA domain-containing protein 1 (ATAD1, also known as Thorase), Katanin p60 ATPase-containing subunit A1 (KTNA1), Spastin, and Fidgetin-Like 1 (FIGL-1). This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410917 [Multi-domain]  Cd Length: 163  Bit Score: 261.90  E-value: 1.60e-87
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528 114 IKGLENAKKLLKEAVVMPIKYPTYFNGLLTPWKGILLFGPPGTGKTMLAKAVATECNTTFFNISASSVVSKWRGDSEKLI 193
Cdd:cd19509     1 IAGLDDAKEALKEAVILPSLRPDLFPGLRGPPRGILLYGPPGTGKTLLARAVASESGSTFFSISASSLVSKWVGESEKIV 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528 194 RVLFDLARHHAPSTIFLDEIDAIISQRggeGRSEHEASRRLKTELLIQMDGLQ-KTNELVFVLAATNLPWELDAAMLRRL 272
Cdd:cd19509    81 RALFALARELQPSIIFIDEIDSLLSER---GSGEHEASRRVKTEFLVQMDGVLnKPEDRVLVLGATNRPWELDEAFLRRF 157


                  ....*.
gi 1780599528 273 EKRILV 278
Cdd:cd19509   158 EKRIYI 163
RPT1 COG1222
ATP-dependent 26S proteasome regulatory subunit [Posttranslational modification, protein ...
 107-349 7.56e-84

ATP-dependent 26S proteasome regulatory subunit [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440835 [Multi-domain]  Cd Length: 326  Bit Score: 258.78  E-value: 7.56e-84
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528 107 PNIKWESIKGLENAKKLLKEAVVMPIKYPTYFN--GLLTPwKGILLFGPPGTGKTMLAKAVATECNTTFFNISASSVVSK 184
Cdd:COG1222    73 PDVTFDDIGGLDEQIEEIREAVELPLKNPELFRkyGIEPP-KGVLLYGPPGTGKTLLAKAVAGELGAPFIRVRGSELVSK 151

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528 185 WRGDSEKLIRVLFDLARHHAPSTIFLDEIDAIISQRGGEGrsEHEASRRLKTELLIQMDGLQKTNElVFVLAATNLPWEL 264
Cdd:COG1222   152 YIGEGARNVREVFELAREKAPSIIFIDEIDAIAARRTDDG--TSGEVQRTVNQLLAELDGFESRGD-VLIIAATNRPDLL 228

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528 265 DAAMLR--RLEKRILVPLPDPEARRGMFEMLIPSQPGDEPLPHDVLVEKSEGYSGSDIRILCKEAAMqplrrtLAILEDR 342
Cdd:COG1222   229 DPALLRpgRFDRVIEVPLPDEEAREEILKIHLRDMPLADDVDLDKLAKLTEGFSGADLKAIVTEAGM------FAIREGR 302


                  ....*..
gi 1780599528 343 EDVVPED 349
Cdd:COG1222   303 DTVTMED 309
CDC48 TIGR01243
AAA family ATPase, CDC48 subfamily; This subfamily of the AAA family ATPases includes two ...
 97-388 1.60e-68

AAA family ATPase, CDC48 subfamily; This subfamily of the AAA family ATPases includes two members each from three archaeal species. It also includes yeast CDC48 (cell division control protein 48) and the human ortholog, transitional endoplasmic reticulum ATPase (valosin-containing protein). These proteins in eukaryotes are involved in the budding and transfer of membrane from the transitional endoplasmic reticulum to the Golgi apparatus.


Pssm-ID: 273521 [Multi-domain]  Cd Length: 733  Bit Score: 229.79  E-value: 1.60e-68
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528  97 SLSRDIIRGNPNIKWESIKGLENAKKLLKEAVVMPIKYPTYFNGL-LTPWKGILLFGPPGTGKTMLAKAVATECNTTFFN 175
Cdd:TIGR01243 438 SAIREVLVEVPNVRWSDIGGLEEVKQELREAVEWPLKHPEIFEKMgIRPPKGVLLFGPPGTGKTLLAKAVATESGANFIA 517

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528 176 ISASSVVSKWRGDSEKLIRVLFDLARHHAPSTIFLDEIDAIISQRggeGRSEHEA-SRRLKTELLIQMDGLQKTNELVfV 254
Cdd:TIGR01243 518 VRGPEILSKWVGESEKAIREIFRKARQAAPAIIFFDEIDAIAPAR---GARFDTSvTDRIVNQLLTEMDGIQELSNVV-V 593

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528 255 LAATNLPWELDAAMLR--RLEKRILVPLPDPEARRGMFEMLIPSQPGDEPLPHDVLVEKSEGYSGSDIRILCKEAAMQPL 332
Cdd:TIGR01243 594 IAATNRPDILDPALLRpgRFDRLILVPPPDEEARKEIFKIHTRSMPLAEDVDLEELAEMTEGYTGADIEAVCREAAMAAL 673

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1780599528 333 RRTLAILEDREDVVPEDELPKIGPILPEDIDRALSNTRPSAHLHAHL-YDKFNDDYG 388
Cdd:TIGR01243 674 RESIGSPAKEKLEVGEEEFLKDLKVEMRHFLEALKKVKPSVSKEDMLrYERLAKELK 730
cell_div_CdvC NF041006
cell division protein CdvC;
85-372 9.18e-66

cell division protein CdvC;


Pssm-ID: 468935 [Multi-domain]  Cd Length: 371  Bit Score: 213.44  E-value: 9.18e-66
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528  85 PFESAETRTLAESLSRDIIRGNPNIKWESIKGLENAKKLLKEAVVMPIKYPTYFnglltP--W-KGILLFGPPGTGKTML 161
Cdd:NF041006   76 PAEPAGPDVEKESDEELVVKEKPKVTFSDIVGLEDVKEALKEAIVYPSKRPDLF-----PlgWpRGILLYGPPGCGKTML 150

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528 162 AKAVATECNTTFFNISASSVVSKWRGDSEKLIRVLFDLARHHA-----PSTIFLDEIDAII----SQRGGEGrseheasr 232
Cdd:NF041006  151 AAAVANEIDSEFIHVDAASIMSKWLGEAEKNVAKIFKKAREKSkeegkPAIIFIDEIDALLgvysSEVGGEV-------- 222

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528 233 RLKTELLIQMDGLQKTNEL--VFVLAATNLPWELDAAMLRRLEKRILVPLPDPEARRGMFEMLIPSQPGDEPLPHDVLVE 310
Cdd:NF041006  223 RVRNQFLKEMDGLQDKSENyhVYVIGATNKPWRLDEPFLRRFQKRIYIPLPDREQRLELLKYYTSKIKLENDVDLDELAE 302

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1780599528 311 KSEGYSGSDIRILCKEAAMqplrRTLAILEDREDVVPEdelpkigPILPEDIDRALSNTRPS 372
Cdd:NF041006  303 MTEGYTASDIRDIVQAAHM----RVVKEMFEKGLGEPR-------PITMEDFKEVLKIRKPS 353
PRK03992 PRK03992
proteasome-activating nucleotidase; Provisional
 107-349 1.15e-59

proteasome-activating nucleotidase; Provisional


Pssm-ID: 179699 [Multi-domain]  Cd Length: 389  Bit Score: 198.13  E-value: 1.15e-59
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528 107 PNIKWESIKGLENAKKLLKEAVVMPIKYPTYFNGL-LTPWKGILLFGPPGTGKTMLAKAVATECNTTFFNISASSVVSKW 185
Cdd:PRK03992  126 PNVTYEDIGGLEEQIREVREAVELPLKKPELFEEVgIEPPKGVLLYGPPGTGKTLLAKAVAHETNATFIRVVGSELVQKF 205

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528 186 RGDSEKLIRVLFDLARHHAPSTIFLDEIDAIISQRGGEGRS-EHEASRRLkTELLIQMDGLQKTNElVFVLAATNLPWEL 264
Cdd:PRK03992  206 IGEGARLVRELFELAREKAPSIIFIDEIDAIAAKRTDSGTSgDREVQRTL-MQLLAEMDGFDPRGN-VKIIAATNRIDIL 283

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528 265 DAAMLR--RLEKRILVPLPDPEARRGMFEmlIPSQpgDEPLPHDV----LVEKSEGYSGSDIRILCKEAAMqplrrtLAI 338
Cdd:PRK03992  284 DPAILRpgRFDRIIEVPLPDEEGRLEILK--IHTR--KMNLADDVdleeLAELTEGASGADLKAICTEAGM------FAI 353

                         250
                  ....*....|.
gi 1780599528 339 LEDREDVVPED 349
Cdd:PRK03992  354 RDDRTEVTMED 364
AAA pfam00004
ATPase family associated with various cellular activities (AAA); AAA family proteins often ...
 148-280 2.58e-55

ATPase family associated with various cellular activities (AAA); AAA family proteins often perform chaperone-like functions that assist in the assembly, operation, or disassembly of protein complexes.


Pssm-ID: 459627 [Multi-domain]  Cd Length: 130  Bit Score: 178.17  E-value: 2.58e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528 148 ILLFGPPGTGKTMLAKAVATECNTTFFNISASSVVSKWRGDSEKLIRVLFDLARHHAPSTIFLDEIDAIISQRggeGRSE 227
Cdd:pfam00004   1 LLLYGPPGTGKTTLAKAVAKELGAPFIEISGSELVSKYVGESEKRLRELFEAAKKLAPCVIFIDEIDALAGSR---GSGG 77

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1780599528 228 HEASRRLKTELLIQMDGLQKTNELVFVLAATNLPWELDAAMLRRLEKRILVPL 280
Cdd:pfam00004  78 DSESRRVVNQLLTELDGFTSSNSKVIVIAATNRPDKLDPALLGRFDRIIEFPL 130
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
 144-282 2.19e-16

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 75.49  E-value: 2.19e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528  144 PWKGILLFGPPGTGKTMLAKAVATECNTT---FFNISAS--------------SVVSKWRGDSEKLIRVLFDLARHHAPS 206
Cdd:smart00382   1 PGEVILIVGPPGSGKTTLARALARELGPPgggVIYIDGEdileevldqllliiVGGKKASGSGELRLRLALALARKLKPD 80

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1780599528  207 TIFLDEIDAIIsqrggegRSEHEASRRLKTELLIQMDGLQKTNELVfVLAATNLPWELDAAMLRRLEKRILVPLPD 282
Cdd:smart00382  81 VLILDEITSLL-------DAEQEALLLLLEELRLLLLLKSEKNLTV-ILTTNDEKDLGPALLRRRFDRRIVLLLIL 148
AAA_lid_3 pfam17862
AAA+ lid domain; This entry represents the alpha helical AAA+ lid domain that is found to the ...
 306-343 2.00e-08

AAA+ lid domain; This entry represents the alpha helical AAA+ lid domain that is found to the C-terminus of AAA domains.


Pssm-ID: 465537 [Multi-domain]  Cd Length: 45  Bit Score: 49.84  E-value: 2.00e-08
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 1780599528 306 DVLVEKSEGYSGSDIRILCKEAAMQPLRRTLAILEDRE 343
Cdd:pfam17862   5 EELAERTEGFSGADLEALCREAALAALRRGLEAVTQED 42
IS21_help_AAA NF038214
IS21-like element helper ATPase IstB; This protein family model resembles PF01695, but was ...
 148-169 5.88e-03

IS21-like element helper ATPase IstB; This protein family model resembles PF01695, but was built to hit full-length AAA+ ATPases of IS21 family IS (insertion sequence) elements.


