|
Name |
Accession |
Description |
Interval |
E-value |
| MATE_MepA_like |
cd13143 |
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to ... |
12-417 |
4.72e-85 |
|
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Streptococcus aureus MepA; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. This subfamily includes Streptococcus aureus MepA and Vibrio vulnificus VmrA and functions most likely as a multidrug efflux pump.
Pssm-ID: 240548 [Multi-domain] Cd Length: 426 Bit Score: 267.45 E-value: 4.72e-85
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 12 PQLIRFTLPTIGMMLFMSLYVMVDGFFVSNWCGQTALAAVNFAYPIPMILGTLGFMFGTGGSAIVAKTRGEGDDARANRQ 91
Cdd:cd13143 4 KLFLKFALPAIIGMLVNGLYNIVDGIFVGHGVGALALAAVNLVFPIIMLLMALGLMIGVGGASLISRRLGAGDREKANRI 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 92 FSLLVYAAIVAGAAFAALGVLLLRPLLVALGAQGEMLDLCMVYAMPLVMGVPATVLQYLFQELLVTAGKPELGFGVTVAA 171
Cdd:cd13143 84 FSTALLLSLILGLLLTILGLLFLDPLLRLLGASGELLPYAVDYLRIILLGAPFTILSSVLNNLLRAEGKPKLAMLGMLIG 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 172 GLTNIVVDAVLIALLDFGVVGAAIGTIAGEAVGGIIPLVYFARPNKSF-LRLGRTNMDWRMLGHACVNGSSEMVSNIAMS 250
Cdd:cd13143 164 AVLNIILDPLFIFVLGLGIAGAALATVIAQLISLLLLLLYFFRGKSLLkLSLLRFKLSLKIIKEILALGFPSFLMQLSSS 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 251 LVSMAYNVQLLVYLGESGVAAYGVIMYVGMAFVAVFMGYVFGSSPLMSFQYGANNRIEMRSLFRKSLLFVSICGVAMFIA 330
Cdd:cd13143 244 VVTIVLNLTLLGYGGDIGVAAFGIVTRILTFLFLPLIGLSQGLQPIIGYNYGAGNYDRVKQALKLALIVALIYGLVLFLI 323
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 331 TRVFARPLALVFVGYSEgLAELTVHAMLLYSASLLIVGFNMYGSALFTALGNGLVSAIISFVRTLIFEIGAVFLLPTLFG 410
Cdd:cd13143 324 LLLFPEQIVSLFTDDPE-LIALAARILRIFLLAFPLAGINIVLSGYFQAIGKAKRAALLSLLRQGLFLIPLLLILPRLFG 402
|
....*..
gi 1540040113 411 ADGIWVS 417
Cdd:cd13143 403 LDGIWLA 409
|
|
| NorM |
COG0534 |
Na+-driven multidrug efflux pump, DinF/NorM/MATE family [Defense mechanisms]; |
5-417 |
1.10e-66 |
|
Na+-driven multidrug efflux pump, DinF/NorM/MATE family [Defense mechanisms];
Pssm-ID: 440300 [Multi-domain] Cd Length: 427 Bit Score: 219.63 E-value: 1.10e-66
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 5 MSRHFTLPQLIRFTLPTIGMMLFMSLYVMVDGFFVSnWCGQTALAAVNFAYPIPMILGTLGFMFGTGGSAIVAKTRGEGD 84
Cdd:COG0534 1 LTEGPILKLLLRLALPIILGNLLQSLYGLVDTIFVG-RLGTAALAAVGLAFPIFFLLIALGIGLGVGGTALVAQALGAGD 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 85 DARANRQFSLLVYAAIVAGAAFAALGVLLLRPLLVALGAQGEMLDLCMVYAMPLVMGVPATVLQYLFQELLVTAGKPELG 164
Cdd:COG0534 80 REEARRVLGQALLLALLLGLLLTLLGLLFAPPLLRLLGADPEVLALARDYLRIILLGLPFLLLFNVLNGILRGLGDTKTP 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 165 FGVTVAAGLTNIVVDAVLIALLDFGVVGAAIGTIAGEAVGGIIPLVYFARPNKSF-LRLGRTNMDWRMLGHACVNGSSEM 243
Cdd:COG0534 160 MIIMLIGNVLNIVLDPLLIFGGGLGVAGAALATVISQAVSALLLLYYLFRKRSLLrLRLRDLRPDRKILKRILRIGLPAG 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 244 VSNIAMSLVSMAYNVQLLVYlGESGVAAYGVIMYVGMAFVAVFMGYVFGSSPLMSFQYGANNRIEMRSLFRKSLLFVSIC 323
Cdd:COG0534 240 LQQLAESLGFLVLNALVARL-GTAAVAAYGIALRIESLAFMPALGLGQAAQPLVGQNLGAGDYDRARRAARLALLLALGI 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 324 GVAMFIATRVFARPLALVFVGySEGLAELTVHAMLLYSASLLIVGFNMYGSALFTALGNGLVSAIISFVRTLIFEIGAVF 403
Cdd:COG0534 319 GLLLALLLFLFPEPIIGLFTD-DPEVIALAATYLRIAALFQPFDGLQFVLSGALRGAGDTRFPMIISLLRLWLVRLPLAY 397
|
410
....*....|....*
gi 1540040113 404 LLP-TLFGADGIWVS 417
Cdd:COG0534 398 LLAfLGLGLTGVWLA 412
|
|
| vmrA |
PRK09575 |
MATE family efflux transporter; |
13-417 |
2.48e-39 |
|
MATE family efflux transporter;
Pssm-ID: 236576 [Multi-domain] Cd Length: 453 Bit Score: 147.45 E-value: 2.48e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 13 QLIRFTLPTIGMMLFMSLYVMVDGFFVSNWCGQTALAAVNFAYPIPMILGTLGFMFGTGGSAIVAKTRGEGDDARANRQF 92
Cdd:PRK09575 13 TFWRYTIPSIAAMLVNGLYQIVDGIFIGHYVGAEGLAGINMAWPVIGIILGIGLMVGMGTGSLLSIKRGEGDLEKAKRIL 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 93 SLLVYAAIVAGAAFAALGVLLLRPLLVALGAQGEMLDLCMVYAMPLVMGVPATVLQYLFQELLVTAGKPELGFGVTVAAG 172
Cdd:PRK09575 93 TTGLLLLLLLGPIVSVILFLFADDFLRAQGAEGRTLELALQYIQVLIWGCLFTLGAIALPFLLRNDESPNLATGLMVIGA 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 173 LTNIVVDAVLIALLDFGVVGAAIGTIAGEAVGGIIPLVYF-ARPNKSFLRLGRTNMDWRMLGHACVNGSSEMVSNIAMSL 251
Cdd:PRK09575 173 LINIVLDYLFIGWLDWGLTGAAIATALAQLVVTVLGLGYFfSSRANIRLTLKELRFNWSLAPKIVLLGSSSFFMYLYGSF 252
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 252 VSMAYNVQLLVYLGESGVAAYGVIMYVGMAFVAVFMGYVFGSSPLMSFQYGANNRIEMRSLFRKSLLFVSICGVAMFIAT 331
Cdd:PRK09575 253 VVALHNRLFMEYGSALTVGAYAIVGYLMVLYYLVAEGIAEGMQPPVSYYFGARQYDNIKKLLKLAMKVTVLAGIAWVLLL 332
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 332 RVFARPLALVFVGYSEGLAELTVHAMLLYSASLLIVGFNMYGSALFTALGNGLVSAIISFVRTLIfEIGAVFLLPTLFGA 411
Cdd:PRK09575 333 NLFPETMIALFNSGDSELIAETIVGIRLHLFAMFLDGFLVLASAYFMAVNQGGKALFISIGNMLI-QLPFLFILPKWLGV 411
|
....*.
