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Conserved domains on  [gi|1790608791|emb|VUH54197|]
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inner membrane protein [Klebsiella pneumoniae]

Protein Classification

FUSC family protein( domain architecture ID 11441727)

FUSC family protein containing a fusaric acid resistance protein (FUSC_2) domain; may be involved in membrane transport

Gene Ontology:  GO:0055085|GO:0022857|GO:0005886
TCDB:  2.A.85

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
YccC COG1289
Uncharacterized membrane protein YccC [Function unknown];
16-247 3.11e-43

Uncharacterized membrane protein YccC [Function unknown];


:

Pssm-ID: 440900 [Multi-domain]  Cd Length: 280  Bit Score: 150.93  E-value: 3.11e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1790608791  16 RHYRVVHGVRIALAFVLTFLLVRLLNVPEGTWPLITLVVVMGPisFWGNVVPRAFQRIGGTILGSALGLVALKLeLISLP 95
Cdd:COG1289    43 DSPAFRHALRLALAALLALLIALLLGLPHPYWALLTVLIVLQP--SYGATLSRALQRILGTLLGALAGLLLLAL-FPQPL 119
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1790608791  96 LMVLWCAAAMFLCgWLALGKKPYQALLIGITLSVVVGAP---PGDMHTALWRSGDVIFGSLLAMLFTG-IWPQRAFIHWR 171
Cdd:COG1289   120 LLLLALALVLGLC-FFALLTRSYAFALAGITAAVVLLFAllgPGVFDVALARVLDTLIGILIALLVSYlLWPRWARRRLR 198
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1790608791 172 IQMASYVTNFNRLYQAGFSP-NLVDRPRLEKHLQQALNDVVKMRGLITPASKET-HIQKAIFEAIQTVSRNLVCMLEL 247
Cdd:COG1289   199 ARLARALRANARYLRALLSQgDPADDLALRAARRRLAAALAALEALLQRALSEPpRGRRRELRALLALNHRLLSLLSA 276
 
Name Accession Description Interval E-value
YccC COG1289
Uncharacterized membrane protein YccC [Function unknown];
16-247 3.11e-43

Uncharacterized membrane protein YccC [Function unknown];


Pssm-ID: 440900 [Multi-domain]  Cd Length: 280  Bit Score: 150.93  E-value: 3.11e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1790608791  16 RHYRVVHGVRIALAFVLTFLLVRLLNVPEGTWPLITLVVVMGPisFWGNVVPRAFQRIGGTILGSALGLVALKLeLISLP 95
Cdd:COG1289    43 DSPAFRHALRLALAALLALLIALLLGLPHPYWALLTVLIVLQP--SYGATLSRALQRILGTLLGALAGLLLLAL-FPQPL 119
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1790608791  96 LMVLWCAAAMFLCgWLALGKKPYQALLIGITLSVVVGAP---PGDMHTALWRSGDVIFGSLLAMLFTG-IWPQRAFIHWR 171
Cdd:COG1289   120 LLLLALALVLGLC-FFALLTRSYAFALAGITAAVVLLFAllgPGVFDVALARVLDTLIGILIALLVSYlLWPRWARRRLR 198
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1790608791 172 IQMASYVTNFNRLYQAGFSP-NLVDRPRLEKHLQQALNDVVKMRGLITPASKET-HIQKAIFEAIQTVSRNLVCMLEL 247
Cdd:COG1289   199 ARLARALRANARYLRALLSQgDPADDLALRAARRRLAAALAALEALLQRALSEPpRGRRRELRALLALNHRLLSLLSA 276
FUSC_2 pfam13515
Fusaric acid resistance protein-like;
32-158 3.93e-14

Fusaric acid resistance protein-like;


Pssm-ID: 433273 [Multi-domain]  Cd Length: 126  Bit Score: 68.42  E-value: 3.93e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1790608791  32 LTFLLVRLLNVPEGTWPLITLVVVMGPisFWGNVVPRAFQRIGGTILGSALGLVALKLELISLPLmvlwcAAAMFLCGWL 111
Cdd:pfam13515   1 LAALIAELLGLPRGYWAPIAAAIVLQP--TLGATLRRAVQRILGTVLGVLLGLLLLALLPGPLQL-----ILVVALLGFL 73
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1790608791 112 A--LGKKPYQALLIGITLSVVVGA----PPGDMHTALWRSGDVIFGSLLAMLF 158
Cdd:pfam13515  74 AeyLIGRNYALAQVFVTPLALLLAslagGGGPPELALLRILDTLIGALIALLV 126
 
Name Accession Description Interval E-value
YccC COG1289
Uncharacterized membrane protein YccC [Function unknown];
16-247 3.11e-43

Uncharacterized membrane protein YccC [Function unknown];