Pssm-ID: 439516  Cd Length: 232  Bit Score: 37.84  E-value: 5.88e-03
                          10        20
                  ....*....|....*....|..
gi 1780599528 148 ILLFGPPGTGKTMLAKAVATEC 169
Cdd:NF038214   93 VLLLGPPGTGKTHLAIALGYAA 114
 
Name Accession Description Interval E-value
RecA-like_VPS4-like cd19509
ATPase domain of VPS4, ATAD1, K, KTNA1, Spastin, FIGL-1 and similar ATPase domains; This ...
 114-278 1.60e-87

ATPase domain of VPS4, ATAD1, K, KTNA1, Spastin, FIGL-1 and similar ATPase domains; This subfamily includes the ATPase domains of vacuolar protein sorting-associated protein 4 (VPS4), ATPase family AAA domain-containing protein 1 (ATAD1, also known as Thorase), Katanin p60 ATPase-containing subunit A1 (KTNA1), Spastin, and Fidgetin-Like 1 (FIGL-1). This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410917 [Multi-domain]  Cd Length: 163  Bit Score: 261.90  E-value: 1.60e-87
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528 114 IKGLENAKKLLKEAVVMPIKYPTYFNGLLTPWKGILLFGPPGTGKTMLAKAVATECNTTFFNISASSVVSKWRGDSEKLI 193
Cdd:cd19509     1 IAGLDDAKEALKEAVILPSLRPDLFPGLRGPPRGILLYGPPGTGKTLLARAVASESGSTFFSISASSLVSKWVGESEKIV 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528 194 RVLFDLARHHAPSTIFLDEIDAIISQRggeGRSEHEASRRLKTELLIQMDGLQ-KTNELVFVLAATNLPWELDAAMLRRL 272
Cdd:cd19509    81 RALFALARELQPSIIFIDEIDSLLSER---GSGEHEASRRVKTEFLVQMDGVLnKPEDRVLVLGATNRPWELDEAFLRRF 157


                  ....*.
gi 1780599528 273 EKRILV 278
Cdd:cd19509   158 EKRIYI 163
RecA-like_KTNA1 cd19522
Katanin p60 ATPase-containing subunit A1; Katanin p60 ATPase-containing subunit A1 (KTNA1) is ...
 114-278 3.94e-87

Katanin p60 ATPase-containing subunit A1; Katanin p60 ATPase-containing subunit A1 (KTNA1) is the catalytic subunit of the Katanin complex which is severs microtubules in an ATP-dependent manner, and is implicated in multiple aspects of microtubule dynamics. In addition to the p60 catalytic ATPase subunit, Katanin contains an accessory subunit (p80 or p80-like). The microtubule-severing activity of the ATPase is essential for female meiotic spindle assembly, and male gamete production; and the katanin complex severing microtubules is under tight regulation during the transition from the meiotic to mitotic stage to allow proper embryogenesis. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410930 [Multi-domain]  Cd Length: 170  Bit Score: 261.46  E-value: 3.94e-87
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528 114 IKGLENAKKLLKEAVVMPIKYPTYFNGLLTPWKGILLFGPPGTGKTMLAKAVATECNTTFFNISASSVVSKWRGDSEKLI 193
Cdd:cd19522     2 IADLEEAKKLLEEAVVLPMWMPEFFKGIRRPWKGVLMVGPPGTGKTLLAKAVATECGTTFFNVSSSTLTSKYRGESEKLV 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528 194 RVLFDLARHHAPSTIFLDEIDAIISQRGGEgrSEHEASRRLKTELLIQMDGLQKTNE------LVFVLAATNLPWELDAA 267
Cdd:cd19522    82 RLLFEMARFYAPTTIFIDEIDSICSRRGTS--EEHEASRRVKSELLVQMDGVGGASEnddpskMVMVLAATNFPWDIDEA 159

                         170
                  ....*....|.
gi 1780599528 268 MLRRLEKRILV 278
Cdd:cd19522   160 LRRRLEKRIYI 170
RPT1 COG1222
ATP-dependent 26S proteasome regulatory subunit [Posttranslational modification, protein ...
 107-349 7.56e-84

ATP-dependent 26S proteasome regulatory subunit [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440835 [Multi-domain]  Cd Length: 326  Bit Score: 258.78  E-value: 7.56e-84
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528 107 PNIKWESIKGLENAKKLLKEAVVMPIKYPTYFN--GLLTPwKGILLFGPPGTGKTMLAKAVATECNTTFFNISASSVVSK 184
Cdd:COG1222    73 PDVTFDDIGGLDEQIEEIREAVELPLKNPELFRkyGIEPP-KGVLLYGPPGTGKTLLAKAVAGELGAPFIRVRGSELVSK 151

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528 185 WRGDSEKLIRVLFDLARHHAPSTIFLDEIDAIISQRGGEGrsEHEASRRLKTELLIQMDGLQKTNElVFVLAATNLPWEL 264
Cdd:COG1222   152 YIGEGARNVREVFELAREKAPSIIFIDEIDAIAARRTDDG--TSGEVQRTVNQLLAELDGFESRGD-VLIIAATNRPDLL 228

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528 265 DAAMLR--RLEKRILVPLPDPEARRGMFEMLIPSQPGDEPLPHDVLVEKSEGYSGSDIRILCKEAAMqplrrtLAILEDR 342
Cdd:COG1222   229 DPALLRpgRFDRVIEVPLPDEEAREEILKIHLRDMPLADDVDLDKLAKLTEGFSGADLKAIVTEAGM------FAIREGR 302


                  ....*..
gi 1780599528 343 EDVVPED 349
Cdd:COG1222   303 DTVTMED 309
RecA-like_VPS4 cd19521
ATPase domain of vacuolar protein sorting-associated protein 4; Vacuolar protein ...
 107-278 9.40e-81

ATPase domain of vacuolar protein sorting-associated protein 4; Vacuolar protein sorting-associated protein 4 (Vps4) is believed to be involved in intracellular protein transport out of a prevacuolar endosomal compartment. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410929 [Multi-domain]  Cd Length: 170  Bit Score: 245.16  E-value: 9.40e-81
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528 107 PNIKWESIKGLENAKKLLKEAVVMPIKYPTYFNGLLTPWKGILLFGPPGTGKTMLAKAVATECNTTFFNISASSVVSKWR 186
Cdd:cd19521     2 PNVKWEDVAGLEGAKEALKEAVILPVKFPHLFTGNRKPWSGILLYGPPGTGKSYLAKAVATEANSTFFSVSSSDLVSKWM 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528 187 GDSEKLIRVLFDLARHHAPSTIFLDEIDAIISQRggeGRSEHEASRRLKTELLIQMDGLQKTNELVFVLAATNLPWELDA 266
Cdd:cd19521    82 GESEKLVKQLFAMARENKPSIIFIDEVDSLCGTR---GEGESEASRRIKTELLVQMNGVGNDSQGVLVLGATNIPWQLDS 158

                         170
                  ....*....|..
gi 1780599528 267 AMLRRLEKRILV 278
Cdd:cd19521   159 AIRRRFEKRIYI 170
RecA-like_Figl-1 cd19525
ATPase domain of Fidgetin-Like 1 (FIGL-1); FIGL-1 may participate in DNA repair in the nucleus; ...
 94-278 1.48e-69

ATPase domain of Fidgetin-Like 1 (FIGL-1); FIGL-1 may participate in DNA repair in the nucleus; it may be involved in DNA double-strand break repair via homologous recombination. Caenorhabditis elegans FIGL-1 is a nuclear protein and controls the mitotic progression in the germ line and mouse FIGL-1 may be involved in the control of male meiosis. human FIGL-1 has been shown to be a centrosome protein involved in ciliogenesis perhaps as a microtubule-severing protein. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410933 [Multi-domain]  Cd Length: 186  Bit Score: 217.16  E-value: 1.48e-69
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528  94 LAESLSRDIIRGNPNIKWESIKGLENAKKLLKEAVVMPIKYPTYFNGLLTPWKGILLFGPPGTGKTMLAKAVATECNTTF 173
Cdd:cd19525     4 MIELIMSEIMDHGPPINWADIAGLEFAKKTIKEIVVWPMLRPDIFTGLRGPPKGILLFGPPGTGKTLIGKCIASQSGATF 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528 174 FNISASSVVSKWRGDSEKLIRVLFDLARHHAPSTIFLDEIDAIISQRggeGRSEHEASRRLKTELLIQMDGLQKT-NELV 252
Cdd:cd19525    84 FSISASSLTSKWVGEGEKMVRALFSVARCKQPAVIFIDEIDSLLSQR---GEGEHESSRRIKTEFLVQLDGATTSsEDRI 160

                         170       180
                  ....*....|....*....|....*.
gi 1780599528 253 FVLAATNLPWELDAAMLRRLEKRILV 278
Cdd:cd19525   161 LVVGATNRPQEIDEAARRRLVKRLYI 186
SpoVK COG0464
AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle ...
 111-349 1.74e-69

AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];


Pssm-ID: 440232 [Multi-domain]  Cd Length: 397  Bit Score: 224.02  E-value: 1.74e-69
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528 111 WESIKGLENAKKLLKEAVVMPIKYPTYFNGL-LTPWKGILLFGPPGTGKTMLAKAVATECNTTFFNISASSVVSKWRGDS 189
Cdd:COG0464   156 LDDLGGLEEVKEELRELVALPLKRPELREEYgLPPPRGLLLYGPPGTGKTLLARALAGELGLPLIEVDLSDLVSKYVGET 235

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528 190 EKLIRVLFDLARHHAPSTIFLDEIDAIISQRGGEGrseHEASRRLKTELLIQMDGLQKTnelVFVLAATNLPWELDAAML 269
Cdd:COG0464   236 EKNLREVFDKARGLAPCVLFIDEADALAGKRGEVG---DGVGRRVVNTLLTEMEELRSD---VVVIAATNRPDLLDPALL 309

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528 270 RRLEKRILVPLPDPEARRGMFEMLIPSQPGDEPLPHDVLVEKSEGYSGSDIRILCKEAAMQplrrtlAILEDREDVVPED 349
Cdd:COG0464   310 RRFDEIIFFPLPDAEERLEIFRIHLRKRPLDEDVDLEELAEATEGLSGADIRNVVRRAALQ------ALRLGREPVTTED 383
CDC48 TIGR01243
AAA family ATPase, CDC48 subfamily; This subfamily of the AAA family ATPases includes two ...
 97-388 1.60e-68

AAA family ATPase, CDC48 subfamily; This subfamily of the AAA family ATPases includes two members each from three archaeal species. It also includes yeast CDC48 (cell division control protein 48) and the human ortholog, transitional endoplasmic reticulum ATPase (valosin-containing protein). These proteins in eukaryotes are involved in the budding and transfer of membrane from the transitional endoplasmic reticulum to the Golgi apparatus.


Pssm-ID: 273521 [Multi-domain]  Cd Length: 733  Bit Score: 229.79  E-value: 1.60e-68
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528  97 SLSRDIIRGNPNIKWESIKGLENAKKLLKEAVVMPIKYPTYFNGL-LTPWKGILLFGPPGTGKTMLAKAVATECNTTFFN 175
Cdd:TIGR01243 438 SAIREVLVEVPNVRWSDIGGLEEVKQELREAVEWPLKHPEIFEKMgIRPPKGVLLFGPPGTGKTLLAKAVATESGANFIA 517

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528 176 ISASSVVSKWRGDSEKLIRVLFDLARHHAPSTIFLDEIDAIISQRggeGRSEHEA-SRRLKTELLIQMDGLQKTNELVfV 254
Cdd:TIGR01243 518 VRGPEILSKWVGESEKAIREIFRKARQAAPAIIFFDEIDAIAPAR---GARFDTSvTDRIVNQLLTEMDGIQELSNVV-V 593

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528 255 LAATNLPWELDAAMLR--RLEKRILVPLPDPEARRGMFEMLIPSQPGDEPLPHDVLVEKSEGYSGSDIRILCKEAAMQPL 332
Cdd:TIGR01243 594 IAATNRPDILDPALLRpgRFDRLILVPPPDEEARKEIFKIHTRSMPLAEDVDLEELAEMTEGYTGADIEAVCREAAMAAL 673

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1780599528 333 RRTLAILEDREDVVPEDELPKIGPILPEDIDRALSNTRPSAHLHAHL-YDKFNDDYG 388
Cdd:TIGR01243 674 RESIGSPAKEKLEVGEEEFLKDLKVEMRHFLEALKKVKPSVSKEDMLrYERLAKELK 730
RecA-like_spastin cd19524
ATPase domain of spastin; Spastin is an ATP-dependent microtubule-severing protein involved in ...
 114-278 1.79e-66

ATPase domain of spastin; Spastin is an ATP-dependent microtubule-severing protein involved in microtubule dynamics; it specifically recognizes and cuts microtubules that are polyglutamylated. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410932 [Multi-domain]  Cd Length: 164  Bit Score: 208.17  E-value: 1.79e-66
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528 114 IKGLENAKKLLKEAVVMPIKYPTYFNGLLTPWKGILLFGPPGTGKTMLAKAVATECNTTFFNISASSVVSKWRGDSEKLI 193
Cdd:cd19524     2 IAGQDLAKQALQEMVILPSLRPELFTGLRAPARGLLLFGPPGNGKTMLAKAVAAESNATFFNISAASLTSKYVGEGEKLV 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528 194 RVLFDLARHHAPSTIFLDEIDAIISQRggeGRSEHEASRRLKTELLIQMDGLQKT-NELVFVLAATNLPWELDAAMLRRL 272
Cdd:cd19524    82 RALFAVARELQPSIIFIDEVDSLLSER---SEGEHEASRRLKTEFLIEFDGVQSNgDDRVLVMGATNRPQELDDAVLRRF 158


                  ....*.
gi 1780599528 273 EKRILV 278
Cdd:cd19524   159 TKRVYV 164
cell_div_CdvC NF041006
cell division protein CdvC;
85-372 9.18e-66

cell division protein CdvC;


Pssm-ID: 468935 [Multi-domain]  Cd Length: 371  Bit Score: 213.44  E-value: 9.18e-66
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528  85 PFESAETRTLAESLSRDIIRGNPNIKWESIKGLENAKKLLKEAVVMPIKYPTYFnglltP--W-KGILLFGPPGTGKTML 161
Cdd:NF041006   76 PAEPAGPDVEKESDEELVVKEKPKVTFSDIVGLEDVKEALKEAIVYPSKRPDLF-----PlgWpRGILLYGPPGCGKTML 150