gi 1540040113 412 DGIWVS 417
Cdd:PRK09575 412 DGVWLA 417
|
|
| MATE_yoeA_like |
cd13138 |
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to ... |
11-417 |
1.84e-37 |
|
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Bacillus subtilis yoeA; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240543 [Multi-domain] Cd Length: 431 Bit Score: 141.83 E-value: 1.84e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 11 LPQLIRFTLPTIGMMLFMSLYVMVDGFFVSNWCGQTALAAVNFAYPIPMILGTLGFMFGTGGSAIVAKTRGEGDDARANR 90
Cdd:cd13138 2 LKTLLLFALPLLLSNLLQQLYNLVDLLIVGQFLGVAALAAVSNGSPIIFLLTAIGMGLSMGGTILISQYIGAKDEEKAKK 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 91 QFSLLVYAAIVAGAAFAALGVLLLRPLLVALGAQGEMLDLCMVYAMPLVMGVPATVLQYLFQELLVTAGKPELGFGVTVA 170
Cdd:cd13138 82 AVGTLLVLFLILGIVLTILGLLFAPPILRLMNTPAEILELAVSYLRICFLGIPFIFGYNAYSAILRGLGDSKTPLYFVII 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 171 AGLTNIVVDAVLIALLDFGVVGAAIGTIAGEAVGGIIPLVYFARPNKSF-LRLGRTNMDWRMLGHACVNGSSEMVSNIAM 249
Cdd:cd13138 162 ACVLNIILDLLFIAVFHMGVAGAALATVIAQAISVLLALYYLRKKKLPFkLSLKDFRFDKEILKEILKIGLPSALQQSLV 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 250 SLVSMAYNVQLLVYlGESGVAAYGVIMYVGMAFVAVFMGYVFGSSPLMSFQYGANNRIEMRSLFRKSLLFVSICGVAMFI 329
Cdd:cd13138 242 SISFLIINSIVNSY-GVVASAAYGIANKINSFAFLPPSAIGQAVSTFVAQNIGAGKIERAKKGLRTGIIISLIIGLIIIL 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 330 ATRVFARPLALVFVGySEGLAELTVHAMLLYSASLLIVGFNMYGSALFTALGNGLVSAIISFVRTLIFEIGAVFLLPTLF 409
Cdd:cd13138 321 LVFFFAPQLLGLFTS-DPEVIEIGAEYLRIYSIDYILFGILFVFNGLFRGLGKTKFPMIISILRLWLVRIPLAYLLSRLT 399
|
410
....*....|
gi 1540040113 410 --GADGIWVS 417
Cdd:cd13138 400 glGLFGIWLA 409
|
|
| MATE_like_4 |
cd13144 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
11-417 |
5.27e-34 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240549 [Multi-domain] Cd Length: 434 Bit Score: 132.36 E-value: 5.27e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 11 LPQLIRFTLPTIGMMLFMSLYVMVDGFFVSnWCGQTALAAVNFAYPIPMILGTLGFMFGTGGSAIVAKTRGEGDDARANR 90
Cdd:cd13144 7 LRLLLTMSIPAMISMLFQALYNIVDSIFVA-RLGENALTAVSLAFPIQNLMIAVAVGTGVGVNALLSRSLGEKDQKEANK 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 91 QFSLLVYAAIVAGAAFAALGVLLLRPLLVALGAQGEMLDLCMVYAMPLVMGVPATVLQYLFQELLVTAGKPELGFGVTVA 170
Cdd:cd13144 86 AANNGLLLALLSYLLFLLLGLFGVKPFFRLFTDDPEILEYGYAYLSWCVIFSFGMFFQILCEKVLQSTGNTITPMIAQLI 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 171 AGLTNIVVDAVLI----ALLDFGVVGAAIGTIAGEAVGGIIPLVYFARPNK-SFLRLGRTNMDWRMLGHACVNGSSEMVS 245
Cdd:cd13144 166 GAIINIILDPILIfglfGFPAMGIAGAAIATVIGQILAMFLAFFFLLRKNKdVQPDLRLFRPSLRIIKEIYAVGLPSIIM 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 246 NIAMSLVSMAYNVQLLVYlGESGVAAYGVIMYV-GMAFVAVFmGYVFGSSPLMSFQYGANNRIEMRSLFRKSLLFVSICG 324
Cdd:cd13144 246 QAISSVMVFGLNKILAGF-GPTAVAVFGIYFKLqSFVFMPVF-GLNNGLIPIVAYNYGAGNKDRIREAIKYAILIAVVIM 323
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 325 VAMFIATRVFARPLALVFVGySEGLAELTVHAMLLYSASLLIVGFNMYGSALFTALGNGLVSAIISFVRTLIFEIGAVFL 404
Cdd:cd13144 324 LAGGLLFQLFPDQLLGLFNA-SEEMLAIGVPALRIISLSFLFAALSIILSGLFQALGRGVYSLIISVARQLVVLLPLAWL 402
|
410
....*....|...
gi 1540040113 405 LPTLFGADGIWVS 417
Cdd:cd13144 403 LAKMFGLNGVWWS 415
|
|
| MATE_like |
cd12082 |
Multidrug and toxic compound extrusion family and similar proteins; The integral membrane ... |
19-415 |
1.59e-32 |
|
Multidrug and toxic compound extrusion family and similar proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. MATE has also been identified as a large multigene family in plants, where the proteins are linked to disease resistance. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240527 [Multi-domain] Cd Length: 420 Bit Score: 127.83 E-value: 1.59e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 19 LPTIGMMLFMSLYVMVDGFFVSNWcGQTALAAVNFAYPIPMILGTLGFMFGTGGSAIVAKTRGEGDDARANRQFSLLVYA 98
Cdd:cd12082 2 APLLLSMLLQTLYNLVDTFFLGRL-LGDALAAVGLAFPLIALLIALGVGLSVGTSALISQAIGAGDEEKARRVLVQSIVL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 99 AIVAGAAFAALGVLLLRPLLVALGAQGEMLDLCMVYAMPLVMGVPATVLQYLFQELLVTAGKPELGFGVTVAAGLTNIVV 178
Cdd:cd12082 81 AILLGLLLAALLLFFSPLILSLLGAEEEVIELAATYLTILILGLPITFLGAVLSGILQGEGDTRTAMIISVLSNLLNILL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 179 DAVLIALL---DFGVVGAAIGTIAGEAVGGIIPLVYFARPNKSFLRLGRTN-MDWRMLGHACVNGSSEMVSNIAMSLVSM 254
Cdd:cd12082 161 DPLLIFGLgppELGIAGAALATVISYVIGALLLLIYLRKGKKILKFKLSLLkPDLELLRRLLRIGLPSAIQNSLLSLGLL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 255 AYNVQLLVYLGESGVAAYGVIMYVGMAFVAVFMGYVFGSSPLMSFQYGANNRIEMRSLFRKSLLFVSICGVAMFIATRVF 334
Cdd:cd12082 241 IIVAIVAAFGGAAALAAYTVAFRIASLAFMPALGLAQAALPVVGQNLGAGNFDRARRITWVALLIGLLIGAVLGLLILLF 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 335 ARPLALVFVGYSEGLaELTVHAMLLYSASLLIVGFNMYGSALFTALGNGLVSAIISFVRTLIFEIGAVFLLPTL-FGADG 413
Cdd:cd12082 321 PEPILSLFTNDPEFL-ELAVSYLRILAIYYLFVGIGYVLQAGFQAAGRTLKSLIVSLLSYWVVRLPLAYVLAYLgLGLYG 399
|
..