Pssm-ID: 440900 [Multi-domain]  Cd Length: 280  Bit Score: 150.93  E-value: 3.11e-43
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1790608791  16 RHYRVVHGVRIALAFVLTFLLVRLLNVPEGTWPLITLVVVMGPisFWGNVVPRAFQRIGGTILGSALGLVALKLeLISLP 95
Cdd:COG1289    43 DSPAFRHALRLALAALLALLIALLLGLPHPYWALLTVLIVLQP--SYGATLSRALQRILGTLLGALAGLLLLAL-FPQPL 119
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1790608791  96 LMVLWCAAAMFLCgWLALGKKPYQALLIGITLSVVVGAP---PGDMHTALWRSGDVIFGSLLAMLFTG-IWPQRAFIHWR 171
Cdd:COG1289   120 LLLLALALVLGLC-FFALLTRSYAFALAGITAAVVLLFAllgPGVFDVALARVLDTLIGILIALLVSYlLWPRWARRRLR 198
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1790608791 172 IQMASYVTNFNRLYQAGFSP-NLVDRPRLEKHLQQALNDVVKMRGLITPASKET-HIQKAIFEAIQTVSRNLVCMLEL 247
Cdd:COG1289   199 ARLARALRANARYLRALLSQgDPADDLALRAARRRLAAALAALEALLQRALSEPpRGRRRELRALLALNHRLLSLLSA 276
FUSC_2 pfam13515
Fusaric acid resistance protein-like;
32-158 3.93e-14

Fusaric acid resistance protein-like;


Pssm-ID: 433273 [Multi-domain]  Cd Length: 126  Bit Score: 68.42  E-value: 3.93e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1790608791  32 LTFLLVRLLNVPEGTWPLITLVVVMGPisFWGNVVPRAFQRIGGTILGSALGLVALKLELISLPLmvlwcAAAMFLCGWL 111
Cdd:pfam13515   1 LAALIAELLGLPRGYWAPIAAAIVLQP--TLGATLRRAVQRILGTVLGVLLGLLLLALLPGPLQL-----ILVVALLGFL 73
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1790608791 112 A--LGKKPYQALLIGITLSVVVGA----PPGDMHTALWRSGDVIFGSLLAMLF 158
Cdd:pfam13515  74 AeyLIGRNYALAQVFVTPLALLLAslagGGGPPELALLRILDTLIGALIALLV 126
YgaE COG4129
Uncharacterized membrane protein YgaE, UPF0421/DUF939 family [Function unknown];
24-187 1.42e-10

Uncharacterized membrane protein YgaE, UPF0421/DUF939 family [Function unknown];


Pssm-ID: 443305 [Multi-domain]  Cd Length: 197  Bit Score: 60.00  E-value: 1.42e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1790608791  24 VRIALAFVLTFLLVRLLNVPEGTWPLITLVVVMGPiSFWGNVVpRAFQRIGGTILGSALGLVALKL---ELISLPLMVLw 100
Cdd:COG4129    15 LKTALAAALAWLIAELLGLPYPFFAAIAAVLCLQP-TVGRSLR-RALERILGVLIGALVGVLFFLLlgyGPWQLGLAVL- 91
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1790608791 101 caAAMFLCGWLALGkkpYQALLIGITLSVVV--GAPPGDMHTALWRSGDVIFGSLLAMLFT-GIWPQRAFIHWRIQMASY 177
Cdd:COG4129    92 --LAILLAVLLKLG---EGIVLAAVTALLVLllGSPDDSLGYALNRLLDTLIGVGVALLVNlLLLPPDPERRLRRAAAEL 166
                         170
                  ....*....|
gi 1790608791 178 VTNFNRLYQA 187
Cdd:COG4129   167 LEELADILRE 176
FUSC pfam04632
Fusaric acid resistance protein family; This family includes a conserved region found in two ...
20-351 8.38e-10

Fusaric acid resistance protein family; This family includes a conserved region found in two proteins associated with fusaric acid resistance, from Burkholderia cepacia and Klebsiella oxytoca. These proteins are likely to be membrane transporter proteins.


Pssm-ID: 428044 [Multi-domain]  Cd Length: 655  Bit Score: 59.99  E-value: 8.38e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1790608791  20 VVHGVRIALAFVLTFLLVRLLNVPEGTWPLITLVVVMGPISfwGNVVPRAFQRIGGTILGSALGLVALKLELISLPLMVL 99
Cdd:pfam04632   1 WLFALKTFLAAMLALYIALRLELPQPYWAMTTVFIVSQPLS--GAVLSKSFYRLLGTLVGAAAAVLLVALFVQAPLLFLL 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1790608791 100 WCAAAMFLCGWLAL---GKKPYQALLIGITLSVV----VGAPPGDMHTALWRSGDVIFGSLLAMLFTGI-WPQRAFIHWR 171
Cdd:pfam04632  79 ALALWIGLCLALSLldrNFRSYAFVLAGYTAAIIglpaVADPEAIFDIAVARVSEISLGILCAALVSALvFPRSVGPALR 158
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1790608791 172 IQMASYVTNFNRLYQAGFSPNLvDRPRLEKHLQQALNDVVKMRGLITPASKET-HIQKAIFEAIQTVSRNLVCMLELQIN 250
Cdd:pfam04632 159 ARLRARLRDALRLAAAALAGAP-GAEAFEAARLRLAADILALEALRSHAAFESpRGRARARALRRLLARMLALLPRLRSL 237
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1790608791 251 AW-WATRPGHfvmlNAHTLRETQQMTQQTLLSIAHALYEGNPQPVRAnneklteivleLRQLLKEQGDDGLAETPVHGYV 329
Cdd:pfam04632 238 ARlLARLRTE----GAGTVPELAALLDELAAWEAALAAEALQAALAA-----------LRARLRALRPALPLDFDTAAEL 302
                         330       340
                  ....*....|....*....|....*..
gi 1790608791 330 WlsielARQLELLSHLI-----CRALR 351
Cdd:pfam04632 303 L-----ARLADLLAELAealasCRALR 324
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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