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528 162 AKAVATECNTTFFNISASSVVSKWRGDSEKLIRVLFDLARHHA-----PSTIFLDEIDAII----SQRGGEGrseheasr 232
Cdd:NF041006  151 AAAVANEIDSEFIHVDAASIMSKWLGEAEKNVAKIFKKAREKSkeegkPAIIFIDEIDALLgvysSEVGGEV-------- 222

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528 233 RLKTELLIQMDGLQKTNEL--VFVLAATNLPWELDAAMLRRLEKRILVPLPDPEARRGMFEMLIPSQPGDEPLPHDVLVE 310
Cdd:NF041006  223 RVRNQFLKEMDGLQDKSENyhVYVIGATNKPWRLDEPFLRRFQKRIYIPLPDREQRLELLKYYTSKIKLENDVDLDELAE 302

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1780599528 311 KSEGYSGSDIRILCKEAAMqplrRTLAILEDREDVVPEdelpkigPILPEDIDRALSNTRPS 372
Cdd:NF041006  303 MTEGYTASDIRDIVQAAHM----RVVKEMFEKGLGEPR-------PITMEDFKEVLKIRKPS 353
PRK03992 PRK03992
proteasome-activating nucleotidase; Provisional
 107-349 1.15e-59

proteasome-activating nucleotidase; Provisional


Pssm-ID: 179699 [Multi-domain]  Cd Length: 389  Bit Score: 198.13  E-value: 1.15e-59
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528 107 PNIKWESIKGLENAKKLLKEAVVMPIKYPTYFNGL-LTPWKGILLFGPPGTGKTMLAKAVATECNTTFFNISASSVVSKW 185
Cdd:PRK03992  126 PNVTYEDIGGLEEQIREVREAVELPLKKPELFEEVgIEPPKGVLLYGPPGTGKTLLAKAVAHETNATFIRVVGSELVQKF 205

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528 186 RGDSEKLIRVLFDLARHHAPSTIFLDEIDAIISQRGGEGRS-EHEASRRLkTELLIQMDGLQKTNElVFVLAATNLPWEL 264
Cdd:PRK03992  206 IGEGARLVRELFELAREKAPSIIFIDEIDAIAAKRTDSGTSgDREVQRTL-MQLLAEMDGFDPRGN-VKIIAATNRIDIL 283

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528 265 DAAMLR--RLEKRILVPLPDPEARRGMFEmlIPSQpgDEPLPHDV----LVEKSEGYSGSDIRILCKEAAMqplrrtLAI 338
Cdd:PRK03992  284 DPAILRpgRFDRIIEVPLPDEEGRLEILK--IHTR--KMNLADDVdleeLAELTEGASGADLKAICTEAGM------FAI 353

                         250
                  ....*....|.
gi 1780599528 339 LEDREDVVPED 349
Cdd:PRK03992  354 RDDRTEVTMED 364
RecA-like_ATAD1 cd19520
ATPase domain of ATPase family AAA domain-containing protein 1 and similar ATPase domains; ...
 113-278 1.53e-55

ATPase domain of ATPase family AAA domain-containing protein 1 and similar ATPase domains; ATPase family AAA domain-containing protein 1 (ATAD1, also known as Thorase) is an ATPase that plays a critical role in regulating the surface expression of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors, thereby regulating synaptic plasticity, learning and memory. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410928 [Multi-domain]  Cd Length: 166  Bit Score: 180.31  E-value: 1.53e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528 113 SIKGLENAKKLLKEAVVMPIKYPTYF--NGLLTPWKGILLFGPPGTGKTMLAKAVATECNTTFFNISASSVVSKWRGDSE 190
Cdd:cd19520     1 DIGGLDEVITELKELVILPLQRPELFdnSRLLQPPKGVLLYGPPGCGKTMLAKATAKEAGARFINLQVSSLTDKWYGESQ 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528 191 KLIRVLFDLARHHAPSTIFLDEIDAIISQRggeGRSEHEASRRLKTELLIQMDGLQ-KTNELVFVLAATNLPWELDAAML 269
Cdd:cd19520    81 KLVAAVFSLASKLQPSIIFIDEIDSFLRQR---SSTDHEATAMMKAEFMSLWDGLStDGNCRVIVMGATNRPQDLDEAIL 157


                  ....*....
gi 1780599528 270 RRLEKRILV 278
Cdd:cd19520   158 RRMPKRFHI 166
AAA pfam00004
ATPase family associated with various cellular activities (AAA); AAA family proteins often ...
 148-280 2.58e-55

ATPase family associated with various cellular activities (AAA); AAA family proteins often perform chaperone-like functions that assist in the assembly, operation, or disassembly of protein complexes.


Pssm-ID: 459627 [Multi-domain]  Cd Length: 130  Bit Score: 178.17  E-value: 2.58e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528 148 ILLFGPPGTGKTMLAKAVATECNTTFFNISASSVVSKWRGDSEKLIRVLFDLARHHAPSTIFLDEIDAIISQRggeGRSE 227
Cdd:pfam00004   1 LLLYGPPGTGKTTLAKAVAKELGAPFIEISGSELVSKYVGESEKRLRELFEAAKKLAPCVIFIDEIDALAGSR---GSGG 77

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1780599528 228 HEASRRLKTELLIQMDGLQKTNELVFVLAATNLPWELDAAMLRRLEKRILVPL 280
Cdd:pfam00004  78 DSESRRVVNQLLTELDGFTSSNSKVIVIAATNRPDKLDPALLGRFDRIIEFPL 130
RecA-like_CDC48_r2-like cd19511
second of two ATPase domains of CDC48/p97, PEX1 and -6, VAT and NVL, and similar ATPase ...
 120-278 1.28e-54

second of two ATPase domains of CDC48/p97, PEX1 and -6, VAT and NVL, and similar ATPase domains; This subfamily includes the second of two ATPase domains of the molecular chaperone CDC48 in yeast and p97 or VCP in metazoans, Peroxisomal biogenesis factor 1 (PEX1) and -6 (PEX6), Valosin-containing protein-like ATPase (VAT), and nuclear VCP-like protein (NVL). This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410919 [Multi-domain]  Cd Length: 159  Bit Score: 177.48  E-value: 1.28e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528 120 AKKLLKEAVVMPIKYPTYFNGL-LTPWKGILLFGPPGTGKTMLAKAVATECNTTFFNISASSVVSKWRGDSEKLIRVLFD 198
Cdd:cd19511     1 VKRELKEAVEWPLKHPDAFKRLgIRPPKGVLLYGPPGCGKTLLAKALASEAGLNFISVKGPELFSKYVGESERAVREIFQ 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528 199 LARHHAPSTIFLDEIDAIISQRGGEGRSehEASRRLKTELLIQMDGLQKTNElVFVLAATNLPWELDAAMLR--RLEKRI 276
Cdd:cd19511    81 KARQAAPCIIFFDEIDSLAPRRGQSDSS--GVTDRVVSQLLTELDGIESLKG-VVVIAATNRPDMIDPALLRpgRLDKLI 157


                  ..
gi 1780599528 277 LV 278
Cdd:cd19511   158 YV 159
CDC48 TIGR01243
AAA family ATPase, CDC48 subfamily; This subfamily of the AAA family ATPases includes two ...
 87-373 4.33e-54

AAA family ATPase, CDC48 subfamily; This subfamily of the AAA family ATPases includes two members each from three archaeal species. It also includes yeast CDC48 (cell division control protein 48) and the human ortholog, transitional endoplasmic reticulum ATPase (valosin-containing protein). These proteins in eukaryotes are involved in the budding and transfer of membrane from the transitional endoplasmic reticulum to the Golgi apparatus.


Pssm-ID: 273521 [Multi-domain]  Cd Length: 733  Bit Score: 190.50  E-value: 4.33e-54
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528  87 ESAETRTLAESLSRDIIRGNPNIKWESIKGLENAKKLLKEAVVMPIKYPTYFNGL-LTPWKGILLFGPPGTGKTMLAKAV 165
Cdd:TIGR01243 153 EATEVEIREKPVREEIERKVPKVTYEDIGGLKEAKEKIREMVELPMKHPELFEHLgIEPPKGVLLYGPPGTGKTLLAKAV 232

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528 166 ATECNTTFFNISASSVVSKWRGDSEKLIRVLFDLARHHAPSTIFLDEIDAIISQRggeGRSEHEASRRLKTELLIQMDGL 245
Cdd:TIGR01243 233 ANEAGAYFISINGPEIMSKYYGESEERLREIFKEAEENAPSIIFIDEIDAIAPKR---EEVTGEVEKRVVAQLLTLMDGL 309

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528 246 QKTNElVFVLAATNLPWELDAAMLR--RLEKRILVPLPDPEARRGMFEMLIPSQPGDEPLPHDVLVEKSEGYSGSDIRIL 323
Cdd:TIGR01243 310 KGRGR-VIVIGATNRPDALDPALRRpgRFDREIVIRVPDKRARKEILKVHTRNMPLAEDVDLDKLAEVTHGFVGADLAAL 388

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1780599528 324 CKEAAMQPLRRTLAI----LEDREdvVPEDELPKIgPILPEDIDRALSNTRPSA 373
Cdd:TIGR01243 389 AKEAAMAALRRFIREgkinFEAEE--IPAEVLKEL-KVTMKDFMEALKMVEPSA 439
RecA-like_CDC48_NLV2_r1-like cd19503
first of two ATPase domains of CDC48 and NLV2, and similar ATPase domains; CDC48 in yeast and ...
 113-276 2.71e-51

first of two ATPase domains of CDC48 and NLV2, and similar ATPase domains; CDC48 in yeast and p97 or VCP metazoans is an ATP-dependent molecular chaperone which plays an essential role in many cellular processes, by segregating polyubiquitinated proteins from complexes or membranes. Cdc48/p97 consists of an N-terminal domain and two ATPase domains; this subfamily represents the first of the two ATPase domains. This subfamily also includes the first of the two ATPase domains of NVL (nuclear VCP-like protein) 2, an isoform of NVL mainly present in the nucleolus, which is involved in ribosome biogenesis, in telomerase assembly and the regulation of telomerase activity, and in pre-rRNA processing. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410911 [Multi-domain]  Cd Length: 165  Bit Score: 169.39  E-value: 2.71e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528 113 SIKGLENAKKLLKEAVVMPIKYPTYFNGL-LTPWKGILLFGPPGTGKTMLAKAVATECNTTFFNISASSVVSKWRGDSEK 191
Cdd:cd19503     1 DIGGLDEQIASLKELIELPLKYPELFRALgLKPPRGVLLHGPPGTGKTLLARAVANEAGANFLSISGPSIVSKYLGESEK 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528 192 LIRVLFDLARHHAPSTIFLDEIDAIISQRGGEGRsehEASRRLKTELLIQMDGLQKTNELVfVLAATNLPWELDAAMLR- 270
Cdd:cd19503    81 NLREIFEEARSHAPSIIFIDEIDALAPKREEDQR---EVERRVVAQLLTLMDGMSSRGKVV-VIAATNRPDAIDPALRRp 156


                  ....*..
gi 1780599528 271 -RLEKRI 276
Cdd:cd19503   157 gRFDREV 163
COG1223 COG1223
Predicted ATPase, AAA+ superfamily [General function prediction only];
111-349 5.17e-50

Predicted ATPase, AAA+ superfamily [General function prediction only];


Pssm-ID: 440836 [Multi-domain]  Cd Length: 246  Bit Score: 168.52  E-value: 5.17e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528 111 WESIKGLENAKKLLKEAvvmpIKYPTYFNGL----LTPWKGILLFGPPGTGKTMLAKAVATECNTTFFNISASSVVSKWR 186
Cdd:COG1223     1 LDDVVGQEEAKKKLKLI----IKELRRRENLrkfgLWPPRKILFYGPPGTGKTMLAEALAGELKLPLLTVRLDSLIGSYL 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528 187 GDSEKLIRVLFDLARhHAPSTIFLDEIDAIISQRGGEgrSEHEASRRLKTELLIQMDGLqktNELVFVLAATNLPWELDA 266
Cdd:COG1223    77 GETARNLRKLFDFAR-RAPCVIFFDEFDAIAKDRGDQ--NDVGEVKRVVNALLQELDGL---PSGSVVIAATNHPELLDS 150

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528 267 AMLRRLEKRILVPLPDPEARRGMFEMLIPSQPGDEPLPHDVLVEKSEGYSGSDIRILCKEAamqpLRRtlAILEDREDVV 346
Cdd:COG1223   151 ALWRRFDEVIEFPLPDKEERKEILELNLKKFPLPFELDLKKLAKKLEGLSGADIEKVLKTA----LKK--AILEDREKVT 224