gi 1540040113 414 IW 415
Cdd:cd12082 400 IW 401
|
|
| MATE_MJ0709_like |
cd13147 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins, ... |
14-416 |
5.98e-32 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins, similar to Methanocaldococcus jannaschii MJ0709; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240552 [Multi-domain] Cd Length: 441 Bit Score: 126.50 E-value: 5.98e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 14 LIRFTLPTIGMMLFMSLYVMVDGFFVSNwCGQTALAAVNFAYPIPMILGTLGFMFGTGGSAIVAKTRGEGDDARANRQFS 93
Cdd:cd13147 11 IIKLSIPMIIAMLLQTLYNLVDAIWVAG-LGADALAAIGFVFPLFMIIIGLGNGLGAGASSAISRRIGAKDKEGADNAAV 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 94 LLVYAAIVAGAAFAALGVLLLRPLLVALGAqGEMLDLCMVYAMPLVMGVPATVLQYLFQELLVTAGKPELGFGVTVAAGL 173
Cdd:cd13147 90 HSILLGLIISIILTIVLLPFLEPILVLMGA-GEVLDLAVDYGRIIFLGSIFLIFNNVAYGILRGEGDTKRAMYAMVAGSI 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 174 TNIVVDAVLIALLDFGVVGAAIGTIAGEAVGGIIPLVYFARPNKSFLRLGRTNM--DWRMLGHACVNGSSEMVSNIAMSL 251
Cdd:cd13147 169 LNIILDPIFIYTLGLGIAGAAWATVISMLISSLVLLYWFFVKKDTYVSLSLKNFkfDKKIVKDILKVGIPASLEQLIMSV 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 252 VSMAYNVQLLVYLGESGVAAYGVIMYVGMAFVAVFMGYVFGSSPLMSFQYGANNRIEMRSLFRKSLLFVSICGVAMFIAT 331
Cdd:cd13147 249 LMIILNLILVIVAGTDGVAVYTAGWRIVSFAIIPLIGIATAVTSVTGAAYGARNYEKLKTAYNYSIKLGLIIELIIAILI 328
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 332 RVFARPLALVF--VGYSEGLAELTVHAMLLYSASLLIVGFNMYGSALFTALGNGLVSAIISFVRTLIFEIGAVFLL--PT 407
Cdd:cd13147 329 FIFAPQIAYLFtySEESAHLAPEIVAFLRIMCLFLPFVPFGMMSSSMFQGIGKGLTSLIITILRELIFQVLFAYLFaiVL 408
|
....*....
gi 1540040113 408 LFGADGIWV 416
Cdd:cd13147 409 GLGLFGVWW 417
|
|
| MATE_NorM_like |
cd13137 |
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to ... |
13-417 |
5.80e-27 |
|
Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Thermotoga marina NorM; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240542 [Multi-domain] Cd Length: 432 Bit Score: 112.22 E-value: 5.80e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 13 QLIRFTLPTIGMMLFMSLYVMVDGFFVSNwCGQTALAAVNFAYPIPMILGTLGFMFGTGGSAIVAKTRGEGDDARANRQF 92
Cdd:cd13137 2 RIWSLAWPVILENLLQTLVGLVDVFMVGR-LGAEAIAAVGLATQVLWLLLVLNMALGTGTVALVSQSYGAGDYERARRAL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 93 SLLVYAAIVAGAAFAALGVLLLRPLLVALGAQGEMLDLCMVYAMPLVMGVPATVLQYLFQELLVTAGKPELGFGVTVAAG 172
Cdd:cd13137 81 GQSLLLALLLSLPLALLGLLFAEPLLRLLGADPEVIALALTYLRIVLLGIPFFFLSLVGNAALRGAGDTKTPMYIMIIVN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 173 LTNIVVDAVLI----ALLDFGVVGAAIGTIAGEAVGGIIPLVYFARPNKSF-LRLGRTNMDWRMLGHACVNGSSEMVSNI 247
Cdd:cd13137 161 VLNIVLDYVLIfglwGFPGLGVAGAALATVISRVVGALLLLFLLLRGRLPIkISFKGFRLDRKIIKKLLRIGLPAGLEQL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 248 AMSLVSMAYNVqLLVYLGESGVAAYGVIMYV-GMAFVAVFmGYVFGSSPLMSFQYGANNRIEMRSLFRKSLLFVSICGVA 326
Cdd:cd13137 241 LRSLGFLVLLA-IVASYGTAALAAYQIGLRIeSLAFMPGF-GFSMAASTLVGQNLGAGDPDEARRYGKRALRLGVLFMGL 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 327 MFIATRVFARPLALVFVGYSEgLAELTVHAMLLYSASLLIVGFNMYGSALFTALGNGLVSAIISFVRTLIFEIGAVFLLP 406
Cdd:cd13137 319 LGLLLFIFAPPLASLFTPDPE-VIELGVLYLRIVALSQPFLAISFVLSGALRGAGDTRPPLIINLISMWLVRLPLAYLLG 397
|
410
....*....|...
gi 1540040113 407 TLF--GADGIWVS 417
Cdd:cd13137 398 FVLglGLTGIWLA 410
|
|
| MATE_like_2 |
cd13149 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
11-414 |
3.75e-26 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240554 [Multi-domain] Cd Length: 434 Bit Score: 110.09 E-value: 3.75e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 11 LPQLIRFTLPTIGMMLFMSLYVMVDGFFVSNwCGQTALAAVNFAYPIPMILGTLGFMFGTGGSAIVAKTRGEGDDARANR 90
Cdd:cd13149 8 PRHLIKLTLPMIFGILAMLIFNLTDTFFVGK-LGTKELAAISFTFPVVLFLNSLTIGLGIGASAVISRAIGAGDRNKAKR 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 91 QFSLLVYAAIVAGAAFAALGVLLLRPLLVALGAQGEMLDLCMVYAMPLVMGVPATVLQYLFQELLVTAGKPELGFGVTVA 170
Cdd:cd13149 87 LATDSLILSLLLSVIVSLLGLFTIPPLFSLLGASGEILPLIVEYMAIWYLGLVFLVLPMVGNAIIRATGDTKRPSLVMLG 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 171 AGLTNIVVDAVLI----ALLDFGVVGAAIGTIAGEAVGGIIPLVYFARPNK----SFLRLGRTNMDWRMLGHACVNGSSE 242
Cdd:cd13149 167 AALVNVILDPILIfgfgPIPGMGIAGAAIATVISRALGLGAALYFLHYHHRlidfSEPSLKALFRSWKDILSIGIPAALS 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 243 MVSNIamslVSMAYNVQLLVYLGESGVAAYGVIMYVGMAFVAVFMGYVFGSSPLMSFQYGANNRIEMRSLFRKSLLFVSI 322
Cdd:cd13149 247 NILTP----LSAAFITALVATYGPAAVAAFGVATRIESFAFIIVMALSSALGPFVGQNWGAGQYERVQEGLKISLKFSLI 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 323 CGVAMFIATRVFARPLALVFVGYSEgLAELTVHAMLLYSASLLIVGFNMYGSALFTALGNGLVSAIISFVRTLIFEIGAV 402
Cdd:cd13149 323 YGAILGIVLALFAGWLASLFSAEPE-VIELITLYLLIVPIGYGGLGILIITSASFNALGKPLYSLGLNLIRVFLLYIPLA 401
|
410
....*....|..
