Lantibiotic macedocin [Streptococcus pyogenes]
Protein Classification
similar to lantibiotic nukacin( domain architecture ID 10519119)
protein similar to lantibiotic nukacin
List of domain hits
| Name | Accession | Description | Interval | E-value | ||
| L_biotic_typeA | pfam04604 | Type-A lantibiotic; Lantibiotics are antibiotic peptides distinguished by the presence of the ... |
1-50 | 4.79e-21 | ||
Type-A lantibiotic; Lantibiotics are antibiotic peptides distinguished by the presence of the rare thioether amino acids lanthionine and/or methyl-lanthionine. They are produced by Gram-positive bacteria as gene-encoded precursor peptides and undergo post-translational modification to generate the mature peptide. Based on their structural and functional features lantibiotics are currently divided into two major groups: the flexible amphiphilic type-A and the rather rigid and globular type-B. Type-A lantibiotics act primarily by pore formation in the bacterial membrane by a mechanism involving the interaction with specific docking molecules such as the membrane precursor lipid II. : Pssm-ID: 368018 Cd Length: 51 Bit Score: 76.28 E-value: 4.79e-21
|
||||||
| Name | Accession | Description | Interval | E-value | ||
| L_biotic_typeA | pfam04604 | Type-A lantibiotic; Lantibiotics are antibiotic peptides distinguished by the presence of the ... |
1-50 | 4.79e-21 | ||
Type-A lantibiotic; Lantibiotics are antibiotic peptides distinguished by the presence of the rare thioether amino acids lanthionine and/or methyl-lanthionine. They are produced by Gram-positive bacteria as gene-encoded precursor peptides and undergo post-translational modification to generate the mature peptide. Based on their structural and functional features lantibiotics are currently divided into two major groups: the flexible amphiphilic type-A and the rather rigid and globular type-B. Type-A lantibiotics act primarily by pore formation in the bacterial membrane by a mechanism involving the interaction with specific docking molecules such as the membrane precursor lipid II. Pssm-ID: 368018 Cd Length: 51 Bit Score: 76.28 E-value: 4.79e-21
|
||||||
| HEC_x9_TCC_lant | NF040664 | lacticin 481 family lantibiotic; The lacticin 481 group exert their antimicrobial action by ... |
12-50 | 5.56e-20 | ||
lacticin 481 family lantibiotic; The lacticin 481 group exert their antimicrobial action by disrupting the cytoplasmic membrane. This model contains a lipid II-binding motif. The docking of the lantibiotic with lipid II is part of the mechanism by which family members form a membrane-disrupting structure. The lacticin 481 group includes lacticin 481, mutacin H-29B, variacin, nukacin ISK-1, butyrivibriocin OR79A, streptococcin A-FF2, ruminococcin A, mutacin II, and salivaricin A. Pssm-ID: 468630 Cd Length: 39 Bit Score: 73.50 E-value: 5.56e-20
|
||||||
| Name | Accession | Description | Interval | E-value | ||
| L_biotic_typeA | pfam04604 | Type-A lantibiotic; Lantibiotics are antibiotic peptides distinguished by the presence of the ... |
1-50 | 4.79e-21 | ||
Type-A lantibiotic; Lantibiotics are antibiotic peptides distinguished by the presence of the rare thioether amino acids lanthionine and/or methyl-lanthionine. They are produced by Gram-positive bacteria as gene-encoded precursor peptides and undergo post-translational modification to generate the mature peptide. Based on their structural and functional features lantibiotics are currently divided into two major groups: the flexible amphiphilic type-A and the rather rigid and globular type-B. Type-A lantibiotics act primarily by pore formation in the bacterial membrane by a mechanism involving the interaction with specific docking molecules such as the membrane precursor lipid II. Pssm-ID: 368018 Cd Length: 51 Bit Score: 76.28 E-value: 4.79e-21
|
||||||
| HEC_x9_TCC_lant | NF040664 | lacticin 481 family lantibiotic; The lacticin 481 group exert their antimicrobial action by ... |
12-50 | 5.56e-20 | ||
lacticin 481 family lantibiotic; The lacticin 481 group exert their antimicrobial action by disrupting the cytoplasmic membrane. This model contains a lipid II-binding motif. The docking of the lantibiotic with lipid II is part of the mechanism by which family members form a membrane-disrupting structure. The lacticin 481 group includes lacticin 481, mutacin H-29B, variacin, nukacin ISK-1, butyrivibriocin OR79A, streptococcin A-FF2, ruminococcin A, mutacin II, and salivaricin A. Pssm-ID: 468630 Cd Length: 39 Bit Score: 73.50 E-value: 5.56e-20
|
||||||
| Blast search parameters | ||||
|