                  ...
gi 1780599528 347 PED 349
Cdd:COG1223   225 KED 227
RecA-like_PAN_like cd19502
proteasome activating nucleotidase PAN and related proteasome subunits; This subfamily ...
 111-276 5.41e-49

proteasome activating nucleotidase PAN and related proteasome subunits; This subfamily contains ATPase subunits of the eukaryotic 26S proteasome, and of the archaeal proteasome which carry out ATP-dependent degradation of substrates of the ubiquitin-proteasome pathway. The eukaryotic 26S proteasome consists of a proteolytic 20S core particle (CP), and a 19S regulatory particle (RP) which provides the ATP-dependence and the specificity for ubiquitinated proteins. In the archaea the RP is a homohexameric complex of proteasome-activating nucleotidase (PAN). This subfamily also includes various eukaryotic 26S subunits including, proteasome 26S subunit, ATPase 2 (PSMC2, also known as S7 and MSS1) which is a member of the 19S RP and has a chaperone like activity; and proteasome 20S subunit alpha 6 (PSMA6, also known as IOTA, p27K, and PROS27) which is a member of the 20S CP. This RecA-like_PAN subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410910 [Multi-domain]  Cd Length: 171  Bit Score: 163.28  E-value: 5.41e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528 111 WESIKGLENAKKLLKEAVVMPIKYPTYFNGL-LTPWKGILLFGPPGTGKTMLAKAVATECNTTFFNISASSVVSKWRGDS 189
Cdd:cd19502     2 YEDIGGLDEQIREIREVVELPLKHPELFEELgIEPPKGVLLYGPPGTGKTLLAKAVANHTDATFIRVVGSELVQKYIGEG 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528 190 EKLIRVLFDLARHHAPSTIFLDEIDAIISQRGGEGRSEHEASRRLKTELLIQMDGLQKTNElVFVLAATNLPWELDAAML 269
Cdd:cd19502    82 ARLVRELFEMAREKAPSIIFIDEIDAIGAKRFDSGTGGDREVQRTMLELLNQLDGFDPRGN-IKVIMATNRPDILDPALL 160


                  ....*....
gi 1780599528 270 R--RLEKRI 276
Cdd:cd19502   161 RpgRFDRKI 169
RecA-like_protease cd19481
proteases similar to RecA; RecA-like NTPases. This family includes the NTP binding domain of ...
 120-278 9.00e-49

proteases similar to RecA; RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410889 [Multi-domain]  Cd Length: 158  Bit Score: 162.45  E-value: 9.00e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528 120 AKKLLKEAVVMPIKYPTYFNGLLTPWKGILLFGPPGTGKTMLAKAVATECNTTFFNISASSVVSKWRGDSEKLIRVLFDL 199
Cdd:cd19481     1 LKASLREAVEAPRRGSRLRRYGLGLPKGILLYGPPGTGKTLLAKALAGELGLPLIVVKLSSLLSKYVGESEKNLRKIFER 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528 200 ARHHAPSTIFLDEIDAIISQRGGEGrsEHEASRRLKTELLIQMDGLQKTNElVFVLAATNLPWELDAAMLR--RLEKRIL 277
Cdd:cd19481    81 ARRLAPCILFIDEIDAIGRKRDSSG--ESGELRRVLNQLLTELDGVNSRSK-VLVIAATNRPDLLDPALLRpgRFDEVIE 157


                  .
gi 1780599528 278 V 278
Cdd:cd19481   158 F 158
RecA-like_CDC48_r2-like cd19528
second of two ATPase domains of CDC48 and similar ATPase domains; CDC48 in yeast and p97 or ...
 121-278 3.42e-48

second of two ATPase domains of CDC48 and similar ATPase domains; CDC48 in yeast and p97 or VCP in metazoans is an ATP-dependent molecular chaperone which plays an essential role in many cellular processes, by segregating polyubiquitinated proteins from complexes or membranes. Cdc48/p97 consists of an N-terminal domain and two ATPase domains; this subfamily represents the second of the two ATPase domains. CDC48's roles include in the fragmentation of Golgi stacks during mitosis and for their reassembly after mitosis, and in the formation of the nuclear envelope, and of the transitional endoplasmic reticulum (tER). This RecA-like_cdc48_r2-like subfamily belongs to the RecA-like family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410936 [Multi-domain]  Cd Length: 161  Bit Score: 161.14  E-value: 3.42e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528 121 KKLLKEAVVMPIKYPTYFNGL-LTPWKGILLFGPPGTGKTMLAKAVATECNTTFFNISASSVVSKWRGDSEKLIRVLFDL 199
Cdd:cd19528     2 KRELQELVQYPVEHPDKFLKFgMTPSKGVLFYGPPGCGKTLLAKAIANECQANFISVKGPELLTMWFGESEANVRDIFDK 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528 200 ARHHAPSTIFLDEIDAIISQRGGEGRSEHEASRRLKTELLIQMDGL-QKTNelVFVLAATNLPWELDAAMLR--RLEKRI 276
Cdd:cd19528    82 ARAAAPCVLFFDELDSIAKARGGNIGDAGGAADRVINQILTEMDGMnTKKN--VFIIGATNRPDIIDPAILRpgRLDQLI 159


                  ..
gi 1780599528 277 LV 278
Cdd:cd19528   160 YI 161
PTZ00454 PTZ00454
26S protease regulatory subunit 6B-like protein; Provisional
 107-349 4.77e-48

26S protease regulatory subunit 6B-like protein; Provisional


Pssm-ID: 240423 [Multi-domain]  Cd Length: 398  Bit Score: 168.02  E-value: 4.77e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528 107 PNIKWESIKGLENAKKLLKEAVVMPIKYPTYFNGL-LTPWKGILLFGPPGTGKTMLAKAVATECNTTFFNISASSVVSKW 185
Cdd:PTZ00454  140 PDVTYSDIGGLDIQKQEIREAVELPLTCPELYEQIgIDPPRGVLLYGPPGTGKTMLAKAVAHHTTATFIRVVGSEFVQKY 219

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528 186 RGDSEKLIRVLFDLARHHAPSTIFLDEIDAIISQRGGEGRSEHEASRRLKTELLIQMDGL-QKTNelVFVLAATNLPWEL 264
Cdd:PTZ00454  220 LGEGPRMVRDVFRLARENAPSIIFIDEVDSIATKRFDAQTGADREVQRILLELLNQMDGFdQTTN--VKVIMATNRADTL 297

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528 265 DAAMLR--RLEKRILVPLPDPEARRGMFEMLIPSQPGDEPLPHDVLVEKSEGYSGSDIRILCKEAAMQPLRRtlaileDR 342
Cdd:PTZ00454  298 DPALLRpgRLDRKIEFPLPDRRQKRLIFQTITSKMNLSEEVDLEDFVSRPEKISAADIAAICQEAGMQAVRK------NR 371


                  ....*..
gi 1780599528 343 EDVVPED 349
Cdd:PTZ00454  372 YVILPKD 378
RecA-like_VCP_r2 cd19529
second of two ATPase domains of Valosin-containing protein-like ATPase (VAT) and similar ...
 120-278 4.58e-47

second of two ATPase domains of Valosin-containing protein-like ATPase (VAT) and similar ATPase domains; The Valosin-containing protein-like ATPase of Thermoplasma acidophilum (VAT), is an archaeal homolog of the ubiquitous Cdc48/p97. It is a protein unfoldase that functions in concert with the 20S proteasome by unfolding proteasome substrates and passing them on for degradation. VAT forms a homohexamer, each monomer contains two tandem ATPase domains, referred to as D1 and D2, and an N-terminal domain. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410937 [Multi-domain]  Cd Length: 159  Bit Score: 158.04  E-value: 4.58e-47
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528 120 AKKLLKEAVVMPIKYPTYFNGL-LTPWKGILLFGPPGTGKTMLAKAVATECNTTFFNISASSVVSKWRGDSEKLIRVLFD 198
Cdd:cd19529     1 VKQELKEAVEWPLLKPEVFKRLgIRPPKGILLYGPPGTGKTLLAKAVATESNANFISVKGPELLSKWVGESEKAIREIFR 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528 199 LARHHAPSTIFLDEIDAIISQRGGEGRSehEASRRLKTELLIQMDGLQKTNELVfVLAATNLPWELDAAMLR--RLEKRI 276
Cdd:cd19529    81 KARQVAPCVIFFDEIDSIAPRRGTTGDS--GVTERVVNQLLTELDGLEEMNGVV-VIAATNRPDIIDPALLRagRFDRLI 157


                  ..
gi 1780599528 277 LV 278
Cdd:cd19529   158 YI 159
RecA-like_FtsH cd19501
ATP-dependent zinc metalloprotease FtsH; FtsH ATPase is a processive, ATP-dependent zinc ...
 109-278 5.64e-44

ATP-dependent zinc metalloprotease FtsH; FtsH ATPase is a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. It is anchored to the cytoplasmic membrane such that the amino- and carboxy-termini are exposed to the cytoplasm. It presents a membrane-bound hexameric structure that is able to unfold and degrade protein substrates. It is comprised of an N-terminal transmembrane region and the larger C-terminal cytoplasmic region, which consists of an ATPase domain and a protease domain. This RecA-Like FTsH subfamily represents the ATPase domain, and belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410909 [Multi-domain]  Cd Length: 171  Bit Score: 150.46  E-value: 5.64e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528 109 IKWESIKGLENAKKLLKEaVVMPIKYPTYFNGL-LTPWKGILLFGPPGTGKTMLAKAVATECNTTFFNISASSVVSKWRG 187
Cdd:cd19501     1 VTFKDVAGCEEAKEELKE-VVEFLKNPEKFTKLgAKIPKGVLLVGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVG 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528 188 DSEKLIRVLFDLARHHAPSTIFLDEIDAIISQRG-GEGRSEHEASRRLkTELLIQMDGLqKTNELVFVLAATNLPWELDA 266
Cdd:cd19501    80 VGASRVRDLFEQAKKNAPCIVFIDEIDAVGRKRGaGLGGGHDEREQTL-NQLLVEMDGF-ESNTGVIVIAATNRPDVLDP 157

                         170
                  ....*....|....
gi 1780599528 267 AMLR--RLEKRILV 278
Cdd:cd19501   158 ALLRpgRFDRQVYV 171
PTZ00361 PTZ00361
26 proteosome regulatory subunit 4-like protein; Provisional
 107-349 5.89e-44

26 proteosome regulatory subunit 4-like protein; Provisional


Pssm-ID: 185575 [Multi-domain]  Cd Length: 438  Bit Score: 158.01  E-value: 5.89e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528 107 PNIKWESIKGLENAKKLLKEAVVMPIKYPTYFNGL-LTPWKGILLFGPPGTGKTMLAKAVATECNTTFFNISASSVVSKW 185
Cdd:PTZ00361  178 PLESYADIGGLEQQIQEIKEAVELPLTHPELYDDIgIKPPKGVILYGPPGTGKTLLAKAVANETSATFLRVVGSELIQKY 257

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528 186 RGDSEKLIRVLFDLARHHAPSTIFLDEIDAIISQRGGEGRSEHEASRRLKTELLIQMDGLQKTNElVFVLAATNLPWELD 265
Cdd:PTZ00361  258 LGDGPKLVRELFRVAEENAPSIVFIDEIDAIGTKRYDATSGGEKEIQRTMLELLNQLDGFDSRGD-VKVIMATNRIESLD 336

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528 266 AAMLR--RLEKRILVPLPDPEARRGMFEMLIPSQPGDEPLPHDVLVEKSEGYSGSDIRILCKEAAMqplrrtLAILEDRE 343
Cdd:PTZ00361  337 PALIRpgRIDRKIEFPNPDEKTKRRIFEIHTSKMTLAEDVDLEEFIMAKDELSGADIKAICTEAGL------LALRERRM 410


                  ....*.
gi 1780599528 344 DVVPED 349
Cdd:PTZ00361  411 KVTQAD 416
RecA-like_NVL_r2-like cd19530
second of two ATPase domains of NVL (nuclear VCP-like protein) and similar ATPase domains; NVL ...
 117-278 1.56e-41

second of two ATPase domains of NVL (nuclear VCP-like protein) and similar ATPase domains; NVL exists in two forms with N-terminal extensions of different lengths in mammalian cells. NVL has two alternatively spliced isoforms, a short form, NVL1, and a long form, NVL2. NVL2, the major species, is mainly present in the nucleolus, whereas NVL1 is nucleoplasmic. Each has an N-terminal domain, followed by two tandem ATPase domains; this subfamily includes the first of the two ATPase domains. NVL2 is involved in the biogenesis of the 60S ribosome subunit by associating specifically with ribosome protein L5 and modulating the function of DOB1. NVL2 is also required for telomerase assembly and the regulation of telomerase activity, and is involved in pre-rRNA processing. The role of NVL1 is unclear. This RecA-like_NVL_r1-like subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410938 [Multi-domain]  Cd Length: 161  Bit Score: 143.78  E-value: 1.56e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528 117 LENAKKLLKEAVVMPIKYPTYFN--GLLTPwKGILLFGPPGTGKTMLAKAVATECNTTFFNISASSVVSKWRGDSEKLIR 194
Cdd:cd19530     1 LDHVREELTMSILRPIKRPDIYKalGIDLP-TGVLLYGPPGCGKTLLAKAVANESGANFISVKGPELLNKYVGESERAVR 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528 195 VLFDLARHHAPSTIFLDEIDAIISQRGGEGrseHEASRRLKTELLIQMDGLQKTNElVFVLAATNLPWELDAAMLR--RL 272
Cdd:cd19530    80 QVFQRARASAPCVIFFDEVDALVPKRGDGG---SWASERVVNQLLTEMDGLEERSN-VFVIAATNRPDIIDPAMLRpgRL 155