gi 1540040113 403 FLLPTLFGADGI 414
Cdd:cd13149 402 YVGSHLLGFAGV 413
|
|
| MATE_like_12 |
cd13142 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
11-417 |
6.69e-21 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240547 [Multi-domain] Cd Length: 444 Bit Score: 94.57 E-value: 6.69e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 11 LPQLIRFTLPTIGMMLFMSLYVMVDGFFVSNWcGQTALAAVNFAYPIPMILGTLGFMFGTGGSAIVAKTRGEGDDARANR 90
Cdd:cd13142 10 LRTLLKLAWPIIVSNLLQVAYNLADTFWLGRL-GADAVAAPSISWPLIFLFISLGGGLTVAGTALVAQYTGAGDYDKANK 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 91 QFS-LLVYAAIVAGAAFAALGVLLLRPLLVALGAQGEMLDLCMVYAMPLVMGVPATVLQYLFQELLVTAGKPELGFGVTV 169
Cdd:cd13142 89 VAGqTFSFVIILSLILAVLGYILSRPLLLLLIGAPEEVYPLALAYLRIIFLGLPFMFIFFVFNSLLRGIGDTKTPMKIMF 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 170 AAGLTNIVVDAVLI----ALLDFGVVGAAIGTIAGEAVGGIIpLVYFARPNKSFLRLGRTNM--DWRMLGHACVNGsseM 243
Cdd:cd13142 169 GSVLLNVILDPLLIfgigPFPGLGVAGAALATVISRGIAAVI-GLYLLFKGRVGLKISLRDLkpDWEWLKKIFRIG---L 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 244 VSNIAMSLVSMAYNVQ--LLVYLGESGVAAYGVIMYVGMAFVAVFMGYVFGSSPLMSFQYGANNRIEMRSLFRKSLLFVS 321
Cdd:cd13142 245 PSSIEQSARALGFTVMtaLVAGFGTVVVAAYGIGNRIISLVFLPAFGLARATSTMVGQNLGAGQIDRAEEIVKKAALLIF 324
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 322 ICGVAMFIATRVFARPLALVFVGYSEGLAElTVHAMLLYSASLLIVGFNMYGSALFTALGNGLVSAIISFVRTLIFEIGA 401
Cdd:cd13142 325 LILVIGGVLAFLFAEPIVRVFINDPEVIKE-GADFLRIVAPSFPFFGLFQVINGAFRGSGHTLTAMIISILRLWVIRIPL 403
|
410
....*....|....*...
gi 1540040113 402 VFLL--PTLFGADGIWVS 417
Cdd:cd13142 404 AYLLayVLGLGVTGIWIA 421
|
|
| MATE_like_7 |
cd13133 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
9-376 |
2.68e-18 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240538 [Multi-domain] Cd Length: 438 Bit Score: 86.81 E-value: 2.68e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 9 FTLPQLIRFTLPTIGMMLFMSLYVMVDGFFVSnWCGQTALAAVNFAYPIPMILGTLGFMFGTGGSAIVAKTRGEGDDARA 88
Cdd:cd13133 2 GGYREILKIALPLVLSMLSQTVMGFTDRAFLG-RLSEVALAASGPAGVLYFAILMLFFGLSSGVQVFVAQYNGAGRYSRI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 89 NRQFSLLVYAAIVAGAAFAALGVLLLRPLLVALGAQGEMLDLCMVYAMPLVMGVPATVLQYLFQELLVTAGKPELGFGVT 168
Cdd:cd13133 81 GRVLWQGLYFSLLLAPLLALLSALAAPLLFLLLGHSPEVQALEVEYFRIRILGAPFSLLGAALRAFFSGIGRTRVVMVAN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 169 VAAGLTNIVVDAVLI----ALLDFGVVGAAIGTIAGEAVGGIIPLVYFARPN--KSFLRLGRTNMDWRMLGHACVNGSSE 242
Cdd:cd13133 161 LVMVVVNIVLDYALIfgklGFPAMGIAGAAIATVIAEAVSLLFFLLLLFRRKnrRRFGLRRAWRFDRELLRRILRLGLPS 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 243 MVsNIAMSLVSMAYNVQLLVYLGESGVAAYGVIMYVGMAFVAVFMGYVFGSSPLMSFQYGANNRIEMRSLFRKSLLFVSI 322
Cdd:cd13133 241 GL-QFFLDVGAFTVFFLLIGRLGTTELAATNIVFSINSLAFLPMIGLGIAVSSLVGQALGAGRPDLAMRVTRRGLKLALA 319
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*..
gi 1540040113 323 CGVAMFIATRVFARPLALVFVGYSEG--LAELTVHAMLLYSASLLIVGFNM-YGSAL 376
Cdd:cd13133 320 YMLLLGILFLLFPELLLSIFTPGADFalIAELAVPLLRFVAAYILFDALALvFAGAL 376
|
|
| matE |
TIGR00797 |
putative efflux protein, MATE family; The Multi Antimicrobial Extrusion (MATE) Family (TC 2.A. ... |
20-359 |
2.83e-16 |
|
putative efflux protein, MATE family; The Multi Antimicrobial Extrusion (MATE) Family (TC 2.A.66) The MATE family consists of probable efflux proteins including a functionally characterized multi drug efflux system from Vibrio parahaemolyticus, a putative ethionine resistance protein of Saccharomyces cerevisiae, and the functionally uncharacterized DNA damage-inducible protein F (DinF) of E. coli. These proteins have 12 probable TMS. [Transport and binding proteins, Other]
Pssm-ID: 273273 [Multi-domain] Cd Length: 342 Bit Score: 79.60 E-value: 2.83e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 20 PTIGMMLFMSLYVMVDGFFVSNWcGQTALAAVNFAYPIPMILGTLGFMFGTGGSAIVAKTRGEGDDARANRQFSLLVYAA 99
Cdd:TIGR00797 1 PAILANILQPLLGLVDTAFVGHL-GPVDLAAVSLGSSVFMFLFSILMGLGTATTALVAQAVGAGNYQRLGRQAQQSLLLA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 100 IVAGAAFAALGVLLLRPLLVALGAQGEMLDLCMVYAMPLVMGVPATVLQYLFQELLVTAGKPELGFGVTVAAGLTNIVVD 179
Cdd:TIGR00797 80 LLLGLPVLLVGYFFIDPLLSLMGADGEVAELAQDYLRILILGIPAYLLNFVLRGFLRGQGDTKTPMYITLIGNVINIILN 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 180 AVLI--ALLDFGVVGAAIGTIAGEAVGGIIPLVYFARPNKSFLR-LGRTNMDWRMLGHACVNGSSEMVSNIAMSLVSMAY 256
Cdd:TIGR00797 160 YILIfgKFGFLGIVGAALATVISYWLMFLLLLYYIKKAKKIGLKwEGLLKPDWEVLKRLLKLGLPIAFRVILESLSFALL 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 257 NVqLLVYLGESGVAAYGVIMYVGMAFVAVFMGYVFGSSPLMSFQYGANNRIEMRSLFRKSLLFVSICGVAMFIATRVFAR 336
Cdd:TIGR00797 240 AL-LVARLGSIALAAHQIALNVESLLFMPAFGFGIAVSILVGQALGAGDPKRAKEVARVALKLSLLLGLVLAIILILFRE 318
|
330 340
....*....|....*....|...
gi 1540040113 337 PLALVFVGYSEgLAELTVHAMLL 359
Cdd:TIGR00797 319 FIARLFTNDPE-VLELAAIYLIF 340
|
|
| MATE_DinF_like |
cd13136 |
DinF and similar proteins, a subfamily of the multidrug and toxic compound extrusion (MATE) ... |
13-417 |
5.92e-15 |
|
DinF and similar proteins, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Escherichia coli DinF is a membrane protein that has been found to protect cells against oxidative stress and bile salts. The expression of DinF is regulated as part of the SOS system. It may act by detoxifying oxidizing molecules that have the potential to damage DNA. Some member of this family have been reported to enhance the virulence of plant pathogenic bacteria by enhancing their ability to grow in the presence of toxic compounds. Proteins from the MATE family are involved in exporting metabolites across the cell membrane and are often responsible for multidrug resistance (MDR).