                  ....*.
gi 1780599528 273 EKRILV 278
Cdd:cd19530   156 DKTLYV 161
ftsH CHL00176
cell division protein; Validated
 109-337 9.62e-41

cell division protein; Validated


Pssm-ID: 214386 [Multi-domain]  Cd Length: 638  Bit Score: 152.51  E-value: 9.62e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528 109 IKWESIKGLENAKKLLKEaVVMPIKYPTYFNGL-LTPWKGILLFGPPGTGKTMLAKAVATECNTTFFNISASSVVSKWRG 187
Cdd:CHL00176  180 ITFRDIAGIEEAKEEFEE-VVSFLKKPERFTAVgAKIPKGVLLVGPPGTGKTLLAKAIAGEAEVPFFSISGSEFVEMFVG 258

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528 188 DSEKLIRVLFDLARHHAPSTIFLDEIDAIISQRG---GEGRSEHEASRrlkTELLIQMDGLQKTNELVfVLAATNLPWEL 264
Cdd:CHL00176  259 VGAARVRDLFKKAKENSPCIVFIDEIDAVGRQRGagiGGGNDEREQTL---NQLLTEMDGFKGNKGVI-VIAATNRVDIL 334

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1780599528 265 DAAMLR--RLEKRILVPLPDPEARRGMFEMLIPSQPGDEPLPHDVLVEKSEGYSGSDIRILCKEAAMQPLRRTLA 337
Cdd:CHL00176  335 DAALLRpgRFDRQITVSLPDREGRLDILKVHARNKKLSPDVSLELIARRTPGFSGADLANLLNEAAILTARRKKA 409
RecA-like_fidgetin cd19523
ATPase domain of fidgetin; Fidgetin (FIGN) is a ATP-dependent microtubule severing protein. ...
 114-278 1.13e-40

ATPase domain of fidgetin; Fidgetin (FIGN) is a ATP-dependent microtubule severing protein. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410931 [Multi-domain]  Cd Length: 163  Bit Score: 141.56  E-value: 1.13e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528 114 IKGLENAKKLLKEAVVMPIKYPTYFNGLLTPWKGILLFGPPGTGKTMLAKAVATECNTTFFNISASSVVSKWRGDSEKLI 193
Cdd:cd19523     2 IAGLGALKAAIKEEVLWPLLRPDAFSGLLRLPRSILLFGPRGTGKTLLGRCLASQLGATFLRLRGSTLVAKWAGEGEKIL 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528 194 RVLFDLARHHAPSTIFLDEIDAIISQRggegRSEHEASRRLKTELLIQMDG-LQKTNELVFVLAATNLPWELDAAMLRRL 272
Cdd:cd19523    82 QASFLAARCRQPSVLFISDLDALLSSQ----DDEASPVGRLQVELLAQLDGvLGSGEDGVLVVCTTSKPEEIDESLRRYF 157


                  ....*.
gi 1780599528 273 EKRILV 278
Cdd:cd19523   158 SKRLLV 163
RecA-like_CDC48_r1-like cd19519
first of two ATPase domains of CDC48 and similar ATPase domains; CDC48 in yeast and p97 or VCP ...
 114-279 2.30e-39

first of two ATPase domains of CDC48 and similar ATPase domains; CDC48 in yeast and p97 or VCP metazoans is an ATP-dependent molecular chaperone which plays an essential role in many cellular processes, by segregating polyubiquitinated proteins from complexes or membranes. Cdc48/p97 consists of an N-terminal domain and two ATPase domains; this subfamily represents the first of the two ATPase domains. CDC48's roles include in the fragmentation of Golgi stacks during mitosis and for their reassembly after mitosis, and in the formation of the nuclear envelope, and of the transitional endoplasmic reticulum (tER). This RecA-like_cdc48_r1-like subfamily belongs to the RecA-like family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410927 [Multi-domain]  Cd Length: 166  Bit Score: 138.34  E-value: 2.30e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528 114 IKGLENAKKLLKEAVVMPIKYPTYFNGL-LTPWKGILLFGPPGTGKTMLAKAVATECNTTFFNISASSVVSKWRGDSEKL 192
Cdd:cd19519     2 IGGCRKQLAQIREMVELPLRHPELFKAIgIKPPRGILLYGPPGTGKTLIARAVANETGAFFFLINGPEIMSKLAGESESN 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528 193 IRVLFDLARHHAPSTIFLDEIDAIISQRggeGRSEHEASRRLKTELLIQMDGLQKTNElVFVLAATNLPWELDAAMLR-- 270
Cdd:cd19519    82 LRKAFEEAEKNAPAIIFIDEIDAIAPKR---EKTHGEVERRIVSQLLTLMDGLKQRAH-VIVMAATNRPNSIDPALRRfg 157


                  ....*....
gi 1780599528 271 RLEKRILVP 279
Cdd:cd19519   158 RFDREIDIG 166
RecA-like_NVL_r1-like cd19518
first of two ATPase domains of NVL (nuclear VCP-like protein) and similar ATPase domains; NVL ...
 113-276 6.80e-39

first of two ATPase domains of NVL (nuclear VCP-like protein) and similar ATPase domains; NVL exists in two forms with N-terminal extensions of different lengths in mammalian cells. NVL has two alternatively spliced isoforms, a short form, NVL1, and a long form, NVL2. NVL2, the major species, is mainly present in the nucleolus, whereas NVL1 is nucleoplasmic. Each has an N-terminal domain, followed by two tandem ATPase domains; this subfamily includes the first of the two ATPase domains. NVL2 is involved in the biogenesis of the 60S ribosome subunit by associating specifically with ribosome protein L5 and modulating the function of DOB1. NVL2 is also required for telomerase assembly and the regulation of telomerase activity, and is involved in pre-rRNA processing. The role of NVL1 is unclear. This RecA-like_NVL_r1-like subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410926 [Multi-domain]  Cd Length: 169  Bit Score: 137.15  E-value: 6.80e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528 113 SIKGLENAKKLLKEAVVMPIKYPTYFNGL-LTPWKGILLFGPPGTGKTMLAKAVATECNTTFFNISASSVVSKWRGDSEK 191
Cdd:cd19518     1 DIGGMDSTLKELCELLIHPILPPEYFQHLgVEPPRGVLLHGPPGCGKTMLANAIAGELKVPFLKISATEIVSGVSGESEE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528 192 LIRVLFDLARHHAPSTIFLDEIDAIISQRGGEGRsehEASRRLKTELLIQMDGL---QKTNELVFVLAATNLPWELDAAM 268
Cdd:cd19518    81 KIRELFDQAISNAPCIVFIDEIDAITPKRESAQR---EMERRIVSQLLTCMDELnneKTAGGPVLVIGATNRPDSLDPAL 157

                         170
                  ....*....|
gi 1780599528 269 LR--RLEKRI 276
Cdd:cd19518   158 RRagRFDREI 167
hflB PRK10733
ATP-dependent zinc metalloprotease FtsH;
92-340 6.80e-38

ATP-dependent zinc metalloprotease FtsH;


Pssm-ID: 182683 [Multi-domain]  Cd Length: 644  Bit Score: 144.41  E-value: 6.80e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528  92 RTLAESLSRDIIRgnpnIKWESIKGLENAKKLLKEaVVMPIKYPTYFNGL--LTPwKGILLFGPPGTGKTMLAKAVATEC 169
Cdd:PRK10733  136 KSKARMLTEDQIK----TTFADVAGCDEAKEEVAE-LVEYLREPSRFQKLggKIP-KGVLMVGPPGTGKTLLAKAIAGEA 209

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528 170 NTTFFNISASSVVSKWRGDSEKLIRVLFDLARHHAPSTIFLDEIDAIISQRGGEGRSEHEASRRLKTELLIQMDGLQKtN 249
Cdd:PRK10733  210 KVPFFTISGSDFVEMFVGVGASRVRDMFEQAKKAAPCIIFIDEIDAVGRQRGAGLGGGHDEREQTLNQMLVEMDGFEG-N 288

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528 250 ELVFVLAATNLPWELDAAMLR--RLEKRILVPLPDPEARRGMFEMLIPSQPGDEPLPHDVLVEKSEGYSGSDIRILCKEA 327
Cdd:PRK10733  289 EGIIVIAATNRPDVLDPALLRpgRFDRQVVVGLPDVRGREQILKVHMRRVPLAPDIDAAIIARGTPGFSGADLANLVNEA 368

                         250
                  ....*....|....*.
gi 1780599528 328 AMQPLR---RTLAILE 340
Cdd:PRK10733  369 ALFAARgnkRVVSMVE 384
RecA-like_PEX6_r2 cd19527
second of two ATPase domains of Peroxisomal biogenesis factor 6 (PEX6); PEX6(also known as ...
 121-278 9.18e-37

second of two ATPase domains of Peroxisomal biogenesis factor 6 (PEX6); PEX6(also known as Peroxin61)/PEX1 is a protein unfoldase; PEX6 and PEX1 form a heterohexameric Type-2 AAA-ATPase complex and are essential for peroxisome biogenesis as they are required for the import of folded proteins into the peroxisomal matrix. This subfamily represents the second ATPase domain of PEX6. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410935 [Multi-domain]  Cd Length: 160  Bit Score: 131.10  E-value: 9.18e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528 121 KKLLKEAVVMPIKYPTYFNGLLTPWKGILLFGPPGTGKTMLAKAVATECNTTFFNISASSVVSKWRGDSEKLIRVLFDLA 200
Cdd:cd19527     2 KKEILDTIQLPLEHPELFSSGLRKRSGILLYGPPGTGKTLLAKAIATECSLNFLSVKGPELINMYIGESEANVREVFQKA 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528 201 RHHAPSTIFLDEIDAIISQRGGEGRSeHEASRRLKTELLIQMDGLQKTNELVFVLAATNLPWELDAAMLR--RLEKRILV 278
Cdd:cd19527    82 RDAKPCVIFFDELDSLAPSRGNSGDS-GGVMDRVVSQLLAELDGMSSSGQDVFVIGATNRPDLLDPALLRpgRFDKLLYL 160
RecA-like_Yta7-like cd19517
ATPase domain of Saccharomyces cerevisiae Yta7 and similar ATPase domains; Saccharomyces ...
 113-271 1.63e-34

ATPase domain of Saccharomyces cerevisiae Yta7 and similar ATPase domains; Saccharomyces cerevisiae Yta7 is a chromatin-associated AAA-ATPase involved in regulation of chromatin dynamics. Its human ortholog ANCCA/ATAD2 transcriptionally activates pathways of malignancy in a broad range of cancers. The RecA-like_Yta7 subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410925 [Multi-domain]  Cd Length: 170  Bit Score: 125.70  E-value: 1.63e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528 113 SIKGLENAKKLLKEAVVMPIKYPTYFNGL-LTPWKGILLFGPPGTGKTMLAKAVATECNT-----TFFNISASSVVSKWR 186
Cdd:cd19517     1 DIGGLSHYINQLKEMVFFPLLYPEVFAKFkITPPRGVLFHGPPGTGKTLMARALAAECSKggqkvSFFMRKGADCLSKWV 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528 187 GDSEKLIRVLFDLARHHAPSTIFLDEIDAIISQRGGEGRSEHEAsrrLKTELLIQMDGLQKTNELVfVLAATNLPWELDA 266
Cdd:cd19517    81 GEAERQLRLLFEEAYRMQPSIIFFDEIDGLAPVRSSKQEQIHAS---IVSTLLALMDGLDNRGQVV-VIGATNRPDALDP 156


                  ....*
gi 1780599528 267 AmLRR 271
Cdd:cd19517   157 A-LRR 160
HflB COG0465
ATP-dependent Zn proteases [Posttranslational modification, protein turnover, chaperones];
116-328 1.91e-34

ATP-dependent Zn proteases [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440233 [Multi-domain]  Cd Length: 583  Bit Score: 134.01  E-value: 1.91e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528 116 GLENAKKLLKEaVVMPIKYPTYFNGL--LTPwKGILLFGPPGTGKTMLAKAVATECNTTFFNISASSVVskwrgdsEKLI 193
Cdd:COG0465   146 GVDEAKEELQE-IVDFLKDPEKFTRLgaKIP-KGVLLVGPPGTGKTLLAKAVAGEAGVPFFSISGSDFV-------EMFV 216

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528 194 -----RV--LFDLARHHAPSTIFLDEIDAIISQRG---GEGRSEHEasrrlKT--ELLIQMDGLQkTNELVFVLAATNLP 261
Cdd:COG0465   217 gvgasRVrdLFEQAKKNAPCIIFIDEIDAVGRQRGaglGGGHDERE-----QTlnQLLVEMDGFE-GNEGVIVIAATNRP 290

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1780599528 262 WELDAAMLR--RLEKRILVPLPDPEARRGMFEmlIPSQpgDEPLPHDVLVEK----SEGYSGSDIRILCKEAA 328
Cdd:COG0465   291 DVLDPALLRpgRFDRQVVVDLPDVKGREAILK--VHAR--KKPLAPDVDLEViarrTPGFSGADLANLVNEAA 359
RecA-like_PEX1_r2 cd19526
second of two ATPase domains of Peroxisomal biogenesis factor 1 (PEX1); PEX1(also known as ...
 120-277 1.49e-33

second of two ATPase domains of Peroxisomal biogenesis factor 1 (PEX1); PEX1(also known as Peroxin-1)/PEX6 is a protein unfoldase; PEX1 and PEX6 form a heterohexameric Type-2 AAA-ATPase complex and are essential for peroxisome biogenesis as they are required for the import of folded proteins into the peroxisomal matrix. PEX-1 is required for stability of PEX5. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410934 [Multi-domain]  Cd Length: 158  Bit Score: 122.54  E-value: 1.49e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528 120 AKKLLKEAVVMPIKYPTYFNGL-LTPWKGILLFGPPGTGKTMLAKAVATECNTTFFNISASSVVSKWRGDSEKLIRVLFD 198
Cdd:cd19526     1 VKKALEETIEWPSKYPKIFASSpLRLRSGILLYGPPGCGKTLLASAIASECGLNFISVKGPELLNKYIGASEQNVRDLFS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528 199 LARHHAPSTIFLDEIDAIISQRGgegrseHEAS---RRLKTELLIQMDGLQKTNElVFVLAATNLPWELDAAMLR--RLE 273
Cdd:cd19526    81 RAQSAKPCILFFDEFDSIAPKRG------HDSTgvtDRVVNQLLTQLDGVEGLDG-VYVLAATSRPDLIDPALLRpgRLD 153


                  ....
gi 1780599528 274 KRIL 277
Cdd:cd19526   154 KLVY 157
AAA cd00009
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ...
 115-280 6.17e-24

The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.


Pssm-ID: 99707 [Multi-domain]  Cd Length: 151  Bit Score: 96.45  E-value: 6.17e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528 115 KGLENAKKLLKEAVvmpikyptyfngLLTPWKGILLFGPPGTGKTMLAKAVATEC---NTTFFNISASSVVSKWRGDSEK 191
Cdd:cd00009     1 VGQEEAIEALREAL------------ELPPPKNLLLYGPPGTGKTTLARAIANELfrpGAPFLYLNASDLLEGLVVAELF 68

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528 192 ---LIRVLFDLARHHAPSTIFLDEIDAIisqrggegrseheaSRRLKTELLIQMDGL---QKTNELVFVLAATNLPWELD 265
Cdd:cd00009    69 ghfLVRLLFELAEKAKPGVLFIDEIDSL--------------SRGAQNALLRVLETLndlRIDRENVRVIGATNRPLLGD 134

                         170
                  ....*....|....*..
gi 1780599528 266 AAM--LRRLEKRILVPL 280
Cdd:cd00009   135 LDRalYDRLDIRIVIPL 151
RecA-like_NSF-SEC18_r1-like cd19504
first of two ATPase domains of NSF and SEC18, and similar ATPase domains; ...
 146-273 1.65e-18

first of two ATPase domains of NSF and SEC18, and similar ATPase domains; N-ethylmaleimide-sensitive factor (NSF) and Saccharomyces cerevisiae Vesicular-fusion protein Sec18, key factors for eukaryotic trafficking, are ATPases and SNARE disassembly chaperones. NSF/Sec18 activate or prime SNAREs, the terminal catalysts of membrane fusion. Sec18/NSF associates with SNARE complexes through binding Sec17/alpha-SNAP. Sec18 has an N-terminal cap domain and two nucleotide-binding domains (D1 and D2) which form the two rings of the hexameric complex. The hydrolysis of ATP by D1 generates most of the energy necessary to disassemble inactive SNARE bundles, while the D2 ring binds ATP to stabilize the homohexamer. This subfamily includes the first (D1) ATPase domain of NSF/Sec18, and belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410912 [Multi-domain]  Cd Length: 177  Bit Score: 82.54  E-value: 1.65e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528 146 KGILLFGPPGTGKTMLAKAVATECNTTFFNI-SASSVVSKWRGDSEKLIRVLF--------DLARHHAPSTIFLDEIDAI 216
Cdd:cd19504    36 KGILLYGPPGTGKTLMARQIGKMLNAREPKIvNGPEILNKYVGESEANIRKLFadaeeeqrRLGANSGLHIIIFDEIDAI 115

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1780599528 217 ISQRG--GEGRSEHEAsrrLKTELLIQMDGLQKTNElVFVLAATNLPWELDAAMLR--RLE 273
Cdd:cd19504   116 CKQRGsmAGSTGVHDT---VVNQLLSKIDGVEQLNN-ILVIGMTNRKDLIDEALLRpgRLE 172
RecA-like_Ycf46-like cd19507
ATPase domain of Ycf46 and similar ATPase domains; Ycf46 may play a role in the regulation of ...
 114-264 4.02e-18

ATPase domain of Ycf46 and similar ATPase domains; Ycf46 may play a role in the regulation of photosynthesis in cyanobacteria, especially in CO2 uptake and utilization. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410915 [Multi-domain]  Cd Length: 161  Bit Score: 80.88  E-value: 4.02e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528 114 IKGLENAKK-LLKEAVVMPIKYPTYfnGLLTPwKGILLFGPPGTGKTMLAKAVATECNTTFFNISASSVVSKWRGDSEKL 192
Cdd:cd19507     2 VGGLDNLKDwLKKRKAAFSKQASAY--GLPTP-KGLLLVGIQGTGKSLTAKAIAGVWQLPLLRLDMGRLFGGLVGESESR 78

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1780599528 193 IRVLFDLARHHAPSTIFLDEIDAIISQRGGEGrsEHEASRRLKTELLIQMDglQKTNElVFVLAATN----LPWEL 264
Cdd:cd19507    79 LRQMIQTAEAIAPCVLWIDEIEKGFSNADSKG--DSGTSSRVLGTFLTWLQ--EKKKP-VFVVATANnvqsLPPEL 149
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
 144-282 2.19e-16

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 75.49  E-value: 2.19e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528  144 PWKGILLFGPPGTGKTMLAKAVATECNTT---FFNISAS--------------SVVSKWRGDSEKLIRVLFDLARHHAPS 206
Cdd:smart00382   1 PGEVILIVGPPGSGKTTLARALARELGPPgggVIYIDGEdileevldqllliiVGGKKASGSGELRLRLALALARKLKPD 80

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1780599528  207 TIFLDEIDAIIsqrggegRSEHEASRRLKTELLIQMDGLQKTNELVfVLAATNLPWELDAAMLRRLEKRILVPLPD 282
Cdd:smart00382  81 VLILDEITSLL-------DAEQEALLLLLEELRLLLLLKSEKNLTV-ILTTNDEKDLGPALLRRRFDRRIVLLLIL 148
RecA-like_Pch2-like cd19508
ATPase domain of Pachytene checkpoint 2 (Pch2) and similar ATPase domains; Pch2 (known as ...
 148-271 8.62e-13

ATPase domain of Pachytene checkpoint 2 (Pch2) and similar ATPase domains; Pch2 (known as Thyroid hormone receptor interactor 13 (TRIP13) and 16E1BP) is a key regulator of specific chromosomal events, like the control of G2/prophase processes such as DNA break formation and recombination, checkpoint signaling, and chromosome synapsis. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion


Pssm-ID: 410916 [Multi-domain]  Cd Length: 199  Bit Score: 66.70  E-value: 8.62e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528 148 ILLFGPPGTGKTMLAKAVATE----CNTT-----FFNISASSVVSKWRGDSEKLIRVLFD-----LARHHAPSTIFLDEI 213
Cdd:cd19508    55 VLLHGPPGTGKTSLCKALAQKlsirLSSRyrygqLIEINSHSLFSKWFSESGKLVTKMFQkiqelIDDKDALVFVLIDEV 134

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1780599528 214 DAIISQRGG-EGRSEHEASRRLKTELLIQMDGLqKTNELVFVLAATNLPWELDAAMLRR 271
Cdd:cd19508   135 ESLAAARSAsSSGTEPSDAIRVVNAVLTQIDRI-KRYHNNVILLTSNLLEKIDVAFVDR 192
ycf46 CHL00195
Ycf46; Provisional
 106-375 1.69e-12

Ycf46; Provisional


Pssm-ID: 177094 [Multi-domain]  Cd Length: 489  Bit Score: 68.51  E-value: 1.69e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528 106 NPNIKWESIKGLENAKKLL-KEAVVMPIKYPTYfnGLLTPwKGILLFGPPGTGKTMLAKAVATECNTTFFNISASSVVSK 184
Cdd:CHL00195  222 SVNEKISDIGGLDNLKDWLkKRSTSFSKQASNY--GLPTP-RGLLLVGIQGTGKSLTAKAIANDWQLPLLRLDVGKLFGG 298

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528 185 WRGDSEKLIRVLFDLARHHAPSTIFLDEIDAIISQ---RGGEGRSeheaSRRLKTelLIQMdgLQKTNELVFVLAATN-- 259
Cdd:CHL00195  299 IVGESESRMRQMIRIAEALSPCILWIDEIDKAFSNsesKGDSGTT----NRVLAT--FITW--LSEKKSPVFVVATANni 370

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528 260 --LPWEldaaMLR--RLEKRILVPLPDPEARRGMFEMLIP-SQPGD-EPLPHDVLVEKSEGYSGSDIRILCKEaAMQplr 333
Cdd:CHL00195  371 dlLPLE----ILRkgRFDEIFFLDLPSLEEREKIFKIHLQkFRPKSwKKYDIKKLSKLSNKFSGAEIEQSIIE-AMY--- 442

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|..
gi 1780599528 334 rtLAILEDREdvvpedelpkigpILPEDIDRALSNTRPSAHL 375
Cdd:CHL00195  443 --IAFYEKRE-------------FTTDDILLALKQFIPLAQT 469
RecA-like_IQCA1 cd19506
ATPase domain of IQ and AAA domain-containing protein 1 (IQCA1); IQCA1 (also known as dynein ...
 146-277 3.41e-12

ATPase domain of IQ and AAA domain-containing protein 1 (IQCA1); IQCA1 (also known as dynein regulatory complex subunit 11, DRC11 and IQCA) is an ATPase subunit of the nexin-dynein regulatory complex (N-DRC). The 9 + 2 axoneme of most motile cilia and flagella consists of nine outer doublet microtubules arranged in a ring surrounding a central pair of two singlet microtubules. The N-DRC complex maintains alignment between outer doublet microtubules and limits microtubule sliding in motile axonemes. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410914 [Multi-domain]  Cd Length: 160  Bit Score: 64.09  E-value: 3.41e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528 146 KGILLFGPPGTGKTMLAKAVATECNTTFFNISASSVVSKWRGDS--EKLIRVLFDLARHHAPSTIFLDEIDAIISQRGGE 223
Cdd:cd19506    27 KSLLLAGPSGVGKKMLVHAICTETGANLFNLSPSNIAGKYPGKNglQMMLHLVLKVARQLQPSVIWIGDAEKTFYKKVPK 106

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1780599528 224 GRSEHEaSRRLKTELLIQMDGLQKTNELVFVlAATNLPWELDAAMLRRLEKRIL 277
Cdd:cd19506   107 TEKQLD-PKRLKKDLPKILKSLKPEDRVLIV-GTTSRPFEADLKSFCKVYNKII 158
RecA-like_BCS1 cd19510
Mitochondrial chaperone BCS1; Mitochondrial chaperone BCS1 is necessary for the assembly of ...
 132-271 7.08e-12

Mitochondrial chaperone BCS1; Mitochondrial chaperone BCS1 is necessary for the assembly of mitochondrial respiratory chain complex III and plays an important role in the maintenance of mitochondrial tubular networks, respiratory chain assembly and formation of the LETM1 complex. RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410918 [Multi-domain]  Cd Length: 153  Bit Score: 62.75  E-value: 7.08e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528 132 IKYPTYFNGLLTPWK-GILLFGPPGTGKTMLAKAVATECNTTFFNISASSVVskwrgDSEKLIRVLfdLARHHAPSTIFL 210
Cdd:cd19510     9 IKNEDWYNDRGIPYRrGYLLYGPPGTGKSSFIAALAGELDYDICDLNLSEVV-----LTDDRLNHL--LNTAPKQSIILL 81

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1780599528 211 DEIDAIISQR--GGEGRSEHEASRRLK-TELLIQMDGLQKTNELVFVLaATNLPWELDAAMLRR 271
Cdd:cd19510    82 EDIDAAFESRehNKKNPSAYGGLSRVTfSGLLNALDGVASSEERIVFM-TTNHIERLDPALIRP 144
RecA-like_ATAD3-like cd19512
ATPase domains of ATPase AAA-domain protein 3A (ATAD3A), -3B, and -3C, and similar ATPase ...
 144-276 1.95e-11

ATPase domains of ATPase AAA-domain protein 3A (ATAD3A), -3B, and -3C, and similar ATPase domains; ATPase AAA-domain protein 3 (ATAD3) is a ubiquitously expressed mitochondrial protein involved in mitochondrial dynamics, DNA-nucleoid structural organization, cholesterol transport and steroidogenesis. The ATAD3 gene family in human comprises three paralog genes: ATAD3A, ATAD3B and ATAD3C. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410920 [Multi-domain]  Cd Length: 150  Bit Score: 61.77  E-value: 1.95e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528 144 PWKGILLFGPPGTGKTMLAKAVATECNTTFFNISASSVVSKWRgDSEKLIRVLFDLARHHAPSTI-FLDEIDAIISQRGG 222
Cdd:cd19512    21 LYRNILFYGPPGTGKTLFAKKLALHSGMDYAIMTGGDVAPMGR-EGVTAIHKVFDWANTSRRGLLlFVDEADAFLRKRST 99

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1780599528 223 EGRSehEASRRLKTELLIQMDglQKTNELVFVLaATNLPWELDAAMLRRLEKRI 276
Cdd:cd19512   100 EKIS--EDLRAALNAFLYRTG--EQSNKFMLVL-ASNQPEQFDWAINDRIDEMV 148
RarA COG2256
Replication-associated recombination protein RarA (DNA-dependent ATPase) [Replication, ...
 148-213 1.65e-08

Replication-associated recombination protein RarA (DNA-dependent ATPase) [Replication, recombination and repair];


Pssm-ID: 441857 [Multi-domain]  Cd Length: 439  Bit Score: 56.22  E-value: 1.65e-08
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1780599528 148 ILLFGPPGTGKTMLAKAVATECNTTFFNISA--SSVvskwrgdseKLIRVLFDLARHHAPS---TI-FLDEI 213
Cdd:COG2256    52 MILWGPPGTGKTTLARLIANATDAEFVALSAvtSGV---------KDIREVIEEARERRAYgrrTIlFVDEI 114
AAA_lid_3 pfam17862
AAA+ lid domain; This entry represents the alpha helical AAA+ lid domain that is found to the ...
 306-343 2.00e-08

AAA+ lid domain; This entry represents the alpha helical AAA+ lid domain that is found to the C-terminus of AAA domains.