Pssm-ID: 240541 [Multi-domain] Cd Length: 424 Bit Score: 76.45 E-value: 5.92e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 13 QLIRFTLPTIGMMLFMSLYVMVDGFFVSNWCGQTALAAVNFAypiPMILGTLGFMFG---TGGSAIVAKTRGEGDDARAN 89
Cdd:cd13136 4 EILALALPAILSNITVPLLGLVDTAVVGHLGSAAYLGAVALG---TTIFNTLFWLFGflrMGTTGLVAQALGAGDREEAI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 90 RQFSLLVYAAIVAGAAFAALGVLLLRPLLVALGAQGEMLDLCMVYAMPLVMGVPATVLQYLFQELLVTAGKPELGFGVTV 169
Cdd:cd13136 81 ALLVRALLLALAIGLLLILLQSPLLALALLLLGASAAVAALARQYLRIRILGAPAVLLNYVATGWFRGLQDTRTPLILQI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 170 AAGLTNIVVDAVLIALLDFGVVGAAIGTIAGEAVGGIIPLVYFARP-NKSFLRLGRTNMDWRMLGHACVNGSSEMVSNIA 248
Cdd:cd13136 161 VGNVVNIVLDPLFVFGLGWGVAGAALATVIAQYLGALLGLWLLRRRvRLLGKSLSRRLPSKAALKRLFKLNRDIFIRTLA 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 249 MsLVSMAYNVQLLVYLGESGVAAYGVIMYVGMAFVAVFMGYVFGSSPLMSFQYGANNRIEMRSLFRKSLLFVSICGVAMF 328
Cdd:cd13136 241 L-LAAFLFFTALAARLGDVILAANQILLQFWLLSSYFLDGFAYAAEALVGRALGAGDRKAARRVARRLLQWGLGLGVLLA 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 329 IATRVFARPLALVFVGYSEGLAELTVHAMLLYSASLL-IVGFNMYGSAL----FTALGNGLVSAIISFvrtlifeIGAVF 403
Cdd:cd13136 320 LLFFLGGEPIIRLFTDDPAVLALAATYLPWLALLPPIgALAFVLDGIFIgatdTRYLRNSMLVSLAVF-------LPLLF 392
|
410
....*....|....
gi 1540040113 404 LLPTLFGADGIWVS 417
Cdd:cd13136 393 LLVPLWGNHGLWLA 406
|
|
| MATE_like_1 |
cd13140 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
10-417 |
3.02e-14 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. MATE has also been identified as a large multigene family in plants, where the proteins are linked to disease resistance. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240545 [Multi-domain] Cd Length: 435 Bit Score: 74.48 E-value: 3.02e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 10 TLPQLIRFTLPTIGMMLFMSLYVMVDGFFVSNwCGQTALAAVNFAYPIPMILGTLGFMFGTGGSAIVAKTRGEGDDARAN 89
Cdd:cd13140 3 ILKTLLRLALPIMGTSFIQMAYNLTDMFWVGR-LGSDAVAAVGTAGFFVWLAYALALLSKIGAQVKVSQSIGAKDEKEAR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 90 R--QFSLLVYAAIVAGAAFAALGVLLLRPLLVALGAQgEMLDLCMVYAMPLVMGVPATVLQYLFQELLVTAGKPELGFGV 167
Cdd:cd13140 82 KyaRNALQLNLLLGILYGLLLLLFAKPLIGFFNLGDA-EVISLAITYLRIVALGLIFSFLNPVFTGIFNALGDSKTPFII 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 168 TVAAGLTNIVVDAVLI----ALLDFGVVGAAIGTIAGEAVGGIIPLVYFARPNKSFLRLG-RTNMDWRMLGHACVNGSSE 242
Cdd:cd13140 161 NAIGLVLNIILDPLLIfgfgPFPALGVAGAALATVLAQAIVFLLFLYALKKKKGLFLKIRiLKRPDRKYIKEILKLGLPV 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 243 MVSNIAMSLVSMAYNvQLLVYLGESGVAAYGVimyvGMAFVAV-FM---GYVFGSSPLMSFQYGANNRIEMRSLFRKSLL 318
Cdd:cd13140 241 ALQSILFALISMILA-RIIASFGPVAIAAQKV----GSQIESIsWMtaeGFSTALAAFVGQNYGAGKYDRIRKGYKTALK 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 319 FVSICGVAMFIATRVFARPLALVFVGYSEGLAELTVHAMLLySASLLIVGFNMYGSALFTALGNGLVSAIISFVRTLIFE 398
Cdd:cd13140 316 IASAIGLFATLLLFFFGEPLFSLFIPDPETIAIGVDYLRIL-GFSQLFMCLEITTTGAFNGLGRTKPPAIISIVFNGLRI 394
|
410
....*....|....*....
gi 1540040113 399 IGAVFLLPTLFGADGIWVS 417
Cdd:cd13140 395 PLALLLSPTGLGLNGIWWA 413
|
|
| MATE_like_6 |
cd13146 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
11-410 |
4.44e-14 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240551 [Multi-domain] Cd Length: 433 Bit Score: 73.97 E-value: 4.44e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 11 LPQLIRFTLPTIGMMLFMSLYVMVDGFFVS--NWCGQTALAAVNFAYPIPMILGTLGFMFGTGGSAIVAKTRGEGDDARA 88
Cdd:cd13146 7 SPLLIRLALPILIGQLFQLLYNITDTIWISmiDPSDPALVGGIGLVFPLGMIFLALGNGIQVGVSSLLARAIGAQRAKEL 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 89 NRQFSLLVYAAIVAGAAFAALGVLLLRPLLVALGAQGEMLDLCMVYAMPLVMGVPATVLQYLFQELLVTAGKPELGFGVT 168
Cdd:cd13146 87 DQAADSGLALALLAATVIVVLGYIFAEPLLQLLGAKGLLLEYALEYFYYSLPGVPFIMLIGVLMGVLQGEGRTKYMMMAM 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 169 VAAGLTNIVVDAVLIALLDFGVVGAAIGTIAGEAVGGIIPLVYF-ARPNKSFLRLGRTNMDWRMLGHACVNGSSEMVSNI 247
Cdd:cd13146 167 LIGTVVNIVLDPILIFVFDMGVKGAALATVLAQAISLLYLLYVFlIGKSNVTIHIKLSNISSSVIVEILRVGLPQMLLQL 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 248 AMSLVSMAYNvQLLVYLGESGVAAYgvIMYVGMAFVAVFMGYVFGSSPL--MSFQYGANNRIEMRSLFRKSLLfVSICGV 325
Cdd:cd13146 247 ISSISFLIYN-RIIIDIDPVAMTAF--TLVGRLDQFILIPIFAISSALLtiAGQNWGRGNYDRMLQILMTAVI-LGIVVV 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 326 AMFIATRVFARPLALVFVGYSEGLAELTVHAMLLYSASLLIVGFNMYGSALFTALGNGLVSAIISFVRTLIFEIGAVFLL 405
Cdd:cd13146 323 LVLVLGYVLVAPWLFSLFTTVPEVVAYAVLQVRTMALALPFVAISILVTEFFQAIGKAWPSLLLTLIRHVFLSVPVVYLL 402
|
....*
gi 1540040113 406 PTLFG 410
Cdd:cd13146 403 AYVFG 407
|
|
| MATE_like_14 |
cd13139 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
22-417 |
8.66e-14 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240544 [Multi-domain] Cd Length: 448 Bit Score: 73.03 E-value: 8.66e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 22 IGMMLFM---SLYVMVDGFFVSNwCGQTALAAVNFAYPIPMILGTLGFMFGTGGSAIVAKTRGEGDDARANRQFSLLVYA 98
Cdd:cd13139 21 IPMVLEMvmeSLFAVVDLYFVSR-LGALAIATVGLTESVLTIVYSIAIGLSMAATALVARRIGEKDPEGAGFAAVQAILL 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 99 AIVAGAAFAALGVLLLRPLLVALGAQGEMLDLCMVYAMPLVMGVPATVLQYLFQELLVTAGKPELGFGVTVAAGLTNIVV 178
Cdd:cd13139 100 GVALSLILSILGYFFAEDILSLMGASPAVIAEGYGYTRIMFGGNGFIMLLFLINGIFRGAGDAAIAMRSLWLANGLNIIL 179
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 179 DAVLIALL----DFGVVGAAIGTIAGEAVGGIIPLVYFARpNKSFLRLGRTNMD------WRMLGHAcVNGSSEMVsnIA 248
Cdd:cd13139 180 DPLFIFGLgpipAMGVTGAAIATTIGRSIGVLYQLYHLFK-GKGRIQIRRRHLKldwaiiKKIIKIA-VGGILQFL--IA 255
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 249 MSlvSMAYNVQLLVYLGESGVAAYGVIMYVGMAFVAVFMGYVFGSSPLMSFQYGANN--RIEmRSLFRK---SLLFVSIC 323
Cdd:cd13139 256 SS--SWIFLVRIIAEFGSTALAGYTIAIRIIMFALLPAWGLSNAAATLVGQNLGAGQpdRAE-KSVWRAgkyNMVFLGIV 332
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 324 GVAMFIatrvFARPLALVFVGySEGLAELTVHAMLLYSASLLIVGFNMYGSALFTALGNGLVSAIISFVRTLIFEIGAVF 403
Cdd:cd13139 333 SLVFFL----FAEPLVSFFTT-DPEVIAIAVEALRIISLGYIFYGYGMVLSQAFNGAGDTKTPTLINLVGFWLFQIPLAY 407
|
410
....*....|....*.