Pssm-ID: 465537 [Multi-domain]  Cd Length: 45  Bit Score: 49.84  E-value: 2.00e-08
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 1780599528 306 DVLVEKSEGYSGSDIRILCKEAAMQPLRRTLAILEDRE 343
Cdd:pfam17862   5 EELAERTEGFSGADLEALCREAALAALRRGLEAVTQED 42
PRK13342 PRK13342
recombination factor protein RarA; Reviewed
 148-213 5.05e-08

recombination factor protein RarA; Reviewed


Pssm-ID: 237355 [Multi-domain]  Cd Length: 413  Bit Score: 54.32  E-value: 5.05e-08
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528 148 ILLFGPPGTGKTMLAKAVATECNTTFFNISASSvvskwrgDSEKLIRVLFDLARHHAPS---TI-FLDEI 213
Cdd:PRK13342   39 MILWGPPGTGKTTLARIIAGATDAPFEALSAVT-------SGVKDLREVIEEARQRRSAgrrTIlFIDEI 101
TIP49 COG1224
DNA helicase TIP49, TBP-interacting protein [Transcription];
146-196 1.14e-06

DNA helicase TIP49, TBP-interacting protein [Transcription];


Pssm-ID: 440837 [Multi-domain]  Cd Length: 452  Bit Score: 50.35  E-value: 1.14e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1780599528 146 KGILLFGPPGTGKTMLAKAVATEC--NTTFFNISASSVVSKWRGDSEKLIRVL 196
Cdd:COG1224    65 KGILIVGPPGTGKTALAVAIARELgeDTPFVAISGSEIYSAELKKTEFLMQAL 117
AAA_2 pfam07724
AAA domain (Cdc48 subfamily); This Pfam entry includes some of the AAA proteins not detected ...
 148-216 1.31e-05

AAA domain (Cdc48 subfamily); This Pfam entry includes some of the AAA proteins not detected by the pfam00004 model.


Pssm-ID: 400187 [Multi-domain]  Cd Length: 168  Bit Score: 45.26  E-value: 1.31e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528 148 ILLFGPPGTGKTMLAKAVA-----TECNTTFFNISA---SSVVSKWRGDSEKLIRV-----LFDLARHHAPSTIFLDEID 214
Cdd:pfam07724   6 FLFLGPTGVGKTELAKALAellfgDERALIRIDMSEymeEHSVSRLIGAPPGYVGYeeggqLTEAVRRKPYSIVLIDEIE 85


                  ..
gi 1780599528 215 AI 216
Cdd:pfam07724  86 KA 87
RecA-like_HslU cd19498
ATP-dependent protease ATPase subunit HslU; HslU is a component of the ATP-dependent protease ...
 142-232 2.19e-05

ATP-dependent protease ATPase subunit HslU; HslU is a component of the ATP-dependent protease HslVU. In HslVU, HslU ATPase serves to unfold and translocate protein substrate, and the HslV protease degrades the unfolded proteins. This RecA-like_HslU subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410906 [Multi-domain]  Cd Length: 183  Bit Score: 44.68  E-value: 2.19e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528 142 LTPwKGILLFGPPGTGKTMLAKAVATECNTTFFNISAS--SVVSKWRGDSEKLIRVLFDlarhhapSTIFLDEIDAIISQ 219
Cdd:cd19498    44 VTP-KNILMIGPTGVGKTEIARRLAKLAGAPFIKVEATkfTEVGYVGRDVESIIRDLVE-------GIVFIDEIDKIAKR 115

                          90
                  ....*....|...
gi 1780599528 220 RGGEGrseHEASR 232
Cdd:cd19498   116 GGSSG---PDVSR 125
RecA-like_Ycf2 cd19505
ATPase domain of plant YCF2; Ycf2 is a chloroplast ATPase which has an essential function; ...
 142-276 3.32e-05

ATPase domain of plant YCF2; Ycf2 is a chloroplast ATPase which has an essential function; however, its function remains unclear. The gene encoding YCF2 is the largest known plastid gene in angiosperms and has been used to predict phylogenetic relationships. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410913 [Multi-domain]  Cd Length: 161  Bit Score: 43.90  E-value: 3.32e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528 142 LTPWKGILLFGPPGTGKTMLAKAVATECNTTFFNISASSVVSKW--------------RGDSEKLIRVLFDLARHHAPST 207
Cdd:cd19505     9 LSPSKGILLIGSIETGRSYLIKSLAANSYVPLIRISLNKLLYNKpdfgnddwidgmliLKESLHRLNLQFELAKAMSPCI 88

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1780599528 208 IFLDEIDAIISQRGGEgrsEHEASRRLKTELL---IQMDGLQKTNELVFVLAATNLPWELDAAML--RRLEKRI 276
Cdd:cd19505    89 IWIPNIHELNVNRSTQ---NLEEDPKLLLGLLlnyLSRDFEKSSTRNILVIASTHIPQKVDPALIapNRLDTCI 159
ruvB PRK00080
Holliday junction branch migration DNA helicase RuvB;
148-213 7.98e-05

Holliday junction branch migration DNA helicase RuvB;


Pssm-ID: 234619 [Multi-domain]  Cd Length: 328  Bit Score: 44.35  E-value: 7.98e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1780599528 148 ILLFGPPGTGKTMLAKAVATECNTTFFNISAsSVVSKwRGDsekLIRVLFDLARHhapSTIFLDEI 213
Cdd:PRK00080   54 VLLYGPPGLGKTTLANIIANEMGVNIRITSG-PALEK-PGD---LAAILTNLEEG---DVLFIDEI 111
TIP49 pfam06068
TIP49 P-loop domain; This family consists of the C-terminal region of several eukaryotic and ...
 146-183 1.47e-04

TIP49 P-loop domain; This family consists of the C-terminal region of several eukaryotic and archaeal RuvB-like 1 (Pontin or TIP49a) and RuvB-like 2 (Reptin or TIP49b) proteins. The N-terminal domain contains the pfam00004 domain. In zebrafish, the liebeskummer (lik) mutation, causes development of hyperplastic embryonic hearts. lik encodes Reptin, a component of a DNA-stimulated ATPase complex. Beta-catenin and Pontin, a DNA-stimulated ATPase that is often part of complexes with Reptin, are in the same genetic pathways. The Reptin/Pontin ratio serves to regulate heart growth during development, at least in part via the beta-catenin pathway. TBP-interacting protein 49 (TIP49) was originally identified as a TBP-binding protein, and two related proteins are encoded by individual genes, tip49a and b. Although the function of this gene family has not been elucidated, they are supposed to play a critical role in nuclear events because they interact with various kinds of nuclear factors and have DNA helicase activities.TIP49a has been suggested to act as an autoantigen in some patients with autoimmune diseases.


Pssm-ID: 399217 [Multi-domain]  Cd Length: 347  Bit Score: 43.45  E-value: 1.47e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 1780599528 146 KGILLFGPPGTGKTMLAKAVATECN--TTFFNISASSVVS 183
Cdd:pfam06068  51 RAVLIAGPPGTGKTALAIAISKELGedTPFTSISGSEVYS 90
RecA-like_Lon cd19500
lon protease homolog 2 peroxisomal; Lon protease (also known as Lon peptidase) is an ...
 148-177 2.60e-04

lon protease homolog 2 peroxisomal; Lon protease (also known as Lon peptidase) is an evolutionarily conserved ATP-dependent serine protease, present in bacteria and eukaryotic mitochondria and peroxisomes, which mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Lon protease is both an ATP-dependent peptidase and a protein-activated ATPase. This RecA-like Lon domain subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410908 [Multi-domain]  Cd Length: 182  Bit Score: 41.39  E-value: 2.60e-04
                          10        20        30
                  ....*....|....*....|....*....|.
gi 1780599528 148 ILLF-GPPGTGKTMLAKAVATECNTTFFNIS 177
Cdd:cd19500    39 ILCLvGPPGVGKTSLGKSIARALGRKFVRIS 69
YifB COG0606
Predicted Mg-chelatase, contains ChlI-like and ATPase domains, YifB family [Posttranslational ...
 148-167 2.71e-04

Predicted Mg-chelatase, contains ChlI-like and ATPase domains, YifB family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440371 [Multi-domain]  Cd Length: 502  Bit Score: 42.72  E-value: 2.71e-04
                          10        20
                  ....*....|....*....|
gi 1780599528 148 ILLFGPPGTGKTMLAKAVAT 167
Cdd:COG0606   214 LLMIGPPGSGKTMLARRLPG 233
PRK08116 PRK08116
hypothetical protein; Validated
 147-250 3.76e-04

hypothetical protein; Validated


Pssm-ID: 236153 [Multi-domain]  Cd Length: 268  Bit Score: 41.93  E-value: 3.76e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528 147 GILLFGPPGTGKTMLAKAVATECnttffnisassvvskwrgdSEKLIRVLFDlarhhapSTI-FLDEIDAIISQRGGEGR 225
Cdd:PRK08116  116 GLLLWGSVGTGKTYLAACIANEL-------------------IEKGVPVIFV-------NFPqLLNRIKSTYKSSGKEDE 169

                          90       100
                  ....*....|....*....|....*..
gi 1780599528 226 SEHeaSRRLK-TELLIQMD-GLQKTNE 250
Cdd:PRK08116  170 NEI--IRSLVnADLLILDDlGAERDTE 194
T7SS_EccA TIGR03922
type VII secretion AAA-ATPase EccA; This model represents the AAA family ATPase, EccA, of the ...
 116-224 5.23e-04

type VII secretion AAA-ATPase EccA; This model represents the AAA family ATPase, EccA, of the actinobacterial flavor of type VII secretion systems. Species such as Mycobacterium tuberculosis have several instances of this system per genome, designated EccA1, EccA2, etc. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 188437 [Multi-domain]  Cd Length: 557  Bit Score: 42.14  E-value: 5.23e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528 116 GLENAK---KLLKEAVVMPIKYPTYfnGLLTPW--KGILLFGPPGTGKTMLAKAVATE-CNTTFF------NISASSVVS 183
Cdd:TIGR03922 280 GLERVKrqvAALKSSTAMALARAER--GLPVAQtsNHMLFAGPPGTGKTTIARVVAKIyCGLGVLrkplvrEVSRADLIG 357

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 1780599528 184 KWRGDSEKLIRVLFDLARHHApstIFLDEIDAIISQRGGEG 224
Cdd:TIGR03922 358 QYIGESEAKTNEIIDSALGGV---LFLDEAYTLVETGYGQK 395
DnaC COG1484
DNA replication protein DnaC [Replication, recombination and repair];
146-240 7.09e-04

DNA replication protein DnaC [Replication, recombination and repair];


Pssm-ID: 441093 [Multi-domain]  Cd Length: 242  Bit Score: 40.92  E-value: 7.09e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528 146 KGILLFGPPGTGKTMLAKAVATECnttffnisassvvskwrgdSEKLIRVLFdlarHHAPStiFLDEI-DAIisqrgGEG 224
Cdd:COG1484   100 ENLILLGPPGTGKTHLAIALGHEA-------------------CRAGYRVRF----TTAPD--LVNELkEAR-----ADG 149

                          90
                  ....*....|....*.
gi 1780599528 225 RSEHEASRRLKTELLI 240
Cdd:COG1484   150 RLERLLKRLAKVDLLI 165
Mg_chelatase pfam01078
Magnesium chelatase, subunit ChlI; Magnesium-chelatase is a three-component enzyme that ...
 148-167 7.12e-04

Magnesium chelatase, subunit ChlI; Magnesium-chelatase is a three-component enzyme that catalyzes the insertion of Mg2+ into protoporphyrin IX. This is the first unique step in the synthesis of (bacterio)chlorophyll. Due to this, it is thought that Mg-chelatase has an important role in channelling inter- mediates into the (bacterio)chlorophyll branch in response to conditions suitable for photosynthetic growth. ChlI and BchD have molecular weight between 38-42 kDa.