gi 1540040113 404 LL--PTLFGADGIWVS 417
Cdd:cd13139 408 LLarHLNLGPKGVFIA 423
|
|
| MATE_like_13 |
cd13141 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
14-404 |
3.34e-13 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240546 [Multi-domain] Cd Length: 443 Bit Score: 71.19 E-value: 3.34e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 14 LIRFTLPTIGMMLFMSLYVMVDGFFVSNwCGQTALAAVNFAYPIPMILGTLGFMFGTGGSAIVAKTRGEGDDARANRQFS 93
Cdd:cd13141 13 IISMALPIAIGMIIQTLYFLVDLYFVGQ-LGDAALAGVSLAGNVMFFVMALTQVLNVGTAALVSHAVGRKDQGEANAVFN 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 94 LLVYAAIVAGAAFAALGVLLLRPLLVALGAQGEMLDLCMVYampLVMGVPATVLQYLFQEL---LVTAGKPELGFGVTVA 170
Cdd:cd13141 92 QSLLLAAVLGLVVLVLGYLFGRLYLETLAADAATVEAATTY---LYWFIPSLALQFILTVLgaaLRGTGIVKPFMVIQIL 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 171 AGLTNIVVDAVLIA----LLDFGVVGAAIGTIAGEAVGGIIPLVYFARPNKSF---LRLGRTNMD-WRMLGHACVNGSSE 242
Cdd:cd13141 169 AVLLNIILAPILITgwgtGRALGVAGAGLASSISVAIAVVLLLYYFLRLEKYLrldLALWRPDLPtWKRLLKIGLPSGGE 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 243 MvsniAMSLVSMAYNVQLLVYLGESGVAAYGVIMYVGMAFVAVFMGYVFGSSPLMSFQYGANNRIEMRSLFRKSLLFVSI 322
Cdd:cd13141 249 F----LLTFVYMAVIYWALRPFGAAAQAGFGIGSRIMQSLFLPAMAIAFAAPAIAGQNFGAGNYDRVRETFRITAILTTA 324
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 323 cgvAMFIATRVFARPLALVFVGYSEGLAELTVHAMLLYSASLLIV--GFNMYGSALFTALGNGLVSAIISFVRTLIFEIG 400
Cdd:cd13141 325 ---LMLVLTLLCQLVPELLVTPFSDDAAVIAVAATFLRYVSWNFVaaGLVFTCSGMFQALGNTWPSLLSSASRLLTFALP 401
|
....
gi 1540040113 401 AVFL 404
Cdd:cd13141 402 VIWL 405
|
|
| MatE |
pfam01554 |
MatE; The MatE domain |
243-396 |
7.36e-12 |
|
MatE; The MatE domain
Pssm-ID: 334587 [Multi-domain] Cd Length: 161 Bit Score: 63.35 E-value: 7.36e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 243 MVSNIAMSLVSMAYNVqLLVYLGESGVAAYGVIMYVGMAFVAVFMGYVFGSSPLMSFQYGANNRIEMRSLFRKSLLFVSI 322
Cdd:pfam01554 3 ALENLLQSLYSLIDTL-FVGHLGAVALAAVSIANSIASLIFMFLLGLGTALTTLVGQALGAGNFKRAGVALRQGLILGLL 81
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1540040113 323 CGVAMFIATRVFARPLALVFvGYSEGLAELTVHAMLLYSASLLIVGFNMYGSALFTALGNGLVSAIISFVRTLI 396
Cdd:pfam01554 82 LSLPIALLVLLFSEPILSLF-GQDEEVLALAKRYLRILILGIPFYALQFVLSGFLRGQGDTKPPMYINIISLLL 154
|
|
| MATE_like_5 |
cd13145 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
11-417 |
2.89e-11 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240550 [Multi-domain] Cd Length: 440 Bit Score: 65.31 E-value: 2.89e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 11 LPQLIR-FTLPTIGMMLFMSLYVMVDGFFVSnWCGQTALAAVNFAYPIPMILGTLGFMFGTGGSAIVAKTRGEGDDARAN 89
Cdd:cd13145 7 IPKLIRkLAIPASVGFFFNTMFNVVDTFFAG-KISTEALAALSLSFPIFFIIIAIGVGIGTGTTALIGNALGAGDRRKAR 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 90 RQFSLLVYAAIVAGAAFAALGVLLLRPLLVALGAQGEMLDLCMVYAMPLVMGVPATVLQYLFQELLVTAGKPELGFGVTV 169
Cdd:cd13145 86 RYAAQGLSFGIILAILLTVIGLFAAPPLFRLLGAEGDYLDLALEYMDVIFAGSIFFLLNFGLNGILNAQGDTKSYRNFLI 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 170 AAGLTNIVVDAVLI----ALLDFGVVGAAIGTIAGEAvGGIIPLVYFARPNKSFLRLGRTNM--DWRMLGHACVNGSSEM 243
Cdd:cd13145 166 IGFFLNIILDPLFIfgggGIPAMGVSGIALATIISQF-IGMFYLLYKVRKSGIISGCRLRDFipRLDVYKEILKQGFPAS 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 244 VSNIAMSLVSmaYNVQLLV-YLGESGVAAYGVIMYVGMAFVAVFMGYVFGSSPLMSFQYGANNRIEMRSLFRKSLLF-VS 321
Cdd:cd13145 245 LNMMTIGLGI--FVITYFVgQFGDEAVAAYGIALRIEQILLLPTIGLNTAVLSIAGQNFGAKKYDRVRETYKKALKYgFV 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 322 ICGVAMFIAtRVFARPLALVFVGYSE----GLAELTVHAMLLYSASLLivgfNMYGSALfTALGNGLVSAIISFVRTLIF 397
Cdd:cd13145 323 IMVVATVFL-LFFAEPLMSLFTNDPAviaiGAGYLRIDALIFYAYVVL----FISVSVL-QGLKRPIFALWIGLYRQLVG 396
|
410 420
....*....|....*....|..
gi 1540040113 398 EIGAVFLLPTLFGAD--GIWVS 417
Cdd:cd13145 397 PALVFWLLVNVLGLGvtGIWWG 418
|
|
| MATE_like_8 |
cd13134 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
10-342 |
9.17e-10 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240539 [Multi-domain] Cd Length: 438 Bit Score: 60.59 E-value: 9.17e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 10 TLPQLIRFTLPTIGMMLFMSLYVMVDGFFVSnWCGQTALAAVNFAYPIPMILGTLGFMFGTGGSAIVAKTRGEGDDARAN 89
Cdd:cd13134 1 FKLSLFALAWPIFIELLLQMLLGTIDTFMLS-RYSDNAVAAVGVANQILFLLILIFSFISTGTSILIAQYLGAKDKKKAR 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 90 RQFSLLVYAAIVAGAAFAALGVLLLRPLLVALGAQGEMLDLCMVYAMPLVMGVPATVLQYLFQELLVTAGKPELGFGVTV 169
Cdd:cd13134 80 QIAGVALLFNLLLGLVFSLLLLFFGAELLRLMGLPPELLALGSTYLRIVGGSLFLQALSLTLSAILRSHGRTKIPMYVSL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 170 AAGLTNIVVDAVLI----ALLDFGVVGAAIGTIAGEAVGGIIPLVYFARPNKSFLRL----GRTNMDWRMLGHACVNGSS 241
Cdd:cd13134 160 IMNILNIVGNYLLIfgwfGLPKLGVAGVAISTVISRAVGLVLLFILLFRKLKIRFRLkdlrPFPKKLLKKILKIGLPSAG 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 242 EMVS-NIAMSLVSMAYNvqllvYLGESGVAAYGVIMYVGMAFVAVFMGYVFGSSPLMSFQYGANNRIEMRSLFRKSLLFV 320
Cdd:cd13134 240 EELSyNLSQTVITAFIA-----RLGTAALAARTYASNISMFVFLFSLAIGQATQIIVGHLVGAGDFDEAYKRVLKSLKIG 314
|
330 340
....*....|....*....|..
gi 1540040113 321 SICGVAMFIATRVFARPLALVF 342
Cdd:cd13134 315 LLVSLAVALLLALFREPILGLF 336
|
|
| MatE |
pfam01554 |
MatE; The MatE domain |
20-181 |
9.67e-10 |
|
MatE; The MatE domain
Pssm-ID: 334587 [Multi-domain] Cd Length: 161 Bit Score: 57.19 E-value: 9.67e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 20 PTIGMMLFMSLYVMVDGFFVSNWcGQTALAAVNFAYPIPMILGTLGFMFGTGGSAIVAKTRGEGDDARANRQFSLLVYAA 99
Cdd:pfam01554 1 PIALENLLQSLYSLIDTLFVGHL-GAVALAAVSIANSIASLIFMFLLGLGTALTTLVGQALGAGNFKRAGVALRQGLILG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 100 IVAGAAFAALGVLLLRPLLVALGAQGEMLDLCMVYAMPLVMGVPATVLQYLFQELLVTAGKPELGFGVTVAAGLTNIVVD 179
Cdd:pfam01554 80 LLLSLPIALLVLLFSEPILSLFGQDEEVLALAKRYLRILILGIPFYALQFVLSGFLRGQGDTKPPMYINIISLLLNIPLN 159
|
..
gi 1540040113 180 AV 181
Cdd:pfam01554 160 YL 161
|
|
| MATE_like_3 |
cd13148 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
11-232 |
3.75e-08 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240553 [Multi-domain] Cd Length: 441 Bit Score: 55.36 E-value: 3.75e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 11 LPQLIRFTLPTIGMMLFMSLYVMVDGFFVSNwCGQTALAAVNFAYPIPMILGTLGF-MFGTGGSAIVAKTRGEGDDARAN 89
Cdd:cd13148 11 LPTLLRLALPNILALLVQTLVGLAETYFVGQ-LGTDALAGVALVFPLLMLTQMMSNgAMGGGVSSAIARALGAGDRERAE 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 90 RQFSLLVYAAIVAGAAFAALGVLLLRPLLVALGAQGEMLDLCMVYAMPLVMGVPATVLQYLFQELLVTAGKPELGFGVTV 169
Cdd:cd13148 90 ALVWHALVIALAGGLVFSLLFLLFGPALYRLLGGRGEALDAALAYSNVLFSGAILIWLVNLLAAALRGTGNMRVPALVTL 169
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1540040113 170 AAGLTNIVVDAVLI----ALLDFGVVGAAIGTIAGEAVGGIIPLVYFARPNKSF-LRLGRTNMDWRML 232
Cdd:cd13148 170 VGAVVQIPLSPGLIlgwgPLPRLGVAGAAVAAVLYYALAALVLLRYLASGRSRLrLRLRALRLERRLF 237
|
|
| MATE_like |
cd12082 |
Multidrug and toxic compound extrusion family and similar proteins; The integral membrane ... |
13-212 |
2.67e-07 |
|
Multidrug and toxic compound extrusion family and similar proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. MATE has also been identified as a large multigene family in plants, where the proteins are linked to disease resistance. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240527 [Multi-domain] Cd Length: 420 Bit Score: 52.71 E-value: 2.67e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 13 QLIRFTLPTIGMMLFMSLYVMVDGFFVSNWCGQTALAAVNFAYPIPMILGTLGFMFGTGGSAIVAKTRGEGDDARANRQF 92
Cdd:cd12082 220 RLLRIGLPSAIQNSLLSLGLLIIVAIVAAFGGAAALAAYTVAFRIASLAFMPALGLAQAALPVVGQNLGAGNFDRARRIT 299
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 93 SLLVYAAIVAGAAFAALGVLLLRPLLVALGAQGEMLDLCMVYAMPLVMGVPATVLQYLFQELLVTAGKPELGFGVTVAAG 172
Cdd:cd12082 300 WVALLIGLLIGAVLGLLILLFPEPILSLFTNDPEFLELAVSYLRILAIYYLFVGIGYVLQAGFQAAGRTLKSLIVSLLSY 379
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 1540040113 173 LTNIVVDAVLIALLDFGVVGAAIGTIAGEAVGGIIPLVYF 212
Cdd:cd12082 380 WVVRLPLAYVLAYLGLGLYGIWLALVISLILAALVLLLFF 419
|
|
| MATE_MurJ_like |
cd13123 |
MurJ/MviN, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; ... |
165-414 |
1.47e-05 |
|
MurJ/MviN, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Escherichia coli MurJ (MviN) has been identified as essential for murein biosynthesis. It has been suggested that MurJ functions as the peptidoglycan lipid II flippase which is involved in translocation of lipid-anchored peptidoglycan precursors across the cytoplasmic membrane, though results obtained in Bacillus subtilis seem to indicate that its MurJ homologs are not essential for growth. Some MviN family members (e.g. in Mycobacterium tuberculosis) possess an extended C-terminal region that contains an intracellular pseudo-kinase domain and an extracellular domain resembling carbohydrate-binding proteins. Proteins from the MATE family are involved in exporting metabolites across the cell membrane and are often responsible for multidrug resistance (MDR).
Pssm-ID: 240528 [Multi-domain] Cd Length: 420 Bit Score: 47.06 E-value: 1.47e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 165 FGVTVAAG-LTNIVVDAVLIAL---LDFGVVGAAIGTIAGEAVGGIIPLVYFARPNKSF-LRLGRTN---------MDWR 230
Cdd:cd13123 145 FFAPALAPvLLNLVIIAGLLLLaplFDLGIYALAWGVLLGGVLQLLVQLPALRRLGFRFrPRLDFRDpgvrrvlklMLPA 224
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 231 MLGHACVNGSSEMVSNIAMSL----VSMAYNVQLLVYLgesgvaAYGVImyvGMAFVAVFMgyvfgssPLMSFQYGANNR 306
Cdd:cd13123 225 LLGVSVSQINLLVDTILASFLpegsISALYYADRLYQL------PLGIF---GVAIATALL-------PRLSRLAAAGDL 288
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 307 IEMRSLFRKSLLFVSICGVAMFIATRVFARPLALVFVGY---SEGLAELTVHAMLLYSASLLIVGFNMYGSALFTALGNG 383
Cdd:cd13123 289 DEFRRTLSRGLRLVLFLLLPAAVGLIVLAEPIVRLLFERgafTAEDTLMTASALAAYALGLPAFALVKLLSRAFYALKDT 368
|
250 260 270
....*....|....*....|....*....|.
gi 1540040113 384 LVSAIISFVrTLIFEIGAVFLLPTLFGADGI 414
Cdd:cd13123 369 KTPVKIAVI-AVAVNILLNLLLIKPLGHVGL 398
|
|
| RfbX |
COG2244 |
Membrane protein involved in the export of O-antigen and teichoic acid [Cell wall/membrane ... |
243-414 |
1.90e-05 |
|
Membrane protein involved in the export of O-antigen and teichoic acid [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 441845 [Multi-domain] Cd Length: 366 Bit Score: 46.48 E-value: 1.90e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 243 MVSNIAMSLVSMAYNVQLLVYLGESGVAAYGVIMYVGMAFVAVFMGYVFGSSPLMSFQYGANNRIEMRSLFRKSLLFVSI 322
Cdd:COG2244 183 LLSGLLGLLLTNLDRLLLGALLGPAAVGIYSAAYRLASLLLLLITALSQVLFPRLSRLLAEGDREELRRLYRKALRLLLL 262
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 323 CGVAMFIATRVFARPLALVFVG--YSEGlaeltVHAMLLYSASLLIVGFNMYGSALFTALGNGLVSAIISFVRTLIFeIG 400
Cdd:COG2244 263 LGLPLALGLALLAPPLLSLLFGpeYAEA-----APVLPILALGALFLALSGVLSNLLLALGRTRLLLIISLIGAVLN-LV 336
|
170
....*....|....