Pssm-ID: 426032 [Multi-domain]  Cd Length: 207  Bit Score: 40.60  E-value: 7.12e-04
                          10        20
                  ....*....|....*....|
gi 1780599528 148 ILLFGPPGTGKTMLAKAVAT 167
Cdd:pfam01078  25 LLMIGPPGSGKTMLAKRLPG 44
MoxR COG0714
MoxR-like ATPase [General function prediction only]; MoxR-like ATPase is part of the Pathway ...
 148-173 9.68e-04

MoxR-like ATPase [General function prediction only]; MoxR-like ATPase is part of the Pathway/BioSystem: Cobalamine/B12 biosynthesis


Pssm-ID: 440478 [Multi-domain]  Cd Length: 292  Bit Score: 40.54  E-value: 9.68e-04
                          10        20
                  ....*....|....*....|....*.
gi 1780599528 148 ILLFGPPGTGKTMLAKAVATECNTTF 173
Cdd:COG0714    34 LLLEGVPGVGKTTLAKALARALGLPF 59
ruvB TIGR00635
Holliday junction DNA helicase, RuvB subunit; All proteins in this family for which functions ...
 148-216 9.78e-04

Holliday junction DNA helicase, RuvB subunit; All proteins in this family for which functions are known are 5'-3' DNA helicases that, as part of a complex with RuvA homologs serve as a 5'-3' Holliday junction helicase. RuvA specifically binds Holliday junctions as a sandwich of two tetramers and maintains the configuration of the junction. It forms a complex with two hexameric rings of RuvB, the subunit that contains helicase activity. The complex drives ATP-dependent branch migration of the Holliday junction recombination intermediate. The endonuclease RuvC resolves junctions. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129721 [Multi-domain]  Cd Length: 305  Bit Score: 40.75  E-value: 9.78e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1780599528 148 ILLFGPPGTGKTMLAKAVATECNTTFFNISASSVVSKwrGDsekLIRVLFDLARHhapSTIFLDEIDAI 216
Cdd:TIGR00635  33 LLLYGPPGLGKTTLAHIIANEMGVNLKITSGPALEKP--GD---LAAILTNLEEG---DVLFIDEIHRL 93
3a01205 TIGR00956
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]
 107-183 1.03e-03

Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273362 [Multi-domain]  Cd Length: 1394  Bit Score: 41.25  E-value: 1.03e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528  107 PNIKW----ESIKGLENAKKLLKEAVVMPIkyptyfNGLLTPWKGILLFGPPGTGKTMLAKAVAteCNTTFFNISASSVV 182
Cdd:TIGR00956   51 PNALLkiltRGFRKLKKFRDTKTFDILKPM------DGLIKPGELTVVLGRPGSGCSTLLKTIA--SNTDGFHIGVEGVI 122


                   .
gi 1780599528  183 S 183
Cdd:TIGR00956  123 T 123
AAA_5 pfam07728
AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not ...
 147-272 1.30e-03

AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not detected by the pfam00004 model.


Pssm-ID: 400191 [Multi-domain]  Cd Length: 135  Bit Score: 38.81  E-value: 1.30e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528 147 GILLFGPPGTGKTMLAK--AVATECNTTFF-----NISASSVVSKWR---GDSEKLIRVLFDLARHhaPSTIFLDEIDai 216
Cdd:pfam07728   1 GVLLVGPPGTGKTELAErlAAALSNRPVFYvqltrDTTEEDLFGRRNidpGGASWVDGPLVRAARE--GEIAVLDEIN-- 76

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1780599528 217 isqrggegRSEHEASRRLKTEL----LIQMDG---LQKTNELVFVLAATNLP----WELDAAMLRRL 272
Cdd:pfam07728  77 --------RANPDVLNSLLSLLderrLLLPDGgelVKAAPDGFRLIATMNPLdrglNELSPALRSRF 135
PRK13341 PRK13341
AAA family ATPase;
149-213 1.71e-03

AAA family ATPase;


Pssm-ID: 237354 [Multi-domain]  Cd Length: 725  Bit Score: 40.42  E-value: 1.71e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528 149 LLFGPPGTGKTMLAKAVATECNTTFFNISAssVVSkwrGDSEklIRVLFDLAR----HHAPSTI-FLDEI 213
Cdd:PRK13341   56 ILYGPPGVGKTTLARIIANHTRAHFSSLNA--VLA---GVKD--LRAEVDRAKerleRHGKRTIlFIDEV 118
RNA_helicase pfam00910
RNA helicase; This family includes RNA helicases thought to be involved in duplex unwinding ...
 148-218 1.87e-03

RNA helicase; This family includes RNA helicases thought to be involved in duplex unwinding during viral RNA replication. Members of this family are found in a variety of single stranded RNA viruses.


Pssm-ID: 459992  Cd Length: 102  Bit Score: 37.58  E-value: 1.87e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1780599528 148 ILLFGPPGTGKTMLAKAVATECNTTfFNISASSVVSK------WRGDSEKLIRVLFDLARHhaPSTIFLDEIDAIIS 218
Cdd:pfam00910   1 IWLYGPPGCGKSTLAKYLARALLKK-LGLPKDSVYSRnpdddfWDGYTGQPVVIIDDFGQN--PDGPDEAELIRLVS 74
RuvB_N pfam05496
Holliday junction DNA helicase RuvB P-loop domain; The RuvB protein makes up part of the ...
 148-213 2.11e-03

Holliday junction DNA helicase RuvB P-loop domain; The RuvB protein makes up part of the RuvABC revolvasome which catalyzes the resolution of Holliday junctions that arise during genetic recombination and DNA repair. Branch migration is catalyzed by the RuvB protein that is targeted to the Holliday junction by the structure specific RuvA protein. This family contains the N-terminal region of the protein.


Pssm-ID: 398900 [Multi-domain]  Cd Length: 159  Bit Score: 38.64  E-value: 2.11e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1780599528 148 ILLFGPPGTGKTMLAKAVATECNTTfFNISASSVVSKwRGDsekLIRVLFDLARHhapSTIFLDEI 213
Cdd:pfam05496  36 VLLYGPPGLGKTTLANIIANEMGVN-IRITSGPAIER-PGD---LAAILTNLEPG---DVLFIDEI 93
RuvB COG2255
Holliday junction resolvasome RuvABC, ATP-dependent DNA helicase subunit RuvB [Replication, ...
 148-213 2.44e-03

Holliday junction resolvasome RuvABC, ATP-dependent DNA helicase subunit RuvB [Replication, recombination and repair];


Pssm-ID: 441856 [Multi-domain]  Cd Length: 337  Bit Score: 39.68  E-value: 2.44e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1780599528 148 ILLFGPPGTGKTMLAKAVATECNTtffNISASS--VVSKwRGDsekLIRVLFDLARHhapSTIFLDEI 213
Cdd:COG2255    57 VLLYGPPGLGKTTLAHIIANEMGV---NIRITSgpAIEK-PGD---LAAILTNLEEG---DVLFIDEI 114
RecA-like_superfamily cd01120
RecA-like_NTPases; RecA-like NTPases. This superfamily includes the NTP binding domain of F1 ...
 148-227 5.84e-03

RecA-like_NTPases; RecA-like NTPases. This superfamily includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410865 [Multi-domain]  Cd Length: 119  Bit Score: 36.33  E-value: 5.84e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528 148 ILLFGPPGTGKTMLAKAVATE-CNTTFFNISASSVvskwrgdsEKLIRVLFDLARHHAPSTIFLDEIDAIISQRGGEGRS 226
Cdd:cd01120     1 ILITGPPGSGKTTLLLQFAEQaLLSDEPVIFISFL--------DTILEAIEDLIEEKKLDIIIIDSLSSLARASQGDRSS 72


                  .
gi 1780599528 227 E 227
Cdd:cd01120    73 E 73
IS21_help_AAA NF038214
IS21-like element helper ATPase IstB; This protein family model resembles PF01695, but was ...
 148-169 5.88e-03

IS21-like element helper ATPase IstB; This protein family model resembles PF01695, but was built to hit full-length AAA+ ATPases of IS21 family IS (insertion sequence) elements.


Pssm-ID: 439516  Cd Length: 232  Bit Score: 37.84  E-value: 5.88e-03
                          10        20
                  ....*....|....*....|..
gi 1780599528 148 ILLFGPPGTGKTMLAKAVATEC 169
Cdd:NF038214   93 VLLLGPPGTGKTHLAIALGYAA 114
DYN1 COG5245
Dynein, heavy chain [Cytoskeleton];
111-161 7.90e-03

Dynein, heavy chain [Cytoskeleton];


Pssm-ID: 227570 [Multi-domain]  Cd Length: 3164  Bit Score: 38.82  E-value: 7.90e-03
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1780599528  111 WESIKG--LENAKKLLKEAVVMP----IKYPTYFNGLLTPWKGILLFGPPGTGKTML 161
Cdd:COG5245   1454 NGSIAGfeLRGERVMLRKEVVIPtsdtGFVDSFSNEALNTLRSYIYCGPPGSGKEML 1510
PRK04195 PRK04195
replication factor C large subunit; Provisional
 144-168 8.27e-03

replication factor C large subunit; Provisional


Pssm-ID: 235250 [Multi-domain]  Cd Length: 482  Bit Score: 38.36  E-value: 8.27e-03
                          10        20
                  ....*....|....*....|....*
gi 1780599528 144 PWKGILLFGPPGTGKTMLAKAVATE 168
Cdd:PRK04195   38 PKKALLLYGPPGVGKTSLAHALAND 62
PspF COG1221
Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain ...
 117-164 8.34e-03

Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain [Transcription, Signal transduction mechanisms];


Pssm-ID: 440834 [Multi-domain]  Cd Length: 835  Bit Score: 38.55  E-value: 8.34e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 1780599528 117 LENAKKLLKEAvvmpIKYPTyfNGLLTpwkgiLLFGPPGTGKTMLAKA 164
Cdd:COG1221   113 LKNAIEQAKAA----ILYPP--KGLHT-----LILGPTGVGKSFFAEL 149
RecA-like_ClpB_Hsp104-like cd19499
Chaperone protein ClpB/Hsp104 subfamily; Bacterial Caseinolytic peptidase B (ClpB) and ...
 147-214 9.13e-03

Chaperone protein ClpB/Hsp104 subfamily; Bacterial Caseinolytic peptidase B (ClpB) and eukaryotic Heat shock protein 104 (Hsp104) are ATP-dependent molecular chaperones and essential proteins of the heat-shock response. ClpB/Hsp104 ATPases, in concert with the DnaK/Hsp70 chaperone system, disaggregate and reactivate aggregated proteins. This RecA-like_ClpB_Hsp104_like subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410907 [Multi-domain]  Cd Length: 178  Bit Score: 36.77  E-value: 9.13e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528 147 GILLF-GPPGTGKTMLAKAVA-----TECNTTFFNISASSvvskWRGDSEKLIR------------VLFDLARHHAPSTI 208
Cdd:cd19499    42 GSFLFlGPTGVGKTELAKALAellfgDEDNLIRIDMSEYM----EKHSVSRLIGappgyvgyteggQLTEAVRRKPYSVV 117


                  ....*.
gi 1780599528 209 FLDEID 214
Cdd:cd19499   118 LLDEIE 123
RecA-like_ClpX cd19497
ATP-dependent Clp protease ATP-binding subunit ClpX; ClpX is a component of the ATP-dependent ...
 116-216 9.31e-03

ATP-dependent Clp protease ATP-binding subunit ClpX; ClpX is a component of the ATP-dependent protease ClpXP. In ClpXP, ClpX ATPase serves to specifically recognize, unfold, and translocate protein substrates into the chamber of ClpP protease for degradation. This RecA-like_ClpX domain subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410905 [Multi-domain]  Cd Length: 251  Bit Score: 37.58  E-value: 9.31e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1780599528 116 GLENAKKLLKEAVvmpikYPTY---FNGLLTPWKG-------ILLFGPPGTGKTMLAKAVATECNTTFFNISASSV---- 181
Cdd:cd19497    16 GQERAKKVLSVAV-----YNHYkriRNNLKQKDDDveleksnILLIGPTGSGKTLLAQTLAKILDVPFAIADATTLteag 90

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 1780599528 182 -VSKwrgDSEKLI-RVL----FDLARHHApSTIFLDEIDAI 216
Cdd:cd19497    91 yVGE---DVENILlKLLqaadYDVERAQR-GIVYIDEIDKI 127
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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