gi 1540040113 401 AVFLLPTLFGADGI 414
Cdd:COG2244 337 LNLLLIPRYGLVGA 350
|
|
| MurJ |
COG0728 |
Lipid II flippase MurJ/MviN (peptidoglycan biosynthesis) [Cell wall/membrane/envelope ... |
165-414 |
2.11e-05 |
|
Lipid II flippase MurJ/MviN (peptidoglycan biosynthesis) [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440492 [Multi-domain] Cd Length: 503 Bit Score: 46.68 E-value: 2.11e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 165 FGVTVAAG-LTNIVVDAVLIAL---LDFGVVGAAIGTIAGEAVGGIIPLVYFARPNKSF-LRLGRTNMDWRMLGHACVNg 239
Cdd:COG0728 152 FAAPALAPvLLNLVIIAGLLLLaplFGPGIYALAWGVLLGGVLQLLIQLPALRRLGLRLrPRFDLRDPGVRRVLKLMLP- 230
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 240 sseMVSNIAMSLVSMAYNVQLLVYLGESGVAAYgvimYVGMAFVAVFMGyVFGSS------PLMSFQYGANNRIEMRSLF 313
Cdd:COG0728 231 ---ALLGVSVSQINLLVDTILASFLPEGSVSAL----YYADRLYQLPLG-LFGVAigtallPRLSRAAAAGDLEEFRRTL 302
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 314 RKSLLFVSICGVAMFIATRVFARPLALVFVGY---SEGLAELTVHAMLLYSASLLIVGFNMYGSALFTALGNGLVSAIIS 390
Cdd:COG0728 303 SRGLRLVLLLTLPAAVGLIVLAEPIVRLLFERgafTAEDTALTALALAAYALGLPAFALVKVLARAFYARQDTRTPVRIA 382
|
250 260
....*....|....*....|....
gi 1540040113 391 FVrTLIFEIGAVFLLPTLFGADGI 414
Cdd:COG0728 383 VI-AVVVNIVLNLLLVPPLGHAGL 405
|
|
| MATE_like_9 |
cd13135 |
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The ... |
12-384 |
9.32e-05 |
|
Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240540 [Multi-domain] Cd Length: 429 Bit Score: 44.59 E-value: 9.32e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 12 PQLIRFTLPTIGMMLFMSLYVMVDGFFVSNWCGQTALAAVNFAYPIPMILGTLGFMfGTGGSAIVAKTRGEGDDARANRQ 91
Cdd:cd13135 1 KKINHIAIPLILQNLVSQLQMLVDRAFLGRISIRYYSAVGNVTTPFNTITGFLGSI-SIGFTILGSQSVGAKDIKRINDY 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 92 FSLLVYAAIVAGAAFAALGVLLLRPLLVALGAQGEMLDLCMVYAMPLVMGVPATVLQYLFQELLVTAGKPELGFGVTVAA 171
Cdd:cd13135 80 AISSIVYNSIIGVILFLLWLFGARIIFVLFGVDGQILGYSINYVRIFSIYLLLLGILFTFSSILQGIGETKPIMYGGIIK 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 172 GLTNIVVDAVLI----ALLDFGVVGAAIGTIAGEAVGGIIPLVYFARPNKSFLRLGRTNMD---WRMLGHACVNGSSEMV 244
Cdd:cd13135 160 NLLNVILDYVLIfgnfGFPRLGIIGAAIATTIANVLNLIILVYLCRKIKKLTFKLSNTKVLkanIRPYKFTIKLGLPLGG 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 245 SNIAMSLVSMAYNvQLLVYLGESGVAAYGVIMYVGMAFVAVFMGYVFGSSPLMSFQYGANNRIEMRSLFRKSLLFVSICG 324
Cdd:cd13135 240 EEFLWNIGNLAVI-RILNRIGELALGIYTLVFGIENIVLMPMYGYSSAALTLVGESIGKKDLKEALRIGNICLGLGLLIY 318
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 325 VAMFIATRVFARPLALVFVGYSEGLAELTVHamllysasLLIVGFNMYGSALFTALGNGL 384
Cdd:cd13135 319 IAAAIVFLAFPYKILSLFTNDPELINYSIPY--------LIFIIIILFFKSINIVYGFAI 370
|
|
| MATE_like |
cd12082 |
Multidrug and toxic compound extrusion family and similar proteins; The integral membrane ... |
243-396 |
1.14e-04 |
|
Multidrug and toxic compound extrusion family and similar proteins; The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. MATE has also been identified as a large multigene family in plants, where the proteins are linked to disease resistance. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.
Pssm-ID: 240527 [Multi-domain] Cd Length: 420 Bit Score: 44.24 E-value: 1.14e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 243 MVSNIAMSLVSMAYNVQLLVYLGESG---VAAYGVIMYVGMAFVAVFMGYVFGSSPLMSFQYGANNRIEMRSLFRkSLLF 319
Cdd:cd12082 1 AAPLLLSMLLQTLYNLVDTFFLGRLLgdaLAAVGLAFPLIALLIALGVGLSVGTSALISQAIGAGDEEKARRVLV-QSIV 79
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1540040113 320 VSICGVAMFIATRVFARPLALVFVGYSEGLAELTVHAMLLYSASLLIVGFNMYGSALFTALGNGLVSAIISFVRTLI 396
Cdd:cd12082 80 LAILLGLLLAALLLFFSPLILSLLGAEEEVIELAATYLTILILGLPITFLGAVLSGILQGEGDTRTAMIISVLSNLL 156
|
|
| MATE_Wzx_like |
cd13128 |
Wzx, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; ... |
180-413 |
3.58e-03 |
|
Wzx, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Escherichia coli Wzx and related proteins from other gram-negative bacteria are thought to act as flippases, assisting in the membrane translocation of lipopolysaccharides including those containing O-antigens. Proteins from the MATE family are involved in exporting metabolites across the cell membrane and are often responsible for multidrug resistance (MDR).
Pssm-ID: 240533 [Multi-domain] Cd Length: 402 Bit Score: 39.45 E-value: 3.58e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 180 AVLIALLDFGVVGAAIGTIAGEAVGGIIpLVYFARPNKSFLRLGRTNMDW--RMLGHacvnGSSEMVSNIAMSLVSMAYN 257
Cdd:cd13128 156 ALILVLLGGGLIGFALAYLIASVLSAIL-LLYIYRKKILLPKFFSFDLKLakELLRF----SIPLALSGIFSLIYTRIDT 230
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1540040113 258 VQLLVYLGESGVAAYGVIMYVGMAFVAVFMGYVFGSSPLMSfQYGANNRIEMRSLFRKSLLFVSICGVAMFIATRVFARP 337
Cdd:cd13128 231 IMLGYFLGDAAVGIYNAAYRIAELLLFIPSAISTALFPRIS-ELYKNDKDELKKLLKKSFKYLFLISLPIAIGLFLFAEP 309
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1540040113 338 LALVFVG--YSEGlaeltVHAMLLYSASLLIVGFNMYGSALFTALGNGLVSAIISFVrTLIFEIGAVFLLPTLFGADG 413
Cdd:cd13128 310 IITLLFGeeYLPA-----ALVLQILAWGFLFIFLNGIFGSILQAIGKQKLTLKILLI-GALLNVILNLLLIPKYGIIG 381
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